question
stringlengths
1
71.9k
triage
stringclasses
2 values
What does the physical examination for congenital heart disease entail?
non-urgent
i have been having chest pains for about three months now,it starts on the right side goes to the middle and the left side and in my back.I have had a doppler stress test done and ekg and blood work and they said it all turned out good.I still have the pains in my chest what could it be,I get sharp stabing pains in the middle.What could this be?
non-urgent
hello , my 6yr old daughter is getting red cheeks every evening, she never has had them untill the last two wks.she is very active all day!. it only comes on at night, she also feels hot when the red cheeks appear. she has been takeing trimethoprim 2 times daily for apprpx 7 to 10 days could this be why?
non-urgent
Hello doctor,As I have PCOD problem and also cyst, I take tablets for period. My friend suggested Kalachikai powder. I used it for 30 days continuously, but no use. How many days should I take that powder and how to overcome this problem?
non-urgent
Hi,I am 30 years of age. I am feeling tightness in the middle of my chest. Also I am having faster HR than normal. It is around 90 to 100 at resting. Also I am feeling tightness below jaws.I have consulted some docs. I had ECG twice. My ECG is normal and my Blood pressure is also 130/75.Doc says that it may be due to the Gastric problem. Please suggest what should I do?
non-urgent
A few weeks ago I had 3 teeth pulled on the upper left side, I think Im healing pretty well, however now I have been feeling like a cold sensation in my left ear it doesnt hurt just annoying. Also my right ear will all of a sudden start feeling like its poppng but its not popping just a sensation as if it is. Just wondering if maybe this had anything to do with my dental work or what?? Thank you
non-urgent
I am a 42 yr old female and my blood is 149/102. I do not suffer from high b/p, I have been experiencing right arm pain from my shoulder down to my hand for over a week now since last Tuesday and today is 9/3 and I just startred experiencing a bad headache 2 days a go.
non-urgent
The COVID-19 pandemic caused a lockdown of Wuhan, and strict control was imposed in many major Chinese cities, including the national capital of Beijing Residents? committee workers at the grass-roots level have played a critical role in the enforcement of the government?s pandemic prevention and control measures, through their day-to-day service and surveillance as local community managers This article examines their work in Wuhan and Beijing neighbourhoods during the most critical periods of the outbreak, from late January to June 2020, and the challenges the workers faced as executors of the government?s community-based prevention policy The two cities have developed different community strategies because of very different epidemiological situations and city functions
non-urgent
Hello, I was wondering if you could help me. For a long time now I have been feeling really low and helpless. Some days I am my old self, confident and bubbly but I can fall very quickly. Sometimes I cant sleep, I have headaches and I feel so incredibly lonely all the time even though I have family. I can only say to myself so many times that I am just down but this has been going on for a long time now and things that once were enjoyable are not anymore. Is this something I should go to my GP about? Is this depression of some sort?
non-urgent
About 5 or 6 years ago when I was in middle school, I had to have a root canal on one of my bottom teeth. since then I have gotten braces put on and taken off my teeth. I still have a wire on the back of my bottom teeth. I have never had an actual problem with my root canal. Recently i'm starting to feel soreness and at sometimes intense pain starting from where my lower lip and lower gum meet to the starting of the top of my chin. I hurts to put pressure on it. When i put pressure on it , it sends a pain sensation through, I guess, My nerves to one of my teeth. I was thinking it might be because the wire on the back of my lower teeth had came off but i'm starting to think otherwise. Also i thought about this new found pain to be related to my root canal i had 5 or 6 years ago, but the strange thing id that the pain sensation is going to another tooth instead of the one I had a root canal on. It also hurts when I make facial expression that involve my muscles uncle my lower lip. (example: when going to kiss). To my knowledge I have not hit this area that is sore to make it hurt.
non-urgent
while playing at playground i fell flat on my face.. and felt slight pain at my urethra. It was ok for three to four hours but after that it started to pain and now i can see slight reddish coloured urine and after-pain also. What should i do?? Please help!!
non-urgent
I've had a headcold, coupled with some sort of flu (sensitive skin, fever of 102F, lethargy) this past week and am now almost completely well, but have a pimple-like rash all over my body (not very itchy)...is this something I should be concerned about
non-urgent
A family member had a heart attack and was admitted in the hospital after several hours...because of which his valve has got damaged, the heart muscles as well as the kidney...he is diabetic. They had the stress thallium test done today and docs say only 25% heart is functioning. What do you suggest we should do now. Thanks in advance.
urgent
Hello. A week ago i strained my lower back , it was quite painfull , i took advil and rested in hot tub all weekend on monday all was good at work. Today i picked up a ladder and felt a pop In my lower back . There was pain but not as much as last time I now have noticed a click in that spot when i lift my right leg forward To waist level with knee bent down...
non-urgent
Involved field radiotherapy was tolerated reasonably well.
non-urgent
I ride bmx, and recently I fell backwards pff my bike at a decent speed. I dodnt think much of it but minutes later I started feeling pain at the bottom of my spine. It bothered me the rest of the day. The next say I rested and did minor activity and the pain lessened. I went to ride my bike again today at the skatepark and the more active I got, the more I started feeling the pain come back. Anything I can do to recover?
urgent
Could you please explain what peritoneal carcinomatosis means?
non-urgent
I have been having problems with pain in my right shoulder for several months. Sometimes I wake at night and my arms and shoulder hurts and on days I get up and it is not hurting as soon as I start having movement in it it begins to ache, especially during physical therapy even tho I am not lifting the weight nor arm. Last Monday my arm from my elbow into hand got very tired while I tried to walk on treadmill and began to ache. I only walked 3 minutes an had to quit because of my arm and hand. Friday my elbow started hurting. My Physical Therapist thinks I am having problems with the nerves in my neck causing these problems. This morning I woke up with my right hand numb and tingling and aching. It did get some better but has tingled and hurt all day (16 hrs), I have also had bouts of shortness of breathe on some days over the past couple of months which may be from stress. What type of doctor should I see to get a diagnosis? Two years ago I was having a lot of pain in this same shoulder and my surgeon who did my rotator cuff on my left shoulder talked about having an MRI done to see if he could tell what was wrong with it once my other shoulder healed, but it got better so we didn t do the MRI. This pain is different from that shoulder pain. He only does shoulder so I don t know if it would do any good to go see him. What do you suggest?
