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Robert J. Mayer, MD Faculty Vice President for Academic Affairs Institute Physician Stephen B. Kay Family Professor of Medicine, Harvard Medical School Anal Cancer Biliary Cancer Gastrointestinal Carcinoid Tumor Neuroendocrine/Carcinoid Tumors Stomach (Gastric) Cancer Office Phone Number617-632-3474 Dr. Mayer received his MD from Harvard Medical School in 1969, and postgraduate training in internal medicine at Mount Sinai Hospital, New York City. After fellowships in hematology and oncology at the National Cancer Institute and Dana-Farber Cancer Institute, he joined Dana-Farber in 1974. In 1997, he was president of the American Society of Clinical Oncology. Dr. Mayer currently serves as Faculty Vice President for Academic Affairs at Dana-Farber Cancer Institute and Faculty Associate Dean for Admissions at Harvard Medical School. Hematology, 1976 Internal Medicine, Nephrology, 1973 Medical Oncology, 1975 Dana-Farber Cancer Institute, Hematology & Medical Oncology National Cancer Institute, Medical Oncology Mount Sinai Hospital, Internal Medicine Recent Awards: Distinguished Achievement Award, American Society of Clinical Oncology 2019 Giants of Cancer, Gastrointestinal Cancer 2015 Ellen and Stephen Fine Award for Outstanding Teaching in Cancer Medicine, Dana-Farber Cancer Institute 2010 Sword of Hope Award, American Cancer Society Massachusetts Division 1995 George W. Thorn Award for Outstanding Contribution to Clinical Education 1990 View Dr. Mayer's Research Multidisciplinary Research in Gastrointestinal Cancer Gastrointestinal cancer ranks second only to respiratory cancer in the number of new cases and annual deaths in the United States each year. The term gastrointestinal cancer refers to malignant conditions of the esophagus, stomach, liver, biliary system, pancreas, small bowel, large bowel (i.e., colon and rectum), and anus.The Center for Gastrointestinal Oncology, directed by Dr. Mayer, is a multidisciplinary program to study this group of diseases. Our efforts include the identification and counseling of families at high risk of developing such disorders, the study of medical interventions to prevent the diseases, screening techniques to detect them at a preclinical stage, and the development of innovative treatment plans for diagnosed patients. Such efforts involve the participation of medical, radiation, and surgical oncologists, pathologists, gastroenterologists, social workers, and genetic counselors.The Gastrointestinal Cancer Committee of the Cancer and Leukemia Group B, chaired by Dr. Mayer, is a multi-institutional collaboration supported by the National Cancer Institute. This research organization designs clinical trials conducted at DFCI and elsewhere throughout the United States.We also work regularly with pharmaceutical and biotechnology companies to examine experimental forms of therapy. Clinical trials are available for patients with each of the malignant conditions that gastrointestinal cancer comprises.Our work has been instrumental in studies which have defined optimal post-surgical (i.e., adjuvant) treatment for colon and rectal cancer and newer approaches to localized and advanced pancreatic cancer. In addition, Dr. Mayer has brought such new compounds as cetuximab to Dana-Farber for clinical testing. View Dr. Mayer's Publications Programmatic Precision Oncology Decision Support for Patients With Gastrointestinal Cancer. JCO Precis Oncol. 2023 Jan; 7:e2200342. Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Natl Cancer Inst. 2022 03 08; 114(3):427-435. Age and comorbidity association with survival outcomes in metastatic colorectal cancer: CALGB 80405 analysis. J Geriatr Oncol. 2022 05; 13(4):469-479. Plasma 25-Hydroxyvitamin D Levels and Survival in Patients with Advanced or Metastatic Colorectal Cancer: Findings from CALGB/SWOG 80405 (Alliance). Clin Cancer Res. 2019 12 15; 25(24):7497-7505. Associations of Physical Activity With Survival and Progression in Metastatic Colorectal Cancer: Results From Cancer and Leukemia Group B (Alliance)/SWOG 80405. J Clin Oncol. 2019 10 10; 37(29):2620-2631. Reasons of reduced physical activity in preconception and pregnancy. Minerva Med. 2019 Jul 09. Prognostic association of PTGS2 (COX-2) over-expression according to BRAF mutation status in colorectal cancer: Results from two prospective cohorts and CALGB 89803 (Alliance) trial. Eur J Cancer. 2019 04; 111:82-93. Dietary Insulin Load and Cancer Recurrence and Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 (Alliance). J Natl Cancer Inst. 2019 02 01; 111(2):170-179. Safety of trifluridine/tipiracil in an open-label expanded-access program in elderly and younger patients with metastatic colorectal cancer. Cancer Chemother Pharmacol. 2018 12; 82(6):961-969. NCCN Guidelines Insights: Colorectal Cancer Screening, Version 1.2018. J Natl Compr Canc Netw. 2018 08; 16(8):939-949. Associations of artificially sweetened beverage intake with disease recurrence and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance). PLoS One. 2018; 13(7):e0199244. Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine. Cancer Discov. 2018 09; 8(9):1096-1111. Grain Intake and Clinical Outcome in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). JNCI Cancer Spectr. 2018 Feb; 2(2):pky017. Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol. 2018 04 10; 36(11):1112-1120. NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 3.2017. J Natl Compr Canc Netw. 2017 12; 15(12):1465-1475. Adjuvant Chemoradiotherapy With Epirubicin, Cisplatin, and Fluorouracil Compared With Adjuvant Chemoradiotherapy With Fluorouracil and Leucovorin After Curative Resection of Gastric Cancer: Results From CALGB 80101 (Alliance). J Clin Oncol. 2017 Nov 10; 35(32):3671-3677. Predicted vitamin D status and colon cancer recurrence and mortality in CALGB 89803 (Alliance). Ann Oncol. 2017 Jun 01; 28(6):1359-1367. Development and Validation of the PREMM5 Model for Comprehensive Risk Assessment of Lynch Syndrome. J Clin Oncol. 2017 Jul 01; 35(19):2165-2172. Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer. J Clin Oncol. 2017 Apr 01; 35(10):1086-1095. Reply to L. Casadaban et al. J Clin Oncol. 2017 04 20; 35(12):1373-1374. Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance). J Clin Oncol. 2016 09 01; 34(25):3047-53. CALGB 80403 (Alliance)/E1206: A Randomized Phase II Study of Three Chemotherapy Regimens Plus Cetuximab in Metastatic Esophageal and Gastroesophageal Junction Cancers. J Clin Oncol. 2016 08 10; 34(23):2736-42. Safety, Costs, and Efficacy of Rapid Drug Desensitizations to Chemotherapy and Monoclonal Antibodies. J Allergy Clin Immunol Pract. 2016 May-Jun; 4(3):497-504. Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). J Clin Oncol. 2015 Nov 01; 33(31):3598-607. Colorectal Cancer Screening, Version 1.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8):959-68; quiz 968. Randomized trial of TAS-102 for refractory metastatic colorectal cancer. N Engl J Med. 2015 May 14; 372(20):1909-19. Pharmacogenetic Analysis of INT 0144 Trial: Association of Polymorphisms with Survival and Toxicity in Rectal Cancer Patients Treated with 5-FU and Radiation. Clin Cancer Res. 2015 Apr 01; 21(7):1583-90. Aspirin and COX-2 inhibitor use in patients with stage III colon cancer. J Natl Cancer Inst. 2015 Jan; 107(1):345. Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway. J Biol Chem. 2014 Sep 05; 289(36):24944-55. Sugar-sweetened beverage intake and cancer recurrence and survival in CALGB 89803 (Alliance). PLoS One. 2014; 9(6):e99816. Progress against GI cancer during the American Society of Clinical Oncology's first 50 years. J Clin Oncol. 2014 May 20; 32(15):1521-30. Colorectal cancer screening. J Natl Compr Canc Netw. 2013 Dec 01; 11(12):1538-75. Predictive and prognostic analysis of PIK3CA mutation in stage III colon cancer intergroup trial. J Natl Cancer Inst. 2013 Dec 04; 105(23):1789-98. Anal carcinoma: impact of TN category of disease on survival, disease relapse, and colostomy failure in US Gastrointestinal Intergroup RTOG 98-11 phase 3 trial. Int J Radiat Oncol Biol Phys. 2013 Nov 15; 87(4):638-45. Impact of physical activity after cancer diagnosis on survival in patients with recurrent colon cancer: Findings from CALGB 89803/Alliance. Clin Colorectal Cancer. 2013 Dec; 12(4):233-8. Association of TP53 mutational status and gender with survival after adjuvant treatment for stage III colon cancer: results of CALGB 89803. Clin Cancer Res. 2013 Oct 15; 19(20):5777-87. Reply to A. Grothey et al and R.S. Midgley et al. J Clin Oncol. 2013 Apr 20; 31(12):1612-3. Phase I study of sorafenib in combination with everolimus (RAD001) in patients with advanced neuroendocrine tumors. Cancer Chemother Pharmacol. 2013 May; 71(5):1241-6. Long-term update of US GI intergroup RTOG 98-11 phase III trial for anal carcinoma: survival, relapse, and colostomy failure with concurrent chemoradiation involving fluorouracil/mitomycin versus fluorouracil/cisplatin. J Clin Oncol. 2012 Dec 10; 30(35):4344-51. Dietary glycemic load and cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Natl Cancer Inst. 2012 Nov 21; 104(22):1702-11. Clinical practice guidelines for cancer care: utilization and expectations of the practicing oncologist. J Oncol Pract. 2012 Nov; 8(6):350-3, 2 p following 353. Oxaliplatin as part of adjuvant therapy for colon cancer: more complicated than once thought. J Clin Oncol. 2012 Sep 20; 30(27):3325-7. Perspective: a culture of respect, part 1: the nature and causes of disrespectful behavior by physicians. Acad Med. 2012 Jul; 87(7):845-52. Perspective: a culture of respect, part 2: creating a culture of respect. Acad Med. 2012 Jul; 87(7):853-8. Disability in women suffering from interstitial cystitis/bladder pain syndrome. BJU Int. 2013 Jan; 111(1):114-21. Locally advanced anaplastic pancreatic adenocarcinoma with initial response to FOLFIRINOX and rapid progression after five months. Pancreatology. 2012 Jan-Feb; 12(1):35-8. Predictive and prognostic roles of BRAF mutation in stage III colon cancer: results from intergroup trial CALGB 89803. Clin Cancer Res. 2012 Feb 01; 18(3):890-900. Relationship between statin use and colon cancer recurrence and survival: results from CALGB 89803. J Natl Cancer Inst. 2011 Oct 19; 103(20):1540-51. Documenting the natural history of patients with resected stage II adenocarcinoma of the colon after random assignment to adjuvant treatment with edrecolomab or observation: results from CALGB 9581. J Clin Oncol. 2011 Aug 10; 29(23):3146-52. Microsatellite instability and loss of heterozygosity at chromosomal location 18q: prospective evaluation of biomarkers for stages II and III colon cancer--a study of CALGB 9581 and 89803. J Clin Oncol. 2011 Aug 10; 29(23):3153-62. Postoperative adjuvant chemoradiation for gastric or gastroesophageal junction (GEJ) adenocarcinoma using epirubicin, cisplatin, and infusional (CI) 5-FU (ECF) before and after CI 5-FU and radiotherapy (CRT) compared with bolus 5-FU/LV before and after CRT: Intergroup trial CALGB 80101. J Clin Oncol. 2011 May 20; 29(15_suppl):4003. Long-term update of U.S. GI intergroup RTOG 98-11 phase III trial for anal carcinoma: Disease-free and overall survival with RT+5FU-mitomycin versus RT+5FU-cisplatin. J Clin Oncol. 2011 May 20; 29(15_suppl):4005. Long-term update of U.S. GI Intergroup RTOG 98-11 phase III trial for anal carcinoma: Comparison of concurrent chemoradiation with 5FU-mitomycin versus 5FU-cisplatin for disease-free and overall survival. J Clin Oncol. 2011 Feb; 29(4_suppl):367. A phase 2 trial of gemcitabine, 5-fluorouracil, and radiation therapy in locally advanced nonmetastatic pancreatic adenocarcinoma : cancer and Leukemia Group B (CALGB) 80003. Cancer. 2011 Jun 15; 117(12):2620-8. Prognostic factors derived from a prospective database dictate clinical biology of anal cancer: the intergroup trial (RTOG 98-11). Cancer. 2010 Sep 01; 116(17):4007-13. Multivitamin use is not associated with cancer recurrence or survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol. 2010 Oct 01; 28(28):4354-63. Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303). J Clin Oncol. 2010 Aug 01; 28(22):3617-22. By the way, doctor. I read that President Obama had a virtual colonoscopy. Is this the colon cancer screening test that everybody should be getting instead of a regular colonoscopy? I thought it was kind of experimental. Harv Health Lett. 2010 Jun; 35(8):8. A step forward in the treatment of advanced biliary tract cancer. N Engl J Med. 2010 Apr 08; 362(14):1335-7. The American Society of Clinical Oncology Cancer Foundation Grants Program: a 25-year report and a look toward the future. J Clin Oncol. 2010 Mar 20; 28(9):1616-21. NCCN clinical practice guidelines in oncology. Colorectal cancer screening. J Natl Compr Canc Netw. 2010 Jan; 8(1):8-61. KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803. Clin Cancer Res. 2009 Dec 01; 15(23):7322-9. Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904. J Clin Oncol. 2009 Nov 20; 27(33):5506-12. KRAS mutation, cancer recurrence, and patient survival in stage III colon cancer: Findings from CALGB 89803. J Clin Oncol. 2009 May 20; 27(15_suppl):4037. Presence of 18q loss of heterozygosity (LOH) and disease-free and overall survival in stage II colon cancer: CALGB Protocol 9581. J Clin Oncol. 2009 May 20; 27(15_suppl):4012. By the way, doctor. We have screening tests for other cancers. How about pancreatic cancer? Harv Health Lett. 2009 May; 34(7):1. Sexual functioning, catastrophizing, depression, and pain, as predictors of quality of life in women with interstitial cystitis/painful bladder syndrome. Urology. 2009 May; 73(5):987-92. A compendium of potential biomarkers of pancreatic cancer. PLoS Med. 2009 Apr 07; 6(4):e1000046. p27Kip1 in stage III colon cancer: implications for outcome following adjuvant chemotherapy in cancer and leukemia group B protocol 89803. Clin Cancer Res. 2009 Mar 15; 15(6):2116-22. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, fluorouracil, and leucovorin in stage III colon cancer: Cancer and Leukemia Group B Protocol 89803. J Clin Oncol. 2009 Apr 10; 27(11):1814-21. Targeted therapy for advanced colorectal cancer--more is not always better. N Engl J Med. 2009 Feb 05; 360(6):623-5. Weekly docetaxel, cisplatin, and irinotecan (TPC): results of a multicenter phase II trial in patients with metastatic esophagogastric cancer. Ann Oncol. 2009 Mar; 20(3):475-80. US intergroup anal carcinoma trial: tumor diameter predicts for colostomy. J Clin Oncol. 2009 Mar 01; 27(7):1116-21. Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2009 Feb 10; 27(5):812-26. Impact of body mass index and weight change after treatment on cancer recurrence and survival in patients with stage III colon cancer: findings from Cancer and Leukemia Group B 89803. J Clin Oncol. 2008 Sep 01; 26(25):4109-15. Patients with acute myeloid leukemia and RAS mutations benefit most from postremission high-dose cytarabine: a Cancer and Leukemia Group B study. J Clin Oncol. 2008 Oct 01; 26(28):4603-9. Local excision of distal rectal cancer: an update of cancer and leukemia group B 8984. Dis Colon Rectum. 2008 Aug; 51(8):1185-91; discussion 1191-4. Association of family history with cancer recurrence and survival among patients with stage III colon cancer. JAMA. 2008 Jun 04; 299(21):2515-23. The impact of smoking on cancer recurrence and survival in patients with stage III colon cancer: Findings from intergroup trial CALGB 89803. J Clin Oncol. 2008 May 20; 26(15_suppl):4039. Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281). J Clin Oncol. 2008 Jul 01; 26(19):3229-34. Systemic treatment of colorectal cancer. Gastroenterology. 2008 May; 134(5):1296-310. By the way, doctor. Cancer of the small intestine. Harv Health Lett. 2008 May; 33(7):7. Fluorouracil, mitomycin, and radiotherapy vs fluorouracil, cisplatin, and radiotherapy for carcinoma of the anal canal: a randomized controlled trial. JAMA. 2008 Apr 23; 299(16):1914-21. Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781. J Clin Oncol. 2008 Mar 01; 26(7):1086-92. Followup of patients with interstitial cystitis responsive to treatment with intravesical bacillus Calmette-Guerin or placebo. J Urol. 2008 Feb; 179(2):552-5. Clinical cancer advances 2007: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2008 Jan 10; 26(2):313-25. A phase II prospective multi-institutional trial of adjuvant active specific immunotherapy following curative resection of colorectal cancer hepatic metastases: cancer and leukemia group B study 89903. Ann Surg Oncol. 2008 Jan; 15(1):158-64. Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer? J Clin Oncol. 2007 Sep 20; 25(27):4165-7. Association of dietary patterns with cancer recurrence and survival in patients with stage III colon cancer. JAMA. 2007 Aug 15; 298(7):754-64. Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J Clin Oncol. 2007 Aug 10; 25(23):3456-61. Did patients with interstitial cystitis who failed to respond to initial treatment with bacillus Calmette-Guerin or placebo in a randomized clinical trial benefit from a second course of open label bacillus Calmette-Guerin? J Urol. 2007 Sep; 178(3 Pt 1):886-90. Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer. Ann Oncol. 2007 Jul; 18(7):1185-9. Sexual function is a determinant of poor quality of life for women with treatment refractory interstitial cystitis. J Urol. 2007 May; 177(5):1832-6. Adjuvant treatment of colorectal cancer. CA Cancer J Clin. 2007 May-Jun; 57(3):168-85. Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer. Cancer Chemother Pharmacol. 2007 Oct; 60(5):661-70. Multicenter phase II and translational study of cetuximab in metastatic colorectal carcinoma refractory to irinotecan, oxaliplatin, and fluoropyrimidines. J Clin Oncol. 2006 Oct 20; 24(30):4914-21. The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer. Gastroenterology. 2007 Jan; 132(1):127-38. Systemic treatment of patients who have colorectal cancer and inflammatory bowel disease. Gastroenterol Clin North Am. 2006 Sep; 35(3):713-27. Development of glomerulations in younger women with interstitial cystitis. Urology. 2006 Aug; 68(2):253-6. Phase III trial of fluorouracil-based chemotherapy regimens plus radiotherapy in postoperative adjuvant rectal cancer: GI INT 0144. J Clin Oncol. 2006 Aug 01; 24(22):3542-7. Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol. 2006 Aug 01; 24(22):3535-41. ECOG E3201: Intergroup randomized phase III study of postoperative irinotecan, 5- fluorouracil (FU), leucovorin (LV) (FOLFIRI) vs oxaliplatin, FU/LV (FOLFOX) vs FU/LV for patients (pts) with stage II/ III rectal cancer receiving either pre or postoperative radiation (RT)/ FU. J Clin Oncol. 2006 Jun 20; 24(18_suppl):3526. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, 5-fluorouracil and leucovorin in stage III colon cancer. J Clin Oncol. 2006 Jun 20; 24(18_suppl):10003. Intergroup RTOG 98-11: A phase III randomized study of 5-fluorouracil (5-FU), mitomycin, and radiotherapy versus 5-fluorouracil, cisplatin and radiotherapy in carcinoma of the anal canal. J Clin Oncol. 2006 Jun 20; 24(18_suppl):4009. Cancer and leukemia group B gastrointestinal cancer committee. Clin Cancer Res. 2006 Jun 01; 12(11 Pt 2):3589s-95s. Fifty years of clinical research by the leukemia committee of the cancer and leukemia group B. 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Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of Cancer and Leukemia Group B Trial 80001. J Clin Oncol. 2006 Feb 20; 24(6):878-83. Clinical Cancer Advances 2005: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology. J Clin Oncol. 2006 Jan 01; 24(1):190-205. Phase III study of fluorouracil, leucovorin, and levamisole in high-risk stage II and III colon cancer: final report of Intergroup 0089. J Clin Oncol. 2005 Dec 01; 23(34):8671-8. Colon cancer survival is associated with decreasing ratio of metastatic to examined lymph nodes. J Clin Oncol. 2005 Dec 01; 23(34):8706-12. A phase II trial of irinotecan in patients with previously untreated advanced esophageal and gastric adenocarcinoma. Dig Dis Sci. 2005 Dec; 50(12):2218-23. Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study. J Clin Oncol. 2005 Aug 20; 23(24):5705-17. Influence of regular aspirin use on survival for patients with stage III colon cancer: Findings from Intergroup trial CALGB 89803. J Clin Oncol. 2005 Jun; 23(16_suppl):3530. The impact of physical activity on patients with stage III colon cancer: Findings from Intergroup trial CALGB 89803. J Clin Oncol. 2005 Jun; 23(16_suppl):3534. Factors predicting willingness to participate in cancer genetic epidemiologic research. J Clin Oncol. 2005 Jun; 23(16_suppl):6007. Consistent response to treatment with cetuximab monotherapy in patients with metastatic colorectal cancer. J Clin Oncol. 2005 Jun; 23(16_suppl):3536. Analysis of EGFR status in metastatic colorectal cancer patients treated with cetuximab monotherapy. J Clin Oncol. 2005 Jun; 23(16_suppl):3595. A randomized controlled trial of intravesical bacillus calmette-guerin for treatment refractory interstitial cystitis. J Urol. 2005 Apr; 173(4):1186-91. Phase III Southwest Oncology Group 9415/Intergroup 0153 randomized trial of fluorouracil, leucovorin, and levamisole versus fluorouracil continuous infusion and levamisole for adjuvant treatment of stage III and high-risk stage II colon cancer. J Clin Oncol. 2005 Mar 20; 23(9):1819-25. Systemic therapy for colorectal cancer. N Engl J Med. 2005 Feb 03; 352(5):476-87. Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers. Int J Cancer. 2004 Dec 10; 112(5):754-9. Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study. J Clin Oncol. 2005 Jan 20; 23(3):482-93. APC promoter hypermethylation contributes to the loss of APC expression in colorectal cancers with allelic loss on 5q. 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Post-remission therapy with 4 cycles of intermediate (I) or high-dose (HD) cytarabine (AC) or autologous hematopoietic stem cell transplantation (ASCT) for acute myeloid leukemia (AML) patients <60 years with normal cytogenetics: A Cancer and Leukemia Group B (CALGB) Study. J Clin Oncol. 2004 Jul 15; 22(14_suppl):6542. A randomized phase II study of gemcitabine/cisplatin, gemcitabine fixed dose rate infusion, gemcitabine/docetaxel, or gemcitabine/irinotecan in patients with metastatic pancreatic cancer (CALGB 89904). J Clin Oncol. 2004 Jul 15; 22(14_suppl):4011. Two steps forward in the treatment of colorectal cancer. N Engl J Med. 2004 Jun 03; 350(23):2406-8. Frequent inactivation of PTEN by promoter hypermethylation in microsatellite instability-high sporadic colorectal cancers. Cancer Res. 2004 May 01; 64(9):3014-21. Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis. J Clin Oncol. 2004 May 15; 22(10):1785-96. Gastrointestinal cancer in older patients. Semin Oncol. 2004 Apr; 31(2):206-19. Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461. J Clin Oncol. 2004 Mar 15; 22(6):1087-94. Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol. 2004 Apr 01; 22(7):1201-8. Differences in prognostic factors and outcomes in African Americans and whites with acute myeloid leukemia. Blood. 2004 Jun 01; 103(11):4036-42. Impact of body mass index on outcomes and treatment-related toxicity in patients with stage II and III rectal cancer: findings from Intergroup Trial 0114. J Clin Oncol. 2004 Feb 15; 22(4):648-57. Evaluation of microsatellite instability, hMLH1 expression and hMLH1 promoter hypermethylation in defining the MSI phenotype of colorectal cancer. Cancer Biol Ther. 2004 Jan; 3(1):73-8. Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461. Ann Hematol. 2004; 83 Suppl 1:S84-5. A phase II study of docetaxel in patients with metastatic carcinoid tumors. Cancer Invest. 2004; 22(3):353-9. Impact of hospital procedure volume on surgical operation and long-term outcomes in high-risk curatively resected rectal cancer: findings from the Intergroup 0114 Study. J Clin Oncol. 2004 Jan 01; 22(1):166-74. Esophageal cancer. N Engl J Med. 2003 Dec 04; 349(23):2241-52. Association of hospital procedure volume and outcomes in patients with colon cancer at high risk for recurrence. Ann Intern Med. 2003 Oct 21; 139(8):649-57. Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114. J Clin Oncol. 2003 Oct 01; 21(19):3623-8. Influence of body mass index on outcomes and treatment-related toxicity in patients with colon carcinoma. Cancer. 2003 Aug 01; 98(3):484-95. 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A phase II study of modified deGramont 5-fluorouracil, leucovorin, and oxaliplatin in previously treated patients with metastatic colorectal cancer. Cancer Invest. 2003; 21(4):505-11. Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461. Int J Oncol. 2002 Nov; 21(5):1041-51. Acute diarrhea during adjuvant therapy for rectal cancer: a detailed analysis from a randomized intergroup trial. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):409-13. Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis. Int J Radiat Oncol Biol Phys. 2002 Oct 01; 54(2):386-96. A phase II study of troglitazone, an activator of the PPARgamma receptor, in patients with chemotherapy-resistant metastatic colorectal cancer. Cancer J. 2002 Sep-Oct; 8(5):395-9. Outcomes and toxicity in african-american and caucasian patients in a randomized adjuvant chemotherapy trial for colon cancer. J Natl Cancer Inst. 2002 Aug 07; 94(15):1160-7. Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood. 2002 Dec 15; 100(13):4325-36. A phase II trial of gemcitabine in patients with advanced hepatocellular carcinoma. Cancer. 2002 Jun 15; 94(12):3186-91. Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control--final report of intergroup 0114. J Clin Oncol. 2002 Apr 01; 20(7):1744-50. Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089. Ann Intern Med. 2002 Feb 19; 136(4):261-9. Merkel cell carcinoma. J Clin Oncol. 2002 Jan 15; 20(2):588-98. A Phase II study of gemcitabine and docetaxel in patients with metastatic pancreatic carcinoma. Cancer. 2002 Jan 01; 94(1):97-103. Oral versus intravenous fluoropyrimidines for advanced colorectal cancer: by either route, it's all the same. J Clin Oncol. 2001 Nov 01; 19(21):4093-6. Fluorouracil modulation in colorectal cancer: lack of improvement with N -phosphonoacetyl- l -aspartic acid or oral leucovorin or interferon, but enhanced therapeutic index with weekly 24-hour infusion schedule--an Eastern Cooperative Oncology Group/Cancer and Leukemia Group B Study. J Clin Oncol. 2001 May 01; 19(9):2413-21. CALGB 9380: a prospective trial of the feasibility of thoracoscopy/laparoscopy in staging esophageal cancer. Ann Thorac Surg. 2001 Apr; 71(4):1073-9. Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma. Cancer. 2001 Apr 01; 91(7):1256-63. Oxaliplatin-induced Evan's syndrome. Br J Cancer. 2001 Feb 02; 84(3):441. Efficacy of neo- and adjuvant treatment modalities in gastrointestinal cancer patients. Swiss Surg. 2001; 7(6):239-42. Attitudes and practices among pediatric oncologists regarding end-of-life care: results of the 1998 American Society of Clinical Oncology survey. J Clin Oncol. 2001 Jan 01; 19(1):205-12. Impact of number of nodes retrieved on outcome in patients with rectal cancer. J Clin Oncol. 2001 Jan 01; 19(1):157-63. Attitudes and practices of U.S. oncologists regarding euthanasia and physician-assisted suicide. Ann Intern Med. 2000 Oct 03; 133(7):527-32. Moving beyond fluorouracil for colorectal cancer. N Engl J Med. 2000 Sep 28; 343(13):963-4. Diagnostic dilemmas in oncology. Case 3. Metastatic ovarian cancer simulating colon cancer. J Clin Oncol. 2000 Sep; 18(17):3189-92. Anal carcinoma: histology, staging, epidemiology, treatment. Curr Opin Oncol. 2000 Jul; 12(4):345-52. Chemoprevention of colorectal cancer. N Engl J Med. 2000 Jun 29; 342(26):1960-8. 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N Engl J Med. 1997 Sep 25; 337(13):935; author reply 937-8. Secondary cytogenetic changes in acute promyelocytic leukemia--prognostic importance in patients treated with chemotherapy alone and association with the intron 3 breakpoint of the PML gene: a Cancer and Leukemia Group B study. J Clin Oncol. 1997 May; 15(5):1786-95. Extramedullary leukemia adversely affects hematologic complete remission rate and overall survival in patients with t(8;21)(q22;q22): results from Cancer and Leukemia Group B 8461. J Clin Oncol. 1997 Feb; 15(2):466-75. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology. 1997 Feb; 112(2):594-642. Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol. 1997 Jan; 15(1):246-50. Acute myeloid leukemia-type chemotherapy for newly diagnosed patients without antecedent cytopenias having myelodysplastic syndrome as defined by French-American-British criteria: a Cancer and Leukemia Group B Study. J Clin Oncol. 1996 Sep; 14(9):2486-94. The status of the medical oncology workforce a report from the ad hoc committee of the American Society of Clinical Oncology. J Clin Oncol. 1996; 14:2612-2621. Adjuvant chemotherapy for colon and rectal cancer. Semin Oncol. 1995 Oct; 22(5):472-87. Summary of the Second International Conference on Biology, Prevention and Treatment of Gastrointestinal Malignancies. Ann Oncol. 1995 Sep; 6(7):645-9. Gastric carcinoma. N Engl J Med. 1995 Jul 06; 333(1):32-41. Morphologic characteristics of erythroleukemia (acute myeloid leukemia; FAB-M6): a CALGB study. Am J Hematol. 1995 May; 49(1):29-38. Clinical pharmacology of cytarabine in patietns with acute myeloid leukemia: a Cancer and Leukemia Group B study. Cancer Chemother and Pharmacol. 1995; 36:425-430. Clinical pharmacology of cytarabine in patients with acute myeloid leukemia: a Cancer and Leukemia Group B study. Cancer Chemother and Pharmacol. 1995; 36:425-430. A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: follow-up report. J Hepatic Biliary Pancreatic Surg. 1995; 2:122-125. Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B. N Engl J Med. 1994 Oct 06; 331(14):896-903. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med. 1994 Aug 25; 331(8):502-7. The use of serologic tumor markers in gastrointestinal malignancies. Hematol Oncol Clin North Am. 1994 Jun; 8(3):533-53. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994 Mar 15; 83(6):1603-11. Cigarette smoking and risk of acute leukemia: associations with morphology and cytogenetic abnormalities in bone marrow. J Natl Cancer Inst. 1993 Dec 15; 85(24):1994-2003. Primary central nervous system lymphoma. Ann Intern Med. 1993 Dec 01; 119(11):1093-104. Preoperative and postoperative combination chemotherapy for potentially resectable gastric carcinoma. J Natl Cancer Inst. 1993 Nov 17; 85(22):1839-44. Neoadjuvant therapy for unresectable pancreatic adenocarcinoma. Arch Surg. 1993 May; 128(5):559-64. Recombinant human gamma interferon administered by continuous intravenous infusion in acute myelogenous leukemia and myelodysplastic syndromes. Am J Clin Oncol. 1993 Apr; 16(2):159-63. Overview: the changing nature of esophageal cancer. Chest. 1993 Apr; 103(4 Suppl):404S-405S. Treatment of the newly diagnosed adult with de novo acute myeloid leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):47-64. The approach to the elderly patient with acute myeloid leukemia. Hematol Oncol Clin North Am. 1993 Feb; 7(1):65-79. Adjuvant Chemotherapy for Colon and Rectal Cancer. Semin Radiat Oncol. 1993 Jan; 3(1):29-41. Some considerations concerning the dose and schedule of 5FU and leucovorin: toxicities of two dose schedules from the intergroup colon adjuvant trial (INT-0089). Adv Exp Med Biol. 1993; 339:51-4; discussion 55-6. Chemotherapy for metastatic colorectal cancer. Cancer. 1992 Sep 01; 70(5 Suppl):1414-24. Risk factors for high-dose cytarabine neurotoxicity: an analysis of a cancer and leukemia group B trial in patients with acute myeloid leukemia. J Clin Oncol. 1992 Jun; 10(6):948-53. Etoposide, doxorubicin, and cisplatin chemotherapy for advanced gastric adenocarcinoma: results of a phase II trial. J Clin Oncol. 1992 Apr; 10(4):536-40. Intensive post-remission therapy with Ara-C in adults with acute myeloid leukemia: initial results of a CALGB phase III trial. The Cancer and Leukemia Group B. Leukemia. 1992; 6 Suppl 2:66-7. Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum. J Clin Oncol. 1992; 10:549-557. Preservation of sphincter function in rectal carcinoma by a multimodality treatment approach. Surg Clin N Am. 1992; 1:137-145. Fluorouracil and high-dose leucovorin in previously untreated patients with advanced adenocarcinoma of the pancreas: results of a phase II trial. J Clin Oncol. 1991 Dec; 9(12):2128-33. Systemic therapy for colorectal cancer: an overview. Semin Oncol. 1991 Oct; 18(5 Suppl 7):62-6. A prospective evaluation of hepatic resection for colorectal carcinoma metastases to the liver: Gastrointestinal Tumor Study Group Protocol 6584. J Clin Oncol. 1991 Jul; 9(7):1105-12. Training in medical oncology: regaining the luster. J Natl Cancer Inst. 1991 Jun 19; 83(12):806-7. A pilot study of sphincter-sparing management of adenocarcinoma of the rectum. Arch Surg. 1991 Jun; 126(6):696-701; discussion 701-2. Prognostic value of lymphocyte surface markers in acute myeloid leukemia. Blood. 1991 May 15; 77(10):2242-50. Phase III trial of brief intensive treatment of adult acute lymphocytic leukemia comparing daunorubicin and mitoxantrone: a CALGB Study. Leukemia. 1991 May; 5(5):425-31. Prophylaxis of bacterial infections with ciprofloxacin in patients undergoing bone marrow transplantation. Transplantation. 1991 Mar; 51(3):630-6. Simultaneous administration of granulocyte-macrophage colony-stimulating factor and cytosine arabinoside for the treatment of relapsed acute myeloid leukemia. Leukemia. 1991 Mar; 5(3):230-8. A phase I study of intermittent continuous infusion high dose cytosine arabinoside for acute leukemia. Leukemia. 1990 Dec; 4(12):843-7. The unique aspects of acute promyelocytic leukemia. J Clin Oncol. 1990 Nov; 8(11):1913-21. Treatment of relapsed and refractory acute myeloid leukemia with diaziquone and mitoxantrone: a CALGB phase I study. Am J Hematol. 1990 Oct; 35(2):80-3. Intensive chemotherapy versus allogeneic bone marrow transplantation in first-remission acute myeloid leukemia. Bone Marrow Transplant. 1990 Jul; 6 Suppl 1:48-51. Acute leukemias in adults: an overview of recent strategies. J Cancer Res Clin Oncol. 1990; 116(1):94-6. A prospective trial of rcombinant human interferon alpha 2b in previously untreated patients with hepatocellular carcinoma. Cancer. 1990; 66:135-139. Pregnancy and leukemia. Semin Oncol. 1989 Oct; 16(5):388-96. The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group. J Clin Oncol. 1989 Oct; 7(10):1419-26. Status of adjuvant therapy for colorectal cancer. J Natl Cancer Inst. 1989 Sep 20; 81(18):1359-64. Morphologic and cytochemical characteristics of acute promyelocytic leukemia. Am J Hematol. 1989 Apr; 30(4):221-7. The medical course of cancer patients with fever and neutropenia. Clinical identification of a low-risk subgroup at presentation. Arch Intern Med. 1988 Dec; 148(12):2561-8. Value of a routine follow-up endoscopy program for the detection of recurrent colorectal carcinoma. Am J Gastroenterol. 1988 Dec; 83(12):1355-60. Allogeneic transplantation versus intensive chemotherapy in first-remission acute leukemia: is there a "best choice"? J Clin Oncol. 1988 Oct; 6(10):1532-6. Prognostic factors for colon cancer. J Clin Oncol. 1988 Jun; 6(6):1066-7. Prolonged high dose ARA-C infusions in acute leukemia. Leukemia. 1988 May; 2(5):304-6. Primary gastrointestinal lymphoma. Semin Oncol. 1988 Apr; 15(2):154-69. How is cancer treatment chosen? N Engl J Med. 1988 Mar 10; 318(10):636-8. Complete remission in acute promyelocytic leukemia despite persistence of abnormal bone marrow promyelocytes during induction therapy: experience in 34 patients. Blood. 1988 Mar; 71(3):690-6. Triazinate and platinum efficacy in combination with 5-fluorouracil and doxorubicin: results of a three-arm randomized trial in metastatic gastric cancer. J Natl Cancer Inst. 1988; 80:1011-1015. Clinical suspicion of autopsy-proven thrombotic and tumor pulmonary embolism in cancer patients. Am Heart J. 1987 Dec; 114(6):1432-5. Current chemotherapeutic treatment approaches to the management of previously untreated adults with de novo acute myelogenous leukemia. Semin Oncol. 1987 Dec; 14(4):384-96. Combination chemotherapy with diaziquone and amsacrine in relapsed and refractory acute nonlymphocytic leukemia: a Cancer and Leukemia Group B Study. Cancer Treat Rep. 1987 Sep; 71(9):879-80. Intensive postremission therapy in adults with acute nonlymphocytic leukemia using various dose schedules of ara-C: a progress report from the CALGB. Cancer and Leukemia Group B. Semin Oncol. 1987 Jun; 14(2 Suppl 1):25-31. Comparison of unique leucovorin and 5-fluorouracil "escalating" and "maximum" dosage strategies. NCI Monogr. 1987; (5):179-84. Phase II trials of the simple agents Baker's antifol, diaziquone, and epirubicin in advanced pancreatic cancer. Cancer Treat ep. 1987; 71:865-867. Therapeutic strategies in acute myelocytic leukemia: a status report of the experience of CALGB. Cancer and Leukemia Group B. Haematol Blood Transfus. 1987; 30:31-4. Is heparin administration necessary during induction chemotherapy for patients with acute promyelocytic leukemia? Blood. 1987 Jan; 69(1):187-91. Use of surface marker analysis to predict outcome of adult acute myeloblastic leukemia. Blood. 1986 Dec; 68(6):1232-41. Survival after postoperative combination treatment of rectal cancer. N Engl J Med. 1986 11 13; 315(20):1294-5. Fludarabine phosphate (NSC 312878) infusions for the treatment of acute leukemia: phase I and neuropathological study. Cancer Res. 1986 Nov; 46(11):5953-8. Adjuvant therapy in rectal cancer: a protocol proposal. Semin Oncol. 1985 Sep; 12(3 Suppl 4):116-20. Amsacrine in refractory acute leukemia. Cancer Treat Rep. 1985 Jul-Aug; 69(7-8):787-9. Intensive postremission therapy in adults with acute nonlymphocytic leukemia with ara-C by continuous infusion or bolus administration: preliminary results of a CALGB phase I study. Semin Oncol. 1985 Jun; 12(2 Suppl 3):84-90. Acute lymphoblastic leukemia in adults. Ann Intern Med. 1984 Oct; 101(4):552-4. B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation. J Clin Invest. 1984 Aug; 74(2):332-40. Patterns of failure after surgical cure of large liver tumors. A change in the proximate cause of death and a need for effective systemic adjuvant therapy. Am J Surg. 1984 Apr; 147(4):554-9. Adjuvant therapy for colon cancer: Results of a prospectively randomized trial. N Engl J Med. 1984; 310:737-743. Phase II study of methyl-CCNU, vincristine, 5-fluorouracil and streptozotocin in advanced colorectal cancer. J Clin Oncol. 1984; 2:770-773. Immunological and cytogenetic studies in two cases of B-cell acute lymphoblastic leukemia (Burkitt's type). Cancer Genet Cytogenet. 1983 Oct; 10(2):167-75. Doxorubicin in pregnancy: possible transplacental passage. Cancer Treat Rep. 1983 Sep; 67(9):773-7. Surface marker analysis of acute myeloblastic leukemia: identification of differentiation-associated phenotypes. Blood. 1983 Sep; 62(3):557-63. Chemotherapy for acute myelogenous leukemia in children and adults: VAPA update. Blood. 1983 Aug; 62(2):315-9. Long-term hepatic arterial infusion of 5-fluorodeoxyuridine for liver metastases using an implantable infusion pump. J Clin Oncol. 1983 May; 1(5):337-44. Acute leukemia after radiotherapy in a patient with Turcot's syndrome. Impaired colony formation in skin fibroblast cultures after irradiation. Am J Med. 1983 Feb; 74(2):343-8. The treatment of acute myelogenous leukemia in children and adults: VAPA update. Haematol Blood Transfus. 1983; 28:41-5. Factors influencing survival in patients with hepatic metastases from adenocarcinoma of the colon or rectum. Dis Colon Rectum. 1982 Nov-Dec; 25(8):749-54. The role of intensive postinduction chemotherapy in the management of patients with acute myelogenous leukemia. Cancer Treat Rep. 1982 Jul; 66(7):1455-62. More than MOPP for advanced Hodgkin's disease? N Engl J Med. 1982 Apr 01; 306(13):800-2. Heterogenous response to X-ray and UV light irradiation of cultured skin fibroblasts in two families with Gardner's syndrome. J Natl Cancer Inst. 1982; 68:697-701. A comparison of combination chemotherapy and combined modality therapy for locally advanced gastric carcinoma. Cancer. 1982; 49:1771-1777. Correlation of Plasma CEA and CEA tissue staining in poorly differentiated colorectal cancer. Am J Med. 1981 Aug; 71(2):246-53. Phase I--II trial of methyl-GAG in the treatment of patients with metastatic renal adenocarcinoma. Cancer Treat Rep. 1981 Jan-Feb; 65(1-2):17-20. VAPA10: a treatment program for acute myelocytic leukemia. Haematol Blood Transfus. 1981; 26:45-52. The use of preoperative plasma CEA levels for the Stratification of patients after curative resection of colorectal cancers. Ann Surg. 1980 Dec; 192(6):747-51. Increased gastrointestinal absorption of large molecules in patients after 5-fluorouracil therapy for metastatic colon carcinoma. Cancer Res. 1980 Oct; 40(10):3430-6. Treatment of acute myelogenous leukemia in children and adults. N Engl J Med. 1980 Aug 28; 303(9):473-8. Results of CEA-initiated second-look surgery for recurrent colorectal cancer. Am J Surg. 1980 Apr; 139(4):544-8. High dose methotrexate with leucovorin rescue. Rationale and spectrum of antitumor activity. Am J Med. 1980 Mar; 68(3):370-6. Testicular self-examination. N Engl J Med. 1980 Jan 31; 302(5):297. Phase I trial of bruceantin. Cancer Treat Rep. 1979 Nov-Dec; 63(11-12):1929-32. Microangiopathic hemolytic anemia and cancer: a review. Medicine (Baltimore). 1979 Sep; 58(5):377-84. The rate of postoperative CEA rise in selecting treatment for recurrent colorectal cancer. Gastroenterology. 1979; 76:1223. Carcinoembryonic antigen (CEA) as a monitor of chemotherapy in disseminated colorectal cancer. Cancer. 1978 Sep; 42(3 Suppl):1428-33. Transient carcinoembryonic antigen (CEA) elevations following resection of colorectal cancer: a limitation in the use of serial CEA levels as an indicator for second-look surgery. J Natl Cancer Inst. 1978 Aug; 61(2):315-8. 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Relationships between components in primate RNA tumor viruses and in the cytoplasm of human leukemic cells: implications to leukemogenesis. Cold Spring Harb Symp Quant Biol. 1975; 39 Pt 2:933-61. Reverse transcriptase in normal rhesus monkey placenta. Science. 1974 Sep 06; 185(4154):864-7. Cardiac ultrastructural changes induced by daunorubicin therapy. Cancer. 1973 Oct; 32(4):771-88. Dreaming and Korsakoff's psychosis. Arch Gen Psychiatry. 1968; 18:203-209. Research Departments: Medical Oncology/Solid Tumor Oncology Dana 1602 Dana-Farber researchers present findings in more than 70 research studies at ASCO annual meeting 2019 Dana-Farber Cancer Institute faculty recognized as 2019 ASCO leaders in cancer care New drug combination extends survival of patients with metastatic colorectal cancer
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Q: Central area of Images Unclickable If one visits http://www.viking.ee/en/windows/tripleglazing/ - where the central play/pause button is unclickable or visits the gallery on the same page, where the images inside the gallery are unclickable there is a general problem with image links not working. I did not build the theme that the site is based on originally (it was bought from an Indonesian online, no kidding, and configured later on) and could not find out what part of the configuration caused the problem. Could anyone help with taking a look with Firebug or other Inspect Element tools to see what is causing the problem. There is no need to actually propose a solution. It´s just the problem definition I am after. A: There's a ul tag that causes the problem. After removing it, the button is clickable and works properly. The ul tag I'm talking about starts in the 118th line of code and ends in the 125th. It looks like this: <ul class="toimiv"> <li class="prev"> <a href="#">Next</a> </li> <li class="next"> <a href="#">Prev</a> </li> </ul> A: It's the slideshow controls that cause the problem, they are displayed over the play button thus making the clicks not register on the playbutton but on the container of the controls. You can either position the controls a little higher or lower by changing the top css value for the ul.toimiv element or you could position the next and previous buttons using relative positioning and the left or right css properties.
