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"es": "¿Por quién está escrito este documento?",
"fr": "Par qui ce document est-il écrit?",
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train_357 | null | {
"de": "Wie lautet das erwähnte Datum?",
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"es": "¿Cuál es la fecha mencionada?",
"fr": "Quelle est la date mentionnée?",
"it": "Qual è la data indicata?"
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"match_score": 1,
"matched_text": "January 21, 1999",
"start": 324,
"text": "January 21, 1999"
} | {"gt_parses": [{"question" : "What is the date mentioned?", "answer" : "January 21, 1999"}]} |
train_358 | null | {
"de": "An wen richtet sich dieses Dokument?",
"en": "To whom is this document addressed?",
"es": "¿A quién se dirige este documento?",
"fr": "À qui s'adresse ce document?",
"it": "A chi è indirizzato questo documento?"
} | [
"Mr. Larry Ellingson",
"Mr. Ellingson"
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"Source:",
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"start": 0,
"text": "DEPARTMENT OF HEALTH AND HUMAN SERVICES"
} | {"gt_parses": [{"question" : "to which department it belongs to ?", "answer" : "DEPARTMENT OF HEALTH AND HUMAN SERVICES"}, {"question" : "to which department it belongs to ?", "answer" : "department of health and human services."}]} |
train_360 | null | {
"de": "Von wem ist dieses Dokument geschrieben?",
"en": "By whom is this document written?",
"es": "¿Por quién está escrito este documento?",
"fr": "Par qui ce document est-il écrit?",
"it": "Da chi è scritto questo documento?"
} | [
"Kunio Iwatani"
] | [
"FROM",
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"DEMAS",
"FAX05-6204-2943",
"19994",
"18218",
"(*)",
"21",
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"Ltd.",
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"Dept.,",
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"Division",
"1-1",
"Doshomachi",
"4-chome,",
"Chuo-Ku,",
"Osaka",
"541,",
"JAPAN",
"Tel:",
"+81",
"6",
"(204)",
"2852",
"Fax:",
"+81",
"6",
"(204)",
"2943",
"TELEFAX",
"MESSAGE",
"To:",
"E.",
"Lilly",
"&",
"Company",
"Date:",
"January",
"21,",
"1999",
"Att:",
"Mr.",
"Larry",
"Ellingson",
"From:",
"Kunio",
"Iwatani",
"Executive",
"Director",
"Actos",
"Product",
"Team",
"CC:",
"Mr.",
"Hamanaka,",
"TPA",
"Subject:",
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"Matter",
"Dear",
"Mr.",
"Ellingson,",
"Enclosed",
"please",
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"a",
"copy",
"of",
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"letter",
"to",
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"FDA",
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"7,",
"1994.",
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"said",
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"preliminary",
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"in",
"the",
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"pioglitazone",
"did",
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"satisfy",
"Upjohn's",
"internal",
"requirement",
"for",
"reduction",
"blood",
"glucose;",
"therefore,",
"the",
"considerable",
"programs",
"required",
"for",
"development",
"of",
"pioglitazone",
"are",
"not",
"in",
"line",
"with",
"Upjohn's",
"business",
"needs.",
"-..",
"They",
"did",
"not",
"mention",
"about",
"safety",
"of",
"pioglitazone.",
"After",
"Upjohn's",
"decision,",
"Takeda",
"approached",
"FDA",
"and",
"consulted",
"whether",
"Takeda",
"might",
"go",
"further",
"the",
"clinical",
"development",
"works",
"on",
"pioglitazone.",
"Since",
"the",
"FDA's",
"response",
"was",
"positive",
"to",
"go",
"ahead,",
"Takeda",
"took",
"over",
"Upjohn's",
"works",
"and",
"finally",
"filed",
"NDA",
"on",
"January",
"15,",
"1999.",
"This",
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"the",
"story",
"of",
"the",
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"may",
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"the",
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"pioglitazone",
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"specially",
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"the",
"viewpoints",
"of",
"safety",
"issues,",
"it",
"might",
"be",
"advisable",
"for",
"us",
"to",
"keep",
"saying",
"that",
"Upjohn's",
"decision",
"is",
"based",
"on",
"JAN",
"21",
"'99",
"07:43",
"DALY",
"19",
"06",
"6204",
"2943",
"PAGE",
".",
"01",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"LLY-CRCARCH-00003000",
"Source:",
"https://www.indupbodsfoodonts.ucsf.edu/docs/nljf0226"
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"de": "Wie lautet das Datum der Einreichung?",
"en": "what is the date of submission?",
"es": "¿Cuál es la fecha de presentación?",
"fr": "Quelle est la date de soumission?",
"it": "qual è la data di presentazione?"
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train_362 | null | {
"de": "was ist die Telefonnummer (inklusive Vorwahl)?",
"en": "what is the telephone number (include area code)?",
"es": "¿Cuál es el número de teléfono (incluye el código de área)?",
"fr": "Quel est le numéro de téléphone (y compris l'indicatif régional)?",
"it": "qual è il numero di telefono (incluso il codice di zona)?"
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train_364 | null | {
"de": "was ist das Ablaufdatum?",
"en": "what is the expiration date ?",
"es": "¿Cuál es la fecha de caducidad?",
"fr": "Quelle est la date d'expiration?",
"it": "Qual è la data di scadenza?"
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"text": "November 30, 2002"
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train_365 | null | {
"de": "Wie lautet der Name des Sponsors?",
"en": "what is the name of the sponsor ?",
"es": "¿Cuál es el nombre del patrocinador?",
"fr": "Quel est le nom du sponsor?",
"it": "Qual è il nome dello sponsor?"
} | [
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"match_score": 1,
"matched_text": "Takeda Pharmaceuticals North America, Inc.",
"start": 452,
"text": "Takeda Pharmaceuticals North America, Inc."
} | {"gt_parses": [{"question" : "what is the name of the sponsor ?", "answer" : "Takeda Pharmaceuticals North America, Inc."}, {"question" : "what is the name of the sponsor ?", "answer" : "Takeda Pharmaceuticals North america , Inc."}]} |
train_366 | null | {
"de": "Was muss vor Beginn der Therapie mit Pioglitazon untersucht werden?",
"en": "what has to be investigated before starting pioglitazone therapy?",
"es": "¿Qué se debe investigar antes de iniciar el tratamiento con pioglitazona?",
"fr": "Qu'est-ce qui doit être étudié avant le début du traitement par la pioglitazone?",
"it": "Cosa deve essere studiato prima di iniziare la terapia con pioglitazone?"
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] | {
"match_score": 0.9615384630177515,
"matched_text": "Any macroscopic haematuria",
"start": 1236,
"text": "any macroscopic haematuria"
} | {"gt_parses": [{"question" : "what has to be investigated before starting pioglitazone therapy?", "answer" : "any macroscopic haematuria"}]} |
train_367 | null | {
"de": "Wie wurde häufig bei Patienten, die Actos in Kombination mit Insulin eingenommen haben, berichtet?",
"en": "what has been experienced commonly in patients taking actos in combination with insulin?",
"es": "¿Qué se ha experimentado con frecuencia en pacientes que toman actos en combinación con insulina?",
"fr": "Quelles ont été les expériences courantes chez les patients prenant des actos en association avec l'insuline?",
"it": "che cosa si è verificato comunemente nei pazienti che assumevano Actos in associazione con insulina?"
} | [
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"more",
"frequently",
"in",
"a",
"meta-analysis",
"of",
"controlled",
"clinical",
"trials",
"with",
"pioglitazone",
"(19",
"cases",
"from",
"12506",
"patients,",
"0.15%)",
"than",
"in",
"control",
"groups",
"(7",
"cases",
"from",
"10212",
"patients,",
"0:07%)",
"HR",
"2.64",
"(95%",
"CI",
"1.11-6.31,",
"P",
"0:029).",
"After",
"excluding",
"patients",
"in",
"whom",
"exposure",
"to",
"study",
"drug",
"was",
"less",
"than",
"one",
"year",
"at",
"the",
"time",
"of",
"diagnosis",
"of",
"bladder",
"cancer,",
"there",
"were",
"7",
"cases",
"(0.06%)",
"on",
"pioglitazone",
"and",
"2",
"cases",
"(0.02%)",
"in",
"control",
"groups.",
"Available",
"epidemiological",
"\"data",
"also",
"suggest",
"a",
"small",
"increased",
"risk",
"of",
"bladder",
"cancer",
"in",
"diabetic",
"patients",
"treated",
"with",
"pioglitazone,",
"in",
"particular",
"in",
"patients",
"treated",
"for",
"the",
"longest",
"durations",
"and",
"with",
"the",
"highest",
"cumulative",
"doses.",
"A",
"possible",
"risk",
"after",
"short",
"term",
"treatment",
"cannot",
"be",
"excluded.",
"Risk",
"factors",
"for",
"bladder",
"cancer",
"should",
"be",
"assessed",
"before",
"initiating",
"pioglitazone",
"treatment",
"(risks",
"include",
"age,",
"smoking",
"history,",
"exposure",
"to",
"some",
"occupational",
"or",
"chemotherapy",
"agents",
"e.g",
"cyclophosphamide",
"or",
"prior",
"radiation",
"treatment",
"in",
"the",
"pelvic",
"region).",
"Any",
"macroscopic",
"haematuria",
"should",
"be",
"investigated",
"before",
"starting",
"pioglitazone",
"therapy.",
"Patients",
"should",
"be",
"advised",
"to",
"promptly",
"seek",
"the",
"attention",
"of",
"their",
"physician",
"if",
"macroscopic",
"haematuria",
"or",
"other",
"symptoms",
"such",
"as",
"dysuria",
"or",
"urinary",
"urgency",
"develop",
"during",
"treatment.",
"Section",
"4.8",
"-",
"Undesirable",
"effects\"",
"Inclusion",
"of",
"bladder",
"cancer",
"as",
"an",
"uncommon",
"adverse",
"reaction",
"List",
"of",
"revisions",
"to",
"the",
"Patient",
"Information",
"Leaflet",
"Section",
"1",
"-",
"What",
"Actos/Competact",
"is",
"and",
"what",
"it",
"is",
"used",
"for",
"It",
"is",
"an",
"anti-diabetic",
"medicine",
"used",
"to",
"treat",
"type",
"2",
"(non-insulin",
"dependent)",
"diabetes",
"mellitus,",
"when",
"metformin",
"is",
"not",
"suitable",
"or",
"has",
"failed",
"to",
"work",
"adequately.",
"Your",
"doctor",
"will",
"check",
"whether",
"Actos/Competact",
"is",
"working",
"3",
"to",
"6",
"months",
"after",
"you",
"start",
"taking",
"it.",
"Actos",
"may",
"be",
"used",
"on",
"its",
"own",
"in",
"patients",
"who",
"are",
"unable",
"to",
"take",
"metformin,",
"and",
"where",
"treatment",
"with",
"diet",
"and",
"exercise",
"has",
"failed",
"to",
"control",
"blood",
"sugar",
"or",
"may",
"be",
"added",
"to",
"other",
"therapies",
"(such",
"as",
"metformin,",
"sulphonylurea",
"or",
"insulin)",
"which",
"have",
"failed",
"to",
"provide",
"sufficient",
"control",
"of",
"blood",
"sugar.",
"Section",
"2",
"-",
"Before",
"you",
"take",
"Actos/Competact",
"Do",
"not",
"take",
"Actos/Competact",
"if",
"you",
"have",
"or",
"have",
"ever",
"had",
"bladder",
"cancer.",
"if",
"you",
"have",
"blood",
"in",
"your",
"urine",
"that",
"your",
"doctor",
"has",
"not",
"checked",
"Section",
"4",
"-",
"Possible",
"side",
"effects",
"Heart",
"failure",
"has",
"been",
"experienced",
"commonly",
"(",
"1",
"to",
"10",
"users",
"in",
"100)",
"in",
"patients",
"taking",
"Actos",
"in",
"combination",
"with",
"insulin.",
"Symptoms",
"are",
"unusual",
"shortness",
"of",
"breath",
"or",
"rapid",
"increase",
"in",
"weight",
"or",
"localised",
"swelling",
"(oedema).",
"If",
"you",
"experience",
"any",
"of",
"these,",
"especially",
"if",
"you",
"are",
"over",
"the",
"age",
"of",
"65,",
"seek",
"medical",
"advice",
"straight",
"away.",
"Bladder",
"cancer",
"has",
"been",
"experienced",
"uncommonly",
"(I",
"to",
"10",
"users",
"in",
"1000)",
"in",
"patients",
"taking",
"Actos/Competact:",
"Signs",
"and",
"symptoms",
"include",
"blood",
"in",
"your",
"urine,",
"pain",
"when",
"urinating",
"or",
"a",
"sudden",
"need",
"to",
"urinate",
"If",
"you",
"experience",
"any",
"of",
"these,",
"talk",
"to",
"your",
"doctor",
"as",
"soon",
"as",
"possible",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-TYNANJ-00213202MAYAN",
"Source:",
"https://www.indup54dacooogsts.ucsf.edu/docs/psjf0226"
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"match_score": 1,
"matched_text": "Heart failure",
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train_368 | null | {
"de": "Welche Stiftung wird in diesem Dokument erwähnt?",
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"es": "¿Qué fundamento se menciona en este documento?",
"fr": "Quelle est la fondation mentionnée dans ce document?",
"it": "Quale fondamento è menzionato in questo documento?"
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train_369 | null | {
"de": "Unter welcher Abteilung ist die Cleveland Clinic Foundation tätig?",
"en": "Under which department , The Cleveland Clinic Foundation operates?",
"es": "¿Bajo qué departamento opera la Cleveland Clinic Foundation?",
"fr": "Sous quel département la Fondation des cliniques de Cleveland fonctionne-t-elle?",
"it": "In quale dipartimento opera la Cleveland Clinic Foundation?"
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] | {
"match_score": 1,
"matched_text": "Department of Cardiovascular Medicine",
"start": 215,
"text": "Department of Cardiovascular Medicine"
} | {"gt_parses": [{"question" : "Under which department , The Cleveland Clinic Foundation operates?", "answer" : "Department of Cardiovascular Medicine"}, {"question" : "Under which department , The Cleveland Clinic Foundation operates?", "answer" : "Department of Cardiovascular Medicine."}]} |
train_370 | null | {
"de": "Was ist in großen fetten Buchstaben unten geschrieben?",
"en": "What is written in big bold letters at the bottom?",
"es": "¿Qué está escrito en grandes letras en negrita en la parte inferior?",
"fr": "Qu'est-ce qui est écrit en grandes lettres audacieuses en bas?",
"it": "Cosa c'è scritto in lettere audaci in fondo?"
