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4100
[ "Chapman", "'s", "estimate", "suggests", "483", "(", "95", "%", "C.I.", "383", "-", "634", ")", "nHSV", "cases", "occurred", "(", "31.5", "infections", "per", "100,000", "live", "births", ")", "." ]
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4101
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4102
[ "Log", "-", "linear", "modeling", "estimates", "35.8", "fatal", "cases", "occurred", "(", "95", "%", "CI", "34", "-", "40", ")", "." ]
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4103
[ "CONCLUSIONS", ":", "Chapman", "'s", "estimates", "using", "data", "collected", "over", "7", "years", "in", "Florida", ",", "conclude", "nHSV", "infections", "occurred", "at", "a", "rate", "of", "1", "per", "3000", "live", "births", "." ]
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4104
[ "Background", "Congenital", "malformations", "are", "described", "in", "about", "3", "%", "of", "live", "births", "and", "20", "%", "of", "stillbirths", "in", "the", "industrialized", "countries", "." ]
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4105
[ "The", "prevalence", "of", "congenital", "anomalies", "in", "developing", "countries", ",", "including", "Morocco", ",", "is", "not", "well", "known", "at", "the", "national", "level", "." ]
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4106
[ "The", "aim", "of", "our", "study", "is", "to", "conduct", "a", "descriptive", "exploratory", "analysis", "of", "congenital", "malformations", "cases", "diagnosed", "at", "the", "Les", "Orangers", "Maternity", "and", "Reproductive", "Health", "Hospital", "in", "Rabat", "." ]
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4107
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4108
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4109
[ "Total", "and", "specific", "prevalences", "were", "calculated", "for", "each", "malformation", "." ]
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4110
[ "A", "principal", "component", "analysis", "(", "PCA", ")", "was", "then", "conducted", "followed", "by", "a", "Varimax", "rotation", "in", "order", "to", "identify", "the", "different", "associations", "of", "malformations", "in", "our", "series", "." ]
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4111
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4112
[ "A", "polymalformative", "syndrome", "was", "found", "in", "26.5", "%", "of", "cases", "which", "makes", "a", "total", "number", "of", "470", "anomalies", "." ]
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4113
[ "The", "musculoskeletal", "anomalies", "predominate", "with", "a", "rate", "of", "33", "%", ",", "followed", "by", "neurological", "abnormalities", "18", "%", ",", "of", "whom", "31", "%", "were", "hydrocephalus", ",", "26.2", "%", "anencephaly", ",", "and", "20.24", "%", "spina", "bifida", "." ]
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4114
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4115
[ "The", "antenatal", "diagnosis", "of", "congenital", "malformations", "was", "performed", "in", "28.6", "%", "of", "cases", "." ]
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4116
[ "Conclusions", "Our", "study", "provides", "a", "general", "overview", "of", "the", "epidemiological", "situation", "related", "to", "different", "types", "of", "congenital", "anomalies", "for", "a", "specific", "area", "in", "Morocco", "." ]
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4117
[ "It", "represents", "a", "database", "that", "should", "be", "complemented", "by", "other", "multicenter", "studies", "and", "the", "implementation", "of", "a", "national", "registry", "to", "determine", "the", "prevalence", "of", "congenital", "malformations", "at", "a", "national", "level", "." ]
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4118
[ "Hearing", "loss", "is", "one", "of", "the", "most", "common", "birth", "disorders", "in", "humans", ",", "with", "an", "estimated", "prevalence", "of", "1", "-", "3", "in", "every", "1000", "newborns", "." ]
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4119
[ "This", "study", "investigates", "the", "molecular", "etiology", "of", "a", "hearing", "loss", "cohort", "using", "a", "stepwise", "strategy", "to", "effectively", "diagnose", "patients", "and", "address", "the", "challenges", "posed", "by", "the", "genetic", "heterogeneity", "and", "variable", "mutation", "spectrum", "of", "hearing", "loss", "." ]
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4120
[ "In", "order", "to", "target", "known", "pathogenic", "variants", ",", "multiplex", "PCR", "plus", "next", "-", "generation", "sequencing", "was", "applied", "in", "the", "first", "step", ";", "patients", "which", "did", "not", "receive", "a", "diagnosis", "from", "this", "were", "further", "referred", "for", "exome", "sequencing", "." ]
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4121
[ "A", "total", "of", "92", "unrelated", "patients", "with", "nonsyndromic", "hearing", "loss", "were", "enrolled", "in", "the", "study", "." ]
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4122
[ "In", "total", ",", "64", "%", "(", "59/92", ")", "of", "the", "patients", "were", "molecularly", "diagnosed", ",", "44", "of", "them", "in", "the", "first", "step", "by", "multiplex", "PCR", "plus", "sequencing", "." ]
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4123
[ "Exome", "sequencing", "resulted", "in", "eleven", "diagnoses", "(", "23", "%", ",", "11/48", ")", "and", "four", "probable", "diagnoses", "(", "8", "%", ",", "4/48", ")", "among", "the", "48", "patients", "who", "were", "not", "diagnosed", "in", "the", "first", "step", "." ]
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4124