urgent
What is the mainstay of treatment for a patient diagnosed with Takayasu arteritis?
non-urgent
My seizures increased so I am trying to get back on topomax so i am taking 1 tab lam 150mg 2x daily + 1 50mg top 2x daily I was taking 2 150mg lamictal 2x daily I haven t gotten in to see a new neurologist yet since i am on medicaid now. I can t seem to even get an appt. I got these directions from my pcp but i feel strange and he told me to ask my pharmacist lol and then the pharmacist told me to take a lamictal and a full topamax and but i cant remember if he said to take the full once a day at 1st then twice a day but then he said to ask my dr.
urgent
Dosage and time of administration vary, but especially in older studies, the statin was administered between 6 and 12 h before CM.
non-urgent
My father in law is 62 years of age and suffering from a tumor in one kidney and the doctor says it needs to be operated. The problem is that he also has Hepatitic C and neuro problem with Enchaphalitis . He alsohas a thyriod of 14.5 , Pls advise if this surgery has a life risk
urgent
Hello doctor, I am 35 years male who had low-risk penetrative activity (as used condom properly and no breakage) with a female of unknown status. On the 30th day (four-week mark), I had HIV 1 and two antibodies screening test. Serum equal to HIV 1/2 by flow through immunofiltration (seems rapid test) from the reputed lab for which HIV one and two both came negative. On the 44th day (6th-week mark), I again had HIV 1, and 2 antibodies screening test, serum equal to HIV 1/2 and P24 COMBO TEST (CMIA) from the same lab and resulted non-reactive on the next day. Kindly guide am I safe or is it the end of hope for me as I am searching like crazy every hour and any abnormality like cough, pimple, uneasiness in the throat (no pain while swallowing food), etc. is being looked as a symptom of HIV. I am looking for the ray of hope.
non-urgent
I have a small lump under the skin on my temple. You can't see it you can only rub your finger across my temple and feel a small bump. I would say it is about half the size of a pea. It doesn't cause any pain. It makes me very nervous. Could it be a tumor? I've noticed it there for a month. I don't know how long it was there before then.
non-urgent
If i have a positive ovulation test, and i have sex on the same day and day after, but no sex after then, can i still be pregnant .
non-urgent
I had a root canal done a few years ago, but never got it capped. The filling held and I honestly forgot about it until one morning 90% of the tooth broke apart in my mouth. Occasionally food gets it the opening of the tooth, and I remove it, but I noticed a very small piece of "pink" came out. What damage if any can happen if the gutta percha comes out?
urgent
Hello doctor,As I have PCOD problem and also cyst, I take tablets for period. My friend suggested Kalachikai powder. I used it for 30 days continuously, but no use. How many days should I take that powder and how to overcome this problem?
non-urgent
description of case (the sicker is my daughter) problems: Cough wet often comes during the night and Little during day which has been going on month so after the examination in the first week show that white blood cells around 7000 and a competent doctor gave us medicine syrup named P.M with Cefarall syrup and used it for one week but did not improve the situation ,he changed treatment and gave us Glopidon syrup ,situation has improved a bit, then returned to previous situation ,kindly please your advice in this case and For your information the baby (daughter) 5 months old
urgent
Hello doctor,As I have PCOD problem and also cyst, I take tablets for period. My friend suggested Kalachikai powder. I used it for 30 days continuously, but no use. How many days should I take that powder and how to overcome this problem?
non-urgent
hello doctor i have been taking chance for child.i went to doctor doctor done folicular studied and then gave me preciption fist my mc period is 21 days and he gave me folvite tab then tab ccq100mg then gave me injection then dubagest200mg but i had done then i got period so what i will do?
urgent
i m 27 years old height 5.9 inch weight about 55 kg from last one year i was suffering from a home tension for that i cant sleep properly heart was felling like i going to die i smoke a hell i left my work as i lost of my baby and beging affred my heart nd brain working slow any solution
urgent
Who needs Appendectomy?
non-urgent
Hi, For months every morning when I wake up I feel sore and my back really bothers me. It lessens when I get up and around. It really feels like my muscles are sore and I ve been working out. I awaken off and on all night. Why would my muscles be sore?
non-urgent
I'm 32 yrs old I'm 5'3 I don't have any health issues. The palm of my hand, in between my fingers, and a place on my wrist started itching some and I have dried skin on my wrist aftEr It had three tiny blisters and I have tiny blisters in between my fingers. I do have diarrhea on occasions.
