|
{ |
|
"form": [ |
|
{ |
|
"box": [ |
|
84, |
|
109, |
|
136, |
|
119 |
|
], |
|
"text": "COMPOUND", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
84, |
|
109, |
|
136, |
|
119 |
|
], |
|
"text": "COMPOUND" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
0, |
|
37 |
|
] |
|
], |
|
"id": 0 |
|
}, |
|
{ |
|
"box": [ |
|
85, |
|
141, |
|
119, |
|
152 |
|
], |
|
"text": "SOURCE", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
85, |
|
141, |
|
119, |
|
152 |
|
], |
|
"text": "SOURCE" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
1, |
|
38 |
|
] |
|
], |
|
"id": 1 |
|
}, |
|
{ |
|
"box": [ |
|
84, |
|
203, |
|
155, |
|
214 |
|
], |
|
"text": "INVESTIGATOR(S)", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
84, |
|
203, |
|
155, |
|
214 |
|
], |
|
"text": "INVESTIGATOR(S)" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
2, |
|
44 |
|
] |
|
], |
|
"id": 2 |
|
}, |
|
{ |
|
"box": [ |
|
84, |
|
232, |
|
141, |
|
243 |
|
], |
|
"text": "SIGNATURE(S)", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
84, |
|
232, |
|
141, |
|
243 |
|
], |
|
"text": "SIGNATURE(S)" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
3, |
|
45 |
|
] |
|
], |
|
"id": 3 |
|
}, |
|
{ |
|
"box": [ |
|
508, |
|
170, |
|
551, |
|
183 |
|
], |
|
"text": "REPORTED", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
508, |
|
170, |
|
551, |
|
183 |
|
], |
|
"text": "REPORTED" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
4, |
|
43 |
|
] |
|
], |
|
"id": 4 |
|
}, |
|
{ |
|
"box": [ |
|
327, |
|
170, |
|
361, |
|
183 |
|
], |
|
"text": "TESTED", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
327, |
|
170, |
|
361, |
|
183 |
|
], |
|
"text": "TESTED" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
5, |
|
12 |
|
] |
|
], |
|
"id": 5 |
|
}, |
|
{ |
|
"box": [ |
|
334, |
|
296, |
|
361, |
|
310 |
|
], |
|
"text": "MALE", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
334, |
|
296, |
|
361, |
|
310 |
|
], |
|
"text": "MALE" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
6, |
|
13 |
|
] |
|
], |
|
"id": 6 |
|
}, |
|
{ |
|
"box": [ |
|
404, |
|
296, |
|
438, |
|
309 |
|
], |
|
"text": "FEMALE", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
404, |
|
296, |
|
438, |
|
309 |
|
], |
|
"text": "FEMALE" |
|
} |
|
], |
|
"linking": [], |
|
"id": 7 |
|
}, |
|
{ |
|
"box": [ |
|
404, |
|
328, |
|
440, |
|
339 |
|
], |
|
"text": "SOURCE", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
404, |
|
328, |
|
440, |
|
339 |
|
], |
|
"text": "SOURCE" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
8, |
|
15 |
|
], |
|
[ |
|
8, |
|
16 |
|
] |
|
], |
|
"id": 8 |
|
}, |
|
{ |
|
"box": [ |
|
180, |
|
162, |
|
219, |
|
182 |
|
], |
|
"text": "Unk.", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
180, |
|
162, |
|
219, |
|
182 |
|
], |
|
"text": "Unk." |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
42, |
|
9 |
|
] |
|
], |
|
"id": 9 |
|
}, |
|
{ |
|
"box": [ |
|
300, |
|
360, |
|
317, |
|
373 |
|
], |
|
"text": "P.O.", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
300, |
|
360, |
|
317, |
|
373 |
|
], |
|
"text": "P.O." |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
52, |
|
10 |
|
], |
|
[ |
|
10, |
|
17 |
|
] |
|
], |
|
"id": 10 |
|
}, |
|
{ |
|
"box": [ |
|
669, |
|
127, |
|
697, |
|
151 |
|
], |
|
"text": "A4", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
669, |
|
127, |
|
697, |
|
151 |
|
], |
|
"text": "A4" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
41, |
|
11 |
|
] |
|
], |
|
"id": 11 |
|
}, |
|
{ |
|
"box": [ |
|
377, |
|
163, |
|
451, |
|
180 |
|
], |
|
"text": "12/28/78", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
377, |
|
163, |
|
451, |
|
180 |
|
], |
|
"text": "12/28/78" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
5, |
|
12 |
|
] |
|
], |
|
"id": 12 |
|
}, |
|
{ |
|
"box": [ |
|
369, |
|
284, |
|
387, |
|
302 |
|
], |
|
"text": "X", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
369, |
|
284, |
|
387, |
|
302 |
|
], |
|
"text": "X" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
6, |
|
13 |
|
] |
|
], |
|
"id": 13 |
|
}, |
|
{ |
|
"box": [ |
|
591, |
|
286, |
|
630, |
|
303 |
|
], |
|
"text": "Unk.", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
591, |
|
286, |
|
630, |
|
303 |
|
], |
|
"text": "Unk." |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
50, |
|
14 |
|
] |
|
], |
|
"id": 14 |
|
}, |
|
{ |
|
"box": [ |
|
473, |
|
323, |
|
514, |
|
338 |
|
], |
|
"text": "Camm", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
473, |
|
323, |
|
514, |
|
338 |
