Shishir1807/test_drug · Datasets at Hugging Face

instruction stringclasses 1 value	input stringlengths 53 318	output stringlengths 4 72 ⌀
Identify mentioned drugs from the abstract title	Baseline GP2 immune response as an independent prognostic factor in a phase IIb study evaluating HER2/neu peptide GP2 (GLSI-100) versus. GM-CSF alone after adjuvant trastuzumab in HER2-positive women with breast cancer.	GLSI-100;;GM-CSF
Identify mentioned drugs from the abstract title	Development of radiolabelled plerixafor as a theranostic tool for malignant lymphomas	Plerixafor
Identify mentioned drugs from the abstract title	12-year trend in utilization of IVIG and plasmapheresis following acute myasthenia exacerbation and myasthenic crisis in the United States and their association with outcome.	IVIG
Identify mentioned drugs from the abstract title	Deep Immune Profiling in Multiple Myeloma at Diagnosis and Under Lenalidomide Maintenance Therapy	Lenalidomide
Identify mentioned drugs from the abstract title	Anlotinib plus chemotherapy as neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer: A prospective, single-arm, single-center, phase II clinical study.	anlotinib
Identify mentioned drugs from the abstract title	Assessment of Dose Proportionality of Three Dose Strengths (6 mg, 12 mg and 24 mg) over the Clinical Dose Range (6-48 mg) of the Newly Developed Once-Daily Extended Release Tablet Formulation of Deutetrabenazine	Deutetrabenazine
Identify mentioned drugs from the abstract title	Apatinib Combined With Irinotecan in the Treatment of Small Cell Lung Cancer: A Phase 2, Single-Arm, Prospective Study	Apatinib;;Irinotecan
Identify mentioned drugs from the abstract title	CISH gene-knockout anti-CD70-CAR NK cells demonstrate potent anti-tumor activity against solid tumor cell lines and provide partial resistance to tumor microenvironment inhibition	Anti-CD70-CAR NK Cell
Identify mentioned drugs from the abstract title	A Retrospective Comparison of Survival Outcomes in EGFR-mutated, NSCLC Patients on Osimertinib +/- Brain Metastases	Osimertinib
Identify mentioned drugs from the abstract title	Cisplatin versus mitomycin plus fluoropyrimidine and radiation for localized squamous cell carcinoma of the anus (SCCA) - final results of GTG-LACOG 1318 real world data study	Cisplatin;;Mitomycin
Identify mentioned drugs from the abstract title	CCRL2 affects the sensitivity of MDS and secondary AML to azacitidine	Azacitidine
Identify mentioned drugs from the abstract title	A Study of ALPN-202, a PD-L1-dependent CD28 costimulator and dual checkpoint inhibitor, in combination with pembrolizumab in patients with advanced malignancies	ALPN-202;;Pembrolizumab
Identify mentioned drugs from the abstract title	A common gut commensal utilizes tryptophan to promote cancer via the aryl hydrocarbon receptor	Tryptophan
Identify mentioned drugs from the abstract title	Adjuvant chemotherapy in ypStage III locally advanced rectal cancer after neoadjuvant treatment with an oxaliplatin-based regimen.	Oxaliplatin
Identify mentioned drugs from the abstract title	Brentuximab Vedotin Plus ESHAP (BRESHAP) Versus ESHAP As Salvage Strategy for Patients with Primary Refractory or Relapsed Classical Hodgkin's Lymphoma. Preliminary Results from the Breselibet Prospective Clinical Trial	Brentuximab Vedotin;;ESHAP;;ESHAP
Identify mentioned drugs from the abstract title	A phase 2 study of neoadjuvant lenvatinib in locally advanced invasive thyroid cancer.	Lenvatinib
Identify mentioned drugs from the abstract title	A WT1 oral cancer vaccine using a Bifidobactrerium vector suppresses growth of anti-PD-1 antibody-resistant mouse bladder tumor	WT1 Cancer Vaccine
