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22,704,725 | 2013-04-16 | 2012-08-03 | 1878-3511 | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | The tetravalent meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine is immunogenic with a clinically acceptable safety profile in subjects previously vaccinated with a tetravalent polysaccharide vaccine. | Dbaibo Ghassan, Van der Wielen Marie, Reda Mariam, Medlej Fouad, Tabet Carelle, Boutriau Dominique, Sumbul Anne, Anis Sameh, Miller Jacqueline M | eng | null | Clinical Trial, Phase II, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't | Antibodies, Bacterial, Immunotoxins, Meningococcal Vaccines, Polysaccharides, Bacterial, Tetanus Toxoid, Vaccines, Conjugate, tetravalent meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine | IM | 22704725, S1201-9712(12)00134-8, 10.1016/j.ijid.2012.04.006 | The immunogenicity and safety of the tetravalent meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine (MenACWY-TT) were evaluated in subjects previously vaccinated with a tetravalent meningococcal polysaccharide vaccine and in subjects without previous meningococcal vaccination. | Adolescent, Adult, Antibodies, Bacterial, Child, Child, Preschool, Female, Humans, Immunization, Secondary, Immunotoxins, Male, Meningitis, Meningococcal, Meningococcal Vaccines, Neisseria meningitidis, Polysaccharides, Bacterial, Tetanus Toxoid, Vaccines, Conjugate, Young Adult | null |
22,704,726 | 2013-02-04 | 2012-09-24 | 1878-3511 | International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases | Vesico-pustular blastomycosis. | Khakoo Rashida, Roidad Nasira | eng | null | Case Reports, Journal Article | Antifungal Agents | IM | 22704726, S1201-9712(12)00131-2, 10.1016/j.ijid.2012.04.003 | null | Aged, Antifungal Agents, Blastomyces, Blastomycosis, Dermatomycoses, Fatal Outcome, Female, Humans | null |
22,704,728 | 2013-03-06 | 2018-12-02 | 1873-7560 | European urology | What do we really know about antimuscarinic therapy for adult neurogenic detrusor overactivity? | Chapple Christopher R | eng | null | Editorial, Comment | Cholinergic Antagonists | IM | 22704728, S0302-2838(12)00688-4, 10.1016/j.eururo.2012.05.069 | null | Cholinergic Antagonists, Humans, Urinary Bladder, Urinary Bladder, Neurogenic, Urinary Bladder, Overactive | null |
22,704,730 | 2013-02-08 | 2022-04-10 | 1873-7560 | European urology | Laparoendoscopic single-site nephrectomy compared with conventional laparoscopic nephrectomy: a systematic review and meta-analysis of comparative studies. | Fan Xinxiang, Lin Tianxin, Xu Kewei, Yin Zi, Huang Hai, Dong Wen, Huang Jian | eng | null | Comparative Study, Journal Article, Meta-Analysis, Review, Systematic Review | Analgesics, Creatinine | IM | 22704730, S0302-2838(12)00639-2, 10.1016/j.eururo.2012.05.055 | Laparoendoscopic single-site (LESS) surgery has increasingly been used to perform radical, partial, simple, or donor nephrectomy to reduce the morbidity and scarring associated with surgical intervention. Studies comparing LESS nephrectomy (LESS-N) and conventional laparoscopic nephrectomy (CL-N) have reported conflicting results. | Analgesics, Creatinine, Female, Humans, Laparoscopy, Length of Stay, Male, Nephrectomy, Operative Time, Pain, Postoperative, Patient Satisfaction, Postoperative Complications, Randomized Controlled Trials as Topic, Treatment Outcome, Warm Ischemia | null |
22,704,727 | 2013-07-16 | 2022-03-21 | 1873-7560 | European urology | Infective complications after prostate biopsy: outcome of the Global Prevalence Study of Infections in Urology (GPIU) 2010 and 2011, a prospective multinational multicentre prostate biopsy study. | Wagenlehner Florian M E, van Oostrum Edgar, Tenke Peter, Tandogdu Zafer, Çek Mete, Grabe Magnus, Wullt Björn, Pickard Robert, Naber Kurt G, Pilatz Adrian, Weidner Wolfgang, Bjerklund-Johansen Truls E | eng | null | Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't | Anti-Bacterial Agents, Fluoroquinolones | IM | 22704727, S0302-2838(12)00694-X, 10.1016/j.eururo.2012.06.003 | Infection is a serious adverse effect of prostate biopsy (P-Bx), and recent reports suggest an increasing incidence. | Adult, Aged, Aged, 80 and over, Anti-Bacterial Agents, Biopsy, Drug Resistance, Fluoroquinolones, Humans, Incidence, Internationality, Male, Middle Aged, Prevalence, Prospective Studies, Prostate, Prostatic Neoplasms, Risk Factors, Urinary Tract Infections | null |
22,704,731 | 2013-03-12 | 2012-10-16 | 1520-4898 | Accounts of chemical research | Direct comparison of kinetic and thermodynamic influences on gold nanomorphology. | Barnard Amanda S | eng | null | Journal Article | null | null | 22704731, 10.1021/ar3000184 | Under a given set of conditions, nanomaterials can crystallize into structures that are entirely inconsistent with the bulk material and may adopt a range of faceted morphologies that depend on the particle size. A size-dependent phase diagram, a graphical representation of the chemical equilibrium, offers a convenient way to describe this relationship among the size, morphology, and thermodynamic environment. Although creating such a diagram from conventional experiments is extremely challenging (and costly), theory and simulation allow us to use virtual experiments to control the temperature, pressure, size, structure and composition independently. Although the stability and morphology of gold nanoparticles has been add-ressed numerous times in recent years, a critical examination of the literature reveals a number of glaring contradictions. Typically gold nanoparticles present as multiply-twinned structures, such as icosahedra and decahedra, or faceted monocrystalline (fcc) shapes, such as truncated octahedra and cuboctahedra. All of these shapes are dominated by various fractions of {111} and {100} facets, which have different surface atom densities, electronic structure, bonding, chemical reactivities, and thermodynamic properties. Although many of the computational (and theoretical) studies agree on the energetic order of the different motifs and shapes, they do not necessarily agree with experimental observations. When discrepancies arise between experimental observations and thermodynamic modeling, they are often attributed to kinetics. But only recently could researchers analytically compare the kinetics and thermodynamics of faceted nanoparticles. In this Account, we follow a theoretical study of the size, shape, and structure of nanogold. We systematically explore why certain shapes are expected at different sizes and (more importantly) why others are actually observed. Icosahedra are only thermodynamically preferred at small sizes, but we find that they are the most frequently observed structures at larger sizes because they are kinetically stable (and coarsen more rapidly). In contrast, although the phase diagram correctly predicts that other motifs will emerge at larger sizes, it overestimates the frequency of those observations. These results suggest either a competition or collaboration between the kinetic and thermodynamic influences. We can understand this interaction between influences if we consider the change in shape and the change in size over time. We then use the outputs of the kinetic model as inputs for the thermodynamic model to plot the thermodynamic stability as a function of time. This comparison confirms that decahedra emerge through a combination of kinetics and thermodynamics, and that the fcc shapes are repressed due to an energetic penalty associated with the significant departure from the thermodynamically preferred shape. The infrequent observation of the fcc structures is governed by thermodynamics alone. | null | null |
22,704,732 | 2013-01-24 | 2022-03-09 | 1878-108X | Trends in neurosciences | Cell fate determination in the vertebrate retina. | Bassett Erin A, Wallace Valerie A | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22704732, S0166-2236(12)00087-2, 10.1016/j.tins.2012.05.004 | The vertebrate retina is a well-characterized and tractable model for studying neurogenesis. Retinal neurons and glia are generated in a conserved sequence from a pool of multipotent progenitor cells, and numerous cell fate determinants for the different classes of retinal cell types have been identified. Here, we summarize several recent developments in the field that have advanced understanding of the regulation of multipotentiality and temporal competence of progenitors. We also discuss recent insights into the relative influence of lineage-based versus stochastic modes of cell fate determination. Enhancing and integrating knowledge of the molecular and genetic machinery underlying retinal development is critically important for understanding not only normal developmental mechanisms, but also therapeutic interventions aimed at restoring vision loss. | Animals, Cell Differentiation, Humans, Multipotent Stem Cells, Neurogenesis, Retinal Neurons | null |
22,704,733 | 2012-12-07 | 2021-10-21 | 1475-2875 | Malaria journal | Evaluation of the rapid diagnostic test CareStart pLDH Malaria (Pf-pLDH/pan-pLDH) for the diagnosis of malaria in a reference setting. | Heutmekers Marloes, Gillet Philippe, Maltha Jessica, Scheirlinck Annelies, Cnops Lieselotte, Bottieau Emmanuel, Van Esbroeck Marjan, Jacobs Jan | eng | null | Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't | Antigens, Protozoan, L-Lactate Dehydrogenase | IM | 22704733, 1475-2875-11-204, 10.1186/1475-2875-11-204, PMC3464813, 19948018, 21676264, 15897534, 21806821, 19019399, 20092620, 20718798, 20111602, 20232100, 21314992, 18202438, 20565816, 19996417, 17360871, 12461593, 21226920, 19860920, 14515429, 19519915, 21144034, 17212967, 19416497 | The present study evaluated CareStart pLDH Malaria, a three-band rapid diagnostic test detecting Plasmodium falciparum-specific parasite lactate dehydrogenase (Pf-pLDH) and pan Plasmodium-specific pLDH (pan-pLDH) in a reference setting. | Adolescent, Adult, Aged, Antigens, Protozoan, Child, Child, Preschool, Diagnostic Tests, Routine, Female, Humans, Immunoassay, Infant, L-Lactate Dehydrogenase, Malaria, Male, Middle Aged, Plasmodium, Sensitivity and Specificity, Young Adult | null |
22,704,734 | 2012-10-02 | 2018-12-01 | 1878-1810 | Translational research : the journal of laboratory and clinical medicine | Re: Serum level of soluble CD26/dipeptidyl peptidase-4 (DPP-4). | Aso Yoshimasa | eng | null | Letter, Comment | Dipeptidyl-Peptidase IV Inhibitors, Hypoglycemic Agents, Pyrazines, Triazoles, Dipeptidyl Peptidase 4 | IM | 22704734, S1931-5244(12)00023-0, 10.1016/j.trsl.2012.01.017 | null | Diabetes Mellitus, Type 2, Dipeptidyl Peptidase 4, Dipeptidyl-Peptidase IV Inhibitors, Female, Humans, Hypoglycemic Agents, Male, Pyrazines, Triazoles | null |
22,704,735 | 2013-05-30 | 2013-01-04 | 1527-3296 | American journal of infection control | Costs of postexposure management of occupational sharps injuries in health care workers in the Republic of Korea. | Oh Hyang Soon, Yoon Chang Sung Won, Choi Jeong Sil, Park Eun Suk, Jin Hye Young | eng | null | Journal Article | null | IM | 22704735, S0196-6553(12)00177-0, 10.1016/j.ajic.2012.01.030 | Costs of postexposure treatment of sharps injuries (SIs) in health care workers (HCWs) are an economic burden in many countries. This study analyzed the costs associated with SIs in HCWs in the Republic of Korea. | Health Care Costs, Health Personnel, Humans, Needlestick Injuries, Post-Exposure Prophylaxis, Republic of Korea | null |
22,704,736 | 2013-05-30 | 2019-12-10 | 1527-3296 | American journal of infection control | Development and validation of tools for assessing use of personal protective equipment in health care. | Williams Camille K, Carnahan Heather | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Validation Study | null | IM | 22704736, S0196-6553(12)00174-5, 10.1016/j.ajic.2012.01.027 | Incorrect use of personal protective equipment (PPE) may lead to the spread of infectious agents among health care workers and patients. Although novel education programs show promise, there is no standard evaluation for the competencies developed during training. | Cross Infection, Delivery of Health Care, Education, Medical, Health Services Research, Human Development, Humans, Professional Competence, Protective Devices | null |
22,704,737 | 2012-11-08 | 2021-10-21 | 0392-856X | Clinical and experimental rheumatology | Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor. | Churchman Sarah M, Geiler Janina, Parmar Rekha, Horner Elizabeth A, Church Leigh D, Emery Paul, Buch Maya H, McDermott Michael F, Ponchel Frederique | eng | 18475 (Arthritis Research UK, United Kingdom); 18475 (Versus Arthritis, United Kingdom) | Controlled Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't, Validation Study | Biomarkers, Cytokines, Rheumatoid Factor | IM | 22704737, 5235 | Accurately measuring cytokines in clinical material remains an important challenge in the development of biomarkers. Enzyme-linked immunoabsorbent assays (ELISAs) are considered 'gold standard'; however, their use is limited by the relatively large sample volume required for multiple analyte testing. Several alternatives (including membrane or bead-ELISA) have been developed particularly to enable multiplexing. Concerns were raised regarding their use in rheumatology due to interference by heterophilic antibodies, notably rheumatoid factor (RF). In this report, we compared several multiplex assays using serum from rheumatoid arthritis (RA) patients with respect to the presence of residual RF following attempted removal employing commonly used procedures. | Arthritis, Rheumatoid, Biomarkers, Cytokines, Enzyme-Linked Immunosorbent Assay, False Positive Reactions, Humans, Microspheres, Reference Standards, Reproducibility of Results, Rheumatoid Factor, Sensitivity and Specificity | null |
22,704,738 | 2013-02-07 | 2021-12-03 | 1873-264X | Journal of pharmaceutical and biomedical analysis | The membrane permeability of Astragali Radix-derived formononetin and calycosin is increased by Angelicae Sinensis Radix in Caco-2 cells: a synergistic action of an ancient herbal decoction Danggui Buxue Tang. | Zheng Ken Yu-zhong, Choi Roy Chi-yan, Guo Ava Jiang-yang, Bi Cathy Wen-chuan, Zhu Kevin Yue, Du Crystal Ying-qing, Zhang Zhen-Xia, Lau David Tai-wai, Dong Tina Ting-xia, Tsim Karl Wah-keung | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Coumaric Acids, Drugs, Chinese Herbal, Isoflavones, danggui buxue decoction, 7,3'-dihydroxy-4'-methoxyisoflavone, formononetin, ferulic acid, angelicae sinensis extract | IM | 22704738, S0731-7085(12)00274-9, 10.1016/j.jpba.2012.05.018 | Danggui Buxue Tang (DBT), a herbal decoction contains Astragali Radix (AR) and Angelicae Sinensis Radix (ASR), has been used as a health food supplement in treating menopausal irregularity in women for more than 800 years in China. Several lines of evidence indicate that the synergistic actions of AR and ASR in this herbal decoction leading to a better pharmacological effect of DBT. Here, the role of different herbs in directing the transport of active ingredients of DBT was determined. A validated RRLC-QQQ-MS/MS method was applied to determinate the permeability of ingredients across the Caco-2 cell monolayer. AR-derived chemicals, including astragaloside IV, calycosin and formononetin, as well as ASR-derived chemicals, including ferulic acid and ligustilide, were determined by RRLC-QQQ-MS/MS. The pharmacokinetic results showed that the membrane permeabilities of calycosin and formononetin, two of the major flavonoids in AR, could be markedly increased in the presence of ASR extract: this induction effect could be mediated by ferulic acid deriving from ASR. In contrast, the extract of AR showed no effect on the chemical permeability. The current results suggested that the ingredients of ASR (such as ferulic acid) could enhance the membrane permeability of AR-derived formononetin and calycosin in cultured Caco-2 cells. The possibility of herb-drug synergy within DBT was proposed here. | Angelica sinensis, Caco-2 Cells, Chromatography, Liquid, Coumaric Acids, Drug Synergism, Drugs, Chinese Herbal, Humans, Intestinal Absorption, Intestinal Mucosa, Isoflavones, Permeability, Spectrometry, Mass, Electrospray Ionization, Tandem Mass Spectrometry, Time Factors | null |
22,704,739 | 2012-10-16 | 2012-06-18 | 1873-2607 | American journal of preventive medicine | Motorized transportation, social status, and adiposity: the China Health and Nutrition Survey. | Qin Li, Stolk Ronald P, Corpeleijn Eva | eng | DK056350 (NIDDK NIH HHS, United States); R01-HD30880 (NICHD NIH HHS, United States); R01-HD38700 (NICHD NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | null | IM | 22704739, S0749-3797(12)00254-1, 10.1016/j.amepre.2012.03.022 | Increased dependence on motorized transportation may contribute to obesity. Countries in rapid socioeconomic transitions, such as China, provide an opportunity to investigate such an association. | Adiposity, Adolescent, Adult, Anthropometry, Automobiles, China, Economic Development, Female, Health Surveys, Humans, Longitudinal Studies, Male, Middle Aged, Multivariate Analysis, Nutrition Surveys, Obesity, Ownership, Social Class, Young Adult | null |
