ibm/otter_dude

Otter DUDe Dataset Card

Otter DUDe includes 1,452,568 instances of drug-target interactions.

Dataset details

DUDe

DUDe comprises a collection of 22,886 active compounds and their corresponding affinities towards 102 targets. For our study, we utilized a preprocessed version of the DUDe, which includes 1,452,568 instances of drug-target interactions. To prevent any data leakage, we eliminated the negative interactions and the overlapping triples with the TDC DTI dataset. As a result, we were left with a total of 40,216 drug-target interaction pairs.

Original dataset:

• Citation: Samuel Sledzieski, Rohit Singh, Lenore Cowen, and Bonnie Berger. Adapting protein language models for rapid dti prediction. bioRxiv, pages 2022–11, 2022

Paper or resources for more information:

• GitHub Repo
• Paper

License:

MIT

Where to send questions or comments about the dataset:

• GitHub Repo

Models trained on Otter UBC

• ibm/otter_dude_classifier
• ibm/otter_dude_distmult
• ibm/otter_dude_transe