|
], |
|
"text": "Camm" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
8, |
|
15 |
|
] |
|
], |
|
"id": 15 |
|
}, |
|
{ |
|
"box": [ |
|
522, |
|
320, |
|
596, |
|
335 |
|
], |
|
"text": "Research", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
522, |
|
320, |
|
596, |
|
335 |
|
], |
|
"text": "Research" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
8, |
|
16 |
|
] |
|
], |
|
"id": 16 |
|
}, |
|
{ |
|
"box": [ |
|
288, |
|
360, |
|
302, |
|
373 |
|
], |
|
"text": "☑", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
288, |
|
360, |
|
302, |
|
373 |
|
], |
|
"text": "☑" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
10, |
|
17 |
|
] |
|
], |
|
"id": 17 |
|
}, |
|
{ |
|
"box": [ |
|
201, |
|
388, |
|
218, |
|
406 |
|
], |
|
"text": "☑", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
201, |
|
388, |
|
218, |
|
406 |
|
], |
|
"text": "☑" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
57, |
|
18 |
|
] |
|
], |
|
"id": 18 |
|
}, |
|
{ |
|
"box": [ |
|
216, |
|
487, |
|
231, |
|
504 |
|
], |
|
"text": "5", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
216, |
|
487, |
|
231, |
|
504 |
|
], |
|
"text": "5" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
19 |
|
] |
|
], |
|
"id": 19 |
|
}, |
|
{ |
|
"box": [ |
|
208, |
|
517, |
|
228, |
|
532 |
|
], |
|
"text": "10", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
208, |
|
517, |
|
228, |
|
532 |
|
], |
|
"text": "10" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
20 |
|
] |
|
], |
|
"id": 20 |
|
}, |
|
{ |
|
"box": [ |
|
209, |
|
546, |
|
230, |
|
561 |
|
], |
|
"text": "10", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
209, |
|
546, |
|
230, |
|
561 |
|
], |
|
"text": "10" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
21 |
|
] |
|
], |
|
"id": 21 |
|
}, |
|
{ |
|
"box": [ |
|
211, |
|
578, |
|
231, |
|
593 |
|
], |
|
"text": "10", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
211, |
|
578, |
|
231, |
|
593 |
|
], |
|
"text": "10" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
22 |
|
] |
|
], |
|
"id": 22 |
|
}, |
|
{ |
|
"box": [ |
|
208, |
|
606, |
|
230, |
|
620 |
|
], |
|
"text": "10", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
208, |
|
606, |
|
230, |
|
620 |
|
], |
|
"text": "10" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
23 |
|
] |
|
], |
|
"id": 23 |
|
}, |
|
{ |
|
"box": [ |
|
122, |
|
483, |
|
132, |
|
496 |
|
], |
|
"text": "1", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
122, |
|
483, |
|
132, |
|
496 |
|
], |
|
"text": "1" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
24 |
|
] |
|
], |
|
"id": 24 |
|
}, |
|
{ |
|
"box": [ |
|
122, |
|
511, |
|
133, |
|
526 |
|
], |
|
"text": "2", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
122, |
|
511, |
|
133, |
|
526 |
|
], |
|
"text": "2" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
25 |
|
] |
|
], |
|
"id": 25 |
|
}, |
|
{ |
|
"box": [ |
|
123, |
|
541, |
|
133, |
|
555 |
|
], |
|
"text": "3", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
123, |
|
541, |
|
133, |
|
555 |
|
], |
|
"text": "3" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
26 |
|
] |
|
], |
|
"id": 26 |
|
}, |
|
{ |
|
"box": [ |
|
122, |
|
571, |
|
133, |
|
585 |
|
], |
|
"text": "4", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
122, |
|
571, |
|
133, |
|
585 |
|
], |
|
"text": "4" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
27 |
|
] |
|
], |
|
"id": 27 |
|
}, |
|
{ |
|
"box": [ |
|
123, |
|
602, |
|
133, |
|
615 |
|
], |
|
"text": "5", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
123, |
|
602, |
|
133, |
|
615 |
|
], |
|
"text": "5" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
28 |
|
] |
|
], |
|
"id": 28 |
|
}, |
|
{ |
|
"box": [ |
|
383, |
|
487, |
|
424, |
|
504 |
|
], |
|
"text": "1800", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
383, |
|
487, |
|
424, |
|
504 |
|
], |
|
"text": "1800" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
29 |
|
] |
|
], |
|
"id": 29 |
|
}, |
|
{ |
|
"box": [ |
|
380, |
|
518, |
|
421, |
|
532 |
|
], |
|
"text": "2160", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
380, |
|
518, |
|
421, |
|
532 |
|
], |
|
"text": "2160" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
30 |
|
] |
|
], |
|
"id": 30 |
|
}, |
|
{ |
|
"box": [ |
|
383, |
|
547, |
|
419, |
|
562 |
|
], |
|
"text": "2592", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
383, |
|
547, |
|
419, |
|
562 |
|
], |
|
"text": "2592" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
31 |
|
] |
|
], |
|