urgent
i have severe back pain in the left side.consulted the doctor and he asked to do a MRI.MRI report shows partial compression collapse D7 vertebra with slight anterior widging and evidence of mild marrow edema.mild dorsal disc herniation seen at D11 -12 causing ventral thecal sac impingement.Degenerative changes of spine showing variable disc dessication,marginal osteophytosis and small schmorls node in the D7 upper and lower D11 lower end-plate.while sleeping the pain increases...at times i wake up at night due to severe pain..wheareas in the morning i hv less pain while moving...the pain which i feel is in the muscles...please let me know what should i do and how do i get relief.D.C.Das70 years.maleAssam.India
urgent
I am a 25 years old 85 kgs weight 5’ 6’’ of height male having pains on left chest since last 8 months went to consult a doctor suspecting cardiac problems. But after comprehensive heart check ups it revealed that no problems are associated with heart. Uric acid raised abnormal studies have been found on liver problems.CAN I TAKE THE FOLLOWING MEDICINES?1). Metadoxil (500 mg) - 1 tab twice after food 2). Librium (10 mg) - 1 tab thrice after food 3). Nexito Forte - 1/2 tab before food 4). PAN-D - 1 tab before b/fast 5) URICOSTAT 40 MG- ONE TAB ON 9.00PM.FOLLOWING STUDIES HAVE COME OUT BY DIAGONOSIS.Weight-85 kgsHeight- 5’ 6’S. Tryglycerides(wet chem.)-155Uric acid-9.4S TOTAL BILIRUBIN: 2.90 MG/DL S DIRECT BILIRUBIN: 0.55 MG/DL S INDIRECT BILIRUBIN: 1 MG/DL S TOTAL PROTIEN: 8.4 Gm/dlS ALBUMIN : 4.5 S GLOBULIN 3.9 S A/G RATIO: 1:2:1 SGOT 109 IU/L SGPT: 198 IU/L S ALKALINE PHOSPATE: 141 SGGT : 136
non-urgent
I had a hip scope two weeks ago. I have a rash on my face that seems to be spreading only on the face. We noticed the rash appear when I got out of recovery to currently. I stopped taking any pain meds over a week ago, thinking of allergic reactions. Also no new meds started, face creams, foods, drink, drugs etc. I have had 2 MIs and am 31 years old. No allergies to anything. Any ideas?
non-urgent
Hello doctor, I have multiple small cysts in both ovaries (PCOS). Our family friend suggested me to consume Kalarchikai medicine, powdered mixed with pepper and honey to have it for one mandalam (48 days). I have completed nearly 44 days by consuming one small ball of the mixture every morning and before two weeks I got my periods. Then I had checked whether the cysts were dissolved by having an abdomen scan. But still, small multiple follicules have been seen in it with both ovaries enlarged. Kindly suggest me what I can do further. I got married before one and a half years and I am much worried about my pregnancy. I have gallstones as well.
non-urgent
The often synanthropic long-tailed macaque (Macaca fascicularis) is listed in Appendix II of CITES and was recently updated to Vulnerable on the IUCN Red List. The update was highly anticipated, as it can have wide-reaching implications for long-tailed macaque conservation and trade. Long-tailed macaques have suffered from intensive capture for biomedical research since the 1960s. From 2008-2019, at least 450,000 live long-tailed macaques, and over 700,000 "specimens" from an unknown number of individuals were part of this trade, with over 50,000 termed as wild-caught. These official trade numbers exclude laundering of wild-caught individuals as captive bred, harvesting for breeding center upkeep, their capture for the pet trade, hunting for consumption, and culling due to human-macaque conflicts. With Fooden's population estimate of 3 million long-tailed macaques in Southeast Asia in 2006, this is likely not sustainable. In some areas, they have already been extirpated because of this trade, as detected by a survey of 200 km of suitable habitat in Cambodia in 2008. Long-tailed macaques are one of the most geographically widely dispersed and adaptable primate species. However, their flexibility and preference for the forest edge draws them to anthropogenic habitats, where their visibility results in assumptions of overabundance, as was demonstrated on Java in 2009 and 2017. Long-tailed macaques face many threats, and there is an urgent need for systematic demographic and range surveys across Southeast Asia, as well as investigation into local, regional and national perceptions of long-tailed macaques. Current conservation foci should include dynamic widespread synanthropic species, such as long-tailed macaques, which are often targets of intensive trade and other threats. Insights from such studies may be critical for effective conservation and management in the 21st century. © 2021 Global Wildlife Conservation. All rights reserved.
non-urgent
Hi I am 27 weeks pregnant and I have been suffering with swollen lymph nodes in my neck. My ears and throat do hurt. I have gone to see my MD twice about this problem that has been bothering me for about a month now. They prescribed me loratidine because they said they only saw water in the ears. Today my throat really hurtsand is difficult for me to swallow. No one has done any blood work as of yet and I am growing more concerned. What should I do at this point?
urgent
Q:A 59-year-old man is brought to the emergency department by his wife for a 1-hour history of sudden behavior changes. They were having lunch together when, at 1:07 PM, he suddenly dropped his sandwich on the floor. Since then, he has been unable to use his right arm. She also reports that he is slurring his speech and dragging his right foot when he walks. Nothing like this has ever happened before. The vital signs include: pulse 95/min, blood pressure 160/90 mm Hg, and respiratory rate 14/min. The physical exam is notable for an irregularly irregular rhythm on cardiac auscultation. On neurological exam, he has a facial droop on the right half of his face but is able to elevate his eyebrows symmetrically. He has 0/5 strength in his right arm, 2/5 strength in his right leg, and reports numbness throughout the right side of his body. Angiography of the brain will most likely show a lesion in which of the following vessels?? {'A': 'Internal carotid artery', 'B': 'Anterior cerebral artery', 'C': 'Middle cerebral artery', 'D': 'Posterior cerebral artery', 'E': 'Basilar artery'},
urgent
hi,iam 25yr old.i have been trying to conceive for last 2yrs. I successfully conceived in march after taking siphene 100mg and evadiol for 3 months.But misscarried in 9th week. Now again I am taking siphene 100mg from my 2nd day. on 14th day of period i did ovulation test and i got positive result but not concieved..So, is it possible that i can get pregnant?
non-urgent
I am 26 years old.I am feeling congestion in chest frequently during winter season. I was advised by my family doctor to buy a nebuliser and use Asthalin and Budicort liquids in it. Are these mediciness safe and effective enough to get relief from chest congestion?