22,704,740 | 2012-10-16 | 2022-03-21 | 1873-2607 | American journal of preventive medicine | Walking distance by trip purpose and population subgroups. | Yang Yong, Diez-Roux Ana V | eng | R01-HL071759 (NHLBI NIH HHS, United States); R01 HL071759 (NHLBI NIH HHS, United States); R21-HL106467 (NHLBI NIH HHS, United States); R01 HL071759-08 (NHLBI NIH HHS, United States); R21 HL106467 (NHLBI NIH HHS, United States); R21 HL106467-01A1 (NHLBI NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | null | IM | 22704740, S0749-3797(12)00240-1, 10.1016/j.amepre.2012.03.015, PMC3377942, NIHMS369465, 18567638, 21551387, 19733426, 17481721, 15694518, 12948984, 17958465, 18088416, 21855737, 17590378, 28834523, 17467781, 12350451, 21272299, 18562973, 17489009 | Walking distance is an important concept in the fields of transportation and public health. A distance of 0.25 miles is often used as an acceptable walking distance in U.S. research studies. Overall, research on the distance and duration of walking trips for different purposes and across different population groups remains limited. | Adolescent, Adult, Aged, Child, Child, Preschool, Female, Goals, Health Surveys, Humans, Male, Middle Aged, Motor Activity, Prevalence, Time Factors, United States, Walking, Young Adult | null |
22,704,741 | 2012-10-16 | 2022-04-09 | 1873-2607 | American journal of preventive medicine | Using mHealth technology to enhance self-monitoring for weight loss: a randomized trial. | Burke Lora E, Styn Mindi A, Sereika Susan M, Conroy Molly B, Ye Lei, Glanz Karen, Sevick Mary Ann, Ewing Linda J | eng | K24 NR010742 (NINR NIH HHS, United States); UL1 RR024153 (NCRR NIH HHS, United States); R01-DK071817 (NIDDK NIH HHS, United States); M01 RR000056 (NCRR NIH HHS, United States); P30 NR003924 (NINR NIH HHS, United States); R01 DK071817 (NIDDK NIH HHS, United States); 5M01-RR000056 (NCRR NIH HHS, United States); K24-NR010742 (NINR NIH HHS, United States); R01-DK071817-04S1 (NIDDK NIH HHS, United States); R01-DK071817-05S1 (NIDDK NIH HHS, United States); P30-NR03924 (NINR NIH HHS, United States) | Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural | null | IM | 22704741, S0749-3797(12)00242-5, 10.1016/j.amepre.2012.03.016, PMC3563396, NIHMS378784, 16233990, 14702588, 17823421, 19856202, 18334689, 19246357, 20847736, 20625115, 20679559, 16002825, 18550322, 20935336, 16422134, 17498514, 17904942, 20935337, 7273794, 19141433, 16291981, 21185970, 17035649, 19665588, 18689560, 15687411, 3739819, 19218309, 17216341, 19029500, 16403722 | Self-monitoring for weight loss has traditionally been performed with paper diaries. Technologic advances could reduce the burden of self-monitoring and provide feedback to enhance adherence. | Adult, Computers, Handheld, Diet, Energy Intake, Exercise, Feedback, Psychological, Female, Humans, Male, Middle Aged, Pennsylvania, Self Care, Self Report, Weight Loss | null |
22,704,743 | 2012-10-16 | 2017-11-16 | 1873-2607 | American journal of preventive medicine | Reducing prenatal smoking: the role of state policies. | Adams E Kathleen, Markowitz Sara, Kannan Viji, Dietz Patricia M, Tong Van T, Malarcher Ann M | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704743, S0749-3797(12)00250-4, 10.1016/j.amepre.2012.02.030 | Maternal smoking causes adverse health outcomes for both mothers and infants and leads to excess healthcare costs at delivery and beyond. Even with substantial declines over the past decade, around 23% of women enter pregnancy as a smoker and though almost half quit during pregnancy, half or more quitters resume smoking soon after delivery. | Adult, Female, Health Policy, Humans, Multivariate Analysis, New York City, Population Surveillance, Pregnancy, Prenatal Care, Smoking, Smoking Prevention, State Government, Taxes, United States | null |
22,704,742 | 2012-10-16 | 2022-03-18 | 1873-2607 | American journal of preventive medicine | Prevention of weight gain following a worksite nutrition and exercise program: a randomized controlled trial. | Thorndike Anne N, Sonnenberg Lillian, Healey Erica, Myint-U Khinlei, Kvedar Joseph C, Regan Susan | eng | K23 HL093221 (NHLBI NIH HHS, United States); K23 HL093221-03 (NHLBI NIH HHS, United States); K23 HL93221 (NHLBI NIH HHS, United States) | Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | null | IM | 22704742, S0749-3797(12)00241-3, 10.1016/j.amepre.2012.02.029, PMC3377937, NIHMS369466, 18201641, 11231746, 12684363, 14981225, 21130804, 19765507, 17502536, 21872750, 17888860, 17035649, 11900166, 20075081, 19635784, 15496437, 15917062, 18591433, 7860180, 20879876, 18301173, 18334689, 16908795, 19460655, 16571852, 19343018, 10905529, 21822750, 16966955 | Many employers are now providing wellness programs to help employees make changes in diet and exercise behaviors. Improving health outcomes and reducing costs will depend on whether employees sustain lifestyle changes and maintain a healthy weight over time. | Adult, Cardiovascular Diseases, Female, Hospitals, Teaching, Humans, Male, Massachusetts, Middle Aged, Occupational Health, Overweight, Personnel, Hospital, Program Development, Risk Factors, Weight Gain, Weight Loss, Workplace | null |
22,704,744 | 2012-10-16 | 2022-04-10 | 1873-2607 | American journal of preventive medicine | Graphic warning labels in cigarette advertisements: recall and viewing patterns. | Strasser Andrew A, Tang Kathy Z, Romer Daniel, Jepson Christopher, Cappella Joseph N | eng | R01-120594 (PHS HHS, United States); P20 CA095856 (NCI NIH HHS, United States); P20-CA095856-06 (NCI NIH HHS, United States); P50-CA095856-05 (NCI NIH HHS, United States); P50-CA143187 (NCI NIH HHS, United States); P50 CA143187 (NCI NIH HHS, United States); P50 CA095856 (NCI NIH HHS, United States); R01 CA120594 (NCI NIH HHS, United States) | Journal Article, Randomized Controlled Trial, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | null | IM | 22704744, S0749-3797(12)00207-3, 10.1016/j.amepre.2012.02.026, PMC3377985, NIHMS378783, 17454702, 18768457, 8197891, 2909000, 16754942, 21606180, 14660774, 1932883, 16536669, 19561362, 21401767, 11226354, 9583630, 19726589, 21330273, 19246628, 9849112, 12564550 | The Family Smoking Prevention and Control Act gave the U.S. Food and Drug Administration (FDA) legal authority to mandate graphic warning labels on cigarette advertising and packaging. The FDA requires that these graphic warning labels be embedded into cigarette advertising and packaging by September 2012. | Adult, Advertising, Aged, Attention, Eye Movement Measurements, Female, Humans, Male, Mental Recall, Middle Aged, Photography, Product Labeling, Product Packaging, Smoking, Smoking Prevention, United States, Young Adult | null |
22,704,745 | 2012-10-16 | 2012-06-18 | 1873-2607 | American journal of preventive medicine | Diabetic retinopathy and age-related macular degeneration in the U.S. | Gibson Diane M | eng | null | Journal Article | null | IM | 22704745, S0749-3797(12)00221-8, 10.1016/j.amepre.2012.02.028 | Diabetic retinopathy and age-related macular degeneration (AMD) are two of the most common eye diseases in the U.S. Effective treatments exist for some stages of these conditions. | Adult, Aged, Aged, 80 and over, Awareness, Diabetic Retinopathy, Female, Health Knowledge, Attitudes, Practice, Humans, Macular Degeneration, Male, Middle Aged, Nutrition Surveys, Regression Analysis, United States | null |
22,704,746 | 2012-10-16 | 2022-03-16 | 1873-2607 | American journal of preventive medicine | Unmet eye care needs among U.S. 5th-grade students. | Zhang Xinzhi, Elliott Marc N, Saaddine Jinan B, Berry Jay G, Cuccaro Paula, Tortolero Susan, Franklin Frank, Barker Lawrence E, Schuster Mark A | eng | U19 DP002664 (NCCDPHP CDC HHS, United States); U48 DP000057 (NCCDPHP CDC HHS, United States); U48DP000056 (NCCDPHP CDC HHS, United States); U48 DP000056 (NCCDPHP CDC HHS, United States); U48DP000057 (NCCDPHP CDC HHS, United States); U48DP000046 (NCCDPHP CDC HHS, United States) | Journal Article, Research Support, U.S. Gov't, P.H.S. | null | IM | 22704746, S0749-3797(12)00205-X, 10.1016/j.amepre.2012.01.032 | There is substantial evidence of a disparity in access to eye care services among adults in the U.S.; however, little is known about health disparities for children's eye care. | Adult, Child, Child Health Services, Eyeglasses, Female, Health Services Accessibility, Health Services Needs and Demand, Health Surveys, Healthcare Disparities, Humans, Logistic Models, Male, Medically Uninsured, Middle Aged, Poverty, United States | null |
22,704,747 | 2012-10-16 | 2022-03-30 | 1873-2607 | American journal of preventive medicine | Gender differences in seeking care for falls in the aged Medicare population. | Stevens Judy A, Ballesteros Michael F, Mack Karin A, Rudd Rose A, DeCaro Erin, Adler Gerald | eng | null | Journal Article, Research Support, U.S. Gov't, P.H.S. | null | IM | 22704747, S0749-3797(12)00203-6, 10.1016/j.amepre.2012.03.008 | One third of adults aged ≥65 years fall annually, and women are more likely than men to be treated for fall injuries in hospitals and emergency departments. | Accidental Falls, Aged, Female, Health Care Surveys, Humans, Male, Medicare, Multivariate Analysis, Patient Acceptance of Health Care, Professional-Patient Relations, Sex Distribution, Sex Factors, United States | null |
22,704,748 | 2012-10-16 | 2024-04-13 | 1873-2607 | American journal of preventive medicine | The growth of retail clinics in vaccination delivery in the U.S. | Uscher-Pines Lori, Harris Katherine M, Burns Rachel M, Mehrotra Ateev | eng | KL2 RR024154 (NCRR NIH HHS, United States); KL2 TR000146 (NCATS NIH HHS, United States) | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704748, S0749-3797(12)00202-4, 10.1016/j.amepre.2012.02.024, PMC3710694, NIHMS478585, 11897460, 21293327, 11216113, 19406181, 16602227, 21566026, 28083196, 19721019, 12587814, 19786684, 17516388, 15580726, 21681175, 21216314 | Retail clinics are a promising venue in which to promote and administer vaccinations; however, little is known about who receives vaccinations at a retail clinic. | Adolescent, Adult, Aged, Child, Child, Preschool, Health Services Accessibility, Humans, Immunization Programs, Infant, Influenza A Virus, H1N1 Subtype, Influenza, Human, Measles, Middle Aged, Pneumococcal Infections, Poliomyelitis, Tetanus, United States, Young Adult | null |
22,704,749 | 2012-10-16 | 2022-04-08 | 1873-2607 | American journal of preventive medicine | Smoking cessation and counseling: practices of Canadian physical therapists. | Bodner Michael E, Rhodes Ryan E, Miller William C, Dean Elizabeth | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704749, S0749-3797(12)00206-1, 10.1016/j.amepre.2012.03.009 | Although engaging or supporting smoking cessation with patients is a health priority for health professionals, the degree to which physical therapists do so is unknown. They have a particular responsibility given their professional commitment to patient education, and typical practice pattern (i.e., long, multiple visits). | Adult, Canada, Counseling, Cross-Sectional Studies, Female, Health Care Surveys, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Physical Therapists, Smoking Cessation | null |
22,704,750 | 2012-10-16 | 2012-06-18 | 1873-2607 | American journal of preventive medicine | Physician-patient communication regarding asthma and work. | Mazurek Jacek M, Storey Eileen | eng | null | Journal Article, Research Support, U.S. Gov't, P.H.S. | null | IM | 22704750, S0749-3797(12)00251-6, 10.1016/j.amepre.2012.03.021 | Healthy People 2020-specific respiratory diseases objectives seek to increase the proportion of people with current asthma who receive appropriate asthma care. For adults, this includes a discussion of whether asthma is work-related. | Adolescent, Adult, Asthma, Occupational, Communication, Health Care Surveys, Humans, Logistic Models, Middle Aged, Occupational Exposure, Odds Ratio, Physician-Patient Relations, United States, Young Adult | null |
22,704,751 | 2012-10-16 | 2022-03-30 | 1873-2607 | American journal of preventive medicine | Consumer perceptions of electronic health information exchange. | Ancker Jessica S, Edwards Alison M, Miller Melissa C, Kaushal Rainu | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704751, S0749-3797(12)00216-4, 10.1016/j.amepre.2012.02.027 | Public support will be critical to the success and long-term sustainability of electronic health information exchange (HIE) initiatives currently promoted by federal policy. | Data Collection, Electronic Health Records, Female, Health Knowledge, Attitudes, Practice, Humans, Male, Medical Record Linkage, Middle Aged, New York, Public Opinion | null |
22,704,752 | 2012-10-16 | 2022-04-08 | 1873-2607 | American journal of preventive medicine | Community-engaged interventions on diet, activity, and weight outcomes in U.S. schools: a systematic review. | Krishnaswami Janani, Martinson Marty, Wakimoto Patricia, Anglemeyer Andrew | eng | null | Journal Article, Review, Systematic Review | null | IM | 22704752, S0749-3797(12)00255-3, 10.1016/j.amepre.2012.02.031 | Community engagement literature suggests that capacity-building approaches and community partnership in health intervention design, delivery, and analysis improve outcomes. School communities influence childhood diet and activity patterns affecting lifelong obesity risk. This systematic review's purpose is to assess whether incorporating community engagement principles in school-based interventions influences weight-related outcomes. | Body Weight, Child, Community Networks, Community-Institutional Relations, Diet, Exercise, Female, Health Promotion, Humans, Male, Obesity, Outcome Assessment, Health Care, Schools, United States | null |
22,704,753 | 2012-10-16 | 2022-04-18 | 1873-2607 | American journal of preventive medicine | Updated recommendations for client- and provider-oriented interventions to increase breast, cervical, and colorectal cancer screening. | null | eng | null | Journal Article | null | IM | 22704753, S0749-3797(12)00256-5, 10.1016/j.amepre.2012.04.008 | The Community Preventive Services Task Force (Task Force) recommends increasing screening for breast cancer through use of group education, one-on-one education, client reminders, reducing client out-of-pocket costs, and provider assessment and feedback; increasing screening for cervical cancer through use of one-on-one education, client reminders, and provider assessment and feedback; and increasing screening for colorectal cancer through use of one-on-one education, client reminders, reducing structural barriers to screening, and provider assessment and feedback. The Task Force found insufficient evidence to determine the effectiveness of increasing screening for breast cancer through use of client incentives, mass media, or provider incentives; for cervical cancer screening through use of group education, client incentives, mass media, reducing client out-of-pocket costs, reducing structural barriers, or provider incentives; and for colorectal cancer screening through use of group education, client incentives, mass media, reducing client out-of-pocket costs, or provider incentives. Details of these findings, and some considerations for use, are provided in this article. | Advisory Committees, Breast Neoplasms, Colorectal Neoplasms, Female, Health Planning Guidelines, Health Promotion, Humans, Mass Screening, United States, Uterine Cervical Neoplasms | null |
22,704,757 | 2012-09-17 | 2013-11-21 | 0165-1781 | Psychiatry research | Decreased caudate N-acetyl-l-aspartic acid in pediatric obsessive-compulsive disorder and the effects of behavior therapy. | Whiteside Stephen P H, Abramowitz Jonathan S, Port John D | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Aspartic Acid, N-acetylaspartate | IM | 22704757, S0925-4927(11)00385-4, 10.1016/j.pscychresns.2011.11.010 | The current study used magnetic resonance spectroscopy (MRS) to investigate differences in absolute levels of neurochemicals in the head of the caudate nucleus (HOC) and anterior cingulate cortex (ACC) between 15 children with obsessive-compulsive disorder (OCD) and a matched control group, as well as the effects of behavior therapy on these chemicals. At baseline, absolute levels of N-acetyl-l-aspartate (NAA) in the left HOC were significantly lower in non-medicated patients (N=8) with OCD compared to medicated patients (N=5) and compared to matched controls (N=9). Exploratory analyses provided preliminary data suggesting that behavior therapy is associated with a decrease in Glx (glutamate+glutamine) in the right HOC (N=7). The baseline differences in NAA replicate previous finding from the adult literature and show a relationship between NAA in OCD across the lifespan. The changes in Glx raise the possibility that behavior therapy and medication treat OCD symptoms through similar pathways. | Adolescent, Aspartic Acid, Behavior Therapy, Caudate Nucleus, Child, Female, Gyrus Cinguli, Humans, Magnetic Resonance Spectroscopy, Male, Obsessive-Compulsive Disorder, Treatment Outcome | null |
22,704,755 | 2012-10-16 | 2018-12-01 | 1873-2607 | American journal of preventive medicine | Under-utilization of eye services: a commentary. | Sommer Alfred | eng | null | Journal Article, Comment | null | IM | 22704755, S0749-3797(12)00208-5, 10.1016/j.amepre.2012.03.010 | null | Child Health Services, Eyeglasses, Female, Health Services Accessibility, Health Services Needs and Demand, Humans, Male, Poverty | null |