Identify mentioned drugs from the abstract title	3-year update of neoadjuvant atezolizumab + chemotherapy in patients with resectable non-small cell lung cancer	Atezolizumab
Identify mentioned drugs from the abstract title	Degree Of Cell Packing Of Cryopreserved At -80oC Hematopoietic Stem Cells Does Not Affect Their Viability And Hematologic Recovery Of Transplanted Myeloma Patients	Hematopoietic Stem Cell
Identify mentioned drugs from the abstract title	CCTG PR21: A randomized phase II study of [177lu]lu-PSMA-617 verus docetaxel in patients with metastatic castration-resistant prostate cancerand PSMA-positive disease (NCT04663997).	[177-Lu]Lu-PSMA-617;;Docetaxel
Identify mentioned drugs from the abstract title	A Phase 1, First in Human (FIH) study of autologous macrophages containing an anti-HER2 chimeric antigen receptor (CAR) in participants with HER2 overexpressing solid tumors.	Anti-HER2 CAR Macrophage
Identify mentioned drugs from the abstract title	CD8 T cell-melanoma cell interactions in response and resistance to ipilimumab plus nivolumab: Biopsy analysis of SWOG S1616	Ipilimumab;;Nivolumab
Identify mentioned drugs from the abstract title	Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)	Carfilzomib;;Dexamethasone;;Elotuzumab;;Lenalidomide
Identify mentioned drugs from the abstract title	Biomarkers of Clinical Resistance to Decitabine and Venetoclax Therapy Inferred By Transcriptome and Methylation Analyses	Decitabine;;Venetoclax
Identify mentioned drugs from the abstract title	Beyond PACIFIC: Real-world outcomes of adjuvant durvalumab according to treatment received and PD-L1 expression	Durvalumab
Identify mentioned drugs from the abstract title	Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party	Fludarabine;;Melphalan;;Thiotepa;;BCNA;;Fludarabine;;Melphalan;;Thiotepa
Identify mentioned drugs from the abstract title	ARTO trial (NCT03449719), a randomized phase II trial enrolling oligometastatic castration-resistant prostate cancer patients treated with first-line abiraterone acetate with or without stereotactic body radiation therapy: Preliminary results comprehensive of biochemical outcomes and circulating tumor cells analysis.	Abiraterone Acetate
Identify mentioned drugs from the abstract title	Updates on Abstract 388570: Landscape of Pathogenic Germline Variants in Patients with Lung Cancer.	null
Identify mentioned drugs from the abstract title	A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity	Doxorubicin
Identify mentioned drugs from the abstract title	Adherence to and patient satisfaction with the combination therapy of exemestane and everolimus in postmenopausal women with HR+ HER2- advanced breast cancer: Results from the IPSOC-mamma study	Everolimus;;Exemestane
Identify mentioned drugs from the abstract title	Cannabidiol in anxiety research – a translational integration of preclinical and clinical studies	Cannabidiol
Identify mentioned drugs from the abstract title	Delay of Aspirin Administration in patients after Stroke Code Activation, who are not candidates for tissue Plasminogen Activator (t-PA) or Mechanical Thrombectomy (MT) pre- and post-COVID pandemic.	Aspirin
Identify mentioned drugs from the abstract title	A phase 1b study of nivolumab in patients with autoimmune disorders and advanced malignancies (AIM-NIVO)	NIVO;;Nivolumab
Identify mentioned drugs from the abstract title	Desmopressin is twice effective in females: A systematic review and meta-analysis on medical treatment of nocturia	Desmopressin