} | [
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"Lilly",
"&",
"Company",
"Date:",
"January",
"21,",
"1999",
"Att:",
"Mr.",
"Larry",
"Ellingson",
"From:",
"Kunio",
"Iwatani",
"Executive",
"Director",
"Actos",
"Product",
"Team",
"CC:",
"Mr.",
"Hamanaka,",
"TPA",
"Subject:",
"Upjohn",
"Matter",
"Dear",
"Mr.",
"Ellingson,",
"Enclosed",
"please",
"find",
"a",
"copy",
"of",
"Upjohn's",
"letter",
"to",
"US",
"FDA",
"dated",
"January",
"7,",
"1994.",
"In",
"the",
"letter",
"Upjohn",
"said",
"that",
"in",
"preliminary",
"clinical",
"evaluation",
"in",
"the",
"United",
"States,",
"pioglitazone",
"did",
"not",
"satisfy",
"Upjohn's",
"internal",
"requirement",
"for",
"reduction",
"blood",
"glucose;",
"therefore,",
"the",
"considerable",
"programs",
"required",
"for",
"development",
"of",
"pioglitazone",
"are",
"not",
"in",
"line",
"with",
"Upjohn's",
"business",
"needs.",
"-..",
"They",
"did",
"not",
"mention",
"about",
"safety",
"of",
"pioglitazone.",
"After",
"Upjohn's",
"decision,",
"Takeda",
"approached",
"FDA",
"and",
"consulted",
"whether",
"Takeda",
"might",
"go",
"further",
"the",
"clinical",
"development",
"works",
"on",
"pioglitazone.",
"Since",
"the",
"FDA's",
"response",
"was",
"positive",
"to",
"go",
"ahead,",
"Takeda",
"took",
"over",
"Upjohn's",
"works",
"and",
"finally",
"filed",
"NDA",
"on",
"January",
"15,",
"1999.",
"This",
"is",
"the",
"story",
"of",
"the",
"fact.",
"Although",
"there",
"may",
"be",
"rumors",
"about",
"the",
"reasons",
"of",
"Upjohn's",
"abandonment",
"of",
"pioglitazone",
"development,",
"specially",
"from",
"the",
"viewpoints",
"of",
"safety",
"issues,",
"it",
"might",
"be",
"advisable",
"for",
"us",
"to",
"keep",
"saying",
"that",
"Upjohn's",
"decision",
"is",
"based",
"on",
"JAN",
"21",
"'99",
"07:43",
"DALY",
"19",
"06",
"6204",
"2943",
"PAGE",
".",
"01",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"LLY-CRCARCH-00003000",
"Source:",
"https://www.indupbodsfoodonts.ucsf.edu/docs/nljf0226"
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"match_score": 1,
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"start": 1466,
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train_371 | null | {
"de": "Welches Arzneimittel wird zur Behandlung des Typ-2-Diabetes mellitus angewendet?",
"en": "Which medicine is used to treat type 2 diabetes mellitus?",
"es": "¿Qué medicamento se utiliza para tratar la diabetes mellitus tipo 2?",
"fr": "Quel médicament est utilisé pour traiter le diabète de type 2?",
"it": "Quale medicinale viene usato per trattare il diabete mellito di tipo 2?"
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"match_score": 1,
"matched_text": "Actos/Competact",
"start": 1671,
"text": "Actos/Competact"
} | {"gt_parses": [{"question" : "Which medicine is used to treat type 2 diabetes mellitus?", "answer" : "Actos/Competact"}]} |
train_372 | null | {
"de": "Wie viele Fälle von Blasenkrebs von 12506 Patienten wurden berichtet?",
"en": "How many cases of bladder cancer from 12506 patients were reported?",
"es": "¿Cuántos casos de cáncer de vejiga de 12506 pacientes fueron reportados?",
"fr": "Combien de cas de cancer de la vessie ont été rapportés chez 12506 patients?",
"it": "Quanti casi di cancro alla vescica sono stati segnalati da 12506 pazienti?"
} | [
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"65,",
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"a",
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"as",
"soon",
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"possible",
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"-",
"Subject",
"to",
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"Order",
"TAK-TYNANJ-00213202MAYAN",
"Source:",
"https://www.indup54dacooogsts.ucsf.edu/docs/psjf0226"
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"matched_text": "19 cases",
"start": 346,
"text": "19 cases"
} | {"gt_parses": [{"question" : "How many cases of bladder cancer from 12506 patients were reported?", "answer" : "19 cases"}]} |
train_373 | null | {
"de": "Wie lautet die Postfachnummer?",
"en": "What is the PO Box number?",
"es": "¿Cuál es el número de la casilla de correos?",
"fr": "Quel est le numéro de la boîte postale?",
"it": "Qual è il numero della casella postale?"
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train_374 | null | {
"de": "was ist das IND mumber (wenn zuvor zugewiesen )?",
"en": "what is the IND mumber (if previously assigned ) ?",
"es": "¿Qué es el IND mumber (si se ha asignado previamente )?",
"fr": "qu'est-ce que l'IND mumber (si précédemment assigné )?",
"it": "che cos'è il legname IND (se precedentemente assegnato)?"
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train_376 | null | {
"de": "Wie lautet das Datum der Einreichung?",
"en": "what is the date of submission ?",
"es": "¿Cuál es la fecha de presentación?",
"fr": "Quelle est la date de présentation?",
"it": "Qual è la data di presentazione?"
} | [
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train_377 | null | {
"de": "was ist der Name(n) des Arzneimittels (enthält alle verfügbaren Namen: Trade, Generic, Chemical, Code)?",
"en": "what is the Name(s) of drug (include all available names: Trade , Generic, Chemical, Code)?",
"es": "¿Cuál es el(los) nombre(s) de la droga (incluye todos los nombres disponibles: Comercio, Genérico, Química, Código)?",
"fr": "Quel est le(s) nom(s) du(des) médicament(s) (comprend(nt) tous les noms disponibles : commerce, générique, chimique, code)?",
"it": "Qual è il nome (i) del farmaco (includere tutti i nomi disponibili: Commercio, Generico, Chimico, Codice)?"
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"match_score": 0.9200000031999999,
"matched_text": "ACTOS@ (pioglitazone HCI ",
"start": 782,
"text": "ACTOS (pioglitazone HCI)"
} | {"gt_parses": [{"question" : "what is the Name(s) of drug (include all available names: Trade , Generic, Chemical, Code)?", "answer" : "ACTOS (pioglitazone HCI)"}, {"question" : "what is the Name(s) of drug (include all available names: Trade , Generic, Chemical, Code)?", "answer" : "ACTOS (Pioglitazone HCI)"}]} |
train_378 | null | {
"de": "Was ist die Steuer-ID in diesem Dokument erwähnt?",
"en": "What is the Tax ID mentioned in this document?",
"es": "¿Cuál es la identificación fiscal mencionada en este documento?",
"fr": "Quel est le numéro d'identification fiscal mentionné dans ce document?",
"it": "Che cosa è l'ID fiscale menzionato in questo documento?"
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"match_score": 1,
"matched_text": "34-0714585",
"start": 319,
"text": "34-0714585"
} | {"gt_parses": [{"question" : "What is the Tax ID mentioned in this document?", "answer" : "34-0714585"}]} |
train_379 | null | {
"de": "was ist das Formular genehmigt : OMB Nein",
"en": "what is the form approved : OMB No",
"es": "Cuál es el formulario aprobado : No OMB",
"fr": "quel est le formulaire approuvé : OMB Non",
"it": "Qual è il modulo approvato : OMB No"
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"fr": "Quel est le mot écrit en gras en haut du document?",
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train_381 | null | {
"de": "Wie lautet das erwähnte Datum?",
"en": "What is the date mentioned?",
"es": "¿Cuál es la fecha mencionada?",
"fr": "Quelle est la date mentionnée?",
"it": "Qual è la data indicata?"
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] | {
"match_score": 0.866666675555555,
"matched_text": "19 January 2012",
"start": 7,
"text": "19th January 2012"
} | {"gt_parses": [{"question" : "What is the date mentioned?", "answer" : "19th January 2012"}]} |
train_382 | null | {
"de": "Wie lautet der Name der Pharmazeutika?",
"en": "what is the name of pharmaceuticals ?",
"es": "¿Cuál es el nombre de los productos farmacéuticos?",
"fr": "Quel est le nom des produits pharmaceutiques?",
"it": "Qual è il nome dei prodotti farmaceutici?"
} | [
"Takeda Pharmaceuticals North America, Inc.",
"TAkeda pharmaceuticals North America ,INc."
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"L.",
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"Dear",
"Ms.",
"Haskins:",
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"submitted",
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"15,",
"1999,",
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"9,",
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"our",
"November",
"13,",
"2002,",
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"We",
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"and",
"have",
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"that",
"removal",
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"the",
"clinical",
"hold",
"is",
"not",
"warranted.",
"We",
"acknowledge",
"your",
"agreement",
"to",
"monitor",
"for",
"bladder",
"tumors",
"in",
"your",
"clinical",
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"and",
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"consent",
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"do",
"not",
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"are",
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"you",
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"required",
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"submit",
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"to",
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"response",
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"-",
"Subject",
"to",
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"Order",
"TAK-INDNDA-01577085",
"in",
"MDL",
"on",
"01/31/13",
"Source:",
"https://www.induptrygg-ooooits.ucsf.edu/docs/xyjf0226"
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] | {
"match_score": 1,
"matched_text": "Takeda Pharmaceuticals North America, Inc.",
"start": 159,
"text": "Takeda Pharmaceuticals North America, Inc."
} | {"gt_parses": [{"question" : "what is the name of pharmaceuticals ?", "answer" : "Takeda Pharmaceuticals North America, Inc."}, {"question" : "what is the name of pharmaceuticals ?", "answer" : "TAkeda pharmaceuticals North America ,INc."}]} |
train_383 | null | {
"de": "an wen dieser Brief geschrieben wird?",
"en": "to whom this letter is written ?",
"es": "¿A quién está escrita esta carta?",
"fr": "à qui cette lettre est-elle écrite?",
"it": "a chi è scritta questa lettera?"
} | [
"Janet L. Haskins",
"janet L. haskins",
"Ms. Haskins"
] | [
"DEPARTMENT",
"OF",
"HEALTH",
"&",
"HUMAN",
"SERVICES",
"Public",
"Health",
"Service",
"Food",
"and",
"Drug",
"Administration",
"Rockville,",
"MD",
"20857",
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"DEPARTMENT",
"Takeda",
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"Attention:",
"Janet",
"L.",
"Haskin",
"JUN",
"1",
"6",
"2003",
"Manager,",
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"475",
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"Pharmaceuticals",
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"Lincolnshire,",
"IL",
"60069",
"Dear",
"Ms.",
"Haskins:",
"Please",
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"to",
"your",
"Investigational",
"New",
"Drug",
"Application",
"(IND)",
"submitted",
"January",
"15,",
"1999,",
"under",
"section",
"505(i)",
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"the",
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"Food,",
"Drug,",
"and",
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"Tablets,",
"15",
"mg,",
"30",
"mg",
"and",
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"also",
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"your",
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"dated",
"May",
"8,",
"2003",
"(serial",
"#",
"525),",
"received",
"on",
"May",
"9,",
"2003,",
"that",
"provided",
"a",
"response",
"to",
"our",
"November",
"13,",
"2002,",
"letter",
"which",
"cited",
"the",
"reasons",
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"protocol",
"was",
"placed",
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"clinical",
"hold",
"and",
"the",
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"resolve",
"the",
"clinical",
"hold",
"issues.",
"We",
"have",
"completed",
"the",
"review",
"of",
"your",
"submission",
"and",
"have",
"concluded",
"that",
"removal",
"of",
"the",
"clinical",
"hold",
"is",
"not",
"warranted.",
"We",
"acknowledge",
"your",
"agreement",
"to",
"monitor",
"for",
"bladder",
"tumors",
"in",
"your",
"clinical",
"studies,",
"and",
"to",
"amend",
"the",
"label",
"and",
"consent",
"documents.",
"However,",
"until",
"further",
"information",
"on",
"bladder",
"effects",
"from",
"ongoing",
"studies",
"is",
"available,",
"we",
"do",
"not",
"believe",
"studies",
"in",
"pediatric",
"patients",
"are",
"warranted.",
"Until",
"you",
"have",
"submitted",
"the",
"required",
"information",
"and",
"we",
"notify",
"you",
"that",
"you",
"may",
"initiate",
"trials,",
"this",
"IND",
"remains",
"on",
"clinical",
"hold",
"and",
"you",
"may",
"not",
"legally",
"conduct",
"clinical",
"studies",
"under",
"it.",
"Please",
"identify",
"your",
"response",
"to",
"the",
"clinical",
"hold",
"issues",
"as",
"a",
"\"CLINICAL",
"HOLD",
"COMPLETE",
"RESPONSE.\"",
"To",
"facilitate",
"a",
"response",
"to",
"your",
"submission,",
"submit",
"this",
"information",
"in",
"triplicate",
"to",
"the",
"IND.",
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"addition,",
"send",
"a",
"copy",
"of",
"the",
"cover",
"letter",
"to",
"Ms.",
"Jena",
"Weber.",
"Following",
"receipt",
"of",
"your",
"complete",
"response",
"to",
"these",
"issues,",
"we",
"will",
"notify",
"you",
"of",
"our",
"decision",
"within",
"30",
"days.",
"424",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-INDNDA-01577085",
"in",
"MDL",
"on",
"01/31/13",
"Source:",
"https://www.induptrygg-ooooits.ucsf.edu/docs/xyjf0226"
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] | {
"match_score": 0.9375000039062498,
"matched_text": "Janet L. Haskin ",
"start": 213,
"text": "Janet L. Haskins"
} | {"gt_parses": [{"question" : "to whom this letter is written ?", "answer" : "Janet L. Haskins"}, {"question" : "to whom this letter is written ?", "answer" : "janet L. haskins"}, {"question" : "to whom this letter is written ?", "answer" : "Ms. Haskins"}]} |
train_384 | null | {
"de": "Wann hat die Abteilung für Regulatorische Angelegenheiten diesen Brief erhalten?",
"en": "When did Regulatory affairs department receive this letter?",
"es": "¿Cuándo recibió el Departamento de Asuntos Regulatorios esta carta?",
"fr": "Quand le ministère des Affaires réglementaires a-t-il reçu cette lettre?",
"it": "Quando ha ricevuto questa lettera il Dipartimento Affari Regolatori?"