non-urgent
I had a c section 8 weeks ago due to placenta praevia and very risky complications. This was done by spinal epidural and i was kept awake. A week later i noticed a numbness in my right knee which didn t hurt but felt very strange. This past week the numbness has changed into feeling very tight and it is painful to walk on it particularly going up and down stairs. I do have a history of knee pin but it has always been put down to hypermobility . This tighness is like someone has wrapped a bandage around it far too tightly and it doesn t go away when sitting or standing. I was on clexane for 6 weeks following surgery and wore the TEd stockings for 2 weeks. Thanks for your helps
non-urgent
BACKGROUND To evaluate the effects of interventions on children's and adolescents' overall physical activity (PA) for boys and girls separately and to appraise the extent to which the studies haven taken sex/gender into account. METHODS Systematic review and semi-quantitative analysis. Eleven electronic databases were searched to identify all relevant randomized and non-randomized controlled trials. Studies had to report overall PA as the main outcome to be eligible for inclusion in the review. The main outcomes of the studies is a quantified measure of overall PA. Additionally, all studies had to report sex/gender disaggregated overall PA at baseline and/or follow up and/or explain how they dealt with sex/gender during outcome analysis (i.e., sex/gender adjusted analyses) and/or report that there were no differences in the outcome when looking at sex/gender. PRISMA guidelines were followed. Two authors independently screened studies for eligibility and assessed the risk of bias. Semi-quantitative analyses were conducted to evaluate intervention effects, taking into account the extent to which studies have considered sex/gender aspects. To evaluate sex/gender considerations in primary studies, a newly developed sex/gender checklist was used. The study was registered previously (registration number CRD42018109528). RESULTS In total, 97 articles reporting 94 unique studies with 164 outcomes for overall PA were included in the present review. Average sample size was 829 participants, ranging from five to 9839. Participants' ages ranged from three to 19 years. Our review shows that overall 35% of PA outcomes had significant effects in increasing overall PA of children and adolescents. Not including single sex/gender studies, 105 out of 120 PA outcomes resulted in same intervention effects for boys and girls. The interventions reported to have similar effects on PA outcomes for boys and girls showed higher quality of reporting sex/gender aspects of measurement instruments, participant flow and intervention content and materials than PA outcomes with effects only in boys or only in girls. Overall, consideration of sex/gender aspects in intervention studies is low. CONCLUSIONS There is still a need to address sufficient consideration of sex/gender aspects in developing and implementing interventions in the context of PA.
non-urgent
my mum has pancreeatic cancer for the last year she was brining up blood last night was taken in to hospital is in side room drs think that it might be her meds that have caused her to bring up blood i think its the next stage of her cancer can u help
urgent
I have a very very very large gap in my front teeth and the rest of m teeth are also spacy at the top. I have lost a about three molars and the lower teeth has some gaps as well. how can the gaps be closed especially at the top without braces. I also have protruding teeth due to tongue thrust. is there any help for me without braces.
non-urgent
My son has been around his cousin who I just found out had MRSA on the bottom of his foot. He also had a red line going from his foot to his groin. His father called me to tell me that he had a sore on his thumb from riding his dirt bike and now complaining his entire arm hurts and has a red line from his hand to his armpit.
urgent
i have problem about loose stool from two years after taking nor metrogyl i feel good for some days but loose stool not cured yet
non-urgent
I was masturbating a few moments ago and when I rolled over I managed to jab the center of my penis on the pin on my belt buckle (that goes into the holes). Though it didn t pierce the skin (blunt trauma) it certainly hurt like hell, blood started coming out of my penis. The bleeding and pain has stopped, but I m really freaked out. What exactly happened down there?
urgent
My 4 months old daughter continuously 3 weeks she have loose motion then i examined to her stool, after that mucus + and fat globules +, then doctor gave one medicine for my baby medicine name is bifilac, and septran, then doctor told me that if it is not stopped you must stop breast feeding i am very worried of this please tell what happend my baby, if it is any problem in milk?
urgent
dear dr. my 17yrs daughter is suffering from severe allergy since 3yrs. i have tried many drs. but all ae gone in vain. she is taking alaspan 10g. and it makes her drowsy. plz tell me what i should do. i am very much worried with her health, bcoz she is becoming waek day by day. she has obesity also. susmita chatterjee west bengal
non-urgent
im 29 run every week and carry no weight, ipalpatations and and an ecg it said possible right ventricle hypertrophy and right bundle branch block. i have never had pain and only pulpatations when relaxing never when excercising. any ideas or comments welcome. age 29 5foot 11 no history.
non-urgent
Hello I was having intercourse with my girlfriend and I appears I have a small cut on my frenulum. It was bleeding for a little bit but after the next day the bleeding stops and looks like it s healing it s hard to tell it there s a little pain every now and then. Can I still have intercourse with a condom or should I wait a couple weeks? I m a little concerned this is never happened I am not circumcised I haven t had this problem before
non-urgent
I am a 57 yr old Asian male who recently lost 20 lbs over 2 months thru reduced carbs, increased exercise (moderate) and increased intake of fruits and vegetables (no fad diet.) I feel great and shed excess weight (10 more to go to reach healthy weight (145) as I am 5 5 . My recent blood panel showed elevated SGOT of 50 and my MD advised me to stop losing wt. this seems illogical and I would like to continue to keep this healthy behavior regimen. Your opinion?
non-urgent
Hai doctor I am 22 year old and my husband 26 , I am suffering from pcod but I have a normal ovulation and regular periods . A detailed semen analysis of my husband shows sperm count -10millions, active motility -10%, sluggish motility 40% dead -50%, morphology 15% . according this report how much chance to get pregnant
non-urgent
Laparoscopic donor nephrectomy (LDN) has numerous advantages over open donor nephrectomy. The cosmetic issues and pain that arise due to the 5 to 6-cm incisions on the abdominal wall in LDN have led to transvaginal laparoscopic donor nephrectomy (TVLDN). Between May and August 2012, we performed seven donor nephrectomies via a transvaginal approach. The mean age of the donors was 53.0 ± 9.52 years. The mean operative time was 97.29 ± 39.47 minutes and mean warm ischemia time, 220.71 ± 55.49 seconds. Donors were mobilized, began oral intake at 8 hours postoperative, and were all discharged within the first 24 hours. Except one dose of analgesic applied immediately after the operation, no additional medication was required. No infectious complications were encountered in any recipient. TVLDN may be a good alternative for female donors. Compared with LDN, TVLDN has benefits of less postoperative pain, faster recovery, shorter hospital stay, and excellent cosmetic results.