"id": 31 |
|
}, |
|
{ |
|
"box": [ |
|
384, |
|
577, |
|
420, |
|
594 |
|
], |
|
"text": "3732", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
384, |
|
577, |
|
420, |
|
594 |
|
], |
|
"text": "3732" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
32 |
|
] |
|
], |
|
"id": 32 |
|
}, |
|
{ |
|
"box": [ |
|
381, |
|
605, |
|
420, |
|
620 |
|
], |
|
"text": "4479", |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"box": [ |
|
381, |
|
605, |
|
420, |
|
620 |
|
], |
|
"text": "4479" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
33 |
|
] |
|
], |
|
"id": 33 |
|
}, |
|
{ |
|
"box": [ |
|
82, |
|
740, |
|
135, |
|
753 |
|
], |
|
"text": "CONCLUSION", |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"box": [ |
|
82, |
|
740, |
|
135, |
|
753 |
|
], |
|
"text": "CONCLUSION" |
|
} |
|
], |
|
"linking": [ |
|
[ |
|
34, |
|
79 |
|
], |
|
[ |
|
34, |
|
78 |
|
] |
|
], |
|
"id": 34 |
|
}, |
|
{ |
|
"box": [ |
|
680, |
|
824, |
|
701, |
|
920 |
|
], |
|
"text": "00040534", |
|
"label": "other", |
|
"words": [ |
|
{ |
|
"box": [ |
|
680, |
|
824, |
|
701, |
|
920 |
|
], |
|
"text": "00040534" |
|
} |
|
], |
|
"linking": [], |
|
"id": 35 |
|
}, |
|
{ |
|
"text": "ACUTE TOXICITY IN MICE", |
|
"box": [ |
|
295, |
|
56, |
|
512, |
|
79 |
|
], |
|
"linking": [], |
|
"label": "header", |
|
"words": [ |
|
{ |
|
"text": "ACUTE", |
|
"box": [ |
|
295, |
|
56, |
|
354, |
|
76 |
|
] |
|
}, |
|
{ |
|
"text": "TOXICITY", |
|
"box": [ |
|
358, |
|
57, |
|
438, |
|
77 |
|
] |
|
}, |
|
{ |
|
"text": "IN", |
|
"box": [ |
|
441, |
|
59, |
|
461, |
|
79 |
|
] |
|
}, |
|
{ |
|
"text": "MICE", |
|
"box": [ |
|
466, |
|
57, |
|
512, |
|
75 |
|
] |
|
} |
|
], |
|
"id": 36 |
|
}, |
|
{ |
|
"text": "3-Hydroxy-3-methylbutanoic acid (Tur 13)", |
|
"box": [ |
|
145, |
|
98, |
|
507, |
|
116 |
|
], |
|
"linking": [ |
|
[ |
|
0, |
|
37 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "3-Hydroxy-3-methylbutanoic", |
|
"box": [ |
|
145, |
|
98, |
|
384, |
|
116 |
|
] |
|
}, |
|
{ |
|
"text": "acid", |
|
"box": [ |
|
392, |
|
99, |
|
427, |
|
114 |
|
] |
|
}, |
|
{ |
|
"text": "(Tur", |
|
"box": [ |
|
439, |
|
99, |
|
474, |
|
116 |
|
] |
|
}, |
|
{ |
|
"text": "13)", |
|
"box": [ |
|
483, |
|
99, |
|
507, |
|
116 |
|
] |
|
} |
|
], |
|
"id": 37 |
|
}, |
|
{ |
|
"text": "Lorillard - Organic Chemistry", |
|
"box": [ |
|
144, |
|
128, |
|
409, |
|
152 |
|
], |
|
"linking": [ |
|
[ |
|
1, |
|
38 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Lorillard", |
|
"box": [ |
|
144, |
|
131, |
|
228, |
|
149 |
|
] |
|
}, |
|
{ |
|
"text": "-", |
|
"box": [ |
|
236, |
|
135, |
|
247, |
|
143 |
|
] |
|
}, |
|
{ |
|
"text": "Organic", |
|
"box": [ |
|
254, |
|
130, |
|
317, |
|
148 |
|
] |
|
}, |
|
{ |
|
"text": "Chemistry", |
|
"box": [ |
|
327, |
|
128, |
|
409, |
|
152 |
|
] |
|
} |
|
], |
|
"id": 38 |
|
}, |
|
{ |
|
"text": "LORILLARD NO", |
|
"box": [ |
|
411, |
|
141, |
|
473, |
|
152 |
|
], |
|
"linking": [ |
|
[ |
|
39, |
|
40 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "LORILLARD", |
|
"box": [ |
|
411, |
|
141, |
|
457, |
|
152 |
|
] |
|
}, |
|
{ |
|
"text": "NO", |
|
"box": [ |
|
459, |
|
142, |
|
473, |
|
152 |
|
] |
|
} |
|
], |
|
"id": 39 |
|
}, |
|
{ |
|
"text": "OR39- 23", |
|
"box": [ |
|
499, |
|
127, |
|
564, |
|
144 |
|
], |
|
"linking": [ |
|
[ |
|
39, |
|
40 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "OR39-", |
|
"box": [ |
|
499, |
|
127, |
|
549, |
|
142 |
|
] |
|
}, |
|
{ |
|
"text": "23", |
|
"box": [ |
|
549, |
|
127, |
|
564, |
|
144 |
|
] |
|
} |
|
], |
|
"id": 40 |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
615, |
|
141, |
|
650, |
|
153 |
|
], |
|
"linking": [ |
|
[ |
|
41, |
|
11 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "", |
|
"box": [ |
|
615, |
|
141, |
|
636, |
|
152 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
637, |
|
142, |
|
650, |
|
153 |
|
] |
|
} |
|
], |
|
"id": 41 |
|
}, |
|
{ |
|
"text": "DATE RECEIVED", |
|
"box": [ |
|
85, |
|
172, |
|
149, |
|
183 |
|
], |
|
"linking": [ |
|
[ |
|
42, |
|
9 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "DATE", |
|
"box": [ |
|
85, |
|
172, |
|
107, |
|
183 |
|
] |
|
}, |
|
{ |
|
"text": "RECEIVED", |
|
"box": [ |
|
108, |
|
172, |
|
149, |
|
182 |
|
] |
|
} |
|
], |
|
"id": 42 |
|
}, |
|
{ |
|
"text": "5/3/79 10/6/80 , Update", |
|
"box": [ |
|
573, |
|
148, |
|
713, |
|
184 |
|
], |
|
"linking": [ |
|
[ |
|
4, |
|
43 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "5/3/79", |
|
"box": [ |
|
573, |
|
148, |
|
632, |
|
165 |
|
] |
|
}, |
|
{ |
|
"text": "10/6/80", |