22,704,754 | 2012-10-16 | 2023-10-28 | 1873-2607 | American journal of preventive medicine | Effectiveness of interventions to increase screening for breast, cervical, and colorectal cancers: nine updated systematic reviews for the guide to community preventive services. | Sabatino Susan A, Lawrence Briana, Elder Randy, Mercer Shawna L, Wilson Katherine M, DeVinney Barbara, Melillo Stephanie, Carvalho Michelle, Taplin Stephen, Bastani Roshan, Rimer Barbara K, Vernon Sally W, Melvin Cathy Lee, Taylor Vicky, Fernandez Maria, Glanz Karen | eng | 3-U48-DP000049 (NCCDPHP CDC HHS, United States); 3-U48-DP000064 (NCCDPHP CDC HHS, United States); 3-U48-DP-000050-1 (NCCDPHP CDC HHS, United States); 3-U48-DP000057 (NCCDPHP CDC HHS, United States); U48 DP000043 (NCCDPHP CDC HHS, United States); 3-U48-DP000059-01 (NCCDPHP CDC HHS, United States); U48 DP000059 (NCCDPHP CDC HHS, United States); 1-U48-DP000043-S1 (NCCDPHP CDC HHS, United States); U48 DP000057 (NCCDPHP CDC HHS, United States) | Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review | null | IM | 22704754, S0749-3797(12)00257-7, 10.1016/j.amepre.2012.04.009 | Screening reduces mortality from breast, cervical, and colorectal cancers. The Guide to Community Preventive Services previously conducted systematic reviews on the effectiveness of 11 interventions to increase screening for these cancers. This article presents results of updated systematic reviews for nine of these interventions. | Adolescent, Adult, Breast Neoplasms, Colorectal Neoplasms, Female, Financing, Personal, Health Promotion, Humans, Mass Screening, Preventive Health Services, Uterine Cervical Neoplasms, Young Adult | null |
22,704,758 | 2013-02-14 | 2022-02-23 | 1750-1172 | Orphanet journal of rare diseases | A generalizable pre-clinical research approach for orphan disease therapy. | Beaulieu Chandree L, Samuels Mark E, Ekins Sean, McMaster Christopher R, Edwards Aled M, Krainer Adrian R, Hicks Geoffrey G, Frey Brendan J, Boycott Kym M, Mackenzie Alex E | eng | R01 GM042699 (NIGMS NIH HHS, United States); R37 GM042699 (NIGMS NIH HHS, United States) | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22704758, 1750-1172-7-39, 10.1186/1750-1172-7-39, PMC3458970, 19578428, 21233271, 18952168, 18417489, 19429507, 20445623, 21871970, 19881490, 18800034, 17287757, 15519609, 14681831, 12068297, 19432426, 17687303, 16250888, 17186018, 10332044, 19663460, 20529924, 21360185, 21784508, 19467855, 21138548, 15625110, 1090826, 19156838, 21612550, 20506564, 20519671, 19850042, 18722008, 20014119, 19648294, 19879948, 16841068, 15608251, 19571805, 18272502, 21976286, 17670938, 21979052, 20622033, 16341065, 21785216, 20609615, 17726481, 21291174, 21071407, 10469842, 16370374, 17450125, 16846798, 20818846, 20679242, 21849665, 18048412, 18095864, 10929718, 21453280, 19823584, 4704890, 18673270, 22004918, 21083385, 16250650, 17921997, 22022947, 15479448, 17008526, 15163592, 21909252 | With the advent of next-generation DNA sequencing, the pace of inherited orphan disease gene identification has increased dramatically, a situation that will continue for at least the next several years. At present, the numbers of such identified disease genes significantly outstrips the number of laboratories available to investigate a given disorder, an asymmetry that will only increase over time. The hope for any genetic disorder is, where possible and in addition to accurate diagnostic test formulation, the development of therapeutic approaches. To this end, we propose here the development of a strategic toolbox and preclinical research pathway for inherited orphan disease. Taking much of what has been learned from rare genetic disease research over the past two decades, we propose generalizable methods utilizing transcriptomic, system-wide chemical biology datasets combined with chemical informatics and, where possible, repurposing of FDA approved drugs for pre-clinical orphan disease therapies. It is hoped that this approach may be of utility for the broader orphan disease research community and provide funding organizations and patient advocacy groups with suggestions for the optimal path forward. In addition to enabling academic pre-clinical research, strategies such as this may also aid in seeding startup companies, as well as further engaging the pharmaceutical industry in the treatment of rare genetic disease. | Computational Biology, Drug Discovery, Genetic Diseases, Inborn, Humans, Rare Diseases, Translational Research, Biomedical | null |
22,704,759 | 2013-01-14 | 2025-01-03 | 1578-1275 | Atencion primaria | [Adherence and knowledge of treatment in hypothyroid patients from a community pharmacy in Seville: a pilot study]. | Mingorance Mingorance M Concepción, García-Jiménez Emilio | spa | null | Letter | Thyroxine | IM | 22704759, S0212-6567(12)00165-5, 10.1016/j.aprim.2012.04.004, PMC7025605, 18358169 | null | Humans, Hypothyroidism, Pharmacies, Pilot Projects, Surveys and Questionnaires, Thyroxine, Assessment of Medication Adherence | null |
22,704,760 | 2012-12-03 | 2024-07-25 | 1578-1275 | Atencion primaria | [Spanish COPD Guidelines (GesEPOC): Pharmacological treatment of stable COPD]. | Miravitlles Marc, Soler-Cataluña Juan José, Calle Myriam, Molina Jesús, Almagro Pere, Quintano José Antonio, Riesco Juan Antonio, Trigueros Juan Antonio, Piñera Pascual, Simón Adolfo, López-Campos José Luis, Soriano Joan B, Ancochea Julio | spa | null | English Abstract, Journal Article, Practice Guideline | Bronchodilator Agents | IM | 22704760, S0212-6567(12)00185-0, 10.1016/j.aprim.2012.04.005, PMC7025253, 20843247, 19144173, 12006425, 21474571, 15130905, 22196477, 21951550, 19523796, 20979471, 19010994, 17178069, 21353517, 21546440, 14522813, 12406823, 16625543, 18836213, 16916334, 22003290, 22282547, 19131231, 10377201, 12728159, 21788524, 19716961, 21802933, 21559550, 16387952, 17053207, 21838890, 11069811, 18555912, 15866309, 17314337, 17158282, 21272339, 21737553, 17196106, 19962815, 19638566, 20522794, 7489800, 12030736, 20109213, 14999112, 19644045, 20075059, 20624667, 21515553, 17975187, 19750192, 21757283, 12535510, 20978028, 17943918, 18723437, 21864166, 21440355, 17301099, 18448019, 15715180, 10743980, 16701637, 22016444, 19007570, 16055868, 19720809, 21428765, 20650988, 17885691, 17463412, 19386683, 16855965, 20116759, 21565915, 21814459, 17310045 | Recognizing the clinical heterogeneity of COPD suggests a specific therapeutic approach directed by the so-called clinical phenotypes of the disease. The Spanish COPD Guidelines (GesEPOC) is an initiative of SEPAR, which, together with the scientific societies involved in COPD patient care, and the Spanish Patient Forum, has developed these new clinical practice guidelines. This present article describes the severity classification and the pharmacological treatment of stable COPD. GesEPOC identifies four clinical phenotypes with differential treatment: non-exacerbator, mixed COPD-asthma, exacerbator with emphysema and exacerbator with chronic bronchitis. Pharmacological treatment of COPD is based on bronchodilation in addition to other drugs depending on the clinical phenotype and severity. Severity is established by the BODE/BODEx multidimensional scales. Severity can also be approximated by assessing airflow obstruction, dyspnea, level of physical activity and history of exacerbations. GesEPOC is a new, more individualized approach to COPD treatment according to the clinical characteristics of the patients. | Algorithms, Bronchodilator Agents, Humans, Phenotype, Pulmonary Disease, Chronic Obstructive, Severity of Illness Index | null |
22,704,761 | 2013-04-30 | 2012-11-12 | 1873-5010 | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society | Towards an individualized protocol for workload increments in cardiopulmonary exercise testing in children and adolescents with cystic fibrosis. | Hulzebos H J, Werkman M S, van Brussel M, Takken T | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704761, S1569-1993(12)00090-2, 10.1016/j.jcf.2012.05.004 | There is no single optimal exercise testing protocol for children and adolescents with cystic fibrosis (CF) that differs widely in age and disease status. The aim of this study was to develop a CF-specific, individualized approach to determine workload increments for a cycle ergometry testing protocol. | Adolescent, Child, Cystic Fibrosis, Databases, Factual, Exercise Test, Exercise Therapy, Exercise Tolerance, Female, Forced Expiratory Volume, Heart Rate, Humans, Linear Models, Male, Models, Biological, Plethysmography, Whole Body, Respiratory Rate, Spirometry | null |
22,704,762 | 2012-11-13 | 2018-12-01 | 1097-6868 | American journal of obstetrics and gynecology | Changes in vaginal breech delivery rates in a single large metropolitan area. | Sheridan Mary, Bick Debra, Bewley Susan | eng | null | Letter, Comment | null | IM | 22704762, S0002-9378(12)00478-4, 10.1016/j.ajog.2012.04.031 | null | Breech Presentation, Delivery, Obstetric, Female, Humans, Pregnancy | null |
22,704,763 | 2012-12-13 | 2012-10-01 | 1097-6868 | American journal of obstetrics and gynecology | A peculiar presentation: for 2 women, a rare infection preceded a more urgent diagnosis. | Grisaru Dan, Raz Yael, Shtabsky Alexander | eng | null | Case Reports, Journal Article | null | IM | 22704763, S0002-9378(12)00587-X, 10.1016/j.ajog.2012.05.024 | null | Actinomyces, Actinomycosis, Aged, 80 and over, Carcinoma, Squamous Cell, Female, Humans, Melanoma, Middle Aged, Uterine Cervical Neoplasms, Vaginal Discharge | null |
22,704,764 | 2012-10-24 | 2021-10-21 | 1097-6868 | American journal of obstetrics and gynecology | Effects of alcohol, lithium, and homocysteine on nonmuscle myosin-II in the mouse placenta and human trophoblasts. | Han Mingda, Neves Ana Luisa, Serrano Maria, Brinez Pilar, Huhta James C, Acharya Ganesh, Linask Kersti K | eng | R01 HL067306 (NHLBI NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't | Central Nervous System Depressants, Lithium Compounds, Homocysteine, Vitamin B Complex, Ethanol, Inositol, Folic Acid, Nonmuscle Myosin Type IIA, Nonmuscle Myosin Type IIB | IM | 22704764, S0002-9378(12)00505-4, 10.1016/j.ajog.2012.05.007, PMC3408570, NIHMS379521, 21947281, 19887570, 20178880, 10791313, 8575637, 16751178, 18697221, 1859444, 6846205, 21420731, 6867945, 20716463, 18418887, 11295572, 9169052, 15886234, 12729566, 8710892, 8994831, 14594953, 15845534, 19638421, 6795717, 20451895, 17200951, 20679233, 18973262, 17320396, 21210153, 8888295, 9356462, 19851336, 18397754, 21239637, 17198728, 17585370, 20840781, 8986742, 17310241, 7684692, 15292239, 16159661, 15654332, 20601875, 19736321, 15854108, 19754460, 10791321, 12243747, 17020881 | Mouse embryonic exposure to alcohol, lithium, and homocysteine results in intrauterine growth restriction (IUGR) and cardiac defects. Our present study focused on the placental effects. We analyzed the hypothesis that expression of nonmuscle myosin (NMM)-II isoforms involved in cell motility, mechanosensing, and extracellular matrix assembly are altered by the 3 factors in human trophoblast (HTR8/SVneo) cells in vitro and in the mouse placenta in vivo. | Animals, Cell Line, Cell Movement, Central Nervous System Depressants, Endothelial Cells, Ethanol, Female, Folic Acid, Homocysteine, Humans, Inositol, Lithium Compounds, Maternal Exposure, Mice, Nonmuscle Myosin Type IIA, Nonmuscle Myosin Type IIB, Placenta, Placental Circulation, Pregnancy, Trophoblasts, Ultrasonography, Doppler, Umbilical Cord, Vitamin B Complex | null |
22,704,765 | 2012-10-24 | 2022-04-08 | 1097-6868 | American journal of obstetrics and gynecology | Transumbilical versus transvaginal retrieval of surgical specimens at laparoscopy: a randomized trial. | Ghezzi Fabio, Cromi Antonella, Uccella Stefano, Bogani Giorgio, Serati Maurizio, Bolis Pierfrancesco | eng | null | Journal Article, Randomized Controlled Trial | null | IM | 22704765, S0002-9378(12)00579-0, 10.1016/j.ajog.2012.05.016 | We sought to compare transumbilical (TU) and transvaginal (TV) route for retrieval of surgical specimens at laparoscopy. | Adult, Dyspareunia, Female, Humans, Laparoscopy, Middle Aged, Ovarian Cysts, Ovariectomy, Pain Measurement, Pain, Postoperative, Patient Satisfaction, Postoperative Complications, Salpingectomy, Umbilicus, Vagina | null |
22,704,766 | 2012-10-24 | 2022-04-09 | 1097-6868 | American journal of obstetrics and gynecology | A randomized trial of preinduction cervical ripening: dinoprostone vaginal insert versus double-balloon catheter. | Cromi Antonella, Ghezzi Fabio, Uccella Stefano, Agosti Massimo, Serati Maurizio, Marchitelli Giulia, Bolis Pierfrancesco | eng | null | Journal Article, Randomized Controlled Trial | Oxytocics, Oxytocin, Dinoprostone | IM | 22704766, S0002-9378(12)00583-2, 10.1016/j.ajog.2012.05.020 | We sought to compare the efficacy of a double-balloon transcervical catheter to that of a prostaglandin (PG) vaginal insert among women undergoing labor induction. | Administration, Intravaginal, Adult, Analgesia, Epidural, Catheterization, Cervical Ripening, Cesarean Section, Delivery, Obstetric, Dinoprostone, Drug Utilization, Female, Humans, Labor, Induced, Length of Stay, Middle Aged, Muscle Hypertonia, Oxytocics, Oxytocin, Postpartum Hemorrhage, Pregnancy, Time Factors, Uterine Contraction, Young Adult | null |
22,704,767 | 2012-10-24 | 2016-11-25 | 1097-6868 | American journal of obstetrics and gynecology | Examining the correlation between placental and serum placenta growth factor in preeclampsia. | Weed Samantha, Bastek Jamie A, Anton Lauren, Elovitz Michal A, Parry Samuel, Srinivas Sindhu K | eng | K12HD001265 (NICHD NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | Biomarkers, PGF protein, human, Pregnancy Proteins, Placenta Growth Factor | IM | 22704767, S0002-9378(12)00486-3, 10.1016/j.ajog.2012.05.003 | Decreased levels of serum placenta growth factor (PlGF) are associated with preeclampsia. We sought to determine whether serum and placental levels of PlGF (sPlGF and pPlGF) are associated with preeclampsia and whether there is a correlation between serum and placental PlGF levels. | Adult, Biomarkers, Case-Control Studies, Enzyme-Linked Immunosorbent Assay, Female, Fetal Growth Retardation, HELLP Syndrome, Humans, Placenta, Placenta Growth Factor, Pre-Eclampsia, Pregnancy, Pregnancy Proteins, Prospective Studies, Young Adult | null |
22,704,768 | 2012-12-04 | 2015-11-19 | 1873-3336 | Journal of hazardous materials | Effect of surface Fe2O3 clusters on the photocatalytic activity of TiO2 for phenol degradation in water. | Sun Qiong, Leng Wenhua, Li Zhen, Xu Yiming | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Ferric Compounds, Water Pollutants, Chemical, titanium dioxide, ferric oxide, Phenol, Hydrogen Peroxide, Titanium | IM | 22704768, S0304-3894(12)00609-7, 10.1016/j.jhazmat.2012.05.098 | Surface modification of TiO(2) with Fe(2)O(3) clusters was made through chemisorption of ferric phthalocyaninetetracarboxylate onto TiO(2), followed by sintering in air to remove organic moiety. Solid characterization with electron paramagnetic resonance spectroscopy and other techniques showed that ferric oxides were highly dispersed on TiO(2) as a noncrystallized cluster, while TiO(2) phases remained unchanged. For phenol degradation in aerated aqueous suspension, only the sample containing less than 0.3 at.% Fe was more active than bare TiO(2) under UV light, whereas no activity was found under visible light. As anatase thermally transferred into rutile, the Fe-containing catalyst became less active than bare TiO(2), mainly ascribed to the increased size of Fe(2)O(3) clusters. In the presence of H(2)O(2), all Fe-containing catalysts were more active than bare TiO(2). Moreover, similar trend in activity among different catalysts was also observed with the formation of hydroxyl radicals, and with the generation of photocurrent measured under N(2) with Fe/TiO(2) electrode. Present work clearly shows that only Fe(2)O(3) clusters in a small size and at low coverage on TiO(2) are beneficial to the photocatalytic reaction, while excess iron oxide is detrimental. Possible mechanism is discussed in the text. | Adsorption, Catalysis, Ferric Compounds, Hydrogen Peroxide, Phenol, Photolysis, Surface Properties, Titanium, Ultraviolet Rays, Water Pollutants, Chemical, Water Purification | null |
22,704,769 | 2014-07-15 | 2017-11-16 | 1873-3336 | Journal of hazardous materials | Anatomy and ultrastructure alterations of Leucaena leucocephala (Lam.) inoculated with mycorrhizal fungi in response to arsenic-contaminated soil. | Schneider Jerusa, Labory Claudia Regina Gontijo, Rangel Wesley Melo, Alves Eduardo, Guilherme Luiz Roberto Guimarães | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Soil, Soil Pollutants, Arsenic | IM | 22704769, S0304-3894(12)00602-4, 10.1016/j.jhazmat.2012.05.091 | Many studies demonstrate the potential application of arbuscular mycorrhizal fungi (AMF) for remediation purposes, but little is known on AMF potential to enhance plant tolerance to arsenic (As) and the mechanisms involved in this process. We carried anatomical and ultrastructural studies to examine this symbiotic association and the characteristics of shoots and roots of Leucaena leucocephala in As-amended soils (35 and 75 mg As dm(-3)). The experiment used 3 AMF isolates from uncontaminated soils: Acaulospora morrowiae, Glomus clarum, and Gigaspora albida; a mixed inoculum derived from combining these 3 isolates (named Mix AMF); and, 3 AMF isolates from As-contaminated areas: A. morrowiae, G. clarum and Paraglomus occultum. Phytotoxicity symptoms due to arsenic contamination appeared during plant growth, especially in treatments without AMF application. Inoculation with G. clarum and the mixture of species (A. morrowiae, G. albida, and G. clarum) resulted in better growth of L. leucocephala in soils with high As concentrations, as well as significant As removal from the soil, showing a potential for using AMF in phytoextraction. Light microscopy (LS), transmission (TEM) and scanning electron microscopies (SEM) studies showed the colonization of the AMF in plant tissues and damage in all treatments, with ultrastructural changes being observed in leaves and roots of L. leucocephala, especially with the addition of 75 mg dm(-3) of As. | Apoptosis, Arsenic, Biodegradation, Environmental, Biomass, Cell Wall, Chloroplasts, Microscopy, Electron, Scanning, Microscopy, Electron, Transmission, Mycorrhizae, Plant Roots, Plant Shoots, Plants, Soil, Soil Microbiology, Soil Pollutants | Electron microscopy, Light microscopy, Mycorrhizae, Phytoprotection |