} | [
"JUN 16 2003"
] | [
"DEPARTMENT",
"OF",
"HEALTH",
"&",
"HUMAN",
"SERVICES",
"Public",
"Health",
"Service",
"Food",
"and",
"Drug",
"Administration",
"Rockville,",
"MD",
"20857",
"IND",
"33,729",
"RECEIVED",
"REGULATORY",
"AFFAIRS",
"DEPARTMENT",
"Takeda",
"Pharmaceuticals",
"North",
"America,",
"Inc.",
"Attention:",
"Janet",
"L.",
"Haskin",
"JUN",
"1",
"6",
"2003",
"Manager,",
"Regulatory",
"Affairs",
"475",
"Half",
"Day",
"Road,",
"Suite",
"500",
"Takeda",
"Pharmaceuticals",
"North",
"America,",
"Ins",
"Lincolnshire,",
"IL",
"60069",
"Dear",
"Ms.",
"Haskins:",
"Please",
"refer",
"to",
"your",
"Investigational",
"New",
"Drug",
"Application",
"(IND)",
"submitted",
"January",
"15,",
"1999,",
"under",
"section",
"505(i)",
"of",
"the",
"Federal",
"Food,",
"Drug,",
"and",
"Cosmetic",
"Act",
"for",
"Actos",
"(pioglitazone",
"HCI)",
"Tablets,",
"15",
"mg,",
"30",
"mg",
"and",
"45",
"mg",
"We",
"also",
"refer",
"to",
"your",
"amendment",
"dated",
"May",
"8,",
"2003",
"(serial",
"#",
"525),",
"received",
"on",
"May",
"9,",
"2003,",
"that",
"provided",
"a",
"response",
"to",
"our",
"November",
"13,",
"2002,",
"letter",
"which",
"cited",
"the",
"reasons",
"this",
"protocol",
"was",
"placed",
"on",
"clinical",
"hold",
"and",
"the",
"information",
"needed",
"to",
"resolve",
"the",
"clinical",
"hold",
"issues.",
"We",
"have",
"completed",
"the",
"review",
"of",
"your",
"submission",
"and",
"have",
"concluded",
"that",
"removal",
"of",
"the",
"clinical",
"hold",
"is",
"not",
"warranted.",
"We",
"acknowledge",
"your",
"agreement",
"to",
"monitor",
"for",
"bladder",
"tumors",
"in",
"your",
"clinical",
"studies,",
"and",
"to",
"amend",
"the",
"label",
"and",
"consent",
"documents.",
"However,",
"until",
"further",
"information",
"on",
"bladder",
"effects",
"from",
"ongoing",
"studies",
"is",
"available,",
"we",
"do",
"not",
"believe",
"studies",
"in",
"pediatric",
"patients",
"are",
"warranted.",
"Until",
"you",
"have",
"submitted",
"the",
"required",
"information",
"and",
"we",
"notify",
"you",
"that",
"you",
"may",
"initiate",
"trials,",
"this",
"IND",
"remains",
"on",
"clinical",
"hold",
"and",
"you",
"may",
"not",
"legally",
"conduct",
"clinical",
"studies",
"under",
"it.",
"Please",
"identify",
"your",
"response",
"to",
"the",
"clinical",
"hold",
"issues",
"as",
"a",
"\"CLINICAL",
"HOLD",
"COMPLETE",
"RESPONSE.\"",
"To",
"facilitate",
"a",
"response",
"to",
"your",
"submission,",
"submit",
"this",
"information",
"in",
"triplicate",
"to",
"the",
"IND.",
"In",
"addition,",
"send",
"a",
"copy",
"of",
"the",
"cover",
"letter",
"to",
"Ms.",
"Jena",
"Weber.",
"Following",
"receipt",
"of",
"your",
"complete",
"response",
"to",
"these",
"issues,",
"we",
"will",
"notify",
"you",
"of",
"our",
"decision",
"within",
"30",
"days.",
"424",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-INDNDA-01577085",
"in",
"MDL",
"on",
"01/31/13",
"Source:",
"https://www.induptrygg-ooooits.ucsf.edu/docs/xyjf0226"
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train_385 | null | {
"de": "An wen wurde dieser Brief geschrieben?",
"en": "To whom was this letter written?",
"es": "¿A quién escribió esta carta?",
"fr": "À qui cette lettre a-t-elle été écrite?",
"it": "A chi è stata scritta questa lettera?"
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] | {
"match_score": 1,
"matched_text": "Healthcare Professional",
"start": 30,
"text": "Healthcare Professional"
} | {"gt_parses": [{"question" : "To whom was this letter written?", "answer" : "Healthcare Professional"}]} |
train_386 | null | {
"de": "Was ist der fünfte Punkt?",
"en": "What is the fifth point?",
"es": "¿Cuál es el quinto punto?",
"fr": "Quel est le cinquième point?",
"it": "Qual è il quinto punto?"
} | [
"WAC and AWP generally;",
"WAC AND AWP generally;"
] | [
"3.",
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"but",
"not",
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"to,",
"RedBook,",
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"Data",
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"products;",
"5.",
"WAC",
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"AWP",
"generally;",
"6.",
"Medicare",
"and",
"Medicaid",
"reimbursement",
"for",
"TPNA",
"pharmaceutical",
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"generally;",
"7.",
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"Best",
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"marketing,",
"and",
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"if",
"any,",
"relating",
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"\"E-mail",
"Management",
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"Retention.\"",
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"structure",
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"and",
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"slides,",
"etc.)",
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"you",
"must",
"follow",
"the",
"requirements",
"of",
"BOP,",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention\"",
"for",
"the",
"retention",
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"materials,",
"and",
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"\"Best",
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"Physical",
"And",
"Electronic",
"Storage",
"Of",
"Materials",
"That",
"Must",
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"Retained",
"For",
"Legal",
"Reasons....\"",
"IN",
"ALL",
"CASES,",
"THE",
"FOLLOWING",
"INSTRUCTIONS",
"APPLY",
"TO",
"DOCUMENTS,",
"MATERIALS,",
"INFORMATION,",
"AND",
"THINGS,",
"IN",
"HARD",
"COPY",
"OR",
"ELECTRONIC",
"FORMAT,",
"THAT",
"ARE",
"REQUIRED",
"TO",
"BE",
"RETAINED",
"PURSUANT",
"TO",
"THIS",
"LEGAL",
"HOLD.",
"Last",
"printed",
"11/30/2012",
"4:28:00",
"AM",
"20122830-042845",
"doc",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-RIM30b6-00000665",
"Source:",
"https://[email protected]/docs/frjf0226"
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] | {
"match_score": 1,
"matched_text": "WAC and AWP generally;",
"start": 327,
"text": "WAC and AWP generally;"
} | {"gt_parses": [{"question" : "What is the fifth point?", "answer" : "WAC and AWP generally;"}, {"question" : "What is the fifth point?", "answer" : "WAC AND AWP generally;"}]} |
train_387 | null | {
"de": "Bildungsstipendien für welche Produkte?",
"en": "Education grants regarding which products?",
"es": "¿Subvenciones de educación con respecto a qué productos?",
"fr": "Bourses d'études pour quels produits?",
"it": "Borse di studio relative a quali prodotti?"
} | [
"TPNA",
"TPNA products"
] | [
"3.",
"Reports",
"to",
"any",
"third",
"party,",
"including,",
"but",
"not",
"limited",
"to,",
"RedBook,",
"First",
"Data",
"Bank,",
"Blue",
"Book,",
"Medi-Span,",
"or",
"other",
"price",
"reporting",
"service,",
"regarding",
"prices",
"for",
"TPNA",
"products;",
"4.",
"Communications",
"with",
"RedBook,",
"First",
"Data",
"Bank,",
"Blue",
"Book,",
"Medi-Span,",
"or",
"other",
"pricing",
"reporting",
"services,",
"regarding",
"prices",
"for",
"TPNA",
"products;",
"5.",
"WAC",
"and",
"AWP",
"generally;",
"6.",
"Medicare",
"and",
"Medicaid",
"reimbursement",
"for",
"TPNA",
"pharmaceutical",
"products",
"generally;",
"7.",
"Calculation",
"and",
"reporting",
"of",
"Average",
"Manufacturer",
"Price",
"and",
"Best",
"Price",
"for",
"TPNA",
"products,",
"as",
"may",
"be",
"required",
"by",
"federal",
"and",
"state",
"laws",
"and",
"regulations;",
"8.",
"Communications",
"with",
"any",
"state",
"or",
"federal",
"governmental",
"agency",
"regarding",
"TPNA's",
"participation",
"in",
"the",
"Medicaid",
"program;",
"9.",
"Invoices,",
"internal",
"sales",
"projections,",
"and",
"profit",
"statements",
"that",
"indicate",
"the",
"price",
"TPNA",
"paid",
"for",
"its",
"products",
"and",
"the",
"profits",
"IPNA",
"made",
"based",
"upon",
"sales",
"of",
"these",
"products;",
"10.",
"Meetings",
"at",
"which",
"sales,",
"marketing,",
"and",
"pricing",
"decisions",
"were",
"discussed;",
"11.",
"Communications",
"with",
"providers,",
"if",
"any,",
"relating",
"to",
"the",
"use",
"of",
"the",
"terms",
"\"spread\"",
"or",
"\"profit\"",
"in",
"the",
"context",
"of",
"the",
"sale",
"or",
"marketing",
"of",
"TPNA",
"products;",
"12.",
"Marketing",
"materials",
"(including",
"proposed",
"materials),",
"if",
"any,",
"relating",
"to",
"the",
"cost",
"and",
"\"spread\"",
"for",
"TPNA",
"products;",
"13.",
"Provision",
"of",
"free",
"samples",
"or",
"nominally",
"priced",
"TPNA",
"products",
"to",
"any",
"providers;",
"and",
"14.",
"Educational",
"grants",
"regarding",
"TPNA",
"products;",
"These",
"requirements",
"are",
"related",
"to",
"all",
"TPNA",
"marketed",
"products.",
"Each",
"Takeda",
"Employee",
"or",
"Contractor",
"shall",
"create",
"an",
"Outlook",
"Folder",
"entitled",
"\"AWP\"",
"beneath",
"the",
"\"Legal",
"Hold\"",
"folder",
"provided",
"as",
"part",
"of",
"the",
"implementation",
"of",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention.\"",
"Contact",
"the",
"Help",
"Desk",
"if",
"your",
"Outlook",
"file",
"folder",
"structure",
"does",
"not",
"contain",
"a",
"\"Legal",
"Hold\"",
"folder.",
"This",
"means",
"that",
"all",
"documents,",
"materials,",
"and",
"computer",
"files",
"(including",
"e-mails,",
"word",
"processing",
"documents,",
"slides,",
"etc.)",
"falling",
"into",
"this",
"category",
"must",
"continue",
"to",
"be",
"maintained",
"until",
"you",
"are",
"informed",
"otherwise,",
"regardless",
"of",
"the",
"specified",
"record",
"retention",
"period",
"that",
"would",
"apply",
"to",
"such",
"materials",
"under",
"Takeda's",
"current",
"Records",
"Retention",
"Schedules",
"and",
"program.",
"You",
"are",
"reminded",
"that",
"you",
"must",
"follow",
"the",
"requirements",
"of",
"BOP,",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention\"",
"for",
"the",
"retention",
"of",
"electronic",
"materials,",
"and",
"the",
"\"Best",
"Practices",
"For",
"The",
"Physical",
"And",
"Electronic",
"Storage",
"Of",
"Materials",
"That",
"Must",
"Be",
"Retained",
"For",
"Legal",
"Reasons....\"",
"IN",
"ALL",
"CASES,",
"THE",
"FOLLOWING",
"INSTRUCTIONS",
"APPLY",
"TO",
"DOCUMENTS,",
"MATERIALS,",
"INFORMATION,",
"AND",
"THINGS,",
"IN",
"HARD",
"COPY",
"OR",
"ELECTRONIC",
"FORMAT,",
"THAT",
"ARE",
"REQUIRED",
"TO",
"BE",
"RETAINED",
"PURSUANT",
"TO",
"THIS",
"LEGAL",
"HOLD.",
"Last",
"printed",
"11/30/2012",
"4:28:00",
"AM",
"20122830-042845",
"doc",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-RIM30b6-00000665",
"Source:",
"https://[email protected]/docs/frjf0226"
] | [
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178.8235321044922,
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] | {
"match_score": 1,
"matched_text": "TPNA",
"start": 165,
"text": "TPNA"
} | {"gt_parses": [{"question" : "Education grants regarding which products?", "answer" : "TPNA"}, {"question" : "Education grants regarding which products?", "answer" : "TPNA products"}]} |
train_388 | null | {
"de": "Wie lautet das Datum, an dem dieses Dokument zuletzt gedruckt wurde?",
"en": "What is the date this document was last printed?",
"es": "¿Cuál es la fecha de la última impresión de este documento?",
"fr": "Quelle est la date à laquelle ce document a été imprimé pour la dernière fois?",
"it": "Qual è la data in cui questo documento è stato stampato l'ultima volta?"
} | [
"11/30/2012",
"11/30/2012 4:28:00 AM"
] | [
"3.",
"Reports",
"to",
"any",
"third",
"party,",
"including,",
"but",
"not",
"limited",
"to,",
"RedBook,",
"First",
"Data",
"Bank,",
"Blue",
"Book,",
"Medi-Span,",
"or",
"other",
"price",
"reporting",
"service,",
"regarding",
"prices",
"for",
"TPNA",
"products;",
"4.",
"Communications",
"with",
"RedBook,",
"First",
"Data",
"Bank,",
"Blue",
"Book,",
"Medi-Span,",
"or",
"other",
"pricing",
"reporting",
"services,",
"regarding",
"prices",
"for",
"TPNA",
"products;",
"5.",
"WAC",
"and",
"AWP",
"generally;",
"6.",
"Medicare",
"and",
"Medicaid",
"reimbursement",
"for",
"TPNA",
"pharmaceutical",
"products",
"generally;",
"7.",
"Calculation",
"and",
"reporting",
"of",
"Average",
"Manufacturer",
"Price",
"and",
"Best",
"Price",
"for",
"TPNA",
"products,",
"as",
"may",
"be",
"required",
"by",
"federal",
"and",
"state",
"laws",
"and",
"regulations;",
"8.",
"Communications",
"with",
"any",
"state",
"or",
"federal",
"governmental",
"agency",
"regarding",
"TPNA's",
"participation",
"in",
"the",
"Medicaid",
"program;",
"9.",
"Invoices,",
"internal",
"sales",
"projections,",
"and",
"profit",
"statements",
"that",
"indicate",
"the",
"price",
"TPNA",
"paid",
"for",
"its",
"products",
"and",
"the",
"profits",
"IPNA",
"made",
"based",
"upon",
"sales",
"of",
"these",
"products;",
"10.",
"Meetings",
"at",
"which",
"sales,",
"marketing,",
"and",
"pricing",
"decisions",
"were",
"discussed;",
"11.",
"Communications",
"with",
"providers,",
"if",
"any,",
"relating",
"to",
"the",
"use",
"of",
"the",
"terms",
"\"spread\"",
"or",
"\"profit\"",
"in",
"the",
"context",
"of",
"the",
"sale",
"or",
"marketing",
"of",
"TPNA",
"products;",
"12.",
"Marketing",
"materials",
"(including",
"proposed",
"materials),",
"if",
"any,",
"relating",
"to",
"the",
"cost",
"and",
"\"spread\"",
"for",
"TPNA",
"products;",
"13.",
"Provision",
"of",
"free",
"samples",
"or",
"nominally",
"priced",
"TPNA",
"products",
"to",
"any",
"providers;",
"and",
"14.",
"Educational",
"grants",
"regarding",
"TPNA",
"products;",
"These",
"requirements",
"are",
"related",
"to",
"all",
"TPNA",
"marketed",
"products.",
"Each",
"Takeda",
"Employee",
"or",
"Contractor",
"shall",
"create",
"an",
"Outlook",
"Folder",
"entitled",
"\"AWP\"",
"beneath",
"the",
"\"Legal",
"Hold\"",
"folder",
"provided",
"as",
"part",
"of",
"the",
"implementation",
"of",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention.\"",
"Contact",
"the",
"Help",
"Desk",
"if",
"your",
"Outlook",
"file",
"folder",
"structure",
"does",
"not",
"contain",
"a",
"\"Legal",
"Hold\"",
"folder.",
"This",
"means",
"that",
"all",
"documents,",
"materials,",
"and",
"computer",
"files",
"(including",
"e-mails,",
"word",
"processing",
"documents,",
"slides,",
"etc.)",
"falling",
"into",
"this",
"category",
"must",
"continue",
"to",
"be",
"maintained",
"until",
"you",
"are",
"informed",
"otherwise,",
"regardless",
"of",
"the",
"specified",
"record",
"retention",
"period",
"that",
"would",
"apply",
"to",
"such",
"materials",
"under",
"Takeda's",
"current",
"Records",
"Retention",
"Schedules",
"and",
"program.",
"You",
"are",
"reminded",
"that",
"you",
"must",
"follow",
"the",
"requirements",
"of",
"BOP,",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention\"",
"for",
"the",
"retention",
"of",
"electronic",
"materials,",
"and",
"the",
"\"Best",
"Practices",
"For",
"The",
"Physical",
"And",
"Electronic",
"Storage",
"Of",
"Materials",
"That",
"Must",
"Be",
"Retained",
"For",
"Legal",
"Reasons....\"",
"IN",
"ALL",
"CASES,",
"THE",
"FOLLOWING",
"INSTRUCTIONS",
"APPLY",
"TO",
"DOCUMENTS,",
"MATERIALS,",
"INFORMATION,",
"AND",
"THINGS,",
"IN",
"HARD",
"COPY",
"OR",
"ELECTRONIC",
"FORMAT,",
"THAT",
"ARE",
"REQUIRED",
"TO",
"BE",
"RETAINED",
"PURSUANT",
"TO",
"THIS",
"LEGAL",
"HOLD.",
"Last",
"printed",
"11/30/2012",
"4:28:00",
"AM",
"20122830-042845",
"doc",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-RIM30b6-00000665",
"Source:",
"https://[email protected]/docs/frjf0226"
] | [
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"start": 2576,
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} | {"gt_parses": [{"question" : "What is the date this document was last printed?", "answer" : "11/30/2012"}, {"question" : "What is the date this document was last printed?", "answer" : "11/30/2012 4:28:00 AM"}]} |
train_389 | null | {
"de": "An wen muss eine Kopie des Anschreibens geschickt werden?",
"en": "To whom a copy of cover letter has to be sent ?",
"es": "¿A quién hay que enviar una copia de la carta de presentación?",
"fr": "À qui une copie de la lettre d'accompagnement doit-elle être envoyée?",
"it": "A chi deve essere inviata una copia della lettera di accompagnamento?"