|
"box": [ |
|
574, |
|
163, |
|
640, |
|
178 |
|
] |
|
}, |
|
{ |
|
"text": ",", |
|
"box": [ |
|
641, |
|
173, |
|
648, |
|
184 |
|
] |
|
}, |
|
{ |
|
"text": "Update", |
|
"box": [ |
|
656, |
|
166, |
|
713, |
|
183 |
|
] |
|
} |
|
], |
|
"id": 43 |
|
}, |
|
{ |
|
"text": "H. S. Tong & M. S. Forte'", |
|
"box": [ |
|
198, |
|
194, |
|
427, |
|
213 |
|
], |
|
"linking": [ |
|
[ |
|
2, |
|
44 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "H.", |
|
"box": [ |
|
198, |
|
196, |
|
220, |
|
211 |
|
] |
|
}, |
|
{ |
|
"text": "S.", |
|
"box": [ |
|
226, |
|
198, |
|
246, |
|
211 |
|
] |
|
}, |
|
{ |
|
"text": "Tong", |
|
"box": [ |
|
256, |
|
198, |
|
295, |
|
212 |
|
] |
|
}, |
|
{ |
|
"text": "&", |
|
"box": [ |
|
300, |
|
197, |
|
311, |
|
211 |
|
] |
|
}, |
|
{ |
|
"text": "M.", |
|
"box": [ |
|
320, |
|
196, |
|
337, |
|
213 |
|
] |
|
}, |
|
{ |
|
"text": "S.", |
|
"box": [ |
|
345, |
|
194, |
|
362, |
|
211 |
|
] |
|
}, |
|
{ |
|
"text": "Forte'", |
|
"box": [ |
|
373, |
|
197, |
|
427, |
|
210 |
|
] |
|
} |
|
], |
|
"id": 44 |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
186, |
|
211, |
|
730, |
|
264 |
|
], |
|
"linking": [ |
|
[ |
|
3, |
|
45 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "", |
|
"box": [ |
|
186, |
|
215, |
|
221, |
|
240 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
215, |
|
216, |
|
253, |
|
245 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
254, |
|
215, |
|
332, |
|
264 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
423, |
|
222, |
|
464, |
|
243 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
466, |
|
214, |
|
487, |
|
243 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
493, |
|
211, |
|
564, |
|
239 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
567, |
|
216, |
|
616, |
|
252 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
620, |
|
216, |
|
642, |
|
241 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
649, |
|
211, |
|
730, |
|
240 |
|
] |
|
} |
|
], |
|
"id": 45 |
|
}, |
|
{ |
|
"text": "B1014- 23", |
|
"box": [ |
|
637, |
|
194, |
|
714, |
|
209 |
|
], |
|
"linking": [ |
|
[ |
|
47, |
|
46 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "B1014-", |
|
"box": [ |
|
637, |
|
194, |
|
694, |
|
209 |
|
] |
|
}, |
|
{ |
|
"text": "23", |
|
"box": [ |
|
693, |
|
194, |
|
714, |
|
209 |
|
] |
|
} |
|
], |
|
"id": 46 |
|
}, |
|
{ |
|
"text": "NOTEBOOK PAGE", |
|
"box": [ |
|
543, |
|
203, |
|
617, |
|
215 |
|
], |
|
"linking": [ |
|
[ |
|
47, |
|
46 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "NOTEBOOK", |
|
"box": [ |
|
543, |
|
203, |
|
593, |
|
214 |
|
] |
|
}, |
|
{ |
|
"text": "PAGE", |
|
"box": [ |
|
592, |
|
205, |
|
617, |
|
215 |
|
] |
|
} |
|
], |
|
"id": 47 |
|
}, |
|
{ |
|
"text": "STRAIN OF MICE", |
|
"box": [ |
|
82, |
|
297, |
|
149, |
|
310 |
|
], |
|
"linking": [ |
|
[ |
|
48, |
|
49 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "STRAIN", |
|
"box": [ |
|
82, |
|
297, |
|
111, |
|
308 |
|
] |
|
}, |
|
{ |
|
"text": "OF", |
|
"box": [ |
|
113, |
|
297, |
|
127, |
|
310 |
|
] |
|
}, |
|
{ |
|
"text": "MICE", |
|
"box": [ |
|
128, |
|
297, |
|
149, |
|
310 |
|
] |
|
} |
|
], |
|
"id": 48 |
|
}, |
|
{ |
|
"text": "Swiss- Webster", |
|
"box": [ |
|
162, |
|
286, |
|
282, |
|
306 |
|
], |
|
"linking": [ |
|
[ |
|
48, |
|
49 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Swiss-", |
|
"box": [ |
|
162, |
|
286, |
|
221, |
|
306 |
|
] |
|
}, |
|
{ |
|
"text": "Webster", |
|
"box": [ |
|
219, |
|
288, |
|
282, |
|
303 |
|
] |
|
} |
|
], |
|
"id": 49 |
|
}, |
|
{ |
|
"text": "DATE RECEIVED", |
|
"box": [ |
|
493, |
|
297, |
|
560, |
|
310 |
|
], |
|
"linking": [ |
|
[ |
|
50, |
|
14 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "DATE", |
|
"box": [ |
|
493, |
|
297, |
|
518, |
|
310 |
|
] |
|
}, |
|
{ |
|
"text": "RECEIVED", |
|
"box": [ |
|
517, |
|
297, |
|
560, |
|
310 |
|
] |
|
} |
|
], |
|
"id": 50 |
|
}, |
|
{ |
|
"text": "AVERAGE WEIGHT RANGE (GM)", |
|
"box": [ |
|
84, |
|
327, |
|
208, |
|
339 |
|
], |
|
"linking": [], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "AVERAGE", |
|
"box": [ |
|
84, |
|
327, |
|
123, |
|
338 |
|
] |
|
}, |
|
{ |
|
"text": "WEIGHT", |
|
"box": [ |
|
124, |
|
328, |
|
156, |
|
339 |
|
] |
|
}, |
|
{ |
|
"text": "RANGE", |
|
"box": [ |
|
158, |
|
328, |
|
186, |
|
338 |
|
] |
|
}, |
|
{ |
|
"text": "(GM)", |
|
"box": [ |
|
186, |
|
328, |
|
208, |
|
339 |
|
] |
|
} |
|
], |
|
"id": 51 |
|
}, |
|
{ |
|
"text": "ROUTE OF COMPOUND ADMINISTRATION", |
|
"box": [ |
|
84, |
|
362, |
|
246, |
|
373 |