Identify mentioned drugs from the abstract title	Clinical and microbiological outcomes for Enterobacterales uropathogens in the Phase 3 ADAPT-PO Study of oral tebipenem pivoxil hydrobromide	Tebipenem Pivoxil Hydrobromide
Identify mentioned drugs from the abstract title	A randomized, pre-surgical study to investigate the biological effects of AZD9833 doses in women with ER-positive HER2-negative primary breast cancer (SERENA-3)	AZD-9833
Identify mentioned drugs from the abstract title	Bms-986158, A Potent Bet Inhibitor, As Monotherapy And In Combination With Ruxolitinib Or Fedratinib In Intermediate- Or High-Risk Myelofibrosis (Mf): Results From A Phase 1/2 Study	BMS-986158;;Fedratinib;;Ruxolitinib
Identify mentioned drugs from the abstract title	ASTX660, a non-peptidomimetic antagonist of cIAP1/2 and XIAP, enhances immune mediated tumor killing and induction of immunogenic cell death	ASTX-660
Identify mentioned drugs from the abstract title	ARTISTRY-1: Nemvaleukin alfa monotherapy and in combination with pembrolizumab in patients (pts) with advanced solid tumors.	Nemvaleukin Alfa;;Pembrolizumab
Identify mentioned drugs from the abstract title	BATF3/MYC axis drives hyper-proliferation of TET2 deficient CAR T cells	CAR T-cell
Identify mentioned drugs from the abstract title	Activity of OSE-2101 in HLA-A2+ non-small cell lung cancer (NSCLC) patients after failure to immune checkpoint inhibitors (IO): Final results of Phase 3 Atalante-1 randomised trial	OSE-2101
Identify mentioned drugs from the abstract title	A Phase I Study of CD19 Chimeric Antigen Receptor-T Cells Generated By the PiggyBac Transposon Vector for Acute Lymphoblastic Leukemia	CD19 CAR T-Cell
Identify mentioned drugs from the abstract title	An Open-Label, Multicenter, Phase 1/2 Clinical Trial of RP1 as a Single Agent and in Combination with Nivolumab in Patients with Solid Tumors [IGNYTE]	RP1;;Nivolumab
Identify mentioned drugs from the abstract title	Adverse events and estimated costs with the combination of ipilimumab and nivolumab in metastatic melanoma patients.	Ipilimumab;;Nivolumab
Identify mentioned drugs from the abstract title	A Phase 1B/2 Study Of Tp-0903 And Decitabine Targeting Mutant Tp53 And/Or Complex Karyotype In Patients With Untreated Acute Myeloid Leukemia (Aml) >= Age 60 Years: Final Results	Decitabine;;TP-0903
Identify mentioned drugs from the abstract title	D3L-001, a novel bispecific antibody targeting HER2 and CD47, demonstrates potent preclinical efficacy in solid tumors.	D3L-001
Identify mentioned drugs from the abstract title	Chemotherapy and bevacizumab prescription in routine management of metastatic colorectal cancer in Uruguay: Is clinical practice following the evidence?	Bevacizumab
Identify mentioned drugs from the abstract title	Allo-Hct In Myelofibrosis - Current And Future Trends	ALLO
Identify mentioned drugs from the abstract title	A functional approach to identifying and engineering TCRs results in highly-potent and specific TCRs for TCR-T cell therapy	TCR-T Cell
Identify mentioned drugs from the abstract title	The Role Of Treatment Strategy In Reducing The Disability Risk In Multiple Sclerosis	null
Identify mentioned drugs from the abstract title	68Ga-PSMA PET radiomics for the prediction of post-surgical ISUP grade in primary prostate cancer patients	68Ga-PSMA
Identify mentioned drugs from the abstract title	CRISPR/Cas9 gene-edited, allogeneic anti-CD83 CAR-T cells demonstrate potent activity in GvHD and AML tumor models	Anti-CD83 CAR-T Cell
Identify mentioned drugs from the abstract title	Anlotinib plus chemotherapy as first-line therapy for gastrointestinal tumor patients with unresectable liver metastasis: A multicenter, multicohort clinical trial (ALTER-G-001).	Anlotinib