} | [
"Ms. Jens Weber"
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"this",
"protocol",
"was",
"placed",
"on",
"clinical",
"hold",
"and",
"the",
"information",
"needed",
"to",
"resolve",
"the",
"clinical",
"hold",
"issues.",
"We",
"have",
"completed",
"the",
"review",
"of",
"your",
"submission",
"and",
"have",
"concluded",
"that",
"removal",
"of",
"the",
"clinical",
"hold",
"is",
"not",
"warranted.",
"We",
"acknowledge",
"your",
"agreement",
"to",
"monitor",
"for",
"bladder",
"tumors",
"in",
"your",
"clinical",
"studies,",
"and",
"to",
"amend",
"the",
"label",
"and",
"consent",
"documents.",
"However,",
"until",
"further",
"information",
"on",
"bladder",
"effects",
"from",
"ongoing",
"studies",
"is",
"available,",
"we",
"do",
"not",
"believe",
"studies",
"in",
"pediatric",
"patients",
"are",
"warranted.",
"Until",
"you",
"have",
"submitted",
"the",
"required",
"information",
"and",
"we",
"notify",
"you",
"that",
"you",
"may",
"initiate",
"trials,",
"this",
"IND",
"remains",
"on",
"clinical",
"hold",
"and",
"you",
"may",
"not",
"legally",
"conduct",
"clinical",
"studies",
"under",
"it.",
"Please",
"identify",
"your",
"response",
"to",
"the",
"clinical",
"hold",
"issues",
"as",
"a",
"\"CLINICAL",
"HOLD",
"COMPLETE",
"RESPONSE.\"",
"To",
"facilitate",
"a",
"response",
"to",
"your",
"submission,",
"submit",
"this",
"information",
"in",
"triplicate",
"to",
"the",
"IND.",
"In",
"addition,",
"send",
"a",
"copy",
"of",
"the",
"cover",
"letter",
"to",
"Ms.",
"Jena",
"Weber.",
"Following",
"receipt",
"of",
"your",
"complete",
"response",
"to",
"these",
"issues,",
"we",
"will",
"notify",
"you",
"of",
"our",
"decision",
"within",
"30",
"days.",
"424",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-INDNDA-01577085",
"in",
"MDL",
"on",
"01/31/13",
"Source:",
"https://www.induptrygg-ooooits.ucsf.edu/docs/xyjf0226"
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] | {
"match_score": 0.9285714336734691,
"matched_text": "Ms. Jena Weber",
"start": 1714,
"text": "Ms. Jens Weber"
} | {"gt_parses": [{"question" : "To whom a copy of cover letter has to be sent ?", "answer" : "Ms. Jens Weber"}]} |
train_390 | null | {
"de": "Welche Erstattung für TPNA-Arzneimittel wird in der Regel gewährt?",
"en": "Which reimbursement for TPNA pharmaceutical products is generally given?",
"es": "¿Qué reembolso para los productos farmacéuticos TPNA se da generalmente?",
"fr": "Quel remboursement pour les produits pharmaceutiques TPNA est généralement accordé?",
"it": "Quale rimborso per i prodotti farmaceutici TPNA è generalmente dato?"
} | [
"Medicare and Medicaid"
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"and",
"profit",
"statements",
"that",
"indicate",
"the",
"price",
"TPNA",
"paid",
"for",
"its",
"products",
"and",
"the",
"profits",
"IPNA",
"made",
"based",
"upon",
"sales",
"of",
"these",
"products;",
"10.",
"Meetings",
"at",
"which",
"sales,",
"marketing,",
"and",
"pricing",
"decisions",
"were",
"discussed;",
"11.",
"Communications",
"with",
"providers,",
"if",
"any,",
"relating",
"to",
"the",
"use",
"of",
"the",
"terms",
"\"spread\"",
"or",
"\"profit\"",
"in",
"the",
"context",
"of",
"the",
"sale",
"or",
"marketing",
"of",
"TPNA",
"products;",
"12.",
"Marketing",
"materials",
"(including",
"proposed",
"materials),",
"if",
"any,",
"relating",
"to",
"the",
"cost",
"and",
"\"spread\"",
"for",
"TPNA",
"products;",
"13.",
"Provision",
"of",
"free",
"samples",
"or",
"nominally",
"priced",
"TPNA",
"products",
"to",
"any",
"providers;",
"and",
"14.",
"Educational",
"grants",
"regarding",
"TPNA",
"products;",
"These",
"requirements",
"are",
"related",
"to",
"all",
"TPNA",
"marketed",
"products.",
"Each",
"Takeda",
"Employee",
"or",
"Contractor",
"shall",
"create",
"an",
"Outlook",
"Folder",
"entitled",
"\"AWP\"",
"beneath",
"the",
"\"Legal",
"Hold\"",
"folder",
"provided",
"as",
"part",
"of",
"the",
"implementation",
"of",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention.\"",
"Contact",
"the",
"Help",
"Desk",
"if",
"your",
"Outlook",
"file",
"folder",
"structure",
"does",
"not",
"contain",
"a",
"\"Legal",
"Hold\"",
"folder.",
"This",
"means",
"that",
"all",
"documents,",
"materials,",
"and",
"computer",
"files",
"(including",
"e-mails,",
"word",
"processing",
"documents,",
"slides,",
"etc.)",
"falling",
"into",
"this",
"category",
"must",
"continue",
"to",
"be",
"maintained",
"until",
"you",
"are",
"informed",
"otherwise,",
"regardless",
"of",
"the",
"specified",
"record",
"retention",
"period",
"that",
"would",
"apply",
"to",
"such",
"materials",
"under",
"Takeda's",
"current",
"Records",
"Retention",
"Schedules",
"and",
"program.",
"You",
"are",
"reminded",
"that",
"you",
"must",
"follow",
"the",
"requirements",
"of",
"BOP,",
"CORP-B-019",
"\"E-mail",
"Management",
"and",
"Retention\"",
"for",
"the",
"retention",
"of",
"electronic",
"materials,",
"and",
"the",
"\"Best",
"Practices",
"For",
"The",
"Physical",
"And",
"Electronic",
"Storage",
"Of",
"Materials",
"That",
"Must",
"Be",
"Retained",
"For",
"Legal",
"Reasons....\"",
"IN",
"ALL",
"CASES,",
"THE",
"FOLLOWING",
"INSTRUCTIONS",
"APPLY",
"TO",
"DOCUMENTS,",
"MATERIALS,",
"INFORMATION,",
"AND",
"THINGS,",
"IN",
"HARD",
"COPY",
"OR",
"ELECTRONIC",
"FORMAT,",
"THAT",
"ARE",
"REQUIRED",
"TO",
"BE",
"RETAINED",
"PURSUANT",
"TO",
"THIS",
"LEGAL",
"HOLD.",
"Last",
"printed",
"11/30/2012",
"4:28:00",
"AM",
"20122830-042845",
"doc",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-RIM30b6-00000665",
"Source:",
"https://[email protected]/docs/frjf0226"
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train_391 | null | {
"de": "Wie lautet die Bezeichnung von Alfonso T. Perez, M.D.?",
"en": "What is the designation of Alfonso T. Perez, M.D.?",
"es": "¿Cuál es la designación de Alfonso T. Pérez, M.D.?",
"fr": "Quelle est la désignation d'Alfonso T. Perez, M.D.?",
"it": "Qual è la designazione di Alfonso T. Perez, MD?"
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train_394 | null | {
"de": "Wie lautet die oben geschriebene Nummer TAK-INDNDA-01577086?",
"en": "What is the number written above TAK-INDNDA-01577086?",
"es": "¿Cuál es el número escrito arriba de TAK-INDNDA-01577086?",
"fr": "Quel est le numéro écrit ci-dessus TAK-INDNDA-01577086?",
"it": "Qual è il numero scritto sopra TAK-INDNDA-01577086?"
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train_395 | null | {
"de": "Wie lautet die Kontaktnummer von Frau Jena Weber, Regulatory Project Manager?",
"en": "What is the contact number of Ms. Jena Weber, Regulatory Project Manager?",
"es": "¿Cuál es el número de contacto de la Sra. Jena Weber, Directora del Proyecto Regulador?",
"fr": "Quel est le numéro de contact de Mme Jena Weber, gestionnaire de projet de réglementation?",
"it": "Qual è il numero di contatto della Sig.ra Jena Weber, Responsabile del Progetto Regolatore?"
} | [
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train_396 | null | {
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"en": "What is the full form of ODE?",
"es": "¿Cuál es la forma completa de la ODE?",
"fr": "Quelle est la forme complète de l'ODE?",
"it": "Qual è la forma completa di ODE?"
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train_398 | null | {
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"es": "¿Cuál es la unidad mencionada en la carta?",
"fr": "Quelle est l'unité mentionnée dans la lettre?",
"it": "che cos'è l'unità menzionata nella lettera?"
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train_401 | null | {
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train_403 | null | {
"de": "von wessen Schreibtisch ist dieser Brief geschrieben?",
"en": "from whose desk this letter is written ?",
"es": "¿De quién está escrita esta carta?",
"fr": "de quel bureau cette lettre est-elle écrite?",
"it": "da quale scrivania questa lettera è scritta?"
} | [
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"match_score": 1,
"matched_text": "Timothy J. Gumbleton",
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} | {"gt_parses": [{"question" : "from whose desk this letter is written ?", "answer" : "Timothy J. Gumbleton"}, {"question" : "from whose desk this letter is written ?", "answer" : "timothy J Gumbleton"}]} |
train_404 | null | {
"de": "Wessen Kopie ist beigefügt?",
"en": "Whose letter's copy is attached?",
"es": "¿La copia de la carta de quién está adjunta?",
"fr": "La copie de la lettre de qui est jointe?",
"it": "A chi e' allegata la copia della lettera?"
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"match_score": 0.9166666736111105,
"matched_text": "Do. Mitchell",
"start": 218,
"text": "DR. Mitchell"
} | {"gt_parses": [{"question" : "Whose letter's copy is attached?", "answer" : "DR. Mitchell"}, {"question" : "Whose letter's copy is attached?", "answer" : "Dr. Mitchell"}]} |
train_405 | null | {
"de": "Wie lautet das erwähnte Datum?",
"en": "what is the date mentioned ?",
"es": "¿Cuál es la fecha mencionada?",
"fr": "Quelle est la date mentionnée?",
"it": "Qual è la data indicata?"
} | [
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"february 6 , 1996"
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"match_score": 1,
"matched_text": "February 6, 1996",
"start": 65,
"text": "February 6, 1996"
} | {"gt_parses": [{"question" : "what is the date mentioned ?", "answer" : "February 6, 1996"}, {"question" : "what is the date mentioned ?", "answer" : "february 6 , 1996"}]} |
train_406 | null | {
"de": "an wen dieser Brief geschrieben wird?",
"en": "to whom this letter is written ?",
"es": "¿A quién está escrita esta carta?",
"fr": "à qui cette lettre est-elle écrite?",
"it": "a chi è scritta questa lettera?"
} | [
"Dr. K. KItazawa",
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train_408 | null | {
"de": "Mit welchem Labor ist T. Suzuki verbunden?",
"en": "Which laboratory is T. Suzuki associated with ?",
"es": "¿Con qué laboratorio está asociado T. Suzuki?",
"fr": "Quel laboratoire est associé à T. Suzuki?",
"it": "Quale laboratorio è associato a T. Suzuki?"
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"de": "Wie heißt die Branche hier?",
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"matched_text": "Takeda Chemical Industries, LTD.",
"start": 853,
"text": "Takeda chemical industries, LTD ."
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train_411 | null | {
"de": "an wen dieser Brief geschrieben wird?",
"en": "to whom this letter is written ?",
"es": "¿A quién está escrita esta carta?",
"fr": "à qui cette lettre est-elle écrite?",
"it": "a chi è scritta questa lettera?"
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"de": "Wer hat diesen Brief geschickt?",
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"fr": "Qui a envoyé cette lettre?",
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"fr": "Qu'est-ce que Ref: code mentionné?",
"it": "che cosa è Ref: codice menzionato?"
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train_416 | null | {
"de": "Wie lautet das im Dokument genannte Datum?",
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"es": "¿Cuál es la fecha mencionada en el documento?",
"fr": "Quelle est la date mentionnée dans le document?",
"it": "Qual è la data indicata nel documento?"