urgent
hi, i am having a pain in my lower right abdomin suddenly. it really hurt, it felt like someone was pinching an organ. it was very sharp and sudden. it made me keel over. i am having a little dull pain afterwards. i am also experiencing indigestion, but this feels unrelated. there could be a possibility i am pregnant about 5 weeks. i have been pregnant before but have not felt this feeling before. what do you think it could be related to?
urgent
Hi, I have been on clomid from second day of my period for 5 days.Then I was given injections to induce ovulation. Once my follicle was 18mm,i was asked to ahve intercourse. Doctor said that ovulation did not occur next day and gave me HCG shot. We had intercourse on the day of shot and the next day.I had bad back pain on the day.I went to doctor next day morning and she said I had ovulated and asked me to take progesterone capsule gestofit 200 mg vaginally.I did not have intercourse the day she confirmed ovulation has occurred.But, it could have already happened on the day i had intercourse, one night before i went to doctor finally. is there possibility of my pregnancy? I had a little bit of white discharge from vagina after taking the gestofit, is that normal?
non-urgent
The three known human highly pathogenic coronaviruses are severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus, (MERS-CoV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Human highly pathogenic coronaviruses are composed of non-structural proteins, structural proteins and accessory proteins. Viral particles recognize host receptors via spike glycoprotein (S protein), enter host cells by membrane fusion, replicate in host cells through large replication-transcription complexes, and promote proliferation by interfering with and suppressing the host's immune response. Human highly pathogenic coronaviruses are hosted by humans and vertebrates. Viral particles are transmitted through droplets, contact and aerosols or likely through digestive tract, urine, eyes and other routes. This review discusses the mechanisms of proliferation and transmission of highly pathogenic human coronaviruses based on the results of existing research, providing basis for future study on interrupting the transmission and pathogenicity of human highly pathogenic coronaviruses.
non-urgent
Following the proven concept, capabilities, and limitations of detecting the RNA of Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) in wastewater, it is pertinent to understand the utility of wastewater surveillance data on various scale. In the present work, we put forward the first wastewater surveillance-based city zonation for effective COVID-19 pan-demic preparedness. A three-month data of Surveillance of Wastewater for Early Epidemic Prediction (SWEEP) was generated for the world heritage city of Ahmedabad, Gujarat, India. In this expedition, one hundred sixteen wastewater samples were analyzed to detect SARS-CoV-2 RNA, from September 3rd to November 26th, 2020. A total of 111 samples were detected with at least two out of three SARS-CoV-2 genes (N, ORF 1ab, and S). Monthly variation depicted a significant decline in all three genes copies in October compared to September 2020, followed by a sharp increment in November 2020. Correspondingly, the descending order of average genome concentration was: November (~10729 copies/ L) > September (~3047 copies/ L) > October (~454 copies/ L). Monthly variation of SARS-CoV-2 RNA in the wastewater samples may be ascribed to a decline of 19.3% in the total number of active cases in October 2020 and a rise of 1.82% in November 2020. Also, the monthly recovery rate of patients was 16.61, 19.31, and 15.58% in September, October, and Novem-ber 2020, respectively. The percentage change in the genome concentration was observed in the lead of 1-2 weeks with respect to the provisional figures of confirmed cases. SWEEP data-based city zonation was matched with the heat map of the overall COVID-19 infected population in Ahmedabad city, and month-wise effective RNA concentration variations are shown on the map. The results expound on the potential of WBE surveillance of COVID-19 as a city zonation tool that can be meaningfully interpreted, predicted, and propagated for community preparedness through advance identification of COVID-19 hotspots within a given city.
non-urgent
Hello, I was feeling very much tired and weakness. When blood was diagnosed for ANTI PLATELET ANTIBODY following results observed
non-urgent
Hi, I've just returned from Thailand and Vietnam and have a nasty red blotchy rash on my feet and ankles. I wasn't bitten but have had this for around a week now. On the flight home, both my ankles swelled considerably. Is this anything to worry about?
urgent
dr,iam suffering lot of problem from depression .ihave consulting two doctors for this.one suggest d-axid tablet..and another doctor suggest nexito plus and lonazep m.d .which medicine is better for my problem.This medicine is continuosly used for a long time for my disesse is completely curable..please suggest a suitable remedy.
non-urgent
Hi, I am 40 year old female and have been experiencing alot of pain on the right middle portion from the top of my thigh just at the crease of my gluteous max. I sit for a short period of time and can not apply any pressure to that area and the same when I lay down, I can not lie on the right side at all and when I turn to lay on my stomach alot of throbbing pain is under my gluteous at the crease very painful . This has been going on when I had a problem with my sciatic nerve on both sides but the right side still hasn t ceased in this localized area. I try to soak in warm water and massaged and it still does not bring relief. Any ideas. TY
non-urgent
Hi doctor, My mom was admitted to the hospital due to an extreme headache, clicking sound in the head and high blood pressure. CAT scan revealed that she had a benign brain tumor and no surgery will probably be needed. After making an MRI, another neurosurgeon said she would have to remove it as it could lead to blindness and difficulty talking and moving. After contacting another neurosurgeon for advice he said no surgery is needed. I would appreciate if you could take a look at the MRI images and give me advice because they are already preparing her for the surgery this week and I am not even sure if it is necessary. Thank you.
non-urgent
Who is at highest risk for Impacted tooth ?
non-urgent
Hello, I had 2 root canals done in the past month in a half. First was Upper back left tooth and then the one second next to it. My left side of my face and temple were pounding as well as the tooth, along with pressure...this was after my second tooth.. dentist opened it back up and let it breath, then retreated. All was well for 2 weeks. Now face pain and throbbing are back but now it is the tooth with first root canal that feels pressure and throbs. Could this be another failed root canal and could this be why the side of my face is throbbing? I also have not been feeling well since this all started..such as lathargic and mild sore throat ...as well as metalic taste that seems to only be on left side of my tongue . Thank you. Paula
non-urgent
Im 32, 6 1 , 160 lbs. Ttc, went off pill about 2 months ago. I started bleeding 3 days before I was supposed to get my period. It was pretty light but a little more.than spotting. It only lasted about a day and a half. Then a day later I started bleeding again. This time it was a little heavier but still not as heavy as my normal period. It lasted about a day and a half and has now stopped. Home hpt test.was negative. Any advice as to whats going on?