22,704,770 | 2012-12-04 | 2013-11-21 | 1873-3336 | Journal of hazardous materials | Mesophilic and thermophilic biofiltration of gaseous toluene in a long-term operation: performance evaluation, biomass accumulation, mass balance analysis and isolation identification. | Wang Can, Kong Xin, Zhang Xin-Yue | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Air Pollutants, RNA, Bacterial, RNA, Ribosomal, 16S, Toluene | IM | 22704770, S0304-3894(12)00572-9, 10.1016/j.jhazmat.2012.05.069 | A thermophilic biofilter (TBF) was developed to treat high temperature gaseous toluene (55°C). The performance of TBF was evaluated under various operating conditions, including different inlet concentrations and gas flow rates, and compared with a control mesophilic biofilter (MBF). Furthermore, the leachate, biomass accumulation and pressure drop of filter bed were investigated. The experimental results showed that the TBF achieved high performance removal efficiencies of 90% when the inlet loading was lower than 100 gm(-3)h(-1). Increasing inlet loading resulted in lower performance of TBF compared with MBF. However, the biomass in TBF, in the long-term operation, showed a slow accumulation process than MBF. The specific growth rates of microorganism were 0.0011 day(-1) and 0.0015 day(-1) for TBF and MBF, respectively. The slow growth process in TBF further resulted in a lower pressure drop of filter bed (0.1-0.5 kPa) than that of MBF (7-10 kPa). The leachate from TBF presented a neutral pH and presented a higher TOC contents than those from MBF. The results of three-dimensional fluorescence spectra suggested that the products of toluene biodegradation included some organic acids. A carbon mass balance analysis showed that 47.1% of the removed toluene was converted to biomass in MBF, which was higher than that of MBF with 30.5%. Finally, 16s rRNA gene sequences indicated the dominant microorganisms in the TBF including Brevibacillus sp. and Anoxybacillus sp., while Delftia sp. and Stenotrophomonas sp. in the MBF. | Air Pollutants, Air Pollution, Bacteria, Biodegradation, Environmental, Biomass, Filtration, Hot Temperature, RNA, Bacterial, RNA, Ribosomal, 16S, Toluene | null |
22,704,772 | 2012-12-04 | 2018-12-01 | 1873-3336 | Journal of hazardous materials | Comments on the "A comparative study of chelating and cationic ion exchange resins for the removal of palladium (II) complexes from acidic chloride media". | Alahyari S Ammari, Khanchi A R, Outokesh M, Tayebi A | eng | null | Letter, Comment | Cation Exchange Resins, Chelating Agents, Palladium | IM | 22704772, S0304-3894(12)00598-5, 10.1016/j.jhazmat.2012.05.087 | null | Cation Exchange Resins, Chelating Agents, Palladium | null |
22,704,771 | 2012-12-04 | 2012-07-20 | 1873-3336 | Journal of hazardous materials | Recycling of waste spent catalyst in road construction and masonry blocks. | Taha Ramzi, Al-Kamyani Zahran, Al-Jabri Khalifa, Baawain Mahad, Al-Shamsi Khalid | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Industrial Waste, Metals, Petroleum, Water Pollutants, Chemical | IM | 22704771, S0304-3894(12)00586-9, 10.1016/j.jhazmat.2012.05.083 | Waste spent catalyst is generated in Oman as a result of the cracking process of petroleum oil in the Mina Al-Fahl and Sohar Refineries. The disposal of spent catalyst is of a major concern to oil refineries. Stabilized spent catalyst was evaluated for use in road construction as a whole replacement for crushed aggregates in the sub-base and base layers and as a partial replacement for Portland cement in masonry blocks manufacturing. Stabilization is necessary as the waste spent catalyst exists in a powder form and binders are needed to attain the necessary strength required to qualify its use in road construction. Raw spent catalyst was also blended with other virgin aggregates, as a sand or filler replacement, for use in road construction. Compaction, unconfined compressive strength and leaching tests were performed on the stabilized mixtures. For its use in masonry construction, blocks were tested for unconfined compressive strength at various curing periods. Results indicate that the spent catalyst has a promising potential for use in road construction and masonry blocks without causing any negative environmental impacts. | Catalysis, Compressive Strength, Construction Materials, Extraction and Processing Industry, Industrial Waste, Metals, Petroleum, Recycling, Water Pollutants, Chemical | null |
22,704,773 | 2012-12-04 | 2013-11-21 | 1873-3336 | Journal of hazardous materials | Oxidative stress response in atrazine-degrading bacteria exposed to atrazine. | Zhang Ying, Meng Dongfang, Wang Zhigang, Guo Huosheng, Wang Yang, Wang Xi, Dong Xiaonan | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Herbicides, Soil Pollutants, Catalase, Superoxide Dismutase, Atrazine | IM | 22704773, S0304-3894(12)00548-1, 10.1016/j.jhazmat.2012.05.054 | Rhodobacter sphaeroides W16 and Acinetobacter lwoffii DNS32 which were isolated from soil in cold area subjected to a long-term atrazine application in Heilongjiang Province (China) can degrade atrazine efficiently. The investigation of their antioxidant properties will be useful for bioremediation and engineering applications of atrazine-degrading bacteria. Superoxide dismutase (SOD) and catalase (CAT) from two atrazine-degrading bacteria and one non-atrazine-degrading bacterium were tested for response to the oxidative stress caused by atrazine. Atrazine produced a greater inhibition of growth in Bacillus subtilis B19. The three bacteria apparently produced two activity peaks of SOD and CAT. The results demonstrated all three bacteria possessed a mechanism for atrazine tolerance that may include controlling the cellular redox balance by producing reactive oxygen species (ROS) and the subsequent scavenging of the ROS, but such response was more rapid and at lower levels in the two atrazine-degrading bacteria, suggesting less oxidative damage in these cells upon atrazine exposure. Compared to B. subtilis B19, atrazine-degrading bacteria had relatively high tolerance to atrazine stress, especially R. sphaeroides W16. Therefore, R. sphaeroides W16 and A. lwoffii DNS32 have a good application prospect of bioremediation project for soil contaminated by atrazine in cold area in Heilongjiang Province. | Acinetobacter, Atrazine, Bacillus subtilis, Biodegradation, Environmental, Catalase, Herbicides, Oxidative Stress, Rhodobacter sphaeroides, Soil Pollutants, Superoxide Dismutase | null |
22,704,774 | 2012-12-04 | 2024-01-09 | 1873-3336 | Journal of hazardous materials | Immobilization of Cu(II), Pb(II) and Cd(II) by the addition of rice straw derived biochar to a simulated polluted Ultisol. | Jiang Jun, Xu Ren-kou, Jiang Tian-yu, Li Zhuo | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Metals, Heavy, Soil Pollutants, biochar, Charcoal | IM | 22704774, S0304-3894(12)00597-3, 10.1016/j.jhazmat.2012.05.086 | To develop new remediation methods for acidic soils polluted by heavy metals, the chemical fractions of Cu(II), Pb(II) and Cd(II) in an Ultisol with and without rice straw biochar were compared and the effect of biochar incorporation on the mobility and bioavailability of these metals was investigated. In light of the decreasing zeta potential and increasing CEC, the incorporation of biochar made the negative soil surface charge more negative. Additionally, the soil pH increased markedly after the addition of biochar. These changes in soil properties were advantageous for heavy metal immobilization in the bulk soil. The acid soluble Cu(II) and Pb(II) decreased by 19.7-100.0% and 18.8-77.0%, respectively, as the amount of biochar added increased. The descending range of acid soluble Cd(II) was 5.6-14.1%, which was much lower than that of Cu(II) and Pb(II). When 5.0 mmol/kg of these heavy metals was added, the reducible Pb(II) for treatments containing 3% and 5% biochar was 2.0 and 3.0 times higher than that of samples without biochar, while the reducible Cu(II) increased by 61.6% and 132.6% for the corresponding treatments, respectively. When 3% and 5% biochar was added, the oxidizable portion of Pb(II) increased by 1.18 and 1.94 times, respectively, while the oxidizable portion of Cu(II) increased by 8.13 and 7.16 times, respectively, primarily due to the high adsorption affinity of functional groups of biochar to Cu(II). The residual heavy metal contents were low and changed little with the incorporation of biochar. | Charcoal, Environmental Restoration and Remediation, Metals, Heavy, Oryza, Soil Pollutants | null |
22,704,775 | 2012-12-04 | 2013-11-21 | 1873-3336 | Journal of hazardous materials | Facilitated transport of Pd(II) through a supported liquid membrane (SLM) containing N,N,N',N'-tetra-(2-ethylhexyl) thiodiglycolamide T(2EH)TDGA: a novel carrier. | Ruhela R, Panja S, Sharma J N, Tomar B S, Tripathi S C, Hubli R C, Suri A K | eng | null | Journal Article | Alkanes, Glycolates, Sulfhydryl Compounds, n-dodecane, Nitric Acid, Palladium | IM | 22704775, S0304-3894(12)00567-5, 10.1016/j.jhazmat.2012.05.064 | A novel carrier, N,N,N',N'-tetra-(2-ethylhexyl) thiodiglycolamide, T(2EH)TDGA has been studied for transport of Pd(II) from nitric acid medium across a supported liquid membrane (SLM). Pd(II) was found to be almost quantitatively transported (≈ 99.9%) within 2h from 3.0M HNO(3) medium using 0.05 M T(2EH)TDGA in n-dodecane as carrier and 0.01 M thiourea in 0.2M HNO(3) as strippant. Pd(II) transport was also studied against various parameters like feed acidity, carrier concentration, membrane pore size, etc. Palladium transport was found to be diffusion controlled and the diffusion co-efficient value was found to be 3.56 × 10(-5)cm(2)/s. Selectivity of T(2EH)TDGA for palladium over other fission products was found to be quite high, with the separation factors for Pd, with respect to different fission products being >10(3). With respect to leaching out of carrier from the membrane support, the membrane was found to be stable for six consecutive cycles. Thus, T(2EH)TDGA can be used as an efficient carrier of Pd(II) from nitric acid medium. | Alkanes, Glycolates, Nitric Acid, Palladium, Recycling, Sulfhydryl Compounds | null |
22,704,776 | 2012-12-04 | 2013-11-21 | 1873-3336 | Journal of hazardous materials | Adsorption/desorption of low concentration of carbonyl sulfide by impregnated activated carbon under micro-oxygen conditions. | Wang Xueqian, Qiu Juan, Ning Ping, Ren Xiaoguang, Li Ziyan, Yin Zaifei, Chen Wei, Liu Wei | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Air Pollutants, Hydroxides, Organometallic Compounds, Potassium Compounds, Sulfur Oxides, Cobalt, Carbon, Copper, carbonyl sulfide, Oxygen, potassium hydroxide | IM | 22704776, S0304-3894(12)00595-X, 10.1016/j.jhazmat.2012.05.084 | Activated carbon modified with different impregnants has been studied for COS removal efficiency under micro-oxygen conditions. Activated carbon modified with Cu(NO(3))(2)-CoPcS-KOH (denoted as Cu-Co-KW) is found to have markedly enhanced adsorption purification ability. In the adsorption purification process, the reaction temperature, oxygen concentration, and relative humidity of the gas are determined to be three crucial factors. A breakthrough of 43.34 mg COS/g adsorbent at 60°С and 30% relative humidity with 1.0% oxygen is shown in Cu-Co-KW for removing COS. The structures of the activated carbon samples are characterized using nitrogen adsorption, and their surface chemical structures are analyzed with X-ray photoelectron spectroscopy (XPS). Modification of Cu(NO(3))(2)-CoPcS-KOH appears to improve the COS removal capacity significantly, during which, SO(4)(2-) is presumably formed, strongly adsorbed, and present in the micropores ranging from 0.7 to 1.5 nm. TPD is used to identify the products containing sulfur species on the carbon surface, where SO(2) and COS are detected in the effluent gas generated from exhausted Cu-Co-KW (denoted Cu-Co-KWE). According to the current study results, the activated carbon impregnated with Cu(NO(3))(2)-CoPcS-KOH promises a good candidate for COS adsorbent, with the purified gas meeting requirements for desirable chemical feed stocks. | Adsorption, Air Pollutants, Air Pollution, Carbon, Cobalt, Copper, Humidity, Hydroxides, Organometallic Compounds, Oxygen, Photoelectron Spectroscopy, Porosity, Potassium Compounds, Sulfur Oxides, Temperature | null |
22,704,777 | 2012-10-16 | 2022-03-30 | 1474-4457 | The Lancet. Infectious diseases | Tuberculosis control: business models for the private sector. | Baloch Noor Ahmad, Pai Madhukar | eng | null | Journal Article, Comment | null | IM | 22704777, S1473-3099(12)70122-6, 10.1016/S1473-3099(12)70122-6 | null | Disease Notification, Female, Health Education, Humans, Male, Mass Screening, Public-Private Sector Partnerships, Tuberculosis, Pulmonary, Urban Health Services | null |
22,704,778 | 2012-10-16 | 2022-04-09 | 1474-4457 | The Lancet. Infectious diseases | Engaging the private sector to increase tuberculosis case detection: an impact evaluation study. | Khan Aamir J, Khowaja Saira, Khan Faisal S, Qazi Fahad, Lotia Ismat, Habib Ali, Mohammed Shama, Khan Uzma, Amanullah Farhana, Hussain Hamidah, Becerra Mercedes C, Creswell Jacob, Keshavjee Salmaan | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704778, S1473-3099(12)70116-0, 10.1016/S1473-3099(12)70116-0 | In many countries with a high burden of tuberculosis, most patients receive treatment in the private sector. We evaluated a multifaceted case-detection strategy in Karachi, Pakistan, targeting the private sector. | Adolescent, Adult, Aged, Aged, 80 and over, Algorithms, Ambulatory Care Facilities, Analysis of Variance, Cell Phone, Chi-Square Distribution, Child, Child, Preschool, Disease Notification, Female, Health Education, Humans, Infant, Male, Mass Screening, Middle Aged, Motivation, Pakistan, Patient Acceptance of Health Care, Public-Private Sector Partnerships, Referral and Consultation, Retrospective Studies, Tuberculosis, Pulmonary, Urban Health Services, Young Adult | null |
22,704,779 | 2013-07-22 | 2014-11-20 | 1873-4847 | The Journal of nutritional biochemistry | Different effects of catechin on angiogenesis and inflammation depending on VEGF levels. | Negrão Rita, Costa Raquel, Duarte Delfim, Gomes Tiago Taveira, Azevedo Isabel, Soares Raquel | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Vascular Endothelial Growth Factor A, Catechin | IM | 22704779, S0955-2863(12)00037-X, 10.1016/j.jnutbio.2011.12.011 | Although physiological and pathological angiogenesis develop through similar processes, during pathological angiogenesis, proangiogenic factors are exacerbated. Polyphenols have been considered therapeutic tools for conditions exhibiting enhanced angiogenesis. However, the possibility that these compounds may also prevent vascularization in physiological situations is a major drawback for their use. The purpose of the current study was to investigate the effects of 0.1-100 μM catechin on endothelial cells (EC) and vascular smooth muscle cells (VSMC) regarding angiogenic and inflammatory processes. Catechin modulation of angiogenesis and inflammation was also evaluated in vivo using different models of angiogenesis: one physiological (skin wound-healing assay) and another one resembling pathological angiogenesis, exhibiting higher vascular endothelial growth factor (VEGF)-A stimulation (Matrigel plug assay). The in vitro results showed that 100 μM catechin increased viability (to 165.58% and to 165.34%) and decreased apoptosis (53.45% and 92.65%) and proliferation (33.19% and 23.36%) of EC and VSMC, respectively. Catechin affected migration and invasion, tending to increase both in EC and decreasing them in VSMC; however, it did not change sprouting angiogenesis. Nevertheless, catechin diminished in vitro inflammatory modulators such as tumor necrosis factor α (58.66% for human umbilical vein endothelial cells and 85.46% for human aortic smooth muscle cells) and nuclear factor kappa-B (38.43% for VSMC). The in vivo results demonstrated that catechin did not change angiogenesis and inflammation in skin wound-healing model and substantially decreased these processes in Matrigel plug assay. Altogether, the current study showed that catechin has different effects in angiogenesis and inflammation depending on VEGF-A levels. The absence of adverse effects in mature vasculature favors catechin potential use against pathological situations where angiogenesis is stimulated. | Animals, Aorta, Apoptosis, Catechin, Cell Movement, Dose-Response Relationship, Drug, Endothelial Cells, Human Umbilical Vein Endothelial Cells, Humans, In Vitro Techniques, Inflammation, Muscle, Smooth, Vascular, Neovascularization, Physiologic, Rats, Rats, Wistar, Vascular Endothelial Growth Factor A, Wound Healing | null |