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Contributing ============ Issues ------ Feel free to [open an issue](https://github.com/amercier/npm-package-skeleton/issues/new), or propose a [pull request](https://github.com/amercier/npm-package-skeleton/pulls). To prevent duplication, please look at [existing issues](https://github.com/amercier/npm-package-skeleton/issues?q=is%3Aissue) before posting a new one. TL;DR ----- | Command | Description | |-----------------|-------------| | `npm test` | Runs test suite once using Mocha. Generates code coverage report in the `coverage` directory (run `open coverage/index.html` to view full HTML report). | | `npm start` | Runs test once, watch for changes in dev/test files, then re-runs tests automatically when a file changes. <br><small>_**Note:** as opposed as `npm test`, it doesn't generate a code coverage report._</small> | | `npm run lint` | Runs ESLint linter. <br><small>_**Note:** this is automatically run before the test suite by `npm test`, but not by `npm start`_.</small> | | `npm run doc` | Generates API documentation in `esdoc` folder. <br><small>_**Note:** this is not expected to be run manually since ESDoc hosting service runs it for you._</small> | | `npm transpile` | Transpile all files from `src` directory to `dist`, using Babel. <br><small>_**Note:** this is not expected to be run manually since it is automatically run before NPM packaging (`package.json`'s `prepublish` script)._</small> | Getting started --------------- #### Step 1. Checkout repository _**Prerequisites:** you need to have `git`, `node` (>=0.10) and `npm` installed_. ```bash git clone https://github.com/amercier/npm-package-skeleton.git ``` _(or your clone's Git URL)_ #### Step 2. Install NPM dependencies ```bash npm install ``` #### Step 3. Run tests (run-once mode) ```bash npm test ``` ```log > [email protected] test /.../npm-package-skeleton > npm run lint && rm -rf coverage && istanbul cover _mocha -- specs --recursive --compilers js:babel-register > [email protected] lint /.../npm-package-skeleton > eslint . myModule ✓ exists ✓ is true 2 passing (21ms) ----------|----------|----------|----------|----------|----------------| File | % Stmts | % Branch | % Funcs | % Lines |Uncovered Lines | ----------|----------|----------|----------|----------|----------------| All files | 100 | 100 | 100 | 100 | | index.js | 100 | 100 | 100 | 100 | | ----------|----------|----------|----------|----------|----------------| ``` #### Step 4. Run tests (TDD mode) ```bash npm start ``` Coding standards ---------------- This project follows [Airbnb Javascript Style Guide](https://github.com/airbnb/javascript). It is enforced at build time by [ESLint](http://eslint.org/). License ------- ISC © Alex Mercier (see [LICENSE.md](LICENSE.md)).
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Healthcare- where is the Government's role? The Taiwanese Minister of Health has criticized the Singapore's system as one that the government has shirked off their social responsibility towards the citizens in terms of providing basic health care. Incidentally, I have been studying the Taiwanese Medical Insurance system which has provided a Universal coverage for ALL its citizens as well as foreign workers. I have put up my proposal to NSP manifesto committee on revamping the Medishield system. The basic idea of this new Medical Insurance scheme is to have the government and employers to share part of the premiums paid as Medishield for their Singaporean workers. Read more at Goh Meng Seng's blog: Singapore Alternatives.
{'redpajama_set_name': 'RedPajamaC4'}
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Posted on March 22, 2018 at 12:17 pm. Dinwiddie County, VA – Governor Ralph Northam today announced that Richlands Creamery, LLC will create 17 new jobs and invest $1,700,000 in Dinwiddie County to create a new commercial creamery. As part of this project, Richlands Creamery, LLC commits to purchasing over $959,071, 100% of its agricultural inputs from Virginia farmers. The Tobacco Region Revitalization Commission approved a $40,000 Tobacco Region Opportunity Fund grant to assist with this project. Posted on March 22, 2018 at 10:02 am. Richmond, VA – Governor Ralph Northam announced today that KMR Aviation Services Inc. will expand in Bedford County. KMR will invest $1 million to purchase a 7,200 square foot facility they currently lease and add a new repair facility. The project will create 12 new jobs. The Tobacco Region Revitalization Commission is supporting this project with a $35,000 Tobacco Region Opportunity Fund grant. Posted on March 12, 2018 at 4:42 pm. Richmond, VA – The Virginia Tobacco Region Revitalization Commission met on Thursday, March 8th to review proposals to extend broadband service. The Commission approved 9 funding requests for broadband expansion projects in Southern and Southwest Virginia, totaling more than $11 million in new spending. The projects approved at this meeting will result in broadband becoming available for more than 31,000 homes and businesses and Tobacco Commission investment will be matched by more than $16 million in additional funds. Posted on March 8, 2018 at 4:02 pm. Lee County, VA – Governor Ralph Northam announced today that England Furniture will establish a manufacturing operation in Lee County. The facility will be located at the Lee County Industrial Building and will cover 32,000 square feet. This project will create 79 new jobs. The Tobacco Region Revitalization Commission approved a $135,000 Tobacco Region Opportunity Fund grant for this project. Posted on March 7, 2018 at 9:49 am. Pittsylvania County, VA – Governor Ralph Northam announced today that Panaceutics will establish a pharmaceutical manufacturing operation in Pittsylvania County. The project will create 70 new jobs and result in $5.8 million in capital investment. The facility will be located at the Cane Creek Centre Industrial Park. The Tobacco Region Revitalization Commission approved a $405,000 Tobacco Region Opportunity Fund grant for this project. Posted on February 27, 2018 at 4:43 pm. Richmond, VA – Governor Ralph Northam announced today that Innovairre Communications, LLC will expand their operation in Bedford County. The expansion will create 12 new jobs and 72 existing employees will be retrained to utilize the new digital printing technology Innovairre will use to produce direct mail fundraising materials for the nonprofit sector. The expansion will also result in $4.85 million in capital investment for the new printing equipment. Posted on February 20, 2018 at 2:21 pm. Richmond, VA – ValleyStar Credit Union will invest $5.25 million to build a new administrative campus in Franklin County. The project will result in 10 new, high-paying, jobs with 32 total employees working at the new facility. ValleyStar will be the first business to locate at Summit View Business Park. The Tobacco Region Revitalization Commission awarded a $40,000 Tobacco Region Opportunity Fund grant to assist with this project. Posted on February 16, 2018 at 9:36 am. Richmond, VA – Governor Ralph Northam announced today that Eastern Panel Manufacturing Inc. (EPM) will expand its operation in Pittsylvania county. As part of the expansion, the company will move to a 55,000 square foot facility in the Chatham Industrial Park. The expansion will create 15 new jobs and includes $1 million in capital investment. The Tobacco Region Revitalization Commission awarded a $30,000 Tobacco Region Opportunity Fund grant to assist with this project. Posted on January 11, 2018 at 4:54 pm. Pittsylvania County, VA – Governor Terry McAuliffe announced today that Amthor International will expand their tanker truck manufacturing operation in Pittsylvania County. The expansion includes the construction of a new 115,000 square foot production and will create 70 new jobs over 3 years and 90 new jobs over the next 5 years. The expansion will also result in $7.1 million in capital investment. Posted on January 11, 2018 at 1:01 pm. Martinsville, VA – It was announced today that Stateline Heart & Vascular will open a new office facility to expand their current operations. This expansion will result in the creation of 10 new high paying jobs. The Tobacco Region Revitalization Commission is supporting this project with a $120,000 Tobacco Region Opportunity Fund grant.
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because she looked like Joni Mitchell. over the new Steely Dan album. I don't blame him. to build a bridge from Kokomo to San Francisco that's still burning. that ghosts exist. They come back for birthdays and Christmas.
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Q: Creating oposite Mirror picture by manipulate Kinect Color pixels I am trying to create an opposite mirror picture from the color stream, i.e., when right hand is moving up, I want that kinect will draw the left had to move up (unlike in-front of real mirror that the right hand is raising )i want to manipulate the color image to do that: just moving the X position. However, I get a blue screen : void kinectSensor_ColorFrameReady(object sender, ColorImageFrameReadyEventArgs e) { try { using (ColorImageFrame colorImageFrame = e.OpenColorImageFrame()) { if (colorImageFrame != null) { byte[] pixelsFromFrame = new byte[colorImageFrame.PixelDataLength]; colorImageFrame.CopyPixelDataTo(pixelsFromFrame); Color[] color = new Color[colorImageFrame.Height * colorImageFrame.Width]; kinectRGBVideo = new Texture2D(graphics.GraphicsDevice, colorImageFrame.Width, colorImageFrame.Height); // Go through each pixel and set the bytes correctly // Remember, each pixel got a Rad, Green and Blue int index = 0; for (int y = 0; y < colorImageFrame.Height; y++) { for (int x = 0; x < colorImageFrame.Width; x++, index += 4) { color[(y * colorImageFrame.Width + x)] = new Color(pixelsFromFrame[(y+1)*(2560 -index)], pixelsFromFrame[(y + 1) * (2560 - index)], pixelsFromFrame[(y + 1) * (2560 - index)]); } } // Set pixeldata from the ColorImageFrame to a Texture2D kinectRGBVideo.SetData(color); } } } catch { } } Can anyone tell me what is worng ? Thanks erez A: The code to create a reflection is unsafe void reflectImage(byte[] colorData, int width, int height) { fixed (byte* imageBase = colorData) { // Get the base position as an integer pointer int* imagePosition = (int*)imageBase; // repeat for each row for (int row = 0; row < height; row++) { // read from the left edge int* fromPos = imagePosition + (row * width); // write to the right edge int* toPos = fromPos + width - 1; while (fromPos < toPos) { *toPos = *fromPos; //copy the pixel fromPos++; // move towards the middle toPos--; // move back from the right edge } } } } This makes it so that the bytes in toPos and fromPos switch sides because the code fixes a byte pointer at the base of the image data bytes and then creates an integer pointer from that value. This means that to copy all the data bytes for a single pixel from one place to another, the program can use a single statement: *toPos = *fromPos; Source
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Malawi's most prestigious football team, Big Bullets have controversially inked a $900,000 (822,000 euros) sponsorship deal with a cigarette manufacturing company, attracting the wrath of a local rights group. The deal, with the country's sole cigarette manufacturer Nyasa Manufacturing Company (NMC), will be effective from January and the sponsorship money will be spread over five years. But local NGO, Drug Fight Malawi, has attacked the deal, saying this was a "deliberate and well-orchestrated strategy for the company to market its products and increase tobacco consumption among children." Bullets, twice champions of the country's Super League and who command the biggest fan base spread throughout the tiny and soccer-mad southern African nation, has been without sponsorship for nine years since former president Bakili Muluzi sponsored them for two years. "This is a strategic business partnership and uses the team's supporters' base to enhance their brand," Sam Chilunga, who chairs the 1967-founded team, told AFP. NMC finance chief Fleet Haiya told reporters that the team "will boost our brand since the number of supporters is overwhelming." But Drug Fight Malawi's executive director Nelson Zakeyo said in a statement the deal was "in sharp contradiction to the healthy lifestyle of sports as espoused by FIFA." He said in Malawi, one of the largest growers of tobacco which wires in 60 percent of foreign exchange, more than 26 percent of men and seven percent of youths smoke tobacco. "Tobacco is one of the greatest public health challenges facing the world today," Zakeyo added. The group wants FIFA to "reaffirm its commitment to keeping football tobacco free by publicly opposing the Big Bullets tobacco company sponsorship deal and work with the team to find alternative source of funding." However, the deal has the blessings of the Football Association of Malawi (FAM). "There is nothing wrong with the deal. FIFA and FAM are happy that a big team has secured a huge sponsorship," FAM's president Walter Nyamilandu said. Nyamilandu says the deal has also been approved by world football's governing body: "FIFA gave us a go ahead," he said. While FIFA does not promote tobacco products at events it organises, it has no jurisdiction over the right of individual teams or even national federations to sign sponsorship or marketing deals with whomsoeever they choose. Most of the 16 teams in Malawi's poorly-run amateur super league are sponsored by the Army, Police and government. The rest are owned by private clubs.
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Notes from Ann: Don Hall In today's post, Ann Patchett remembers Donald Hall, the memoirist, essayist, and former US Poet Laureate. His work was honored more times and in more ways than we have room to list here, including the Ruth Lilly Poetry Prize for lifetime achievement, the Robert Frost Medal from the Poetry Society of America, the LL WInship/PEN New England Award, the National Book Critics Circle Award for Poetry, the Caldecott Medal, and the National Medal of Arts — plus several nominations for the National Book Award. Hall passed away at home in New Hampshire on June 23, 2018. In 1985, when I was a graduate student at the Iowa Writers' Workshop, my best friend Lucy and I would become obsessed by what we read. We belted out Roethke's "My Papa's Waltz" for a full semester. We tried to memorize the first chapter of García Marquez's One Hundred Years of Solitude. We fell in love with many short stories. I was there to learn how to write short stories so there was a whole raft of them I obsessed over, but none were as close to me as "The Ideal Bakery" by Donald Hall. Hall was a famous poet, and so he had a knack for condensing the turning points of life into a few words. This short story was short, yet it seemed to contain the entirety of life itself. The book, a collection of stories also called The Ideal Bakery, later went out of print. I kept my battered paperback close at hand and read it again and again. I think the DNA of that story could probably be found in everything I've written since. Fast forward to December of 2014, the month Donald Hall published a slim book called Essays After Eighty. It was the cover that got me, a close-up photo of Hall's face, bearded and wild and very much after 80. (This is why we need real bookstores, because you walk past a book and see a man's face on the cover and think, That book. Yes.) In the first essay, called "Out the Window," he writes, "After a life of loving the old, by natural law I turned old myself. Decades followed each other — thirty was terrifying, forty I never noticed because I was drunk, fifty was the best with a total change of life, sixty began to extend the bliss of fifty – and then came my cancers, Jane's death, and over the years I traveled to another universe. However alert we are, however much we think we know what will happen, antiquity remains an unknown, unanticipated galaxy. It is alien, and old people are a separate form of life." Every piece in Essays After Eighty blazed with insight and memory, loss and abundant life. Once again I went back to "The Ideal Bakery," and back to Hall's poems. Once again I was struck by his ability to get everything that mattered into a handful of words. A few days after I read the book, I was in New York to tape a television show. There was a big group of us sitting in theater seats awaiting instruction. The person in the seat next to me was Tom Brokaw. An admiral came over and told Mr. Brokaw he was sorry to hear about Brokaw's cancer. Tom Brokaw thanked the man and said he was doing OK. When the admiral left, Tom Brokaw turned and looked at me. We had not been introduced. "I'm sorry about the cancer," I said. Tom Brokaw told me he'd been reading a lot about death. I told him I owned a bookstore. All the books I could think to recommend he had already read, but then I remembered Essays After Eighty, which was as much about death as it was about everything else. It was brand new. Surely he hadn't read it yet. "Don Hall!" Tom Brokaw said. "He's my pen pal." In this television studio stuffed full of famous people, I was star-struck unto dizziness. "You get letters from Donald Hall?" Two years later, Don Hall emailed me. Parade magazine had asked the bookstore to pick our favorite 75 books in the last 75 years. I included The Collected Poems of Jane Kenyon, a wonderful writer who had died of leukemia at the age of 47. There were also a couple of the characters in my last novel, Commonwealth, who read Kenyon's poems. Jane had been Don's wife. He wrote to thank me for thinking of her. I wrote him right back and he wrote to me again: Dear Ann, I love it that you love Jane's poems and keep saying so in print! I didn't know you knew my name! Goodness knows your letter pleases me so much! I was thinking lately that nobody remembers that I used to write short stories – but now you speak of "The Ideal Bakery"! You do more than speak of it, I know, I know. And you liked my Essays After Eighty also. After that we struck up a small correspondence. He sent me a copy of Willow Temple, a collection of his stories where "The Ideal Bakery" had been reprinted. I sent him a copy of a Housman poem, "To an Athlete Dying Young" and we talked about Housman. He wrote: I had not read that Housman for so long! I had forgotten it was, for a Shropshire lad, so long. I'd also forgotten how beautifully he makes use of the headless line. I've always been a prosody nut, although I suppose most of my stuff is free verse. I started with meter in most of my first book, then dropped it, and returned — because of loving Thomas Hardy's poems — to meter and rhyme in later poems. I still cannot completely wrap my mind around this exchange — Don Hall and I emailing about poetry like it was the most natural thing in the world. He sent me the link to a piece he'd written for The New Yorker about Jane. We signed those emails with love and exclamation points. When I found an advanced reading copy of his new essay collection Carnival of Losses: Notes Nearing Ninety in the back room of Parnassus, I read it in a day. The essays are about Jane, about the house where his family lived in New Hampshire, the same house where he and Jane would later live together and where he then lived alone. It's a book about Jane and the long arm of grief. It's about the poets he knew. It's about a children's book he wrote called The Ox-Cart Man that wound up making such a difference in his life. But it's also more than any of that. The book is about who Don was and how he saw the world. I'm here to tell you there is nothing better. Every superfluous word is stripped away and what is left is the pure force of life. So here's what concerns me: that you might see a book called Essays After Eighty or Carnival of Losses: Notes Nearing Ninety, both with pictures of the same grizzled old man on the front cover, and think, That book is not for me. That doesn't apply to me. But it does. Don Hall holds up a lantern for the rest of us, shining the extraordinary light of his mind on what's ahead. I wrote to my hero and asked if I could blurb his magnificent new book. I couldn't decide if I was being admiring or horribly presumptuous. What does Don Hall need from me? I'm thrilled to read your email! It's the first Word I have received from the outside world, from the ARC! In 1959 I hated the blurbs I had written, so much that I decided never to do any more. Since then, I have refused 4,000 requests for blurbs – from total strangers, from good friends – so I can't accept your generous offer. If you see me quoted on a jacket, about a book, it had to be from a book review I did. I wrote him back and said that made perfect sense, but at 89 he was also free to change his policy. If he wanted the blurb, if his editor wanted it, it would be here waiting. His editor wrote to me the next day. I feel very grateful to have been given the chance to say publicly how much I loved Carnival of Losses and how much I loved Don. Of course, the thing that Donald Hall is famous for is poetry, and if you're looking for poetry then his Selected Poems is a great place to start. If you prefer a single, slim volume, I would steer you to Without. Or start anywhere you like. There are no bad choices. Inasmuch as my life briefly tapped against Don Hall's life, I brushed with greatness. I'm not talking about the emails, which were a ridiculous thrill. I'm talking about finding "The Ideal Bakery" when I was 21, and all the poems, the children's books and essays, and especially A Carnival of Losses. It's all right there, all the wonder of another person's life and talent and time, waiting in a book. It is a tremendous inheritance for all of us. Don died on June 23, 2018, three months shy of 90. A Carnival of Losses will be published on July 10. – Ann This post also runs today on Lit Hub. Posted in Ann's BlogTagged carnival of losses, donald hall, essays after eighty, notes nearing ninety Prev The Great Believers: An Excerpt from Rebecca Makkai's New Must-Read Novel Next Beach Bag Refill: 18 Books We Love Right Now
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Commentareum A place of culture, politics, and discourse. Guest Posting Policy About Feature Images State of the Discussion (beta) The 500kth Ordinary Comment Conservative Pathways Misfits Politics American Creation Paradox Project Blinded Trials Mindless Diversions Bookclubs! Not a Potted Plant Journeys in Alterity Safe Depository Daily Archive: November 19, 2012 Mike Dwyer /// November 19, 2012 Walking Dead Discussion Thread: S3 E6, "Hounded" *Spoiler Alert: Do not read this post or the comment section if you have not seen the show. Also, for those who have read the comics, please do not discuss plot elements not revealed on the... Jason Kuznicki Comment Rescue: Once More, with Feeling Brian Houser writes: "But how can a libertarian believe that any system that transfers wealth by supporting social safety nets, public school funding, or progressive taxation is just?" Ultimately, he can't (unless all that... Meditating on Hipsters, Irony, and the Role of Status What follows is in reference to this post about hipsters and irony. I will attempt to demonstrate one theory for how we get from hipsterism on the one hand to the politically destructive use of irony on the other.... J.L. Wall My Handwriting, My Self New languages seep into you—slowly at first, and then, suddenly, you begin to notice its influence. At least in the anecdotes, this frequently happens through the confusion of words as the mind is momentarily... Forward Movement for the GOP Senator Rand Paul, Kentucky's junior senator, was not my first choice when he ran for his seat in 2010. The Tea Party scared the hell out of me and I wanted a more moderate candidate.... Treme, Season 3, Episode 9, "Poor Man's Paradise" I've argued through my recaps this season that we're seeing a very defined cleavage between the behavior of the show's white characters and the behavior of the show's non-white characters. I have spent the... Manifestly American: FIFA Women's World Cup Champions Elections In The Meantime Ten Second News Biden Sings Same Song, Second Verse [caption id="attachment_316702" align="aligncenter" width="750"] Photo by Pete Souza Public domain [/caption] Meanwhile, in non President Trump vs "The Squad" news, current Democratic primary frontrunner Joe Biden was unveiling his healthcare proposal, and the tagline he laid on the folks at an AARP gathering sounds strangely familiar. Former Vice President Joe Biden on Monday said that under his new health care plan, people who like their insurance coverage won't be forced to give it up. Speaking at the AARP presidential forum in Iowa, Biden drew a contrast between his plan, which would give people a Medicare-like public option, and the "Medicare for All" plan championed by more progressive Democratic presidential candidates including Sens. Bernie Sanders (I-Vt.) and Elizabeth Warren (Mass.). "If you like your health care plan, your employer based plan, you can keep it. If in fact you have private insurance, you can keep it," Biden said. Biden's speech echoed the now-infamous "if you like your doctor, you're going to be able to keep your doctor" catchphrase former President Barack Obama repeatedly said in 2009 and 2010 when he was trying to sell the public on the benefits of the Affordable Care Act. The GOP seized on those remarks, and spent years throwing them back at Democrats to showcase what they said were ObamaCare's failures. In 2013, PolitiFact called "if you like your health care plan, you can keep it" the "Lie of the Year." But the law has provided 20 million people with health insurance, and it's now more popular than ever. Biden is running on protecting ObamaCare. He is banking the law's popularity will convince voters that his plan of shoring up the law with more subsidies and a public option is a better approach than Medicare for All. "You get your choice, you get full coverage … I think it's the quickest, most reasonable rational and best way to get to universal coverage," he said. In formally announcing his plan on Monday, Biden equated the push for Medicare for All with the GOP attempts to repeal ObamaCare. "I understand the appeal of Medicare for All, but folks supporting it should be clear that it means getting rid of ObamaCare, and I'm not for that," Biden said in a video announcing his plan. Labor Secretary Alexander Acosta Resigns Amid Epstein Furor [caption id="attachment_316589" align="aligncenter" width="739"] photo by Gage Skidmore via Wikimedia Commons[/caption] The head many have been calling for since the details of Jeffrey Epstein's plea deal were first reported has finally rolled: President Donald Trump alerted reporters this morning of Acosta's departure. "This was him, not me," said Trump as Acosta stood beside him. Trump, who saw Acosta largely as a source of favorable monthly statistics about unemployment and job growth, called Acosta "a great labor secretary not a good one" and "a tremendous talent. He's a Hispanic man, he went to Harvard, a great student." Trump indicated that he was satisfied with Acosta's explanation for the plea deal in Wednesday's news conference, saying, "He explained it." But Acosta has had a rocky relationship in recent months with other White House officials, including acting chief of staff Mick Mulvaney, over the perceived slow pace of deregulation at the department. And one person familiar with the situation said that although Trump initially thought Acosta handled the Epstein controversy well, over the last couple of days the president saw the negative press and didn't like it. "POTUS is not a fan of bad press, especially when other people make him look bad," this person said. Acosta, a 50-year-old Harvard-educated lawyer, came newly under fire for the lenient 2008 plea deal after Epstein was re-arrested July 6 in New York City and charged with sex trafficking. Under the earlier plea agreement, Epstein served only 13 months of an 18-month term and was permitted daily furloughs to go to the office. Epstein also was required to register as a sex offender and to pay restitution to his underage victims. At the White House this morning, Acosta told reporters: "Over the last week I've seen a lot of coverage of the department of labor. And what I have not seen is the incredible job creation that we've seen in this economy. more than 5 million jobs, I haven't seen that.... I do not think it is right and fair for this administration's labor department to have Epstein as the focus, rather than the incredible economy that we have today." Cuff the Midwife A horrible story raises age-old questions about regulation, medical care, and people who make money insisting they know better than trained professionals. At about 9:15 p.m. June 15, Omaha Fire Department paramedics were called to a home where a 25-year-old woman at full term in her pregnancy was in distress following complications during a breech birth. The woman told police she went into labor at about 9 p.m. June 14. Hock reportedly arrived to help with the birth at 6 p.m. June 15, according to a criminal complaint. After realizing the baby's foot had been delivered, the mother told detectives that Hock asked her whether to continue with the birth at home "and stated she had trained in delivering breech babies," court documents state. The mother agreed to continue at home but said that after at least 30 minutes, the baby had only been delivered up to the shoulders, the documents state. That's when Hock advised calling 911. When police arrived, they found Hock assisting the pregnant woman and asking for medical scissors, court documents state. Paramedics said the baby was partially delivered at that time and that Hock performed a medical procedure during her attempt to deliver the baby. The baby, delivered by paramedics while en route to a hospital, was limp and unresponsive, according to the criminal complaint. Resuscitation attempts were unsuccessful. The baby was taken to the Newborn Intensive Care Unit upon arrival at the hospital and placed on life support, the documents state. The obstetrics doctor in the ER that night reported to police that the baby was deprived of oxygen and suffered swelling in the brain and indicated the infant could die as a result of the injuries. The doctor told officers Hock had revealed she was at the scene serving as a midwife, a service she advertises through her company's website, Nebraska Birth Keeper, and "had known for a couple hours that the baby was in breech" position but continued with the birthing process for an hour before 911 was called, the court documents state. The baby was pronounced dead June 17. A warrant was issued for Hock's arrest when it was determined by Nebraska Health and Human Services that she does not hold a medical or certified nurse-midwife license. The mother told investigators she had signed an agreement for Hock's midwife services and that she and her husband had paid Hock about $3,000 to $4,000 for those services. Home births are illegal in Nebraska. This was the second time the Noes had used Ms. Hock in the birthing of a child. That pregnancy as well resulted in a breech birth, and the Noe's opted for the hospital and a C-Section delivery. The couple paid about $4,000 for Ms. Hock's services, according to Mr. Dornan, who said Ms. Hock served as a midwife when Ms. Noe gave birth to another child two years earlier. "They wanted to have a birth in their bedroom," Mr. Dornan said. "Didn't want to go to the hospital." Similar complications arose during the earlier pregnancy with a breech baby, he said, and Ms. Noe opted to have a C-section at the hospital after Ms Hock advised her of the risks. This time, he said, Ms. Hock once again warned Ms. Noe of the risks of a breech birth, but that she had opted to remain at home. Mr. Dornan said Ms. Hock tried a maneuver to dislodge the baby, but was unsuccessful. She was accompanied by her 9-year-old daughter and a doula, who Mr. Dornan said called 911. When the emergency responders arrived at the home, Mr. Dornan said, they gave Ms. Hock a pair of scissors to try to help make a wider opening for the baby, which is considered to be a surgical procedure and is mentioned in the criminal complaint against his client. Trump Meets Kim, Steps in North Korea President Donald Trump went there: On Sunday, Mr Trump became the first sitting US president to set foot in North Korea, accompanied by leader Kim Jong-un. Mr Trump had earlier tweeted asking Mr Kim if he would like to meet while the US president was in South Korea. On Monday, KCNA carried extensive coverage of the unprecedented meeting. North Koreans rarely receive news of the outside world, and the heavily controlled media has depicted the US as its most hated enemy for decades. Images of the US president walking into the North as a friend of Mr Kim will be an extraordinary sight for ordinary North Koreans. Negotiations over North Korea's controversial nuclear programme have stalled since the second summit between the two leaders ended without an agreement in February. After their surprise talks on Sunday, they reaffirmed their claims to friendship and said talks would continue through their negotiating teams. Critics have dismissed the occasion as an act of political theatre which does not make substantial progress towards North Korea giving up its nuclear weapons. Negotiations with North Korea to try to convince it to abandon its controversial nuclear programme reached a peak last year when Mr Trump and Mr Kim had a historic meeting in Singapore. They both committed to the "complete denuclearisation" of the Korean peninsula, but without clarifying what that meant. It was hoped their second meeting, in Hanoi in February, would make some concrete agreement about North Korea handing over its nuclear programme in exchange for some of the tight sanctions against it being lifted. But those talks ended with no deal, as they failed to agree on the pace at which sanctions should be eased. SCOTUS: "partisan gerrymandering claims are not justiciable" Whoa...people can over-react to Supreme Court rulings, but this ruling, and the reaction, is going to be big. In a 5-4 decision along traditional conservative-liberal ideological lines, the Supreme Court rules that partisan redistricting is a political question, not reviewable by federal courts and can't judge if extreme gerrymandering violates the constitution. "We conclude that partisan gerrymandering claims present political questions beyond the reach of the federal courts," Chief Justice Roberts wrote for the conservative majority. "Federal judges have no license to reallocate political power between the two major political parties, with no plausible grant of authority in the Constitution, and no legal standards to limit and direct their decisions." The court's ruling came in two cases. In Maryland, Democrats who controlled the state legislature drew new lines for congressional districts to eliminate one of the state's two GOP seats in the U.S. House of Representatives; and in North Carolina, where Republicans controlled the state legislature, they used the same tactics to isolate and limit Democratic power, and maximize their own. Lots more to come from this... Read the full opinion here. Daniel Bergstresser // 3 Comments How Protests Happen, What They Do Will Truman // 280 Comments Bigot. 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Starting The Day Off With Flies Sunday Morning! Wrapping up Stranger Things 3 The Days of Real Sport: I Never Astum! Democratic Presidential Candidates: To Whom Should We Extend Your Compassion? Paying the Price of Admission A Camp By Any Other Name Would Smell as Foul Un-Ravelry The End of the Citizenship Fight Debatable: The Slog in South Beach Part 2 Socialized Healthcare and Paternalism Mike Schilling says: You know, I didn't remember that. The landing on the... Mike Dwyer says: So, white liberals are immune to the blame for bad policy... For octonions, the analogy is a Lie algebra. ... Chip Daniels says: "At a Border Patrol holding facility in El Paso, Texas, an... greginak says: Sorry mike, you may not like D policies and in some... Yeah bad policy hurts. I'm all about talkign policy. Guy who... Chip - see my reply to Greg about busing. I see... Okay - so someone that is politically engaged enough to even... What I discovered when I became a liberal is that when... Dark Matter says: You are doing very impressive mental backflips to justify not voting... Featured Comment To Mike Dwyer Chip Daniels in reply to Mike Dwyer I'm not here to convert anyone. I'm not trying to be the pickup artist of politics, to slyly get Trumpists to vote Democrat even if they hate themselves in the morning. The most persuasive argument is always to just speak the truth. If people reject that, they were never "gettable" to begin [...] Mike Schilling in reply to Oscar Gordon on Tech Tuesday – Spooky Action EditionYou know, I didn't remember that. The landing on t… Mike Dwyer in reply to greginak on Bigot.So, white liberals are immune to the blame for bad… Mike Schilling in reply to veronica d on Tech Tuesday – Spooky Action EditionFor octonions, the analogy is a Lie algebra. Yeah,… Chip Daniels in reply to Dark Matter on Bigot."At a Border Patrol holding facility in El Paso, T… greginak in reply to Mike Dwyer on Bigot.Sorry mike, you may not like D policies and in som… greginak in reply to Mike Dwyer on Bigot.Yeah bad policy hurts. I'm all about talkign polic… Mike Dwyer in reply to Chip Daniels on Bigot.Chip - see my reply to Greg about busing. I see th… Mike Dwyer in reply to greginak on Bigot.Okay - so someone that is politically engaged enou… By Sana Ali By Luis A Mendez Ronald Reagan's Missing Overcoat By Dennis Sanders Oh Say, I Could See By Starla Jackson The Democratic Candidates: Em's Perspective By Em Carpenter Ordinary Twitter Tweets by Ordinarians Ordinary Times © 2019. All Rights Reserved.
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The map displays the most recent cases. Nation-wide cases are displayed next to the country name. The database is updated daily and grows at a rate of approximately 20-30 new entries a week. To date, more than 22,000 restructuring events have been recorded. In order to be included in the database, an individual case of restructuring must involve the announced loss or creation of at least 100 jobs, or employment effects affecting at least 10% of a workforce of more than 250 people. A restructuring statistics tool is available to explore summary data from the restructuring events database by country, sector and restructuring type.
{'redpajama_set_name': 'RedPajamaC4'}
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About the CBS Support the CBS #knoydartknowledge Progress Updates Community Share Offer The Old Forge Community Benefit Society Progress update 27.03.21 A wee progress update. March has been a busy month behind the scenes, and we wanted to keep folk up-to-date on where we are. We instructed a valuer and structural surveyor who have viewed the property. This information will feed in to finalising our funding target and aspects of the business plan. We are working with a team of consultants from Skye to create a business plan. This document will be required for any future grant applications or share offers, and will set out a viable business model to follow should the community bid be successful. Our consultants are conducting desk-based research at the moment and we hope to have them over for a visit and to view the pub around May. We are still in discussions with Community Shares Scotland to finalise the best model CBS rules to register the group formally. We have to take in to account the eligibility requirements for any future grant applications (ie. the second stage Scottish Land Fund which we have been invited to apply for) and ensure that our constitution is set up in a way that is suitable. This has taken a lot of zoom calls and discussions, but we're getting there and hope to have a final decision made imminently. In line with the CBS set up, we are also looking at the various funding options available to us to work out what combination will work best. If you have any questions, comments or ideas at any time please get in touch! Pop a message to our social media pages or email [email protected] Photo (c) Mark Harris. Job Opportunity - Project Manager Crowdfund Complete! © The Old Forge Community Benefit Society Ltd, Knoydart, Scotland.
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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So much POOP. What about Fleas? Diatomaceous earth. Part One. Poop is disgusting. No one wants to mess with poop. But poop can be a great indicator of our and our animals health. So checking poop is a necessary part of animal husbandry. Ick. Initially I was going to post photos of the poop we daily encounter. But, the stark reality of poop pictures might prove to be too much for sensitive types. I've been scolded for posting photo's of what some consider gruesome subjects : like Lance's finger when he sliced the tip off, and Lance's finger when he shot a nail into the end, and my nose when I broke it, and my nose after surgery to set it, so I get that not everyone thinks the raw things of life are interesting. So no glossies of poop. But, if there were photos, they would include: pig poop, goat poop, sheep poop, turkey poop, chicken poop, dog and cat poop. There's a book called, "Everybody Poops". This book is not a work of fiction. Poop is a problem because it's the carrier of things that do not belong inside our bodies. And, sometimes parasites and worms will invade to live in the warmth and ick that is poop. There are good worms. Helpful worms. In the spring I added Red Wigglers to my raised garden beds to help irrigate and nourish my soil. Night crawlers lure fish onto hooks so we can eat them. But mostly there are are gross worms. These are the, 'why did you create these things, God?', parasites that live in the guts of living beings. There are heartworm, pole worms, tapeworms, whipworms, and pinworms to name a few, When the animals poop worm pieces or the whole worm, will be in the feces. Then they are on the soil. When the animals graze that area, they ingest more parasites/worms. Parasites are not the only problem with poop. Poop attracts flies which then breed. This gives us creepy maggots and then more flies. Flies are nothing more than poop transporters. They alight on poop and then alight on garbage and then alight on poop and then alight on your wall, at which time you smack it and splat all the fly's souvenirs. Let's just say it: poop is nasty. Although, if we didn't poop, well that would be much nastier. When we developed our homestead or hobby farm plan, we knew right off we would engage in natural and organic practices. One of the reasons we raise chickens is to have eggs that have not been pushed through a hormone antibiotic laden hen. We use no pesticides on our vegetables or fruit trees. So, using chemicals to kill ground pests, no matter how foul they are, would be counter to what we believe. This is where Diatomaceous Earth or DE comes in super handy. Use caution when using DE. Use only FOOD grade DE and NOT POOL grade. DE is similar in consistency to a dusting powder. DE can irritate eyes, noses and lungs. We make sure the animals are not around when we spread it, because any wind or breeze can easily carry it to them. we don't want to subject them to any discomfort if possible. Chickens have fragile respiratory systems, so if you choose to use it in their coop as I do because it helps keep lice, flea, mosquito fly and mite populations down, use it after you've cleaned out the coop, and spread new bedding. Do not use it when the chickens are IN the coop. DE is also useful for parasites and pests on livestock. When we trim hooves, we liberally apply DE to the sheep and goats hides. Behind the ears, around the rear, and down the backs. It helps get rid of what might be there, and repel intruders. We like to use the DE product from Red earth. http://www.redlakeearth.com/red-lake-diatomaceous-earth-us.html We mix our own feed and use DE as a top dressing for natural deworming. Some folks also leave it as a free choice for their animals. I did read where a woman lost her chickens after spreading DE in their coop, but she spread it when they were in there, and she didn't indicate whether it was FOOD grade or POOL grade. So be careful when you use it. DE can also be used for flea control. We brought three flea infested barn kittens home. Kittens are so delicate and small you can't really use any typical chemical laden flea control products on them. Initially we bathed them in Dawn dish soap and used flea combs. We spread DE in their litter box, and their bedding and around the pool house where their food and beds are. We add DE to our cats food, too. This site has dosage recommendations and more information about worming our domestic pets with DE. I've always believed that God put on earth everything we need to live and be healthy. I don't understand some of the things he created, like fleas and muzzles and flies, but He knows what's He's doing. I started researching natural remedies back in the 80s We've planted herbs that we can use for cooking, but also we put fresh cut and dried herbs in the coop, where they turkeys are and in the livestock area. This includes mint, thyme, sage, peppermint, and lavender. Smells good and helps repel pests. If you can do a natural God given remedy, why not?? Using this life viewpoint, I've extensively researched the use of natural remedies, herbs, essential oils etch, and the news is good and fascinating. I didn't mean for this post to turn into a huge endorsement for DE, but it did. The second part will address the use of Essential Oils at Baldwin Acres. Thanks for reading. Have a beautiful day.
{'redpajama_set_name': 'RedPajamaC4'}
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Life, Podcast, Politics July 9, 2019 July 9, 2019 ATM: The Podcast — National Parks: Our Living Treasure Across The Margin: The Podcast celebrates the grandeur of America's National Parks with an interview with the author of National Parks: Our Living Treasure (A Time For Concern), Dr. Gil Lusk… On iTunes now! On Spotify now! In this latest episode of Across The Margin: The Podcast, host Michael Shields, with the help of author and National Park Service (NPS) authority Dr. Gil Lusk, celebrate the national treasure that is the United States' National Park System. Dr. Lusk is a retired National Park Service employee with thirty-five years of experience. For his efforts, he was awarded the U.S. Department of Interior's two highest performance awards: the Meritorious Service and Distinguished Service awards, the latter presented by the Secretary of Interior and the President. Dr. Lusk's book, National Parks: Our Living Treasure (A Time For Concern), recounts the origins and the rich history of the NPS, while also ushering readers into NPS's current conflicted era, where an abundance of issues endanger the important mission and preservation goals of the NPS. In this episode, Michael and Dr. Lusk converse over what makes the National Parks and the National Park Service so special, break down the crucial concerns facing the National Park Service (particularly politically), and climatically, Dr. Lusk suggest a series of urgent changes that are needed to bring the NPS back to its prime and ensure the protection of one of America's most wondrous treasures. Listen on iTunes • Listen in your browser A Time for Concern, Dr Gil Lusk, National Park Service, National Parks, NPS, Our Living Treasure, podcast Carson versus Carson: The Great Ben Carson Debate Across The Margin: The Podcast — DELANILA's Overloaded The Healing Power of Trans Love Statues Must Fall Previous articleMy Soulmate Speaks Only to Me Next articleTwo Poems by Robin Ray NEW T-SHIRT DESIGN IN THE SHOP! JOIN US & GET ACROSS THE MARGIN IN YOUR INBOX Writers & Wordsmiths. Join us! Fiction, Life Beautiful Morning
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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Claremont Road, Manchester The design of the scheme primarily aims to regenerate the site in a way which is sympathetic to the residential scale design, street scene and landscape of the site. The building is set back front the pavement and kept in line with the adjacent house at Claremont road. This detached house completes the streetscape. The palette of materials has been carefully selected to create variety within the development whilst maintaining a coherent design. The materials are arranged to complement the three-dimensional massing of the development. The design of the scheme primarily aims to regenerate the site in a way which is sympathetic to the residential scale design, street scene and landscape of the site. The building is set back front the pavement and kept in line with the adjacent house at Claremont road. This detached house completes the streetscape.