|
], |
|
"linking": [ |
|
[ |
|
52, |
|
10 |
|
], |
|
[ |
|
52, |
|
53 |
|
], |
|
[ |
|
52, |
|
54 |
|
], |
|
[ |
|
52, |
|
55 |
|
] |
|
], |
|
"label": "header", |
|
"words": [ |
|
{ |
|
"text": "ROUTE", |
|
"box": [ |
|
84, |
|
362, |
|
112, |
|
372 |
|
] |
|
}, |
|
{ |
|
"text": "OF", |
|
"box": [ |
|
112, |
|
362, |
|
126, |
|
372 |
|
] |
|
}, |
|
{ |
|
"text": "COMPOUND", |
|
"box": [ |
|
124, |
|
362, |
|
173, |
|
373 |
|
] |
|
}, |
|
{ |
|
"text": "ADMINISTRATION", |
|
"box": [ |
|
176, |
|
362, |
|
246, |
|
373 |
|
] |
|
} |
|
], |
|
"id": 52 |
|
}, |
|
{ |
|
"text": "☐ I.P.", |
|
"box": [ |
|
362, |
|
362, |
|
386, |
|
373 |
|
], |
|
"linking": [ |
|
[ |
|
52, |
|
53 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
362, |
|
362, |
|
372, |
|
373 |
|
] |
|
}, |
|
{ |
|
"text": "I.P.", |
|
"box": [ |
|
373, |
|
365, |
|
386, |
|
373 |
|
] |
|
} |
|
], |
|
"id": 53 |
|
}, |
|
{ |
|
"text": "☐ I.V.", |
|
"box": [ |
|
429, |
|
362, |
|
455, |
|
373 |
|
], |
|
"linking": [ |
|
[ |
|
52, |
|
54 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
429, |
|
362, |
|
440, |
|
373 |
|
] |
|
}, |
|
{ |
|
"text": "I.V.", |
|
"box": [ |
|
444, |
|
362, |
|
455, |
|
373 |
|
] |
|
} |
|
], |
|
"id": 54 |
|
}, |
|
{ |
|
"text": "☐ INHALATION", |
|
"box": [ |
|
499, |
|
363, |
|
562, |
|
375 |
|
], |
|
"linking": [ |
|
[ |
|
52, |
|
55 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
499, |
|
365, |
|
510, |
|
375 |
|
] |
|
}, |
|
{ |
|
"text": "INHALATION", |
|
"box": [ |
|
510, |
|
363, |
|
562, |
|
374 |
|
] |
|
} |
|
], |
|
"id": 55 |
|
}, |
|
{ |
|
"text": "COMPOUND ", |
|
"box": [ |
|
82, |
|
390, |
|
169, |
|
403 |
|
], |
|
"linking": [ |
|
[ |
|
56, |
|
57 |
|
], |
|
[ |
|
56, |
|
58 |
|
], |
|
[ |
|
56, |
|
59 |
|
], |
|
[ |
|
56, |
|
60 |
|
] |
|
], |
|
"label": "header", |
|
"words": [ |
|
{ |
|
"text": "COMPOUND", |
|
"box": [ |
|
82, |
|
390, |
|
132, |
|
403 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
133, |
|
391, |
|
169, |
|
401 |
|
] |
|
} |
|
], |
|
"id": 56 |
|
}, |
|
{ |
|
"text": ".5 % METHYL CELULOSE", |
|
"box": [ |
|
221, |
|
390, |
|
328, |
|
405 |
|
], |
|
"linking": [ |
|
[ |
|
56, |
|
57 |
|
], |
|
[ |
|
57, |
|
18 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": ".5", |
|
"box": [ |
|
221, |
|
390, |
|
239, |
|
405 |
|
] |
|
}, |
|
{ |
|
"text": "%", |
|
"box": [ |
|
239, |
|
391, |
|
250, |
|
399 |
|
] |
|
}, |
|
{ |
|
"text": "METHYL", |
|
"box": [ |
|
249, |
|
390, |
|
278, |
|
400 |
|
] |
|
}, |
|
{ |
|
"text": "CELULOSE", |
|
"box": [ |
|
281, |
|
390, |
|
328, |
|
401 |
|
] |
|
} |
|
], |
|
"id": 57 |
|
}, |
|
{ |
|
"text": "☐ CORN OIL", |
|
"box": [ |
|
369, |
|
390, |
|
423, |
|
403 |
|
], |
|
"linking": [ |
|
[ |
|
56, |
|
58 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
369, |
|
390, |
|
383, |
|
403 |
|
] |
|
}, |
|
{ |
|
"text": "CORN", |
|
"box": [ |
|
381, |
|
390, |
|
406, |
|
400 |
|
] |
|
}, |
|
{ |
|
"text": "OIL", |
|
"box": [ |
|
408, |
|
392, |
|
423, |
|
403 |
|
] |
|
} |
|
], |
|
"id": 58 |
|
}, |
|
{ |
|
"text": "☐ SALINE", |
|
"box": [ |
|
466, |
|
390, |
|
506, |
|
401 |
|
], |
|
"linking": [ |
|
[ |
|
56, |
|
59 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
466, |
|
390, |
|
479, |
|
401 |
|
] |
|
}, |
|
{ |
|
"text": "SALINE", |
|
"box": [ |
|
479, |
|
392, |
|
506, |
|
400 |
|
] |
|
} |
|
], |
|
"id": 59 |
|
}, |
|
{ |
|
"text": "☐ OTHER", |
|
"box": [ |
|
550, |
|
391, |
|
589, |
|
404 |
|
], |
|
"linking": [ |
|
[ |
|
56, |
|
60 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "☐", |
|
"box": [ |
|
550, |
|
391, |
|
563, |
|
404 |
|
] |
|
}, |
|
{ |
|
"text": "OTHER", |
|
"box": [ |
|
561, |
|
391, |
|
589, |
|
401 |
|
] |
|
} |
|
], |
|
"id": 60 |
|
}, |
|
{ |
|
"text": "GROUP NO.", |
|
"box": [ |
|
105, |
|
447, |
|
153, |
|
458 |
|
], |
|
"linking": [ |
|
[ |
|
61, |
|
24 |
|
], |
|
[ |
|
61, |
|
25 |
|
], |
|
[ |
|
61, |
|
26 |
|
], |
|
[ |
|
61, |
|
27 |
|
], |
|
[ |
|
61, |
|
28 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "GROUP", |
|
"box": [ |
|
105, |
|
447, |
|
136, |
|
458 |
|
] |
|
}, |
|
{ |
|
"text": "NO.", |
|
"box": [ |
|
138, |
|
448, |
|
153, |
|
458 |
|
] |
|
} |
|
], |
|
"id": 61 |
|
}, |
|
{ |
|
"text": "% SOLUTION", |
|
"box": [ |
|
218, |
|
448, |
|
269, |
|
459 |
|
], |
|
"linking": [ |
|
[ |
|
62, |
|
19 |
|
], |
|
[ |
|
62, |
|
20 |
|
], |
|
[ |
|
62, |
|
21 |
|
], |
|
[ |
|
62, |
|
22 |
|
], |
|
[ |
|
62, |
|
23 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "%", |
|
"box": [ |
|
218, |
|
448, |
|
228, |
|
458 |
|
] |
|
}, |
|
{ |
|