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"match_score": 1,
"matched_text": "Monday, 12 and Tuesday, 13 August 2002",
"start": 181,
"text": "Monday, 12 and Tuesday, 13 August 2002"
} | {"gt_parses": [{"question" : "What is the date mentioned in the document?", "answer" : "Monday, 12 and Tuesday, 13 August 2002"}]} |
train_417 | null | {
"de": "Wie lautet die Faxnummer, die oben im Brief erwähnt wird?",
"en": "what is the fax number mentioned in the letter at the top?",
"es": "¿Cuál es el número de fax mencionado en la carta en la parte superior?",
"fr": "Quel est le numéro de télécopieur mentionné dans la lettre en haut?",
"it": "Qual è il numero di fax menzionato nella lettera in alto?"
} | [
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] | {
"match_score": 1,
"matched_text": "06 6204 2244",
"start": 17,
"text": "06 6204 2244"
} | {"gt_parses": [{"question" : "what is the fax number mentioned in the letter at the top?", "answer" : "06 6204 2244"}]} |
train_418 | null | {
"de": "was ist das Datum und die Zeit erwähnt?",
"en": "what is the date and time mentioned ?",
"es": "¿Cuál es la fecha y hora mencionadas?",
"fr": "Quelle est la date et l'heure mentionnées?",
"it": "Qual è la data e l'ora di cui si parla?"
} | [
"10/27/93 09:36:07"
] | [
"From:",
"PLK",
"RCC1",
"Date",
"and",
"time",
"10/27/93",
"09",
":",
"36:07",
"To:",
"PJDANIEL-",
"-",
"PW17",
"PO",
"PETER",
"J.",
"DANIELS",
"CC:",
"RJWELTER-",
"-",
"PW17",
"PO",
"RICHARD",
"J.",
"WELTER",
"LTWELCH",
"--RCC1",
"LAWRENCE",
"T",
"WELCH",
"From:",
"plruppel",
"subject:",
"Pioglitazone",
"statement",
"Actually,",
"this",
"statement",
"reflects",
"pretty",
"accurately",
"the",
"stand",
"that",
"Jim",
"Moe",
"and",
"Larry",
"Olanoff",
"presented",
"to",
"Takeda",
"in",
"Osaka.",
"There",
"are",
"preclinical",
"issues",
"and",
"the",
"amount",
"of",
"preclinical",
"work",
"that",
"would",
"be",
"needed",
"to",
"address",
"these",
"issues",
"and",
"the",
"modest",
"clinical",
"efficacy",
"that",
"has",
"been",
"seen",
"do",
"not",
"justify",
"development",
"in",
"accordance",
"with",
"Upjohn's",
"business",
"needs.",
"Larry",
"does",
"not",
"feel",
"that",
"there",
"is",
"a",
"need",
"for",
"an",
"\"Upjohn",
"statement\".",
"Please",
"let",
"me",
"know",
"if",
"you",
"want",
"to",
"discuss",
"this",
"further.",
"Patty",
"***",
"Forwarding",
"note",
"from",
"PJDANIEL--PW17PO",
"10/26/93",
"15:44",
"*",
"*",
"*",
"From:",
"PJDANIEL",
"To:",
"PLRUPPEL--RCC1",
"RUPPEL,",
"PATRICIA",
"CC",
":",
"PJDANIEL",
"RJWELTER",
"LTWELCH",
"-",
"-RCC1",
"WELCH,",
"LAWRENCE",
"Subject:",
"Pioglitazone",
"statement",
"Patty,",
"thanks",
"for",
"the",
"Takeda",
"letter.",
"Some",
"of",
"my",
"colleagues",
"are",
"concerned",
"about",
"the",
"lack",
"of",
"frankness",
"(and",
"honesty?)",
"of",
"the",
"Takeda",
"statement.",
"We",
"realise",
"we",
"are",
"hemmed",
"in",
"by",
"a",
"confidentiality",
"clause,",
"but",
"does",
"this",
"have",
"the",
"endorsement",
"of",
"our",
"senior",
"management",
".",
"Regards,",
"Peter.",
"tile",
"-",
"Takedy",
"blogde",
"fizone",
"license",
"ast",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
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"match_score": 0.894736847645429,
"matched_text": "10/27/93 09 : 36:07",
"start": 29,
"text": "10/27/93 09:36:07"
} | {"gt_parses": [{"question" : "what is the date and time mentioned ?", "answer" : "10/27/93 09:36:07"}]} |
train_419 | null | {
"de": "Was wird in dem Thema erwähnt?",
"en": "what is mentioned in the subject ?",
"es": "¿Qué se menciona en el tema?",
"fr": "qu'est-ce qui est mentionné dans le sujet?",
"it": "che cosa viene menzionato nell'argomento?"
} | [
"Pioglitazone statement",
"pioglitazone statement"
] | [
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"Patty",
"***",
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".",
"Regards,",
"Peter.",
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"-",
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"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
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] | {
"match_score": 1,
"matched_text": "Pioglitazone statement",
"start": 188,
"text": "Pioglitazone statement"
} | {"gt_parses": [{"question" : "what is mentioned in the subject ?", "answer" : "Pioglitazone statement"}, {"question" : "what is mentioned in the subject ?", "answer" : "pioglitazone statement"}]} |
train_420 | null | {
"de": "An wen wurde diese E-Mail geschickt?",
"en": "To whom this email was send?",
"es": "¿A quién se envió este correo electrónico?",
"fr": "À qui ce courriel a-t-il été envoyé?",
"it": "A chi è stata inviata questa email?"
} | [
"PETER J. DANIELS",
"PJ DANIEL--PW17PO PETER J. DANIELS"
] | [
"From:",
"PLK",
"RCC1",
"Date",
"and",
"time",
"10/27/93",
"09",
":",
"36:07",
"To:",
"PJDANIEL-",
"-",
"PW17",
"PO",
"PETER",
"J.",
"DANIELS",
"CC:",
"RJWELTER-",
"-",
"PW17",
"PO",
"RICHARD",
"J.",
"WELTER",
"LTWELCH",
"--RCC1",
"LAWRENCE",
"T",
"WELCH",
"From:",
"plruppel",
"subject:",
"Pioglitazone",
"statement",
"Actually,",
"this",
"statement",
"reflects",
"pretty",
"accurately",
"the",
"stand",
"that",
"Jim",
"Moe",
"and",
"Larry",
"Olanoff",
"presented",
"to",
"Takeda",
"in",
"Osaka.",
"There",
"are",
"preclinical",
"issues",
"and",
"the",
"amount",
"of",
"preclinical",
"work",
"that",
"would",
"be",
"needed",
"to",
"address",
"these",
"issues",
"and",
"the",
"modest",
"clinical",
"efficacy",
"that",
"has",
"been",
"seen",
"do",
"not",
"justify",
"development",
"in",
"accordance",
"with",
"Upjohn's",
"business",
"needs.",
"Larry",
"does",
"not",
"feel",
"that",
"there",
"is",
"a",
"need",
"for",
"an",
"\"Upjohn",
"statement\".",
"Please",
"let",
"me",
"know",
"if",
"you",
"want",
"to",
"discuss",
"this",
"further.",
"Patty",
"***",
"Forwarding",
"note",
"from",
"PJDANIEL--PW17PO",
"10/26/93",
"15:44",
"*",
"*",
"*",
"From:",
"PJDANIEL",
"To:",
"PLRUPPEL--RCC1",
"RUPPEL,",
"PATRICIA",
"CC",
":",
"PJDANIEL",
"RJWELTER",
"LTWELCH",
"-",
"-RCC1",
"WELCH,",
"LAWRENCE",
"Subject:",
"Pioglitazone",
"statement",
"Patty,",
"thanks",
"for",
"the",
"Takeda",
"letter.",
"Some",
"of",
"my",
"colleagues",
"are",
"concerned",
"about",
"the",
"lack",
"of",
"frankness",
"(and",
"honesty?)",
"of",
"the",
"Takeda",
"statement.",
"We",
"realise",
"we",
"are",
"hemmed",
"in",
"by",
"a",
"confidentiality",
"clause,",
"but",
"does",
"this",
"have",
"the",
"endorsement",
"of",
"our",
"senior",
"management",
".",
"Regards,",
"Peter.",
"tile",
"-",
"Takedy",
"blogde",
"fizone",
"license",
"ast",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
] | [
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] | {
"match_score": 1,
"matched_text": "PETER J. DANIELS",
"start": 73,
"text": "PETER J. DANIELS"
} | {"gt_parses": [{"question" : "To whom this email was send?", "answer" : "PETER J. DANIELS"}, {"question" : "To whom this email was send?", "answer" : "PJ DANIEL--PW17PO PETER J. DANIELS"}]} |
train_421 | null | {
"de": "Was ist das Datum, das in der Weiterleitungsnotiz erwähnt wird?",
"en": "what is the date mentioned in the forwarding note ?",
"es": "¿Cuál es la fecha mencionada en la nota de reenvío?",
"fr": "Quelle est la date mentionnée dans la note d'envoi?",
"it": "Qual è la data indicata nella nota di trasmissione?"
} | [
"10/26/93",
"10/26/93 15:44"
] | [
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"an",
"\"Upjohn",
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"Please",
"let",
"me",
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"you",
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"to",
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"this",
"further.",
"Patty",
"***",
"Forwarding",
"note",
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"PJDANIEL--PW17PO",
"10/26/93",
"15:44",
"*",
"*",
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"PATRICIA",
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"letter.",
"Some",
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"my",
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"but",
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"Regards,",
"Peter.",
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"-",
"SUBJECT",
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"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
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] | {
"match_score": 1,
"matched_text": "10/26/93",
"start": 738,
"text": "10/26/93"
} | {"gt_parses": [{"question" : "what is the date mentioned in the forwarding note ?", "answer" : "10/26/93"}, {"question" : "what is the date mentioned in the forwarding note ?", "answer" : "10/26/93 15:44"}]} |
train_422 | null | {
"de": "Was ist die Zeit, die in der Weiterleitungsnotiz erwähnt wird?",
"en": "what is the time mentioned in the forwarding note ?",
"es": "¿Cuál es el tiempo mencionado en la nota de reenvío?",
"fr": "Quelle est la période mentionnée dans la note de renvoi?",
"it": "Qual è l'ora indicata nella nota di trasmissione?"
} | [
"15:44"
] | [
"From:",
"PLK",
"RCC1",
"Date",
"and",
"time",
"10/27/93",
"09",
":",
"36:07",
"To:",
"PJDANIEL-",
"-",
"PW17",
"PO",
"PETER",
"J.",
"DANIELS",
"CC:",
"RJWELTER-",
"-",
"PW17",
"PO",
"RICHARD",
"J.",
"WELTER",
"LTWELCH",
"--RCC1",
"LAWRENCE",
"T",
"WELCH",
"From:",
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"subject:",
"Pioglitazone",
"statement",
"Actually,",
"this",
"statement",
"reflects",
"pretty",
"accurately",
"the",
"stand",
"that",
"Jim",
"Moe",
"and",
"Larry",
"Olanoff",
"presented",
"to",
"Takeda",
"in",
"Osaka.",
"There",
"are",
"preclinical",
"issues",
"and",
"the",
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"preclinical",
"work",
"that",
"would",
"be",
"needed",
"to",
"address",
"these",
"issues",
"and",
"the",
"modest",
"clinical",
"efficacy",
"that",
"has",
"been",
"seen",
"do",
"not",
"justify",
"development",
"in",
"accordance",
"with",
"Upjohn's",
"business",
"needs.",
"Larry",
"does",
"not",
"feel",
"that",
"there",
"is",
"a",
"need",
"for",
"an",
"\"Upjohn",
"statement\".",
"Please",
"let",
"me",
"know",
"if",
"you",
"want",
"to",
"discuss",
"this",
"further.",
"Patty",
"***",
"Forwarding",
"note",
"from",
"PJDANIEL--PW17PO",
"10/26/93",
"15:44",
"*",
"*",
"*",
"From:",
"PJDANIEL",
"To:",
"PLRUPPEL--RCC1",
"RUPPEL,",
"PATRICIA",
"CC",
":",
"PJDANIEL",
"RJWELTER",
"LTWELCH",
"-",
"-RCC1",
"WELCH,",
"LAWRENCE",
"Subject:",
"Pioglitazone",
"statement",
"Patty,",
"thanks",
"for",
"the",
"Takeda",
"letter.",
"Some",
"of",
"my",
"colleagues",
"are",
"concerned",
"about",
"the",
"lack",
"of",
"frankness",
"(and",
"honesty?)",
"of",
"the",
"Takeda",
"statement.",
"We",
"realise",
"we",
"are",
"hemmed",
"in",
"by",
"a",
"confidentiality",
"clause,",
"but",
"does",
"this",
"have",
"the",
"endorsement",
"of",
"our",
"senior",
"management",
".",
"Regards,",
"Peter.",
"tile",
"-",
"Takedy",
"blogde",
"fizone",
"license",
"ast",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
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"match_score": 1,
"matched_text": "15:44",
"start": 747,
"text": "15:44"
} | {"gt_parses": [{"question" : "what is the time mentioned in the forwarding note ?", "answer" : "15:44"}]} |
train_423 | null | {
"de": "Wem wurde diese E-Mail verwehrt?",
"en": "To whom this email was forwaded?",
"es": "¿A quién se perdonó este correo electrónico?",
"fr": "À qui cet e-mail a-t-il été annulé?",
"it": "A chi è stata forwaded questa email?"