{'redpajama_set_name': 'RedPajamaC4'}
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Traditional data centre vs micro data centre deployments - who wins? Ashton Young Small data centres that are deployed at the edge of networks are growing in importance as the demand for digital services continues its relentless surge. According to Schneider Electric, many infrastructure vendors have responded with the development of self-contained prefabricated and highly integrated pods that allow small data centres to be deployed quickly, reliably and cost effectively. The energy management automation specialist has released a report that explains why prefabricated micro data centres are the future for edge computing as alternatives like traditional builds and server rooms are far more expensive options for doing the same job. As well as providing 'out of the box' IT infrastructure cost effectively and reliably, the paper proposes a future micro data centre architecture that could replace traditional enterprise data centres for certain applications. The report compared the cost effectiveness of a single traditional data centre of one MW capacity against a cluster of micro data centres each of 5kW capacity. So long as network latency is not a vital factor the micro data centre approach was found to offer considerable savings in capital expenditure because one does not have to build an entirely new facility and therefore can exploit the sunk costs in terms of building space, utility power, backup generators and cooling that has already gone into an existing facility. However, if some of the 200 micro data centres are geographically located away from the others, network latency might be affected, which means there could be some instances when the purpose built approach with all the IT in the same location will be preferable. Schneider Electric asserts an added benefit of prefabricated micro data centre infrastructure is that it can be combined to form the larger IT facilities many organisations require as their needs grow, but who cannot afford the larger up front costs of building a new traditional, or purpose built data centre. There are a number of drivers behind the growth in adoption of micro data centres, including scalability and the need to match increasing IT capacity more closely to expected load, speed of deployment to rapidly respond to changing requirements, reliability, and the desire to outsource applications to the cloud or colocation facilities. Schneider Electric says this last trend is a growing one that is frequently accompanied by a desire to keep certain legacy or mission critical applications hosted on infrastructure in house. Final result? It would appear the micro data centre approach would be ideal for smaller applications, but the traditional data centre wins out for the larger applications. Scale Computing delivers NVIDIA-powered HC3 appliances to market Schneider Electric Internet of Things / IoT Edge computing Micro data centre infrastructure Infrastructure
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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Law Of Granting Of Legal Personalities. Original Language Title: LEY DE OTORGACIÓN DE PERSONALIDADES JURÍDICAS. LAW OF MARCH 19, 2013 For the Plurinational Legislative Assembly, it has The following Act: LEGAL PERSONALITY AWARD LAW ARTICLE 1. (OBJECT). This Law is intended to regulate: I. The granting and registration of legal personality to social organizations, non-governmental organizations, non-profit foundations and civil entities who develop activities in more than one department and whose activities are non-financial. II. The granting and registration of legal personality to churches and religious groups and spiritual beliefs, whose purpose is not profit. ARTICLE 2. (CONSTITUTIONAL FRAMEWORK). I. This Law is part of the exclusive competence assigned to the central level of the State, in the numerals 14 and 15 of Paragraph II of Article 298 of the Constitution of the State, in respect of the granting and the legal personality to social organizations, non-governmental organizations, foundations, and non-profit civil entities that develop activities in more than one department. II. Also, this Law is framed in the provisions of Article 297 Paragraph II and Article 3 of the Article 21 of the Constitution of the State. ARTICLE 3. (APPLICATION SCOPE). This Law applies to: I. Social organizations, non-governmental organizations, foundations, and non-profit civil entities that develop activities in more than one department and whose activities are non-financial. II. churches and religious groupings and spiritual beliefs, whose purpose is not profit. ARTICLE 4. (DEFINITIONS). For the purposes of this Law and its Regulations, the following definitions are set out: Legal Personality. It is the legal recognition of legal fitness that is given to a non-profit civil entity, social organisations, non-governmental organisations and foundations, on sufficient capacity to be subject to rights and to contract obligations, in addition to carrying out activities that generate full legal responsibility, in front of themselves and versus third parties. Social Organizations. (a) a group of persons who, in the care of the territory they occupy and/or common activities and related interests that develop, organize and/or promote initiatives of common interest for their components and/or organize themselves for the exercise of social control. -Governmental Organizations. They are those entities governed by private law, which have a nature of social service, of assistance, beneficence, promotion and economic and social development, conformed by national and/or foreign, which with due recognition of the State, carries out development and/or non-profit assistance activities and whose activities are non-financial, with funds and/or own financing and/or external cooperation in the territory of the Status. Foundations. Are those entities (a) private law which, when constituted, has a lasting effect on the assets of which it is to be set up for special purposes of general interest for non-profit purposes and whose activities are non-financial and for the purpose of carrying out its activities obtain recognition from the State. Civil Entities without Lucro Fines. It is the set of private individuals who have the recognition of the State for non-profit and non-financial activities which tend to the common good. Registration of Personality Legal. It is the inscription of the encoding and alphanumeric classification of the document of granting of the legal personality that is given to the collective persons, whose information is stored in a database. RECOGNITION OF LEGAL PERSONALITY COLLECTIVE PERSONS ARTICLE 5. (RECOGNITION). I. Social organizations, non-governmental organizations, foundations and non-profit civil entities, whose scope of action and operation is greater than that of a department, must process their recognition of legal personality before the competent entity of the central level of the State. II. The recognition of the legal personality shall be granted through an express resolution. ARTICLE 6. (REQUIREMENTS). These are essential requirements for the recognition of legal personality: Public Writing of Constitution; Statute; Rules of Procedure; Approval Acts of the Statute and Rules of Procedure; Notarized Power of the Legal Representative; Other that are determined by the competent entity at the central level of the State, as Regulation. ARTICLE 7. (STATUTES). I. The statutes within its content must indicate minimally: Naming, nature, and address; Object and purpose; Of members, rights and obligations; Organization, internal structure, and attributions; Heritage and economic regime; Internal admission and admission arrangements exclusion of members; Disciplinary regime; Modification of the statutes; Regime concerning the extinction, dissolution and liquidation of the entity. II. The statutes of the non-governmental organisations and foundations, should mention in their content, additionally to what was required in the preceding paragraph: The contribution to economic and social development; The detail of the affectation of goods, in the case of foundations. III. Social organizations, non-governmental organizations, foundations and non-profit civil entities, should periodically register their sources of financing with the competent authority. ARTICLE 8. (COMPETENT ENTITY). The Ministry of Autonomies is constituted in the entity competent for the granting and registration of the legal personality to the social organizations, non-governmental organizations, foundations and non-profit civil entities, whose scope of action is greater than one department. ARTICLE 9. (COORDINATION SYSTEM). The collective persons will be able to form and constitute networks institutional or other entities of coordination and relationship, and must therefore deal with their respective legal entities, in accordance with this Law and its regulations. ARTICLE 10. (DENOMINATION). I. Non-governmental organizations should include the acronym? NGOs? II. Foundations must include the prefix? Foundation? antecedying to the name of the entity. ARTICLE 11. (PROHIBITION OF TRANSFER OF LEGAL PERSONALITY). Any form transfer and/or marketing of the legal personality of the collective persons is prohibited. ARTICLE 12. (AMENDMENTS). Any modification to the Statutes and Internal Regulations shall be processed in accordance with the provisions of this Law. ARTICLE 13. (NON-GOVERNMENTAL ORGANIZATIONS? NGOs and FOUNDATIONS FOREIGNERS). Non-governmental organizations and foundations incorporated abroad, shall deal with the Ministry of Foreign Affairs and the competent authorities at the central level of the State, the subscription of a framework agreement of basic cooperation with the Plurinational State of Bolivia, that allows them to operate legally in the territory. ARTICLE 14. (REVOCATION OF LEGAL PERSONALITY). legal personality will be revoked those collective persons who: Do not comply with the provisions of this Law and its regulations; Realize activities other than the purposes mentioned in your statutes. RECOGNITION OF LEGAL PERSONALITY TO RELIGIOUS AND SPIRITUAL ORGANIZATIONS RELIGIOUS AND SPIRITUAL ORGANIZATIONS). Spiritual organizations are the set of natural, national, and/or foreign persons who perform worship practices and/or beliefs for spiritual development and/or religious on the horizon of Living Well, whose purpose is not profit. ARTICLE 16. (SUBJECT MATTER). I. In respect and guarantee of the right to religious and spiritual belief of indigenous nations and indigenous peoples peasants and freedom of religion and spiritual beliefs, the granting of legal personality to the religious and spiritual organizations. II. Within the framework of Article 297, Paragraph II, of the Constitution of the State, the granting of legal personality to religious and/or spiritual organizations, as well as their Regulation, registration and control, is at the central level of the State Plurinational of Bolivia. ARTICLE 17. (LEGAL PERSONALITY OF RELIGIOUS ORGANIZATIONS AND SPIRITUAL). I. The churches and religious groupings and spiritual beliefs established in the constitutional framework, will have legal personality as religious and spiritual organizations, whose granting will be dealt with the Ministry of Relations Foreign, for formal recognition by the Ministry of the Presidency, by Supreme Resolution. II. For the purposes of their constitution and recognition, religious and spiritual organizations must present the documentation and requirements required by the Ministry of Foreign Affairs, as per Regulation. III. operation, supervision and revocation of the legal personality of religious organizations and spiritual, as well as registration for the granting of their legal personality, will be subject to regulation. FIRST. This Law may be used in an additional manner by the Autonomous Governments Departmental, in accordance with the provisions of Article 11 of Law No. 031 of 19 July 2010, the Framework of Autonomy and Decentralization? Andres Ibanez?. SECOND. The Regulation of this Law will be approved by a Supreme Decree, on a proposal from the Ministry of Autonomy, in coordination with the Ministry of Foreign Affairs, within a period of no more than sixty years. (60) business days from the publication of this Law. THIRD. For the purposes of registration, the collective persons who carry out activities in more than one Department and who obtained their legal status prior to the validity of this Law shall submit to the Ministry of Autonomies a legalized copy of its legal status within one (1) year of the publication of this Law. FOURTH. Within two (2) years of the publication of this Law, the religious associations with legally recognized legal personality, shall carry out the approval procedure before the Ministry of Foreign Affairs. After that period, the Ministry of Foreign Affairs shall revoke the legal personality granted. OPENING and REPEAL PROVISION ONLY. All provisions contrary to this Law are abrogated and repealed. FINAL DISPOSITION UNICA. For information compatibility purposes, the Departmental Autonomous Governments will refer to the Ministry of Autonomy the detail of the legal personalities of registered collective persons, according to Regulation. It is given in the Chamber of the Plurinational Legislative Assembly, five days of the month of March of two thousand thirteen Fdo. Lilly Gabriela Montano Viana, Lucio Marca Mamani, Claudia Jimena Torres Chavez, Marcelina Chavez Salazar, Marcelo William Elio Chavez, Angel David Cortez Villegas. Therefore, I enact it so that it has and complies with the law of the State Plurinational of Bolivia. Palace of Government of the city of La Paz at the nineteenth day of March of the year two thousand thirteen. FDO. EVO MORALES AYMA, David Choquehuanca Cespedes MINISTER OF RELATIONS FOREIGN AND ACTING PRESIDENT, CECILIA LUISA AYLLON QUINTEROS, Claudia Stacy Peña Claros, Amanda Davila Torres.
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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Vortex Optics began in 1986 with their motto of "People, Products, and Promises" and has no intentions of changing it today. Vortex continues to treat its customers like royalty offering only rugged products and keeping its promises. Innovative new products are developed with customer feedback and ideas in mind. If you ever have a problem with a Vortex product, Vortex makes it their problem because Vortex believes it's all about you.
{'redpajama_set_name': 'RedPajamaC4'}
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Women are one big emotional ball of hopeless romance, and deep inside, so are men. Let the love of your life know that love conquers all with flowers. For a budget-friendly price of only $68, this gift package consists of 1 dozen blue roses of only the freshest, choicest quality, arranged stylishly in a classy vase. This gift package is ideal for occasions for Roses, Valentine's Day, and occasions For Him. 1 dozen blue roses arranged in a vase with a blue puppy. Consist of mums and gerbera with blue puppy and 4 blue balloons in a basket with fillers and ferns. Women are one big emotional ball of hopeless romance, and deep inside, so are men. Let the love of your life know that love conquers all with flowers. For a budget-friendly price of only $68.00, this gift package consists of 1 dozen blue roses of only the freshest, choicest quality, arranged stylishly on a basket with chips ahoy cookies.
{'redpajama_set_name': 'RedPajamaC4'}
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Jerv vs Fredrikstad I'll try and be sure in goals in this game Norwegian 1st Division and I hope that there will be goals, because these two teams generally always play that way and I hope it will be the same this time. So Jerv is a team who is currently in the middle of the table in ninth place, however, they are not played with too many goals this season. Fredrikstad is a team who is playing this season and are currently running in 15th place even though they have a very solid team. I have to try with goals here, because I think it makes sense to try to something. We'll see, but I would say that it is very real, no doubt. Date: 06-06-2016 18:00 Category: Norway – Division 1 Fixtures – All matches L0 – 2 vs Vindbjart (A) Cup 27/04/2016 D2 – 2 vs Stroemmen (H) Division 1 01/05/2016 W1 – 0 vs Bryne (A) Division 1 08/05/2016 L0 – 1 vs Levanger (H) Division 1 12/05/2016 W1 – 0 vs Sandnes (A) Division 1 16/05/2016 D1 – 1 vs Mjoendalen (H) Division 1 21/05/2016 D1 – 1 vs Ull/Kisa (A) Division 1 29/05/2016 vs Fredrikstad (H) Division 1 06/06/2016 vs Raufoss (A) Division 1 12/06/2016 vs Hoedd (H) Division 1 19/06/2016 L1 – 2 vs Sandefjord (H) Division 1 30/04/2016 L1 – 3 vs Sarpsborg 08 (H) Cup 05/05/2016 W2 – 1 vs Ull/Kisa (A) Division 1 08/05/2016 L0 – 4 vs Mjoendalen (A) Division 1 12/05/2016 D1 – 1 vs Raufoss (H) Division 1 16/05/2016 L0 – 3 vs Aasane (A) Division 1 22/05/2016 W1 – 0 vs Hoedd (H) Division 1 28/05/2016 vs Jerv (A) Division 1 06/06/2016 vs Bryne (H) Division 1 12/06/2016 vs Kongsvinger (A) Division 1 19/06/2016 Fixtures – Head to Head Fredrikstad 1 – 0 L Jerv Division 1 29/06/2015 Jerv 4 – 0 L Fredrikstad Division 1 23/08/2015
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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Black October What people of Catalonia and Spaniars have experienced the last October has had a great impact on the feelings, usual talks and way of living of thousands of citizens. Overall, a black October. Spanish version and photographs The month started with an uncommon day. Hundreds of Catalans going to vote, which was not authorized by the Spanish State; police and civil guard interrupting in schools; people disarmed and with their arms raised, shouting democracy, … and blows, many blows. What Europe and the world saw of that fateful October 1st was the beginning of a black month. As regards the successive days, everything could be summed up in fears of having found a way out, in ambiguous speeches, in the "reading between the lines", in "now it is on your roof", between the central government and the Parlament of Catalonia. The struggle reached its highest point by applying the article 155 of the Spanish Constitution by the Government of the Popular Party – after acceptance of the Senate – and the Declaration of Independence unilaterally approved by the Parliament of Catalonia on the 27th October. A month in which the media has not stopped a second to broadcast what was happening in Catalonia – with more or less success; a month in which citizens have contemplated astonished, angry and heartbroken – I included – how Catalan institutions were neglected, both by the suspension of the Autonomy in application of article 155 as for the absolute taking of the Parliament by the pro-independence parties; how the gap between separatism and the so-called "unionism" increased; a month where, informatively, only the Catalan same old story has existed. But, still, that has not been the worst. The crisis in Catalonia, as they say, is also the crisis in Spain and in Europe. This is an editorial blog, in which I and anyone can express their feelings. So, I will write here some thoughts. Would it be so bad that a historic town, with its own culture and traditions, with its own and recognized language, with six years of massive demonstrations in favor of the same idea, with a majority of the Parlament chosen in favor of that idea, could they have self-determination? Would it be so bad that Democracy could be used – that word with which now many fill their mouths up without knowledge – so that all parties could have an opinion, debate and finally endorse the solution in the polls? Would it be so bad if Carles Puigdemont and Mariano Rajoy talked like normal people? October started in a black way and finished in the same way. With its own ups and downs, which is a costly process, massive street demonstrations for and against independence – almost every weekend -, the imprisonment of the "Jordis" and successive "protests with pots and pans" from the Catalan balconies, last Friday 27th of October everything was blurred and the parties that should have sitted down and negotiate, went straight, getting the population lumbered with the problem. Now and always, if you are not in favor of the independence cause, you are automatically in the "Spanish" cause and the words "facha" or "unionista" appear in the mouths of those who call themselves democrats. In the same way it looks on the opposite side. "Separatists" or "breaking Spain" are common ways of describing those who support independence. These words are not a mere insult. Some will say them as a joke, but they are the result of division, confrontation and ignorance. To give an example, Joan Manuel Serrat was called "fascist" for stating that the 1-O referendum was not transparent. The "procés" has tested the feelings of many people. Politicians, determined to destroy and humiliate the opponent, have got themselves involved in a race where everything counts. It could have been a nice process, thinking about a reform to change whole Spain – starting with a reform of the Constitution and rewritting the role of the autonomies. Instead, it has becomen a nightmare that nobody knows how it will end. Given what we have seen, self-criticism is necessary. The government headed by Mariano Rajoy, for his stubborn resistance to listening and the negligence with which he has dealt with the Catalan issue during these years – starting with himself when in 2006 he promoted a collection of signatures for the "Estatut" (a kind of legal rights for catalans) to be voted on throughout Spain; Carles Puigdemont and all his advisers, in addition to the parties that bet for independence, to justify their actions in a referendum that clearly did not meet any standard from the moment the first ballot box was withdrawn; the media, to saturate and, in some cases, dramatize the situation in Catalonia and the vision towards the rest of Spain; the pro-independence entities, ANC and Omnium Cultural, for trying to decide on the future of Catalonia from outside the Parlament; those who are dedicated to inflame, whether in our out the government, the opposition, lawyers, judges, journalists, or ordinary people, for misunderstand the "Catalan conflict". Now, with a president dismissed abroad, with a search and arrest warrant, and his government also stopped in prison for crimes of rebellion, sedition and embezzlement, among others, the independence movement has a new reason to continue believing. Many, after the proclamation of the Catalan Republic on 27-O and with the passage of days without any clues as to how that republic was going to be configured, they looked with contempt at all the sovereignty discourse. Not now. Meanwhile, the central government washes its hands in anticipation of the regional elections on December 21, although at this time I am sure 'Pablo Casado', Communications vice-secretary of the Popular Party (PP) is saying among his people "I told you Puigdemont" when he compared the future of the Catalan politician with the former president of the Generalitat Lluís Companys. There are no magic solutions, but the imprisonment of the government and, surely, also of Puigdemont, does not fix things. It sharpens a political problem, with capital letters and, most worrisome, leaves the Spanish justice with one foot inside and one outside the executive power, something that undoubtedly truncates all hope that there is separation of powers in Spain. And I ask myself, who are the real victims here? Coexistence, something that made Catalonia proud because it is a plural and diverse territory, has been broken. The journalist Jordi Évole already said it in a television program. Coexistence is something very easy, but also very fragile. October 1st began with crying and the month ends in the same way. And the people, as always, pay the consequences.
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Q: Electron recoil after emitting virtual photon Assume that a stationary electron $A$ emits a virtual photon with $4$-momentum $k$ and a stationary electron $B$ absorbs it. Let us assume a description in which time is moving forwards. At the instant that electron $A$ recoils with $4$-momentum $-k$ can we say that the photon has $4$-momentum $k$? I assume not as this would imply that the photon is real with a definite $4$-momentum. It seems to me that, under the assumption that time is going forwards, we can only assert that electron $B$ has $4$-momentum $k$ once the virtual photon has been absorbed. So how can we understand electron $A$'s recoil? Let us assume a description in which time is moving backwards. In that case electron $B$ emits a virtual photon with $4$-momentum $-k$ and electron $A$ absorbs it. Now we can describe electron $A$'s recoil with $4$-momentum $-k$, without implying a real photon, again once the time-reversed virtual photon has been absorbed. So to fully describe the exchange of a photon between electron $A$ and electron $B$ it seems to me that we need to assume time both goes forwards and backwards. Is this right? A: Feynman diagrams are the generic mathematical model algortithms that describe particle interactions and define "virtual", as in "virtual photon". How is this algorithm changed into a mathematical formula which will give finally the probability of electron positron elastic scattering? There exists a one to one correspondence with each vertex and each line to a mathematical form. The symbolic graph allows us to visualize the interaction as an exchange of a virtual photon, it has all the quantum numbers of a photon except it is off mass shell. Off mass shell means that its four energy/momentum vector does not retain its "length" , the "length is the rest mass, it means that it is off mass shell, i.e. for the mass of the photon is different than zero. This means that energy and momentum conservation for the process can only be imposed to the incoming and outgoing lines ( and the vertices on them), and are irrelevant on a virtual line because the four momentum exchanged between the electron and positron is carried pictorially by the virtual photon whose mass is unphysical. This definition of virtual holds for all particle internal exchanges between vertices. It has no meaning to speculate about the distances and times, which will be unphysical, only the result of the final integration of the whole formula has physical meaning. Talking of "virtual" particles helps us in writing the propagator because the rest mass of the real particle enters there, and it helps us keep track of the quantum numbers. It is a mathematical representation that works beautifully but it is a mistake to extend it to a realm where it does not apply: one cannot verify or experiment in the virtual space and validation comes from experiments agreeing with the total computation. So a thought experiment within the virtual regime has no meaning in momentum conservation or time direction, it cannot be carried out since the particles are "virtual", as defined above. A: No, time does not "go backwards". This expression is sometimes used to say that the real parameter $t$ describing time instant can be run backwards, but this happens only in the mind of the theorist. The mathematical concept of time is used in such a way that it always increases along the progression of every physical process, that is past events have lower $t$ and future events have higher $t$. In relativistic theory, if body(electron) sends a packet of energy in one direction, it has to send momentum as well and if we believe in conservation of momentum, the body has to either recoil back as soon as it sends the packet or it has to send more than one packet, in such a way as to conserve the momentum. In relativistic theory, as soon as this happens, the mass of the electron has to decrease, which was never observed - all electrons have the same mass. So my view on this is that electron does not send packets of energy in definite direction. Electrons send EM waves that can together carry energy around, but most of the time, this does not come from the masses (internal energies) of the electrons, but is just present in the space around the particles.
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In week 39 we were able to carry 44% of the volume that normally runs via Rastatt over diversionary routes. Thanks to other measures such as barge service on the Rhine and additional departures from our terminals south of Rastatt, we could offer around 50% of our normal capacity. International cooperation between infrastructure managers is slow. As a result, railway undertakings are not able to fully exploit the theoretically existing train path capacity, and some trains are running with extreme delays of several days. As a result, in week 39 we were able to carry 44% of our normal volume on the diversionary lines.
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Q: WebServlet annotation not working in production (works in development) I am using Google App Engine STANDARD (SDK 1.9.62) and have set my appengine-web.xml to use java8 runtime and trying to get a simple servlet example. Works as expected in local dev server but gives me a 404 error in the google cloud. I WANT to use the Google App Engine standard environment (not flex). Is there a yaml entry or xml entry I need to turn on for this to work? How can I be sure that GAE is using the 3.1 servlet spec and not 2.5? A: App Engine Standard uses appengine-web.xml, whereas Flexible uses app.yaml. Now, this Java-docs-sample us using the pom.xml to set dependencies. you can see the versions of the dependencies set there. In this case, that sample can be deployed with mvn appengine:deploy and the endpoint serving in App Engine would be /requests. i.e https://project-name.appspot.com/requests which should return a "hello, world" A: Ok. Mystery solved. I had two versions running in deployment and an original java7, servlet 2.5 api version was handling all traffic. My INTENDED version, which was a java8, servlet 3.x was sitting idle and getting 0% traffic. Once I used the version migration function in google's cloud console, the servlets annotated with servlet 3.x annotations started working.
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Web Hosting Reviews Of ewsHOSTING. Find customer reviews about web hosting companies Listed In Compare Web Hosts Directory. We appreciate your time and effort to find out experiences other ewsHOSTING customers have had hosting their website. We hope this information helps you to make a decision and hopefully purchase a web hosting plan from ewsHOSTING. Be the first to post review for ewsHOSTING. ewsHOSTING - established in 2000. Our Windows Web Hosting services include 500MB of disk space, 5 GB of data transfer per month as well as many more features, including ASP, ASP.NET, PHP, FrontPage Support, mySQL and MS Access Database support.
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Вади́м Никола́евич Венеди́ктов (7 декабря 1937, Кировград, Кировградский район, Свердловская область, РСФСР, СССР — 5 мая 2020, Волгоград, Россия) — советский и российский дирижёр, педагог. Заслуженный деятель искусств РСФСР (1986). Биография Вадим Венедиктов родился в городе Кировграде. Обучался игре на фортепиано в музыкальной школе, однако после её окончания поступил на моторный факультет Казанского авиационного института, преодолев конкурс из 10 кандидатов на место. Венедиктов рассматривал перспективу карьеры офицера-подводника, когда ему в конце первого курса через военкомат предложили поступить на учёбу в Ленинградское высшее военно-морское училище. Однако медицинская комиссия училища не приняла Венедиктова, обнаружив у него пониженное цветоощущение. Тем же летом поступил на механический факультет в Казанский химико-технологический институт, также преодолев большой вступительный конкурс. О своей учёбе в химико-технологическом институте Венедиктов говорил: «Я успешно проучился два с половиной курса. Меня знал, кажется, весь институт. Я стал самым народным артистом всего вуза: и играл, и аккомпанировал певцам на всех вечерах всех факультетов и курсов… Меня на части рвали в самодеятельности. Я еще играл в эстрадном оркестре, руководил которым Георгий Яковлевич Ротт — тот самый, что был концертмейстером у Вертинского за рубежом. Он был аранжировщиком оркестра Олега Лундстрема и потрясающим пианистом Казанской филармонии. Именно его я считаю своим первым педагогом по инструментовке, по аранжировке.» Тем не менее Венедиктов принял решение оставить на третьем курсе институт и в середине учебного года, когда время вступительных экзаменов уже давно прошло, поступил в Казанское музыкальное училище по специальности фортепиано, но продолжил учёбу и окончил училище по классу фагота в 1962 году. В 1966 году окончил оркестровый факультет Казанской государственной консерватории по классу фагота доцента Н. Г. Зуевича. После окончания консерватории поступил на работу в недавно созданный при участии Натана Рахлина симфонический оркестр ТАССР в качестве фаготиста, через год Рахлин принял Венедиктова в консерваторию на учёбу во вновь открывшийся класс оперно-симфонического дирижирования, который Венедиктов окончил в 1972 году. В последующие годы Венедиктов руководил эстрадным квартетом Татарской государственной филармонии имени Г. Тукая, работал ассистентом главного дирижера симфонического оркестра ТАССР, дирижером симфонического оркестра Омской филармонии. В 1976—1989 был главным дирижером, в 1999—2000 художественным руководителем Музыкального театра Марийской АССР в городе Йошкар-Ола. В 1989 году Венедиктов принял приглашение на должность главного дирижера Волгоградского театра музыкальной комедии, а затем основал и возглавил как художественный руководитель новый проект «Волгоградская оперная антреприза», в дальнейшем реорганизованный в новый государственный театр «Царицынская опера» на основе уже сложившейся к тому времени антрепризной труппы. С 2004 года занимал в театре «Царицынская опера» должность дирижера-постановщика. Венедиктов погиб, выпав с балкона своей волгоградской квартиры на седьмом этаже. Деятельность Венедиктов многократно работал как приглашённый дирижёр с симфоническими оркестрами Казани (с 1966), Волгограда (с 1988) — в том числе на гастролях в странах Европы, Воронежской филармонии (с 1995), Саратовской филармонии (с 1996), Самарской филармонии (с 2004), а также с оркестрами театров оперы и балета Самары (с 1985), Татарстана (с 1989) — в том числе на гастролях в Голландии (2003). Также сотрудничал за рубежом с симфоническим оркестром Белграда (1996), и при сотрудничестве с Фондом Ирины Архиповой — с Корейским Симфоническим оркестром (Южная Корея, 2004). В пору руководства оркестром Музыкального театра Йошкар-Олы Венедиктов выступал активным пропагандистом творчества марийских композиторов, исполняя в концертах произведения Э. Сапаева, К. Смирнова, Я. Эшпая, Л. Сахарова. Ряд творческих вечеров и премьерных исполнений сочинений Андрея Эшпая осуществлён благодаря многолетней дружбе и творческому сотрудничеству композитора с Венедиктовым. В рамках проекта «Волгоградская оперная антреприза» Венедиктов выступил дирижером-постановщиком оперных спектаклей «Севильский цирюльник» Дж. Россини, «Тоска» и «Мадам Баттерфляй» Дж. Пуччини, «Евгений Онегин» и «Иоланта» П. И. Чайковского, «Паяцы» Р. Леонкавалло, «Кармен» Ж. Бизе, «Сельская честь» П. Масканьи, и «Человеческий голос» Ф. Пуленка. С 2000 года осуществлял музыкальные постановки спектаклей Волгоградского муниципального музыкального театра. Среди постановок, осуществлённых Венедиктовым для этого театра, обозревателями были особо отмечены оперы «Травиата» Дж. Верди и «Амок» Б. Синкина, оперетты «Мистер Икс» и «Фиалка Монмартра» И. Кальмана, мюзиклы «Биндюжник и Король» А. Журбина, «Американская любовь» В. Колло. Вклад Венедиктова как дирижёра-постановщика столь масштабных проектов сделал возможным в 1995 году получение Волгоградским театром музыкальной комедии официального статуса Музыкального театра с разножанровым репертуаром. С коллективом Волгоградского музыкального театра Вадим Венедиктов гастролировал в Курске, Орле, Севастополе, Сочи, Туле. В архивах Центрального телевидения хранятся записи многих концертных и симфонических программ Венедиктова. Профессор Венедиктов работал также в Волгоградском институте искусств и внёс значительный вклад в создание там в 2000 году симфонического оркестра студентов кафедры музыкально-инструментального искусства и долгое время руководил и дирижировал этим коллективом. Именем Венедиктова в 2019 году назван камерный зал театра «Царицынская опера». Награды и звания Заслуженный деятель искусств РСФСР (1986) Лауреат Государственной премии Марийской АССР (1979) Заслуженный деятель искусств Марийской АССР (1980) Государственная премия Волгоградской области Орден Почёта Семья Сын — Алексей Венедиктов, заслуженный артист России, концертмейстер группы ударных Волгоградского академического симфонического оркестра, преподаватель ДМШ № 8 Волгограда. Примечания Ссылки «Музыка моей души» — выпуск программы «Волгоград театральный», посвящённый памяти Вадима Венедиктова. Муниципальное телевидение Волгограда. Выпускники Казанской консерватории Академические музыканты России Музыканты Татарстана
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Improving Macro-Economic Evironment Can Send Gildan Activewear Inc (USA) (GIL) Soaring Published on June 10, 2013 at 12:57 pm by The Motley Fool in News Gildan Activewear Inc (USA) (NYSE:GIL) is a vertically-integrated manufacturer of branded basic family apparel, including T-shirts, fleece, sport shirts, socks and underwear. It possesses a vastly diversified portfolio of company-owned brands such as Gildan Activewear Inc (USA) (NYSE:GIL), Gold Toe and Anvil brands. In addition, it is also under licensing arrangements for Under Armour Inc (NYSE:UA) and New Balance. The company primarily operates in two segments, printwear and branded apparel. The branded apparel segment deals predominantly in subtle fashion or plain T-shirts, fleece and sport shirts, which are sold to wholesale distributors and subsequently sold to screen printers that print logos and designs on them. The company distributes print wear to the U.S. and Canada, where Gildan Activewear Inc (USA) (NYSE:GIL) is the industry-leading brand. The company is gradually shifting focus from existing markets in order to increase its international footprints. Moreover, Gildan is trying to incrementally develop and grow its presence as a consumer brand distributed through U.S. retailers. It must be noted by potential investors that Gildan Activewear Inc (USA) (NYSE:GIL) holds a leadership position with approximately 70% share of the print wear market. The company's manufacturing facilities are strategically located in Central America and Caribbean. Additionally, it also owns a small manufacturing center in Bangladesh (textile hub of the south Asian region) in order to address its markets outside the United States and Canada. Gildan Activewear Inc (USA) (NYSE:GIL) outperformed market expectations during the second quarter of 2013. Beating the earnings estimates, it reported an EPS of $0.59, compared to the earlier forecast figure of $0.57. Furthermore, the company clocked a staggering growth rate of 168% in earnings. Revenue figures posted an 8% growth over the previous year quarter. The impressive growth exhibited by the company can be attributed to key acquisitions made during the period. Key Acquisitions In an effort to increase its market penetration, the company acquired a 100% stake in Gold Toe Moretz for $345 million. The acquisition was completed to prop up the sales growth of socks and capitalize on Gold Toe Moretz's sourcing network to introduce new products within its existing channels of distribution. Gildan Activewear Inc (USA) (NYSE:GIL) also acquired Anvil for $88 million in order to grab a larger share of the printwear market. The synergies gave a giant push to the company, which allowed it to successfully sustain its leadership position in the printwear segment. The world market for branded apparels is expected to reach the $600 billion mark by 2015; moreover, the share of the US is estimated at approximately 30%. Gildan with its focus on the US market has a huge growth potential. With APAC expected to grow at an estimated CAGR of 2.5%, the company should make deeper inroads into large emerging economies and gradually increase its global market share. Potential roadblocks Cotton prices have a direct impact on the firm's operating margins and overall profitability. Steep rises in the global cotton price during 2010 and 2011 had a direct impact on the company's earnings, as the firm reported a loss of $46.1 million during the firstquarter of fiscal year 2012. Investors should note that it was only its second quarterly loss since the company went public in 1998. Although cotton prices have receded to normal levels for now, any fluctuations in the future could have an adverse impact on the firm's earnings and margins. Cotton is an agricultural commodity, hence climate plays a crucial role in global harvest. Any significant climate changes could hamper production levels and impact prices of cotton bales. Gildan reported net sales of $1.94 billion during fiscal 2012, out of which international sales stood at $141 million. With the U.S. economy in a recovery phase it is important for the company to enhance its global presence and diversify into new emerging markets to bolster its earnings. Post the 2008 subprime crisis, the U.S. economy tanked, giving rise to massive unemployment and credit squeezes, which led to a steep decline in consumer spending. To deal with this issue, the Federal Reserve introduced quantitative easing, which is an unconventional tool to increase monetary supply and subsequent credit availability. Post-QE the U.S. economy marginally stabilized with the unemployment rates falling and growth picking up. However, these are still testing times, as massive budget cuts still loom around the corner. A poor macroeconomic environment in the North American markets still poses a massive threat to the company, as a large percentage of its sales are generated from this region. Gildan's primary competitors across segments are Hanesbrands Inc. (NYSE:HBI) and Berkshire Hathaway Inc. (NYSE:BRK.A). Hanesbrands Inc. (NYSE:HBI) has been one of the best performing in its segment. It reported a profit of $54 million during the first quarter of fiscal 2013, which is a huge improvement from the same quarter the previous year, where the company reported a loss of $27 million. Although revenue decreased by 2.8%, increases in gross margins at around 8% provided the necessary impetus for strong earnings growth. With the Innovate-to-Elevate strategy the company aims to further penetrate the market and challenge Gildan's leadership in North American. Its recent jump in earnings has resulted in several investors keeping a highly bullish view on its stock. Berkshire Hathaway Inc. (NYSE:BRK.A)'sFruit of the Loom and Russell Corporation are other key competitors. A legal battle between the two has led to Gildan settling the issue with a $1 million compensation to Russell over the trademark infringement issues. The rivalry between the companies has been ongoing for decades, and in spite of the acquisition of Fruit of the Loom and Russell Corporation by Warren Buffett's Berkshire Hathaway, Gildan has been able to outperform its competitors and sustain its leadership position in the North American markets. Why this stock could be a good buy Gildan's fundamentals are strong, and coupled with strategic acquisitions recently made, Gildan is becoming the largest sock producer in the world. The company controls almost 70% of the North American market, which is indicative of its true dominance. In addition, the company has strategically located production facilities, which allow it to maintain competitve pricing. It is a leader in its segment, and going forward even a marginal increase in consumer spending could send its share price soaring. Kiran Gulati has no position in any stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. Kiran is a member of The Motley Fool Blog Network — entries represent the personal opinion of the blogger and are not formally edited. The article Improving Macro-Economic Evironment Can Send Gildan Soaring originally appeared on Fool.com is written by Kiran Gulati. Gildan Activewear Inc (GIL)Hanesbrands Inc. (HBI)NYSE:BRK.ANYSE:GILNYSE:HBI DIRECTV (DTV) Bears Will Get Slaughtered Hedge Funds Are Betting On Under Armour Inc (UA) Warren Buffett News: General Motors Company (GM) Boost, Berkshire Hathaway... eBay Inc (EBAY), Berkshire Hathaway Inc. (BRK.A): Buffett Charity Lunch Auction... Hanesbrands Inc. (HBI), Gildan Activewear Inc (USA) (GIL), Coach, Inc. (COH... Exelon Corporation (EXC), Ameren Corp (AEE), TECO Energy, Inc. (TE) &... Published on June 10, 2013 at 12:57 pm by Inan Dogan, PhD
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But they will. I still have drivers from computers I no longer have for nostalgia. I might come across the same model and don't have to search for drivers or updates. Looking at that MS article, it references Winhttp.dll and Updspapi.dll. The former is now the correct version on my system (5.1.2600.7587) but the latter, although there are many old instances of it in previous update folders, does not exist in my \system32 folder. Is that correct? I always thought Updspapi.dll was a file which was just part of the update mechanism, but searches about it seem to often say that there should be a copy of it in \system32. It is part of the update mechanism. I don't think it's needed in \system32, although a copy of it may find its way there by mistake. None of my 6 current XP installations has it \system32, although all have many old instances of it in previous update folders, many of them of the same v. 6.3.13.0, despite being different compilations (= having different dates). Thanks den, that was what I was assuming! This is the problem I have: On Windows 7 I use Previous versions, and every time I plug my USB hard drive on my Windows XP and after that I plug it on my Windows 7 I loose all the snapshots of this drive, with this error: volsnap event ID 29: The shadow copies of volume F: were aborted during detection. Version 5.1.2600.5512 of volsnap.sys is the latest, AFAIK. However, the missing KB article is still findable here: https://web.archive.org/web/20110222004859/http://support.microsoft.com/kb/926185 and seems to offer a solution. HTH. I think there is no solution for my case, cause the solution they offer is to disable the volume in Windows XP so it can not delete the shadow copies. In my case I want to access my USB drive from Windows 7 and Windows XP. That's why I hoped there were some hotfix for this issue and a new version of volsnap.sys. I tried to disable the driver volsnap.sys but I get a BSOD. Anyway I don't know why they didn't fix this with an update for volsnap.sys for Windows XP when Vista came out in 2006, cause this could lead to an important data loss. Because they couldn't care less for multibooters then, than they care now. A multibooter, by nature, does not use just their latest and greatest OS, and that makes her/him an unperson. That original version is the only one I know of. That USB drive, are you using it for backups from a backup type program, or is it something you use to make manual copies with? Do you write to it from both W7 and XP, or only from W7 and just do reads from XP? If XP usage is going to be read-only, you could try setting the volume mount for the USB drive in XP to be read-only rather than the default read-write mount. IIRC there was a regedit or something to make this change, I don't have it handy right now but maybe someone else remembers it? That might keep XP from destroying the W7 shadow copies there. You might want to change the settings for System Restore in both XP and W7 to not monitor that USB drive, maybe even delete the restore points stored on it (if any), at least that should avoid creating new ones that would corrupt the shadow copies. Another possibility is to tell W7 to store the shadow copies for the USB drive elsewhere, like maybe on the W7 system drive (hopefully XP will not have access to that so can't delete them). See https://ccm.net/faq/2679-how-to-turn-off-volume-shadow-copy#how-to-edit-the-disk-space-allocated-to-shadow-copy for instructions. Do you also use Previous Versions on XP? I think it did not come by default (at least on Home) but have seen some people claim it can be installed there, from https://www.microsoft.com/en-us/download/details.aspx?id=16220. While XP does have a copy of vssadmin.exe, it is older than the W7 version and I'm not clear if it is able to do the same thing and move its snapshots of the USB drive to the XP system drive (where hopefully W7 will not delete them), but if it is able you could try that too. I don't know whether installing the volume shadow service SDK on XP would help or not, but it is available at https://www.microsoft.com/en-us/download/details.aspx?id=23490 if you want to check that out. You probably don't want to disable the driver for volsnap.sys since it would be needed by the shadow copy service that runs by default. If you want to stop the service itself there are also instructions for that a bit earlier in the above ccm.net link, this should be the same for both XP and W7. In that case you might also want to turn off the Microsoft Software Shadow Copy Provider service, similar method but different name. Both of these services can be typically called by backup programs including MS Backup and also System Restore so if you use those this might not be a good idea. More info about these services is at http://www.blackviper.com/windows-services/volume-shadow-copy/ and http://www.blackviper.com/windows-services/microsoft-software-shadow-copy-provider/ . Why this fix is not trivial for Windows XP: Backporting volsnap.sys to Windows XP would require significant development and testing time. The entire Volume Shadowcopy Service (VSS) subsystem in Windows Server 2003, Windows Vista, and Windows Server "Longhorn" would need to be backported to Windows XP and would likely break a number of third-party backup applications that rely on the current version of volsnap.sys in Windows XP. for whatever THAT may be worth. Hi w2k4eva, thanks for your answer. I want to read and write the drive from XP and 7. I don't use system restore on XP, I use it on 7. I disabled system restore and VSS service on XP but it is the XP driver volsnap.sys that removes restore points and previous versions from Vista and later, and it cannot be disabled. So the only "solution" is never use a drive with Vista or later shadow copies on Windows XP. I think the only trivial fix they could have done was to modify volsnap.sys to recognyze Vista shadow copies an NEVER, EVER touch them. Cause is inadmissible that an O.S. removes anything from an external drive. I agree there should be a fix for volsnap.sys to ignore shadow copies from later versions. But I guess there's not. ... tell W7 to store the shadow copies for the USB drive elsewhere, like maybe on the W7 system drive (hopefully XP will not have access to that so can't delete them). See https://ccm.net/faq/2679-how-to-turn-off-volume-shadow-copy#how-to-edit-the-disk-space-allocated-to-shadow-copy for instructions. On W7, it appears you'd use the command "vssadmin resize shadowstorage /On = C: (assuming C: is your W7 system drive) /For = D: (assuming D: is your USB drive) /maxsize = 3GB (or whatever)". Which, if I understood the article correctly, would place the shadow copies of D: on your C: drive. Then there's nothing left on D: for XP to mess up. It has to be seen if volsnap.sys actually hooks also this IMDISK volume (that appears not in disk manager, etc. as it is basically a "superfloppy"). Hi Mathwiz, yes, a solution could be that one, but in my case I don't want to store the shadow copies in another drive. So for me the solution for now is to use another drive. Hi jaclaz, I have to look at your possible solution, thanks.
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The mayor, in his third year in o ce, will present a budget to City Council for approval in March. Photo by Jon Mirador. Richmond Mayor Levar Stoney announced the details of new programs aimed at eviction diversion and city improvements in his annual State of the City address Jan. 31. At his speech at the Virginia Museum of History & Culture, Stoney announced an eviction diversion program and a 20-year capital improvement plan. Stoney highlighted the city's accomplishments and mapped out his future plans — some of which span 20 years. The eviction diversion program will provide financial literacy education, access to supportive services and a payment plan for landlords who lose rent during the eviction process. It will be the first program of its kind in the commonwealth. Other strategies to reduce eviction include court mediation and pro bono attorneys to support tenants. Richmond City Council member Chris Hilbert said he supports the program, which will be presented to the council in March as part of the mayor's proposed budget. The meeting is yet to be scheduled. The city budget also includes a 20-year capital improvement plan, which will invest resources in streets, community centers and city transportation. Stoney's speech included details of three Richmond schools opening in 2020, and a 20-year plan to renovate Richmond schools with $800 million. Stoney also called on the state legislature to increase school funding, following an education rally held at the Capitol Jan. 28. Stoney said teacher salaries, school facilities, technology, nurses, counselors and bus drivers need sufficient funding. The Richmond mayor, in his third year in office, announced the establishment of the Shockoe Alliance, a collaborative effort of city government members and Shockoe Bottom residents to design and plan the future of the Shockoe Bottom area. In the spring, the alliance will announce a "vision forward" for the Shockoe area, Stoney said. Shockoe Bottom was home to one of the largest slave trades in North America prior to the Civil War. "Telling the true story of the tragic history that occurred in Shockoe can be the most inclusive history told anywhere in America," Stoney said. Stoney's plans for his third year in office also include renaming Boulevard after tennis player and humanitarian Arthur Ashe. City Council will vote on the plan Feb. 11. Before Stoney took office in 2016, Richmond's score on the Human Rights Campaign's Municipal Equality Index, which measures a localities responsiveness to the LGBTQ community, was 46 out of 100. In efforts to improve that rating, Stoney and councilmembers Parker Agelasto and Ellen Robertson launched Richmond's first Human Rights Commission last year. Richmond's rating is now 94 out of 100. Richmond's unemployment rate has dropped to 2.9 percent from 4 percent in 2016. The median household income rose 5 percent, one of the highest increases in the nation, Stoney said. Last year, Richmond saw an 8 percent decrease in overall violent crime. The homicide rate dropped 20 percent. Stoney plans for all Richmond police officers to be certified in crisis intervention within two years.