[ "The", "rate", "of", "secondary", "findings", "from", "exome", "sequencing", "in", "our", "cohort", "was", "3", "%", "(", "2/58", ")", "." ]
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4125
[ "This", "research", "presents", "a", "molecular", "diagnosis", "spectrum", "of", "92", "non", "-", "syndromic", "hearing", "loss", "patients", "and", "demonstrates", "the", "benefits", "of", "using", "a", "stepwise", "diagnostic", "approach", "in", "the", "genetic", "testing", "of", "nonsyndromic", "hearing", "loss", "." ]
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4126
[ "This", "study", "aimed", "to", "analyze", "the", "epidemiology", "of", "congenital", "upper", "limb", "anomalies", "(", "CULA", ")", "in", "Korea", "." ]
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4127
[ "We", "evaluated", "the", "incidence", "of", "each", "type", "of", "CULA", ",", "the", "presence", "of", "coexisting", "anomalies", "and", "the", "surgical", "treatment", "status", "in", "CULA", "patients", "." ]
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4128
[ "We", "conducted", "a", "retrospective", "cohort", "study", "of", "patients", "aged", "<", "1", "year", "between", "2007", "and", "2016", "who", "were", "registered", "with", "CULA", "in", "the", "Health", "Insurance", "Review", "and", "Assessment", "Service", "of", "Korea", "." ]
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4129
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4130
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4131
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4132
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4133
[ "In", "total", "4,776", "patients", "(", "44.6", "%", ")", "underwent", "operative", "treatment", "for", "CULA", "within", "minimum", "three", "years", "of", "the", "diagnosis", "." ]
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4134
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4135
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4136
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4137
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4138
[ "Background", "The", "evidence", "of", "an", "association", "between", "statins", "and", "amyotrophic", "lateral", "sclerosis", "(", "ALS", ")", "is", "heterogeneous", "and", "inconclusive", "." ]
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4139
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4140
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4141
[ "HRs", "were", "controlled", "for", "sex", ",", "birth", "year", ",", "calendar", "year", ",", "medically", "diagnosed", "comorbidities", ",", "and", "concomitant", "medications", "." ]
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4142
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4143
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4144
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4145
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4146
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4147
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4148
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4149
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4156
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4157
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4158
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4159
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4160
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4162
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4163
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4165
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4166
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4167
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4168
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4170
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4171
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4173
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4174
[ "Primary", "mitochondrial", "diseases", "are", "associated", "with", "genetic", "mutations", "both", "in", "nuclear", "and", "mitochondrial", "DNA", "(", "mtDNA", ")", ",", "affecting", "genes", "involved", "in", "every", "aspect", "of", "the", "organelle", "function", "." ]
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4175
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4176
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4177
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4178
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4179
[ "Identification", "of", "the", "deficiency", "is", "vital", ",", "however", ",", "because", "treatment", "can", "lead", "to", "swift", ",", "marked", "resolution", "of", "symptoms", "." ]
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4180
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4181
[ "Purpose", ":", "Cataract", "surgery", ",", "quantity", "and", "quality", ",", "is", "an", "indicator", "of", "ophthalmic", "care", "." ]
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4182
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4187
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4188
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4189
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4190
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4191
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4192
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4193
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4194
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4195
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4196
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4197
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4198
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4199
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