} | [
"RUPPEL, PATRICIA",
"PLRUPPEL--RCC1 RUPPEL, PATRICIA"
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"is",
"a",
"need",
"for",
"an",
"\"Upjohn",
"statement\".",
"Please",
"let",
"me",
"know",
"if",
"you",
"want",
"to",
"discuss",
"this",
"further.",
"Patty",
"***",
"Forwarding",
"note",
"from",
"PJDANIEL--PW17PO",
"10/26/93",
"15:44",
"*",
"*",
"*",
"From:",
"PJDANIEL",
"To:",
"PLRUPPEL--RCC1",
"RUPPEL,",
"PATRICIA",
"CC",
":",
"PJDANIEL",
"RJWELTER",
"LTWELCH",
"-",
"-RCC1",
"WELCH,",
"LAWRENCE",
"Subject:",
"Pioglitazone",
"statement",
"Patty,",
"thanks",
"for",
"the",
"Takeda",
"letter.",
"Some",
"of",
"my",
"colleagues",
"are",
"concerned",
"about",
"the",
"lack",
"of",
"frankness",
"(and",
"honesty?)",
"of",
"the",
"Takeda",
"statement.",
"We",
"realise",
"we",
"are",
"hemmed",
"in",
"by",
"a",
"confidentiality",
"clause,",
"but",
"does",
"this",
"have",
"the",
"endorsement",
"of",
"our",
"senior",
"management",
".",
"Regards,",
"Peter.",
"tile",
"-",
"Takedy",
"blogde",
"fizone",
"license",
"ast",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065604",
"Source:",
"https://www.indupbydemoodonts.ucsf.edu/docs/sljf0226"
] | [
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] | {
"match_score": 1,
"matched_text": "RUPPEL, PATRICIA",
"start": 793,
"text": "RUPPEL, PATRICIA"
} | {"gt_parses": [{"question" : "To whom this email was forwaded?", "answer" : "RUPPEL, PATRICIA"}, {"question" : "To whom this email was forwaded?", "answer" : "PLRUPPEL--RCC1 RUPPEL, PATRICIA"}]} |
train_424 | null | {
"de": "wie ist der Name des Unternehmens",
"en": "what is the name of the company",
"es": "cuál es el nombre de la empresa",
"fr": "quel est le nom de l'entreprise",
"it": "qual è il nome dell'azienda"
} | [
"THE UPJOHN COMPANY"
] | [
"TAKEDA",
"Aat",
"THE",
"UPJOHN",
"COMPANY",
"KALAMAZOO,",
"MICHIGAN",
"49001-0199.",
"U.S.A.",
"TELEPHONE:",
"(616)",
"323-4000.",
"J.",
"R.",
"MITCHELL,",
"M.D.",
"A.D.",
"Vice",
"Chairman",
"of",
"the",
"Board",
"TELEPHONE.",
"(614)",
"385-7053",
"(816)",
"385-5291",
"September",
"21,",
"1993",
"Tai",
"Matsuzawa,",
"Ph.D.",
"Managing",
"Director",
"Vice",
"President,",
"Pharmaceutical",
"Group",
"Takeda",
"Chemical",
"Industries,",
"Lid,",
"1-1,",
"Doshomachi",
"4-Chome",
"Chuo-Ku,",
"Osaka",
"541",
"Japan",
"Dear",
"Doctor",
"Matsuzawa:",
"As",
"you",
"know,",
"Upjohn",
"has",
"committed",
"to",
"notify",
"Takeda",
"by",
"October",
"1,",
"1993,",
"of",
"our",
"intentions",
"regarding",
"further",
"clinical",
"development",
"of",
"pioglitazone.",
"On",
"September",
"20",
"our",
"Pharmaceutical",
"Executive",
"Council,",
"Upjohn's",
"highest",
"scientific",
"decision-making",
"body,",
"carefully",
"reviewed",
"the",
"results",
"of",
"the",
"toxicology",
"and",
"clinical",
"studies.",
"The",
"decision",
"of",
"the",
"Council",
"was",
"that",
"Upjohn",
"will",
"not",
"go",
"forward",
"with",
"pioglitazone",
"in",
"the",
"clinic.",
"The",
"Council",
"decided",
"that",
"further",
"clinical",
"development",
"of",
"pioglitazone",
"could",
"not",
"be",
"justified",
"based",
"on",
"their",
"concern",
"regarding",
"pioglitazone's",
"margin",
"of",
"safety.",
"As",
"a",
"consequence",
"of",
"this",
"decision,",
"Upjohn",
"also",
"must",
"decline",
"participation",
"with",
"Takeda",
"on",
"the",
"proposed",
"pioglitazone",
"study",
"in",
"Canada.",
"It",
"is",
"with",
"deep",
"regret",
"that",
"I",
"convey",
"this",
"message.",
"As",
"you",
"know",
"Upjohn",
"and",
"Takeda",
"enjoy",
"a",
"strong",
"and",
"beneficial",
"relationship",
"based",
"on",
"mutual",
"respect.",
"It",
"is",
"a",
"great",
"disappointment",
"to",
"us",
"that",
"we",
"will",
"not",
"have",
"the",
"opportunity",
"of",
"further",
"interactions",
"and",
"collaboration",
"with",
"Takeda",
"on",
"this",
"project.",
"Hopefully,",
"we",
"will",
"find",
"other",
"opportunities",
"for",
"collaboration",
"in",
"the",
"future.",
"I",
"have",
"instructed",
"my",
"staff",
"to",
"work",
"closely",
"with",
"Takeda",
"personnel",
"in",
"regards",
"to",
"the",
"release",
"of",
"any",
"information,",
"data,",
"FDA",
"notifications,",
"and",
"other",
"issues",
"to",
"ensure",
"Takeda's",
"interests",
"and",
"wishes",
"are",
"followed.",
"With",
"best",
"personal",
"regards,",
"Sincerely,",
"President,",
"Upjohn",
"Laboratories",
"Worldwide",
"Research,",
"Development,",
"&",
"Medical",
"Affairs",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065603",
"Source:",
"https://www.indup606-oooo2ts.ucsf.edu/docs/zsjf0226"
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] | {
"match_score": 1,
"matched_text": "THE UPJOHN COMPANY",
"start": 11,
"text": "THE UPJOHN COMPANY"
} | {"gt_parses": [{"question" : "what is the name of the company", "answer" : "THE UPJOHN COMPANY"}]} |
train_425 | null | {
"de": "Was ist das erwähnte Datum und Jahr?",
"en": "what is the date and year mentioned ?",
"es": "¿Cuál es la fecha y el año mencionados?",
"fr": "Quelle est la date et l'année mentionnées?",
"it": "Qual è la data e l'anno menzionati?"
} | [
"September 21, 1993",
"september 21 , 1993"
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"KALAMAZOO,",
"MICHIGAN",
"49001-0199.",
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"J.",
"R.",
"MITCHELL,",
"M.D.",
"A.D.",
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"convey",
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"and",
"Takeda",
"enjoy",
"a",
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"have",
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"Sincerely,",
"President,",
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"Laboratories",
"Worldwide",
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"&",
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"-",
"SUBJECT",
"TO",
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"ORDER",
"UPJ-0065603",
"Source:",
"https://www.indup606-oooo2ts.ucsf.edu/docs/zsjf0226"
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] | {
"match_score": 1,
"matched_text": "September 21, 1993",
"start": 190,
"text": "September 21, 1993"
} | {"gt_parses": [{"question" : "what is the date and year mentioned ?", "answer" : "September 21, 1993"}, {"question" : "what is the date and year mentioned ?", "answer" : "september 21 , 1993"}]} |
train_426 | null | {
"de": "Welche Firma wird im Briefkopf erwähnt?",
"en": "Which company is mentioned in the letterhead?",
"es": "¿Qué compañía se menciona en el membrete?",
"fr": "Quelle société est mentionnée dans l'en-tête?",
"it": "Quale azienda è menzionata nella carta intestata?"
} | [
"THE UPJOHN COMPANY"
] | [
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"convey",
"this",
"message.",
"As",
"you",
"know",
"Upjohn",
"and",
"Takeda",
"enjoy",
"a",
"strong",
"and",
"beneficial",
"relationship",
"based",
"on",
"mutual",
"respect.",
"It",
"is",
"a",
"great",
"disappointment",
"to",
"us",
"that",
"we",
"will",
"not",
"have",
"the",
"opportunity",
"of",
"further",
"interactions",
"and",
"collaboration",
"with",
"Takeda",
"on",
"this",
"project.",
"Hopefully,",
"we",
"will",
"find",
"other",
"opportunities",
"for",
"collaboration",
"in",
"the",
"future.",
"I",
"have",
"instructed",
"my",
"staff",
"to",
"work",
"closely",
"with",
"Takeda",
"personnel",
"in",
"regards",
"to",
"the",
"release",
"of",
"any",
"information,",
"data,",
"FDA",
"notifications,",
"and",
"other",
"issues",
"to",
"ensure",
"Takeda's",
"interests",
"and",
"wishes",
"are",
"followed.",
"With",
"best",
"personal",
"regards,",
"Sincerely,",
"President,",
"Upjohn",
"Laboratories",
"Worldwide",
"Research,",
"Development,",
"&",
"Medical",
"Affairs",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065603",
"Source:",
"https://www.indup606-oooo2ts.ucsf.edu/docs/zsjf0226"
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] | {
"match_score": 1,
"matched_text": "THE UPJOHN COMPANY",
"start": 11,
"text": "THE UPJOHN COMPANY"
} | {"gt_parses": [{"question" : "Which company is mentioned in the letterhead?", "answer" : "THE UPJOHN COMPANY"}]} |
train_427 | null | {
"de": "In welchem Land befindet sich die Firma upjohn?",
"en": "in which country the upjohn company is located ?",
"es": "¿En qué país se encuentra la empresa upjohn?",
"fr": "Dans quel pays se trouve la société upjohn?",
"it": "in quale paese si trova la società upjohn?"
} | [
"U.S.A",
"USA"
] | [
"TAKEDA",
"Aat",
"THE",
"UPJOHN",
"COMPANY",
"KALAMAZOO,",
"MICHIGAN",
"49001-0199.",
"U.S.A.",
"TELEPHONE:",
"(616)",
"323-4000.",
"J.",
"R.",
"MITCHELL,",
"M.D.",
"A.D.",
"Vice",
"Chairman",
"of",
"the",
"Board",
"TELEPHONE.",
"(614)",
"385-7053",
"(816)",
"385-5291",
"September",
"21,",
"1993",
"Tai",
"Matsuzawa,",
"Ph.D.",
"Managing",
"Director",
"Vice",
"President,",
"Pharmaceutical",
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"Takeda",
"Chemical",
"Industries,",
"Lid,",
"1-1,",
"Doshomachi",
"4-Chome",
"Chuo-Ku,",
"Osaka",
"541",
"Japan",
"Dear",
"Doctor",
"Matsuzawa:",
"As",
"you",
"know,",
"Upjohn",
"has",
"committed",
"to",
"notify",
"Takeda",
"by",
"October",
"1,",
"1993,",
"of",
"our",
"intentions",
"regarding",
"further",
"clinical",
"development",
"of",
"pioglitazone.",
"On",
"September",
"20",
"our",
"Pharmaceutical",
"Executive",
"Council,",
"Upjohn's",
"highest",
"scientific",
"decision-making",
"body,",
"carefully",
"reviewed",
"the",
"results",
"of",
"the",
"toxicology",
"and",
"clinical",
"studies.",
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"decision",
"of",
"the",
"Council",
"was",
"that",
"Upjohn",
"will",
"not",
"go",
"forward",
"with",
"pioglitazone",
"in",
"the",
"clinic.",
"The",
"Council",
"decided",
"that",
"further",
"clinical",
"development",
"of",
"pioglitazone",
"could",
"not",
"be",
"justified",
"based",
"on",
"their",
"concern",
"regarding",
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"margin",
"of",
"safety.",
"As",
"a",
"consequence",
"of",
"this",
"decision,",
"Upjohn",
"also",
"must",
"decline",
"participation",
"with",
"Takeda",
"on",
"the",
"proposed",
"pioglitazone",
"study",
"in",
"Canada.",
"It",
"is",
"with",
"deep",
"regret",
"that",
"I",
"convey",
"this",
"message.",
"As",
"you",
"know",
"Upjohn",
"and",
"Takeda",
"enjoy",
"a",
"strong",
"and",
"beneficial",
"relationship",
"based",
"on",
"mutual",
"respect.",
"It",
"is",
"a",
"great",
"disappointment",
"to",
"us",
"that",
"we",
"will",
"not",
"have",
"the",
"opportunity",
"of",
"further",
"interactions",
"and",
"collaboration",
"with",
"Takeda",
"on",
"this",
"project.",
"Hopefully,",
"we",
"will",
"find",
"other",
"opportunities",
"for",
"collaboration",
"in",
"the",
"future.",
"I",
"have",
"instructed",
"my",
"staff",
"to",
"work",
"closely",
"with",
"Takeda",
"personnel",
"in",
"regards",
"to",
"the",
"release",
"of",
"any",
"information,",
"data,",
"FDA",
"notifications,",
"and",
"other",
"issues",
"to",
"ensure",
"Takeda's",
"interests",
"and",
"wishes",
"are",
"followed.",
"With",
"best",
"personal",
"regards,",
"Sincerely,",
"President,",
"Upjohn",
"Laboratories",
"Worldwide",
"Research,",
"Development,",
"&",
"Medical",
"Affairs",
"CONFIDENTIAL",
"-",
"SUBJECT",
"TO",
"PROTECTIVE",
"ORDER",
"UPJ-0065603",
"Source:",
"https://www.indup606-oooo2ts.ucsf.edu/docs/zsjf0226"
] | [
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] | {
"match_score": 1,
"matched_text": "U.S.A",
"start": 62,
"text": "U.S.A"
} | {"gt_parses": [{"question" : "in which country the upjohn company is located ?", "answer" : "U.S.A"}, {"question" : "in which country the upjohn company is located ?", "answer" : "USA"}]} |
train_428 | null | {
"de": "Was ist das Fax erwähnt?",
"en": "what is the fax mentioned ?",
"es": "¿Cuál es el fax mencionado?",
"fr": "Qu'est-ce que le fax mentionné?",
"it": "Qual è il fax menzionato?"
} | [
"06 6204 2244"
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"match_score": 1,
"matched_text": "06 6204 2244",
"start": 17,
"text": "06 6204 2244"
} | {"gt_parses": [{"question" : "what is the fax mentioned ?", "answer" : "06 6204 2244"}]} |
train_429 | null | {
"de": "was ist Jahr Datum und Zeit erwähnt?",
"en": "what is year date and time mentioned?",
"es": "¿Qué se menciona fecha y hora del año?",
"fr": "Quelle est la date et l'heure de l'année mentionnées?",
"it": "che cos'è la data e l'ora dell'anno?"
} | [
"2002 08/08 21:49"
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"match_score": 1,
"matched_text": "2002 08/08 21:49",
"start": 30,
"text": "2002 08/08 21:49"
} | {"gt_parses": [{"question" : "what is year date and time mentioned?", "answer" : "2002 08/08 21:49"}]} |
train_430 | null | {
"de": "Wie lautet der Name der Abteilung?",
"en": "what is the name of the division ?",
"es": "¿Cuál es el nombre de la división?",
"fr": "Quel est le nom de la division?",
"it": "Qual è il nome della divisione?"
} | [
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] | {
"match_score": 1,
"matched_text": "TAKEDA DEVELOP DIVISION",
"start": 64,
"text": "TAKEDA DEVELOP DIVISION"
} | {"gt_parses": [{"question" : "what is the name of the division ?", "answer" : "TAKEDA DEVELOP DIVISION"}, {"question" : "what is the name of the division ?", "answer" : "Takeda Develop division"}]} |
train_431 | null | {
"de": "An wen können sie sich direkt wenden, um die Einzelheiten der \"Promotionsstudie\" bekannt zu geben?",
"en": "to whom they can ask directly to disclose the details of \"promotion study\"?",
"es": "¿a quién pueden pedir directamente que revele los detalles del \"estudio de promoción\"?",
"fr": "à qui ils peuvent demander directement de divulguer les détails de \"l'étude de promotion\"?",
"it": "a chi possono chiedere direttamente di divulgare i dettagli dello \"studio di promozione\"?"