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It has already been over a month since we were in Tucson and it feels like it was just a week ago! The end of the Road to Tucson Sweepstakes is fast approaching and all entries MUST be in by Wednesday, March 16, 2011 at 11:59PM Pacific Time. The Grand Prize winner will win a trip for two to the 2012 Gem and Mineral Show that includes airfare, hotel accommodations, transportation and a beading class! I think Tucson experience is something you will never forget. Here are some more pictures I took this year as well as some of the things you will see and do. 1. Take classes with famous and talented instructors. 2. See amazing jewelry designs from the world's best jewelry artists. 3. See endless gemstones and fossils. Most are bigger than you would imagine! 5. Find the latest and hottest new products and trends in beads and jewelry. 6. You never know who you're going to meet! I met up with Libbey from Fire Designs about what inspires her. She said fashion trends, color and her customers inspire her! She has a great eye for color with fun bright colors that add a little more to your designs. We want to share the experience with you! Get your entry in to the Road to Tucson Sweepstakes by 11:59PM Pacific Time on Wednesday, March 16, 2011. Tell all of your friends and family to enter, maybe they will bring you! We will choose the winner on March 17, be sure to check your email to see if you won. Looks like a great experience!!!
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A: EcoFoam retrofit wall insulation is a product that is specifically designed to be used for this application. It is pumped into the cavity as a foam with the consistency of shaving cream and then sets into a very lightweight solid that never settles or sags over time. A: An electrical inspection and preparation is part and parcel of our application method. Q: I have a shed 5.5 x 5.6 that I'm looking to have insulated. Is there a difference in price for inter/ exterior roof insulation? also, which methods provides the best insulation from heat? I will have animals inside the shed and need as much insulation from heat as possible. A: There are quite a few factors to consider in determining whether an internal or external application will be more cost effective. In general, it is more cost effective to install the spray foam insulation direct to the underside of the roof. This eliminates the need for additional UV protective coatings that would be required if the sprayfoam was applied ontop of the roof. You then have to consider the interior access conditions and the amount of masking (if required) to existing equipment/surfaces inside the spray area. Both methods would provide very similar results in terms of the effectiveness of the insulation. The external application would technically provide a slightly better result by the fact that the heat is hitting a painted foam surface as opposed to a metal roof but this is normally offset by the reduced cost of an internal application which can be applied slightly thicker to offset the difference. Q: I own a standard 3 bedroom cavity brick home in Bathurst NSW, built circa 1970. I am looking for quotes to install retrofit wall insulation. Does your company service the central tablelands and if so, what would be a rough idea of the cost of installing this insulation? A: Thanks for your enquiry. Yes, we are able to service your area and will be in touch shortly to provide you with an estimate. EcoFoam have the perfect solution for insulating the existing walls of any old home. Contact us to find out how we do it and how you can start saving money on your energy bills. "My name is Greg and I live in Canberra. My house is over 50 years old and only had insulation in the roof – nothing in the walls or under the raised timber floor. Towards the end of winter 2011, I crawled under my house and installed batt insulation as I was tired of having cold timber floors in the living areas. Prior to this, during winter 2011, my family and I were running the central heating at approx 24-25 degrees and wearing nothing less than a thick jumper, long pants and ugg boots to combat the cold coming up through the floors. The thermo cline throughout the house due to the cold under the house was nothing I had ever experienced before. Our feet were ALWAYS cold and our heating bill alone was well over $1200 per quarter as it was almost running constantly to try and maintain a comfortable temperature Winter 2012, the batts I spent a painful 8 hours installing made absolutely no difference. They were R2.5 batts, installed correctly as per manufacturer instructions. So I looked for a proper alternative. Having watched a number of (don't laugh) Holmes on Homes shows on foxtel, I was interested in the spray foam he used in a number of renovation projects and couldn't speak highly enough of… this led me to You Tube and then to Eco Foam… I have since had under my floors and external walls sprayed with foam and the difference is absolutely amazing ! we now run the heating at 19 degrees and it does not come on very often to maintain the warmth.
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Navid Naderi writes derivative poems and studies literature. He has worked on the history of philology in the 19th century, and contemporary American and Iranian poetry. Studio 51 is a collaborative project of Bahar Samadi and Navid Salajegheh since 2014. Their work consists of constructing a series of micronarratives and assemblages which reappear in a here and now that is alternative to the primary time and space of the used material. They recycle and re-employ pre-existing footages and other visual and textual materials, processing them through diverse media, spanning from moving images to performance, installation, and painting. The outputs of these projects are visual, auditory or tactile experiments which create new relations between content and expression of materials. Studio 51 also functions as a laboratory for these two artists to discover new forms for the possibilities of "working together" and, ultimately, to observe the way they evolve from one project to another. Pooyan Hashemi Tari has been engaged with various mediums such as painting, sculpture, installation, video art and performance. His works are 'self-processes' aiming to evoke questions in order to reexamine our understanding of the 'self'. He considers this process to be successful if it could preserve the complexity of the very general yet ambiguous question of 'who I am.' Central to the idea of self-process is the interrogation, and perhaps even transformation, of the innate or acquired thresholds, which, unbeknownst to us, have already formed the internal and external boundaries of our conception of the self.
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706: // Grab all of the user fields that need to be joined. Make sure you followed all the steps in the readme. Do you receive this error if you disable the plugin? I don't see any reference to the sphinx plugin in that trace. The plugin does however override the default class.searchmodel.php, which is where I would think the problem would be if the SQL was changed between v2.0 and v2.1. I didn't see any problems with my install of 2.1, but that was a few months ago and things may have changed since then. IT seems that @peregrine has reproduced this error in the past, so somethin must be wrong in the plugin somewhere for v2.1...I'll take a look. it happened with a beta version for me. for me, I installed vanilla 2.1, and the latest sphinxsearch, and didn't get the problem again, without necessitating change you suggested. not sure what factors made it go away. I did uninstall the Sphinx plugin and made a custom search plugin with searching by category and some other adjustments from standard search engine. I will mirror my installation on a developement machine and retry Sphinx with the fix you suggested in the next few days. I believe I figured out the problem. try removing $Configuration['Debug'] = TRUE; from your config.php if you have the error. and if I remove debug statement sphinx works fine. I also see this on my production site. Enabling debug via conf will throw errors on many pages in 2.1. Goes away when removing debug mode. another side issue if you have eventi plugin enabled, you won't be able to enable plugins via dashbpard either. * Override the default search from running right here! if(true) // Force this to be true while the sphinxsearch plugin is enabled! I can confirm that $Configuration['Debug'] = FALSE; solves the issue here.
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/ Investigation Orb, dust, bicycles, people and porta-potties at Burning Man 2018. © Caroline Brun Orb, dust, bicycles, people and porta-potties at Burning Man 2018. © Caroline Brun Burning Man 2019: Radical rehearsal for an uncertain future Published 19 May 2019 by Cherise Fong This year, the radically self-reliant Black Rock City in the Nevada desert will face a new challenge: top-down, tone-deaf intervention. Yet, passion still prevails in the voices of Burning Man past and present. "Imagine you are put upon a desert plain, a space which is so vast and blank that only your initiative can make of it a place. Imagine it is swept by fearsome winds and scorching temperatures, and only by your effort can you make of it a home. Imagine you're surrounded by thousands of other people, that together you form a city, and that within this teeming city there is nothing that's for sale." These words were spoken by Larry Harvey, the founder of Burning Man who passed away last spring, "Chief Philosophical Officer" and author of the famous 10 Principles, which serve to define the spirit of the Black Rock community to this day. Michael Benisty's "Love and Unity" surrounded by members of the FAFA theme camp in 2018. © Jane Hu For the past 28 years, the ephemeral Black Rock City has been a microcosm of what's possible when a bunch of creative humans commit to surviving together in the middle of nowhere, if only for a week. For the most part, it has been successful. For better or for worse, it has radically included an increasing number of newbies, nuclear families, Silicon Valley millionaires, turnkey trailer fashionistas and jetsetting celebrities. And the city's population (featuring an especially high percentage of educated thirtysomethings from California) has grown exponentially, from 4,000 in 1995 to 35,000 in 2005 to 70,000 since 2013, plus thousands of staff and volunteers—all reunited in a remote desert for a dedicated experimental spell of making and sharing. In a way, Burning Man is the original, if not the most extreme, "feral lab" on our planet. Bring Your Own Burn Massimo Priviero's first and only "burn" was in 2012, as a 30-year-old art student in San Francisco. A mutual friend had introduced him to the local Macchiarini jewellers, who were preparing their annual Dragon Smelter sculpture for Burning Man. As it turned out, they had an extra ticket, and they could use some help on the playa from someone who knew their way around a furnace. Massimo was already studying bronze sculpture in a foundry. He spent the next two months preparing for his nine days in the desert. "I was so excited when I got there, I spent the first three days awake," he says. He remembers the dust, the goggles, the boots, the sunscreen, the little gas stove, the sleeping bags, the tent, the violent winds and the life-saving water canteen. A whiteout sandstorm where you could barely see 3 meters in front of you. Waking up in the quiet morning to find everything white, covered in dust. Walking out into the deep playa and watching the sunrise with his girlfriend. Wearing a swimsuit by day, a fur coat by night. Rocks that would crack during the day, and shrink back at night. "That's the beauty—when you get to Burning Man you leave everything behind, there's nothing. For some people it may be scary, for some inspiring, comforting, it depends. I found it very nice. In the city you're surrounded by a concrete jungle all the time, then you get out there and you see the actual sunset on the horizon." Daniel Macchiarini's Dragon Smelter sculpture behind the crew (Massimo with goggles on forehead) at Burning Man 2012. © Macchiarini Creative Design Working on the dragon was fun too, he says. Covered in scales made from recycled steel, the 7-meter-tall fire-breathing sculpture housed in its belly a furnace that melted down empty aluminum cans collected on site. Massimo was in charge of pouring the liquid metal into a mold to create sheets, from which they punched out commemorative coins, based on that year's theme of Fertility 2.0. "I liked the concept of leave everything behind, and then leave no trace," Massimo continues. "I liked the giveaway thing, the camps, so many teams, crews, families coming together, the positive energy going around and getting to know people. What I didn't like was that somehow, the event is supposed to make you think about how fortunate you are, how very little you need in life to be happy. Seeing people getting there with big trailers, turnkey camps, fancy dresses, something that doesn't really belong, kind of ruins it." "Commodification"—in the form of purchasable, pre-packaged, all-comfort VIP getaways or celebrity fashion shoots with hired sherpas and wifi access, for example—is an ongoing, if not increasing, problem in Black Rock City. But it's certainly one, among others, that the nonprofit Burning Man organization has been making conscientious efforts to extinguish. Burning Man's Black Rock City seen from a plane in 2012. © Steve Juverson CC-BY 2.0 FAFA Mama Berta Hodges, a.k.a. Mama Bear, 58, first made the trek from her home in Sonoma, California, to the Black Rock Desert in 2011, after her oldest son and his two French pals decided to bring les mamans to Burning Man. Every year since then, she has returned to the playa, together with her husband and their sons. Berta now co-organizes the full-blown FAFA (Fucking Awesome French and Americans) theme camp, complete with 4 carports, 35 bicycles and 130 square meters of shade, which this year is hosted by 49 people from the USA, France, Morocco, Spain, Germany, UK and Canada. "Who we are, is just very Hospitable. I consider that to be very French, very European, more than American," says Berta. "Come on over—we have a front porch, have some tea, have a glass of wine, get out of the sun, come sit with us." FAFA camp's past "interactivities" have included pole dancing lessons, '70s disco dance party, plaster mask-making, lighted labyrinth, glow-in-the-dark bocce ball, scaffolding art pieces, jellyfish drone, Moroccan tea ceremony, Muay Thai Monday with hula by Germans, Korean snail goo face mask mini spa, DIY remote-controlled Pony Expresso… and "show your pecker (or your peaches) for a pickle". Berta Hodges, a.k.a. Mama Bear, outside FAFA camp on Tutu Tuesday. © FAFA Mamoun Ghallab, a.k.a. Zbilo, is a FAFA camp member since 2017 and the "zero-waste" founder of Zero Zbel in Morocco. Two years ago, he gave an energizing talk about how every individual can make meaningful choices to manage their consumption and waste more efficiently—even in Morocco, which has no official recycling infrastructure. This year, Mamoun will lead FAFA's own "leave no trace" effort. Rumble on the Playa This year, after 28 years of learning and fine-tuning through both careful planning and trial and error how to build respectful community and safe infrastructure within Black Rock City, Burning Man now faces a new threat from without. More specifically, from its landlord: the U.S. Bureau of Land Management (BLM), which is the federal agency that administers public land, including the Black Rock Desert. When the nonprofit Burning Man organization applied to renew its lease of the 14.5km2 pentagonal playa, the BLM retorted with a draft Environmental Impact Statement (EIS) recommending "requirements [that] would fundamentally change the operational integrity and cultural fabric of Black Rock City, and would spell the end of the event as we know it", according to the Burning Man Project. FAFA's always hospitable front porch. © FAFA Mandated "mitigations" to the ephemeral Black Rock City's environmental impact, according to the EIS, include replacing the city's temporary 14.5km-perimeter fence with a physical barrier, installing and maintaining dumpsters, imposing third-party searches of all vehicles and persons upon entry, monitoring illegal substance activity, shielding lights, reducing dust(!), "restoring playa contours"… Vague, overreaching or simply unnecessary, given Burning Man's proven track record of dealing with such issues more or less effectively and independently, the EIS recommendations fail to acknowledge the tireless efforts of Black Rock City's dedicated Department of Public Works (DPW), a workforce of several hundred individuals who work in the desert 4 months out of the year planning, surveying, building and deconstructing the basic infrastructure of the city (installing the perimeter trash fence, building the power grid, airport, shade structures, watering down roads, managing fuel services, potable and grey water, porta-potties… and even public bicycles). Furthermore, according to the Burning Man organization, barriers, dumpsters and searches in particular would all require significantly increased CO2-emitting transport and logistics, not to mention wasted time and prohibitive costs for burners and the organization, which already cooperates with BLM rangers patrolling the playa. FAFA's own art car, a.k.a. Funky the Psychedelephant. © FAFA Meanwhile, the tone-deaf authors of the EIS evoke the risk of civil unrest. In the spirit of Radical Self-Expression, and because citizen feedback also happens to be a legal part of the process, the Burning Man Project invited all burners to submit substantive comments on the BLM's draft EIS by April 29, 2019. Berta and her husband were among many burners who submitted their own letter to the Burning Man organization's carefully researched response. "Burning Man is taking a very professional approach," she says. "The government's approach is like with a lot of other things at this time due to the current leadership. Every year, the Department of the Interior tries to throw a wrench in it. Many of the allegations—light pollution, dust pollution—are ridiculous. A lot of it is not based on any fact. Burning Man has already mitigated many of these things to a higher degree than what is recommended by other agencies. If you think about what would happen in a regular city of 100,000 people in a period of 7 days, it would be a lot worse." Mind over MOOP No doubt the most famous and most emulated of Burning Man's 10 Principles is Leave No Trace. While the concept of garbage itself may be a myth, the removal of any and all MOOP (Matter Out Of Place) is taken very seriously, especially by the Department of Public Works' dedicated task force. MOOP may range from cigarette butts to plastic glitter to grey water to pieces of wood (most common). Of course, there are always a few bad burners who bring in illegal fireworks and neglect to clean up the ashes, throw their garbage bags out the window onto the side of the road, or are just sloppy about picking up and packing out. And the Burning Man organization does not hesitate to disinvite such repeat offenders. The annual MOOP Map, created by the DPW's Playa Restoration crew—some 125 volunteers and workers who remain on the playa two weeks after the event has concluded to finish up sweeping across the playa with fine-toothed rakes—identifies very specific locations (and camps) where the Resto crew's final "mooping" was easy, moderate or difficult. MOOP Map 2018. © Burning Man Project Every year since 1999, the BLM has imposed a Post-Event Site Inspection of the playa, which allows for no more than 1 square foot of MOOP per acre—in other words, no more than 0.002% of MOOP for the entire 3603 acres of Black Rock City. And every year since the inspection was introduced, Burning Man has passed. This near-impossible achievement has resulted from the active participation of all burners, in the spirit of Radical Self-Reliance and Civic Responsibility. Imagine a true Fab City in the making, dismantled and deconstructed. As Dominic Tinio, a.k.a. D.A., Burning Man's Playa Restoration Manager since 2005, writes: "Our Leaving No Trace principle is just the beginning, one small step toward a sustainable future. Because Burning Man is not a place. Burning Man is a culture, and we are worldwide." Inner suns Nathan Altman, a.k.a. Mary Poppins, so-nicknamed after he originally volunteered to help build a small part of an art piece in 2015, having never been to Burning Man before, and ended up leading the build of the Temple. The following year, he was invited back to Black Rock City as the construction and utility superintendent of the Department of Public Works. And he has returned to the playa every year since. After designing and leading the build of the Man with Larry Harvey in 2017, running for the U.S. Senate and participating in Burning Man as a volunteer in 2018, this year Nathan aims to bring a new art piece to the playa, on a monumental scale: The Inner Sun. Illustration of "The Inner Sun" art project. © The Inner Sun "For the past few years I've been trying to find ways to spread this beyond just one main event," says Nathan. "The organization has done as well with regional networks and groups. The important part is that it inspires people to be their best selves, to try things, to experiment, to think differently. We need more of that in the world." Brains on fire As the majority of burners come from California, where deadly and destructive wildfires have become an increasingly common occurrence, in addition to causing unprecendented air pollution across the state, it may also be time to weigh both the artistic and environmental impacts of Black Rock bonfires. From her Sonoma home, Berta recalls: "Last year with my middle son, we said we have a different relationship with fire now. Our house didn't burn, but we had to be evacuated from it. We live in an area of catastrophic fires two years ago. Honestly, I'm very conflicted about the celebratory nature of fire, but this is something very paganistic. Humans through the ages danced around fires, but for us it's become more of a symbol of destruction in many ways." FAFA on the playa. © FAFA Which brings us back to the theme of Burning Man 2019—Metamorphoses: "This year's theme is a celebration of change, and an exploration of uncertainty. As such it invites a consideration of time; not its circular nature, or its attendant ritual, but in this case the relentless flight of time's arrow, and an embrace of the elusive now. Memory is fickle, and the future is uncertain." More information on Burning Man Also on Makery: Burning Man: In the beginning, there were makers (2016)
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Over the course of five days in Egypt, the Lines & Spaces delegation worked directly with over 150 Egyptian students, educators, journalists, and writers in the cities of Cairo and Luxor. They held workshops and panel discussions at Ain Shams University, South Valley University, and the American University of Cairo. A special highlight was the chance to reconnect with IWP alumni from the IWP Fall Residency and Between the Lines programs. A special Lines & Spaces tour was added to the 2018 schedule thanks to a special project with the ECA Collaboratory and the U.S. Embassy in Asmara, Eritrea. The delegation traveling to Egypt extended their trip to travel south to Asmara for a three-day introductory workshop with local writers. Topics covered in the first three days included poetry, fiction, and literary translation. While most of the group departed after the initial workshop, Caite Dolan-Leach remained in Asmara to take the workshop beyond the surface with two additional weeks of meetings focused on workshopping the participants' original materials. Zaina Arafat, a Palestinian-American writer, has had stories and essays appear in The New York Times, Granta, The Believer, Virginia Quarterly Review, The Washington Post, The Atlantic, The Christian Science Monitor, BuzzFeed, VICE, NPR, and elsewhere. A novel and an essay collection are forthcoming. A recipient of the 2018 Arab Women/Migrants from the Middle East fellowship, she was also a Muslim Communities coordinator at the Asian American Writers Workshop, where she curated a portfolio of work responding to the travel ban. She holds an M.A. in international affairs from Columbia University and an M.F.A. from Iowa. She lives in Brooklyn. Caite Dolan-Leach is the author of Dead Letters (2017), and We Went to the Woods (2019), and the co-translator of two novels, Orphans and Newspaper, from French. Her work has appeared in The Paris Review, Nylon, Music and Literature and The Quarterly Conversation; her novel has been a Book of the Month Book of the Year nominee, a Publisher's Weekly Writers to Watch selection, and translated into four languages. A graduate of Trinity College Dublin and holding a MA in Cultural Translation from the American University of Paris, Caite lives in Iowa City.
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At the Waldorf, "Catholic Thanksgiving" – On the Night That Smith Built, Dolan and Colbert's Round Two In an exceptional return of the favor he gave last month – namely, sharing one of TV's most coveted audiences with the USCCB President and Cardinal-Archbishop of New York – tonight saw Stephen Colbert flank Tim Dolan on the dais of the Waldorf-Astoria as the Comedy Central icon stepped into American Catholicism's most legendary speaking slot... at least, the sole Big Turn allowed the laity: the keynote address of the Al Smith Dinner. Marking this Third Thursday of October's 68th annual tribute to the first American Catholic to be nominated for the Presidency, a top-shelf fundraiser for Gotham's mother-chapter of Catholic Charities – and, for a half-century, an all-around institution of American political culture – the choice of an actual comic (however famously devout) to headline the white-tie, big-money jokefest was a considerable departure from the long line of statesmen, journalists or titans of industry tasked with the talk in the "off years" when both Presidential nominees aren't in attendance for what's traditionally become their lone joint appearance beyond the debates. Then again, in these final days of a three-year stewardship of the Stateside Bench which has brought epochal rounds of triumph and turbulence alike, as The Tim prepares to depart the Mothership's hot seat and return to his cherished spot at the back of the Floor – in Dolan-logic, a place close by both the coffee and the can – His Eminence's remarkably simpatico tag-team with the Charleston-bred improv guy who, for the first time, swept this year's Emmys for late-night comedy has made for an especially fitting high note on which to go out... and, arguably, a note that only the last student of John Tracy Ellis ever could've hit. Amid the very new and different circumstance of a Vatican keen to carve out a more substantive role for episcopal conferences than they've ever known – for the first time, remember, a onetime Bench-chief is now The Pope – the next USCCB president and vice-president will be elected at the body's Fall Plenary in Baltimore, which opens on November 11th. Should precedent hold, the ten-man slate of contenders will be revealed by month's end. For now, much as the evening's keynoter embarrassingly bungled his pronunciation of terms like "chasuble" and "Humanae Vitae" – all while re-declaring himself "America's Most Famous Catholic" – here's fullaudio of Colbert's raucous witness and Dolan's atypical straight-man close before the Midtown power crowd, all of which aired live over SiriusXM Radio's The Catholic Channel, the 1011-run satellite outlet whose lineup is led by the cardinal's live weekly call-in show.... Especially given all the "expertise"-that-isn't which suddenly abounds these days, as context goes, it bears reminding that, from his first Smith Dinner as a cardinal (fullvid), Dolan had already ditched the custom of his predecessors by not donning the scarlet ferriaolo on the dais, even with Barack Obama and Mitt Romney both at his side, and the international press corps swarming all around. All that said, at the heart of things, it was announced at the night's start that the dinner had raised over $3 million for the Big Apple's Catholic Charities – the dinner's biggest draw ever for an Al Smith at which the White House wasn't at stake. posted by Rocco Palmo at 22:39 Name: Rocco Palmo Live from the Whispers Wire.... Live from Page Three "Guitar case" + reader support = the only way these pages survive.... Thoughts for the author? E.mail him: [email protected] A Lenten Road Trip – For the Curia, There Goes the... Palace Notes: Already, Parolin's Under the Knife..... The Great "Untier" – For Francis, There's Somethin... "Service, Yes – Servitude, No!": "Woman's Day," Fr... "Mother, Together We Will Fight... Together We Wil... The Council's Day... St John's Day At Supremes' Mass, A Call To Civility and Communit... "Francis, Go and Rebuild My House" Live from Assisi "Francis, Teach Us to Remain Before the Cross... T...
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Q: The code is for downloading excel file(.xls) Problem: After download, the file doesn't contain the data. i.e it become blank. So please help me for this. <?php session_start(); include_once 'oesdb.php'; $id=$_REQUEST['id']; if(isset($_REQUEST['id'])) { $sql=executeQuery("SELECT * FROM file where id=$id"); $rows = mysql_fetch_array($sql); $file =$rows['file']; header('Content-Description: File Transfer'); header('Content-Type: application/vnd.ms-excel'); header('Content-Disposition: attachment; filename='.basename($file)); header('Content-Transfer-Encoding: binary'); header('Expires: 0'); header('Cache-Control: must-revalidate'); header('Pragma: public'); header('Content-Length: ' . filesize($file)); ob_clean(); flush(); readfile('uploads/'.$file); exit; } ?> A: Why not create a HTACCESS file in uploads folder then states Allow From 127.0.0.1 Deny From All Then just create a URL, use HTML5's new download feature, do something like this: <a href="uploads/filenamehere.txt" download="filenamehere.txt">click to download</a> It saves time trying to use PHP to make a download script. A: try replacing this: $file =$rows['file']; by this: $file = "uploads/".$rows['file']; and this: readfile('uploads/'.$file); by this readfile($file); if still not working put the value returned by the readfile function IMPORTANT Please take in consideration the sql injection issues (see comment of Ondřej Mirtes) A: The problem is here: header('Content-Length: ' . filesize($file)); Content-Length receives zero value and browser downloads zero-length file, as you told him. If $file is path relative to upload/, you should do this: header('Content-Length: ' . filesize('upload/'.$file)); Be sure that filezise() returns correct size and readfile() realy outputs it. But the other problem is that you mentioned UPLOAD folder and using uploads. They are not same and case is important. Also, may be using relative paths in 'uploads/'.$file is not a good idea, it is better to use absolute path. For example, '/var/www/upload/'.$file.
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Just realised I've neglected my blog for a while and it's feeling a little sorry for itself. So here's a quick update on progress on the novel. 4th Edit/Rewrite After having some amazing feedback from my BETA readers, I've decided that I need to take a more severe hatchet strike to my manuscript. It was apparent that some things weren't clear to the reader, some of the dialog needed revisiting and some of the plot needed ... adjustments ("The Plot Adjustment Bureau", sounds like a Jasper Fforde novel!). Having this as my first exposure to writing and polishing a manuscript has been a struggle to be honest. Don't get me wrong, I'm loving the learning curve, but it has made me think about how I write. Finding time has been a bit of a problem recently, what with two demanding kids and a busy family life, but that's just an excuse really. Aren't they all?
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This post is called Big Suvs. You can download all the image about Big Suvs for free. Below are the image gallery of Big Suvs, if you want the image or such as this post please contribute with us to share this post to your social advertising or save this post in your device.
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Multiple interventions improve analgesic treatment of supracondylar fractures in a pediatric emergency department Porter, Robert Neil and Chafe, Roger and Newhook, Leigh A. and Murnaghan, Kyle D. (2015) Multiple interventions improve analgesic treatment of supracondylar fractures in a pediatric emergency department. Pain Research and Management, 20 (4). pp. 173-178. ISSN 1918-1523 [English] PDF - Published Version Available under License Creative Commons Attribution Non-commercial. Official URL: http://dx.doi.org/10.1155/2015/970683 BACKGROUND: Provision of appropriate and timely treatment for pain in the pediatric population has been challenging. Children with painful conditions commonly present to emergency departments (EDs), a setting in which it may be particularly difficult to consistently provide timely analgesic interventions. OBJECTIVES: To measure the effectiveness of a set of interventions in improving the rate and timeliness of analgesic medication administration, as well as appropriate backslab immobilization (application of a moldable plaster or fiberglass splint), in a pediatric ED. METHODS: Data regarding pain management were collected on a consecutive sample of cases of supracondylar fracture over a 13-month period. This followed the implementation of a formal triage pain assessment and treatment medical directive, supplemented with relevant education of nursing and house staff, and posters in the ED. These data were compared with data previously collected from a similar cohort of cases, which presented before the interventions. RESULTS: Postintervention, the proportion of patients treated with an analgesic within 60 min of triage increased from 15% to 54% (P<0.001), and the median time to administration of an analgesic decreased from 72.5 min to 11 min (P<0.001). Rates for backslab application before radiography were similar before and after the intervention (29% and 33%, respectively; P=0.646). CONCLUSIONS: A multifaceted approach to improving early analgesic interventions was associated with considerably improved rates of early analgesic treatments for supracondylar fracture; however, no improvement in early immobilization was observed. Memorial University Open Access Author's Fund Analgesics, Emergency, Orthopedic Medicine, Faculty of
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Essar on a mission to grow dealer network By Merril Boulton 2019-03-08T00:00:00+00:00 Essar Oil (UK) has restated its aim of 400 sites within the next five years, following the appointment of Ramsay MacDonald as head of retail at the start of the year. "We've got fuel quality, we've got scale, we've got the ambition, the image, the team," said MacDonald. "It's not a big leap of faith, it's just the need to build that credibility and reassurance to the dealer community." A year after leaving the retail helm at Certas Energy, Ramsay MacDonald is back in the saddle, refreshed and rejuvenated, and greatly enthused about his new role at Essar. "What excited me about coming to Essar was the people, the product, and the project here," explained MacDonald. "I love this industry – I still think I've got a lot to offer. It's great being involved in the management of a complicated, large energy plant – the Stanlow Manufacturing Complex. The brand really appealed to me as well – it has a lot of scope. "The retail team I work with are very engaging, committed people. We can build a great brand and some really good partnerships with suppliers and dealers – and being the principal sponsor of the Forecourt Trader Awards for 2019 adds into that." Essar has been very open about its ambitious plans for the UK, and the oft-quoted goal of getting to 400 sites as quickly as possible. It's a realistic and necessary target for a UK refiner, according to MacDonald: "If you put it into context, looking at what other refiners have in the UK, it's about getting that criticality. I don't see why we shouldn't be as big as Jet, for example, in five years. If we can get more than that, even better. It's about facilitating the profile of the brand and a long-term supply position. We export a proportion of our production here. But the economics dictate to us that it's far better if we can sell it inland. So that's why the strategic position of us getting into retail makes perfect sense." Encouraging dealers to change fuel brand is no easy feat, but MacDonald is confident there is plenty in the Essar armoury to persuade them, not least the fact it is a UK-based manufacturer with significant ongoing investment in the market; but also highlights the company's fuel products, which it will certainly be shouting more about in the future, with the suggestion of a premium fuel product launch later in the year. It produces more than 16% of the UK's transport fuels, but is also looking to the future in terms of environmental developments. "We're very proud of our product provenance and product quality," stresses MacDonald. "The fact we are a manufacturer – we import, we export, we create products here. As the industry goes into this changing environment, who better to steward customers through that transition than someone who is actively involved in all aspects of the supply chain?" However, like certain other oil companies, Essar is also on the lookout for acquisitions. It already has plans underway for a company-owned flagship store at Elton Green, opposite the Stanlow Refinery, on a run-down site on the busy A5117. "We're very excited about Elton Green, because we think it will give us a good insight into what model would be right for us. We've got no desire to operate the sites ourselves. So we would be looking at retailer partnerships to do the final execution – it's such a specialist area in itself. "But acquisition, and getting into that as an alternate model would make perfect sense for us. So we're certainly interested in looking at anything on that front as long as the numbers add up. You also have to look at what greenfield opportunities there are as well. But, of course, at the other end of the scale you've got the unmanned model. Asda and others have proved that can be viable. We could have a mix of all those formats."
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Found 124 items (-) Remove Alumni filter Alumni Dan Adler '07 brings innovation, Yale-honed singing skills to science class In 2012, Boston magazine published a feature story called "Lawrence, MA: City of the Damned." It chronicled the many woes of the state's poorest city – a mayor under investigation, a steep rise in crime, rampant drugs, and a school system that had been... 1st Generation Yale Conference to highlight alumni and faculty trailblazers As a Yale freshman, Peggy Kuo ('85 B.A.) remembers being struck by the financial comfort of many of her peers — how easily they had transitioned to this collegiate world via the prep school track. "Yale was a big departure from the world I had come from... Startup Yale showcases a more inclusive vision of entrepreneurship Startup Yale, which began as a combined effort among a number of campus organizations to raise awareness of entrepreneurship has grown into something much larger. The now week-long series — happening April 16-20 at Yale School of Management and other... A recent first-generation Yalie on aiming for the stars Leobardo Espinoza Jr. ('17 B.A.) was one of just a handful of students selected by The New York Times in 2013 to blog about his experience applying to colleges. In the series, he wonders about whether to take a gap year to study abroad, writes of his... Yale Alumni Service Corps strengthens global ties, and adds faculty A planned trip this summer to Cape Town, South Africa, will mark the first time in the Yale Alumni Service Corps' (YASC) decade-long history that Yale faculty have accompanied the volunteers to a program in Africa. It's an important milestone, says Joao... Global alumni to elect next representative to the Yale board of trustees Two alumni are on the ballot of this year's Alumni Fellow Election, which will determine the next alumni fellow of the Yale board of trustees, known formally as the Yale Corporation. Voting opened on April 11 to eligible alumni around the world. The... Yale Blue Green connects alumni with environmental interests From Yale to New York buzz — an innovative opera company on the rise Ethan Heard '07 B.A., '13 M.F.A. is not afraid of risks. He and other alumni collaborators have been igniting audiences with intimate, modern-day interpretations of opera classics in New York City as part of Heartbeat Opera. The company brought "Madame... Alumni lead the way in supporting diversity, equity, and inclusion In February 2016, the Association of Yale Alumni (AYA) Board of Governors appointed the Yale Alumni Task Force on Diversity, Equity, and Inclusion (DEI) to better understand how alumni could be more effective in promoting DEI across all activities. But... Newborns in Need honors nursing professor who helped countless women Many Yale students have stories about the professors who inspired them, but few can say that they were at her bedside after she'd given birth, providing postpartum care. Such is the singular life of nursing students. Heather Reynolds '80 M.S.N., lecturer... Brita Belli (58) Apply Brita Belli filter Susan Gonzalez (4) Apply Susan Gonzalez filter E.J. Crawford (2) Apply E.J. Crawford filter LuAnn Bishop (2) Apply LuAnn Bishop filter Adam Gaber (1) Apply Adam Gaber filter Anita Norman (1) Apply Anita Norman filter Bess Connolly (1) Apply Bess Connolly filter Hope McGrath (1) Apply Hope McGrath filter Matthew Woodard (1) Apply Matthew Woodard filter Patrick C. O'Brien (1) Apply Patrick C. O'Brien filter William Weir (1) Apply William Weir filter Remove Alumni filter Alumni Remove Community filter Community Campus (64) Apply Campus filter FAS (6) Apply FAS filter
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All pre-season orders are due April 26th, and will be ready mid May! Pick up available in River Falls or Prescott. Please clarify in the notes where you would like it picked up. Shipping is also an option for an additional fee.