"text": "SOLUTION", |
|
"box": [ |
|
228, |
|
448, |
|
269, |
|
459 |
|
] |
|
} |
|
], |
|
"id": 62 |
|
}, |
|
{ |
|
"text": "DOSAGE (mg/ kg BODY WEIGHT)", |
|
"box": [ |
|
370, |
|
448, |
|
455, |
|
470 |
|
], |
|
"linking": [ |
|
[ |
|
63, |
|
29 |
|
], |
|
[ |
|
63, |
|
30 |
|
], |
|
[ |
|
63, |
|
31 |
|
], |
|
[ |
|
63, |
|
32 |
|
], |
|
[ |
|
63, |
|
33 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "DOSAGE", |
|
"box": [ |
|
394, |
|
448, |
|
433, |
|
456 |
|
] |
|
}, |
|
{ |
|
"text": "(mg/", |
|
"box": [ |
|
370, |
|
455, |
|
387, |
|
468 |
|
] |
|
}, |
|
{ |
|
"text": "kg", |
|
"box": [ |
|
387, |
|
457, |
|
398, |
|
470 |
|
] |
|
}, |
|
{ |
|
"text": "BODY", |
|
"box": [ |
|
398, |
|
457, |
|
419, |
|
467 |
|
] |
|
}, |
|
{ |
|
"text": "WEIGHT)", |
|
"box": [ |
|
423, |
|
455, |
|
455, |
|
468 |
|
] |
|
} |
|
], |
|
"id": 63 |
|
}, |
|
{ |
|
"text": "RESULTS (NO TESTED)", |
|
"box": [ |
|
588, |
|
450, |
|
679, |
|
468 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
65 |
|
], |
|
[ |
|
64, |
|
66 |
|
], |
|
[ |
|
64, |
|
67 |
|
], |
|
[ |
|
64, |
|
68 |
|
], |
|
[ |
|
64, |
|
69 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "RESULTS", |
|
"box": [ |
|
613, |
|
450, |
|
649, |
|
460 |
|
] |
|
}, |
|
{ |
|
"text": "(NO", |
|
"box": [ |
|
588, |
|
455, |
|
605, |
|
468 |
|
] |
|
}, |
|
{ |
|
"text": "", |
|
"box": [ |
|
606, |
|
458, |
|
644, |
|
468 |
|
] |
|
}, |
|
{ |
|
"text": "TESTED)", |
|
"box": [ |
|
645, |
|
457, |
|
679, |
|
468 |
|
] |
|
} |
|
], |
|
"id": 64 |
|
}, |
|
{ |
|
"text": "1/ 6", |
|
"box": [ |
|
574, |
|
489, |
|
603, |
|
506 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
65 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "1/", |
|
"box": [ |
|
574, |
|
489, |
|
592, |
|
506 |
|
] |
|
}, |
|
{ |
|
"text": "6", |
|
"box": [ |
|
592, |
|
490, |
|
603, |
|
501 |
|
] |
|
} |
|
], |
|
"id": 65 |
|
}, |
|
{ |
|
"text": "0/ 6", |
|
"box": [ |
|
575, |
|
515, |
|
607, |
|
532 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
66 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "0/", |
|
"box": [ |
|
575, |
|
515, |
|
593, |
|
532 |
|
] |
|
}, |
|
{ |
|
"text": "6", |
|
"box": [ |
|
594, |
|
518, |
|
607, |
|
529 |
|
] |
|
} |
|
], |
|
"id": 66 |
|
}, |
|
{ |
|
"text": "0/ 6", |
|
"box": [ |
|
575, |
|
545, |
|
603, |
|
563 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
67 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "0/", |
|
"box": [ |
|
575, |
|
545, |
|
592, |
|
563 |
|
] |
|
}, |
|
{ |
|
"text": "6", |
|
"box": [ |
|
592, |
|
546, |
|
603, |
|
561 |
|
] |
|
} |
|
], |
|
"id": 67 |
|
}, |
|
{ |
|
"text": "3/ 6", |
|
"box": [ |
|
575, |
|
575, |
|
605, |
|
594 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
68 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "3/", |
|
"box": [ |
|
575, |
|
575, |
|
593, |
|
590 |
|
] |
|
}, |
|
{ |
|
"text": "6", |
|
"box": [ |
|
594, |
|
577, |
|
605, |
|
594 |
|
] |
|
} |
|
], |
|
"id": 68 |
|
}, |
|
{ |
|
"text": "6/ 6", |
|
"box": [ |
|
575, |
|
605, |
|
604, |
|
623 |
|
], |
|
"linking": [ |
|
[ |
|
64, |
|
69 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "6/", |
|
"box": [ |
|
575, |
|
606, |
|
593, |
|
623 |
|
] |
|
}, |
|
{ |
|
"text": "6", |
|
"box": [ |
|
596, |
|
605, |
|
604, |
|
622 |
|
] |
|
} |
|
], |
|
"id": 69 |
|
}, |
|
{ |
|
"text": "REFERENCE FOR CALCULATION", |
|
"box": [ |
|
82, |
|
651, |
|
203, |
|
662 |
|
], |
|
"linking": [ |
|
[ |
|
70, |
|
71 |
|
], |
|
[ |
|
70, |
|
72 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "REFERENCE", |
|
"box": [ |
|
82, |
|
651, |
|
128, |
|
662 |
|
] |
|
}, |
|
{ |
|
"text": "FOR", |
|
"box": [ |
|
128, |
|
652, |
|
146, |
|
660 |
|
] |
|
}, |
|
{ |
|
"text": "CALCULATION", |
|
"box": [ |
|
147, |
|
651, |
|
203, |
|
662 |
|
] |
|
} |
|
], |
|
"id": 70 |
|
}, |
|
{ |
|
"text": "Litchfield, J. T. and Wilcoxin F. , J. of Pharmacol", |
|
"box": [ |
|
228, |
|
638, |
|
700, |
|
661 |
|
], |
|
"linking": [ |
|
[ |
|
70, |
|
71 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Litchfield,", |
|
"box": [ |
|
228, |
|
641, |
|
327, |
|
661 |
|
] |
|
}, |
|
{ |
|
"text": "J.", |
|
"box": [ |
|
335, |
|
640, |
|
355, |
|
658 |
|
] |
|
}, |
|
{ |
|
"text": "T.", |
|
"box": [ |
|
363, |
|
641, |
|
381, |
|
655 |
|
] |
|
}, |
|
{ |
|
"text": "and", |
|
"box": [ |
|
391, |
|
641, |
|
420, |
|
655 |
|
] |
|
}, |
|
{ |
|
"text": "Wilcoxin", |
|
"box": [ |
|
429, |
|
641, |
|
511, |
|
656 |
|
] |
|
}, |
|
{ |
|
"text": "F.", |
|
"box": [ |
|
520, |
|
642, |
|
538, |
|
657 |
|
] |
|
}, |
|
{ |
|