} | [
"FDA"
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] | {
"match_score": 1,
"matched_text": "FDA",
"start": 331,
"text": "FDA"
} | {"gt_parses": [{"question" : "to whom they can ask directly to disclose the details of \"promotion study\"?", "answer" : "FDA"}]} |
train_432 | null | {
"de": "Wie lautet das im Schreiben genannte Datum?",
"en": "what is the date mentioned in the letter",
"es": "¿Cuál es la fecha mencionada en la carta",
"fr": "quelle est la date mentionnée dans la lettre",
"it": "qual è la data indicata nella lettera"
} | [
"8 January 2003",
"8 january 2003"
] | [
"8",
"January",
"2003",
"To:",
"MPDRAP",
"I",
"Leader",
"cc:",
"CEOs",
"and",
"General",
"Managers",
"of",
"Pharmaceutical",
"Units",
"My",
"Concerns",
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"sNDA",
"for",
"Actos",
"45mg",
"in",
"the",
"USA",
"(Reconfirmation)",
"Pharmaceutical",
"International",
"Division",
"Y.",
"Narai",
"I",
"express",
"my",
"opinion",
"about",
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"at",
"MPDRAP",
"Committee",
"Meeting",
"where",
"it",
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"as",
"well",
"as",
"the",
"safety",
"update",
"based",
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"As",
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"know,",
"Actos",
"is",
"the",
"essential",
"product",
"for",
"IPNA",
"and",
"is",
"vital",
"to",
"the",
"survival",
"of",
"TPNA.",
"If",
"unfavorable",
"revisions",
"in",
"the",
"Actos",
"labeling",
"are",
"made,",
"it",
"invites",
"the",
"serious",
"risk",
"to",
"Actos",
"in",
"the",
"US.",
"TPNA",
"is",
"now",
"under",
"attack",
"from",
"GSK,",
"especially",
"by",
"Avandamet",
"and",
"is",
"eager",
"to",
"maintain",
"their",
"market",
"share.",
"In",
"addition",
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"this",
"attack,",
"if",
"the",
"indications",
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"Actos",
"are",
"reduced,",
"TPNA",
"is",
"pushed",
"into",
"critical",
"situation.",
"This",
"issue",
"seriously",
"damages",
"not",
"only",
"US",
"market",
"but",
"also",
"Takeda's",
"global",
"strategy.",
"Therefore,",
"HQ",
"should",
"be",
"extremely",
"cautious",
"about",
"the",
"issues",
"related",
"to",
"Actos.",
"If",
"this",
"sNDA",
"raises",
"the",
"argument",
"for",
"the",
"indications",
"of",
"Actos,",
"for",
"example,",
"reductions",
"in",
"the",
"indications,",
"the",
"issues",
"will",
"come",
"to",
"a",
"critical",
"path",
"like",
"as",
"I",
"mentioned.",
"So",
"we",
"should",
"go",
"into",
"action",
"on",
"condition",
"that",
"there",
"is",
"no",
"such",
"risk.",
"Combination",
"therapy",
"in",
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"US",
"market",
"accounts",
"for",
"64%",
"of",
"total",
"Actos",
"sales.",
"(29%",
"in",
"combination",
"with",
"SU,",
"27%",
"Metformin",
"and",
"8%",
"Insulin)",
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"the",
"possibility",
"of",
"the",
"risk",
"of",
"labeling",
"revision,",
"International",
"Division",
"entrusts",
"Development",
"Division",
"with",
"final",
"decision.",
"However,",
"just",
"to",
"be",
"sure,",
"I",
"would",
"like",
"to",
"reconfirm",
"that",
"this",
"sNDA",
"dose",
"not",
"lead",
"to",
"a",
"serious",
"situation.",
"I",
"heard",
"that",
"TPNA",
"R&D",
"suggested",
"to",
"HQ",
"and",
"is",
"getting",
"ready",
"for",
"sNDA",
"for",
"the",
"45mg",
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"However,",
"HQ",
"should",
"carefully",
"judge",
"whether",
"this",
"sNDA",
"should",
"be",
"submitted",
"to",
"the",
"FDA",
"or",
"not.",
"I",
"think",
"that",
"sNDA",
"for",
"efficacy",
"should",
"be",
"submitted",
"only",
"when",
"there",
"is",
"no",
"risk",
"that",
"this",
"sND",
"A",
"damages",
"the",
"current",
"labeling.",
"According",
"to",
"the",
"results",
"of",
"PNFP-343,",
"combination",
"with",
"insulin,",
"edema",
"was",
"observed",
"more",
"often",
"than",
"Avandia,",
"which",
"dose",
"not",
"have",
"the",
"indication",
"for",
"combination",
"with",
"insulin",
"and",
"CHF",
"in",
"this",
"study",
"seems",
"to",
"be",
"dose",
"related.",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-THOMCL-00005583",
"Produced",
"in",
"MDL",
"on",
"09/14/12",
"Source:",
"https://www.indupt2290-coots.ucsf.edu/docs/syjf0226"
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] | {
"match_score": 1,
"matched_text": "8 January 2003",
"start": 0,
"text": "8 January 2003"
} | {"gt_parses": [{"question" : "what is the date mentioned in the letter", "answer" : "8 January 2003"}, {"question" : "what is the date mentioned in the letter", "answer" : "8 january 2003"}]} |
train_433 | null | {
"de": "An wen ist dieser Brief gerichtet?",
"en": "To whom this letter is addressed?",
"es": "¿A quién se dirige esta carta?",
"fr": "À qui s'adresse cette lettre?",
"it": "A chi è indirizzata questa lettera?"
} | [
"MPDRAP I Leader"
] | [
"8",
"January",
"2003",
"To:",
"MPDRAP",
"I",
"Leader",
"cc:",
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"Managers",
"of",
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"Units",
"My",
"Concerns",
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"for",
"Actos",
"45mg",
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"(Reconfirmation)",
"Pharmaceutical",
"International",
"Division",
"Y.",
"Narai",
"I",
"express",
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"Committee",
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"As",
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"product",
"for",
"IPNA",
"and",
"is",
"vital",
"to",
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"If",
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"it",
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"especially",
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"if",
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"only",
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"edema",
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"which",
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"CHF",
"in",
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"seems",
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"be",
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"-",
"Subject",
"to",
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"Order",
"TAK-THOMCL-00005583",
"Produced",
"in",
"MDL",
"on",
"09/14/12",
"Source:",
"https://www.indupt2290-coots.ucsf.edu/docs/syjf0226"
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train_434 | null | {
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"the",
"45mg",
"combination",
"indications",
"would",
"be",
"submitted,",
"as",
"well",
"as",
"the",
"safety",
"update",
"based",
"on",
"the",
"commitment",
"studies.",
"As",
"you",
"know,",
"Actos",
"is",
"the",
"essential",
"product",
"for",
"IPNA",
"and",
"is",
"vital",
"to",
"the",
"survival",
"of",
"TPNA.",
"If",
"unfavorable",
"revisions",
"in",
"the",
"Actos",
"labeling",
"are",
"made,",
"it",
"invites",
"the",
"serious",
"risk",
"to",
"Actos",
"in",
"the",
"US.",
"TPNA",
"is",
"now",
"under",
"attack",
"from",
"GSK,",
"especially",
"by",
"Avandamet",
"and",
"is",
"eager",
"to",
"maintain",
"their",
"market",
"share.",
"In",
"addition",
"to",
"this",
"attack,",
"if",
"the",
"indications",
"of",
"Actos",
"are",
"reduced,",
"TPNA",
"is",
"pushed",
"into",
"critical",
"situation.",
"This",
"issue",
"seriously",
"damages",
"not",
"only",
"US",
"market",
"but",
"also",
"Takeda's",
"global",
"strategy.",
"Therefore,",
"HQ",
"should",
"be",
"extremely",
"cautious",
"about",
"the",
"issues",
"related",
"to",
"Actos.",
"If",
"this",
"sNDA",
"raises",
"the",
"argument",
"for",
"the",
"indications",
"of",
"Actos,",
"for",
"example,",
"reductions",
"in",
"the",
"indications,",
"the",
"issues",
"will",
"come",
"to",
"a",
"critical",
"path",
"like",
"as",
"I",
"mentioned.",
"So",
"we",
"should",
"go",
"into",
"action",
"on",
"condition",
"that",
"there",
"is",
"no",
"such",
"risk.",
"Combination",
"therapy",
"in",
"the",
"US",
"market",
"accounts",
"for",
"64%",
"of",
"total",
"Actos",
"sales.",
"(29%",
"in",
"combination",
"with",
"SU,",
"27%",
"Metformin",
"and",
"8%",
"Insulin)",
"Regarding",
"the",
"possibility",
"of",
"the",
"risk",
"of",
"labeling",
"revision,",
"International",
"Division",
"entrusts",
"Development",
"Division",
"with",
"final",
"decision.",
"However,",
"just",
"to",
"be",
"sure,",
"I",
"would",
"like",
"to",
"reconfirm",
"that",
"this",
"sNDA",
"dose",
"not",
"lead",
"to",
"a",
"serious",
"situation.",
"I",
"heard",
"that",
"TPNA",
"R&D",
"suggested",
"to",
"HQ",
"and",
"is",
"getting",
"ready",
"for",
"sNDA",
"for",
"the",
"45mg",
"combination",
"indications.",
"However,",
"HQ",
"should",
"carefully",
"judge",
"whether",
"this",
"sNDA",
"should",
"be",
"submitted",
"to",
"the",
"FDA",
"or",
"not.",
"I",
"think",
"that",
"sNDA",
"for",
"efficacy",
"should",
"be",
"submitted",
"only",
"when",
"there",
"is",
"no",
"risk",
"that",
"this",
"sND",
"A",
"damages",
"the",
"current",
"labeling.",
"According",
"to",
"the",
"results",
"of",
"PNFP-343,",
"combination",
"with",
"insulin,",
"edema",
"was",
"observed",
"more",
"often",
"than",
"Avandia,",
"which",
"dose",
"not",
"have",
"the",
"indication",
"for",
"combination",
"with",
"insulin",
"and",
"CHF",
"in",
"this",
"study",
"seems",
"to",
"be",
"dose",
"related.",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-THOMCL-00005583",
"Produced",
"in",
"MDL",
"on",
"09/14/12",
"Source:",
"https://www.indupt2290-coots.ucsf.edu/docs/syjf0226"
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] | {
"match_score": 1,
"matched_text": "CEOs and General Managers of Pharmaceutical Units",
"start": 39,
"text": "CEOs and General Managers of Pharmaceutical Units"
} | {"gt_parses": [{"question" : "what is mentioned in the CC?", "answer" : "CEOs and General Managers of Pharmaceutical Units"}, {"question" : "what is mentioned in the CC?", "answer" : "CEOs and general managers of pharmaceutical units"}]} |
train_435 | null | {
"de": "kombinationstherapie im us-markt macht aus, wie viel % des gesamten actos-umsatzes.",
"en": "combination therapy in the us market accounts for how much % of total actos sales .",
"es": "la terapia de combinación en el mercado de nosotros representa cuánto % de las ventas totales de actos.",
"fr": "la thérapie combinée sur le marché de nous représente combien de % des ventes totales d'actos.",
"it": "la terapia di combinazione nel nostro mercato rappresenta la percentuale delle vendite totali di atti."
} | [
"64",
"64%"
] | [
"8",
"January",
"2003",
"To:",
"MPDRAP",
"I",
"Leader",
"cc:",
"CEOs",
"and",
"General",
"Managers",
"of",
"Pharmaceutical",
"Units",
"My",
"Concerns",
"about",
"sNDA",
"for",
"Actos",
"45mg",
"in",
"the",
"USA",
"(Reconfirmation)",
"Pharmaceutical",
"International",
"Division",
"Y.",
"Narai",
"I",
"express",
"my",
"opinion",
"about",
"the",
"conclusion",
"drawn",
"at",
"MPDRAP",
"Committee",
"Meeting",
"where",
"it",
"was",
"agreed",
"that",
"sNDA",
"to",
"obtain",
"the",
"approval",
"of",
"the",
"45mg",
"combination",
"indications",
"would",
"be",
"submitted,",
"as",
"well",
"as",
"the",
"safety",
"update",
"based",
"on",
"the",
"commitment",
"studies.",
"As",
"you",
"know,",
"Actos",
"is",
"the",
"essential",
"product",
"for",
"IPNA",
"and",
"is",
"vital",
"to",
"the",
"survival",
"of",
"TPNA.",
"If",
"unfavorable",
"revisions",
"in",
"the",
"Actos",
"labeling",
"are",
"made,",
"it",
"invites",
"the",
"serious",
"risk",
"to",
"Actos",
"in",
"the",
"US.",
"TPNA",
"is",
"now",
"under",
"attack",
"from",
"GSK,",
"especially",
"by",
"Avandamet",
"and",
"is",
"eager",
"to",
"maintain",
"their",
"market",
"share.",
"In",
"addition",
"to",
"this",
"attack,",
"if",
"the",
"indications",
"of",
"Actos",
"are",
"reduced,",
"TPNA",
"is",
"pushed",
"into",
"critical",
"situation.",
"This",
"issue",
"seriously",
"damages",
"not",
"only",
"US",
"market",
"but",
"also",
"Takeda's",
"global",
"strategy.",
"Therefore,",
"HQ",
"should",
"be",
"extremely",
"cautious",
"about",
"the",
"issues",
"related",
"to",
"Actos.",
"If",
"this",
"sNDA",
"raises",
"the",
"argument",
"for",
"the",
"indications",
"of",
"Actos,",
"for",
"example,",
"reductions",
"in",
"the",
"indications,",
"the",
"issues",
"will",
"come",
"to",
"a",
"critical",
"path",
"like",
"as",
"I",
"mentioned.",
"So",
"we",
"should",
"go",
"into",
"action",
"on",
"condition",
"that",
"there",
"is",
"no",
"such",
"risk.",
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"therapy",
"in",
"the",
"US",
"market",
"accounts",
"for",
"64%",
"of",
"total",
"Actos",
"sales.",
"(29%",
"in",
"combination",
"with",
"SU,",
"27%",
"Metformin",
"and",
"8%",
"Insulin)",
"Regarding",
"the",
"possibility",
"of",
"the",
"risk",
"of",
"labeling",
"revision,",
"International",
"Division",
"entrusts",
"Development",
"Division",
"with",
"final",
"decision.",
"However,",
"just",
"to",
"be",
"sure,",
"I",
"would",
"like",
"to",
"reconfirm",
"that",
"this",
"sNDA",
"dose",
"not",
"lead",
"to",
"a",
"serious",
"situation.",
"I",
"heard",
"that",
"TPNA",
"R&D",
"suggested",
"to",
"HQ",
"and",
"is",
"getting",
"ready",
"for",
"sNDA",
"for",
"the",
"45mg",
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"indications.",
"However,",
"HQ",
"should",
"carefully",
"judge",
"whether",
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"should",
"be",
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"to",
"the",
"FDA",
"or",
"not.",
"I",
"think",
"that",
"sNDA",
"for",
"efficacy",
"should",
"be",
"submitted",
"only",
"when",
"there",
"is",
"no",
"risk",
"that",
"this",
"sND",
"A",
"damages",
"the",
"current",
"labeling.",
"According",
"to",
"the",
"results",
"of",
"PNFP-343,",
"combination",
"with",
"insulin,",
"edema",
"was",
"observed",
"more",
"often",
"than",
"Avandia,",
"which",
"dose",
"not",
"have",
"the",
"indication",
"for",
"combination",
"with",
"insulin",
"and",
"CHF",
"in",
"this",
"study",
"seems",
"to",
"be",
"dose",
"related.",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-THOMCL-00005583",
"Produced",
"in",
"MDL",
"on",
"09/14/12",
"Source:",
"https://www.indupt2290-coots.ucsf.edu/docs/syjf0226"
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train_436 | null | {
"de": "Was ist der Fälligkeitstermin für die Auswertung der Daten von actos 507?",
"en": "What is the due date to evaluate data from actos 507?",
"es": "¿Cuál es la fecha de vencimiento para evaluar los datos de actos 507?",
"fr": "Quelle est la date limite pour évaluer les données des actos 507?",
"it": "Qual è la data di scadenza per la valutazione dei dati da actos 507?"