22,704,780 | 2013-07-22 | 2016-11-25 | 1873-4847 | The Journal of nutritional biochemistry | Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo. | Cheng Yu-Ting, Wu Chi-Hao, Ho Cheng-Ying, Yen Gow-Chin | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Membrane Proteins, NF-E2-Related Factor 2, NFE2L2 protein, human, Protective Agents, Reactive Oxygen Species, Catechin, Ketoprofen, L-Lactate Dehydrogenase, Glutathione Peroxidase, Heme Oxygenase-1, Cyclooxygenase 1, Ptgs1 protein, rat, Glutathione | IM | 22704780, S0955-2863(12)00042-3, 10.1016/j.jnutbio.2012.01.010 | Nonsteroidal anti-inflammatory drugs (NSAIDs), including ketoprofen, are widely used in clinical medicine. However, these drugs may damage the gastrointestinal mucosa. Some reports have suggested that intestinal diseases, such as ulcers, are associated with lipid peroxidation and oxidative damage in the mucosa. Phytochemicals, such as polyphenols, are common dietary antioxidants that possess many beneficial characteristics, such as antioxidant and anti-inflammatory capabilities. The objective of this study was to investigate the protective effects of polyphenols on ketoprofen-induced oxidative damage in the gastrointestinal mucosa. We evaluated the effects of catechin, theaflavin, malvidin, cyanidin and apigenin on the activity of antioxidant enzymes in human intestinal-407 (Int-407) cells and rat primary gastric cells treated with ketoprofen. The results indicated that catechin significantly (P<.05) decreased the levels of lipid peroxidation (40.5%) and reactive oxygen species (30.0%), and increased the activity of intracellular antioxidant enzymes glutathione peroxidase, glutathione reductase and total sulfhydryl groups. More importantly, the treatment of Sprague-Dawley rats with catechin (35 mg/kg/day) prior to the administration of ketoprofen (50 mg/kg/day) successfully inhibited oxidative damage and reversed the impairment of the antioxidant system in the intestinal mucosa. Western blot analysis revealed that catechin stimulated a time-dependent increase in both the nuclear factor erythroid 2-related factor 2 and total heme oxygenase-1 protein expression in Int-407 cells. These results suggest that catechin may have a protective effect on gastrointestinal ulcers. | Animals, Catechin, Cell Line, Cyclooxygenase 1, DNA Damage, Gastric Mucosa, Glutathione, Glutathione Peroxidase, Heme Oxygenase-1, Humans, Intestinal Mucosa, Ketoprofen, L-Lactate Dehydrogenase, Lipid Peroxidation, Male, Membrane Proteins, NF-E2-Related Factor 2, Oxidative Stress, Protective Agents, Rats, Rats, Sprague-Dawley, Reactive Oxygen Species, Up-Regulation | null |
22,704,781 | 2013-05-24 | 2022-02-23 | 1873-4847 | The Journal of nutritional biochemistry | RETRACTED: Curcumin restores Nrf2 levels and prevents quinolinic acid-induced neurotoxicity. | Carmona-Ramírez Iván, Santamaría Abel, Tobón-Velasco Julio C, Orozco-Ibarra Marisol, González-Herrera Irma G, Pedraza-Chaverrí José, Maldonado Perla D | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Retracted Publication | NF-E2-Related Factor 2, Nfe2l2 protein, rat, Protective Agents, Glutathione Peroxidase, Superoxide Dismutase, Quinolinic Acid, Curcumin | IM | 22704781, S0955-2863(12)00033-2, 10.1016/j.jnutbio.2011.12.010 | Neurological diseases comprise a group of heterogeneous disorders characterized by progressive brain dysfunction and cell death. In the next years, these diseases are expected to constitute a world-wide health problem. Because excitotoxicity and oxidative stress are involved in neurodegenerative diseases, it becomes relevant to describe pharmacological therapies designed to activate endogenous cytoprotective systems. Activation of transcription factor Nrf2 stimulates cytoprotective vitagenes involved in antioxidant defense. In this work, we investigated the ability of the antioxidant curcumin to induce transcription factor Nrf2 in a neurodegenerative model induced by quinolinic acid in rats. Animals were administered with curcumin (400 mg/kg, p.o.) for 10 days, and then intrastriatally infused with quinolinic acid (240 nmol) on day 10 of treatment. Curcumin prevented rotation behavior (6 days post-lesion), striatal morphological alterations (7 days post-lesion) and neurodegeneration (1 and 3 days post-lesion) induced by quinolinic acid. Curcumin also reduced quinolinic acid-induced oxidative stress (measured as protein carbonyl content) at 6 h post-lesion. The protective effects of curcumin were associated to its ability to prevent the quinolinic acid-induced decrease of striatal intra-nuclear Nrf2 levels (30 and 120 min post-lesion), and total superoxide dismutase and glutathione peroxidase activities (1 day post-lesion). Therefore, results of this study support the concept that neuroprotection induced by curcumin is associated with its ability to activate the Nrf2 cytoprotective pathway and to increase the total superoxide dismutase and glutathione peroxidase activities. | Animals, Corpus Striatum, Curcumin, Glutathione Peroxidase, Male, NF-E2-Related Factor 2, Neurodegenerative Diseases, Neurotoxicity Syndromes, Oxidative Stress, Protective Agents, Quinolinic Acid, Rats, Rats, Wistar, Superoxide Dismutase | null |
22,704,782 | 2013-07-22 | 2020-12-09 | 1873-4847 | The Journal of nutritional biochemistry | Activation of phosphatidylinositol-3 kinase, AMP-activated kinase and Akt substrate-160 kDa by trans-10, cis-12 conjugated linoleic acid mediates skeletal muscle glucose uptake. | Mohankumar Suresh K, Taylor Carla G, Siemens Linda, Zahradka Peter | eng | null | Journal Article, Research Support, Non-U.S. Gov't | GTPase-Activating Proteins, Glucose Transporter Type 4, Insulin, Linoleic Acids, Conjugated, Ribonucleotides, Slc2a4 protein, rat, TBC1D4 protein, rat, cis-9, trans-11-conjugated linoleic acid, trans-10,cis-12-conjugated linoleic acid, Aminoimidazole Carboxamide, Phosphatidylinositol 3-Kinase, AMP-Activated Protein Kinases, AICA ribonucleotide, Glucose | IM | 22704782, S0955-2863(12)00038-1, 10.1016/j.jnutbio.2012.01.006 | Conjugated linoleic acid (CLA), a dietary lipid, has been proposed as an antidiabetic agent. However, studies specifically addressing the molecular dynamics of CLA on skeletal muscle glucose transport and differences between the key isomers are limited. We demonstrate that acute exposure of L6 myotubes to cis-9, trans-11 (c9,t11) and trans-10, cis-12 (t10,c12) CLA isomers mimics insulin action by stimulating glucose uptake and glucose transporter-4 (GLUT4) trafficking. Both c9,t10-CLA and t10,c12-CLA stimulate the phosphorylation of phosphatidylinositol 3-kinase (PI3-kinase) p85 subunit and Akt substrate-160 kDa (AS160), while showing isomer-specific effects on AMP-activated protein kinase (AMPK). CLA isomers showed synergistic effects with the AMPK activator, 5-aminoimidazole-4-carboxamide-1-β-d-ribonucleoside (AICAR). Blocking PI3-kinase and AMPK prevented the stimulatory effects of t10,c12-CLA on AS160 phosphorylation and glucose uptake, indicating that this isomer acts via a PI3-kinase and AMPK-dependent mechanism, whereas the mechanism of c9,t11-CLA remains unclear. Intriguingly, CLA isomers sensitized insulin-Akt-responsive glucose uptake and prevented high insulin-induced Akt desensitisation. Together, these results establish that CLA exhibits isomer-specific effects on GLUT4 trafficking and the increase in glucose uptake induced by CLA treatment of L6 myotubes occurs via pathways that are distinctive from those utilised by insulin. | AMP-Activated Protein Kinases, Aminoimidazole Carboxamide, Animals, Cell Membrane, Drug Synergism, GTPase-Activating Proteins, Glucose, Glucose Transporter Type 4, Insulin, Linoleic Acids, Conjugated, Muscle Fibers, Skeletal, Muscle, Skeletal, Phosphatidylinositol 3-Kinase, Phosphorylation, Protein Transport, Rats, Ribonucleotides | null |
22,704,783 | 2013-07-22 | 2018-12-02 | 1873-4847 | The Journal of nutritional biochemistry | Anti-angiogenic effects of lycopene through immunomodualtion of cytokine secretion in human peripheral blood mononuclear cells. | Huang Chin-Shiu, Chuang Cheng-Hung, Lo Tsue-Feng, Hu Miao-Lin | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Angiogenesis Inhibitors, Culture Media, Conditioned, Cytokines, Immunologic Factors, Vascular Endothelial Growth Factor A, Interleukin-12, Carotenoids, Dexamethasone, Interferon-gamma, Matrix Metalloproteinase 2, Lycopene | IM | 22704783, S0955-2863(12)00034-4, 10.1016/j.jnutbio.2012.01.003 | The carotenoid lycopene has been reported to possess anti-metastatic activity which may be associated with immunomodulation. However, the anti-angiogenic effects and mechanisms of action of lycopene have not been reported. In this study, we investigated the immunomodulatory effect on in vitro and ex vivo angiogenesis of lycopene. We found that the proliferation, migration and the matrigel tube formation of human umbilical vein endothelial cells (HUVECs) was remarkably inhibited by conditioned medium (CM) of human peripheral blood mononuclear cells (MNC-CM) stimulated with various dose (1-10 μmol/L) of lycopene (LP-MNC-CM). LP-MNC-CM treatment inhibited ex vivo angiogenesis, as revealed by chicken egg chorioallantoic membrane assay. We further examined the effects of lycopene stimulation on cytokine levels in MNC and showed that, as compared to the control, lycopene (10 μmol/L) significantly (P<.001) up-regulated interleukin (IL)-12 by 163% and interferon (IFN)-γ by 531%. Furthermore, pre-treatment of HUVECs with dexamethasone, an IL-12 inhibitor, blocked the anti-angiogenic effects of LP-MNC-CM in parallel with inhibition of IL-12 and IFN-γ induction in MNC. These results demonstrate that lycopene has a potent anti-angiogenic effect and that these effect may be associated with its up-regulation of IL-12 and IFN-γ. | Adult, Angiogenesis Inhibitors, Animals, Carotenoids, Cell Movement, Cell Proliferation, Chick Embryo, Chorioallantoic Membrane, Culture Media, Conditioned, Cytokines, Dexamethasone, Human Umbilical Vein Endothelial Cells, Humans, Immunologic Factors, Interferon-gamma, Interleukin-12, Leukocytes, Mononuclear, Lycopene, Matrix Metalloproteinase 2, Vascular Endothelial Growth Factor A, Young Adult | null |
22,704,784 | 2012-12-31 | 2022-04-09 | 1879-0267 | Injury | Epidural analgesia for blunt thoracic injury--which patients benefit most? | Yeh Daniel Dante, Kutcher Matthew E, Knudson M Margaret, Tang Julin F | eng | null | Journal Article | null | IM | 22704784, S0020-1383(12)00208-2, 10.1016/j.injury.2012.05.022 | Epidural analgesia for blunt thoracic injury has been demonstrated to be beneficial for pulmonary function, analgesia, and subjective pain; however the optimal patient selection and timing of thoracic epidural placement have not been well studied. We hypothesised that early (<48h) epidural analgesia (EA) as compared with usual care involving oral and intravenous narcotics delivered by patient-controlled analgesia (PCA) in patients with blunt thoracic trauma (>3 ribs fractured) is associated with fewer pulmonary complications and lower resource utilisation as measured by ICU and hospital length of stay. | Adult, Aged, Analgesia, Epidural, Analgesia, Patient-Controlled, Chest Tubes, Cost-Benefit Analysis, Female, Humans, Intensive Care Units, Length of Stay, Male, Middle Aged, Pain, Patient Selection, Retrospective Studies, Rib Fractures, Treatment Outcome, United States, Wounds, Nonpenetrating | null |
22,704,785 | 2013-01-24 | 2012-09-03 | 1095-9254 | Journal of adolescence | Factors associated with substance use among orphaned and non-orphaned youth in South Africa. | Meghdadpour Susanne, Curtis Sian, Pettifor Audrey, MacPhail Catherine | eng | null | Journal Article | null | IM | 22704785, S0140-1971(12)00082-6, 10.1016/j.adolescence.2012.05.005 | Substance use is increasing among youth in South Africa, and may be contributing to transmission of HIV. As parental death often leaves youth with altered emotional and physical resources, substance use may be greater among orphaned adolescents. Utilizing data from a household survey of 15-24 year old South Africans (n = 11,904), multivariable models were fitted to examine the association of factors from five domains with alcohol and drug use, and to compare substance use among orphaned versus non-orphaned youth. Results showed that factors from individual, family, and community domains were most associated with substance use. Compared with non-orphans, paternal and double orphaned males were more likely to have consumed alcohol, and paternally orphaned females had significantly greater odds of having used drugs. Findings confirm that some sub-groups of orphaned youth are at increased risk of substance use and families and communities may be influential in moderating this risky behavior. | Adolescent, Adolescent Behavior, Child, Orphaned, Cross-Sectional Studies, Female, Humans, Male, Multivariate Analysis, Odds Ratio, Risk Factors, Risk-Taking, Self Report, Socialization, South Africa, Substance-Related Disorders, Young Adult | null |
22,704,786 | 2013-09-30 | 2019-12-10 | 1488-2361 | Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes | Acute- or subacute-onset lung complications in treating patients with rheumatoid arthritis. | Nakajima Reiko, Sakai Fumikazu, Mimura Toshihide, Tokuda Hitoshi, Takahashi Masahiro, Kimura Fumiko | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | Antirheumatic Agents | IM | 22704786, S0846-5371(11)00209-9, 10.1016/j.carj.2011.12.017 | Rheumatoid arthritis (RA) is a common systemic disease that manifests as inflammatory arthritis of multiple joints and produces a wide variety of intrathoracic lesions, including pleural diseases, diffuse interstitial pneumonia, rheumatoid nodules, and airway disease. Patients treated for RA can have associated lung disease that commonly manifests as diffuse interstitial pneumonia, drug-induced lung injury, and infection. The purpose of this pictorial review is to illustrate the radiographic and clinical features of lung complications of acute or subacute onset in patients treated for RA and to show the computed tomography features of these complications. | Acute Disease, Antirheumatic Agents, Arthritis, Rheumatoid, Cryptogenic Organizing Pneumonia, Humans, Infections, Lung, Lung Diseases, Lung Diseases, Interstitial, Lung Injury, Tomography, X-Ray Computed | Acute or subacute onset, Lung complications, Rheumatoid arthritis |
22,704,787 | 2013-03-04 | 2018-12-01 | 1699-7980 | Actas urologicas espanolas | [Laparoendoscopic radical cystectomy with orthotopic ileal neobladder through umbilical single port]. | Angulo J C, Cáceres F, Arance I, Romero I, Ramón De Fata F, Cabrera P M | spa | null | Journal Article, Review | null | IM | 22704787, S0210-4806(12)00109-X, 10.1016/j.acuro.2012.03.005 | Radical cystectomy with orthotopic derivation is one of the most complex urological techniques, although laparoscopic surgery has made this procedure increasingly less invasive. | Cicatrix, Cystectomy, Evidence-Based Medicine, Female, Humans, Ileum, Laparoscopy, Lymph Node Excision, Male, Minimally Invasive Surgical Procedures, Natural Orifice Endoscopic Surgery, Pain, Postoperative, Postoperative Complications, Treatment Outcome, Umbilicus, Urinary Diversion | null |
22,704,788 | 2012-12-03 | 2012-07-09 | 1699-7980 | Actas urologicas espanolas | [Onset of a training program for single-port laparoscopic urology]. | Cáceres F, Cabrera P M, Mateo E, Andrés G, Lista F, García-Tello A, Angulo J C | spa | null | English Abstract, Journal Article | null | IM | 22704788, S0210-4806(12)00116-7, 10.1016/j.acuro.2012.03.012 | To describe the onset of a single port laparoendoscopic program to carry out oncology surgery in a Urology Service. We present the initial experience in the laboratory and in the Animal Facility with rigid precurved instruments and KeyPort reusable access element (Richard Wolf). | Animals, Equipment Design, Laparoscopy, Models, Animal, Swine, Urologic Surgical Procedures | null |
22,704,790 | 2012-12-17 | 2016-11-25 | 1769-6666 | Chirurgie de la main | [Relationship between midcarpal inclination angle and scaphoid kinematic]. | Ardouin L, Racca M G, Garcia-Elias M | fre | null | Journal Article | null | IM | 22704790, S1297-3203(12)00053-4, 10.1016/j.main.2012.04.005 | To investigate if there is a correlation between the so-called midcarpal inclination angle and the kinematic behavior of the scaphoid. | Adult, Biomechanical Phenomena, Carpal Bones, Female, Humans, Male, Radiography, Scaphoid Bone | null |
22,704,791 | 2013-01-08 | 2015-11-19 | 1879-0070 | Diagnostic microbiology and infectious disease | LEADER surveillance program results for 2010: an activity and spectrum analysis of linezolid using 6801 clinical isolates from the United States (61 medical centers). | Flamm Robert K, Farrell David J, Mendes Rodrigo E, Ross James E, Sader Helio S, Jones Ronald N | eng | null | Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't | Acetamides, Anti-Bacterial Agents, Oxazolidinones, Linezolid | IM | 22704791, S0732-8893(12)00194-0, 10.1016/j.diagmicrobio.2012.05.012 | The LEADER program monitors the in vitro activity of linezolid and comparator agents across the United States using reference broth microdilution and supportive molecular susceptibility-based investigations. This report summarizes the data from the 2010 program, the seventh consecutive year. A total of 61 medical centers from the USA including 7 medical centers specializing in children's healthcare provided a total of 6801 Gram-positive pathogens. The medical centers represented all 9 US Bureau of Census geographic regions. The organisms tested by reference broth microdilution were 3105 Staphylococcus aureus, 944 coagulase-negative staphylococci (CoNS), 934 Enterococci, 803 Streptococcus pneumoniae, 604 β-haemolytic streptococci, and 411 viridans group and other streptococci. The MIC(90) value for each of the above 6 targeted groups of organisms was 1 μg/mL. The "all organism" linezolid-resistant and nonsusceptible rate was 0.38%, which has been constant at 0.34% (2009) to 0.45% (2006) for the last 4 years. For Staphylococcus aureus, only 0.06% of the isolates were linezolid-resistant (MIC, ≥8 μg/mL); however, 2 additional methicillin-resistant Staphylococcus aureus had a cfr and a MIC of only 4 μg/mL. Resistance to linezolid was detected in 7 enterococci (0.75%) and 14 CoNS isolates (1.48%). This also represents a stable rate of resistance noted since the 2006 LEADER program report. Of note, for the first time in the 7 years of the Leader Program a linezolid-resistant Streptococcus pneumoniae was encountered. Overall, the results of the LEADER program demonstrate that linezolid maintains excellent in vitro activity against target Gram-positive pathogens across the USA. The LEADER program continues to provide valuable reference and molecular-level monitoring of linezolid activity. | Acetamides, Anti-Bacterial Agents, Drug Resistance, Bacterial, Humans, Linezolid, Microbial Sensitivity Tests, Oxazolidinones, Staphylococcal Infections, Staphylococcus, Streptococcal Infections, Streptococcus, United States | null |