"text": ",", |
|
"box": [ |
|
541, |
|
649, |
|
549, |
|
657 |
|
] |
|
}, |
|
{ |
|
"text": "J.", |
|
"box": [ |
|
554, |
|
641, |
|
572, |
|
654 |
|
] |
|
}, |
|
{ |
|
"text": "of", |
|
"box": [ |
|
582, |
|
640, |
|
604, |
|
658 |
|
] |
|
}, |
|
{ |
|
"text": "Pharmacol", |
|
"box": [ |
|
613, |
|
638, |
|
700, |
|
655 |
|
] |
|
} |
|
], |
|
"id": 71 |
|
}, |
|
{ |
|
"text": "and Exper. Ther. , 90: 99 , 1948.", |
|
"box": [ |
|
92, |
|
670, |
|
364, |
|
690 |
|
], |
|
"linking": [ |
|
[ |
|
70, |
|
72 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "and", |
|
"box": [ |
|
92, |
|
673, |
|
119, |
|
686 |
|
] |
|
}, |
|
{ |
|
"text": "Exper.", |
|
"box": [ |
|
126, |
|
673, |
|
182, |
|
687 |
|
] |
|
}, |
|
{ |
|
"text": "Ther.", |
|
"box": [ |
|
191, |
|
670, |
|
240, |
|
690 |
|
] |
|
}, |
|
{ |
|
"text": ",", |
|
"box": [ |
|
240, |
|
680, |
|
247, |
|
690 |
|
] |
|
}, |
|
{ |
|
"text": "90:", |
|
"box": [ |
|
254, |
|
672, |
|
282, |
|
689 |
|
] |
|
}, |
|
{ |
|
"text": "99", |
|
"box": [ |
|
284, |
|
672, |
|
302, |
|
690 |
|
] |
|
}, |
|
{ |
|
"text": ",", |
|
"box": [ |
|
303, |
|
677, |
|
313, |
|
690 |
|
] |
|
}, |
|
{ |
|
"text": "1948.", |
|
"box": [ |
|
318, |
|
670, |
|
364, |
|
688 |
|
] |
|
} |
|
], |
|
"id": 72 |
|
}, |
|
{ |
|
"text": "3.5 (3.1 to 3.9 g /kg", |
|
"box": [ |
|
239, |
|
703, |
|
420, |
|
721 |
|
], |
|
"linking": [ |
|
[ |
|
80, |
|
73 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "3.5", |
|
"box": [ |
|
239, |
|
705, |
|
267, |
|
719 |
|
] |
|
}, |
|
{ |
|
"text": "(3.1", |
|
"box": [ |
|
277, |
|
705, |
|
313, |
|
718 |
|
] |
|
}, |
|
{ |
|
"text": "to", |
|
"box": [ |
|
320, |
|
705, |
|
338, |
|
718 |
|
] |
|
}, |
|
{ |
|
"text": "3.9", |
|
"box": [ |
|
348, |
|
703, |
|
382, |
|
721 |
|
] |
|
}, |
|
{ |
|
"text": "g", |
|
"box": [ |
|
385, |
|
705, |
|
399, |
|
719 |
|
] |
|
}, |
|
{ |
|
"text": "/kg", |
|
"box": [ |
|
399, |
|
705, |
|
420, |
|
720 |
|
] |
|
} |
|
], |
|
"id": 73 |
|
}, |
|
{ |
|
"text": "Dr. H. J. Minnemeyer Ms. L. B. Gray", |
|
"box": [ |
|
345, |
|
863, |
|
530, |
|
895 |
|
], |
|
"linking": [ |
|
[ |
|
75, |
|
74 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "Dr.", |
|
"box": [ |
|
345, |
|
865, |
|
372, |
|
880 |
|
] |
|
}, |
|
{ |
|
"text": "H.", |
|
"box": [ |
|
380, |
|
865, |
|
397, |
|
879 |
|
] |
|
}, |
|
{ |
|
"text": "J.", |
|
"box": [ |
|
408, |
|
865, |
|
429, |
|
880 |
|
] |
|
}, |
|
{ |
|
"text": "Minnemeyer", |
|
"box": [ |
|
436, |
|
863, |
|
530, |
|
881 |
|
] |
|
}, |
|
{ |
|
"text": "Ms.", |
|
"box": [ |
|
346, |
|
880, |
|
373, |
|
893 |
|
] |
|
}, |
|
{ |
|
"text": "L.", |
|
"box": [ |
|
381, |
|
880, |
|
401, |
|
891 |
|
] |
|
}, |
|
{ |
|
"text": "B.", |
|
"box": [ |
|
408, |
|
881, |
|
429, |
|
892 |
|
] |
|
}, |
|
{ |
|
"text": "Gray", |
|
"box": [ |
|
440, |
|
881, |
|
476, |
|
895 |
|
] |
|
} |
|
], |
|
"id": 74 |
|
}, |
|
{ |
|
"text": "Copies to the Following:", |
|
"box": [ |
|
91, |
|
865, |
|
310, |
|
884 |
|
], |
|
"linking": [ |
|
[ |
|
75, |
|
74 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "Copies", |
|
"box": [ |
|
91, |
|
866, |
|
147, |
|
884 |
|
] |
|
}, |
|
{ |
|
"text": "to", |
|
"box": [ |
|
155, |
|
865, |
|
175, |
|
880 |
|
] |
|
}, |
|
{ |
|
"text": "the", |
|
"box": [ |
|
184, |
|
865, |
|
211, |
|
882 |
|
] |
|
}, |
|
{ |
|
"text": "Following:", |
|
"box": [ |
|
221, |
|
865, |
|
310, |
|
883 |
|
] |
|
} |
|
], |
|
"id": 75 |
|
}, |
|
{ |
|
"text": "LORILLARO RESEARCH CENTER", |
|
"box": [ |
|
80, |
|
946, |
|
202, |
|
956 |
|
], |
|
"linking": [], |
|
"label": "other", |
|
"words": [ |
|
{ |
|
"text": "LORILLARO", |
|
"box": [ |
|
80, |
|
946, |
|
123, |
|
956 |
|
] |
|
}, |
|
{ |
|
"text": "RESEARCH", |
|
"box": [ |
|
124, |
|
946, |
|
165, |
|
956 |
|
] |
|
}, |
|
{ |
|
"text": "CENTER", |
|
"box": [ |
|
168, |
|
946, |
|
202, |
|
956 |
|
] |
|
} |
|
], |
|
"id": 76 |
|
}, |
|
{ |
|
"text": "FORM 7 5/80", |
|
"box": [ |
|
676, |
|
946, |
|
732, |
|
958 |
|
], |
|
"linking": [], |
|
"label": "other", |
|
"words": [ |
|
{ |
|
"text": "FORM", |
|
"box": [ |
|
676, |
|
946, |
|
698, |
|
957 |
|
] |
|
}, |
|
{ |
|
"text": "7", |
|
"box": [ |
|
700, |
|
947, |
|
708, |
|
958 |
|
] |
|
}, |
|
{ |
|
"text": "5/80", |
|
"box": [ |
|
708, |
|
947, |
|
732, |
|
957 |
|
] |
|
} |
|
], |
|
"id": 77 |
|
}, |
|
{ |
|
"text": "of respiratory depression, constriction of blood vessels, and in- activity. Survivors recovered in 48 hours. The recommended safe dose for a single trial by inhalation in man is 0.3 mg.", |
|
"box": [ |
|
89, |
|
753, |
|
688, |
|
831 |