Identify mentioned drugs from the abstract title

Baseline GP2 immune response as an independent prognostic factor in a phase IIb study evaluating HER2/neu peptide GP2 (GLSI-100) versus. GM-CSF alone after adjuvant trastuzumab in HER2-positive women with breast cancer.

GLSI-100;;GM-CSF

Identify mentioned drugs from the abstract title

Development of radiolabelled plerixafor as a theranostic tool for malignant lymphomas

Plerixafor

Identify mentioned drugs from the abstract title

12-year trend in utilization of IVIG and plasmapheresis following acute myasthenia exacerbation and myasthenic crisis in the United States and their association with outcome.

IVIG

Identify mentioned drugs from the abstract title

Deep Immune Profiling in Multiple Myeloma at Diagnosis and Under Lenalidomide Maintenance Therapy

Lenalidomide

Identify mentioned drugs from the abstract title

Anlotinib plus chemotherapy as neoadjuvant treatment of high-risk, early-stage triple-negative breast cancer: A prospective, single-arm, single-center, phase II clinical study.

anlotinib

Identify mentioned drugs from the abstract title

Assessment of Dose Proportionality of Three Dose Strengths (6 mg, 12 mg and 24 mg) over the Clinical Dose Range (6-48 mg) of the Newly Developed Once-Daily Extended Release Tablet Formulation of Deutetrabenazine

Deutetrabenazine

Identify mentioned drugs from the abstract title

Apatinib Combined With Irinotecan in the Treatment of Small Cell Lung Cancer: A Phase 2, Single-Arm, Prospective Study

Apatinib;;Irinotecan

Identify mentioned drugs from the abstract title

CISH gene-knockout anti-CD70-CAR NK cells demonstrate potent anti-tumor activity against solid tumor cell lines and provide partial resistance to tumor microenvironment inhibition

Anti-CD70-CAR NK Cell

Identify mentioned drugs from the abstract title

A Retrospective Comparison of Survival Outcomes in EGFR-mutated, NSCLC Patients on Osimertinib +/- Brain Metastases

Osimertinib

Identify mentioned drugs from the abstract title

Cisplatin versus mitomycin plus fluoropyrimidine and radiation for localized squamous cell carcinoma of the anus (SCCA) - final results of GTG-LACOG 1318 real world data study

Cisplatin;;Mitomycin

Identify mentioned drugs from the abstract title

CCRL2 affects the sensitivity of MDS and secondary AML to azacitidine

Azacitidine

Identify mentioned drugs from the abstract title

A Study of ALPN-202, a PD-L1-dependent CD28 costimulator and dual checkpoint inhibitor, in combination with pembrolizumab in patients with advanced malignancies

ALPN-202;;Pembrolizumab

Identify mentioned drugs from the abstract title

A common gut commensal utilizes tryptophan to promote cancer via the aryl hydrocarbon receptor

Tryptophan

Identify mentioned drugs from the abstract title

Adjuvant chemotherapy in ypStage III locally advanced rectal cancer after neoadjuvant treatment with an oxaliplatin-based regimen.

Oxaliplatin

Identify mentioned drugs from the abstract title

Brentuximab Vedotin Plus ESHAP (BRESHAP) Versus ESHAP As Salvage Strategy for Patients with Primary Refractory or Relapsed Classical Hodgkin's Lymphoma. Preliminary Results from the Breselibet Prospective Clinical Trial

Brentuximab Vedotin;;ESHAP;;ESHAP

Identify mentioned drugs from the abstract title

A phase 2 study of neoadjuvant lenvatinib in locally advanced invasive thyroid cancer.