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Home Main Menu Campus/Local Wayne Sullivan to Retire; Search Underway for Next Campus Safety Director Wayne Sullivan to Retire; Search Underway for Next Campus Safety Director Longtime Campus Safety director to retire after nearly two decades at UC. Photo by Samuel Northrup Samuel Northrup, Editor-In-Chief After nearly two decades at Utica College, Director of Campus Safety Wayne Sullivan will be retiring on Aug. 31. Prior to UC, Sullivan worked at Prudential Financial as a principal investigator for 23 years, primarily serving as a watchdog over insurance transactions between the company and its clients in the central New York area. He then opted for an early retirement from Prudential before deciding to take a position with the Office of Campus Safety. While Sullivan never held a formal law enforcement position before, he was hired as a night sergeant by Campus Safety. He explained his previous job taught him important skills, including how to conduct criminal investigations and "read people." Sullivan was quickly promoted to a captain's position, which he held for nine years, before being promoted to director of Campus Safety in 2011. "It's been very educational [working at Utica College]," Sullivan said. "The part I love most about it is watching young people come in, not really knowing what they want and stumbling along the way, [but then seeing them grow as individuals]." Throughout his tenure at UC, Sullivan said he has "seen a lot of things" and presided over several major safety events — chief among them was last year's lockdown, which started after Campus Safety received anonymous threats that someone was armed with a gun inside Gordon Science Center. Without any weapons, Sullivan and another officer rushed to the academic buildings on March 5, 2018, without any concern for who was waiting in the academic buildings and whether or not they were actually armed. "If it happened again today, we'd probably do the same thing," Sullivan said. While ensuring safety on campus has been his top priority as director of Campus Safety, Sullivan said it has been "the little things," such as helping students, that have made the job worth it to him. "We have very good, respectable people who come here and grow up to become our future — that's what makes everything shine for me," he said. As Sullivan completes his final four months on the job, a small committee led by Director of Emergency Management Shad Crowe has already begun searching for Utica College's next Campus Safety director. The seven people comprising the Campus Safety director search committee include members of each major constituency at UC. By involving students, faculty and staff, Crowe said he is hoping to ensure that each group receives equal representation and input during the candidate interview process. "I'm hearing a lot of great ideas about what we can do to improve the things that go on in within this office (Campus Safety)," Crowe said. But beyond just experience in safety and higher education, Crowe explained UC's next Campus Safety director must have an ability to connect and relate with UC's diverse student body. Establishing relationships with students is reflected in the position's list of required skills, he said, and will be a crucial part of the next director's job — especially in the aftermath of last month's confrontation between students and Campus Safety officers during an emergency situation in Strebel. Since the incident, students have voiced concerns over inconsistent and racially biased policing practices by Campus Safety officers. "Diversity and inclusion training, experience with other cultures and races, is so important for this candidate," Crowe said. "We've got some wounds and we need to pay attention to them and do some real work to help heal." According to the job requirements posted on UC's hiring portal, candidates for Campus Safety director must demonstrate the following: (1) a record of diversity and inclusion training; (2) a commitment to "delivering safety services in an equitable, cooperative and inclusive manner" within a diverse community; (3) an ability to effectively work with "diverse communities and the broadest range of constituents on campus." Sophomore Michenelle Delille, who witnessed the March 1 Strebel incident, is the student representative on the Campus Safety director search committee. Delille explained that the ideal candidate for the position should be able to navigate high-pressure safety situations but also have the ability to connect with students so that they feel more comfortable with Campus Safety — which starts by being "genuine and nice." "There are Campus Safety officers who will walk by and it kind of seems like they are above us," Delille said. "They do have more authority than us, but at the end of the day, we're all human beings. They just kind of have a cocky attitude, and that creates a gap because it makes it seem like they think they're above talking to us." In her role as a committee member, Delille has been focused on talking to students from different backgrounds about what attributes they want to see in UC's next director of Campus Safety. With all the feedback that her and members of the committee have gathered, she is confident that UC is taking "everything into consideration," including the concerns of minority students. "For some of us, this is our home away from home, so we need to feel comfortable in the environment we're going to be [living in] for a long time," she said. "[The community] needs to feel comfortable that Campus Safety knows the job that they have to get done." Crowe said that the committee is close to making a shortlist of candidates from the approximately 15 applicants who have interviewed. Once the list is formed, the remaining candidates will be invited to campus to participate in open forums with students. The forums, Crowe confirmed, will most likely take place from May 1-3 and give students an opportunity to ask candidates any questions they want. "I don't think they (candidates for the director position) are going to have a choice but to answer those tough questions [about race relations]," Crowe said. "And they are tough, but I fully expect candidates to be prepared for them. These are tough times, but we need to grind our way through these difficult questions. Are we ever going to answer them fully? Probably not, but we have to try and do something to improve our relations across all cultures on this campus." Previous articleOp-Ed: A Message on Diversity and Race Relations from Kendal Santiago Next articleNACCC Survey to Evaluate Racial Climate on Campus
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by Michael McLaughlin August 30, 2019 This week's list of data news highlights covers August 24-30, 2019, and includes articles about AI translating Lego instructions for blind individuals and an AI-enabled robot that can fly a plane. 1. Combating the Opioid Crisis with Data The U.S. Department of Justice is using data analytics to find doctors, nurses, and pharmacists who are illegally prescribing opioids. The department analyzes data from Medicare, Medicaid, the Centers for Disease Control and Prevention, and state pharmacy databases to identify individuals who may be overprescribing pills and uses traditional law-enforcement techniques, including undercover stings, to develop cases. Within months of using data analytics in the Appalachian region in early 2019, the DOJ indicted dozens of individuals illegally prescribing opioids. 2. Translating Lego Instructions for the Blind Lego and the Austrian Research Institute for AI are using AI to create Braille and audio building instructions for the visually impaired. The institute has developed AI software that can translate Lego's visual instructions to text, allowing for the creation of screen reader, Braille reader, and audio instructions. Lego is implementing the instructions for four building sets and tested their accuracy with children from the UK and Denmark. 3. Tracking Bird Migrations A group of researchers led by an individual from the University of Massachusetts, Amherst, have developed an AI tool that analyzes weather radar data to automatically track birds migrating at night. The researchers trained the system on radar scans from 2014 and 2016, teaching the system to differentiate between precipitation and birds. The researchers found that most bird migrations take place on a few select nights. 4. Creating a Robot to Pick Up Trash Researchers from Vishwakarma Government Engineering College in India have developed an AI-powered robot that can automatically detect and pick up trash. The robot uses a neural network to detect trash while another algorithm determines the best path for the robot to reach the object. The robot then uses a robotic arm to collect and drop the trash into a container attached to its body. 5. Finding Gender Bias in Literature Researchers from the University of Copenhagen and other universities have used machine learning to show gender bias in literature. The researchers used a machine learning model to analyze 3.5 million books published between 1900 and 2008, finding that authors most frequently described women in relation to their appearance while using behavioral descriptors for men, such as rational or brave. The researchers also found that authors are five times more likely to use negative words to describe a woman's appearance than a man's. 6. Building a Robot Pilot U.S. robot maker DZYNE Technologies has developed an AI-powered robot that passed the Federal Aviation Administration's test for piloting light aircraft. The robot uses computer vision to read dials and meters and robotic limbs to press the foot pedal and handle the control wheel. The robot can perform all aspects of a flight, such as taking off, following a flight plan, and landing, without human intervention. 7. Helping Veterans Transition to Civilian Life The U.S. Department of Veterans Affairs and IBM developed a mobile application that uses AI to support veterans' mental well-being and transitions to civilian life. The app assesses brain function and emotional health, including by detecting whether a veteran sounds different than usual when interacting with an AI-enabled chatbot. The app also uses AI to connect users to resources for their specific needs and identify jobs posts that align with their military skill sets. 8. Predicting Hate Crimes in the UK UK police are using a tool called the Online Hate Speech Dashboard that uses AI to analyze Twitter posts to predict spikes in Brexit-related hate crimes. The tool's algorithms detect speech that is Islamophobic, anti-Semitic, anti-LGTBQ, and directed against people from certain countries, and it analyzes between 500,000 and 800,000 Brexit-related tweets per day. Of those tweets, it identifies roughly 0.2 percent as hateful and uses tweets tagged with city locations to create a map of hate hotspots. Researchers have found that an increase in hate speech on Twitter correlates with increases in hate crimes against minorities in London. 9. Tracking Illegal Deforestation MapBiomas, a network of universities, technology firms, and non-government organizations, has developed a tool to track illegal deforestation in Brazil in near real-time. Brazil's Ministry of the Environment analyzes satellite images at a resolution of 30 meters to send alerts when it notices changes in forest cover, but the image resolution is not sharp enough to discern what is causing the potential deforestation. MapBiomas' tool automatically uses these alerts to analyze higher resolution satellite images and checks a property registry to determine if the possible deforestation is legal. During a test phase, the tool automatically produced 5,000 reports in two and a half months, which authorities can use to prosecute those engaging in illegal deforestation. 10. Measuring a Patient's Overall Health Researchers from the Mayo Clinic have developed a neural network that doctors could use to measure a patient's overall health. The researchers trained and tested the network on the electrocardiogram data of 775,000 patients, finding the network could predict gender and age with 90 percent and 72 percent accuracy, respectively. The discrepancy or similarity between patients' predicted and actual ages may serve as a measure of their physiological age, a measure of overall body functioning and health distinct from chronological age. The researchers found that individuals with significantly higher predicted than actual ages had experienced significant health problems, such as a heart attack, and people identified as younger had fewer health problems. Image: David McBee Michael McLaughlin Michael McLaughlin is a research analyst at the Center for Data Innovation. He researches and writes about a variety of issues related to information technology and Internet policy, including digital platforms, e-government, and artificial intelligence. Michael graduated from Wake Forest University, where he majored in Communication with Minors in Politics and International Affairs and Journalism. He received his Master's in Communication at Stanford University, specializing in Data Journalism. Improving the Ability of AI Systems to Recognize Human Emotion Visualizing Deforestation in Brazil
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Der Kreis Baktalórántháza (ungarisch Baktalórántházai járás) ist ein Binnenkreis im Zentrum des nordostungarischen Komitats Szabolcs-Szatmár-Bereg. Er grenzt an folgende sieben Kreise, beginnend im Westen im Uhrzeigersinn: Nyíregyháza, Kemecse, Kisvárda, Vásárosnamény, Mátészalka, Nyírbátor und Nagykálló. Geschichte Der Kreis ging zur ungarischen Verwaltungsreform Anfang 2013 aus 12 der 19 Gemeinden seines Vorgängers, dem gleichnamigen Kleingebiet (ungarisch Baktalórántházai kistérség), hervor. Sieben Gemeinden (mit 43,7 % der Fläche und 43,5 % der Bevölkerung) wurden an die umliegenden Kreise (Kemecse 2, Kisvárda 2, Nyíregyháza 1, Vásárosnamény 2) abgegeben. Gemeindeübersicht Der Kreis Baktalórántháza hat eine durchschnittliche Gemeindegröße von 1.607 Einwohnern auf einer Fläche von 21,21 Quadratkilometern. Die Bevölkerungsdichte liegt unter dem Komitatswert. Der Verwaltungssitz befindet sich in der einzigen Stadt, Baktalórántháza, im Osten des Kreises gelegen. Quellen PDF- und XLS-Dateien: Volkszählung 2011: 2013: ; 2016: Einzelnachweise Baktaloranthaza Komitat Szabolcs-Szatmár-Bereg
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package scopegraph import ( "fmt" "github.com/serulian/compiler/compilergraph" "github.com/serulian/compiler/graphs/scopegraph/proto" "github.com/serulian/compiler/graphs/typegraph" "github.com/serulian/compiler/sourceshape" ) var _ = fmt.Printf // scopeLambdaExpression scopes a lambda expression in the SRG. func (sb *scopeBuilder) scopeLambdaExpression(node compilergraph.GraphNode, context scopeContext) proto.ScopeInfo { if _, ok := node.TryGetNode(sourceshape.NodeLambdaExpressionBlock); ok { return sb.scopeFullLambaExpression(node, context) } return sb.scopeInlineLambaExpression(node, context) } // scopeFullLambaExpression scopes a fully defined lambda expression node in the SRG. func (sb *scopeBuilder) scopeFullLambaExpression(node compilergraph.GraphNode, context scopeContext) proto.ScopeInfo { var returnType = sb.sg.tdg.AnyTypeReference() // Check for a defined return type for the lambda expression. returnTypeNode, hasReturnType := node.TryGetNode(sourceshape.NodeLambdaExpressionReturnType) if hasReturnType { resolvedReturnType, rerr := sb.sg.ResolveSRGTypeRef(sb.sg.srg.GetTypeRef(returnTypeNode)) if rerr != nil { return newScope().Invalid().GetScope() } returnType = resolvedReturnType } var currentContext = context var parameterTypes = make([]typegraph.TypeReference, 0) pit := node.StartQuery(). Out(sourceshape.NodeLambdaExpressionParameter). BuildNodeIterator() for pit.Next() { parameterTypeNode, hasNodeType := pit.Node().TryGetNode(sourceshape.NodeParameterType) if !hasNodeType { return newScope().Invalid().GetScope() } parameterType, perr := sb.sg.ResolveSRGTypeRef(sb.sg.srg.GetTypeRef(parameterTypeNode)) if perr != nil { return newScope().Invalid().GetScope() } parameterTypes = append(parameterTypes, parameterType) currentContext = currentContext.withLocalNamed(pit.Node(), sb) } // Scope the block. If the function has no defined return type, we use the return type of the block. blockScope := sb.getScopeForPredicate(node, sourceshape.NodeLambdaExpressionBlock, currentContext.withImplemented(node)) if !hasReturnType && blockScope.GetIsValid() { returnType = blockScope.ReturnedTypeRef(sb.sg.tdg) } // Build the function type. var functionType = sb.sg.tdg.FunctionTypeReference(returnType) // Add the parameter types. for _, parameterType := range parameterTypes { functionType = functionType.WithParameter(parameterType) } return newScope().IsValid(blockScope.GetIsValid()).Resolving(functionType).GetScope() } // scopeInlineLambaExpression scopes an inline lambda expression node in the SRG. func (sb *scopeBuilder) scopeInlineLambaExpression(node compilergraph.GraphNode, context scopeContext) proto.ScopeInfo { var returnType = sb.sg.tdg.AnyTypeReference() var currentContext = context var parameterTypes = make([]typegraph.TypeReference, 0) pit := node.StartQuery(). Out(sourceshape.NodeLambdaExpressionInferredParameter). BuildNodeIterator() for pit.Next() { paramNode := pit.Node() currentContext = currentContext.withLocalNamed(paramNode, sb) // If there is an explicitly defined type on the parameter, we use that. definedTypeNode, hasDefinedType := paramNode.TryGetNode(sourceshape.NodeLambdaExpressionParameterExplicitType) if hasDefinedType { definedTypeRef, derr := sb.sg.ResolveSRGTypeRef(sb.sg.srg.GetTypeRef(definedTypeNode)) if derr != nil { return newScope().Invalid().GetScope() } parameterTypes = append(parameterTypes, definedTypeRef) continue } // Otherwise, check for an inferred parameter type. parameterType, hasParameterType := sb.inferredParameterTypes.Get(string(paramNode.NodeId)) if hasParameterType { parameterTypes = append(parameterTypes, parameterType.(typegraph.TypeReference)) } else { parameterTypes = append(parameterTypes, sb.sg.tdg.AnyTypeReference()) } } // Scope the lambda's internal expression. exprScope := sb.getScopeForPredicate(node, sourceshape.NodeLambdaExpressionChildExpr, currentContext) if exprScope.GetIsValid() { returnType = exprScope.ResolvedTypeRef(sb.sg.tdg) } // Build the function type. var functionType = sb.sg.tdg.FunctionTypeReference(returnType) // Add the parameter types. for _, parameterType := range parameterTypes { functionType = functionType.WithParameter(parameterType) } return newScope().IsValid(exprScope.GetIsValid()).Resolving(functionType).GetScope() } // inferLambdaParameterTypes performs type inference to determine the types of the parameters of the // given lambda expression (if necessary). // // Forms supported for inference: // // var someVar = (a, b) => someExpr // someVar(1, 2) // // var<function<void>(...)> = (a, b) => someExpr // // ((a, b) => someExpr)(1, 2) func (sb *scopeBuilder) inferLambdaParameterTypes(node compilergraph.GraphNode, context scopeContext) { // If the lambda has no inferred parameters, nothing more to do. if _, ok := node.TryGetNode(sourceshape.NodeLambdaExpressionInferredParameter); !ok { return } // Otherwise, collect the names and positions of the inferred parameters. pit := node.StartQuery(). Out(sourceshape.NodeLambdaExpressionInferredParameter). BuildNodeIterator() var inferenceParameters = make([]compilergraph.GraphNode, 0) for pit.Next() { inferenceParameters = append(inferenceParameters, pit.Node()) } getInferredTypes := func() ([]typegraph.TypeReference, bool) { // Check if the lambda expression is under a function call expression. If so, we use the types of // the parameters. parentCall, hasParentCall := node.TryGetIncomingNode(sourceshape.NodeFunctionCallExpressionChildExpr) if hasParentCall { return sb.getFunctionCallArgumentTypes(parentCall, context), true } // Check if the lambda expression is under a variable declaration. If so, we try to infer from // either its declared type or its use(s). parentVariable, hasParentVariable := node.TryGetIncomingNode(sourceshape.NodeVariableStatementExpression) if !hasParentVariable { return make([]typegraph.TypeReference, 0), false } // Check if the parent variable has a declared type of function. If so, then we simply // use the declared parameter types. declaredType, hasDeclaredType := sb.getDeclaredVariableType(parentVariable) if hasDeclaredType && declaredType.IsDirectReferenceTo(sb.sg.tdg.FunctionType()) { return declaredType.Parameters(), true } // Otherwise, we find all references of the variable under the parent scope that are, // themselves, under a function call, and intersect the types of arguments found. parentVariableName, hasParentVariableName := parentVariable.TryGet(sourceshape.NodeVariableStatementName) if !hasParentVariableName { return make([]typegraph.TypeReference, 0), false } parentBlock, hasParentBlock := parentVariable.TryGetIncomingNode(sourceshape.NodeStatementBlockStatement) if !hasParentBlock { return make([]typegraph.TypeReference, 0), false } var inferredTypes = make([]typegraph.TypeReference, 0) rit := sb.sg.srg.FindReferencesInScope(parentVariableName, parentBlock) for rit.Next() { funcCall, hasFuncCall := rit.Node().TryGetIncomingNode(sourceshape.NodeFunctionCallExpressionChildExpr) if !hasFuncCall { continue } inferredTypes = sb.sg.tdg.IntersectTypes(inferredTypes, sb.getFunctionCallArgumentTypes(funcCall, context)) } return inferredTypes, true } // Resolve the inferred types and decorate the parameters with them (if any). inferredTypes, hasInferredTypes := getInferredTypes() if hasInferredTypes { for index, inferenceParameter := range inferenceParameters { var inferredType = sb.sg.tdg.AnyTypeReference() if index < len(inferredTypes) { if !inferredTypes[index].IsVoid() { inferredType = inferredTypes[index] } } sb.inferredParameterTypes.Set(string(inferenceParameter.NodeId), inferredType) } } else { for _, inferenceParameter := range inferenceParameters { sb.inferredParameterTypes.Set(string(inferenceParameter.NodeId), sb.sg.tdg.AnyTypeReference()) } } } // getFunctionCallArgumentTypes returns the resolved types of the argument expressions to the given function // call. func (sb *scopeBuilder) getFunctionCallArgumentTypes(node compilergraph.GraphNode, context scopeContext) []typegraph.TypeReference { ait := node.StartQuery(). Out(sourceshape.NodeFunctionCallArgument). BuildNodeIterator() var types = make([]typegraph.TypeReference, 0) for ait.Next() { // Resolve the scope of the argument. argumentScope := sb.getScope(ait.Node(), context) if !argumentScope.GetIsValid() { continue } types = append(types, argumentScope.ResolvedTypeRef(sb.sg.tdg)) } return types }
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'use strict'; import { LOGIN_STATE_LOGOUT, LOGIN_STATE_REGISTER, LOGIN_STATE_LOGIN, LOGIN_STATE_FORGOT_PASSWORD, } from '../../lib/constants'; export default function formValidation (state) { switch(state.form.state) { case LOGIN_STATE_LOGOUT: return state.setIn(['form','isValid'],true); case LOGIN_STATE_REGISTER: if (state.form.fields.username != '' && state.form.fields.email !== '' && state.form.fields.password !== '' && state.form.fields.passwordAgain !== '' && !state.form.fields.usernameHasError && !state.form.fields.emailHasError && !state.form.fields.passwordHasError && !state.form.fields.passwordAgainHasError) { return state.setIn(['form','isValid'],true); } else { return state.setIn(['form','isValid'],false); } case LOGIN_STATE_LOGIN: if (state.form.fields.username !== '' && state.form.fields.password !== '' && !state.form.fields.usernameHasError && !state.form.fields.passwordHasError) { return state.setIn(['form','isValid'],true); } else { return state.setIn(['form','isValid'],false); } case LOGIN_STATE_FORGOT_PASSWORD: if (state.form.fields.email !== '' && !state.form.fields.emailHasError){ return state.setIn(['form','isValid'],true); } else { return state.setIn(['form','isValid'],false); } } return state; }
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Q: Keras custom loss: a * MAE + (1-a) * constant I am trying to implement a fairly simple custom loss function in Keras. I am trying to make the network predict a bad input case (i.e. on which it has no chance of predicting correct output), along with correct output. To try to do this, I used a loss function which allows the network to 'choose' a constant loss (8) instead of it's current loss (determined by MAE). loss = quality * output + (1-quality) * 8 Where quality is output from sigmoid, so in [0,1] How would I design such a loss function properly in Keras? Specifically, in the basic case, the network gets several predictions of the output, along with metrics known or thought to correlate with prediction quality. The role of the (small) network is to use these metrics to determine the weights to give when averaging these different prediction. This works well enough. However, in some fraction of cases (say 5-10%) the input data is so bad that all predictors will be wrong. In that case, I want to output '?' to the user instead of a wrong answer. My code complained about 1 array vs 2 arrays (presumably, identical number of y_true and y_pred are expected, but I don't have these). model = Model(inputs=[ain, in1, in2, in3, in4, in5, x], outputs=[pred,qual]) model.compile(loss=quality_loss, optimizer='adam', metrics=['mae']) model.fit([acc, hrmet0, hrmet1, hrmet2, hrmet3, hrmet4, hrs], ref, epochs=50, batch_size=5000, verbose=2, shuffle=True) It seems having two outputs is causing the loss function to be called independently for each output. ValueError: Error when checking model target: the list of Numpy arrays that you are passing to your model is not the size the model expected. Expected to see 2 array(s), but instead got the following list of 1 arrays: This was solved by passing a concatenated array instead. def quality_loss(y_true, y_pred): qual = y_pred[:,0] hr = y_pred[:,1] const = 8 return qual * mean_absolute_error(y_true,hr) + (1 - qual) * const def my_mae(y_true,y_pred): return mean_absolute_error(y_true,y_pred[:,1]) model = Model(inputs=[xin, in1, in2, in3, in4, in5, hr], outputs=concatenate([qual, pred_hr])) model.compile(loss=quality_loss, optimizer='adam', metrics=[my_mae]) Network code: xin = Input(shape=(1,)) in1 = Input(shape=(4,)) net1 = Dense(3,activation='tanh')( Dense(6,activation='tanh')(in1) ) in2 = Input(shape=(4,)) net2 = Dense(3,activation='tanh')( Dense(6,activation='tanh')(in2) ) in3 = Input(shape=(4,)) net3 = Dense(3,activation='tanh')( Dense(6,activation='tanh')(in3) ) in4 = Input(shape=(4,)) net4 = Dense(3,activation='tanh')( Dense(6,activation='tanh')(in4) ) in5 = Input(shape=(4,)) net5 = Dense(3,activation='tanh')( Dense(6,activation='tanh')(in5) ) smweights = Dense(5, activation='softmax')( concatenate([xin, net1, net2, net3, net4, net5]) ) qual = Dense(1, activation='sigmoid')( Dense(3, activation='tanh')( concatenate([xin, net1, net2, net3, net4, net5]) ) ) x = Input(shape=(5,)) pred = dot([x, smweights], axes=1) This runs, but converges to loss = const and mae > 25 (whereas a simple mae loss here achieves 3-4 quite easily). Something is still not quite right with the loss function. Since shape on y_true/y_pred in the loss function gives (?) it's hard to track what is being passed exactly. A: This issue is actually not caused by your custom loss function, but by something else: The problem arises because of how you call the fit function. When you define the model, you give it 7 inputs and 2 outputs: model = Model(inputs=[ain, in1, in2, in3, in4, in5, x], outputs=[pred,qual]) When you eventually call the fit function, you give a list 7 arrays as the input of the network but only 1 target output value called ref: model.fit([acc, hrmet0, hrmet1, hrmet2, hrmet3, hrmet4, hrs], ref, ...) This will not work. You have to supply the fit function with the same number of inputs and outputs as declared in the model's definition. Edit: I think there is some conceptual problem with your approach: how are you actually planning to define the quality of your prediction? Why are you thinking, that adding a branch of your network which is supposed to judge the quality of your network's prediction will actually help to train it? The network will converge to a local minimum of the loss function. The fancier your loss function is, the more likely it is, that it will not actually converge to the state you actually want it to be in, but to some other local and not global minimum. You could try to experiment with different optimizers and learning rates - maybe this helps your training.
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Fourou is een gemeente (commune) in de regio Sikasso in Mali. De gemeente telt 41.500 inwoners (2009). De gemeente bestaat uit de volgende plaatsen: Alhamoudoulaye Bala Baloulou Banaso Dièou Finkolo Fouguélé Fourou Galamakourou Glambéré Gouéné Kamberké Kapalaka Katiorrni Lassiribougou Lollè Louguelé N'Golpéné Naziédougou Nigolasso Noularma Ouatialy Piama Sinty Syama Taboroni Tenbleni Torokoro Zèguèrè Gemeente in Mali
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Station View is a first floor apartment situated in the centre of Pickering in North Yorkshire. It has a twin bedroom and a shower room, the property can sleep two people. Also inside there is an open plan living area with a kitchen, a dining area and a sitting area. To the outside there is off road parking for two cars to the rear of the property. Station View is a delightful property in the perfect location for a peaceful holiday. The market town of Pickering, with its range of amenities and traditional shops, cafes, pubs and restaurants, serves as the official gateway to the North York Moors National Park. The Beck Isle Museum is certainly worth a visit and walkers can make the most of the rolling hills, valleys, rivers and abundant wildlife of the North York Moors. The city of York and the Heritage Coast are all in reaching distance. Electric central heating. Electric cooker, microwave, fridge, freezer, washing machine, TV with Freeview, DVD, WIFI, selection of books and DVDs. Fuel and power inc. in rent. Bed linen and towels inc. in rent. Off road parking for 1 car. Sorry, no pets and no smoking. Shop and pub 3 mins walk. Note: Washing machine in cupboard next to shower room. Loved the place, great location close to town, and easy access to local attractions.. The flat was quiet, didn't here any noise when windows were closed. Flat was fully stocked with everything needed for a comfortable stay. Lovely flat and across the road from the heritage railway,ideal for anoraks like ourselves.. The flat was very nice, good accommodation & in a central place for everything we wanted.. The washing machine did not work, and although we reported this early in the week it was not fixed. We like to walk & it's important to me that I can wash my clothes ready for the next time! We were not informed this property was joined onto a pub that had an outside drinking area below our windows.. On most nights the noise and language from there lasted way past closing time with gangs of people shouting and laughing drunken banter until the early hours. Friday night began with extra loud youngster music and did not end until 12 - 12.30am. By the time all the hanger on people had shouted their goodbyes and cars and taxis had cleared them all away it was gone 1. am and we had had enough. Had we been informed it was next to us we would not have booked such a noisy flat. The flat itself was lovely, new and clean though. It was all very straight forward to book and the flat was lovely - great position, clean and comfortable.. We enjoyed our stay. It is a bit loud, but on the whole a very enjoyable place to stayin.. Would recommend it to our closest friends. The flat is in a great central location in Pickering, it is possible to spend time sat by the window just watching the activity in the main shopping street.. I made use of the railway to get to the starting point of a couple of walks, it is sometimes good to leave the car and get out for a day without driving. Directions to the flat were accurate, on arrival the key collection worked well and the flat was spotlessly clean. Read the visitors' book for some useful suggestions about places to visit and places to eat in town. Station view was a lovely, cosy apartment and we really enjoyed our stay.. We will return soon. Lovely apartment in a great location.. Had everything you needed for a comfortable stay. Lovely flat in a great location we have been to Pickering many times the railway and the moors it is central to them all and a good bus service on the door step for Scarborough fantastic break just to short we will be back.. Tell us about your rental experience while staying at Station View. Let us know if the listing matched your expectations. You can share your comments about the location, property owner/manager and all the unique features that made your stay a memorable one.
{'redpajama_set_name': 'RedPajamaC4'}
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An Ohio police division on Wednesday shared a video of two deer duking it out within the darkness. The conflict of antlers was recorded by the Blue Ash Police Division, which shared it on its Fb web page. The video confirmed the brawl because it moved from a grassy space to the road and again. The battle, which appeared to kick off simply earlier than 2 a.m., lasted for a number of minutes, in response to the video's timestamp. And whereas the police don't sometimes enable such conduct in the course of the road, they determined to make an exception this time, they wrote within the Fb put up. "Usually, BAPD wouldn't tolerate preventing on the street. We thought it was greatest to let nature take its course on this occasion," the police division mentioned. The video seems to complete earlier than the top of the battle.
{'redpajama_set_name': 'RedPajamaC4'}
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Welcome to SWAG 101, where the discussion is the 21st Century Hitting Model. Over the next few weeks we will be breaking down the cognitive process in hitting. In last week's issue, we took a quick look at how the eyes, brain and body work together to form a unique and complex system of recognition, timing, and decision-response. Understanding or executing this system is what separates good hitters from bad hitters. In this issue, we are looking at the idea of Immaculate Perception. Now the question is, "Is it even possible for perception to be immaculate?" Let's take a look, keeping in mind that visual acuity is both a mental and physical process. We know that everyone's reality differs slightly. For example, what you think is red, I may think is maroon or burgundy. Therefore in pitch recognition, we have the IMAGE and the OBJECT. The image is what we think we see and the object is what is really happening. We can close the gap between the two when proper visual mechanics are applied. Let's take a look at the visual setup of most hitters -just in terms of establishing balance. Believe it or not, balance is the most basic fundamental of great vision. For without balance, coordination, control, and stability are virtually impossible. Balance contributes to stabilizing the head and eyes. A hitter's imbalances contribute to the lack of visual focus and inability to track the moving ball in HD. As a matter of fact, there are so many hitters who appear to be balanced in their setup but never maintain it throughout the flight of the pitch and the swing. Think about all the hitters who wobble when the ball is in-flight, especially on the change up. Getting hitters balanced pre-pitch is easier than maintaining balance in-flight. Therefore, hitting the change up is a strength issue to be improved through balance training in your living room not necessarily the weight-room. SEPARATION: WHAT IS IT REALLY? When we separate the stride or step or load from the swing, we are separating our recognition system from our timing system. The two cannot happen simultaneously due to our human inability to multi-task those two brain functions. Hitters who put the stride (load, step or trigger) and the swing too close together are neglecting one. They are either on-time with poor recognition or recognizing it with poor timing. In order to be good consistently, we need both -and they must occur separately. We are also separating the upper body from the lower body in terms of when the rotational phase occurs. I am not going to go into rotational vs. linear here. That is an argument rooted in ignorance. They both have to happen so pick one that you believe in and go with it. But the real question is when do they happen? I believe the sequence is specific to the hitter and a good hitting coach adjusts it accordingly. However, if this separation does not happen, then body drifts forward, hips fly and pull shoulders, head and eyes out of the visual process. That is an example of poor visual mechanics. Understanding heel-plant is imperative. A lot of coaches talk about toe-touch and that is very important, but remember that heel-plant of the front foot must happen in order to maintain balance throughout the swing. Some hitters never get to heel-plant early enough to establish real balance. Then there are some that lift their front heel so high off the ground they never get it back down in time. This is how we improve stability of the head and eyes. Check out my posts over the next few weeks, as we take a look at the Kinematic Sequence. It is during this phase of the swing that anticipation, prediction, time to collision, and pitch interpretation occur. This is the fun part -well sometimes.
{'redpajama_set_name': 'RedPajamaC4'}
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BMW's largest "Sports Activity Vehicle" remains for 2006 with a number of physical modifications intended to distinguish the X5 more from its smaller stablemate, the X3. The vehicle's base 3.0i comes powered by a 3.0-liter in-line six-cylinder engine that is rated at 226 horses. Meanwhile, a 4.4-liter V-8 produces a lustier 315 horsepower, while the top 4.8is model offers an even-more pleasing 355-hp 4.8-liter V-8. A six-speed-manual gearbox is standard on the base version, with a five-speed-automatic transmission optional, while V-8 models offer only a six-speed automatic. BMW's xDrive "intelligent" all-wheel-drive system permits infinitely adjustable front-to-rear torque distribution for surefootedness on wet or snowy pavement. The X5 can tow 5000 pounds with the six and 6000 pounds with a V-8 powerplant. Among the vehicle's many upscale options is a Sport Package that adds a tauter suspension for a bit more precise handling, and an iPod Adapter is available that allows Apple's popular iPod MP3 player to interface with and be operated by the vehicle's audio system. Awesome! best car I have every driven. Great car, fun to drive and lots of cool options. Plenty of room. Best moon roof i have ever had. great sound system. Looking for a different year of the BMW X5?
{'redpajama_set_name': 'RedPajamaC4'}
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If you've recently taken a pay cut, become unemployed, or simply found your monthly bills increasing for no apparent reason, finding ways to cut back can be critical. There are several things you can to try to cut your monthly bills, and most only require a little effort on your part. Here are # ways to lower your monthly bills. Electricity is a necessity that we can't do without. But you aren't stuck paying outrageous bills. Instead, make sure that you're getting the best electricity rates possible for your home. Once you know you're getting the lowest rates, make sure you're not raising your bill with energy drains. Unplug appliances and other electricity-using devices when they're not being used, ensure that your wiring is up to date and functioning properly, and have your HVAC system checked to ensure it doesn't run more than it should. If everyone is out of the house all day, there's no reason to keep an empty house at the same temperature as a full one. A programmable thermostat allows you to set it so that the system will run and get the house to a comfortable temperature at a time you choose, typically shortly before you get home. It also allows you to change the temperature between day and night, to make for more comfortable sleep as well. If you have two vehicles, but rarely use one of them, sell it. This will save you the money for insuring it, as well as the yearly registration fees. If your first car is unavailable when you need to go somewhere, try using public transportation. With just a little extra planning, public transportation can get you to and from work, the grocery store, doctor appointments and most other things you need to get to. Groceries is another area where you have no choice but to pay for what you need. But what you need is far different than what you want. Create a weekly or monthly meal plan, and use that plan to create a shopping list that you stick to at the store. Cook cheaper meals, as well. You may love lobster and Porterhouse steaks, but if your budget only allows for hamburger and trout, that's what you need to eat. Stick to the perimeter of the store, and buy produce that is in season, even if you have a craving for something that's out of season. When it comes to coupons, there are many different types of coupons and often times you don't know about them until you get to the store. Use online resources to search coupons ahead of time which can also help you decide what meals you can make for the week. The more involved shoppers become at using coupon strategies to save money, the easier the process becomes. Many times, if you have cable, internet and phone through the same provider, you can bundle those services and save a lot of money over paying for each service individually. Take the time every few months to comparison shop and see if there are better deals available from your current provider's competitors. If there is, contact your current provider and see if you can negotiate a better deal – and if you can't, switch providers (unless you have a contract, in which case you're better off sticking with it, to avoid the early termination fees). Unlimited everything sounds great, but are you actually using it? If you're paying for services that you don't use, get rid of them. Compare the minutes you use to the various plans offered. If there's a cheaper plan that you can switch to, do so. Cancel lines that aren't being used. Contact your provider and see if you can negotiate a better deal. You can often lower your monthly mortgage payment by refinancing your mortgage. You'll have to pay closing costs to do so, but the savings in the long run might be worth it. Check with a few lending institutions and see what offers you get. If you don't get a significantly better deal, stick with what you have. Saving money on your monthly bills doesn't usually cost you anything but the time and energy it takes to do some research and talk to your various creditors to try to negotiate terms. It can be worth it for the money you'll save.
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I am so happy with this area…they seriously do treatment regarding their individuals and I'd suggest them to any one! To Get better from surgical treatment some individuals choose to hire a crutch substitute or knee caddy to assist them within their recovery from surgical procedure, then it might be returned. From Organization: Our Business brings together high-quality products, the most up-to-date know-how and wonderful customer support. And I want to include that because of the lightweightness, I had been capable of find Other people to assist finding it from my auto for use when I'd personally get there at my spot. Not remaining one to request help/generally being most unbiased, your kneewalker gave me that liberty I coveted. As you could see in my Image, I could even shoot a game of pool in the home. Crutches are becoming out of date with some people since they are certainly not hassle-free in almost any way, They're bothersome to implement and could cause even further damage. A roll about walker is often a wheeled walker product that means that you can consider weight off your reduce extremities in order to assist you in the therapeutic and/or waiting around course of action. This unit enables you to "roll about" whilst offering your injured leg or foot some assistance to stop further more harm. Knee Walker Rentals in Miami, FL are used to offer Individuals disabled and wounded the aptitude of going with regards to their normal regimen. The comfotable knee relaxation platform enables you to easily and simply have mobility. This rental item is offered from corporations servicing the Miami spot. If you're unhappy along with your knee walker, let us know inside the initially seven times you get it, and We're going to send out you a very absolutely free Trade. Employing a knee scooter following a leg accident can help you heal although nonetheless with the ability to do a number of your day by day actions. The wheeled knee walker can conveniently go ahead and take area of crutches prior to and after surgical procedure. Usually there are some people who favor not to utilize crutches completely simply because they are awkward and unreliable.
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This breast style drill's patent is not listed in the 81/34 classification but rather in class 279/64 for the chuck which uses 2 hooked jaws to grab the square edges of a tanged bit. The crank handle is also adjustable. Burkholder was listed in era city directories as "practical machinist and manufacturer of geared braces, experimental machinery, model and pattern maker". There are at least 4 examples of this drill in existence.
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A New Zealand woman panicked after swimming with a friendly dolphin who prevented her from returning to shore, illustrating the dangers of human-dolphin interaction. A woman who prefers to remain anonymous proved that swimming with dolphins is not all fun and games. After playing in the water with a dolphin locally known as Moko at Mahia Beach on the North Island of New Zealand, the woman grew tired. When she tried to return to shore, Moko kept playing, eventually stranding the exhausted woman in the cold, wintry waters. "[T]he dolphin had meant no harm," the woman told the BBC. Patrons at a nearby cafe heard her screaming for help, and set out to rescue her in a rowboat, finding her "exhausted and extremely cold, clinging to a buoy," the BBC reports. "We were playing around for a while but then when I wanted to go back in, he just wanted to keep playing," she told the BBC. "I became exhausted and started to panic." According to area residents, Moko, a friendly three-year-old bottlenose dolphin, gets "lonely and bored" in the winter when fewer tourists and swimmers play with him. As a result, he was overly eager to secure a new playmate. BBC: Inside Out: Lone dolphins - friend or foe? New Zealand scientists are worried about Moko's well-being, and the negative effects that may come from his prolonged interaction with humans, the BBC reports. Their recent studies found that "he had been scarred by boats and a fish hook." Scientists suggest that this is nothing unusual: of the 30 "lone" dolphins known around the world, "14 had already been injured or had died as a result of their interaction with humans." As the BBC explains, lone dolphins abandon their dolphin families, which can range from 2 to 25 dolphins, and actively seek the company of humans instead. In 2007, the U.S. Navy announced plans to use mammals such as dolphins and sea lions to prevent waterborne terrorist attacks, despite objections from animal rights groups who consider the practice to be dangerous and ineffective. As many as 30 sea lions and dolphins could be employed by the Navy Marine Mammal Program to detect and apprehend terrorists in the Puget Sound off the coast of Washington state. If used, the animals will be tasked with detecting underwater mines and even handcuffing suspicious divers.
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Chie Mihara Pump - No appliqués, solid color, buckle, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin, printed leather. Soft Leather. Chie Mihara Platorm Heel Pumps - Deep green leather platorm heel pumps from Chie Mihara. Material:Leather/Calf Leather/Rubber. Chie Mihara Pump - Suede effect, buckle, multicolor pattern, elasticized gores, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Ankle Boots - Suede effect, pleated detailing, basic solid color, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Morgan Pumps - Grey leather Morgan pumps from Chie Mihara featuring a closed round toe, leather branded insole and snakeskin-effect block heel. Material:Leather. Chie Mihara Fraya Pumps - Purple leather Fraya pumps from Chie Mihara. Material:Calf Leather/Rubber/Leather. Chie Mihara Flatform Sandals - Black leather sandals from Chie Mihara featuring an open toe, a slingback strap and a flatform sole. Material:Calf Leather/Rubber. Chie Mihara Mo-morgan Pumps - Teal leather Mo-Morgan pumps from Chie Mihara featuring a high heel, a round toe and a slip-on style. Material:Calf Leather/Leather/Rubber. Chie Mihara Sandals - Suede effect, no appliqués, solid color, buckling ankle strap closure, round toeline, square heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Mules - Suede effect, ruched, basic solid color, round toeline, flat, leather lining, rubber sole, contains non-textile parts of animal origin, mules. Soft Leather. Chie Mihara Elis Sandals - Black leather Elis sandals from Chie Mihara featuring an open toe, an ankle strap with a side buckle fastening, a branded insole and a chunky high heel. Material:Leather/Rubber. Chie Mihara Sandals - Laminated effect, no appliqués, basic solid color, buckle, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Saphira Sandals - Black suede Saphira sandals from Chie Mihara. Material:Leather/Suede. Chie Mihara Loafer - No appliqués. Multicolor Pattern. Round toeline. Flat. Leather lining. Leather/rubber sole. Contains non-textile parts of animal origin. Soft Leather. Chie Mihara Sandals - No appliqués, laminated effect, two-tone, buckle, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Yummy Mary Janes - Black leather Yummy Mary Janes from Chie Mihara featuring a stacked heel, a round toe and a buckle fastening. Material:Calf Leather/Rubber. Chie Mihara Blue Suede Sandals - Nuit blue suede sandals from Chie Mihara featuring an open toe, a chunky heel, an ankle strap with a side buckle fastening, a platform sole and a branded insole. Material:Leather/Suede. Chie Mihara Esther Sandals - Green leather Esther sandals from Chie Mihara featuring an open toe, an ankle strap with a side buckle fastening, a branded insole and a high block heel. Material:Leather. Chie Mihara Women's Amazon Block-heel Sandals - Chie mihara women's amazon block-heel sandals. Chie Mihara Praxa Navy Frill Heel Suede Boot - The Praxa Ante Pizarre mini boot by Chie Mihara made for Nellie & Dove in navy suede. With stylish ruffled heel and ergonomic sole. Handmade in Spain. Chie Mihara Sandals - No appliqués, basic solid color, buckle, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Quesada Sandals - Green leather and suede Quesada sandals from Chie Mihara featuring an open toe, a slingback ankle strap, a buckle fastening and a chunky mid-heel. Material:Rubber/Suede/Leather. Chie Mihara Sandals - Laminated effect, printed leather, no appliqués, two-tone, buckle, round toeline, cone heel, leather/rubber sole, leather lining, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Buckled Pumps - Ochre yellow linen buckled pumps from Chie Mihara featuring an almond toe, a brand embossed insole and a mid high block heel with a snakeskin print effect. Material:Linen/Flax/Leather/Rubber. Chie Mihara Women's Ante-eskol High-heel Sandals - Chie mihara women's ante-eskol high-heel sandals. Chie Mihara Hibo Heeled Ankle Boots - Navy blue velvet Hibo heeled ankle boots from Chie Mihara. Material:Rubber/Leather/Velvet. Chie Mihara Pump - Sueded effect, bow detailing, solid color, buckle, round toeline, leather lining, leather/rubber sole, square heel, covered heel, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Quesada Sandals - Brown leather and rubber Quesada sandals from Chie Mihara featuring an open toe, an ankle strap with a side buckle fastening, a branded insole and a low block heel. Material:Leather/Rubber. Chie Mihara Sandals - Suede effect, no appliqués, basic solid color, buckle, round toeline, square heel, covered heel, leather lining, leather/rubber sole, contains non-textile parts of animal origin. Soft Leather. Chie Mihara Ramal Loafers - Grey suede Ramal loafers from Chie Mihara. Material:Calf Leather/Rubber/Calf Suede.
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The crowd-funded wine business is predicting a stand out 2016 vintage citing "perfect" weather conditions. The company said September's record-breaking hot weather will be balanced by English vines' chalk soils, which have a two-year reserve of water to draw on - and are reporting that the grape crop will be the ripest, most concentrated and highest quality for decades. This is in contrast to France, which has had a particularly difficult 2016. A warm spring left French vine buds vulnerable to attack when hail and frost covered Northern France in early May, affecting Champagne, Chablis and Sancerre. As a result, Naked Wines are predicting 2016 could be the year that English wine edges ahead of Champagne in the quality stakes. "For the first time in English winemaking history, weather conditions have favoured English winemaking more than our French neighbours," Eamon Fitzgerald, MD of Naked Wines UK, said. "We believe the brilliant 2016 vintage and weaker sterling mean there's never been a better time than to pile in to our own produce." Winemaking is one of the UK's fastest growing industries. Over the past five years, sales of sparkling wines have risen by 80% in the UK (UHY Hacker Young). Naked Wines recently launched two new English winemakers; Charles and Ruth Simpson and ex-city banker Ian Kellett. Kellett's wines are his Old Winchester Hill Blanc de Blanc NV and Old Winchester Hill Oeil de Pedrix NV. "Should the weather keep this up it looks likely to be one of the best vintages of the last 100 years in England - this would most certainly overtake many regions of France in quality and quantity," Kellett added. "It's an exciting time to be part of English Wine and I'm looking forward to tasting the results of a brilliant British summer."
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Provide comfort for the family of Braxxtyn McMillan with a meaningful gesture of sympathy. Baby girl, Braxxtyn Kye McMillan, 16 days old, daughter of Kaitlyn Pollard and Bryan McMillan was born into this life on December 31, 2018 at Oklahoma City. She departed to her heavenly home Wednesday January 16, 2019 at Oklahoma City. Services are scheduled for 10:00 AM Saturday, January 19, 2019 at Alexander Gray Funeral Home Chapel of Wilson with Artie Farve officiating. Following services a cremation will be handled at Alexander Gray Crematory. Survivors include her Parents; Kaitlyn M. Pollard and Bryan McMillan, II; Grandparents, Michelle and Alan McGuire, Terri Huntley, Bryan and Michelle McMillan and Jason and Jennifer Pollard; Great Grandparents, Donna Arterberry, Brenda and Steve Sisney, Rubye McMillan and Mary Beth McGuire; Great Great Grandparents, Bill Harkins and Peggy Nye; numerous other family and friends. Family visitation will be held Friday from 6 to 8 PM at Alexander Gray Funeral Home of Wilson. To send flowers in memory of Braxxtyn Kye McMillan , please visit our Heartfelt Sympathies Store. We encourage you to share your most beloved memories of Braxxtyn here, so that the family and other loved ones can always see it. You can upload cherished photographs, or share your favorite stories, and can even comment on those shared by others. Love, Jennifer Martin and Rylee Barnes sent flowers to the family of Braxxtyn Kye McMillan . Michelle, I am so sorry for your loss! Will be continually praying for you, your daughter and family. Love, Jennifer Martin and Rylee Barnes purchased the Medium Dish Garden for the family of Braxxtyn McMillan . My deepest sympathies to all. I pray for peace, comfort and love.
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There are many beautiful and appropriate commemorative offerings associated with the cremation process. Whatever your vision for an end-of-life ceremony, we are dedicated to assisting you in creating the cremation service you desire. An Lac Cremation and Funeral Services understand what service really means. Boutique-style service offers the luxury of attention to detail and personalization in every aspect of your arrangements, with reasonable options that make a funeral affordable to every family. Our experienced, licensed funeral directors specialize in helping families arrange a cremation service that is both comforting and appropriate. We offer complete funeral, cremation, and memorial services for families of every faith, culture, and lifestyle. Our professional team stands ready to serve you at any hour of the day or night, every day of the year.
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This illustration made available by NASA shows the rover Opportunity on the surface of Mars. The exploratory vehicle landed on Jan. 24, 2004, and logged more than 28 miles (45 kilometers) before falling silent during a global dust storm June 2018. There was so much dust in the Martian atmosphere that sunlight could not reach Opportunity's solar panels for power generation.