non-urgent
This paper describes a hands-on comparison on using state-of-the-art music source separation deep neural networks (DNNs) before and after task-specific fine-tuning for separating speech content from non-speech content in broadcast audio (i.e., dialog separation). The music separation models are selected as they share the number of channels (2) and sampling rate (44.1 kHz or higher) with the considered broadcast content, and vocals separation in music is considered as a parallel for dialog separation in the target application domain. These similarities are assumed to enable transfer learning between the tasks. Three models pre-trained on music (Open-Unmix, Spleeter, and Conv-TasNet) are considered in the experiments, and fine-tuned with real broadcast data. The performance of the models is evaluated before and after fine-tuning with computational evaluation metrics (SI-SIRi, SI-SDRi, 2f-model), as well as with a listening test simulating an application where the non-speech signal is partially attenuated, e.g., for better speech intelligibility. The evaluations include two reference systems specifically developed for dialog separation. The results indicate that pre-trained music source separation models can be used for dialog separation to some degree, and that they benefit from the fine-tuning, reaching a performance close to task-specific solutions.
non-urgent
Mesenchymal stem cells (MSCs), due to their multi-directional differentiation, paracrine and immunomodulation potentials, and the capacity of homing to target organ, have been reported to facilitate regeneration and repair of kidney and improve kidney function in acute or chronic kidney injury. The present study was aimed to evaluate whether MSCs could have a protective effect in hyperuricemic nephropathy (HN) and the underlying mechanisms. A rat HN model was established by oral administration of a mixture of potassium oxonate (PO, 1.5 g/kg) and adenine (Ad, 50 mg/kg) daily for 4 weeks. For MSCs treatment, MSCs (3 × 106 cells/kg per week) were injected via tail vein from the 2nd week for 3 times. The results showed that along with the elevated uric acid (UA) in HN rats, creatinine (CREA), blood urea nitrogen (BUN), microalbuminuria (MAU) and 24-hour urinary protein levels were significantly increased comparing with the normal control rats, while decreased after MSCs treatment. Moreover, the mRNA levels of inflammation and fibrosis-related gene were reduced in UA + MSCs group. Consistently, hematoxylin-eosin (HE) staining results showed the destruction of kidney structure and fibrosis were significantly alleviated after MSCs administration. Similarly, in vitro, NRK-52Es cells were treated with high concentration UA (10 mg/dL) in the presence of MSCs, and we found that MSCs co-culture could inhibited UA-induced cell injury, characterized as improvement of cell viability and proliferation, inhibition of apoptosis, inflammation, and fibrosis. Collectively, MSCs treatment could effectively attenuate UA-induced renal injury, and thus it might be a potential therapy to hyperuricemia-related renal diseases.
non-urgent
hi sir ,this is suman kumar ,male ,30 from hyd .i had cough and breathing prob on jan 26 and joined a hospital in mumbai immediately ,after docs told me that i have cavities outside left lung and adviced for ct-scan. i returned to hyd and joined and multi speciality hospital .ICT procedure was done and tube was inserted on 2 nd feb.Aprrox. 700 ml of pus,waste blood was collected within 12 days and ict was removed after 2 weeks when ct was done again ,docs told me that a solid pus form was on my lung and shd peeled off.first they want to go for thoracic procedure(laproscopic kind) but today they advised me to go for open surgery . iam walking well ,breathing wll and doing normal day to day jobas well, ESR is 92 ans all bloood parameters are good. My questions is whether to go for surgey or there is any alternative for ths
urgent
Who is at highest risk for Tonsilitis ?
non-urgent
Background: Impressive progress in reducing malaria trends combined with the 2018 report of no malaria related deaths for the first time, puts Cambodia well on track to reaching its malaria elimination goals. However, the novel coronavirus SARS-CoV-2 (COVID-19) pandemic presents a potential challenge to this goal. The path towards malaria elimination is dependent on sustained interventions to prevent rapid resurgence, which can quickly set back any gains achieved. Methods Mobile Malaria Workers (MMWs) need to have a strong understanding of the local geography and, most importantly, build and maintain trust among the communities they serve. To achieve this, Malaria Consortium uses a peer-to-peer approach for the MMWs and ensures the same level of trust operates between the MMWs and Malaria Consortium. Malaria Consortium’s policy during COVID-19 has been to follow national guidelines while continuing to support community-based malaria services via the MMWs / mobile malaria posts (MPs) with as minimal disruption as possible. A risk assessment was carried out by Malaria Consortium, with a mitigation plan quickly developed and implemented, to ensure MMWs were able to continue providing services without putting themselves or their patients at risk. Results Malaria Consortium ensured the MMW/ mobile MP program is built on trust, relevance to, and connection with the communities being served. An overall decline in malaria testing was reported from Health Centres and VMWs among all three provinces in March and April, not seen in previous years and possibly attributable to fear of COVID-19. However, Malaria Consortium supported MMWs have not reported any such decline in the utilization of their services and attribute this to the trust they have among the communities. Conclusion Malaria Consortium has effectively demonstrated care and solidarity with and among the MMWs and communities being served. This has ensured a high level of trust, and therefore willingness among the MMWs and communities to continue providing and utilising malaria services as usual despite the fear of COVID-19. Building trust among rural communities builds resilience and ensures uninterrupted and effective malaria elimination activities can continue even during a potential extraneous disruptive force, such as the Covid-19 pandemic.