Lenvatinib

Identify mentioned drugs from the abstract title

A WT1 oral cancer vaccine using a Bifidobactrerium vector suppresses growth of anti-PD-1 antibody-resistant mouse bladder tumor

WT1 Cancer Vaccine

Identify mentioned drugs from the abstract title

3-year update of neoadjuvant atezolizumab + chemotherapy in patients with resectable non-small cell lung cancer

Atezolizumab

Identify mentioned drugs from the abstract title

Degree Of Cell Packing Of Cryopreserved At -80oC Hematopoietic Stem Cells Does Not Affect Their Viability And Hematologic Recovery Of Transplanted Myeloma Patients

Hematopoietic Stem Cell

Identify mentioned drugs from the abstract title

CCTG PR21: A randomized phase II study of [177lu]lu-PSMA-617 verus docetaxel in patients with metastatic castration-resistant prostate cancerand PSMA-positive disease (NCT04663997).

[177-Lu]Lu-PSMA-617;;Docetaxel

Identify mentioned drugs from the abstract title

A Phase 1, First in Human (FIH) study of autologous macrophages containing an anti-HER2 chimeric antigen receptor (CAR) in participants with HER2 overexpressing solid tumors.

Anti-HER2 CAR Macrophage

Identify mentioned drugs from the abstract title

CD8 T cell-melanoma cell interactions in response and resistance to ipilimumab plus nivolumab: Biopsy analysis of SWOG S1616

Ipilimumab;;Nivolumab

Identify mentioned drugs from the abstract title

Central Memory T-Cell Differentiation Correlates with Depth of Response in Relapsed/Refractory Multiple Myeloma Patients Receiving Elotuzumab in Combination with Carfilzomib, Lenalidomide and Dexamethasone (Elo-KRd)

Carfilzomib;;Dexamethasone;;Elotuzumab;;Lenalidomide

Identify mentioned drugs from the abstract title

Biomarkers of Clinical Resistance to Decitabine and Venetoclax Therapy Inferred By Transcriptome and Methylation Analyses

Decitabine;;Venetoclax

Identify mentioned drugs from the abstract title

Beyond PACIFIC: Real-world outcomes of adjuvant durvalumab according to treatment received and PD-L1 expression

Durvalumab

Identify mentioned drugs from the abstract title

Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party

Fludarabine;;Melphalan;;Thiotepa;;BCNA;;Fludarabine;;Melphalan;;Thiotepa

Identify mentioned drugs from the abstract title

ARTO trial (NCT03449719), a randomized phase II trial enrolling oligometastatic castration-resistant prostate cancer patients treated with first-line abiraterone acetate with or without stereotactic body radiation therapy: Preliminary results comprehensive of biochemical outcomes and circulating tumor cells analysis.

Abiraterone Acetate

Identify mentioned drugs from the abstract title

Updates on Abstract 388570: Landscape of Pathogenic Germline Variants in Patients with Lung Cancer.

null

Identify mentioned drugs from the abstract title

A switch in mechanism of action attenuates doxorubicin-mediated cardiotoxicity

Doxorubicin

Identify mentioned drugs from the abstract title

Adherence to and patient satisfaction with the combination therapy of exemestane and everolimus in postmenopausal women with HR+ HER2- advanced breast cancer: Results from the IPSOC-mamma study

Everolimus;;Exemestane

Identify mentioned drugs from the abstract title

Cannabidiol in anxiety research – a translational integration of preclinical and clinical studies

Cannabidiol

Identify mentioned drugs from the abstract title

Delay of Aspirin Administration in patients after Stroke Code Activation, who are not candidates for tissue Plasminogen Activator (t-PA) or Mechanical Thrombectomy (MT) pre- and post-COVID pandemic.

Aspirin

Identify mentioned drugs from the abstract title

A phase 1b study of nivolumab in patients with autoimmune disorders and advanced malignancies (AIM-NIVO)

NIVO;;Nivolumab

Identify mentioned drugs from the abstract title

Desmopressin is twice effective in females: A systematic review and meta-analysis on medical treatment of nocturia

Desmopressin

Identify mentioned drugs from the abstract title

Clinical and microbiological outcomes for Enterobacterales uropathogens in the Phase 3 ADAPT-PO Study of oral tebipenem pivoxil hydrobromide