22,704,789 | 2013-01-08 | 2012-08-24 | 1542-2224 | The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons | Management of failed and infected first metatarsophalangeal joint implant arthroplasty by reconstruction with an acellular dermal matrix: a case report. | Khoury Wissam E, Fahim Ramy, Sciulli Jessica M, Ehredt Duane J | eng | null | Journal Article | null | IM | 22704789, S1067-2516(12)00183-4, 10.1053/j.jfas.2012.04.014 | Management of failed first metatarsophalangeal joint implant arthroplasty, especially in the face of infection, is an area of debate without a clear consensus. The purpose of the present report was to explore a new option of reconstructing the joint with an acellular dermal matrix substance in a single case study during a 12-month follow-up period. A staged approach that began with removal of the failed 2-component great toe implant, Koenig(®), excisional debridement of the wound with resection of the necrotic bone (proximal phalanx and distal portion of the first metatarsal bones), and culture-specific antibiosis therapy. The final stage included incorporating the acellular dermal matrix, Graftjacket(®) into the joint in an accordion-type fashion, and reconstruction of the joint capsule. Postoperative radiographs revealed a more rectus joint with some improvement in length. At 6 months postoperatively, magnetic resonance imaging revealed incorporation of the graft material into the joint. Finally, at the 1-year mark, the patient was pain free with satisfactory function at the first metatarsophalangeal joint during gait. This is the first reported case of salvaging failed and infected first metatarsophalangeal joint implant arthroplasty with incorporation of the acellular dermal matrix and provides a new option to consider in the future. | Acellular Dermis, Aged, Arthroplasty, Debridement, Device Removal, Female, Hallux Rigidus, Humans, Joint Prosthesis, Metatarsophalangeal Joint, Prosthesis Failure, Prosthesis-Related Infections, Reoperation, Staphylococcal Infections, Staphylococcus aureus | null |
22,704,792 | 2014-02-18 | 2022-04-08 | 1520-4898 | Accounts of chemical research | Carbohydrate-aromatic interactions. | Asensio Juan Luis, Ardá Ana, Cañada Francisco Javier, Jiménez-Barbero Jesús | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Carbohydrates, Hydrocarbons, Aromatic, Monosaccharides, Proteins, Water | IM | 22704792, 10.1021/ar300024d | The recognition of saccharides by proteins has far reaching implications in biology, technology, and drug design. Within the past two decades, researchers have directed considerable effort toward a detailed understanding of these processes. Early crystallographic studies revealed, not surprisingly, that hydrogen-bonding interactions are usually involved in carbohydrate recognition. But less expectedly, researchers observed that despite the highly hydrophilic character of most sugars, aromatic rings of the receptor often play an important role in carbohydrate recognition. With further research, scientists now accept that noncovalent interactions mediated by aromatic rings are pivotal to sugar binding. For example, aromatic residues often stack against the faces of sugar pyranose rings in complexes between proteins and carbohydrates. Such contacts typically involve two or three CH groups of the pyranoses and the π electron density of the aromatic ring (called CH/π bonds), and these interactions can exhibit a variety of geometries, with either parallel or nonparallel arrangements of the aromatic and sugar units. In this Account, we provide an overview of the structural and thermodynamic features of protein-carbohydrate interactions, theoretical and experimental efforts to understand stacking in these complexes, and the implications of this understanding for chemical biology. The interaction energy between different aromatic rings and simple monosaccharides based on quantum mechanical calculations in the gas phase ranges from 3 to 6 kcal/mol range. Experimental values measured in water are somewhat smaller, approximately 1.5 kcal/mol for each interaction between a monosaccharide and an aromatic ring. This difference illustrates the dependence of these intermolecular interactions on their context and shows that this stacking can be modulated by entropic and solvent effects. Despite their relatively modest influence on the stability of carbohydrate/protein complexes, the aromatic platforms play a major role in determining the specificity of the molecular recognition process. The recognition of carbohydrate/aromatic interactions has prompted further analysis of the properties that influence them. Using a variety of experimental and theoretical methods, researchers have worked to quantify carbohydrate/aromatic stacking and identify the features that stabilize these complexes. Researchers have used site-directed mutagenesis, organic synthesis, or both to incorporate modifications in the receptor or ligand and then quantitatively analyzed the structural and thermodynamic features of these interactions. Researchers have also synthesized and characterized artificial receptors and simple model systems, employing a reductionistic chemistry-based strategy. Finally, using quantum mechanics calculations, researchers have examined the magnitude of each property's contribution to the interaction energy. | Carbohydrates, Drug Design, Hydrocarbons, Aromatic, Hydrogen Bonding, Models, Molecular, Monosaccharides, Proteins, Thermodynamics, Water | null |
22,704,793 | 2013-12-11 | 2016-05-18 | 1876-4754 | Brain stimulation | Numerical estimation of the current density in the heart during transcranial direct current stimulation. | Parazzini Marta, Rossi Elena, Rossi Lorenzo, Priori Alberto, Ravazzani Paolo | eng | null | Letter | null | IM | 22704793, S1935-861X(12)00089-7, 10.1016/j.brs.2012.05.007 | null | Adult, Biophysics, Child, Electric Stimulation, Electromyography, Family, Female, Humans, Magnetic Resonance Imaging, Male, Models, Biological, Muscle, Skeletal, Myocardium, User-Computer Interface | null |
22,704,794 | 2013-03-14 | 2018-12-01 | 1873-5967 | Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology | Re: "Performance of an alternative laboratory based algorithm for HIV diagnosis in a high risk population". | Apfelroth Stephen | eng | null | Letter, Comment | RNA, Viral | IM | 22704794, S1386-6532(12)00207-7, 10.1016/j.jcv.2012.04.025 | null | Algorithms, Diagnostic Techniques and Procedures, HIV Infections, Humans, Mass Screening, RNA, Viral | null |
22,704,796 | 2013-05-22 | 2021-10-21 | 1873-6882 | Current opinion in neurobiology | Neural basis of learning and preference during social decision-making. | Seo Hyojung, Lee Daeyeol | eng | R01 DA029330 (NIDA NIH HHS, United States); DA024855 (NIDA NIH HHS, United States); DA029330 (NIDA NIH HHS, United States); RL1 DA024855 (NIDA NIH HHS, United States); P20 DA027844 (NIDA NIH HHS, United States); DA027844 (NIDA NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Review | null | IM | 22704796, S0959-4388(12)00098-0, 10.1016/j.conb.2012.05.010, PMC3449007, NIHMS382446, 18509023, 22053054, 21982377, 20538951, 21964488, 19443777, 20381353, 17030808, 20071521, 18427116, 21256015, 19805082, 22307594, 22308343, 9658025, 18466754, 17023614, 20182511, 21220339, 18323447, 21041646, 19005555, 16095886, 20739566, 19443783, 15004564, 12948738, 16311337, 21616156, 19940165, 12805551, 17670983, 21559322, 20702705, 19470476, 20023652, 21609828, 21942764, 21435563, 22106300, 20424065, 21471389, 19295166, 19213918, 22037498, 22159094, 17569866, 21516263 | Social decision-making is arguably the most complex cognitive function performed by the human brain. This is due to two unique features of social decision-making. First, predicting the behaviors of others is extremely difficult. Second, humans often take into consideration the well-beings of others during decision-making, but this is influenced by many contextual factors. Despite such complexity, studies on the neural basis of social decision-making have made substantial progress in the last several years. They demonstrated that the core brain areas involved in reinforcement learning and valuation, such as the ventral striatum and orbitofrontal cortex, make important contribution to social decision-making. Furthermore, the contribution of brain systems implicated for theory of mind during decision-making is being elucidated. Future studies are expected to provide additional details about the nature of information channeled through these brain areas. | Animals, Brain, Choice Behavior, Decision Making, Humans, Learning, Models, Psychological, Social Behavior | null |
22,704,797 | 2013-05-22 | 2019-12-10 | 1873-6882 | Current opinion in neurobiology | How to set the switches on this thing. | Dayan Peter | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Review | null | IM | 22704797, S0959-4388(12)00099-2, 10.1016/j.conb.2012.05.011 | Reinforcement learning (RL) has become a dominant computational paradigm for modeling psychological and neural aspects of affectively charged decision-making tasks. RL is normally construed in terms of the interaction between a subject and its environment, with the former emitting actions, and the latter providing stimuli, and appetitive and aversive reinforcement. However, there is recent emphasis on redrawing the boundary between the two, with the organism constructing its own notion of reward, punishment and state, and with internal actions, such as the gating of working memory, being treated on an equal footing with external manipulation of the environment. We review recent work in this area, focusing on cognitive control. | Animals, Appetitive Behavior, Avoidance Learning, Decision Making, Humans, Models, Psychological, Reinforcement, Psychology, Reward | null |
22,704,800 | 2012-10-01 | 2012-07-23 | 1552-6259 | The Annals of thoracic surgery | Impact of early surgical treatment on postoperative neurologic outcome for active infective endocarditis complicated by cerebral infarction. | Yoshioka Daisuke, Sakaguchi Taichi, Yamauchi Takashi, Okazaki Shuhei, Miyagawa Shigeru, Nishi Hiroyuki, Yoshikawa Yasushi, Fukushima Satsuki, Saito Shunsuke, Sawa Yoshiki | eng | null | Journal Article | null | IM | 22704800, S0003-4975(12)00798-9, 10.1016/j.athoracsur.2012.04.027 | The optimal timing of surgical intervention for infective endocarditis (IE) with cerebrovascular complications remains controversial because the risk of perioperative intracranial hemorrhage is still unclear. The aim of this study was to investigate the prevalence of acute cerebral infarction (CI) in patients with IE and its hemorrhagic risk after valve operations. | Acute Disease, Adult, Aged, Cerebral Infarction, Endocarditis, Bacterial, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Time Factors, Treatment Outcome | null |
22,704,798 | 2013-02-14 | 2021-10-21 | 1750-1172 | Orphanet journal of rare diseases | A national internet-linked based database for pediatric interstitial lung diseases: the French network. | Nathan Nadia, Taam Rola Abou, Epaud Ralph, Delacourt Christophe, Deschildre Antoine, Reix Philippe, Chiron Raphaël, de Pontbriand Ulrika, Brouard Jacques, Fayon Michaël, Dubus Jean-Christophe, Giovannini-Chami Lisa, Bremont François, Bessaci Katia, Schweitzer Cyril, Dalphin Marie-Laure, Marguet Christophe, Houdouin Véronique, Troussier Françoise, Sardet Anne, Hullo Eglantine, Gibertini Isabelle, Mahloul Malika, Michon Delphine, Priouzeau Adrien, Galeron Laurie, Vibert Jean-François, Thouvenin Guillaume, Corvol Harriet, Deblic Jacques, Clement Annick | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704798, 1750-1172-7-40, 10.1186/1750-1172-7-40, PMC3458912, 20003372, 20403820, 19861431, 18957494, 22236549, 19148933, 17044090, 11854318, 15517377, 15289765, 18628224, 16641205, 17540762, 20656946, 8414740, 18057063, 20727133, 17142808, 16176405, 19422035, 11401056, 21828032, 21085204, 9565498, 19336474, 22068586, 19443464, 16473816, 16721150, 11854319, 15911458, 17267394, 18383113, 18032765, 15044640, 14989436, 20020530 | Interstitial lung diseases (ILDs) in children represent a heterogeneous group of rare respiratory disorders that affect the lung parenchyma. After the launch of the French Reference Centre for Rare Lung Diseases (RespiRare®), we created a national network and a web-linked database to collect data on pediatric ILD. | Adolescent, Child, Child, Preschool, Databases, Factual, Female, France, Government Programs, Humans, Infant, Internet, Lung Diseases, Interstitial, Male, Patient Care, Rare Diseases | null |
22,704,799 | 2012-10-01 | 2021-10-21 | 1552-6259 | The Annals of thoracic surgery | Variation in outcomes for risk-stratified pediatric cardiac surgical operations: an analysis of the STS Congenital Heart Surgery Database. | Jacobs Jeffrey Phillip, O'Brien Sean M, Pasquali Sara K, Jacobs Marshall Lewis, Lacour-Gayet François G, Tchervenkov Christo I, Austin Erle H, Pizarro Christian, Pourmoghadam Kamal K, Scholl Frank G, Welke Karl F, Gaynor J William, Clarke David R, Mayer John E, Mavroudis Constantine | eng | K08 HL103631 (NHLBI NIH HHS, United States) | Journal Article, Multicenter Study | null | IM | 22704799, S0003-4975(12)00218-4, 10.1016/j.athoracsur.2012.01.105, PMC4006082, NIHMS526118, 16928571, 22115229, 16631716, 19063780, 19837218, 15315999, 18036930, 23804682, 15568194, 20307856, 19464406 | We evaluated outcomes for groups of risk-stratified operations in The Society of Thoracic Surgeons Congenital Heart Surgery Database to provide contemporary benchmarks and examine variation between centers. | Adolescent, Benchmarking, Cardiac Surgical Procedures, Child, Databases, Factual, Female, Heart Defects, Congenital, Heart Diseases, Humans, Male, Risk Assessment, Treatment Outcome | null |
22,704,801 | 2012-11-13 | 2016-11-25 | 1552-6259 | The Annals of thoracic surgery | Open, hybrid, and endovascular treatment for aortic coarctation and postrepair aneurysm in adolescents and adults. | Roselli Eric E, Qureshi Athar, Idrees Jahanzaib, Lima Brian, Greenberg Roy K, Svensson Lars G, Pettersson Gosta | eng | null | Comparative Study, Journal Article | null | IM | 22704801, S0003-4975(12)00892-2, 10.1016/j.athoracsur.2012.04.033 | Open, hybrid, and endovascular procedures are used for grown-up patients with aortic coarctation and complications after repair, an expanding population. We sought to characterize patients and procedures, assess early and late outcomes, and describe indications to guide treatment of these complex patients. | Adolescent, Adult, Age Factors, Aged, Aneurysm, False, Aortic Coarctation, Aortography, Cardiopulmonary Bypass, Cohort Studies, Endovascular Procedures, Female, Follow-Up Studies, Humans, Male, Middle Aged, Minimally Invasive Surgical Procedures, Postoperative Complications, Recurrence, Retrospective Studies, Risk Assessment, Sex Factors, Sternotomy, Survival Rate, Time Factors, Treatment Outcome, Vascular Surgical Procedures, Young Adult | null |
22,704,803 | 2012-10-02 | 2021-10-21 | 1752-1947 | Journal of medical case reports | Urinary bladder pyogenic granuloma: a case report. | Mukai Shoichiro, Tanaka Hiroyuki, Yamasaki Kouji, Goto Takayuki, Onizuka Chie, Kamoto Toshiyuki, Kataoka Hiroaki | eng | null | Journal Article | null | null | 22704803, 1752-1947-6-149, 10.1186/1752-1947-6-149, PMC3407711, 20163837, 17509394, 16005715, 20846306, 19373418, 20627282, 10430259, 4784512, 18580491 | Although more than 100 cases of hemangioma of the urinary bladder have been reported, capillary-type hemangiomas of the bladder are rare. Pyogenic granulomas, which are common tumor-like vascular lesions of the skin and oral mucous membranes, reveal histopathological findings similar to capillary-type hemangiomas and are differentiated from ordinary hemangiomas by clinical features and etiologic factors. Little is known regarding the occurrence of pyogenic granulomas in the urinary bladder. | null | null |
22,704,804 | 2012-10-23 | 2015-06-16 | 1474-547X | Lancet (London, England) | Leukaemia cutis. | Kumar Nilay, Yadav Swetha, Reddy Vishnu, Robert Francisco | eng | null | Case Reports, Journal Article | null | IM | 22704804, S0140-6736(12)60352-3, 10.1016/S0140-6736(12)60352-3 | null | Biopsy, Female, Humans, Leukemia, Myeloid, Acute, Leukemic Infiltration, Middle Aged, Skin | null |