non-urgent
My abdominal USG concludes GRADI I Prostatomegaly and mild Hepatomegaly with fatty infiltration. Am diabetic and hypertension patient. Am on 1000 mg Metformin, AMTAS HT, Ecosprin 75 mg, PROLOMET XL 50 mg and ATACOR 20 mg a day. I exercise at least three days in a week. My height is 5 ft 7 inches and am weighing 82 Kg. Would you please explain what is the meaning and explain the reasons which could contribute to these conditions.
non-urgent
HI Doctor, My Recent Blood Report Says 1. ALKALINE PHOSPHATASE PHOTOMETRY - 99.4 U/l 2. BILIRUBIN -DIRECT PHOTOMETRY - 0.17 mg/dl 3. BILIRUBIN - TOTAL PHOTOMETRY - 0.54 mg/dl 4. BILIRUBIN (INDIRECT) CALCULATED - 0.37 mg/dl 5. GAMMA GLUTAMYL TRANSFERASE (GGT) PHOTOMETRY - 61.1 U/l 6. ASPARTATE AMINOTRANSFERASE (SGOT ) PHOTOMETRY - 34 U/l 7. ALANINE TRANSAMINASE (SGPT) PHOTOMETRY - 68.2 U/l 8. PROTEIN - TOTAL PHOTOMETRY - 7.02 gm/dl 9. ALBUMIN - SERUM PHOTOMETRY - 4.46 gm/dl 10. SERUM GLOBULIN PHOTOMETRY - 2.56 gm/dL 11. SERUM ALBUMIN/GLOBULIN RATIO CALCULATED - 1.74 Ratio 12. TOTAL CHOLESTEROL PHOTOMETRY 212 mg% 13. HDL CHOLESTEROL - DIRECT PHOTOMETRY 27 mg% 14. LDL CHOLESTEROL - DIRECT PHOTOMETRY 146 mg% 15. TRIGLYCERIDES PHOTOMETRY 227 mg% I am of 38 years old, male and non diabetic and non alcoholic. I do not smoke. Suffering with mild abdominal pain from 2 months. Is there any co-relation between the Cholesterol levels and Liver functional tests and abdominal pain.. Kindly suggest appropriate diet and any important suggestions.
non-urgent
hi i am having sharp pains in my stomach, i wake up during the night with them . i also feel sick in the mornings and i have to lay still for the sickness feeling to go. i visited my gp yesterday and they told me to do a water sample she then told me i had a water infection she prosribed me with some antibiotics called trimethoprim can you think of anything eles it may be?
non-urgent
What is the main characteristic of obstructive sleep apnea during sleep?
non-urgent
Hi, I just got my blood work back and my alt was up to165 (from 33) my ast was up to 63 (from 48). My last tests were 11-10- 2013. I am a 45 year old female and am concerned about the sharp increase. I do not drink very much but I do take several prescription medications. Also my alkaline phosphatase went up to 164 (from 90 in Nov 2013). The only other significant change is saw was my platelet dropped. They were 344 on 11-10-13 and now they are 194. They have never been below 300. I d appreciate any insight. Thanks, Pam
urgent
I got an inflated gum,dentist took me an x ray,he told me to pull out my tooth so that the infection would heal,cos if i take a course of antibiotics will work for only few days and the inflated gum will return.Do I have to loose a tooth to heal the inflated gum? thx for your answer.
non-urgent
Recent increases in marijuana use and legalization without adequate knowledge of the risks necessitate the characterization of the billions of nanoparticles contained in each puff of smoke. Tobacco smoke offers a benchmark given that it has been extensively studied. Tobacco and marijuana smoke particles are quantitatively similar in volatility, shape, density and number concentration, albeit with differences in size, total mass and chemical composition. Particles from marijuana smoke are on average 29% larger in mobility diameter than particles from tobacco smoke and contain 3.4× more total mass. New measurements of semi-volatile fractions determine over 97% of the mass and volume of the particles from either smoke source are comprised of semi-volatile compounds. For tobacco and marijuana smoke, respectively, 4350 and 2575 different compounds are detected, of which, 670 and 536 (231 in common) are tentatively identified, and of these, 173 and 110 different compounds (69 in common) are known to cause negative health effects through carcinogenic, mutagenic, teratogenic, or other toxic mechanisms. This study demonstrates striking similarities between marijuana and tobacco smoke in terms of their physical and chemical properties.
non-urgent
Hi doctor i have some questions, now i am in seven weeks 4 datys pregent,my early scan pelvic scan reports show ing below items. could you please check , how is my baby growth .gravid uterus.c.r.l = 1.3 cm correspoding 7 weeks + 4 daysyolk sac: presentFetal pole : presentfetal heart pulsation : presendecidual reaction : presentboth adnexae: normalcervical length : 3.5internal os is closed
non-urgent
Hello doctor, My fiancee and I had unprotected sex a few days back, but I did not ejaculate inside her. Just to be on the safer side, we wanted to use the emergency contraceptive pill. But due to some restriction in the country where we live, Plan B or emergency contraceptive pills are not available. I read that Yasmin, which is used as a regular contraceptive pill can be used as an emergency contraceptive pill at a higher dosage. Can Yasmin be used as an emergency contraceptive pill? And at what dosage?
urgent
In the present disorder, however, the stimulation-dependent decrement of the CMAP is not owing to impaired resynthesis of acetylcholine and concomitant abnormal decrease of the EPP, but stems from a defect in Nav1.4.
non-urgent
The objective of the research was to identify the factors that contribute to the increase in rates of gender-based violence and to clarify the role of the authorities in the fight against this problem. To achieve this objective, the following methods were used: statistical analysis, hypothetical-deductive model, factor analysis, generalization and analogy and correlation analysis. It was found that there is a negative relationship between the level of violence against women and the economic situation, the level of gender inequality, the level of development of social norms and the level of gender development (only for violence against women who are not intimate partners). A positive relationship between the level of gender development and the level of domestic violence was demonstrated. Factors that directly negatively affected rates of gender-based violence were identified: cultural, traditional, religious beliefs about the status of women in society;authorities' restrictions on the rights of individuals associated with the COVID-19 pandemic. The authorities' tools to counter gender-based violence were identified. The perspective of further research is the identification of the social and legal aspects of this global phenomenon.