Tebipenem Pivoxil Hydrobromide

Identify mentioned drugs from the abstract title

A randomized, pre-surgical study to investigate the biological effects of AZD9833 doses in women with ER-positive HER2-negative primary breast cancer (SERENA-3)

AZD-9833

Identify mentioned drugs from the abstract title

Bms-986158, A Potent Bet Inhibitor, As Monotherapy And In Combination With Ruxolitinib Or Fedratinib In Intermediate- Or High-Risk Myelofibrosis (Mf): Results From A Phase 1/2 Study

BMS-986158;;Fedratinib;;Ruxolitinib

Identify mentioned drugs from the abstract title

ASTX660, a non-peptidomimetic antagonist of cIAP1/2 and XIAP, enhances immune mediated tumor killing and induction of immunogenic cell death

ASTX-660

Identify mentioned drugs from the abstract title

ARTISTRY-1: Nemvaleukin alfa monotherapy and in combination with pembrolizumab in patients (pts) with advanced solid tumors.

Nemvaleukin Alfa;;Pembrolizumab

Identify mentioned drugs from the abstract title

BATF3/MYC axis drives hyper-proliferation of TET2 deficient CAR T cells

CAR T-cell

Identify mentioned drugs from the abstract title

Activity of OSE-2101 in HLA-A2+ non-small cell lung cancer (NSCLC) patients after failure to immune checkpoint inhibitors (IO): Final results of Phase 3 Atalante-1 randomised trial

OSE-2101

Identify mentioned drugs from the abstract title

A Phase I Study of CD19 Chimeric Antigen Receptor-T Cells Generated By the PiggyBac Transposon Vector for Acute Lymphoblastic Leukemia

CD19 CAR T-Cell

Identify mentioned drugs from the abstract title

An Open-Label, Multicenter, Phase 1/2 Clinical Trial of RP1 as a Single Agent and in Combination with Nivolumab in Patients with Solid Tumors [IGNYTE]

RP1;;Nivolumab

Identify mentioned drugs from the abstract title

Adverse events and estimated costs with the combination of ipilimumab and nivolumab in metastatic melanoma patients.

Ipilimumab;;Nivolumab

Identify mentioned drugs from the abstract title

A Phase 1B/2 Study Of Tp-0903 And Decitabine Targeting Mutant Tp53 And/Or Complex Karyotype In Patients With Untreated Acute Myeloid Leukemia (Aml) >= Age 60 Years: Final Results

Decitabine;;TP-0903

Identify mentioned drugs from the abstract title

D3L-001, a novel bispecific antibody targeting HER2 and CD47, demonstrates potent preclinical efficacy in solid tumors.

D3L-001

Identify mentioned drugs from the abstract title

Chemotherapy and bevacizumab prescription in routine management of metastatic colorectal cancer in Uruguay: Is clinical practice following the evidence?

Bevacizumab

Identify mentioned drugs from the abstract title

Allo-Hct In Myelofibrosis - Current And Future Trends

ALLO

Identify mentioned drugs from the abstract title

A functional approach to identifying and engineering TCRs results in highly-potent and specific TCRs for TCR-T cell therapy

TCR-T Cell

Identify mentioned drugs from the abstract title

The Role Of Treatment Strategy In Reducing The Disability Risk In Multiple Sclerosis

null

Identify mentioned drugs from the abstract title

68Ga-PSMA PET radiomics for the prediction of post-surgical ISUP grade in primary prostate cancer patients

68Ga-PSMA

Identify mentioned drugs from the abstract title

CRISPR/Cas9 gene-edited, allogeneic anti-CD83 CAR-T cells demonstrate potent activity in GvHD and AML tumor models

Anti-CD83 CAR-T Cell

Identify mentioned drugs from the abstract title

Anlotinib plus chemotherapy as first-line therapy for gastrointestinal tumor patients with unresectable liver metastasis: A multicenter, multicohort clinical trial (ALTER-G-001).

Anlotinib