22,704,805 | 2013-01-03 | 2020-12-09 | 1879-1484 | Atherosclerosis | A common periodontal pathogen has an adverse association with both acute and stable coronary artery disease. | Hyvärinen Kati, Mäntylä Päivi, Buhlin Kåre, Paju Susanna, Nieminen Markku S, Sinisalo Juha, Pussinen Pirkko J | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Antibodies, Bacterial, Lipopolysaccharides | IM | 22704805, S0021-9150(12)00331-0, 10.1016/j.atherosclerosis.2012.05.021 | The aim of this study was to investigate the association between angiographically verified coronary artery disease (CAD) and salivary levels of four major periodontal pathogens. | Acute Coronary Syndrome, Aged, Aggregatibacter actinomycetemcomitans, Alveolar Bone Loss, Antibodies, Bacterial, Bacterial Load, Bacteroidetes, Chi-Square Distribution, Coronary Angiography, Coronary Artery Disease, Diagnosis, Oral, Female, Finland, Hemorrhage, Humans, Lipopolysaccharides, Logistic Models, Male, Middle Aged, Odds Ratio, Pasteurellaceae, Periodontal Diseases, Porphyromonas gingivalis, Prevotella intermedia, Real-Time Polymerase Chain Reaction, Risk Assessment, Risk Factors, Saliva, Severity of Illness Index | null |
22,704,807 | 2013-01-29 | 2012-09-14 | 1879-2456 | Waste management (New York, N.Y.) | Feasibility of incorporating treated lignins in fiberboards made from agricultural waste. | Mancera Camilo, El Mansouri Nour-Eddine, Pelach María Angels, Francesc Ferrando, Salvadó Joan | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Lignin | IM | 22704807, S0956-053X(12)00228-0, 10.1016/j.wasman.2012.05.019 | This paper studies the feasibility of incorporating treated lignins in fiberboards made from Vitis vinifera as an agricultural waste. The treated lignins are the purified Kraft lignin and the alkaline hydrolyzed Kraft lignin. V. vinifera raw material and its fibers were characterized in terms of chemical composition and the results were compared to other biomass species. The chemical composition of treated lignins shows that they have high purity compared to the lignin raw material. The lignin-V. vinifera fibreboards were produced on laboratory scale by adding powdered treated lignins to the material that had previously been steam exploded. Some of the important properties of fibreboards prepared using the treated lignins as natural adhesives were evaluated. These properties were density, thickness swelling, water absorption, modulus of elasticity, modulus of rupture, internal bond strength. The explored levels of treated lignins vary from 5% to 20%. The results showed that binderless fibreboards, fibreboards made from V. vinifera fibers and alkaline hydrolyzed Kraft lignin have weaker mechanical properties. However, the fibreboards obtained using purified Kraft lignin have good mechanical and water resistance properties which satisfy the requirements of the relevant standards specifications. | Agriculture, Construction Materials, Feasibility Studies, Lignin, Materials Testing, Vitis | null |
22,704,806 | 2013-01-03 | 2022-01-29 | 1879-1484 | Atherosclerosis | Inflammatory Ly-6C(hi) monocytes play an important role in the development of severe transplant arteriosclerosis in hyperlipidemic recipients. | Schiopu Alexandru, Nadig Satish N, Cotoi Ovidiu S, Hester Joanna, van Rooijen Nico, Wood Kathryn J | eng | 082519 (Wellcome Trust, United Kingdom); FS/12/72/29754 (British Heart Foundation, United Kingdom) | Journal Article, Research Support, Non-U.S. Gov't | Antigens, Ly, Apolipoproteins E, Biomarkers, CD11b Antigen, Ly-6C antigen, mouse, Cholesterol, Receptor, Macrophage Colony-Stimulating Factor | IM | 22704806, S0021-9150(12)00318-8, 10.1016/j.atherosclerosis.2012.05.010, PMC3423631, 19168440, 16160601, 7639327, 20577051, 2007170, 11077220, 15451805, 18427143, 12515749, 15843671, 17692781, 14987399, 16962467, 2398430, 16288760, 17884993, 17038650, 15862431, 9039919, 12871640, 9355915, 17200719, 8172851, 15093804, 15262845, 21968112, 8686767, 17200718, 17924996, 18702960 | Transplant arteriosclerosis (TA) restricts long-term survival of heart transplant recipients. Although the role of monocyte/macrophages is well established in native atherosclerosis, it has been studied to a much lesser extent in TA. Plasma cholesterol is the most important non-immunologic risk factor for development of TA but the underlying mechanisms are largely unknown. We hypothesized that monocyte/macrophages might play an important role in the pathogenesis of TA under hyperlipidemic conditions. | Animals, Antigens, Ly, Aorta, Apolipoproteins E, Arteriosclerosis, Biomarkers, CD11b Antigen, Cholesterol, Disease Models, Animal, Female, Hyperlipidemias, Inflammation, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Inbred CBA, Mice, Knockout, Monocytes, Neointima, Neutrophils, Receptor, Macrophage Colony-Stimulating Factor, Severity of Illness Index, T-Lymphocytes, Up-Regulation | null |
22,704,808 | 2013-01-29 | 2012-09-14 | 1879-2456 | Waste management (New York, N.Y.) | Life cycle assessment of TV sets in China: a case study of the impacts of CRT monitors. | Song Qingbin, Wang Zhishi, Li Jinhui, Zeng Xianlai | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704808, S0956-053X(12)00197-3, 10.1016/j.wasman.2012.05.007 | Along with the rapid increase in both production and use of TV sets in China, there is an increasing awareness of the environmental impacts related to the accelerating mass production, electricity use, and waste management of these sets. This paper aims to describe the application of life cycle assessment (LCA) to investigate the environmental performance of Chinese TV sets. An assessment of the TV set device (focusing on the Cathode Ray Tube (CRT) monitor) was carried out using a detailed modular LCA based on the international standards of the ISO 14040 series. The LCA was constructed using SimaPro software version 7.2 and expressed with the Eco-indicator' 99 life cycle impact assessment method. For a sensitivity analysis of the overall LCA results, the CML method was used in order to estimate the influence of the choice of the assessment method on the results. Life cycle inventory information was compiled by Ecoinvent 2.2 databases, combined with literature and field investigations on the current Chinese situation. The established LCA study shows that the use stage of such devices has the highest environmental impact, followed by the manufacturing stage. In the manufacturing stage, the CRT and the Printed Circuit Board (PCB) are those components contributing the most environmental impacts. During the use phase, the environmental impacts are due entirely to the methods of electricity generation used to run them, since no other aspects were taken into account for this phase. The final processing step-the end-of-life stage-can lead to a clear environmental benefit when the TV sets are processed through the formal dismantling enterprises in China. | Cathode Ray Tube, China, Electronic Waste, Environment, Recycling, Television, Waste Management | null |
22,704,809 | 2012-11-30 | 2013-11-21 | 1872-7913 | International journal of antimicrobial agents | Global transcriptional responses to triclosan exposure in Pseudomonas aeruginosa. | Chuanchuen Rungtip, Schweizer Herbert P | eng | AI51588 (NIAID NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural | Acyl Carrier Protein, Anti-Infective Agents, Local, Bacterial Proteins, RNA, Bacterial, Triclosan, Iron | IM | 22704809, S0924-8579(12)00178-1, 10.1016/j.ijantimicag.2012.04.008 | Global gene transcription was assessed by microarray experiments following treatment of a triclosan-susceptible Δ(mexAB-oprM) Pseudomonas aeruginosa strain with subinhibitory concentrations of triclosan. Expression patterns of selected genes were verified by quantitative real-time PCR analysis. The results showed that triclosan exposure had a profound effect on gene expression, affecting 44% of the genes present on the Affymetrix GeneChip(®), with 28% of genes being significantly upregulated and 16% being significantly downregulated in triclosan-treated cells. Genes encoding membrane proteins, transporters of small molecules, aspects of amino acid metabolism, and transcriptional regulators were significantly over-represented among the more strongly upregulated or downregulated genes in triclosan-treated cells. Quorum sensing-regulated genes were among the most strongly downregulated genes, presumably because of decreased acyl-acyl carrier protein pools and the resulting reduced acyl-homoserine lactone molecule synthesis. Surprisingly, iron homeostasis was completed perturbed in triclosan-exposed cells, with iron acquisition systems being strongly downregulated and iron storage systems significantly upregulated, thus mimicking conditions of excess iron. The profound perturbations of cellular metabolism via specific and global mechanisms may explain why triclosan is such a potent antimicrobial in susceptible bacteria. | Acyl Carrier Protein, Anti-Infective Agents, Local, Bacterial Proteins, Gene Expression Regulation, Bacterial, Genes, Bacterial, Homeostasis, Iron, Microbial Sensitivity Tests, Oligonucleotide Array Sequence Analysis, Pseudomonas aeruginosa, Quorum Sensing, RNA, Bacterial, Real-Time Polymerase Chain Reaction, Transcription, Genetic, Triclosan | null |
22,704,810 | 2012-12-21 | 2012-07-16 | 1879-114X | Clinical therapeutics | Treating hypertension to reduce cardiovascular risk: a Korean perspective. | Kim Kwang-Il, Kim Cheol-Ho | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704810, S0149-2918(12)00324-4, 10.1016/j.clinthera.2012.05.006 | Hypertension usually clusters with other cardiovascular risk factors; however, it has not been reported whether hypertension treatment has an impact on the awareness and treatment of other cardiovascular risk factors such as diabetes mellitus and hypercholesterolemia. | Adult, Blood Pressure, Cardiovascular Diseases, Cross-Sectional Studies, Diabetes Mellitus, Female, Health Knowledge, Attitudes, Practice, Health Surveys, Humans, Hypercholesterolemia, Hypertension, Male, Middle Aged, Obesity, Prevalence, Republic of Korea, Risk Factors | null |
22,704,811 | 2013-09-09 | 2018-12-01 | 1347-4421 | Journal of bioscience and bioengineering | Purification and characterization of an L-amino acid oxidase from Pseudomonas sp. AIU 813. | Isobe Kimiyasu, Sugawara Asami, Domon Hanako, Fukuta Yasuhisa, Asano Yasuhisa | eng | null | Journal Article | Coenzymes, Flavoproteins, Arginine, Ornithine, L-Amino Acid Oxidase, Lysine, Nitrogen | IM | 22704811, S1389-1723(12)00190-9, 10.1016/j.jbiosc.2012.04.020 | An L-amino acid oxidase was found from a newly isolated strain, Pseudomonas sp. AIU 813. This enzyme was remarkably induced by incubation with L-lysine as a nitrogen source, and efficiently purified using an affinity chromatography with L-lysine as ligand. The enzyme oxidized L-lysine, L-ornithine and L-arginine, but not other L-amino acids and d-amino acids. The oxidase activity for L-lysine was detected in a wide pH range, and its optimal was pH 7.0. In contrast, the oxidase activity for L-ornithine and L-arginine was not shown in acidic region from pH 6.5, and optimal pH for both substrates was 9.0. The enzyme was a flavoprotein and composed of two identical subunits with molecular mass of 54.5 kDa. The N-terminal amino acid sequence was similar to that of putative flavin-containing amine oxidase and putative tryptophan 2-monooxygenase, but not to that of L-amino acid oxidases. | Amino Acid Sequence, Arginine, Coenzymes, Enzyme Induction, Flavoproteins, Hydrogen-Ion Concentration, Isoelectric Point, L-Amino Acid Oxidase, Lysine, Molecular Sequence Data, Molecular Weight, Nitrogen, Ornithine, Pseudomonas, Substrate Specificity, Temperature, Time Factors | null |
22,704,813 | 2013-09-09 | 2018-12-01 | 1347-4421 | Journal of bioscience and bioengineering | Covalent immobilization of ascorbate oxidase onto polycarbonate strip for L-ascorbic acid detection. | Kannoujia Dileep Kumar, Kumar Saroj, Nahar Pradip | eng | null | Journal Article, Research Support, Non-U.S. Gov't | 1-fluoro-2-nitro-4-azidobenzene, Azides, Enzymes, Immobilized, Nitrobenzenes, Polycarboxylate Cement, polycarbonate, Ascorbate Oxidase, Ascorbic Acid | IM | 22704813, S1389-1723(12)00237-X, 10.1016/j.jbiosc.2012.05.019 | Herein, a simple and rapid method is described for detection of L-ascorbic acid by ascorbate oxidase immobilized onto polycarbonate strip pre-activated by 1-fluoro-2-nitro-4-azidobenzene in photochemical reaction. Covalent attachment of ascorbate oxidase was confirmed by XPS studies. The immobilized-ascorbate oxidase shows higher pH, thermal and storage stability in comparison to free enzyme. | Ascorbate Oxidase, Ascorbic Acid, Azides, Chemistry Techniques, Analytical, Enzymes, Immobilized, Nitrobenzenes, Polycarboxylate Cement | null |
22,704,812 | 2013-09-09 | 2020-12-09 | 1347-4421 | Journal of bioscience and bioengineering | Improvement of the growth defect in salt- and ethanol-tolerant yeast mutagenized with error-prone DNA polymerization by using backcross cell fusion. | Hayashi Kazukiyo, Yano Shuntaro, Abe Hiroko, Fujita Yasuko, Kishida Masao | eng | null | Journal Article | Ethanol, Sodium Chloride, DNA Polymerase III | IM | 22704812, S1389-1723(12)00210-1, 10.1016/j.jbiosc.2012.05.014 | Salt- and ethanol-tolerant mutants of Saccharomyces cerevisiae, isolated from the uracil-requiring mutant derived from Taiken No. 396 by proofreading-deficient DNA polymerization, showed less growth than their parent strain. The fusants, between these tolerant mutants and the lysine-requiring mutant from Taiken No. 396 obtained by the protoplast fusion, indicated improved growth. | DNA Polymerase III, Ethanol, Industrial Microbiology, Mutagenesis, Saccharomyces cerevisiae, Sodium Chloride | null |
22,704,802 | 2012-11-08 | 2022-03-31 | 0392-856X | Clinical and experimental rheumatology | Vitamin D-binding protein (group-specific component) has decreased expression in rheumatoid arthritis. | Yan Xinfeng, Zhao Yan, Pan Jihong, Fang Kehua, Wang Yuejian, Li Zhanguo, Chang Xiaotian | eng | null | Comparative Study, Journal Article, Research Support, Non-U.S. Gov't | Vitamin D-Binding Protein | IM | 22704802, 5268 | This study used a proteomic approach to screen the proteins with decreased expression in the synovial tissues of rheumatoid arthritis (RA) patients by comparing their expression profiles to that of osteoarthritis (OA) and ankylosing spondylitis (AS) patients. The result was complemented by a SNP analysis. | Adolescent, Adult, Aged, Arthritis, Rheumatoid, Cohort Studies, Female, Gene Frequency, Genotype, Humans, Linkage Disequilibrium, Male, Middle Aged, Osteoarthritis, Polymorphism, Single Nucleotide, Proteomics, Spondylitis, Ankylosing, Synovial Membrane, Vitamin D-Binding Protein, Young Adult | null |
22,704,814 | 2013-09-09 | 2018-12-01 | 1347-4421 | Journal of bioscience and bioengineering | Coreflood assay using extremophile microorganisms for recovery of heavy oil in Mexican oil fields. | Castorena-Cortés Gladys, Roldán-Carrillo Teresa, Reyes-Avila Jesús, Zapata-Peñasco Icoquih, Mayol-Castillo Martha, Olguín-Lora Patricia | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Alkanes, Hydrocarbons, Petroleum, Surface-Active Agents | IM | 22704814, S1389-1723(12)00207-1, 10.1016/j.jbiosc.2012.05.011 | A considerable portion of oil reserves in Mexico corresponds to heavy oils. This feature makes it more difficult to recover the remaining oil in the reservoir after extraction with conventional techniques. Microbial enhanced oil recovery (MEOR) has been considered as a promising technique to further increase oil recovery, but its application has been developed mainly with light oils; therefore, more research is required for heavy oil. In this study, the recovery of Mexican heavy oil (11.1°API and viscosity 32,906 mPa s) in a coreflood experiment was evaluated using the extremophile mixed culture A7, which was isolated from a Mexican oil field. Culture A7 includes fermentative, thermophilic, and anaerobic microorganisms. The experiments included waterflooding and MEOR stages, and were carried out under reservoir conditions (70°C and 9.65 MPa). MEOR consisted of injections of nutrients and microorganisms followed by confinement periods. In the MEOR stages, the mixed culture A7 produced surface-active agents (surface tension reduction 27 mN m⁻¹), solvents (ethanol, 1738 mg L⁻¹), acids (693 mg L⁻¹), and gases, and also degraded heavy hydrocarbon fractions in an extreme environment. The interactions of these metabolites with the oil, as well as the bioconversion of heavy oil fractions to lighter fractions (increased alkanes in the C₈-C₃₀ range), were the mechanisms responsible for the mobility and recovery of heavy oil from the porous media. Oil recovery by MEOR was 19.48% of the residual oil in the core after waterflooding. These results show that MEOR is a potential alternative to heavy oil recovery in Mexican oil fields. | Alkanes, Extraction and Processing Industry, Hydrocarbons, Mexico, Molecular Sequence Data, Oil and Gas Fields, Petroleum, Surface Tension, Surface-Active Agents, Thermoanaerobacter, Viscosity | null |
22,704,816 | 2013-05-20 | 2022-03-11 | 2210-741X | Clinics and research in hepatology and gastroenterology | A combination of models for end-stage liver disease and cirrhosis-related complications to predict the prognosis of liver cirrhosis. | Zhang Qiu-Bo, Chen Yin-Ting, Lian Guo-Da, Qian Chen-Chen, Chen Shao-Jie, Huang Kai-Hong | eng | null | Journal Article | null | IM | 22704816, S2210-7401(12)00133-7, 10.1016/j.clinre.2012.04.014 | The Child-Pugh score, the model for end-stage liver disease (MELD) score, and the occurrence of cirrhosis-related complications are independent prognostic predictors used in the assessment of chronic liver diseases. | Adult, Aged, Aged, 80 and over, End Stage Liver Disease, Female, Humans, Liver Cirrhosis, Male, Middle Aged, Models, Theoretical, Prognosis, Retrospective Studies, Young Adult | null |