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Mixed media: film reviews A Quiet Passion; The Salesman: have a look at the film reviews of the month. Brilliantly acted, A Quiet Passion is a hymn of praise and sorrow for the socially excluded. A Quiet Passion written and directed by Terence Davies. 125 minutes The great Emily Dickinson published in her lifetime fewer than a dozen poems. She died unknown, unmarried, unfulfilled. Terence Davies is celebrated for his early autobiographical films, growing up gay and celibate in mid-20th century working-class Merseyside. This may seem a long way from respectable, prosperous, mid-19th century Massachusetts, but Davies's theme – life denied and unlived – would be familiar to many. A Quiet Passion makes of the life of a recluse, a hymn of praise and sorrow for the socially excluded. It's deeply moving to see smart, funny, caring, young Emily, so full of life, buried by loneliness and the expectations of her time and place. Apart from the opening scene, we never see her travel further than the picket fence of her family home. But it's not grim, or a slog. The scenes where she, her sister and close friend Buff genteelly mock the pomposities and pieties of visiting relatives, neighbours and clergymen, are very funny. The younger Emily is principled, happy, close to her siblings, even scandalously rebellious – all within limits, though. Time passes, nicely captured in family studio portraits as faces become heavier, sterner, more anxious. Her parents die; people move away. She gradually withdraws. To her room, to her cryptic poetry. A Quiet Passion is not perfect – male roles are underwritten. And it's difficult, at first viewing, to take in the short readings from her poetry. But it's focused, brilliantly acted – and it cuts you up. ★★★★ ML The Salesman The Salesman – a subsiding Tehran flat is just the start of their problems… written and directed by Asghar Farhadi. 125 minutes. A married couple have to leave their Tehran flat because of subsidence caused by construction work. An actor colleague – they are appearing in an amateur production of Death of a Salesman as Willy and Linda Loman – offers them a flat until they are sorted. He doesn't say that the previous tenant was a sex worker, receiving clients there. When the wife lets a man into the flat, thinking it's her husband, she is attacked and injured. The husband, against his wife's wishes, decides to trace the attacker who has left his phone, and, nearby, we find out, a van. More arty and elusive than Farhadi's Iran-set A Separation and About Elly, it's again an absorbing, unhappy study in social roles and behaviour. The wife, with compassion and perception, comes out of it all better than the husband, encumbered as he is by pride and ego. ★★★ ML This article is from the April 2017 issue of New Internationalist. New Internationalist Editorial New Internationalist is a leading independent media organization dedicated to socially conscious journalism and publishing. We are proud to be a multi-stakeholder co-operative co-owned by our workers and over 3,600 investors. More about New Internationalist Editorial Commemorating Hong Kong's lost youth Husna Ara finds Blue Island a confused documentary, bogged down by form and lacking in political nuance. The alternative film review Malcolm Lewis on two standout releases in world cinema. Malcolm Lewis weighs up a selection of independent and studio-produced films from the global zeitgeist. Malcolm Lewis on Karim Aïnouz and Céline Sciamma's most recent contributions to parallel cinema. Malcolm Lewis on the latest releases in parallel cinema: The Mole Agent (El agente topo), directed and written by Maite Alberdi... Malcolm Lewis reviews Luxor directed and written by Zeina Durra; Shirley directed by Josephine Decker. The radical film review The Uncertain Kingdom by Various; The Australian Dream directed by Daniel Gordon; Classics: The Happy Family co-written and... Malcolm Lewis on the latest arthouse releases. Mixed media: film Malcolm Lewis on the latest in alternative cinema. Spotlight: Kyla Simone Bruce Migration, identity, gender – Subi Shah tackles the big issues with filmmaker Kyla Simone Bruce. Malcolm Lewis reviews the latest releases in radical cinema. Malcolm Lewis reviews Woman at War, directed and co-written by Benedikt Erlingsson; The Third Wife, directed and written by Ash... Malcolm Lewis reviews Disobedience directed by Sebastián Lelio and The Workshop directed by Laurent Cantet. Tehran Taboo written and directed by Ali Soozandeh;The Heiresses (Las Herederas) written and directed by Marcello Martinessi. Film picks of the month Mountains May Depart, by Jia Zhangke, and Makala, by Emmanuel Gras are reviewed this month. Our favourite films from the world in December Dolores directed by Peter Bratt; Félicité directed and co-written by Alain Gomis. Our November film picks from around the world I Am Not a Witch, by Rungano Nyoni; Menashe, by Joshua Z Weinstein. Reviewing our favourite films of the month Films from the world that should be on your watchlist. Quest, and In between (Bar Bahar): our monthly review of our favourite films of the month. Our picks from the Toronto Hot Docs Highlights from the largest documentary film festival in the world. New Internationalist's picks for films of the month Machines; The Other Side of Hope: what should be on your watchlist this month. The Handmaiden; Frantz: have a look at the film reviews of the month. Our pick of recent and new releases. FiSahara: the world's most remote film festival The festival offers refugees and international guests excitement and windows into forgotten worlds, writes Stefan Simanowitz. Mixed Media: Films I, Daniel Blake, directed by Ken Loach; The Innocents, directed and co-written by Anne Fontaine. The Clan, directed and co-written by Pablo Trapero; Urban Hymn, directed by Michael Caton-Jones. And finally... Toni Myers Training astronauts to shoot film? All in a day's work for the Canadian documentary filmmaker, writes Cristiana Moisescu. Mixed Media: Best of 2015 The films, music and books that made the grade this year. Patricio Guzmán's search for the truth Roxana Olivera meets the documentary filmmaker renowned for delving into Chile's dark past. Xiaolu: 'If you can't sell in China you are nothing' The award-winning novelist and film director tells Graeme Green about growing up in rural China, freedom, censorship and... Confronting the seven myths of Israel's history Israeli filmmaker Lia Tarachansky tells Frank Barat about the challenges and rewards of making On The Side of the Road. Ken Loach: why I support a cultural boycott of Israel The acclaimed film director talks to Frank Barat about Palestine, politics, and why he wants to keep causing trouble. John Pilger: Australia's silent apartheid The investigative journalist and filmmaker tells Hazel Healy about his new film, and explains why Australia is still on an... Support The Spirit Level Film! Producer/Director Katharine Round explains how you can help bring the message about equality to the screen. How to nail a dictator A new film is testament to 'never giving up', as Anna Bevan reports from Guatemala. Best of the Arts 2011 We watched, we read, we listened: New Internationalist's favourite films, books and music from last year. Horror flick: Mrs T at the multiplex Forget Scream, The Exorcist and Jaws: The nightmare on Downing Street is coming to a cinema near you. Film review: We Were Here A compassionate and inspiring film about the AIDS epidemic in 1980s San Francisco. Film review: Resistance What if the Germans had invaded the Welsh valleys during the Second World War?
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Atherigona kivuensis är en tvåvingeart som beskrevs av Deeming 1981. Atherigona kivuensis ingår i släktet Atherigona och familjen husflugor. Artens utbredningsområde är Kongo. Inga underarter finns listade i Catalogue of Life. Källor Husflugor kivuensis
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25 items found that match your criteria. The ProClip is a mounting bracket for the Mazda 2's dashboard. Onto the ProClip you can install e.g. a holder for your mobile phone or PDA or a handsfree set etc. Safe and convenient -always within easy reach. The ProClip is car specific and easy to install. The installation is quick, no special tools or dismantle of the dashboard is required and it will not damage the interior of the Mazda 2. Made in black ABS plastic. Comes with detailed instructions. Charging cable with cig-plug. With USB Type-C connector, 2A charging. 12/24V. Angled connector. Charging cable with cig-plug. With USB Type-C connector, 2A charging. Can be used with Brodit passive holders. 12/24V. The USB Type-C connector house is angled. This means that the cable goes either on the back or on the front side, depending on which way you connect the cable to the device. The active holder charges your OnePlus 2 when it is in the holder. You can choose to connect the cig-plug to the car's 12 Volt socket, or to remove the cig-plug adapter and connect the USB cable to the car's (or stereo's) USB connector. The active holder charges your OnePlus 2 when it is in the holder. The holder is attached onto a tilt swivel and can be adjusted in order to avoid light reflection. Connects to the vehicle's cigarette lighter socket, 12/24 Volt. Attach onto a ProClip Mounting Platform in your car. The ProClip is a mounting bracket that you attach onto the Mazda 2's dashboard. It provides a mounting platform for mobile phones and other devices that you want to have within easy sight and reach in the car. Safe, neat and convenient! The ProClip has a perfect fit, it is custom made for each Mazda 2 to ensure a secure base for installations.
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Serie A Shirt Sponsor Revenues - Ranked By Adam Aladay Nov 24, 2020, 7:30 PM GMT Juventus have a major deal with Jeep | Jonathan Moscrop/Getty Images The benefits of a lucrative shirt sponsorship deal are now more important than ever, especially considering the financial impact of the coronavirus pandemic. But it isn't all about money when it comes to shirt sponsors (although a very, very large part of it is), as it's also about how this logo compliments the jersey. Indeed, some of the finest shirts down the years have become synonymous with a certain logo, helping create an aesthetic. La Gazzetta dello Sport (via Sempre Milan) have now released the revenues each team in Serie A are receiving from their current shirt sponsorship deals. And while the total revenue for the league is up €5m from the year before to €169m, it's still considerably behind the likes of the Premier League in this department. Juventus 3-1 Sassuolo: Player ratings as Old Lady go fourth in Serie A 90min's player ratings as goals from Aaron Ramsey and Cristiano Ronaldo helped Juventus seal a 3-1 win over Sassuolo. Mitch Wilks Napoli to reignite Kieran Tierney pursuit in summer Napoli plan to reignite their pursuit of Arsenal left-back Kieran Tierney next summer but want someone like Chelsea's Emerson Palmieri on loan first. Tom Gott Andrea Pirlo must summon Juventus DNA to keep pace in Serie A title race Andrea Pirlo proved he still has that winning DNA after Juventus defeated Milan at San Siro, and they must continue in the same vein to reach the Serie A summit Max Cooper Remembering AC Milan and Inter's last Serie A titles Milan and Inter are tangled in a two-horse race for the Serie A title. 90min looks back on when the pair each won the Scudetto last. But who is dominating when it comes to sponsorship deals and who is lagging behind? 20. Lazio Lazio don't have a main sponsor | DeFodi Images/Getty Images Amount: €0.5m Sponsors: Frecciarossa Well, that's not great, is it? Lazio were made to end their partnership with MarathonBet in 2019 and have struggled to find a new partner since. However, this little sum of cash (y'know, relatively speaking) comes from a recent partnership agreement struck with Frecciarossa - a high speed train. 19. Spezia The Ten logo features in the centre but isn't actually all that prominent....somehow | Alessandro Sabattini/Getty Images Sponsors: Ten, Iozzelli Piscine, Pediatrica It's not good if even Spezia are earning more with their shirt sponsorship deals. They partnered with food and beverage company Ten in 2019 and we're still not sure exactly how, but it works. Iozzelli Piscine - a swimming pool customisation and installation company - also feature on the sleeve and Pediatrica are advertised on the back, just to add to the organised chaos on the shirt. 18. Sampdoria The Very Mobile logo is very loud | Paolo Rattini/Getty Images Amount: €1m Sponsors: Very Mobile, Ibsa Sampdoria actually agreed a deal with Very Mobile in November for the 2020/21 campaign. After it was confirmed, it was said this was a particularly important collaboration at a time when football needed to be better connected with its fans. IBSA also extended their back of shirt sponsor with the club in September. 17. Crotone Crotone's away shirt doesn't leave much to the imagination | Stefano Guidi/Getty Images Sponsors: San Vincenzo, Envi, Vumbaca, Biemme Perhaps the main problem sponsors may have with Crotone is that kits such as the one above will almost certainly distract from the actual logos on the shirt....which is pretty tough to do. 16. Genoa Genoa recently teamed up with Banca Sistema | Alessandro Sabattini/Getty Images Sponsors: Banca Sistema, Synlab, LeasePlan Banca Sistema took over as Genoa's main sponsorship partner for the 2020/21 campaign after their deal with Zentiva had ended. Genoa's sleeve sponsorship agreement with Synlab has also helped the club reach new heights with regards to their revenue. 15. Benevento Benevento's sponsors dominate the shirt | DeFodi Images/Getty Images Sponsors: IVPC, Rillo Construction, Pastificio Rummo, Don Peppe Benevento didn't hold back when they were promoted to Serie A, did they? The partnerships with Rillo Construction, Pastificio Rummo and Don Peppe all accompany the club's main sponsor IVPC. Well, it doesn't exactly accompany it, but rather just clashes with....well, everything. 14. Verona Verona have a number of sponsors | Chris Ricco/Getty Images Sponsors: Sinergy, Winelivery, Trivellato, VertroCar A partnership that is built on being 'full of energy', Sinergy have been associated with Verona since 2018/19 and they are now into their third successful season with the club. Verona are also partnered with Winelivery as a co-sponsor, while Trivellato feature on the sleeve. 13. Parma Parma have made a slow start to the season | Giuseppe Bellini/Getty Images Sponsors: Cetilar, Old Wild West, Canovi, Viva la Mamma PharmaNutra SPA Group initially started out as the medical partner to Parma before the Cetilar brand became the main sponsor of the shirt and was part of the club's famous promotion to Italy's top flight. A partnership that has come a long way in a short space of time, with the brand and the club both benefiting from the deal. Old Wild West - a burger and steak house franchise - became the second sponsor for the start of 2020/21, having previously been the back-of-shirt advertisement. 12. Udinese Dacia features prominently in the centre | Alessandro Sabattini/Getty Images Sponsors: Dacia, Vortice, Prosciutto San Daniele, Bluenergy With Udinese reaping the benefits of their partnership with Dacia, they agreed to a new three-year deal with the car manufacturer in September. Dacia, along with Vortice, have helped provide a steady amount of revenue to support Udinese's outlay in recent years. Bologna are receiving a healthy revenue from their sponsorship deals | Paolo Rattini/Getty Images Sponsors: Facile Ristrutturare, Selenella, Scala, Illumia Bologna expanded their social and economic outreach as they took on four sponsors for the 2020/21 season, with Facile Ristrutturare (Easy Restructuring) the main partner. The investments from these companies despite the impact of the COVID-19 pandemic were major strides forward for the club. 10. Cagliari Cagliari have two sponsors on the front of their jersey | DeFodi Images/Getty Images Sponsors: Regione Sardegna, Ichnusa, Arborea, Tiscoli Sure, there are two large sponsors on the front of Cagliari's shirt, but adidas produced three fairly stunning kits for the 2020/21 season...which just about cover up the logos. 9. Torino Torino's shirt is packed with sponsors | DeFodi Images/Getty Images Sponsors: Suziki, Beretta, N.38 Wuber, Edilizia Acrobatica Well, Torino really haven't held back with their shirt sponsors, have they? Suzuki initially teamed up with Torino in 2013/14, joining as a commercial partner. But they became the club's main sponsor for the start of the 2015/16 campaign. Additionally, Torino consolidated their relationship with F.lli Beretta Group by adding 38 Wuber to the sleeves to accompany the Fratelli Beretta 1812 logo on the front. 8. Atalanta Plus500 became the main sponsor in August | Alessandro Sabattini/Getty Images Sponsor: Plus500, Radici, Automha, Gewiss Plus500 teamed up with Atalanta in August, replacing RadiciGroup as the club's main sponsor from the start of the 2020/21 season. Plus500 had already partnered with BSC Young Boys and Legia Warsaw in 2020 prior to striking an agreement with Atalanta, while they are also the leading sponsor for Atletico Madrid. It's quite the lucrative deal for Atalanta, who also advertise Automha on the sleeves of their shirts and Gewiss on the back. 7. Napoli Napoli's kits are unusually tight | DeFodi Images/Getty Images Sponsors: Lete, MSC Crociere, Kimbo For many Napoli fans, €9m is nowhere near enough for the Lete and MSC Crociere logos to be dominating the front of the jersey. The logos draw attention away from the actual beauty of the shirt, and instead we are often sucked into staring at the prominent writing in the centre. Lete and Napoli have been partners since 2005, but gaining just €9m from three different sponsors is hardly spectacular, is it? 6. Milan Milan's kits are a classic | DeFodi Images/Getty Images Amount: €10m Sponsors: Fly Emirates Milan extended their longstanding partnership with Fly Emirates in the summer by signing a new three-year deal with them to keep the airline on the front of their shirts. A partnership that was initially brought about to help promote excellence, innovation, elegance and style, Milan will be staying with Fly Emirates until at least the end of the 2022/23 season. Perhaps what is most exciting for Rossoneri fans, however, is that this new deal actually saw the club agree to take on other principal partners as well, meaning greater revenue down the line. 5. Inter Pirelli has become synonymous with Inter | Jonathan Moscrop/Getty Images Sponsors: Pirelli Inter and Pirelli - it just works, doesn't it? Whether it be with the black and blue strips, or the white changed kits, the Pirelli logo just doesn't ever really seem to be out of place on the Inter shirt. But with just €11m coming in from this iconic partnership, Inter are said to be keen to not renew their deal with Pirelli, which expires in the summer of 2021. Let's just enjoy it while we can, eh? 4. Roma The Qatar Airways logo compliments Roma's kits | Giuseppe Bellini/Getty Images Sponsors: Qatar Airways, Iqoniq, Hyundai After reaching the semi-finals of the Champions League back in 2018, Qatar Airways became Roma's seventh shirt sponsor in their history, initially becoming the main sponsor of the men's team. They also agreed to become the main global partner of the Roma women's team for the start of the 2020/21 campaign. The colours of the logo have often complimented the jersey, making it one of the most appealing tops to purchase in European football. 3. Sassuolo Sassuolo's owners are also the club's main sponsor | Chris Ricco/Getty Images Sponsors: Mapei Sassuolo? Third? Wait, what? Well, it may come as a shock to see them so high up this list, but their sponsor just so happens to be the owner of the club - Mapei. The stadium was also controversially renamed the Mapei Stadium back in 2013, but their budget has been steadily increasing in more recent times, resulting in better investments and a better chance of holding onto their star players. 2. Fiorentina Fiorentina are in a similar position to Sassuolo | DeFodi Images/Getty Images Amount: €26.2m Sponsors: Mediacom, Estra, Prima.it Wait? Fiorentina now? Yep, and you may be able to guess why this is the case. Mediacom founder Rocco Commisso bought Fiorentina in 2019, with the deal being valued at around €160m. Commisso actually tried to buy Milan the year prior, with negotiations reaching the final stages before it ultimately fell through. The simple yet stylish Mediacom logo features prominently on the front, while Estra is advertised on the sleeve and Prima.it is also on the back. It's not that much of a surprise to see Fiorentina this high anymore, is it? Ronaldo has been key to helping Juventus secure sponsorship deals | DeFodi Images/Getty Images Sponsors: Jeep, Cygames Juventus top this list, and it's not even close. The Italian giants and Jeep are united not only by their style and design, but also by their desire to be the best as well as by their histories. There has already been a reworking of the agreement between the pair to hand Juve more money, and there are suggestions that talks over a new deal began immediately after this to extend their partnership further. For more from Adam Aladay, follow him on Twitter!
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package org.createnet.raptor.common.dispatcher.events.listener; import org.createnet.raptor.common.dispatcher.DispatcherService; import org.createnet.raptor.common.dispatcher.events.StreamApplicationEvent; import org.createnet.raptor.events.type.DataEvent; import org.springframework.beans.factory.annotation.Autowired; import org.springframework.context.ApplicationListener; import org.springframework.stereotype.Component; /** * * @author Luca Capra <[email protected]> */ @Component public class StreamApplicationEventListener implements ApplicationListener<StreamApplicationEvent> { @Autowired DispatcherService dispatcher; @Override public void onApplicationEvent(StreamApplicationEvent event) { DataEvent streamEvent = event.getDataEvent(); if (!streamEvent.getDevice().settings().eventsEnabled()) { return; } dispatcher.notifyDataEvent(streamEvent.getStream(), streamEvent.getRecord()); } }
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OCT 10, 2018 | BELGIUM Software: Strengthening the EU Economy 11th of October 2018 at 17:30 BMW Brand Store On October 11 in Brussels, BSA hosted an event to explore how the software industry contributes to economic growth, creates jobs, and drives innovation across the Europe. In a keynote address, Eric Peters, a Senior Adviser to Mariya Gabriel, European Commissioner for Digital Economy and Society, explained that is clear for the European Union, software is an essential sector. Mr. Peters stressed that today software is everywhere and to continue the sector's growth and further its impact, the EU is investing heavily in AI, digital skills, and cybersecurity. Chris Hopfensperger, Executive Director of Software.org, presented the foundation's latest study, "The Growing €1 Trillion Economic Impact of Software," with data and analysis from The Economist Intelligence Unit. He then joined a panel to dive into the results and discuss the future impact of software in Europe with Carmina Coenen, Director of Solution Engineering at Salesforce, Samantha Grenville, Global Head of Corporate Public Policy Practice & Consulting Director, North America at the The Economist Intelligence Unit, and Georgios Petropoulos, Research Fellow at Bruegel. The panel discussed a range of issues impacting the software industry from the future of work and digital skills to AI and cybersecurity. Keynote Speaker: Eric Peters, Senior Adviser to Mariya Gabriel, European Commissioner for Digital Economy and Society Presentation of "The Growing €1 Trillion Economic Impact of Software": Chris Hopfensperger, Executive Director, Software.org: The BSA Foundation Panel on "Software across sectors: The future impact of software in Europe" Carmina Coenen, Director Solution Engineering, Salesforce Samantha Grenville, Global Head, Corporate Public Policy Practice & Consulting Director, North America, The Economist Intelligence Unit Chris Hopfensperger, Executive Director, Software.org: The BSA Foundation Georgios Petropoulos, Research Fellow, Bruegel More information: The Growing €1 Trillion Economic Impact of Software Virtual Event: BSA IT Roundtable BSA's Thomas Boué hosts a virtual roundtable with Ammar Alkassar, State Commissioner for Strategy and Chief Information Officer of the Saarland Government in Germany. Tech Legislation To Watch in 2021 Protocol, January 2, 2021. "One of the focuses of an economic package at the beginning of next Congress will be finding a deal on how to increase the availability and affordability of high-speed internet access," said Aaron Cooper, vice president of global policy at BSA. BSA in the News | Jan 02, 2021
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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Muse is the beautiful blonde who spin heads of men.She is a fashion lover who always comes with beautiful clothes and as she walks in the door she begins to smile and her smile would not leave you calm. This girl in general can not leave any man calm . She is full of desire and conveys it around with the most accusing force.
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MEGATRON'S CONCERNS GO past destroying Optimus Prime and the Autobots, y'know. A Megatron performer at Universal Studios Hollywood took a visitor asking for a selfie as an opportunity to berate her on selfie culture and the millennial generation. He has a lot of opinions on it, for a villainous fictional robot. When will you learn that your status updates mean zero to nothing to ANYONE, EVER. It doesn't matter what social network you post it on – worthless! Use your mind, create new memories, interact, don't just add it to a library of forgotten photographs. Ugh, how disappointing your generation is. Well. That's us told. Cheers, Megatron. Email "Megatron drops some serious truth bombs about selfie culture". Feedback on "Megatron drops some serious truth bombs about selfie culture".
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The album 'Graffiti on the Train' was well received by its critics and commercially successful. Which band from Wales was behind this release in 2013? Which of the following children's diseases can be dangerous if you are pregnant? On the 25th of March 2013 the fifth studio album by the American indie rock band The Strokes was released. The album includes the single "All the Time". What is the albums title? In 2001 Eminem made the singer behind the 2013 album 'Girl Who Got Away' world-renowned. This time the album features the rapper Kendrick Lamar. Who is the singer?
{'redpajama_set_name': 'RedPajamaCommonCrawl'}
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New California law bans State Bar's pursuit of corporately owned law firms The State Bar's attempt to change the practice of law in California meets an abrupt end – for now Nancy Drabble Saveena K. Takhar The State Bar of California's main mission is to license and discipline attorneys, so you may have been surprised to hear of their escalating efforts to open the door for corporations and paraprofessionals to practice law. For the last four years, the State Bar has been taking increasingly aggressive steps to deregulate the practice of law under the guise of "closing the justice gap." Specifically, their proposals would authorize unsupervised non-lawyer paraprofessionals to offer certain legal services and allow corporations to own law firms, share legal fees, and even directly practice law under some circumstances. In 2018, the State Bar formed a task force to study regulatory changes, then commissioned a misleading study that was released in 2019. That led to recommendations in 2020 to create two working groups: one to recommend parameters for a "regulatory sandbox" to permit the corporate practice of law, and the second to license unsupervised paraprofessionals. Unfortunately, both working groups were severely biased in their membership. The State Bar appointed people to these groups, including several academics from out of state and even out of the country, who were already unbending advocates for their point of view. This approach reflected a coordinated nationwide effort by a coterie of advocates, including in states such as Arizona which removed its rule barring fee-sharing between lawyers, and Utah, which also initiated a "sandbox" program regarding new legal ownership models. While a few bar organizations, including CAOC, were permitted to designate members of the working groups, those members were routinely outvoted in the stacked committees. In September 2021, the paraprofessional working group released its report, recommending allowing non-lawyer paraprofessionals to practice law and split fees with attorneys. Despite receiving hundreds of letters in opposition from legal aid groups, bar associations, and individual attorneys, the State Bar continued to march forward with its recommendations and largely dismissed serious substantive concerns as protectionist. Corporate ownership of law firms and splitting legal fees with non-lawyers has been banned by common law and statute, due to grave concerns that it could undermine consumer protection by creating inherent conflicts of interests that fundamentally infringe on the duties attorneys owe to their clients. Corporations are driven by profits and demands for returns to shareholders, and do not have the same ethical duties and are not subject to the same regulatory oversight as attorneys. The Bar marched forward The State Bar used questionable methods for the Closing the Justice Gap Working Group as well as the Paraprofessional Program Working Group. The Bar utilized hundreds of hours of staff time and a substantial amount of State Bar resources. Records obtained through the Public Records Act revealed that the Bar also signed contracts with outside consultants for over $200,000, paid for lobbyists to advance its agenda, and even paid for online ads to try to attract more favorable public comment. As it became clear that the State Bar could not be deterred from its push to authorize non-lawyers to practice law and allow corporations to own law firms, the Legislature sought to stand up for consumer protection. First, Assembly Judiciary Chair Mark Stone and Senate Judiciary Chair Tom Umberg submitted an unprecedented joint letter in December 2021 urging the Bar to reconsider its efforts, particularly in light of the inherent conflicts of interest any corporation would have in serving shareholders rather than legal clients. The Chairs admonished the Bar to focus on their core mission of protecting the public and addressing critical issues in the discipline system. The legislature acts, the governor agrees When it became clear, yet again, that this warning would not deter the State Bar, Assemblymember Stone and Senator Umberg amended Assembly Bill 2958, the annual State Bar dues bill, to enact statutory limitations to ensure that the Bar correct its course. The amendments to AB 2958 require the State Bar to: (1) provide very specific information regarding the funding spent on these efforts since 2018; (2) prohibit efforts to pursue corporate ownership of law firms and splitting legal fees with non-lawyers; (3) require future activities prioritize increased access for low-income individuals, small businesses, and people eligible for representation from legal services organizations; and (4) explicitly prohibit any proposed changes to the restrictions on the unauthorized practice of law. This statutory language would permanently block the "sandbox" activities and would freeze any paraprofessional proposal until January 2025. In the intervening two years, the State Bar can discuss its paraprofessional ideas with legal services organizations that it has previously ignored or diminished. The State Bar opposed these amendments, arguing that discipline is not its sole mission and that it is also charged with increasing access to the legal system. It advocated for a counter set of amendments, which were rejected by Chairs Stone and Umberg. Numerous legal services organizations, CAOC, California Employment Lawyers Association, California Defense Counsel, and others supported the passage of AB 2958 with these important protections. We conveyed to legislators that there are approaches to increasing access to justice through better funding for legal services, better staffing for self-help centers and more utilization of pro-bono services that do not carry the risks inherent in allowing non-lawyers to represent clients in sensitive legal proceedings and allowing for corporate ownership of law firms. AB 2958 as amended was approved overwhelmingly by both houses and was signed by Governor Newsom. The bill was passed as an urgency measure, so it went into effect immediately. This guarantees that the bar cannot precipitously submit its paraprofessional proposal to the California Supreme Court or the Legislature before the restrictions go into effect. While this is a great victory in the fight for consumer protection for vulnerable legal clients, the battle will continue. Nancy Drabble came to CAOC in 1986 after a stint with Ralph Nader's consumer rights organization, "Nader's Raiders." At CAOC, she was a behind-the-scenes player in the "napkin deal" crafted at Frank Fat's restaurant in 1988, helped defeat the "Terrible 200s" initiatives in 1996 and has played an instrumental role in budget negotiations to protect the courts. A native of Los Angeles, Drabble received her law degree from UC Berkeley. Saveena K. Takhar is the legislative counsel at Consumer Attorneys Association of California. She holds an M.B.A. from Cal State Sacramento and is a 2014 graduate of University of the Pacific – McGeorge School of Law. Columns - Consumer Attorneys of California
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Q: Resize of the front when using SideNav - Materialize I'm making a website with Symfony and Materialize, and my client wants to have the menu on the side. I used the documentation http://materializecss.com/side-nav.html to make it, and managed to make the side menu on the left. But I have now two problems: * *first, not important, when I press alt on Firefox, it makes the windows resize a little by making the top menu appears, and the side menu goes from left to right. It's kinda annoying, but not that important. *second, the content under the side menu is hidden, and doesn't resize to make everything appears. I tried to make a div and put in the css a margin-left, but it didn't work. Here is my code html: <nav> <ul id="slide-out" class="side-nav fixed"> <li><a href="#!">First Sidebar Link</a></li> <li><a href="#!">Second Sidebar Link</a></li> </ul> <a href="#" data-activates="slide-out" class="button-collapse"><i class="mdi-navigation-menu"></i></a></nav> And here is the js: $('.button-collapse').sideNav({ menuWidth: 300, // Default is 240 edge: 'right', // Choose the horizontal origin closeOnClick: true // Closes side-nav on <a> clicks, useful for Angular/Meteor }); $('.collapsible').collapsible(); It's only the code in the documentation, and I just have these problems. If anyone has a solution, Thanks a lot ! A: Regarding your second question: did you offset the non-side-nav content when the side-nav is open? Something like this: #app-body{ padding-left: 320px; @media only screen and (max-width : 992px) { padding-left: 10px; } } This ensures that on large screens, my content is offset by 320px (which is the width of my sideNav, but the when sideNav is closed (when the screen is under 992px wide), the padding is removed.
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CORPORATE EXCELLENCE FULIFE Group Holdings Pte Ltd www.fulife.sg FULIFE Group is a health, wellness and lifestyle company that invests and collaborates heavily in the research and supply of premium quality products, services and technology that will bring about improved and enhanced health and well-being, as well as, a richer and more fulfilling lifestyle and experiences for its customers. Founded in Singapore on March 2017 with a team of high-calibre Singaporeans who aim to provide a good ecosystem and opportunities for all to be part of their extraordinary journey in providing good health and wellness and establish new entrepreneurs in a holistic environment. FULIFE Group envisions to be an international platform that embraces good health and establish entrepreneurs in a holistic environment. The global headquarter is in Singapore with regional presence in Malaysia, Indonesia, Philippines, Vietnam, Cambodia, Myanmar, India, China and Chinese Taipei. Corporate Culture and Company Activities As a young company that is growing and expanding rapidly, operations and corporate goals are subjected to constant changes, for good reasons of course, to seize the market opportunities and ensure the bottom line. As such, decisive actions and change management is key to enable the company to be able to operate in what some might feel in a such a frenzy manner. Initiatives and new implementations are thrown on the table and agreed upon quickly at the management level. The information is disseminated to the corporate staff via circulars and then followed by training where needed. The next group of people to be informed and to be trained are leaders of direct selling sales force. Following that, information dissemination is carried out through mobile chat groups and email. As a closely knitted family, FULIFE has an open-door policy, that encourage each and every staff to openly share their ideas, views and provide feedback through direct channels ie. in person, through working chat groups, emails as well as during official meetings. FULIFE is actively involved in community activities, including organising of events and sponsorship. These include bonding events with the beneficiaries of APSN through activities like cooking, baking and handicrafts activities. In May 2019, the Group supported the Pasir Ris East Mothers' Day Celebration, sponsoring red roses to all the mothers as well as the Top 2 Lucky Draw Prizes. In June 2019, it was also privileged to have the opportunity to support the Yew Tee Grassroots Organisation at their Merdeka Generation Appreciation event, held to honour some 300 Merdeka Generation residents for their contributions to Singapore's nation-building. Achievements and Impact Through innovation and technology, FULIFE has been able to grow quickly and respond effectively to market movement and trends to enable its business to compete with other established peers and the bigger boys in the market. Within the first year of operations in 2017, the Group achieved over SGD$3M in revenue with about 2,000 customers. In the second year of operations, through an equipped direct sales force, FULIFE was able to reach markets in regional cities and tripled its sales revenue to over SGD$10m and a customer base of about 6,000. Today, the Group extended its market reach to regional cities including, Johor, Kuala Lumpur (Malaysia), Jakarta, Medan, Batam (Indonesia), Manila, Ilo Ilo (Philippines), Phnom Peng (Cambodia), Taipei and various parts of China, including Shenzhen and Guangxi. In Singapore, as the founding city and headquarter, FULIFE has a total of 8 offices, catering to corporate operations, sales and marketing showrooms including three within or just outside the Central Business District, as well as a design, development and entrepreneur space co-located within Temasek Polytechnic. "Through innovation and technology, FULIFE has been able to grow quickly and respond effectively to market movement and trends to enable its business to compete with other established peers and the bigger boys in the market." FULIFE has also established overseas offices in Kuala Lumpur, Jarkarta, Batam, Guangxi and upcoming offices in Taipei, Shenzhen and Manila. To support such rapid growth and expansion, the Group needed a strong human capital to run with them. The staff at FULIFE are encouraged to look at their daily tasks innovatively and seek to improve business processes. The management at FULIFE have installed a staff recognition system to reward staff who have shown initiative in improving business operations. The management team also conduct informal discussions with all their staff to hear them out and exchange ideas on how to improve FULIFE's business operations as well as sales and marketing. The Group values the opinions and contributions of everyone in the company. Future Direction FULIFE will continue its rapid growth both locally and overseas. The Group will continue to expand its range of products and services to capture new market segments. It will also be looking at untapped markets including India, Europe, Australia and America.
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HomeThe research journalNewsDiphtheria: identification of a penicillin resistance gene Before the vaccine era, diphtheria was the most deadly respiratory infection in young children. There are still outbreaks of diphtheria in some world regions and cases can occur among unvaccinated individuals, with severe consequences. Antibiotics are vital in treating diphtheria, and the emergence of antibiotic resistance is a major public health concern. A team of Institut Pasteur scientists has identified the origins of penicillin resistance in the bacterial agent responsible for diphtheria. Thanks to the vaccine developed in the 1920s by Gaston Ramon (page in French), a veterinarian and biologist at the Institut Pasteur, diphtheria has virtually disappeared in industrialized countries and many other world regions. But the bacterial infectious agent, Corynebacterium diphtheriae (C. diphtheriae), is still transmitted among the human population, and can cause infection in unvaccinated individuals. If there is insufficient vaccine coverage, as is the case in some crisis-hit regions, outbreaks can soon occur. The critical role of antibiotics in treating diphtheria Treatment for diphtheria involves administering an antitoxin serum and/or a course of antibiotics as soon as possible. But production of the antitoxin serum has virtually stopped at global level. "Antibiotic treatment is crucial for infected individuals and people they are in contact with. Penicillin, one of the first antibiotics to be brought to market, is often still used to treat diphtheria," explains Sylvain Brisse, Head of the Biodiversity and Epidemiology of Bacterial Pathogens Unit and Head of the National Reference Center (CNR) for Corynebacteria of the Diphtheriae Complex. Research into penicillin resistance in diphtheria using CNR strains Resistance to penicillin is currently emerging in the diphtheria agent. Sylvain Brisse's team set out to determine the rate of resistance to penicillin and to understand the origins of resistance in strains of the agent detected in France. "The task of the National Reference Center for Corynebacteria of the Diphtheriae Complex, set up in 2000 following a major diphtheria outbreak in the former USSR, is to collect and characterize strains of C. diphtheriae. The strains collected in mainland France and French overseas territories between 2008 and 2017 were characterized for their sensitivity to 19 antibiotics, including penicillin, and their whole genome sequence was determined," explains Sylvain Brisse. Discovery of a resistance gene Resistance to penicillin was detected in 17% of strains, and multiple resistance (the resistance of a single bacterium to several antibiotics) was observed. A variant of a gene associated with a low affinity for penicillin was discovered, which explains why bacteria with the variant are resistant to the effect of the antibiotic. The gene was found in a variety of genetic lineages of C. diphtheriae, indicating that it can also be transmitted to new lineages. It is sometimes carried by a plasmid, a bacterial genetic element known to carry multiple resistance genes. The plasmid here was newly described in this study. Finally, the authors demonstrated that the gene confers resistance not only to penicillin, but also to several other antibiotics in the same family. These results provide a current snapshot of antibiotic resistance in the diphtheria agent and reveal a new penicillin resistance gene in this pathogen. The findings will help refine the choice of antibiotics used to treat patients and improve diagnosis of antibiotic resistance in diphtheria. More generally, the work carried out by the National Reference Center and its host research unit will provide us with a greater understanding of the re-emergence and spread of diphtheria. Population genomics and antimicrobial resistance in Corynebacterium diphtheriae, Genome Medicine, November 27, 2020 Melanie Hennart1,2, Leonardo G. Panunzi1,3, Carla Rodrigues1, Quentin Gaday4, Sarah L. Baines5, Marina Barros-Pinkelnig1, Annick Carmi-Leroy1,6, Melody Dazas1,6, Anne-Marie Wehenkel4, Xavier Didelot7, Julie Toubiana1,6,8, Edgar Badell1,6 and Sylvain Brisse1,6 1Biodiversity and Epidemiology of Bacterial Pathogens, Institut Pasteur, Paris, France 2Collège doctoral, Sorbonne Université, F-75005 Paris, France. 3Institut Français de Bioinformatique, CNRS UMS 3601, Evry, France. 4Unité de Microbiologie Structurale, Institut Pasteur, CNRS UMR 3528, Université de Paris, F-75015 Paris, France. 5Doherty Applied Microbial Genomics, Department of Microbiology & Immunology, The University of Melbourne at The Peter Doherty Institute for Infection & Immunity, Melbourne, Victoria, Australia. 6Institut Pasteur, National Reference Center for Corynebacteria of the Diphtheriae Complex, Paris, France. 7School of Life Sciences and Department of Statistics, University of Warwick, Coventry, UK. 8Department of General Pediatrics and Pediatric Infectious Diseases, Hôpital Necker-Enfants Malades, APHP, Université de Paris, Paris, France. Farming, Antibiotic, salmonella, salmonelle Scientists from the Institut Pasteur have retrospectively identified early cases of Salmonella resistance to ampicillin, a broad-spectrum antibiotic...
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SKU: 2043574407. Category: Calculator. Tag: Solar calculator. Similar to business card size, ultra-thin, portable, very stylish a product oh. . . We accept the payment by Escrow/Alipay,including Paypl,Credit Card and T/T. 4. Sometimes because of the bad weather or a waste of time in customs clearance. pls wait patiently when you do not receive your item on time. If you don't receive the item , pls contact us, and then I will help you track it. 2.We do not accept the neutral or bad feedback, if you have any question,pls contact with me firstly, we will try the best to solve the problem well.
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Abstraction is a way to make problems or systems easier to think about. It simply involves hiding detail – removing unnecessary complexity. The skill is in choosing the right detail to hide so that the problem becomes easier without losing anything that is important. It is used as a way to make it easier to create complex algorithms, as well as whole systems. A key part of it is in choosing a good representation of a system. Different representations make different things easy to do. For example, when we play cards, we use the word 'shuffle'. Every player understands that 'shuffle' means putting the cards in a random order. The word is an abstraction. The same type of abstraction works when programming. Implementing 'shuffle' in a computer game means giving a way to randomise the cards. We can refer to shuffling throughout the program and understand what is meant without having to think about how it is actually done by the program. All that is needed is that the program does include a description somewhere of how shuffling is to be done. The following links to cs4fn articles that illustrate abstraction. A computer can beat the world champion at chess, even fly a plane more skilfully than a human. How do they do it? How do computers become so clever? [cs4fn-pdf] A perfect, working mind is locked inside a useless body: the sufferer can sense everything around but is unable to communicate with anyone. Locked-In syndrome [cs4fn-pdf] Spend as little time as possible travelling and leaving more for watching whales Watching whales well [cs4fn-pdf] Looking at a picture from your digital camera or a digital movie, it's all just 11001100011– hardly inspiring, and I don't really see what it means! Picture This? JPEG It! [cs4fn-pdf] It turns out though that some missions really are impossible for computers and even Tom Cruise wouldn't be able to make a difference even if he was given unlimited time. Mission:Impossible [cs4fn-pdf] Computer programs look just like a series of rules to control the way cash is moved around. Who wants to be the weakest millionaire? [cs4fn-pdf] How might you go about designing computer judges? Strictly X-Factor [cs4fn-pdf] To be a good computer scientist you have to enjoy problem solving. That is what it's all about: working out the best way to do things. Kakuro, Sudoku and Computer Science [cs4fn-pdf] How is a computer program like a recipe? Paul Curzon explains, and as a bonus, tells you how to cook a quick pasta dish. A recipe for programming [cs4fn-pdf] The code hidden in knitting, and what might happen when computers learn to read it. Knitters and coders: separated at birth? [cs4fn-pdf] If humans are ever to get to like and live with robots we need to understand each other. How to get a head in robotics? [cs4fn-pdf] The emotion machine [cs4fn-pdf] The future of movies and TV isn't film, it's streams of digits. Both are going digital… So what's your favourite MPEG then? MPEG: Movie magic [cs4fn-link] One of the nastiest errors in computer software can come from something called a stack overflow, the computer pops or pushes from its current position, where the stack pointer is pointing, and shoots off the end of the stack, like a magician counting past 52 cards. Johnny Ball's 'Two Wrongs Do Make a Right' Trick [cs4fn-link] Magicians want to move cards around efficiently; computers want to move data around in their memory efficiently. Magical Memories just shuffling along 12 [cs4fn-pdf] When we have to communicate with a computer and give it instructions we want to make life easy for ourselves. tlhIngan Hol Dajatlh'a' (Do you speak Klingon) [cs4fn-pdf] Could you make the most powerful computer ever created … out of chocolates? It's actually quite easy. You just have to have enough chocolates (and some lollies). It is one of computer science's most important achievements. Chocoholic Turing machines [cs4fn-pdf] Use Binary addition to emulate a small-scale feat of memory magic, impressing your friends with your mind's memory power. The mind boggling memory experiment [cs4fn-link] Data compression helps get information small enough to be transmitted quickly, so we can download texts movies and music. Little Data: Compressing Vicky Pollard [cs4fn-link] Rather than having to learn how to use your computers, your computers will have to learn how you would like to use them. Making computers that treat you right [cs4fn-pdf] Using clever computer vision techniques it's now possible for your ingredients to tell you how they should be cooked in a kitchen. Cooking up computer style [cs4fn-pdf] Researchers have come up with a way for people with visual impairment to get more out of images – a method for automatically turning photos of faces into raised pictures that people can feel with their fingers. Fingers feeling focus [cs4fn-pdf] Computers are much better off letting our brains do the tricky thinking. Let the brain take the strain [cs4fn-pdf] An operating system is the software that has direct control of the hardware that applications are to run on. Smart Phones, Operating Systems and Google Android [cs4fn-link] Most computers get round problem of lack of memory using 'virtual memory' hardware. What is virtual memory? It's just a clever way to give the appearance of having more memory than you really do. Raspberry Pi: How do you make a $25 computer? [cs4fn-link] Grace Hopper is famous for more than just the word 'bug' though. She was one of the most influential of the early computer pioneers, responsible for perhaps the most significant idea in helping programmers to write large, bug-free programs. Sorry to bug you: Grace Hopper [cs4fn-link] Humans are great at multitasking so as a cook becomes more confident they start to overlap some of the tasks, checking what to do next while stirring the pot perhaps, or leaving a sauce to simmer while chopping the herbs. Computers do similar things. Ratatouille: Rats doing massively parallel computing [cs4fn-link] Tiny technologies will be able to serve as a window onto the vast world wide web of information, education and entertainment. Gadgets that Change the World [cs4fn-link] In real life, the connection is food, but on the web the connections are links. How nature works like Google [cs4fn-link] When you send an email, ever thought how it actually gets from here to there? Real snail mail [cs4fn-pdf] When pop star Madonna took to the stage at Brixton Academy in 2001 for a rare appearance she made Internet history and caused more that a little Internet misery. Die another Day? Or How Madonna crashed the Internet [cs4fn-pdf] Computer science isn't just about using language, sometimes it's about losing it. Sometimes people want to send messages so secret that no one even knows the messages exist. Hiding in Skype [cs4fn-pdf] You are revamping a hotel and are introducing new card locks rather than ones with keys. Your first thought is to connect all the doors to a computer network. Would that work? Hotel Doors and Keycode algorithms [cs4fn-link] Technology changes society. Whether fire, wheels, guns or skyscrapers, all have made a massive difference to the way we work, live and play. Computer technology is accelerating the change and raising whole new issues society has to tackle. The FUNdamentals of Computers and Society [cs4fn-link] Since the advent of the microprocessor by Intel in 1971, electronic computers have made their way into more areas of our everyday life. It is now unlikely that most people in the developed world will get through a day without some use of a computer. So what are the impacts of this technological revolution which benefits and detriments our society? So What's the Problem? The Impact of Computers [cs4fn-link] With more and more opportunity to tell the world your stories, through web blogging, or networking sites like myspace and youtube, there are so many tales being told, but which of them are true and which of them made up. Peer into science – It makes a good story [cs4fn-link] Social scientists have found that people don't always help others, even if they realise someone's in trouble. The only way to figure out why this happens, and what makes a difference whether bystanders help someone, is to study situations like it. But how? Scientists can't just go around beating people up to see how others will react. Stirring up virtual trouble [cs4fn-pdf] More of our resources, including linked computing 'story' booklets can be found in our resources section. You may also want to look at cs4fn's teacher resources or browse the latest cs4fn magazine. It is suggested that: Primary teachers focus on the badge statements from the Pink to Purple row. Secondary teachers focus on the badge statements from the Purple to Black row. The white row overlaps with the KS4 qualification specifications.