non-urgent
What can cause dull kidney pain?
non-urgent
my brother s daughter is 6 months old. she had watery diarrhea for 5 days then regular stool but often. nearly 10 to 15 times a day. urine culture was taken, which shows as organism found is e.coli and colony count is 80000. wat is the diagnosis? and how it can be treated
non-urgent
I have a large brown colored skin tag in groin area. When not large it shrinks down to two like pcs.?? It some time gets larger and has pussed before and it does have fowl odor sometimes. I have been putting babay powder in morning which seems to keep it from smelling. its not swallon now.should it be removed.
non-urgent
I had protective sex but the condom burst from about six days now can i take a pregancy test at any time or i have to use my first morning urine.
non-urgent
Q:Lewin’s force field theory describes planned change in organizations as involving which of the following stages?? A:unfreezing, changing, and refreezing;B:forming, performing, and re-forming;C:identifying, planning, and acting;D:setting the stage, problem-solving, and reaching an agreement
non-urgent
I have had two back operations one on the T the other on the L .i have d.d.d. My back has two compression fractures T & L .My arms are numb and my hands have very little feeling.When I wash the dish's my L really hurts so I just try and move around.My doctor gives me 10 mg of oxycodone 3 times a day and 10 mg grams of valium 2 times a day.I am 57 years old.I do not sleep good at night because of the pain.I also substitute with Naproxin sodium and Goody powders. how is Cymbalta going to help me which he just prescribe to me 30mg.
non-urgent
Hi doctor, I met with a car accident three weeks ago. I was injured and had trauma to the chest wall muscles. My chest muscles went into spasm periodically, but has subsided somewhat. My right side lower chest is the only area still hurting. After rest for a long period or sleep, when I activate the muscles in that area I have cramps. My question is, will chiropractic service help alleviate the pain?
non-urgent
mr prakash rai had been admitted in the cmc hospital unit neph 1 ward no. A/W114B hospital no. 932669D since may 25 , 2011 to 15 june he was totally fine and he was dischange by the Dr shibu jacob and he has given the medicines for 3 months also but continueing the medicine & following renal diets the same promblem accured since yesturday
urgent
OBJECTIVES: The COVID-19 pandemic has been a significant stressor worldwide and reports of psychological distress, depression, sedentary lifestyles, and overall decreased wellbeing are increasing. Yoga practices have been found to improve mental and physical health. The purpose of this randomized controlled trial is to compare Isha yoga practitioners to controls on perceived stress, resilience, wellbeing, and protection and recovery from COVID-19. Trial Design. In this prospective randomized control trial, the effects of yoga practices are being compared between seasoned yoga practitioners with two controls who are age (±3 years), gender matched, and living in the same neighborhood. METHODS: Participants will be asked to complete a series of web-based surveys at baseline, six weeks, and 12 weeks. These surveys include validated scales and objective questions on COVID-19 infection and medical history. The validated questionnaires assess stress, mood states, resilience, and overall wellbeing. Questionnaires, weekly activity diaries, and medical history, will be collected using REDCap. RESULTS: We hypothesize that routine yoga practice during the COVID-19 pandemic will reduce stress, enhance well-being, and provide protective effects against COVID-19. CONCLUSION: With the growing concern about the physical and mental impacts of COVID-19 and increased interest in alternative practices such as yogic practices, this study will contribute to the growing body of evidence about the safety and efficacy of yoga for emotional, mental, and physical health conditions.
non-urgent
Hi, I am 39 years old and after having an MRI scan, it was confirmed that I have a 4mm tumour in my pituitary gland. I have been taking quinagolide (75mg daily) since Dec 2010. My prolactine levels have returned to completely normal and I have now had my 6th period, which is great news as I am trying to get pregnant. I have since lost 3.5 stone in weight to help this process and improve my overall fitness. In the past 3 weeks, my finger tips have gone numb (including thumb and pinkie finger) 3 times. This starts in my left hand, then shortly goes to my right hand. It lasts for between half an hour to couple of hours at a time. I have an appointment with my consultant in a few months time for a 'check up', but am concerned about this numbness (with pins and needles sensation). Is this connected with either the tumour or the drugs and shall I try and get an appointment set up for an earlier date? Any advise would be greatly received. Kind regards Michele
non-urgent
I have been having abdominal pains for almost 3 weeks. I have been eating healthy my whole life I am 43. I sometimes am constipated and somtimes not. When I am not I notice a lot of air and a solid stool. I wonder if this is due to not enough water. This is the first time I ever had this.
urgent
hi doctor i got low back pain i dont know wheater its spinal problem or what bt i feel myarms and leg so weak , anxiety and sometimes chest bones , myboth arms get sharp pain or legs.. last time i got numbness but went to acupuncture numbness no more. any problem in me?
urgent
Hello doctor, In mid-February 2011, had pacemaker/defibrillator placement for low EF @ 35% and irregular beats. For about two weeks I have had intermittent heart pain and pain on my left side at the level of the heart/breast. These pains do not occur at the same time. Could it be the device is lightly shocking? The pains almost feel like spasming. Heart rate and pulse are a.o.k. I am 57 year old female, 5 7 and weigh 175
urgent
my son is 3years and 10months old,his been having fever on and off for the last 5 days.it first started with him being cold and shivering.we have been giving him nurofen every time he has a fever.he usually gets it at night.in the beginning his temperature was 103 -104,now its 101 - 102.he seem to have no other symptoms and becomes active once fever is down.his not eating much but drinking more.
non-urgent
Hi, I m a 29 yr old female in good health, I am a smoker. I ve had a pea sized lump just under skin in right armpit for 3-4 wks. Skin color has not changed, not painful, is hard & doesn t seem to move. Also been sufferind debilitating headaches, any thoughts?
urgent