|
], |
|
"linking": [ |
|
[ |
|
34, |
|
78 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "of", |
|
"box": [ |
|
89, |
|
758, |
|
114, |
|
775 |
|
] |
|
}, |
|
{ |
|
"text": "respiratory", |
|
"box": [ |
|
122, |
|
758, |
|
223, |
|
773 |
|
] |
|
}, |
|
{ |
|
"text": "depression,", |
|
"box": [ |
|
230, |
|
757, |
|
329, |
|
774 |
|
] |
|
}, |
|
{ |
|
"text": "constriction", |
|
"box": [ |
|
334, |
|
756, |
|
447, |
|
776 |
|
] |
|
}, |
|
{ |
|
"text": "of", |
|
"box": [ |
|
457, |
|
757, |
|
475, |
|
772 |
|
] |
|
}, |
|
{ |
|
"text": "blood", |
|
"box": [ |
|
482, |
|
753, |
|
531, |
|
774 |
|
] |
|
}, |
|
{ |
|
"text": "vessels,", |
|
"box": [ |
|
538, |
|
753, |
|
611, |
|
773 |
|
] |
|
}, |
|
{ |
|
"text": "and", |
|
"box": [ |
|
620, |
|
756, |
|
651, |
|
773 |
|
] |
|
}, |
|
{ |
|
"text": "in-", |
|
"box": [ |
|
658, |
|
756, |
|
687, |
|
774 |
|
] |
|
}, |
|
{ |
|
"text": "activity.", |
|
"box": [ |
|
92, |
|
786, |
|
174, |
|
806 |
|
] |
|
}, |
|
{ |
|
"text": "Survivors", |
|
"box": [ |
|
193, |
|
786, |
|
278, |
|
803 |
|
] |
|
}, |
|
{ |
|
"text": "recovered", |
|
"box": [ |
|
285, |
|
786, |
|
367, |
|
803 |
|
] |
|
}, |
|
{ |
|
"text": "in", |
|
"box": [ |
|
377, |
|
788, |
|
395, |
|
802 |
|
] |
|
}, |
|
{ |
|
"text": "48", |
|
"box": [ |
|
404, |
|
785, |
|
421, |
|
803 |
|
] |
|
}, |
|
{ |
|
"text": "hours.", |
|
"box": [ |
|
429, |
|
785, |
|
485, |
|
803 |
|
] |
|
}, |
|
{ |
|
"text": "The", |
|
"box": [ |
|
501, |
|
784, |
|
532, |
|
804 |
|
] |
|
}, |
|
{ |
|
"text": "recommended", |
|
"box": [ |
|
539, |
|
782, |
|
640, |
|
803 |
|
] |
|
}, |
|
{ |
|
"text": "safe", |
|
"box": [ |
|
649, |
|
785, |
|
688, |
|
805 |
|
] |
|
}, |
|
{ |
|
"text": "dose", |
|
"box": [ |
|
91, |
|
813, |
|
130, |
|
830 |
|
] |
|
}, |
|
{ |
|
"text": "for", |
|
"box": [ |
|
138, |
|
813, |
|
167, |
|
830 |
|
] |
|
}, |
|
{ |
|
"text": "a", |
|
"box": [ |
|
175, |
|
816, |
|
185, |
|
830 |
|
] |
|
}, |
|
{ |
|
"text": "single", |
|
"box": [ |
|
194, |
|
811, |
|
250, |
|
829 |
|
] |
|
}, |
|
{ |
|
"text": "trial", |
|
"box": [ |
|
258, |
|
813, |
|
303, |
|
831 |
|
] |
|
}, |
|
{ |
|
"text": "by", |
|
"box": [ |
|
310, |
|
814, |
|
330, |
|
829 |
|
] |
|
}, |
|
{ |
|
"text": "inhalation", |
|
"box": [ |
|
338, |
|
813, |
|
430, |
|
831 |
|
] |
|
}, |
|
{ |
|
"text": "in", |
|
"box": [ |
|
440, |
|
811, |
|
461, |
|
828 |
|
] |
|
}, |
|
{ |
|
"text": "man", |
|
"box": [ |
|
466, |
|
813, |
|
493, |
|
828 |
|
] |
|
}, |
|
{ |
|
"text": "is", |
|
"box": [ |
|
503, |
|
813, |
|
521, |
|
828 |
|
] |
|
}, |
|
{ |
|
"text": "0.3", |
|
"box": [ |
|
529, |
|
813, |
|
557, |
|
828 |
|
] |
|
}, |
|
{ |
|
"text": "mg.", |
|
"box": [ |
|
563, |
|
816, |
|
594, |
|
831 |
|
] |
|
} |
|
], |
|
"id": 78 |
|
}, |
|
{ |
|
"text": "This compound appears to act as a CNS depressant with symptons", |
|
"box": [ |
|
135, |
|
728, |
|
704, |
|
749 |
|
], |
|
"linking": [ |
|
[ |
|
34, |
|
79 |
|
] |
|
], |
|
"label": "answer", |
|
"words": [ |
|
{ |
|
"text": "This", |
|
"box": [ |
|
135, |
|
733, |
|
176, |
|
747 |
|
] |
|
}, |
|
{ |
|
"text": "compound", |
|
"box": [ |
|
184, |
|
733, |
|
257, |
|
747 |
|
] |
|
}, |
|
{ |
|
"text": "appears", |
|
"box": [ |
|
264, |
|
732, |
|
330, |
|
747 |
|
] |
|
}, |
|
{ |
|
"text": "to", |
|
"box": [ |
|
339, |
|
730, |
|
359, |
|
745 |
|
] |
|
}, |
|
{ |
|
"text": "act", |
|
"box": [ |
|
366, |
|
730, |
|
393, |
|
745 |
|
] |
|
}, |
|
{ |
|
"text": "as", |
|
"box": [ |
|
401, |
|
730, |
|
423, |
|
745 |
|
] |
|
}, |
|
{ |
|
"text": "a", |
|
"box": [ |
|
429, |
|
733, |
|
443, |
|
747 |
|
] |
|
}, |
|
{ |
|
"text": "CNS", |
|
"box": [ |
|
446, |
|
729, |
|
477, |
|
746 |
|
] |
|
}, |
|
{ |
|
"text": "depressant", |
|
"box": [ |
|
485, |
|
729, |
|
577, |
|
749 |
|
] |
|
}, |
|
{ |
|
"text": "with", |
|
"box": [ |
|
585, |
|
729, |
|
621, |
|
746 |
|
] |
|
}, |
|
{ |
|
"text": "symptons", |
|
"box": [ |
|
631, |
|
728, |
|
704, |
|
746 |
|
] |
|
} |
|
], |
|
"id": 79 |
|
}, |
|
{ |
|
"text": "LD50 (95% CONFIDENCE LIMITS)", |
|
"box": [ |
|
82, |
|
711, |
|
203, |
|
723 |
|
], |
|
"linking": [ |
|
[ |
|
80, |
|
73 |
|
] |
|
], |
|
"label": "question", |
|
"words": [ |
|
{ |
|
"text": "LD50", |
|
"box": [ |
|
82, |
|
712, |
|
103, |
|
723 |
|
] |
|
}, |
|
{ |
|
"text": "(95%", |
|
"box": [ |
|
102, |
|
712, |
|
122, |
|
723 |
|
] |
|
}, |
|
{ |
|
"text": "CONFIDENCE", |
|
"box": [ |
|
123, |
|
711, |
|
175, |
|
722 |
|
] |
|
}, |
|
{ |
|
"text": "LIMITS)", |
|
"box": [ |
|
175, |
|
711, |
|
203, |
|
721 |
|
] |
|
} |
|
], |
|
"id": 80 |
|
} |
|
] |
|
} |