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package safehtml import ( "encoding/json" "fmt" "regexp" ) // A Script is an immutable string-like type which represents JavaScript // code and guarantees that its value, as a string, will not cause execution // of unconstrained attacker controlled code (cross-site scripting) when // evaluated as JavaScript in a browser. // // Script's string representation can safely be interpolated as the // content of a script element within HTML, and can safely be passed to DOM // properties and functions which expect JavaScript. In these cases, the Script // string should not be escaped. Script's string representation can also be safely // used as the value for on* attribute handlers in HTML, though the Script string // must be escaped before such use. // // Note that the Script might contain text that is attacker-controlled but // that text should have been interpolated with appropriate escaping, // sanitization and/or validation into the right location in the script, such // that it is highly constrained in its effect (for example, it had to match a // set of allowed words). // // In order to ensure that an attacker cannot influence the Script // value, a Script can only be instantiated from compile-time // constant string literals or security-reviewed unchecked conversions, // but never from arbitrary string values potentially representing untrusted // user input. type Script struct { // We declare a Script not as a string but as a struct wrapping a string // to prevent construction of Script values through string conversion. str string } // ScriptFromConstant constructs a Script with its underlying script set // to the given script, which must be an untyped string constant. // // No runtime validation or sanitization is performed on script; being under // application control, it is simply assumed to comply with the Script // contract. func ScriptFromConstant(script stringConstant) Script { return Script{string(script)} } // ScriptFromDataAndConstant constructs a Script of the form // // var name = data; script // // where name is the supplied variable name, data is the supplied data value // encoded as JSON using encoding/json.Marshal, and script is the supplied // JavaScript statement or sequence of statements. The supplied name and script // must both be untyped string constants. It returns an error if name is not a // valid Javascript identifier or JSON encoding fails. // // No runtime validation or sanitization is performed on script; being under // application control, it is simply assumed to comply with the Script // contract. func ScriptFromDataAndConstant(name stringConstant, data interface{}, script stringConstant) (Script, error) { if !jsIdentifierPattern.MatchString(string(name)) { return Script{}, fmt.Errorf("variable name %q is an invalid Javascript identifier", string(name)) } json, err := json.Marshal(data) if err != nil { return Script{}, err } return Script{fmt.Sprintf("var %s = %s;\n%s", name, json, string(script))}, nil } // jsIdentifierPattern matches strings that are valid Javascript identifiers. // // This pattern accepts only a subset of valid identifiers defined in // https://tc39.github.io/ecma262/#sec-names-and-keywords. In particular, // it does not match identifiers that contain non-ASCII letters, Unicode // escape sequences, and the Unicode format-control characters // \u200C (zero-width non-joiner) and \u200D (zero-width joiner). var jsIdentifierPattern = regexp.MustCompile(`^[$_a-zA-Z][$_a-zA-Z0-9]+$`) // String returns the string form of the Script. func (s Script) String() string { return s.str }
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Adani wanted names of CSIRO scientists - Deputy Prime Minister Michael McCormack says he understands why Adani wanted the names of ... Our Lady of Mercy Catholic School B4 Program Thu 18 Jul 2019 09:30 am to 11:00 am Our Lady of Mercy Catholic School, Deloraine Our Lady of Mercy Catholic School in Deloraine is running a FREE Birth to 4 program, held at the school every Thursday during term time between 9.30 and 11.00am. Our B4 Program is open to all children who haven't yet started school – just bring a hat and snack and come along for lots of fun and learning. For more details about Our Lady of Mercy's Birth to 4 Program, please contact the school on 6362 2323 – and check out their Facebook page!
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NASHVILLE, Tenn. (MAY 23, 2018) — GRAMMY® nominee, Dove Award winner, and Capitol recording artist Danny Gokey is gearing up for his first-ever headline tour with this fall's Hope Encounter. Also featuring GRAMMY® nominee Tauren Wells and breakout artist Riley Clemmons, the tour will hit 29 markets across the country, including Los Angeles, Atlanta, Seattle, Phoenix, Oklahoma City, and more. Produced by general market powerhouse Outback Concerts, the tour will play mostly theaters and performing arts centers. For tickets, please visit www.dannygokey.com. Hope Encounter tickets pre-sale takes place Tuesday, May 29, with an email push to Gokey's fan list. Venue pre-sales launch in each market at 10 a.m. (local time) on Wednesday, May 30. National on-sale date is Friday, June 1, at 10 a.m. local time. His latest album,?Rise,?reached #1 on the Billboard Top Christian Album chart and garnered his first GRAMMY® nomination.? Its title track, marked his third multi-week, multi-chart #1 single. Tauren Wells, a four-time GRAMMY® nominee, debuted Hills and Valleys — his first full-length solo project — in July 2017, just prior to hitting arenas on the Lionel Richie/Mariah Carey 22-city "All the Hits Tour." The album's title track was one of the most streamed Christian songs of 2017, according to Spotify, and currently registers over 50 million total streams. The official music video and lyric video have combined views exceeding 25 million. His single, "Undefeated," also served as the soundtrack for the internet-famous Dude Perfect's "World Records Edition" episode on YouTube which, along with another Dude Perfect video featuring the No. 1 single "Love Is Action," has garnered more than 100 million views combined. Wells made history earlier this year by landing singles in both the #1 ("All My Hope (ft. Tauren Wells)" by Crowder) and #2 ("When We Pray") spots simultaneously on national radio charts. Riley Clemmons is an 18-year-old, Nashville-based singer/songwriter signed to Capitol Christian Music Group. Her debut single, "Broken Prayers," skyrocketed at radio upon its release in early 2018 and the music video earned over a million views on YouTube in less than two months. The single has now crossed over ten million global streams. Most recently, Riley was featured on the song and music video for Social Club Misfit's radio single "Misfit Anthem" and mainstream DJ, Tritonal's "Out My Mind." Her upcoming full-length debut album releases August 3, 2018. Click HERE to view the official tour trailer. *Dates subject to change without notice.
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New Jersey high school principal dies after donating bone marrow to save stranger Posted: Apr 11, 2019 / 11:10 AM EDT / Updated: Apr 11, 2019 / 11:10 AM EDT WESTFIELD, N.J. – A high school principal died after going to the hospital to donate bone marrow to try to save the life of a 14-year-old in France. Derrick Nelson, principal of Westfield High School in New Jersey, died unexpectedly Sunday night, according to school officials. His fiancée, Sheronda Braker, said that Nelson suffered complications after his bone marrow donation. The school's newspaper reported in February that Nelson decided to donate his bone marrow to a boy in France after being contacted by Be the Match. The national bone marrow donor program told him that his blood might be a match. "If it's just a little bit of pain for a little bit of time that can give someone years of joy, it's all worth it," Nelson told the paper then. In a statement to CNN, Braker said Nelson "was a tremendous father to our beloved daughter Morgan and the best companion and life partner I could have ever asked for." "He loved his family almost beyond belief. He was a man who carried himself with dignity, courage and compassion," she continued. "His last kind and generous act on this earth in giving so someone else might live is a true testament to who he was and how he should always be remembered. We will always love him." in a letter to parents, Westfield Public Schools Superintendent Margaret Dolan said, "Dr. Nelson touched us all with his kindness, compassion, integrity, and endlessly positive attitude. "We hold him and his family in our hearts as we grieve this loss together and I know you join me in granting his family the privacy they have requested." Nelson, 44, served in the US Army Reserve for more than 20 years, according to Dolan. He joined Westfield Public Schools in 2010 as the assistant principal of Roosevelt Intermediate School. He later was assistant principal and principal of Westfield High, which has more than 1,800 students. People praised Nelson as a committed educator and a role model with a strong moral compass. His friend Salim Sivaad, also known as Wayne Clemmons, an Atlanta-based musician, told CNN he received news of Nelson's death from a mutual friend. "Derrick was my brother's college roommate and fraternity brother, and that's how I met him back in 1995," he said. "I had not been in contact with him recently. That's why it was such a shock. ... I didn't know he was donating or had the complications before he passed." Jackson O'Brien, senior class president at Westfield High, told CNN affiliate WABC, "He always tried to inspire students in the classroom and outside to be good people. And I think he served as a great role model." Westfield Mayor Shelley Brindle said on Facebook that her family was "devastated" to hear the news. "This is a tremendous loss for our community, and I know that our children, and we as parents, will struggle with coming to terms with this over the coming days and weeks," she said. "He was a man of immense character and kindness, and his legacy will live on in the generations of students whose lives he touched." New Jersey Gov. Phil Murphy called the principal's final act "one of selflessness." by FOX59 Web / Jan 19, 2021 BARTHOLOMEW COUNTY, Ind.-- The Bartholomew County Sheriff's Department announced the arrests of four people from Morgantown on drug-related charges Sunday. "Drugs destroy families and communities," said Bartholomew County Sheriff's Major Chris Lane. "JNET and your Bartholomew County Sheriff's Office will continue pursuing those who distribute and abuse dangerous drugs in Bartholomew County." INDIANAPOLIS — The Indiana State Department of Health (ISDH) reported 2,756 more positive coronavirus cases and announced 126 additional confirmed COVID-19 deaths Tuesday. The latest ISDH dashboard data indicates the state's 7-day all-test positivity rate of 11.9%, with a cumulative rate of 10.8% positive. 3 million virus cases reached in California; first state to cross that threshold Local political expert talks about Inauguration Day preparations President-elect Biden makes history with asst. health secretary pick, names transgender woman to the role National & World / 2 hours ago
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YES does not touch or interfere with roof and roof line. YES The hood and gutter are made of the same material and color. NO – Product designed to go on existing gutter-original house and roof design does not incorporate supplemental product. NO – Tries to match color of existing gutter. MAYBE – Product goes on existing gutters-if you have leaky, rotten gutters before product is installed, you will still have them. See what folks are saying about K-Guard!
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You are looking for popular searching results for Long Shift Dress - Shop sales, stores & prices - Get the best sales, coupons, and deals on Long Shift Dress at GoByDeals.com as seen on April 18, 2019. Find TOP Promo-codes for Long Shift Dress from Every US Store at GoByDeals.com Store. Shop The Best Long Shift Dress with Fast and Free Shipping to U.S. of America, UK, Canada, Europe, and Australia in GoByDeals.com Store. GoByDeals Suggests Browning Big Game Fleece, Baylor Bears Pillow and 1950 Sport Magazine - Order Online at Amazon, Walmart, Ebay. Enjoy shopping for discount prices? Want to compare prices on gift ideas online before making a purchase? Looking for ways to save money? All of this and more is possible at GoByDeals.com - your premier source for online comparison shopping: compare prices on 300 000+ products from leading online stores WayFair, Target, OverStock, Etsy, Macys, Lowes, HomeDepot, BestBuy, and others. GoByDeals is the leading price comparison online service for discount shopping: start searching & find the best popular items at cheapest prices. Bring your Long Shift Dress ideas to life with our fun tools and exclusive styles. © Long Shift Dress Discount Shopping at GoByDeals | Last Checked Shopping Results on April 18, 2019 | Sitemap.
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The Daytona International Speedway is one of the world's greatest race tracks. Host to countless events, one of them is the annual 4th of July NASCAR race under the lights – NASCAR's Xfinity series and Monster Energy NASCAR Cup Series take to the track for night races at one of the fastest tracks on the circuit. Fans pack in the stunning facility that has been modernized in recent years to watch some of the most exciting racing in all of America. There is plenty to eat at Daytona in the paddock and beneath the grandstands in the main concourses. From drinks, coffee, and traditional stadium fare to more eclectic choices, the variety is impressive. During the race weekend, there are also a variety of places to get food throughout the infield – from the arepa stands around the main walkways to the Bud Bar, you will never have any issues finding something to eat. Options are varied and made with quality food. The Pastrami Swiss Burger is a popular twist on the stadium favorite, costing just $10. The track also offers a gouda stuffed veggie burger for $8, or a fish & chips sandwich for $9. Hawaiian chicken sandwiches run $10, while a hot dog costs just $5. Soda and water run from $4 to $5, with beer costing $8 or $9. The race itself is one of the biggest races in NASCAR. Everyone looks forward to going to Daytona for its close racing and exciting action, but putting that same action under the lights just adds another aspect of brilliance to an already thrilling experience. The facility is stunning already, and the massive 2.5 mile racetrack features a modern fan zone on the infield that gives fans an unparalleled up close view of the teams, cars, and even the inspection areas. The grandstands feel like a professional sports stadium thanks to the Daytona Rising renovation of the last few years. Each seat is an individual backed chair, meaning the days of cramming onto a bench with no back are over. You can sit in comfort and enjoy the action. To top it all off, you won't miss any of the pit stops thanks to your proximity to pit road. Your elevated position gives you a great view of the pit stops during the race, and the big screens along pit road also let you see the replays after each key moment in the race. Daytona is a party town from days gone past, when tourists flocked to the beaches during the summer months. However, the sun isn't always so warm in North Florida in January. Nonetheless, the beaches are still just a few miles away from the track. In addition, right across the street from the track sit numerous stores, malls, and restaurants. From Chipotle and Panera to Olive Garden and Longhorn Steakhouse, there are plenty of places to shop and eat during your stay. The closest hotels include an Extended Stay America and a WoodSpring Suites Daytona. For attractions, historic Daytona Beach is just a few miles away, and an hour south you can find Kennedy Space Center. NASCAR fans pack in Daytona to see the action, including the campgrounds in the infield. They cheer loudly for their favorite driver and against the rest. NASCAR fans are among the most loyal in sports and some of the most sport knowledgeable. That said, they also love their alcohol and rebel flags, so the infield may not be the best place for kids during race weekend. Aside from that, expect one of the most incredible sports experiences around when you have roaring crowds on their feet for 160 laps. Parking at the track is plentiful – not only are there on-site parking lots for various types of parking passes, the track hosts numerous off-site parking options for fans to use, as long as you're willing to walk. For those who would rather take a ride, trams are also available to shuttle you in and out of the facility from the off-site parking lots, as well as to take you from one point to another at the track itself. You also can wander the facility as you wish, with any ticket granting access to the stadium grandstand seats as well as the infield fan zone. The track itself is located right off I-95 (you can see the track from the highway). It is hard to miss the massive facility, but just in case, there are tons of street signs pointing the way. Tickets can get pricey for NASCAR races, but Daytona offers plenty of pricing options for fans at every level. From individual tickets to weekend passes, you can fit getting to Daytona International Speedway into every budget. With the cost of concessions rather affordable as well, you can go to the races here without breaking the bank. The track features a massive fan area both in the infield and at the outside entrances, both of which are full of vendor displays and giveaways. You can also tour the Daytona USA museum during your visit for an added cost. In addition, each ticket gets you into the garage and paddock area at Daytona, and you can see fantastic views of the track and the paddock from the rooftop patio decks. Fans can also get a look at the team preparations, thanks to the viewing windows in each garage bay. Fans can also look forward to the autograph sessions throughout the weekend – the Xfinity series drivers usually hold one on Friday afternoon in the infield fan zone before the race begins. The racing at Daytona is among the best in racing – the facility is top notch, and the track has history around every corner. No matter what you are into, this is a sports experience that begs to be seen. Furthermore, night racing at Daytona International Speedway seems to take everything that is great about day racing and amplifies it. The colors, the sounds, the roar of the fans; all of these combine to make one great experience for fans.
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The Hawaii Department of Transportation (HDOT) has confirmed that Transportation Network Companies (TNC) will be eligible to pick up customers at neighbor island airports from February 1, 2019. Designated rideshare pick-up locations at Kahului Airport (OGG), Lihue Airport (LIH), Ellison Onizuka Kona International Airport at Keahole (KOA), Hilo International Airport (ITO) and Kapalua Airport (JHM) have been established by HDOT. Amended administrative rules went into effect in August 2018, enabling TNCs to apply for a permit from the Hawaii Department of Transportation. The rules were approved following public hearings. This was the first time the rules for commercial services at airports had been amended since 2002. Interested in ride sharing and other types of transport connections? Check out the 'Airport Cities, Transport Connections & Regions' stream at the Passenger Terminal Conference, which takes place during Passenger Terminal Expo, on March 26, 27 and 28, 2019, in London.
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Country music 'Storyteller' Tom T. Hall died by suicide, medical examiner says Matthew Leimkuehler Cole Villena Tom T. Hall, a Country Music Hall of Fame artist known as "The Storyteller," died over the summer by suicide, according to the Davidson County Medical Examiner, which conducted an autopsy on the late singer-songwriter. Hall died Aug. 20 at his home in Franklin, Tennessee. He was 85. Saving Country Music, a country music website, first reported Hall's cause of death Wednesday afternoon. Born May 25, 1936, in small-town Olive Hill, Kentucky, Hall was a consummate country songwriter who captured life's intimate details with songs such as "I Like Beer," penned the classic "That's How I Got To Memphis" and showcased era-defining sharpness with "Harper Valley PTA." Hall entered the Country Music Hall of Fame in 2008, alongside Emmylou Harris, The Statler Brothers and Ernest Stoneman. Tom T. Hall:Tom T. Hall, 'The Storyteller' of country music, dies at 85 Throughout his career, Hall timelessly and empathetically chronicled humanity — from barstool stories to cemetery caretakers — with tales that would influence generations of wordsmiths to follow. His songbook of country hits includes "(Old Dogs, Children and) Watermelon Wine," "A Week in a Country Jail," "I Love," "Little Bitty," made famous by Alan Jackson ... and the list goes on. Many in country music called him "The Storyteller," a nickname given to Hall by another country great — Tex Ritter. If you or someone you know may be struggling with suicidal thoughts, you can call the U.S. National Suicide Prevention Lifeline at 800-273-TALK (8255) any time day or night, or chat online. Crisis Text Line also provides free, 24/7, confidential support via text message to people in crisis when they dial 741741.
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Politics, War Palestinians Growing Nostalgic for Glory Days of Jordanian and Egyptian Occupation by Danny Nash © Rrodrickbeiler | Dreamstime.com - Palestinians Protest Gaza Attacks Photo With the world now witnessing the forty-ninth year of Israeli control over parts of the West Bank, Palestinian residents of the territory are beginning to feel pangs of nostalgia for simpler times. Most people feel nostalgia for things like the Power Rangers, or Super Nintendo, or freedom from the crushing realization that time marches ever forward while affording you fewer and fewer chances to accomplish the things you've always wanted to. But recent reports coming out of the Palestinian Territories of Gaza and the West Bank have revealed that residents have begun to yearn for the good old days of being occupied by Egypt and Jordan, respectively. "Most people forget that we were occupied by Egypt and Jordan," one West Bank resident told The Mideast Beast. "But for nineteen years, from 1948 to 1967, we lived under Jordanian occupation, while our brothers in Gaza were ruled by Egypt." RELATED: Choose Your Own Narrative Yes, it seems like the pre-Israeli occupation has faded from the international community's collective memory just like the Baha Men, or the Matrix sequels. "Simpler times," recalls the West Bank resident. "We didn't worry about statehood back then…we had it better than the Gazans, to be sure – but when is that not true? Yet then, the Jews came for us like dogs, and we asked, 'Who let the dogs out? Who? Who?' In 1967 we got new occupations that were just sequels way worse than the originals. Or were they?" Iranian Official: "We Would Have Given Up Nuclear Ambitions If Obama Had Gotten A Better Deal" U.S. to Flip a Coin to Decide Which Side to Support in Syrian War Report: United States to Possibly Supply Iran With Nukes
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Public notices provide citizens with important information about how government performs its work. Virginia's public notice laws require government, businesses and some individuals to give notice to the public when critically important actions are about to be taken – the foreclosure of a home, passage of a local ordinance, the building of a new highway, the adoption of a child – and so on. Newspapers (print and digital) provide a reliable, accessible way to reach the public. VPA has created a statewide public notice website to provide greater access to public notices in the Commonwealth. The website is keyword searchable, archived and free to use. The Virginia public notice process requires governments to work with newspapers to guarantee that notices are published with the correct frequency and on time and that all notices are archived. To learn more about the process – see our Public Notice Overview. How to promote publicnoticevirginia.org through house ads.
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Peripheral Hospitals Emergency Medicine Conference Inc. (PHEMC) is a non-profit organisation dedicated to Emergency Medicine education and training. Its annual Spring Seminar on Emergency Medicine is a family friendly and relaxing event, and is now one of the major Emergency conferences in Australasia. PHEMC also organizes, in conjunction with ACEM (NSW), the Evidence Review on Emergency Medicine. Held annually in Autumn, the Evidence Review is a concentrated meeting with an emphasis on review of current scientific literature and research. In 2016, we introduced the GEM Seminar to great success and we hope to continue this annually. PHEMC collaborates with ACEM, ASCMO and ASEM to ensure that its conferences are both at the forefront of scientific education and also relevant and accessible to all emergency medicine practitioners.
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"Violence is wrong," say gamers, "unless it's funny." Posted on September 30, 2011 by Syp As we're probably all aware, video game culture — the games themselves, the players, and the media covering it — has a wee bit of an image problem. No matter how far we've progressed in becoming more mainstream, trumpeting video games as art forms to Roger Ebert, and helping to cure AIDS through gamer groupthink, we've yet to shrug off this massive reputation of being immature jerks. Some days, like today, I can see why we're spinning our wheels with progress in this regard. If you haven't heard already, there's this story of a middle-aged dad in the UK who was taunted by a teenage kid over Xbox Live, so he tracked the kid down and choked him. Not to death, but bad enough that it freaked the family out and ended with an arrest. It's a story that's lit up discussions all over the place, mostly due to so many people — wait for it — applauding the choker for his actions. I'm not even remotely making this up. Gamers far and wide are applauding this physical assaulter because he represents "sweet vengeance" or something on smacktalking video game jerks. What gets me, when reading reactions to this story, is just how petty and vindictive these comments are. Plenty of them start with "I don't condone violence, BUT this kid was asking for it." Because violence is bad, you know, unless it's either funny or provides some sort of vicarious release for gamers who sometimes fantasize about slapping online jerks upside the head. I get that. We all have those daydreams, especially when someone is just mean, rude or vile to you and you feel like you can't do anything about it. The thing is, having fleeting dark revenge fantasies is legal. Physically trying to kill someone is not. No matter how much you think this kid "deserved" the payback, words don't justify assault. It's when gamers are coming to the defense of the choker that I realize the mob is no better than he. He just did what they wanted to, and they're cheering him on for it, all while making noises about understanding that it wasn't really right and hiding behind the shield of "it's FUNNY so stop taking it so seriously!" No, it's not funny. It's sad and kind of sickening. There's a lot of other side issues in this topic, such as the fact that this guy is clearly unstable, the kid's parents should've been monitoring their son's online behavior, and that if this teen was griefing this guy, there were plenty of ways to avoid/block/blacklist him so as to not have to deal with him from then on. I understand the kid and the parents aren't blameless, but none of this excuses the guy's actions, and gamers do no credit to their community by trying to provide justification just because of their own personal frustration at griefers. Seriously, how can we act like we're maturing when this sort of thing goes on? It's good to read statements and discussions by those who weren't rooting for the choker and realize that this gives a black eye to the games community, and that's heartening. I just wish I had read more of them today. September Survey Results This monthly what-MMO-are-you-playing survey isn't anything remotely scientific or probably fair, but I'm just curious what Bio Break readers are playing and wanted to get a finger on the current gamer pulse, so to speak. So without further ado, the top ten (which is actually more like top 15 with the ties): Lord of the Rings Online (127 votes) [tie] World of Warcraft and RIFT (68 votes apiece) Guild Wars (37 votes) [tie] EverQuest II and City of Heroes (25 votes apiece) Champions Online (23 votes) EVE Online (19 votes) [tie] Age of Conan and Star Trek Online (17 votes apiece) Fallen Earth (14 votes) [tie] Warhammer Online and Dungeons and Dragons Online (11 votes apiece) [tie] World of Tanks, Star Wars: The Old Republic beta, Aion (6 votes apiece) By and far, LOTRO had the most votes, which you can chalk up to (a) its continued popularity, (b) this month's expansion, and (c) a good chunk of LOTRO fans who read this blog. Take your pick. RIFT and WoW are battling for the #2 spot, and Guild Wars has a decent third place showing (are people trying hard for their Hall of Monuments points, like myself?). I'm most surprised to see Warhammer Online on the list, since I'd long assumed that fell out of favor, but hey, that's cool! Champions is another shocker, a mere couple of votes down from City of Heroes (and way, waaaay above DCUO). Out of this list of 15 titles, one is in beta, one is buy-and-play forever, seven are F2P or have F2P options (with two more about to make the switch — Fallen Earth and STO), and the rest subscriptions. Other interesting results: No readers play RuneScape? At all? DCUO and EverQuest tied for a measly 3 votes apiece… I don't know if that's sadder for EQ or DCUO. 3 votes of "None" 3 votes for FFXIV, so apparently some people are still playing it! Cool to see write-ins for a wide variety of titles, including DAoC, Vanguard, Star Wars Galaxies, Runes of Magic, Dragon Nest, Forsaken World, Vindictus, Anarchy Online, WURM Online, Hellgate, Perpetuum, Eden Eternal, League of Legends, Puzzle Pirates, Need for Speed: World, Star Legends, Age of Empires Online, Global Agenda, Free Realms, and Pirates of the Burning Sea It'll be interesting to see what next month brings! Bio Break September MMO Survey! The Curious Case of Final Fantasy XIV Posted on September 28, 2011 September 28, 2011 by Syp We haven't spoken of Final Fantasy XIV around these here parts since late last year, when I awarded it "Dud of the Year" with a slightly guilty feeling. Actually, I'm hard-pressed to think of any blogger who's even mentioned playing it within the last eight months, apart from Massively's Eliot. Eliot brought to my attention the fact that FFXIV is just now hitting its first anniversary, which Square-Enix celebrated by saying that the game "greatly damaged" the Final Fantasy brand. Ouch. Ever since the game launched in complete shambles, Square-Enix has been scrambling to make it right — somehow, anyhow. Every once in a while I hear about patches and fixes, but it's safe to say that the FFXIV buzz in the MMO community is somewhere around flatline. It just doesn't exist. But what I didn't realize is that for this past year, the game's been entirely free, since SE is not confident enough in its product yet to flick on the subscription switch. I knew it was free for a couple months following the launch, but still? A year later? How much money is FFXIV losing the company on a monthly basis? And what will the company do from here? The first option is to get the game to a much, much better point than it was at release, throw a relaunch party of sorts, and pray that players stick around — and that others come check it out. The second option, of course, is to go free-to-play and introduce some sort of microtransaction business model to help fund the project. Pulling the plug entirely would be a PR disaster for Square-Enix, especially since it's a major part of the Final Fantasy series — Roman numerals and all. I've often been baffled by Square's business practices, especially in the MMO field, because I get the feeling that the devs and corporate suits are too far removed from the rest of the industry at this point and unwilling to change that. Maybe things are finally getting better. But something's going to need to be done with FFXIV sooner or later before it becomes a money pit from which there is no escape. LOTRO: Running with the deer After a lengthy ordeal involving me, the LOTRO patcher, and a police stand-off, I finally got Rise of Isengard loaded onto my computer and logged in to experience the wonder and majesty of… crap, did it just crash? It did, didn't it. It wasn't the smoothest launch day, to say the least. But when the dust settled and I got in, there was enormous fun to be had. Our kinship was overflowing, the GLFF channel was scrolling by so fast, and I barely knew where first to go. Since LI points had been reset, I spent some time working on those and figuring out where all my skill buttons went (since several skills got consolidated). Once everything got sussed out, I headed down into Dunland after a completely unnecessary Book 4 intro detour into a part of Enedwaith that is tedious to travel to and didn't really need to be visited other than to high-five a quest giver and leave. Rise of Isengard offers you the choice of one of two starter clans to help out, so I went with the Clan of the Stag and spent the evening wrapped up in their plight. I don't know if Enedwaith was just so substandard or if I'm way into the expansion vibe, but I got completely sucked into the story being told there. It wasn't just Generic Quest Hub #164, but a village with a real tale to be told… and even though I was incredibly tired, I stayed up as late as possible to help them out. I'm pretty psyched to get back home today and play. I can already tell that LOTRO is going to dominate my gaming time for a while to come, and that's just fine — Guild Wars and Fallen Earth will be there when I get back. I'm surprised just how fast the XP was coming; after just a couple hours of play, I'd already gained a half level and seen plenty of folks hit 66 and 67. One kinnie actually saved up a full quest log of turnins to get a jump on the "race." Good stuff. Loving the new armor and the additional stories — hope this feeling continues throughout the expansion! Glory of glories, it's expansion day! As I write this, the heavens are pouring down rain and the lighting scheme in my office is something akin to "serial killer cavern." It's a dark and gloomy day, is what I'm trying to say. But oddly enough, it's a good day, a GREAT day. Why? Because when I go home tonight, I have a brand-new Lord of the Rings Online expansion to explore: Rise of Isengard. I've actually refrained from touching LOTRO for a good week or so now. I tend to do that right before game expansions, because I like to build up the anticipation some more as well as have a break so that my batteries are fully charged. I did log in last night to make a new outfit for my Lore-master and buy him some consumables, but that was it. I'm ready. My excitement isn't exactly bubbling over, it's just at an elevated rate. I really do wish there was something I was so eager to see or do or experience that I'll be rushing at like a newly opened theme park ride. Instead, this all feels like a solid addition that will be filling in the long run. I'm looking forward to tonight's excursion, because expansions always bring out friends and kinnies in droves. General chat channel talk spikes up as well, as everyone wants to share their experiences with others. My plan is to approach this expansion with a laid-back, steady sense of exploration. It's cool that there are two "starter" towns for Dunland to both give players choice and spread out the populace somewhat. This may be defeated by the fact that the westernly one is a bit more off the beaten track than the eastern one. After a long, long wait, players can progress their characters upward and onward: ten new levels, 2 more ranks per virtue, new skills, better armor, etc. I'm not thrilled about having to level up 12 virtue ranks, but I won't be in much of a rush to do it anyway. Instead, I'm more interested in seeing how my character functions with the class tweaks, and to be hunting down all of the new armor designs for my outfits. I'm going to have to keep an eye out for the next tier of legendary items, too. And crafting! Oh, the crafting! In short, not going to be bored any time soon. So happy expansion day to my fellow LOTRO players! Enjoy and see you in game! Posted in Star Wars: The Old Republic On the fifth day before Christmas, BioWare gave to me… …a Wookiee in a pear tree! So on a Saturday, of all days, BioWare finally announced the two big details everyone was waiting to hear: When and How Much? The When is December 20th (or 22nd in EU), and the How Much is $15/month with discounts for multi-month orders. Obviously, big, big news, although it's certainly not going to satiate any SWTOR fan's desire for more info (for instance, when does the early access start)? Anyway, let's break it down: BioWare's obviously concerned about pulling a World of Warcraft with its launch — i.e. having too many people try to jam through the door at the same time, servers crashing, people unable to log in. A bad launch day is something players tend to remember and hold over a company's head forever, so it's pretty imperative that this not happen. So we're seeing a multi-stage rollout: first the early access folks with the pre-orders, then NA, then EU. Within that, BioWare's stated that it has no compunctions against throttling access during this period to ensure that those who do get in aren't subject to a horrendous experience. December 20th is an interesting pick for a launch date, I'll admit. I honestly thought it'd be a little before this, perhaps December 10th or so, but the 20th accomplishes a few important deeds. First, it hits the targeted "Holiday 2011" mark. Second, it gets the game out the doors before Christmas, although just barely (and I feel bad for the BioWare staff that will undoubtedly have to work through the holiday season to troubleshoot and monitor everything). Third, it makes this the "must play" game of the season, particularly in the weeks afterward where there's traditionally little else to compete for attention. Finally, it gives BioWare as long as possible to polish up the game without crossing the Christmas barrier. For many people, it's better to have a date than to be left wondering, but now players have to cope with the reality that we have a three-month (minus a couple days) wait in front of us instead of the hope that, hey, it could come out on Halloween or something. It's a good chunk of the year to wait, but speaking as a player who deeply values a finished product over something rushed out the door early, I'm all for giving BioWare this time. I just hope that they get more of the beta test weekends going and soon, so that the feedback can be incorporated into the launch product. I really thought we'd be seeing a little something different with the subscription cost — perhaps a higher per-month charge, or a strong emphasis on an in-game store, or whatever. But no, it's pretty standard: $15/month, $42/3 months, $78/6 months. As always when studios offer this variety, it's up to players to weigh the potential benefit of a few dollars saved versus locking into a longer time frame. I am happy it's not more than $15 a month, and I think it's smart, because it puts SWTOR on war footing with WoW. One thing to note is that we didn't see anything in regards to either special pre-order pricing (I like what LOTRO and RIFT did with that) or lifetime subscriptions. I wasn't really expecting it, but still, it would have been nice to have more options. Posted in Quote of the Day "If your a woman with a scar, or missing limb, you can kiss your romantic life good buy." ~ Massively commenter The more I read this quote, the more I'm hypnotized by its layers. If you were to ask me — and I'm not suggesting for a minute that you would do so, since you're a busy man/woman/intergalactic parasite — what my most anticipated aspects of Star Wars: The Old Republic are, I'd most definitely put "companions" in the top five. Easily. I know some people are not on board with the concept, but I'm willing to be 100% self-centered in this regard and go, "WOO! It makes me happy, baby!" After all, I've always loved pet classes, crave non-combat pets, and vastly enjoyed the array of BioWare companions that the company's created for their various single-player RPGs. They do live up to the word "companion," because they've provided an artificial but still meaningful feeling of companionship during my journeys. I'm much more likely to remember companions and their related stories from those games than the other aspects of the games' stories, which is a testimony to the storytelling power that these characters can bring. I think that the boon of companions is something that can't really be felt out in the many quick impressions that people are getting from conventions and beta testing weekends, and thus might be vastly undervalued until people start playing for keeps. I know there's worries that "hey that guy has my companions and thus I lose that unique spark" and all that, and while it's understandable, I don't think it'll be as big of a deal in the long run. I like that BioWare's not only including appearance kits so you can make your companions look different, but that the team's removing the names of companions over their heads when you look at other players and their little friends. It's a small touch, but it'll help to shore up the illusion that we're all special snowflakes. Gamespot posted a new 7-minute dev diary about the companion system, and it just flew by when I watched it, it was so good. You can tell that the devs know not everyone's sold on companions, but that they're confident enough in their place in the game that they're going to put them out there and trust that they will catch on — and even be a watercooler topic for some. I agree that Blizz looks like one of the coolest characters ever — a Jawa with a rocket launcher(!). If you're not allergic to spoilers, several sites already have the full list of all 40 companions (5 per class, plus a ship droid per faction) for quick perusal. Five seems like a good number, particularly when you consider that you can only take one with you on any given excursion. It's enough that you could switch up a new companion every night for most of the week and get a different experience each time. BioWare promises that companions are more than mere pets, and I can see what the team is trying to do here. In addition to providing storytelling moments and feedback on your character's decisions, they can participate in crafting (and crafting quests), get into romances with you (I'm betting each class has just one romance option per gender, so two out of the five), unlock special companion quests, and — perhaps most importantly — shore up your character's weaknesses with their strengths. An example shown in the video was of a ranged Force user who teamed up with a melee tank companion to keep the bad guys off of his back while he worked his mojo. The "gift" system from Dragon Age, etc., is back, and it's both appreciated and unfortunate. Gifts are basically a way to buy influence points with your companions if you treat them like crap or do actions that they disapprove of. On one hand, it lessens the consequences of your choices if you don't have to live with the fallout of what you've done. On the other hand, this frees players up to actually choose what they want instead of what they think they HAVE to do to appease their companions. I guess that having to shell out money for the gifts is a form of consequence, when you think about it. Companions might be such a huge draw after the launch of the game that new ones will be in high demand — and could up the replay value of classes. Heck, I can see even going through the same class twice, choosing wildly different choices and engaging with my companions in different ways, just to see what happens. We typically do that for most BioWare titles anyway. In any case, I know I'm going to have to eventually experience all eight classes, if nothing else than to see all of the companions and get to know them. Looking at the scope of that, SWTOR could be the beginning of a long and beautiful friendship. Posted in Guild Wars Waiting for launch? Give us something to do! Yesterday I finished up the Guild Wars Factions campaign, marking the length of this journey so far around a year or so. It's a nice feeling of accomplishment, coupled with the realization that I'm finally making real progress on my Hall of Monuments (and can, y'know, actually see said Hall pretty soon). I'm trying to suss out how I can get two more titles without a huge amount of time and effort, but I don't see any shortcuts presenting themselves. It's either grind or time at this point. That's probably fine, since it's not like Guild Wars 2 is beating down our door here. One step at a time and you can walk around the world, although the wet stuff is probably going to impede your progress. Looking over Hall of Monuments details last night got me thinking about just how much I appreciate having something — anything — to do in preparation for an as-of-yet unreleased title. Lately it seems as though studios are giving players more to do to fill in the gap of the long wait and take the edge off the impatience: Guild Wars: Hall of Monuments Star Wars: The Old Republic: Guild registration and structuring Dragon Age: The Journeys flash game The Secret World: ARG and faction test Heck, even giving us special promotions to hunt down in the real world (like Del Taco's STO shuttle offer) is usually preferable to sitting on one's butt. It's a satisfying feeling to not only be given a task to do, but to know that that task will ensure you a nice little bonus, toy or trinket in the game when it launches. It's why the appeal of pre-orders (with their assured bonuses) is so strong. I know dev teams are pretty much absorbed 100% with testing, polishing, and creating new systems for the game in the months leading up to launch, but if the studio can swing it, special promotions, games and tasks can not only appease anxious players but grab some extra publicity in doing so. After all, there's never going to be a time post-launch where the studio has the playerbase's attention so fully as it does prior, so why not take advantage of that?
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Legendary South African photojournalist, Peter Magubane, has documented some of the country's most significant events. From the women's march to Pretoria in 1956 and the tragic events that unfolded in Sharpeville in 1960 to the release of Nelson Mandela from Robben Island in 1990. His images exposed the world to the injustices of the apartheid regime as well as the incredibly resilient spirit of those who fought for freedom. His impressive body of work, most notably the coverage of the June 16 student uprisings in 1976, earned him worldwide acclaim and made him an icon of the anti-apartheid movement. Today, June 14, Massmart together with Seriti sa Sechaba Publishers NPC, are proud to launch Peter Magubane's latest offering. Titled June 16, the book offers a deeper look and what he hopes is a greater understanding of the 1976 Soweto student uprising. "At the heart of Massmart's social sustainability approach is a desire to support social equality initiatives in our business, supply chain and the communities we serve. We hope to achieve this objective by nurturing talent and creating opportunities. When we were made aware of this project and Seriti sa Sechaba Publishers's work, we knew we had to be involved," says Massmart Chairman Kuseni Dlamini. "This book is an important record of both our pain and triumph. It also demonstrates the genius of Peter Magubane. Seriti sa Sechaba is very grateful for the support of Massmart who, right from the start, recognised the importance of what we were trying to do and gave not only financial but also moral support and encouragement" says Christine Qunta, publisher at Seriti sa Sechaba Publishers NPC, a non-profit organisation that helps established and first time black writers to publish and promote their books. Written by renowned journalist Joe Latakgomo and including a foreword by Winnie Madikizela Mandela, Magubane's book offers more than visual accounts of the Soweto student uprising. It is a brilliant chronicle of what happened before and after one of the most significant events in South Africa's history. Massmart is a managed portfolio of four divisions, each focused on high volume, low margin, low-cost distribution of mainly branded consumer goods for cash, through 414 stores in 13 countries in sub-Saharan Africa. Massmart's corporate social investments are wide ranging and include feeding schemes, literacy programmes to supporting the arts. We also try, wherever possible, to identify opportunities to leverage our retail capabilities to optimize the impact of our social upliftment activities.
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Erdogan says West ignores famine in Africa Turkiye, World, Africa President accuses developed countries of turning blind eye to famine facing 14 million people The West has ignored the plight of 14 million people facing famine in Africa, President Recep Tayyip Erdogan said Wednesday. Turkey would continue to stand alongside "suffering people trying to keep alive in poverty," he added at an Ankara press conference with Somalian President Mohamed Abdullahi Mohamed. "At least 14 million people, mostly women and children, are starving in Africa," he said. "Many developed western countries play the ostrich in the face of such human tragedies." Erdogan said Turkey had prepared aid for those countries in need of assistance. "Unlike those who turn a blind eye to those who are trying to keep alive in poverty and starvation, we will continue standing by them. You cannot talk about peace and stability in a world where children are starving to death." Erdogan said Somalia had seen a significant period of change since he first visited the country in 2011, highlighting February's presidential election as an example. Mohamed praised Turkey's reconstruction efforts in the Horn of Africa state. "Turkey has made important contributions to the reconstruction of Somalia after a very long working period," he said. "Somalia will continue seeking support from this relation." He added that the "fruitful" meeting with Erdogan had confirmed deep-rooted ties between the nations. "At the moment, we have had many agreements in different fields, such as cooperation on development and cultural exchange," he told journalists. "The business alliance between the two countries is progressing very quickly. In particular, the relationship between trade and business circles is very intense." Nearly 900,000 people in Somalia are currently "in crisis and emergency conditions" while almost 2 million Somalis suffer from food insecurity, according to the UN. Another 1 million are refugees in neighboring countries. In January, the World Food Program said around 14 million people in southern Africa were facing hunger due to drought. *Reporting by Enes Kaplan and Ozcan Yildirim; Writing by Sibel Ugurlu famine Mohamed Abdullahi Mohamed Recep Tayyip Erdogan Somalia Turkiye reports nearly 72,000 COVID-19 cases UAE uses 'humanitarian diplomacy' to mend fences with Somalia Turkiye to send 700 tons of aid to Afghanistan on 'charity train' Russia welcomes any efforts contributing to Ukrainian settlement: Kremlin Swiss prosecutor's office launches case over banner targeting Turkish president Suicide bomb blast in Somali capital kills at least 4 Drought displaces nearly 250,000 in Somalia
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Question of Palestine home || Permalink || About UNISPAL || Search Follow UNISPAL RSS Twitter Source: World Bank World Bank Expresses Support for Palestine Investment Conference Ramallah, March 29, 2008- Dr. Hasan Abu Libdeh, director of the Palestine Investment Conference (PIC), which will convene in Bethlehem in May, met Tuesday with David Craig, World Bank West Bank & Gaza Country Director. Dr. Abu Libdeh briefed Mr. Craig on progress in organizing the conference and expected international and Arab participation, and discussed the World Bank's role in the conference. Mr. Craig stated that senior World Bank managers and technical experts were expected to participate in the conference, along with colleagues from its sister organizations in the World Bank Group, the International Finance Corporation (IFC) and Multilateral Investment Guarantee Association (MIGA). Mr. Craig said: "The World Bank believes that the private sector is the necessary engine to drive sustainable economic growth in the West Bank and Gaza. This is an important conference with potential to create momentum for change and attract foreign investment. World Bank analysis has shown the investment climate in the West Bank and Gaza to be less bureaucratic and more transparent than other countries in the region. If matched with the lifting of movement and access restrictions, the growth potential of the Palestinian economy would be substantial. Therefore, we hope this timely conference will provide potential investors with a first-hand view of the investment potential in the Palestinian Territories, and allow them to both mobilize and benefit from the opportunities here." For further information, please go to: www.worldbank.oprg/ps
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Nicely Appointed Bi-Level with Oversized 2 Car Garage! Perfect for Home & Yard for Entertaining! Fabulous, Updated & Well Maintained! New Roof! New Windows! New Flooring! Updated Since Purchase-Garage Doors, Fence, Deck, Paver Patio, Most Appliances, Fireplace, Blinds, Sliding Glass Door, Hot Water Heater, 220 Wiring & Much More! Quiet Street! Two Full Baths! LL Recently Remodeled! Superb Find!