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"match_score": 1,
"matched_text": "August 5",
"start": 141,
"text": "August 5"
} | {"gt_parses": [{"question" : "What is the due date to evaluate data from actos 507?", "answer" : "August 5"}]} |
train_437 | null | {
"de": "wer ist die federführende Verantwortung für die Entwicklung eines zusätzlichen Monitoringplans für actos 508",
"en": "who is the lead responsibility for developing additional monitoring plan for actos 508",
"es": "quién es el principal responsable de desarrollar un plan de seguimiento adicional para los actos 508",
"fr": "qui est responsable au premier chef de l'élaboration d'un plan de surveillance supplémentaire pour les actos 508",
"it": "che è la responsabilità principale dello sviluppo di un piano di monitoraggio supplementare per gli atti 508"
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} | {"gt_parses": [{"question" : "who is the lead responsibility for developing additional monitoring plan for actos 508", "answer" : "Amy Hagaman"}, {"question" : "who is the lead responsibility for developing additional monitoring plan for actos 508", "answer" : "Amy hagaman"}]} |
train_438 | null | {
"de": "was ist der Fälligkeitstermin für den \"Entwurf der Begründung für actos 508\"?",
"en": "what is the due date for \"draft justification for actos 508\" ?",
"es": "¿Cuál es la fecha de vencimiento del \"proyecto de justificación de actos 508\"?",
"fr": "Quelle est la date d'échéance pour \"projet de justification pour actos 508\"?",
"it": "Qual è la data di scadenza per il \"progetto di giustificazione per attos 508\"?"
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"match_score": 1,
"matched_text": "August 12",
"start": 514,
"text": "August 12"
} | {"gt_parses": [{"question" : "what is the due date for \"draft justification for actos 508\" ?", "answer" : "August 12"}, {"question" : "what is the due date for \"draft justification for actos 508\" ?", "answer" : "august 12"}]} |
train_439 | null | {
"de": "Wann wurde diese zuletzt aktualisiert?",
"en": "when was this last updated ?",
"es": "¿Cuándo se actualizó por última vez?",
"fr": "Quand a-t-il été mis à jour pour la dernière fois?",
"it": "Quando è stata aggiornata l'ultima volta?"
} | [
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"august 1, 2002"
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"match_score": 1,
"matched_text": "August 1, 2002",
"start": 680,
"text": "August 1, 2002"
} | {"gt_parses": [{"question" : "when was this last updated ?", "answer" : "August 1, 2002"}, {"question" : "when was this last updated ?", "answer" : "august 1, 2002"}]} |
train_441 | null | {
"de": "Welches ist die Kernorganisation von Takeda Pharma Company?",
"en": "Which is the core organization of Takeda pharmaceutical Company?",
"es": "¿Cuál es la organización principal de Takeda Pharmaceutical Company?",
"fr": "Quelle est l'organisation principale de Takeda Pharmaceutical Company?",
"it": "Qual è l'organizzazione centrale della Takeda Pharmaceutical Company?"
} | [
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] | {
"match_score": 0.971428572244898,
"matched_text": "Pharmaceutical Development Division",
"start": 395,
"text": "Pharmaceutical development Division"
} | {"gt_parses": [{"question" : "Which is the core organization of Takeda pharmaceutical Company?", "answer" : "Pharmaceutical development Division"}, {"question" : "Which is the core organization of Takeda pharmaceutical Company?", "answer" : "Pharmaceutical Development Division"}]} |
train_442 | null | {
"de": "Wer hat die einleitenden Bemerkungen gemacht?",
"en": "Who made the opening remarks ?",
"es": "¿Quién hizo el discurso de apertura?",
"fr": "Qui a fait les remarques d'ouverture?",
"it": "Chi ha fatto le osservazioni di apertura?"
} | [
"Dr. Kitazawa"
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train_443 | null | {
"de": "Wann ist das klinische Expertentreffen geplant?",
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"es": "¿Cuándo está programada la reunión de expertos clínicos?",
"fr": "Quand est prévue la réunion d'experts cliniques?",
"it": "Quando è prevista la riunione degli esperti clinici?"
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"matched_text": "for October 1 and 2 ",
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train_444 | null | {
"de": "Was ist das Datum, das in den gegebenen Informationen erwähnt wird?",
"en": "what is the date mentioned in the given information ?",
"es": "¿Cuál es la fecha mencionada en la información dada?",
"fr": "Quelle est la date mentionnée dans l'information donnée?",
"it": "Qual è la data indicata nelle informazioni fornite?"
} | [
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train_445 | null | {
"de": "Was ist die hier erwähnte Sitzungszeit?",
"en": "What is the meeting time mentioned here?",
"es": "¿Cuál es el tiempo de reunión mencionado aquí?",
"fr": "Quel est le temps de réunion mentionné ici?",
"it": "Qual è l'orario di riunione qui menzionato?"
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"match_score": 1,
"matched_text": "4:00pm - 5:00pm",
"start": 56,
"text": "4:00pm - 5:00pm"
} | {"gt_parses": [{"question" : "What is the meeting time mentioned here?", "answer" : "4:00pm - 5:00pm"}]} |
train_446 | null | {
"de": "Was ist der Ort erwähnt?",
"en": "what is the place mentioned ?",
"es": "¿Cuál es el lugar mencionado?",
"fr": "quel est l'endroit mentionné?",
"it": "Qual è il luogo menzionato?"
} | [
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"matched_text": "Meeting Room 403",
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"text": "Meeting Room 403"
} | {"gt_parses": [{"question" : "what is the place mentioned ?", "answer" : "Meeting Room 403"}, {"question" : "what is the place mentioned ?", "answer" : "meeting room 403"}]} |
train_447 | null | {
"de": "Warum wurde vorgeschlagen, nicht-klinisches \"Weißpapier\" vorzubereiten?",
"en": "Why was it suggested to prepare non-clinical \"White paper\"?",
"es": "¿Por qué se sugirió preparar un \"papel blanco\" no clínico?",
"fr": "Pourquoi a-t-on suggéré de préparer un «papier blanc» non clinique?",
"it": "Perché è stato suggerito di preparare la \"carta bianca\" non clinica?"
} | [
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"under",
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"Development",
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"enhancing",
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"and",
"lack",
"of",
"challenging",
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"this",
"conservative",
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"grow",
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"3.",
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"(Diabetes)",
"1)",
"AD-4833",
"Update",
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"status",
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"508)",
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"on",
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"to",
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"prepare",
"non-clinical",
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"the",
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"45mg",
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"341,",
"342,",
"343",
"and",
"513",
"are",
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"purpose,",
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"45mg,",
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"results",
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"the",
"label.",
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"and",
"issues",
"on",
"Actos",
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"projects",
"were",
"presented.",
"Actos-Metformin",
"Convenience",
"Pack",
"is",
"expected",
"to",
"file",
"sNDA",
"in",
"March",
"2003",
"and",
"to",
"be",
"approved",
"in",
"September",
"2003.",
"TPNA",
"believes",
"stability",
"data",
"of",
"3",
"months",
"are",
"sufficient",
"2",
"Confidential",
"-",
"Subject",
"to",
"Protective",
"Order",
"TAK-THOMCL-00012574",
"Source:",
"https://www.indupto442coo02ts.ucsf.edu/docs/Imjf0226",
"Produced",
"in",
"MDL",
"on",
"09/14/12"
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train_448 | null | {
"de": "Wer wird den Artikel über Rosiglitazon und nicht klinische Blasendaten an Andy weiterleiten?",
"en": "who will forward the article regarding rosiglitazone and non clinical bladder data to andy ?",
"es": "¿Quién enviará el artículo sobre rosiglitazona y datos no clínicos de vejiga a Andy?",
"fr": "qui transmettra l'article sur la rosiglitazone et les données non cliniques de la vessie à l'andy?",
"it": "chi trasmetterà all' Andy l' articolo relativo ai dati relativi a rosiglitazone e alla vescica non clinica?"
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"match_score": 1,
"matched_text": "in early May",
"start": 665,
"text": "in early May"
} | {"gt_parses": [{"question" : "What date is the meeting scheduled to develop the overall structure of the document?", "answer" : "in early May"}]} |
train_450 | null | {
"de": "Wer stellte einen Umriss der Cohen-Hypothese vor?",
"en": "Who presented an outline of the Cohen hypothesis?",
"es": "¿Quién presentó un esquema de la hipótesis de Cohen?",
"fr": "Qui a présenté un aperçu de l'hypothèse de Cohen?",
"it": "Chi ha presentato uno schema dell'ipotesi Cohen?"
} | [
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"match_score": 1,
"matched_text": "Philip Collett",
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"text": "Philip Collett"
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train_451 | null | {
"de": "Was ist bei der Entwicklung von Kalkülen von Bedeutung?",
"en": "What is significant in the development of calculi?",
"es": "¿Qué es significativo en el desarrollo de los cálculos?",
"fr": "Qu'est-ce qui est significatif dans le développement des calculs?",
"it": "Cosa c'è di significativo nello sviluppo dei calcoli?"
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] | {
"match_score": 1,
"matched_text": "Raising the pH of male rat urine above 6.5",
"start": 248,
"text": "Raising the pH of male rat urine above 6.5"
} | {"gt_parses": [{"question" : "What is significant in the development of calculi?", "answer" : "Raising the pH of male rat urine above 6.5"}]} |
train_452 | null | {
"de": "Was ist die Korrelation, die in cohens Papier beobachtet wird?",
"en": "What is the correlation observed in cohen's paper?",
"es": "¿Cuál es la correlación observada en el papel de Cohen?",
"fr": "Quelle est la corrélation observée dans l'article de Cohen?",
"it": "Qual è la correlazione osservata nel documento di Cohen?"
} | [
"0.61"
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"Source:",
"https://www.indug2/pg-00604s.ucsf.edu/docs/myjf0226"
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"match_score": 1,
"matched_text": "0.61",
"start": 453,
"text": "0.61"
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train_453 | null | {
"de": "Warum haben Ratten keine Kalküle eliminiert, wie es der Mensch tut?",
"en": "Why didn't rats eliminate calculi as humans do?",
"es": "¿Por qué las ratas no eliminaron los cálculos como los humanos?",
"fr": "Pourquoi les rats n'ont-ils pas éliminé les calculi comme les humains?",
"it": "Perché i ratti non eliminano i calcoli come fanno gli umani?"
} | [
"Because rats are quadropeds",
"Because rats are quadropeds."
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train_455 | null | {
"de": "Welches Forum wird in diesem Dokument erwähnt?",
"en": "Which forum is mentioned in this document?",
"es": "¿Qué foro se menciona en este documento?",
"fr": "Quel forum est mentionné dans ce document?",
"it": "Quale forum è menzionato in questo documento?"
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train_456 | null | {
"de": "Wie lautet das ausgestellte Datum dieses Dokuments?",
"en": "What is the issued date of this document?",
"es": "¿Cuál es la fecha de publicación de este documento?",
"fr": "Quelle est la date de publication de ce document?",
"it": "Qual è la data di rilascio di questo documento?"
} | [
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train_457 | null | {
"de": "Wer ist der Direktor für nichtklinische Sicherheit und Wirksamkeit?",
"en": "Who is the Director of Nonclinical Safety and Efficacy?",
"es": "¿Quién es el Director de Seguridad y Eficacia No Clínica?",
"fr": "Qui est le directeur de la sécurité et de l'efficacité non cliniques?",
"it": "Chi è il Direttore di Sicurezza ed Efficacia Non Clinica?"
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train_459 | null | {
"de": "Wie lange dauert die tägliche Dosierung?",
"en": "What is the duration of daily dosing?",
"es": "¿Cuál es la duración de la dosis diaria?",
"fr": "Quelle est la durée de l'administration quotidienne?",
"it": "Qual è la durata della somministrazione giornaliera?"
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"match_score": 1,
"matched_text": "32-weeks",
"start": 1703,
"text": "32-weeks"
} | {"gt_parses": [{"question" : "What is the duration of daily dosing?", "answer" : "32-weeks"}, {"question" : "What is the duration of daily dosing?", "answer" : "32-weeks after BBN."}]} |
train_460 | null | {
"de": "Wer hat den CEO am 6. August aktualisiert?",
"en": "Who updated the CEO on August 6?",
"es": "¿Quién actualizó el CEO el 6 de agosto?",
"fr": "Qui a mis à jour le PDG le 6 août?",
"it": "Chi ha aggiornato il CEO il 6 agosto?"
} | [
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"match_score": 1,
"matched_text": "Mr. Saito",
"start": 542,
"text": "Mr. Saito"
} | {"gt_parses": [{"question" : "Who updated the CEO on August 6?", "answer" : "Mr. Saito"}]} |
train_461 | null | {
"de": "Bis wann sollte TPNA einen Überblick über die Antwort auf TCI senden?",
"en": "By when should TPNA send outline of response to TCI ?",
"es": "¿Para cuándo debe TPNA enviar el esquema de respuesta a TCI?",
"fr": "Quand l'ACPT devrait-elle envoyer un aperçu de la réponse à l'ICT?",
"it": "Entro quando il TPNA dovrebbe inviare una descrizione della risposta al TCI?"
} | [
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"match_score": 1,
"matched_text": "August 19",
"start": 1154,
"text": "August 19"
} | {"gt_parses": [{"question" : "By when should TPNA send outline of response to TCI ?", "answer" : "August 19"}, {"question" : "By when should TPNA send outline of response to TCI ?", "answer" : "by August 19"}]} |
train_462 | null | {
"de": "Wann wird Mr. Saito dem CEO einen Überblick geben?",
"en": "When will Mr. Saito present outline to CEO?",
"es": "¿Cuándo presentará el Sr. Saito un esquema al CEO?",
"fr": "Quand M. Saito présentera-t-il les grandes lignes au PDG?",
"it": "Quando il signor Saito presenterà il profilo all'amministratore delegato?"
} | [
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"match_score": 1,
"matched_text": "August 20",
"start": 1205,
"text": "August 20"
} | {"gt_parses": [{"question" : "When will Mr. Saito present outline to CEO?", "answer" : "August 20"}, {"question" : "When will Mr. Saito present outline to CEO?", "answer" : "on August 20"}]} |