22,704,815 | 2012-11-08 | 2013-11-21 | 1873-3700 | Phytochemistry | Effect of starvation on the distribution of positional isomers and enantiomers of triacylglycerol in the diatom Phaeodactylum tricornutum. | Rezanka Tomáš, Lukavský Jaromír, Nedbalová Linda, Kolouchová Irena, Sigler Karel | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Culture Media, Triglycerides, Eicosapentaenoic Acid | IM | 22704815, S0031-9422(12)00242-7, 10.1016/j.phytochem.2012.05.021 | The diatom Phaeodactylum tricornutum was cultivated in a standard medium and under sulfur, silicon, nitrogen and phosphorus starvation and its triacylglycerols (TAGs) were analyzed by RP-HPLC/MS-APCI. Nearly 100 molecular species of polyunsaturated TAGs were identified. RP-HPLC was used to isolate positional isomers of TAGs, which were further separated by chiral HPLC. First eluted were those TAGs that have an eicosapentaenoic acid moiety in the sn-1 position. The ratios of symmetrical to asymmetrical TAGs in P. tricornutum were affected under sulfur-, nitrogen-, phosphorus- and silica-starvation, i.e. in cultivations involving cells in nutrient stress. The ratios of positional TAGs and also the proportions of enantiomers were changed. The ratios of symmetrical to asymmetrical TAGs in the control and under N- and P-starvation were very close. In the control, the ratio of 1,2-dipalmitoyl-3-eicosapentaenoyl-rac-glycerol to 1,3-dipalmitoyl-2-eicosapentaenoyl-rac-glycerol was 3:1 and the ratio of 1,2-dieicosapentaenoyl-3-palmitoyl-rac-glycerol to 1,3-dieicosapentaenoyl-2-palmitoyl-rac-glycerol was 9:1. Under N-starvation the ratios were reversed irrespective of the presence or absence of silicate in the medium. A similar pattern was found in P- and S-starvation. | Culture Media, Diatoms, Eicosapentaenoic Acid, Stereoisomerism, Triglycerides | null |
22,704,818 | 2013-05-20 | 2012-12-03 | 2210-741X | Clinics and research in hepatology and gastroenterology | Endoscopic closure of gastrointestinal defects with an over-the-scope clip device. A case series and review of the literature. | Dişibeyaz Selçuk, Köksal Aydin Şeref, Parlak Erkan, Torun Serkan, Şaşmaz Nurgül | eng | null | Journal Article, Review | null | IM | 22704818, S2210-7401(12)00134-9, 10.1016/j.clinre.2012.04.015 | The over-the-scope clip (OTSC) is a novel endoscopic tool used in the non surgical treatment of gastrointestinal perforations, fistula, and anastomotic leaks. | Adult, Aged, Anastomotic Leak, Endoscopy, Gastrointestinal, Equipment Design, Female, Humans, Intestinal Fistula, Intestinal Perforation, Male, Middle Aged, Young Adult | null |
22,704,817 | 2014-01-24 | 2013-04-19 | 2210-741X | Clinics and research in hepatology and gastroenterology | Determinants of participation in organized colorectal cancer screening in Isère (France). | Poncet Florence, Delafosse Patricia, Seigneurin Arnaud, Exbrayat Catherine, Colonna Marc | eng | null | Journal Article, Research Support, Non-U.S. Gov't | null | IM | 22704817, S2210-7401(12)00130-1, 10.1016/j.clinre.2012.04.011 | In France, participation in organized colorectal cancer screening remains low. The objective of this study was to identify the determinants of participation in colorectal cancer screening in Isère, a French administrative entity. | Age Distribution, Aged, Colorectal Neoplasms, Female, France, Humans, Insurance, Health, Logistic Models, Male, Mass Screening, Middle Aged, Patient Participation, Sex Distribution, Social Class | null |
22,704,819 | 2012-10-22 | 2015-11-19 | 1879-1190 | Journal of the American College of Surgeons | Quantitative comparison and analysis of species-specific wound biofilm virulence using an in vivo, rabbit-ear model. | Seth Akhil K, Geringer Matthew R, Galiano Robert D, Leung Kai P, Mustoe Thomas A, Hong Seok J | eng | null | Comparative Study, Journal Article, Research Support, U.S. Gov't, Non-P.H.S. | Biomarkers, Inflammation Mediators, Polysaccharides, Bacterial, RNA, Bacterial, RNA, Messenger, exopolysaccharide, Pseudomonas | IM | 22704819, S1072-7515(12)00417-6, 10.1016/j.jamcollsurg.2012.05.028 | Although bacterial biofilm is recognized as an important contributor to chronic wound pathogenesis, differences in biofilm virulence between species have never been studied in vivo. | Animals, Bacterial Load, Biofilms, Biomarkers, Ear, External, Inflammation Mediators, Klebsiella pneumoniae, Microscopy, Electron, Scanning, Models, Animal, Polysaccharides, Bacterial, Pseudomonas aeruginosa, RNA, Bacterial, RNA, Messenger, Rabbits, Reverse Transcriptase Polymerase Chain Reaction, Soft Tissue Injuries, Staphylococcus aureus, Virulence, Wound Healing | null |
22,704,820 | 2012-10-22 | 2022-03-21 | 1879-1190 | Journal of the American College of Surgeons | Ablation of perivascular hepatic malignant tumors with irreversible electroporation. | Kingham T Peter, Karkar Ami M, D'Angelica Michael I, Allen Peter J, Dematteo Ronald P, Getrajdman George I, Sofocleous Constantinos T, Solomon Stephen B, Jarnagin William R, Fong Yuman | eng | null | Evaluation Study, Journal Article | null | IM | 22704820, S1072-7515(12)00353-5, 10.1016/j.jamcollsurg.2012.04.029 | Ablation is increasingly used to treat primary and secondary liver cancer. Ablation near portal pedicles and hepatic veins is challenging. Irreversible electroporation (IRE) is a new ablation technique that does not rely on heat and, in animals, appears to be safe and effective when applied near hepatic veins and portal pedicles. This study evaluated the safety and short-term outcomes of IRE to ablate perivascular malignant liver tumors. | Ablation Techniques, Adult, Aged, Aged, 80 and over, Electroporation, Female, Follow-Up Studies, Hepatic Veins, Humans, Intraoperative Complications, Liver Neoplasms, Male, Middle Aged, Neoplasm Recurrence, Local, Portal Vein, Postoperative Complications, Retrospective Studies, Treatment Outcome | null |
22,704,823 | 2012-11-28 | 2022-12-07 | 1878-0539 | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | Facing the World: audit of activity 2002-2010. | Hachach-Haram N, Benyon S L, Eccles S J, Kirkpatrick W N A, Kelly M, Waterhouse N | eng | null | Comparative Study, Evaluation Study, Journal Article | null | IM | 22704823, S1748-6815(12)00237-9, 10.1016/j.bjps.2012.04.029 | Craniofacial anomalies, although uncommon, can have considerable effects on the individual, their family and society.(1-4) They carry with them a large morbidity and require a highly specialized, multidisciplinary approach to treatment.(5) Facing the World (FTW), was founded in 2002, to offer facial reconstructive surgery to children with complex, craniofacial anomalies with no prospect of local treatment, from developing countries anywhere in the world. | Adolescent, Child, Child, Preschool, Congenital Abnormalities, Craniofacial Abnormalities, Developing Countries, Female, Fund Raising, Global Health, Humans, Infant, Male, Medical Audit, Medical Missions, Medically Underserved Area, Plastic Surgery Procedures, United Kingdom, Young Adult | null |
22,704,824 | 2012-11-28 | 2012-09-17 | 1878-0539 | Journal of plastic, reconstructive & aesthetic surgery : JPRAS | Pixie ear deformity following rhytidectomy: 'prevention is better than cure'. | Ghali S, Pagkalos V A, Hedén P | eng | null | Letter | null | IM | 22704824, S1748-6815(12)00226-4, 10.1016/j.bjps.2012.04.023 | null | Ear Deformities, Acquired, Ear, External, Female, Follow-Up Studies, Humans, Reoperation, Rhytidoplasty, Risk Assessment, Wound Healing | null |
22,704,822 | 2012-10-25 | 2022-03-30 | 0870-2551 | Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology | Fulminant myocarditis associated with pandemic H1N1 influenza A virus. | Cabral Marta, Brito Maria J, Conde Marta, Oliveira Mário, Ferreira Gonçalo C | eng | null | Case Reports, Journal Article | null | IM | 22704822, S0870-2551(12)00113-8, 10.1016/j.repc.2011.11.012 | Fulminant myocarditis associated with influenza A virus is exceedingly rare, with only a few cases reported in the literature. We describe a previously healthy 10-year-old boy, with a three-day history of flu-like symptoms without antiviral treatment. He was hospitalized with dehydration and hypothermia in the context of persistent vomiting, when he suddenly developed heart failure secondary to fulminant myocarditis. Despite aggressive management, including circulatory support and cardiopulmonary resuscitation measures, the patient died of cardiogenic shock. The postmortem histopathology was compatible with a multisystem viral infection with myocarditis and pulmonary involvement, and H1N1v polymerase chain reaction was positive. The prevalence of influenza-associated fulminant myocarditis remains unknown. Findings reported in the literature raise the possibility that the novel H1N1 influenza A virus is more commonly associated with a severe form of myocarditis than previously encountered influenza strains. | Child, Fatal Outcome, Humans, Influenza A Virus, H1N1 Subtype, Influenza, Human, Male, Myocarditis, Pandemics | null |
22,704,825 | 2012-11-16 | 2014-11-20 | 1873-2380 | Journal of biomechanics | Tribological characteristics of healthy tendon. | Theobald Peter S, Dowson Duncan, Khan Ilyas M, Jones Michael D | eng | null | Journal Article | null | IM | 22704825, S0021-9290(12)00274-6, 10.1016/j.jbiomech.2012.05.005 | Tendons transfer muscular forces efficiently and painlessly, facilitating joint motion. Whilst the tribology of articular cartilage is constantly explored, a poorer understanding remains of tendon lubrication and friction. This study reports experimental data describing the tribological characteristics of tendon and its surrounding tissue, before presenting an arithmetic solution to facilitate numerical modelling. The experimental characteristics of the tensile (i.e. mid-substance) and compressive (i.e. fibrocartilaginous) regions of bovine flexor tendon were investigated using a pin-on-plate tribometer, with immunofluroscence analysis describing the relative intensity and distribution of surface-bound lubricin. Arithmetic analysis considering the digital extensor tendon determined that, in physiological conditions, the tensile tendon region was able to generate elastohydrodynamic lubrication (EHL). The equivalent region of compressive tendon exhibited a higher intensity of surface-bound lubricin which, it is hypothesised, serves to minimise the increased frictional resistance due to generating only mixed or boundary lubrication regimes. Arithmetic analysis indicates that, given a more favourable biomechanical environment, this region can also generate EHL. Whilst acknowledging the limitations of transferring data from an animal model to a clinical environment, by providing the first data and equations detailing the film thicknesses and lubrication regime for these two tendon regions it is hoped that clinicians, engineers and scientists can consider improved clinical strategies to tackle both tendinopathy and tendon rupture. | Animals, Cattle, Compressive Strength, Computer Simulation, Elastic Modulus, Friction, In Vitro Techniques, Lubrication, Models, Biological, Tendons, Tensile Strength | null |
22,704,827 | 2013-02-26 | 2012-09-17 | 1872-9126 | Applied ergonomics | Effect of human link length determination on posture reconstruction. | Gragg Jared, Yang Jingzhou James, Cloutier Aimee, Pena Pitarch Esteban | eng | null | Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S. | null | IM | 22704827, S0003-6870(12)00066-X, 10.1016/j.apergo.2012.05.003 | Motion capture experiment results are often used as a means of validation for digital human simulations. Motion capture results are marker positions and joint centers in Cartesian space. However, joint angles are more intuitive and easy to understand compared to marker or joint center positions. Posture reconstruction algorithms are used to map Cartesian space to joint space by re-creating experimental postures with simulation models. This allows for direct comparison between the experimental results and digital human simulations. Besides the inherent experimental errors from motion capture system, one source of simulation error is the determination of the link lengths to be used in the simulation model. The link length errors can propagate through all simulation results. Therefore, it is critical to eliminate the link length errors. The objective of this study is to determine the best method of determining link lengths for the simulation model to best match the model to the experiment results containing errors. Specifically, the way that the link lengths are calculated in the posture reconstruction process from motion capture data has a significant effect on the recreated posture for the simulation model. Three link length calculation methods (experimental-average method, trial-specific method, and T-pose method) are developed and compared to a benchmark method (frame-specific method) for calculating link lengths. The results indicate that using the trial-specific method is the most accurate method when referring to calculating frame-specific link lengths. | Computer Simulation, Female, Fiducial Markers, Humans, Joints, Male, Motion, Posture, Time and Motion Studies, Young Adult | null |
22,704,826 | 2012-11-30 | 2021-10-21 | 1873-2380 | Journal of biomechanics | Micromechanics of the human vertebral body for forward flexion. | Yang Haisheng, Nawathe Shashank, Fields Aaron J, Keaveny Tony M | eng | R01 AR043784 (NIAMS NIH HHS, United States); AR43784 (NIAMS NIH HHS, United States) | Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S. | Polymethyl Methacrylate | IM | 22704826, S0021-9290(12)00325-9, 10.1016/j.jbiomech.2012.05.044, PMC3415303, NIHMS383404, 9755038, 2929278, 20362704, 10397920, 19364678, 18246009, 14555280, 15165876, 16418787, 10633263, 20838942, 19465166, 7112236, 15087801, 16038915, 20817162, 11462085, 2035348, 10450408, 16904959, 19049912, 10751296, 7917579, 21748426, 12365788, 7852443, 7657676, 7280815, 17643362, 16198356, 15003798, 7962011, 3711133, 18786670, 16094273, 17229596, 20362251, 15564916, 8945653, 7167831, 20462582, 10788851, 20110846, 21805360, 2373719, 16939399, 20715186, 12757797, 3768199, 15183453 | To provide mechanistic insight into the etiology of osteoporotic wedge fractures, we investigated the spatial distribution of tissue at the highest risk of initial failure within the human vertebral body for both forward flexion and uniform compression loading conditions. Micro-CT-based linear elastic finite element analysis was used to virtually load 22 human T9 vertebral bodies in either 5° of forward flexion or uniform compression; we also ran analyses replacing the simulated compliant disc (E=8 MPa) with stiff polymethylmethacrylate (PMMA, E=2500 MPa). As expected, we found that, compared to uniform compression, forward flexion increased the overall endplate axial load on the anterior half of the vertebra and shifted the spatial distribution of high-risk tissue within the vertebra towards the anterior aspect of the vertebral body. However, despite that shift, the high-risk tissue remained primarily within the central regions of the trabecular bone and endplates, and forward flexion only slightly altered the ratio of cortical-to-trabecular load sharing at the mid-vertebral level (mean±SD for n=22: 41.3±7.4% compression; 44.1±8.2% forward flexion). When the compliant disc was replaced with PMMA, the anterior shift of high-risk tissue was much more severe. We conclude that, for a compliant disc, a moderate degree of forward flexion does not appreciably alter the spatial distribution of stress within the vertebral body. | Compressive Strength, Humans, Intervertebral Disc, Models, Biological, Osteoporosis, Polymethyl Methacrylate, Radiography, Spinal Fractures, Weight-Bearing | null |
22,704,828 | 2012-11-05 | 2013-11-21 | 1873-2976 | Bioresource technology | Preparation of sludge derived magnetic porous carbon and their application in Fenton-like degradation of 1-diazo-2-naphthol-4-sulfonic acid. | Gu Lin, Zhu Nanwen, Zhou Pin | eng | null | Journal Article, Research Support, Non-U.S. Gov't | Azo Compounds, Fenton's reagent, Magnetite Nanoparticles, Naphthalenesulfonates, Sewage, Sulfonic Acids, Carbon, Hydrogen Peroxide, Iron | IM | 22704828, S0960-8524(12)00857-7, 10.1016/j.biortech.2012.05.102 | A magnetic porous carbon containing Fe(3)O(4) (FPC) has been synthesized by a novel activation and carbonization process of sewage sludge without extra addition of ferric ions. Properties of FPC carbonized at 600, 800 and 1000 °C were studied using N(2) adsorption and desorption isotherms, X-ray diffraction (XRD), scanning electron microscopy (SEM) and vibrating sample magnetometer. The results indicate that FPC carbonized at 600 °C has a superior porous structure and high pore volume (0.504 mL/g). Further study found that Fe(3)O(4) is dominating in the presence of iron in FPC carbonized at 600 °C. The resulting chars shows higher catalytic activity in 1-diazo-2-naphthol-4-sulfonic acid (1,2,4-Acid) oxidation than commercial Fe(3)O(4) MNPs. The 1,2,4-Acid and TOC removal efficiency can reach 96.6% and 87.2% after 260 min Fenton-like treatment. The mechanism in FPC-H(2)O(2) system may include a Haber-Weiss type reaction between the active sites (e.g. Fe(3)O(4)) in FPC and hydrogen peroxide. | Azo Compounds, Carbon, Hydrogen Peroxide, Hydrogen-Ion Concentration, Iron, Magnetics, Magnetite Nanoparticles, Naphthalenesulfonates, Porosity, Recycling, Sewage, Sulfonic Acids, Temperature | null |
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https://ftp.ncbi.nlm.nih.gov/pubmed/baseline/
2. 2023 data sources
https://github.com/jacobvsdanniel/pubmedkb_web
*We processed all 35M PubMed citations dumped on 2023/02/17.
https://drive.google.com/file/d/17AUaMe0w3xJq3rr0Njs1tok2y3RS5tQ2/view
3. 2025 data sources
https://www.nmdc.cn/datadownload
download.py ： need monthly update
process_meatadata.py : process xml to csv
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