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HomeSocietyLife in Biden's America: Watch Your Door! Life in Biden's America: Watch Your Door! The Editors - December 12, 2021 FBI raids on the homes of American housewives would not shock the Nazis of the 1930s. The rest of us need to realize they could be coming for us next. By Sheryl Kaufman Russian novelist Aleksandr Solzhenitsyn wrote of Stalin's 1940s Russia, "It has, after all, been explained to us that the heart of the matter is not personal guilt, but social danger. One can imprison an innocent person if he is socially hostile. And one can release a guilty man if he is socially friendly." Does this not ring familiar in America today? Compare the fates of the January 6 political prisoners to the 2020 summer rioters. Two very specific recent incidents have not received the media attention they deserve. In Mesa County, Colorado, middle America, two women's homes were raided by the FBI. Here's their story as told to me: On the morning of November 23, FBI agents invaded the homes of Gold Star mom Tina Peters and home school mother Sherronna Bishop. Armed agents dressed in SWAT gear spent five hours combing thru every inch of Tina Peters' belongings, including the previously untouched box of her Navy Seal son's personal effects and letters, including photos of his dead body. Across town, the FBI rammed the door at Sherronna Bishop's home as she was homeschooling her children, in her pajamas. They handcuffed Sherronna and her husband, forced them into the front yard not fully dressed, with children still in the home.In both cases, agents took every cell phone, computer and laptop, took pictures of every room, and treated Tina and Sherronna and their families with disregard and aggression. What was their crime? Neither woman knows, but here is some background. Tina was elected Mesa County, Colorado Elections Clerk in 2017. She worked closely with Dominion Voting Systems and was assured that the voting machines were secure and could not connect to outside entities. After the 2020 election, constituents and others approached Tina about problems with Dominion, but she was skeptical. It wasn't until after a careful examination of the data that Tina discovered blatant inconsistencies. When local authorities decided to eliminate 2020 data, Tina captured images of what they removed. Her actions were lawful. Election data in Colorado is to be kept for 24 months, and it is her job to secure that data. Subsequently, her office was raided and she was locked out and removed her from her duties. Following the raid on her home, she went out of state in concern for her safety, but the hotel room where she was staying was ransacked. Even though she remains Elections Clerk, she has no access. Her staff is being charged with crimes, some fired, and Tina is now being turned into a criminal both in public perception and reality. Authorities in Colorado have somehow managed to have her husband, who has dementia and is in a nursing home, serve her with divorce papers. Newspapers articles and media are painting her as a criminal with no character. She is heartbroken and frightened. She is 66-years old. Sherronna spearheaded the effort that led to the turnover of nine school boards in Colorado. The Superintendent of Schools turned her name and the names of others over to the Justice Department after Attorney General Merrick Garland's decree calling on to the FBI to mobilize against parents who speak out at school board meetings. Sherronna, an ally of Tina's, is involved in election integrity efforts and further, was campaign manager for Congresswoman Lauren Boebert. Both women are bold but frightened. The Republican Party in Colorado appears to be complicit with their isolation and persecution and all the authorities surrounding them have turned their wrath on both. What is happening here? Why have the U.S. Department of Justice and local authorities criminalized these two American citizens who appear to have been acting within their constitutional rights and responsibilities? The problem is not just at the top of intelligence agencies. Something has convinced agents on the ground that raiding homes of ordinary citizens is OK. Maybe it was President Joe Biden's comments that "white supremacists" are the greatest threat to our national security. Or perhaps Attorney General Merrick Garland's directive that people who speak at school board meetings should be treated as domestic terrorists. This is not normal in our constitutional republic. So why has this travesty not been a top story in the media? Even conservative talk show hosts and newspapers won't touch it. How many other FBI raids are being quietly swept under the rug? Two reasons are apparent, although both are appalling condemnations of our times. First, many media outlets are silenced by lawsuits or threats of suits for daring to question fraudulent votes in the 2020 elections. Secondly, there are simply so many other travesties competing for airtime and headlines. Think of that — the FBI is raiding American homes as though these ladies were violent terrorists and it's not worth airtime! That in itself is a significant condemnation of life in Biden's America. Harken the words of Solzhenitsyn, and watch your door. Sheryl Kaufman is a Member of the Board of Americans for Limited Government. The post Life in Biden's America: Watch Your Door! appeared first on Daily Torch. * This article was originally published at Daily Torch breaking news Politics Society
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NextIntegrative Medicine: "Patient-Centered Care" is the new Medical Paternalism Basic ScienceCancerLegal Dr. Stanislaw Burzynski, antineoplastons, and the selling of an orphan drug as a cancer cure David Gorski on December 12, 2011 Over the last couple of weeks, I've been spending a lot of time (and, characteristically, verbiage) analyzing the phenomenon known as Dr. Stanislaw Burzynski and his "cancer cure" known as antineoplastons. In part I of this series, Stanislaw Burzynski: Bad medicine, a bad movie, and bad P.R., I used the legal threats against bloggers criticizing the credulous promotion by the British press of fundraising campaigns to send children with terminal cancer to the Burzynski Clinic and the promotion of the medical propaganda movie Burzynski The Movie: Cancer Is Serious Business to review the movie's claims and look into Burzynski's claims for antineoplastons. Not surprisingly, I found the evidence for extravagant claims for their anticancer effects unconvincing. In part II, Dr. Stanislaw Burzynski's "personalized gene-targeted cancer therapy": Can he do what he claims for cancer?, I looked into Dr. Burzynski's recent efforts to "diversify his portfolio, in which he has apparently decided to ride the new wave of genomic medicine to claim he can do "personalized, gene-targeted cancer therapy." I concluded that he does appear to do that, only very badly, in essence "making it up as he goes along." In this third and final part, I want to come back to antineoplastons, because it has been pointed out to me that there is an aspect of this story that has received little attention. One reader in particular has helped enormously in my education about this aspect of the Burzynski saga. I wish I could credit this person by name, but, for reasons I fully understand, I can't. However, this person's input was essential, and I've even appropriated (with permission, of course) a little bit of text here and there from our e-mail exchanges to "integrate" into this post. Putting this together with information in my previous posts, I think we can come to some conclusions about what it is that Dr. Burzynski is really doing. Burzynski and an orphan drug In the first part of this series, I pointed out that back in the 1970s Dr. Burzynski claimed to have discovered cancer-fighting substances in human urine, which he dubbed "antineoplastons," claiming that patients with cancer had lower levels of these substances in their blood and urine. However, I was pretty vague about just what these substances were, other than to point out that they were modified amino acids and that since 1980 Dr. Burzynski has been synthesizing them in a chemistry lab rather than isolating them from urine as he had done up until then. This vagueness came simply from my interest in moving straight to looking at Burzynski's claims rather than what these substances were. In retrospect, that might have been a mistake. The reason is that understanding what two of Burzynski's antineoplastons are is critical to understanding what he is doing with them and why he might occasionally appear to be observing an antitumor response. If you wander over to the Burzynski Clinic website, you'll note that he's kind enough to have provided the actual chemical structures of what he calls the active ingredient of antineoplastons. These include phenylacetate sodium (PN), phenylacetylglutaminate sodium (PG), phenylisoacetylglutaminate sodium (isoPG), and 3-phenylacetyl-2, 6-piperidinodione (A10). According to Quackwatch: By 1985, Burzynski said he was using eight antineoplastons to treat cancer patients. The first five, which were fractions from human urine, he called A-1 through A-5. From A-2 he made A-10, which was insoluble 3-N-phenylacetylamino piperidine 2,6-dione. He said A-10 was the anticancer peptide common to all his urine fractions. He then treated A-10 with alkali, which yielded a soluble product he named AS-2.5. Further treatment of AS-2.5 with alkali yielded a product he called AS-2.1. Burzynski is currently treating patients with what he calls "AS-2.1" and "A-10." In reality, AS-2.1 is phenylacetic acid (PA), a potentially toxic substance produced during normal metabolism. PA is detoxified in the liver to phenylacetyl glutamine (PAG), which is excreted in the urine. When urine is heated after adding acid, the PAG loses water and becomes 3-N-phenylacetylamino piperidine 2,6-dione (PAPD), which is insoluble. Normally there is no PAPD in human urine. What Burzynski calls "A-10" is really PAPD treated with alkali to make it soluble. But doing this does not create a soluble form of A-10. It simply reinserts water into the molecule and regenerates the PAG (Burzynski's AS-2.5). Further treatment of this with alkali breaks it down into a mixture of PA and PAG. Thus Burzynski's "AS-2.1" is nothing but a mixture of the naturally occurring substances PA and PAG. If you peruse ClinicalTrials.gov for Burzynski's current clinical trials, you'll find that pretty much all of them use antineoplastons AS-2.1 and A-10; i.e., phenylacetic acid (PA) and phenyl acetyl glutamine (PAG). But wait! you might say. Why does this matter? PA and PAG are not sodium phenylbutyrate! True enough. However, right there, in one of the e-mails from Renée Trimble, PR flack from the Burzynski Clinic. I had asked her in an e-mail how the Burzynski Clinic did its "personalized gene-targeted cancer therapy," and she responded: The combination contains drugs which have synergistic activity which permits reduction of doses. The combination proven ineffective by prior data, is not used. Antineoplastons and their prodrug, phenyl butyrate, are important ingredients of the combination because they cover the spectrum of approximately 100 genes. Two articles in peer reviewed journals have been published by our group recently and are attached. I've discussed the fallacy of the "100 to 200 genes" before in parts I and II of this series. However, what caught my eye was the statement that phenylbutyrate is a prodrug for these antineoplastons. For those who are not familiar with basic pharmacology, a prodrug is a drug that is metabolized into something else, and that "something else" produces a a therapeutic effect, either by itself or in combination with unaltered drug and/or other metabolites. In other words, a prodrug undergoes a chemical conversion in the body into something active. Often, the prodrug has no activity, and all of its pharmacological activity is due to the metabolite. It is also interesting to note that the complaint against Dr. Burzynski from the Texas Medical Board also mentions phenylbutyrate: Respondent prescribed a combination of five immunotherapy agents – phenylbutyrate, erlotinib, dasatinib, vorinostat, and sorafenib-which are not approved by the Food and Drug Administration ("FDA") for the treatment of breast cancer, and which do not meet the FDA's regulations for the use of off-label drugs in breast cancer therapy. One of the papers that Ms. Trimble sent to me also features sodium phenylbutyrate. It's a paper testing phenylbutyrate on esthesioneuroblastoma and nonsmall cell lung cancer and explains its rationale thusly: Sodium phenylbutyrate (PB) is an FDA-approved drug for urea cycle disorders, and it is also indicated for the treatment of primary and recurrent glioma and acute promyelocytic leukemia [5,6]. PB is partially metabolized in the human body into phenylacetate (PN) [7]. Both PB and PN have been extensively studied for their effect on neuroblastoma [8]. Integration of PB into ne- uroblastoma therapy has been highly recommended [9]. Previous studies reveal that PB has cytotoxic effect on human neuroblastoma, and that it can be combined with cisplatin in novel chemotherapy regimens [8]. PB is a histone deacetylase (HDAC) inhibitor. New publications recommend the use of such FDA-approved drugs for the treatment of neuroblastoma [10,11]. And there you have it. What Burzynski calls antineoplastons are nothing more than the byproducts of the body's metabolism of the orphan drug sodium phenylbutyrate. In fact, according to the paper cited, the "conversion of phenylbutyrate to phenylacetate was extensive (80 ± 12.6%), but serum concentrations of phenylacetate were low owing to rapid, subsequent conversion to phenylacetylglutamine." In other words, phenylbutyrate is nearly completely converted to PA, which is then rapidly converted to PAG. According to this study, within about four hours of an IV dose, phenylbutyrate levels in the blood approach zero, even in a patient receiving 2,000 mg/m2. This sort of conversion of a prodrug to a drug is not at all uncommon. For example, one common chemotherapy drug used in breast cancer and a lot of other malignancies, cyclophosphamide, works through its metabolite 4-hydroxycyclophosphamide, or 4-HC. As for phenylbutyrate being a "targeted" therapy, yes, it does target genes, but not in the way commonly meant when we refer to "targeted therapy," which normally refers to targeting either one gene product or a handful of related gene products (i.e., similar tyrosine kinases). Instead, phenylbutyrate targets lots of genes, making it in essence no more "specific" than many kinds of chemotherapy. Let's explore the implications of this little-publicized bit of information about antineoplastons. It's something that Dr. Burzynski doesn't exactly go out of his way to publicize. The orphan drug that works wonders Sodium phenylbutyrate, it turns out, is a drug that was originally marketed as a treatment for urea cycle disorders. It goes under the trade names Buphenyl (Ucyclyd Pharma, Hunt Valley, USA Ammonaps (Swedish Orphan International). As you might gather from the name of the Swedish company that makes it, it is an orphan drug. What that means is that it is a drug that was developed to treat a rare medical condition. Because so few people suffer from such conditions (they are, after all, rare), there is little profit to be made in selling such drugs, meaning that for a pharmaceutical company it doesn't make economic sense to go through the many hundreds of millions of dollars that it requires to obtain FDA approval for such drugs for such indications. That doesn't even take into account that it might be difficult to accrue enough patients to do a phase III clinical trial to demonstrate efficacy and safety. Both the U.S. and the European Union have laws to facilitate the development and marketing of orphan drugs. It turns out that sodium phenylbutyrate potentially has several indications. There is, of course, the aforementioned treatment of urea cycle disorders, which are inborn errors of metabolism. However, that's not the only indication, as can be deduced by searching PubMed and ClinicalTrials.gov for the search term "phenylbutyrate." What you'll find are over 1,300 articles on PubMed and 35 clinical trials on ClinicalTrials.gov. These clinical trials include trials testing phenylbutyrate in amyotropic lateral sclerosis (i.e., Lou Gehrig's disease), spinal muscular atrophy type I, spinocerebellar ataxia type 3, and, of course urea cycle disorders. Doing a search for "phenylbutyrate AND cancer" on PubMed and ClinicalTrials.gov is also informative. There are currently several trials listed on ClinicalTrials.gov, most of them completed. Trials of sodium phenylbutyrate that do not list Dr. Burzynski as an investigator including trials of lung cancer, prostate cancer, metastatic solid tumors unresponsive to chemotherapy. Most of these trials are either completed or terminated, and some of them even have published results. For example, here are the results from a phase I clinical trial in glioma, conducted by the New Approaches to Brain Tumor Therapy (NABTT) CNS Consortium, which is funded by the National Cancer Institute (NCI), and published in Neuro-Oncology in 2005. Sadly, they are not promising, even for a phase I trial, which, as you might recall, is the preliminary "first in humans" sort of trial designed to test for safety and maximum tolerated dose, not efficacy, except as a secondary endpoint: Of the 23 patients enrolled, 19 could be evaluated for tumor response. One CR and no PRs were noted, providing an overall response rate of 5% (95% confidence interval, 0–26%). Five patients (four GBM, one AA) demonstrated stable disease (SD) as the best response and a median time to progression of 5.4 months (range, 1.9–5.7 months). Thirteen patients (11 GBM, 2 AA) demonstrated progressive disease without a period of SD, and they all received fewer than four cycles of PB therapy. Fifteen patients were on enzyme-inducing anti-epileptic drugs. Of note, four of the six patients with CR or SD were on enzyme-inducing antiepileptic drugs. Nineteen of the 20 patients who could be evaluated for survival have died. The total number of person-years of follow-up was 18.2, and the surviving patient has been followed for more than five years. Median survival time was 5.4 months. There are other trials as well, a few of which I will briefly mention: The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo. (Preclinical study.) This study used a modified version of sodium phenylbutyrate (AR-42, also known as OSU-HDAC42) in preclinical models of B-cell malignancies including cell culture and SCID mice to show that AR-42 showed promise in this class of malignancies. A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.. (Phase I trial.) Conclusion: ""The combination of 5-AC and phenylbutyrate across three dose schedules was generally well tolerated and safe, yet lacked any real evidence for clinical benefit." Combination of cytotoxic-differentiation therapy with 5-fluorouracil and phenylbutyrate in patients with advanced colorectal cancer. (Phase I trial) Conclusion: "Weekly infusions of FUra followed by PB were fairly well tolerated with disease stabilization in 3/4 (75%) of patients. This is the first report to demonstrate the feasibility of combining a cytotoxic agent with a HDACi as a cancer treatment." Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors. (Phase I trial.) Conclusion: "Administration of PBA in a twice-daily infusion schedule is safe. The maximum tolerated dose is 300 mg/kg/day. Study designs with more convenient treatment schedules and specific molecular correlates may help to further delineate the mechanism of action of this compound. Future studies evaluating PBA's ability to induce histone acetylation and cell differentiation alone or in combination with other anti-neoplastics are recommended." Complete response of a recurrent, multicentric malignant glioma in a patient treated with phenylbutyrate. (Case report.) After treatment of an anaplastic astrocytoma of the frontal lobe with radiation therapy and Procarbazine-CCNU-Vincristine, the tumor recurred as multiple lesions in this patient, who was started on sodium phenylbutyrate. This patient's tumors regressed over nine months until they disappeared. Her complete response lasted over 20 months, which continued after discontinuation of sodium phenylbutyrate. The authors concluded: "This is the first report, to our knowledge, of a complete and durable response of a malignant glioma to phenylbutyrate. These clinical findings are consistent with the antiglioma effects of phenylbutyrate noted by Engelhard et al. [4], who described antiproliferative effects, inhibition of urokinase and c-myc expression, as well as impairment of cell migration and invasiveness, and induction of differentiation." If you look over the PubMed references, it turns out that researchers first examined phenylacetate as a potential treatment for cancer as far back as 1959, and there are some clinical trials still listed on ClinicalTrials.gov testing phenylacetate against various cancers, although there is understandably some overlap with the trials testing sodium phenylbutyrate, most likely because somewhere in the trial it's mentioned that phenylacetate is a metabolite of phenylbutyrate. This trial, however, only used phenylacetate in children with recurrent or progressive brain tumors. It's been completed, but unfortunately no results have yet been reported. But why should sodium phenylbutyrate be suspected to be a potential anticancer drug? It turns out that it inhibits an enzyme known as histone deacetylase. Histones, the molecular biology geeks out there will know, are proteins around which DNA is wrapped in such a way that a "scaffolding" is formed. The whole complex of DNA and its associated proteins is called chromatin. When DNA is wrapped around its histones, it is usually transcriptionally inactive or silent; i.e., it's not transcribed into RNA and translated into protein. Histone acetylases and deacetylases modify histones to make them either more or less "sticky," respectively, to DNA. In other words, chromatin that is more acetylated is generally more active in making its gene products and chromatin that is less acetylated is less active or even silent. Indeed, histone acetylation and deacetylation are major epigenetic mechanisms of controlling gene activity. It turns out that histone deacetylase (HDAC) inhibitors (HDIs) can have anticancer effects by inducing the accumulation of hyperacetylated chromatin, thus shutting down certain genes, and inhibiting the acetylation of other proteins that regulate gene expression. Some of the mechanisms proposed include inhibition of a protein known as p21WAF1/CIP1, which regulates p53, among others. No doubt this is the sort of rationale that leads Dr. Burzynski to tout his claim that his antineoplastons shut down "100 to 200 genes." Currently, besides sodium phenylbutyrate, two other HDAC inhibitors are FDA-approved: Vorinostat and Romidepsin, both for cutaneous T-cell lymphoma. Several others are in the pipeline, from phase I to phase III clinical trials. Of interest, note that Dr. Burzynski combined Vorinostat with phenylbutyrate (and several other drugs) in one of the patients in the Texas Medical Board complaint. Why he would combine two HDAC inhibitors, I don't know. Normally in cancer therapy, we try to target different mechanisms when combining drugs. One interesting take on phenylbutyrate as a cancer treatment can be found at, of all places, the website of an insurance company. Basically, Aetna has a policy regarding antineoplastons and phenylbutyrate which is worth considering. Aetna states that it considers antineoplastons and associated medical services to be "experimental and investigational because there is insufficient evidence published in the peer-reviewed medical literature validating the effectiveness of antineoplaston therapy for any indication." However, in contrast, Aetna considers sodium phenylbutyrate to be: "…medically necessary for the treatment of acute promyelocytic leukemia and malignant glioma." "…experimental and investigational for the treatment of breast cancer, prostate cancer or cancers other than acute promyelocytic leukemia and malignant glioma." "…experimental and investigational for the treatment of amyotrophic lateral sclerosis, beta-thalassemia, insulin resistance and beta-cell dysfunction, maple syrup urine disease, sickle cell anemia, spinal muscular atrophy, and for all other indications." Insurance companies tend to be pretty conservative in deciding what therapies to cover; so the fact that Aetna will cover sodium phenylbutyrate for some indications, including at least one cancer, puts a rather fascinating spin on the issue that will become important later in this discussion. A blind squirrel At this point, the reader might be tempted to ask whether ol' Dr. Gorski has gone off the deep end and become a Burzynski apologist. He might be wondering whether I'm invoking a couple of old and corny sayings about how even a blind squirrel finds an acorn every once in a while or how a stopped clock is correct twice a day. Such a reader has only to go back to part II in my series to disabuse himself of that notion, given how I pointed out that it's not the concept of "personalized gene-targeted therapy" to which I object. It's how Burzynski does it and how he corrupts the very concept through his "everything but the kitchen sink" approach to throwing "targeted" therapies at cancer patients willy-nilly without a systematic rationale for picking them or, it seems, any concern for potential adverse reactions due to combining drugs that have not been tested adequately in combination. My point is that the Burzynski saga is more complicated than the simple narrative that a lot of skeptics, even skeptics I admire greatly, have imposed on it, which appears to be that Burzynski is a quack; antineoplastons are "toxic byproducts" and don't work; and that's that. Even I fell into that way of thinking for a long time. However, whether or not I think Dr. Burzynski is a quack is a question I'll leave for the very end of this post. In the meantime, let's put sodium phenylbutyrate and antineoplastons in context. While it is true that, thus far, there is little evidence that sodium phenylbutyrate is effective in most cancers (some brain tumors like gliomas might be an exception), it's also not correct from a scientific and skeptical standpoint to dismiss it, and thus antineoplastons, out of hand. There is enough evidence out there (the complete response in a glioma patient, for instance) to suggest that there might—just might—be something to this approach. However, is it a magic bullet? Of course not! And that's where Dr. Burzynski goes astray. Not only is he "doing it wrong" but he's "selling it wrong" as well, charging huge sums of money for his special cocktail of targeted therapies and sodium phenylbutyrate under the guise of clinical trials and forcing patients to bear the cost, while enticing them to bear that cost by making extravagant promises and wrapping his selling of antineoplastons up as part of "personalized gene-targeted therapy." He's also prescribing huge doses of antineoplastons (up to 25 g/kg/d for A10 and 80 mg/kg/d for AS-2.1, as we have seen). both of these are so far above the maximal tolerated dose of 300 mg/kg/d determined in the phase I trial I cited above as to be terrifying. True, in all fairness, antineoplastons A-10 and AS-2.1 are not sodium phenylbutyrate, making comparisons of MTDs perilous, but they are metabolites of this drug and their molecular weights are not so different that using nearly 100-fold more than the MTD seems advisable or safe. It's also true that Dr. Burzynski often claims that very high doses are needed to be effective. Indeed, a key part of the collapse of his NCI trial in the 1990s was due to Dr. Burzynski's unhappiness with the dosing schedule and his belief that it should be higher, while the NCI was concerned about the risk of serious side effects. Even if he were correct, which he might have been, a drug that requires doses so high that it causes hypernatremia due to the sodium in its salt is rarely a particularly useful drug. Even worse, switching to phenylbutyrate as drug that "generates neoplastons in the blood," as Burzynski has called it, isn't a particularly good strategy. The phase I trial I mentioned above that studied the pharmacokinetics of phenylbutyrate indicates that it's not a good source of phenylacetate, as the authors concluded: In summary, phenylbutyrate exhibits saturable, nonlinear pharmacokinetics after intravenous administration and achieves peak concentrations in the range of in vitro tumor activity. Concentrations of the active, intermediate metabolite (phenylacetate) were low in this study and did not achieve levels at which saturation occurs. The conversion of phenylbutyrate to phenylacetate was high (80%), but the rapid, subsequent conversation to phenylacetylglutamine resulted in serum levels of phenylacetate that were much lower than those seen when the drug is given intravenously. We conclude that phenylbutyrate should not be considered a clinically useful prodrug of phenylacetate and that phenylbutyrate and phenylacetate should be pursued as independent antineoplastic agents. In other words, Dr. Burzynski's rationale for using phenylbutyrate, namely that it's a prodrug for antineoplastons, while technically true, is deceptive in that pharmacokinetic studies indicate that phenylbutyrate does not generate clinically useful concentrations of PA in the blood. The PA is immediately metabolized to PAG, which is apparently not active. Also, as we have seen, the NCI's concerns were not without foundation, particularly its concern about the risk of severe hypernatremia, which several of Dr. Burzynski's patients have experienced. Also in all fairness, in the publications of two trials of sodium phenylbutyrate that Ms. Trimble sent me, Dr. Burzynski used 200 mg/kg/d or 6 g/d, which in a typical 70 kg adult is around 85 mg/kg/d, both of which are below the maximum tolerated dose determined in the study I mentioned above. Also, given that they are below the MTD, they are also almost certainly at a dose that fails to generate significant concentrations of "antineoplastons" in the blood. Worse, Dr. Burzynski is also adding sodium phenylbutyrate to a whole bunch of other drugs whose interactions with it have not been studied. As much as I hate to admit it, there is a modicum of science here. It's just that, in Dr. Burzysnki's hands, unfortunately it's incredibly sloppy science, and he extravagantly overpromises, while making a claim that is probably not true, namely that phenylbutyrate is a good source of antineoplastons. Trials are not designed so that they can ever answer the question of whether the real drug, namely sodium phenylbutyrate, is effective, either alone in combination, against cancer, and, if it is, against which cancers. Rather, they appear custom-designed so that Dr. Burzynski can keep administering antineoplastons (which, remember, are nothing more than the metabolic breakdown products of sodium phenylbutyrate) to patients. It's also incredibly unethical science in that Dr. Burzynski is requiring patients to pay huge amounts of money out-of-pocket for unvalidated combinations of targeted therapies thrown together with (these days, at least) sodium phenylbutyrate and sold as "personalized gene-targeted cancer therapy." As for his clinical trials, he has been warned by the FDA about lax Institutional Review Board procedures that fail to protect human subjects, fail to guarantee adequate informed consent, do not adequately monitor studies with ongoing reviews, and fail to report conflicts of interest of IRB members. In other words, not only does Dr. Burzynski do "personalized targeted therapy" badly; he does clinical trials badly as well. So what exactly is Burzynski up to? Why, if sodium phenylbutyrate is available from not one, but two pharmaceutical companies as an orphan drug and the NCI and many other researchers are investigating it (and were investigating phenylacetate before that), would Dr. Burzynski have such an interest in portraying himself as a "brave maverick doctor"? Why does he still have such an intense interest in attracting people to his clinic using the "antineoplaston" brand name, now coupled with his new brand, "personalized gene-targeted cancer therapy"? Why does he sell so much chemotherapy—yes, chemotherapy, as I have shown—along with cocktails of expensive targeted therapies which, although less toxic than cytotoxic chemotherapy, still carry risks, not to mention cost a lot of money? Why are Dr. Burzynski and his promoters so keen to portray his therapy is "nontoxic" and, above all, "not chemotherapy," even to the point of implying that it is a natural product rather than the product of big pharma, even though we have just seen that most of the drugs he uses are, in fact made by the big, bad pharmaceutical companies? Looking at the claims of the Texas Medical Board against Dr. Burzynski, which include overprescribing without benefit and running his own pharmacy, and the costs of treatment at the Burzynski Clinic, which are freely discussed on patient blogs such as Supatra's Fairy Fund and Cancer is a Bad ASS Bitch But We Are Badder (not to mention the claims of Wayne Merritt that Dr. Burzysnski is massively overcharging) that I discussed last week, I start to get the impression that what we are dealing with is not a misunderstood scientist or a "brave maverick doctor, but something more slippery, someone who skirts the fuzzy line between bad science and outright quackery for profit. This starts to become very important when you consider what price people will pay for hope. As far as I can see and based on what I've found out, Dr. Burzynski's antineoplastons appear to be nothing more than a different way of administering sodium phenylbutyrate. The difference is that they are administered at very high doses, and added to (in what appears to be most patients at the Burzynski Clinic these days) a luxury cocktail of chemotherapy and eye-wateringly expensive targeted cancer therapies prescribed off-label using a "Targeted Cancer Therapy for Dummies"-level interpretation of a genomic assessment of the patient's tumor the company Caris, which is still also at an experimental stage. Here's where it gets even more interesting. As I mentioned above, the insurance company Aetna has a policy outlining under what conditions and for what diseases it will cover sodium phenylbutyrate therapy. In that policy, it also states: Since sodium phenylbutyrate has been approved by the FDA for treatment of other indications, physicians can prescribe it for patients without any danger of legal sanctions or need for compassionate use exemptions. However, there is no adequate evidence in the peer-reviewed published medical literature demonstrating that the use of sodium phenylbutyrate improves the clinical outcomes of patients with cancers of the prostate, breast, or cancers other than acute promyelocytic leukemia and malignant glioma. Current evidence is limited to in vitro and in vivo studies and Phase I studies. Prospective Phase III clinical outcome studies are necessary to determine the clinical effectiveness of sodium phenylbutyrate for cancer. Note this phrase: "…physicians can prescribe it for patients without any danger of legal sanctions or need for compassionate use exemptions." Music to Dr. Burzynski's ears, no doubt, except that off-label use doesn't mean you can use a drug for whatever you want, particularly when, as the Memorial Sloan Kettering Cancer Center points out, each 500 mg tablet of sodium phenylbutyrate contains approximately 62 mg sodium. That's why at the doses Burzynski must be using, even the lower ones that he uses, there is considerable risk of side effects including hypernatraemia and death. So the main thing that Burzynski stands to gain from continuing the way he is continuing is uninformed patients who have (or, like some patients who manage to raise a lot of money through medical fund raisers, can get) lots of money. These are patients who are already prone to be attracted to woo and who have come to think from reading various websites and other sources of information that antineoplastons are somehow something magical and amazing. Of course, they don't realize it's nothing more than phenylbutyrate and, more importantly, that, if they have one of the cancers for which there is evidence of efficacy, they could ask their oncologist to prescribe the drug off-label, although their insurance may not pay for it and their doctor might not consider it advisable. Of course, I'd sooner rely on the judgment of almost any oncologist over that of Dr. Burzynski, given that Dr. Burzynski appears to want to give antineoplastons to every cancer patient. They also don't appear to be informed that there is a significant body of published evidence about the safety and efficacy of phenylbutyrate and that the way Dr. Burzynski uses its metabolites A-10 and AS-2.1 often far exceeds what one might estimate to be the MTD based on studies of their prodrug. What Burzynski is really doing It appears that during his urine and blood purification process so many decades ago, Burzynski stumbled on known compounds, PA and PAG, and has been using them to treat all sorts of cancers at extremely high doses based on weak evidence of clinical efficacy (probably brain tumours are the only real indication where it might be useful). Despite the persistent lack of evidence that these compounds have significant anticancer activity in humans, he continues to use and promote them at his clinic, charging patients through the nose to join his clinical trials rather than joining in a wider research effort test the drug in the right way. Indeed, the Burzynski website is still putting out this line: "Antineoplastons (ANP) are peptides and amino acid derivatives, discovered by Dr. S. Burzynski, M.D., Ph.D. in 1967." As the literature shows, however, what is probably one active metabolite (phenylacetate) was already being researched in the 1950s, and the other probable active metabolite, phenylacetylglutamine, was investigated in the urine of cancer patients in 1958. Burzynski didn't "discover" these two chemicals. All he did was to purify them from urine, then throw them them at patients in extremely high doses. This he did for decades until, sometime in the last several years, he apparently discovered that these chemicals are metabolites of sodium phenylbutyrate; so he switched to that. Then, like the "brave maverick doctor" that he thinks himself to be, he decided that the way to sell his antineoplastons and phenylbutyrate was to "rebrand" them as part of his "personalized gene-targeted cancer therapy." So, after all this, including my previous two posts on Dr. Burzynski's therapies, what can we conclude? At least three things: Although this probably wasn't true 10 or 20 years ago (mainly because it wasn't so widely known that PA and PAG are metabolites of sodium phenylbutyrate), these days "antineoplastons" are just another name for phenylbutyrate, an orphan drug that any physician can prescribe off-label. Dr. Burzynski markets antineoplastons in the alt-med underground through movies like Burzynski The Movie and interviews with Suzanne Somers as "not chemotherapy," even though phenylbutyrate is an HDAC inhibitor, which is a class of chemotherapy drug under active research by many university laboratories and pharmaceutical companies. Either through gross incompetence or deception (take your pick), he is, in my opinion, misleading patients when he claims that phenylbutyrate is a good source of antineoplastons; it's not. Dr. Burzynski uses chemotherapy, and lots of it, in combinations that have not yet been demonstrated to benefit cancer patients, all based on reports from Caris. This he brands "personalized, gene-targeted therapy," even though, as I've said before, it's very much at the level of "Targeted Therapy for Dummies," in which he combines a bastardized version of metronomic chemotherapy with expensive cocktails of targeted agents. There is no evidence that his results are any better than those obtained elsewhere, despite his claims otherwise. Allegedly (according to Wayne and Lisa Merritt and the Texas Medical Board), Dr. Burzynski provides these drugs at inflated prices from his own pharmacy and without fully informing his patients about the treatment they're getting. The determination by the Texas Medical Board of whether this allegation is true or not awaits the results of legal proceedings against Dr. Burzynski that are scheduled to begin early next year. What cancer patients considering going to the Burzynski Clinic need to know is that antineoplastons (or to give them their correct name, phenylbutyrate) appear to be no better than many experimental therapies at a very early stage of development. There is phase I data that has produced toxicity data and an MTD. However, there is no convincing evidence of efficacy, except maybe in certain brain tumors. Indeed, it is quite possible, based on the case report and phase I trial testing phenylbutyrate in patients with glioma, that Dr. Burzynski's therapy does, almost quite by accident, produce the occasional complete response. The problem is that we have no idea if this is any better or worse than anyone else's results because Dr. Burzynski doesn't do the necessary phase III trials to find out, even though he has well over 60 phase I/II trials listed at PubMed over the last 15 or 20 years. Be that as it may, Dr. Burzynski's antineoplastons are not "natural, non-toxic compounds that cure cancer." They are drugs, plain and simple. Worse, they are drugs of unknown efficacy. Nor is Dr. Burzynski doing anything unique or in any way superior to what cancer researchers elsewhere do, his claims otherwise notwithstanding. In fact, what Dr. Burzynski does and how he does it are a pale shadow, a parody, of what real cancer research centers do. He does "personalized therapy" so badly that it's a joke, and he uses an orphan drug off-label in combination with other off-label chemotherapy drugs and targeted therapy while selling his combination as some sort of radical breakthrough in cancer therapy. Meanwhile, the alt-med underground promotes Dr. Burzynski as "the man who cures the most intractable cancers" naturally. He's not. He's being represented to desperate patients with incurable cancers as their "last hope," worth any price to reach. After all, what price would you pay for your last chance at survival or that of a loved one? Of your child? To what lengths would you go to get to the man who, you are told, is the only man in the world who can save your life? Unfortunately, it's not even clear to me that Dr. Burzynski's cured a single cancer. In fact, Skeptical Humanities has been tallying publicly available cases of patients who went to Burzynski and did not survive. It's a depressing read, and these are stories we don't see, even from much of the mainstream press. In the process, the harm he is doing is incalculable as he tarnishes the reputation of a perfectly fine experimental anticancer drug (phenylbutyrate) and the very concept of "personalized cancer therapy" with the stench of quackery. Certainly, it doesn't help that of late he's branched out into dubious anti-aging remedies, forming a new division of his clinic called AminoCare. One of his products is even called AminoCare A10, which is billed as being made of "blend of amino acids, an amino acid derivative and vitamin B2." (Any guess as to what Dr. Burzynski's "proprietary" amino acid derivative is, given the name A10?) Which brings me back to the question of whether Dr. Burzynski is a quack. My answer may surprise you: Although he might be one, in the end I don't really care that much if he is or not. Certainly (and not surprisingly), Dr. Burzynski is emphatic that he is not. However, to me the line between being a quack or "merely" a bad doctor and scientist is a blurry one. Quack Dr. Burzynski might be, but to me more important than whether or not he is a quack is how he behaves. Even if the science Burzynski were doing were pristine, how he is selling himself and his products to his patients as the one man who has what can cure cancer speaks volumes about his ethics, and what's in those volumes is not good. The Burzynski Clinic's motto might be, "First, do no harm." However, Dr. Burzynski's actions, coupled with the lack of evidence supporting his methods, make that slogan ring hollow these days. One can only hope that the Texas Medical Board finally puts a stop to his activities. The complete Burzynski series: Stanislaw Burzynski: Bad medicine, a bad movie, and bad P.R. Dr. Stanislaw Burzynski's "personalized gene-targeted cancer therapy": Can he do what he claims for cancer? Posted in: Basic Science, Cancer, Legal, Medical Ethics, Pharmaceuticals, Politics and Regulation Tagged in: Burzynski Clinic, Burzynski Research Institute, cancer, Caris Life Sciences, chemotherapy, Genomics, glioma, personalized gene-targeted cancer therapy, personalized therapy, Stanislaw Burzynski Posted by David Gorski Dr. Gorski's full information can be found here, along with information for patients. David H. Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute specializing in breast cancer surgery, where he also serves as the American College of Surgeons Committee on Cancer Liaison Physician as well as an Associate Professor of Surgery and member of the faculty of the Graduate Program in Cancer Biology at Wayne State University. If you are a potential patient and found this page through a Google search, please check out Dr. Gorski's biographical information, disclaimers regarding his writings, and notice to patients here. 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Q: Facebook OAuth creates new user each time using Passport and Express I am using the Passport node module in conjunction with Express to enable users to login via Facebook, Twitter, and Google. I have setup Facebook and Twitter so far and users can login successfully, but it creates a new user every time even though I have tried to make it recognize when a user has already created an account. Here is the code I am using: passport.use(new FacebookStrategy({ clientID: '********************', clientSecret: '***********************', callbackURL: "http://www.wundertutor.com:3000/auth/facebook/callback" }, function(accessToken, refreshToken, profile, done) { processProfile(profile, function(err, user) { if (err) throw err; done(null, user); }); })); function processProfile(profile, callback) { if (profile.emails) { profile.emails.forEach(function(email) { findUserByEmail(email.value, function(err, user) { if (user) { return callback(null, user); } }); }); var newUser = { id: profile.id, firstName: profile.name.givenName, lastName: profile.name.familyName, email: profile.emails[0].value }; user.create(newUser, profile.provider, function(err, user) { if (err) throw err; return callback(null, user); }); } } function findUserByID(id, callback) { pool.getConnection(function(err, connection) { var query = connection.query("SELECT * FROM users WHERE id = ?", id, function(err, rows) { connection.end(); var user; if (rows.length == 1) { user = { id: rows[0].id, role: rows[0].role, firstName: rows[0].firstName, lastName: rows[0].lastName, email: rows[0].email }; } return callback(null, user); }); }); } function findUserByEmail(email, callback) { if (email) { pool.getConnection(function(err, connection) { if (err) throw err; var query = connection.query('SELECT * FROM users WHERE email = ?', email, function(err, rows) { connection.end(); if (err) throw err; if (rows.length == 1) { console.log("C"); return callback(null, rows[0]); } else { return callback(null, null); } }); }); } else { return callback(null, null); } } passport.serializeUser(function(user, done) { done(null, user.id); }); passport.deserializeUser(function(id, done) { findUserByID(id, function(err, user) { done(null, user); }); }); In processProfile, I have it loop through each email associated with a user profile and check to see whether that user is already in our database. If they are, then it gets that user's info and passes it to the 'done' callback to be serialized and log the user in. The strange thing is that when a user who is already in our database is logged in, it does get to this part of the code and returns the user successfully (determined by a series of console.logs), but for some reason it still creates a new user in the database each time they try to log in. Also, on a side note, when I log in normally (via username and password), I am redirected to our learn page '/learn', but when I log in via Facebook, I am redirected to the learn page with some extra stuff afterwards '/learn#='. Any ideas? A: Try rewriting your processProfile function to something like this: function processProfile(profile, callback) { var result; if (profile.emails) { profile.emails.forEach(function(email) { findUserByEmail(email.value, function(err, user) { if (user) { result = user; } }); }); if( !user ) { var newUser = { id: profile.id, firstName: profile.name.givenName, lastName: profile.name.familyName, email: profile.emails[0].value }; user.create(newUser, profile.provider, function(err, user) { if (err) throw err; result = user; callback( null, result ); }); } else { callback( null, result ); } } }
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I just made myself a really big glass of Iced Tea and filled it with blueberries and basil and a just a touch of spearmint. Am I trying to push a recipe on my photo blog? Maybe. I just have a lot of basil. Maybe you do too? I'm telling you, put it in your lemonade, your iced tea, your water. You won't be disappointed. It's one billion degrees outside and inside or the pool seems like the only logical option- my youngest is making a ninja warrior course in my living room, and I'm trying best to remember all of the lovely moments of Janey and Dan's July 8th wedding day....with my delicious blueberry basil tea in hand . When I finished up Janey and Dan's Engagement session last summer in 2016, I just knew that their wedding day was going to be special. Janey and Dan are both just so lovely. I am thankful that I was able to spend lots of time during the engagement session getting to know them. We even were able to do some scouting out of places to take pictures on the wedding day. This was so very helpful- If you are a future bride or groom out there and you're reading this, make some time to do a little scouting before your wedding day for some good spots to take pictures. It's so helpful and makes for smooth transitions day of. There was a lot of attention to detail leading up to the wedding day...Janey and Dan were prepared and ready! I loved it! Janey and Dan's day was so pretty- The flowers were done by AN ENCHANTED FLORIST in Skippack Village. They were so gorgeous! Janey's Dress was Watters, from the Wedding Pavilion at Van Cleve in Paoli. Hair and makeup was done by the Citrus Salon and Day Spa at Blue Bell. I worked alongside Lucas and Alfredo of Rivre Films and they were just the nicest and coolest guys...cannot wait to see their film of the day! The Reception was held at the Historic William Penn Inn. And lastly but never least, thank you to Ralph, my amazing second shooter/best friend. Below are my favorite moments of the day, there were so many to choose from! I loved how casually Janey spent time with her friends before the wedding- I love how Janey could not stop twirling in her dress. I adored Dan's dinosaur cuff links, and his peacock bowtie. I love how Janey's mom was the maid of honor. I love how parents were involved in almost every moment of the day. I loved how when the clouds cleared that evening there was a giant full moon. Wedding days are busy and hectic for everyone involved- sometimes it's hard to breathe from one moment to the next. However, when that breath happens, when you stop and look around, surrounded by your family and your friends and oh so much love ; whether you're the couple getting married or in my case as someone photographing the wedding; the breath feels full and sweet, full of brilliant life and magic. It's in those moments that that I feel most thankful for this beautiful work that I'm choosing.
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Gilmore Mills is an unincorporated community in Rockbridge County, Virginia, United States. Gilmore Mills is located on the James River west-southwest of Glasgow. Annandale and the Varney's Falls Dam were listed on the National Register of Historic Places in 1993. References Unincorporated communities in Rockbridge County, Virginia Unincorporated communities in Virginia
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