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| first_mask_count
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int64 0
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<|startoftext|><L>CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N<mask_1:4>c1<mask_1:4> | 1 | 39 | 4 | ) | 4 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(NCCO)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | CCO) |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)c<mask_1:5>(N)c1<mask_1:5> | 4 | 33 | 5 | c2)c | 5 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2C)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | c2C)c |
<|startoftext|><L>CC<mask_1:2>(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1<mask_1:2> | 6 | 2 | 2 | N(CC)S | 2 | CCNS(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | NS |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1<mask_1:6>c(Oc2ccc(Cl)cc2)c(N)c1<mask_1:6> | 2 | 18 | 6 | cc | 6 | CCN(CC)S(=O)(=O)c1cc(Cl)c(Oc2ccc(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | cc(Cl) |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc<mask_1:6>)c1<mask_1:6> | 5 | 34 | 6 | 2)c(N | 6 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(Br)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | 2)c(Br |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1ccc(Oc<mask_1:2>(Cl)cc2)c(N)c1<mask_1:2> | 4 | 24 | 2 | 2ccc | 2 | CCN(CC)S(=O)(=O)c1ccc(Oc2c(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | 2c |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1c<mask_1:4>c(Oc2ccc(Cl)cc2)c(N)c1<mask_1:4> | 1 | 19 | 4 | c | 4 | CCN(CC)S(=O)(=O)c1cc(N)c(Oc2ccc(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | c(N) |
<|startoftext|><L>CCN(CC)S(=O)(=<mask_1:4>c1ccc(Oc2ccc(Cl)cc2)c(N)c1<mask_1:4> | 2 | 14 | 4 | O) | 4 | CCN(CC)S(=O)(=O)NCc1ccc(Oc2ccc(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | O)NC |
<|startoftext|><L>CCN(CC)S(=O)(=O<mask_1:3>c(Oc2ccc(Cl)cc2)c(N)c1<mask_1:3> | 5 | 15 | 3 | )c1cc | 3 | CCN(CC)S(=O)(=O)c1c(Oc2ccc(Cl)cc2)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | )c1 |
<|startoftext|><L>CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)<mask_1:6>c(N)c1<mask_1:6> | 4 | 32 | 6 | cc2) | 6 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2Cl)c(N)c1 | CCN(CC)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)c(N)c1 | cc2Cl) |
<|startoftext|><L>Cc1nn(CC(F)F)cc1<mask_1:3>=O)N1CCC(c2cc(O)no2)CC1<mask_1:3> | 2 | 16 | 3 | C( | 3 | Cc1nn(CC(F)F)cc1NC(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | NC( |
<|startoftext|><L>Cc1nn(CC(F)F)<mask_1:6>=O)N1CCC(c2cc(O)no2)CC1<mask_1:6> | 5 | 13 | 6 | cc1C( | 6 | Cc1nn(CC(F)F)cc1NC(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | cc1NC( |
<|startoftext|><L>Cc1nn(CC(F)F)cc1C(=O)<mask_1:5>CC(c2cc(O)no2)CC1<mask_1:5> | 3 | 21 | 5 | N1C | 5 | Cc1nn(CC(F)F)cc1C(=O)NCC1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | NCC1C |
<|startoftext|><L>Cc1nn(CC(F)F)c<mask_1:6>1C(=O)N1CCC(c2cc(O)no2)CC1<mask_1:6> | 1 | 14 | 6 | c | 6 | Cc1nn(CC(F)F)c(C#N)c1C(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | (C#N)c |
<|startoftext|><L>Cc1nn(CC(F)F<mask_1:5>c1C(=O)N1CCC(c2cc(O)no2)CC1<mask_1:5> | 2 | 12 | 5 | )c | 5 | Cc1nn(CC(F)F)c(C)c1C(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | )c(C) |
<|startoftext|><L>Cc1nn(CC(F)F)cc1C(=O)<mask_1:6>N1CCC(c2cc(O)no2)CC1<mask_1:6> | 0 | 21 | 6 | 6 | Cc1nn(CC(F)F)cc1C(=O)NC(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | NC(=O) |
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<|startoftext|><L>Cc1nn(CC<mask_1:4>cc1C(=O)N1CCC(c2cc(O)no2)CC1<mask_1:4> | 5 | 8 | 4 | (F)F) | 4 | Cc1nn(CCCCO)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | CCO) |
<|startoftext|><L>Cc1nn(CC(F)F)cc1C(=O)N1<mask_1:1>CCC(c2cc(O)no2)CC1<mask_1:1> | 0 | 23 | 1 | 1 | Cc1nn(CC(F)F)cc1C(=O)N1CCCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | C |
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<|startoftext|><L>Cc1nn(CC(F)F)cc1C<mask_1:6>(=O)N1CCC(c2cc(O)no2)CC1<mask_1:6> | 0 | 17 | 6 | 6 | Cc1nn(CC(F)F)cc1C(=O)NC(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | (=O)NC |
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<|startoftext|><L>Cc1nn(CC(F)F)cc<mask_1:3>C(=O)N1CCC(c2cc(O)no2)CC1<mask_1:3> | 1 | 15 | 3 | 1 | 3 | Cc1nn(CC(F)F)cc1CNC(=O)N1CCC(c2cc(O)no2)CC1 | Cc1nn(CC(F)F)cc1C(=O)N1CCC(c2cc(O)no2)CC1 | 1CN |
<|startoftext|><L>Brc1c(<mask_1:2>c2ccccc2)nc2ncccn12<mask_1:2> | 1 | 6 | 2 | - | 2 | Brc1c(NCc2ccccc2)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | NC |
<|startoftext|><L>Brc1c(-c2c<mask_1:1>cc2)nc2ncccn12<mask_1:1> | 2 | 10 | 1 | cc | 1 | Brc1c(-c2cscc2)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | s |
<|startoftext|><L>Brc1c(-c2ccccc2<mask_1:3>nc2ncccn12<mask_1:3> | 1 | 15 | 3 | ) | 3 | Brc1c(-c2ccccc2Br)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | Br) |
<|startoftext|><L>B<mask_1:3>c1c(-c2ccccc2)nc2ncccn12<mask_1:3> | 1 | 1 | 3 | r | 3 | BrCCc1c(-c2ccccc2)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | rCC |
<|startoftext|><L>Brc1c(-c2ccccc2)nc<mask_1:2>ccn12<mask_1:2> | 3 | 18 | 2 | 2nc | 2 | Brc1c(-c2ccccc2)nc2sccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | 2s |
<|startoftext|><L><mask_1:1>1c(-c2ccccc2)nc2ncccn12<mask_1:1> | 3 | 0 | 1 | Brc | 1 | c1c(-c2ccccc2)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | c |
<|startoftext|><L><mask_1:1>1c(-c2ccccc2)nc2ncccn12<mask_1:1> | 3 | 0 | 1 | Brc | 1 | c1c(-c2ccccc2)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | c |
<|startoftext|><L>Brc1c(-c2ccccc2<mask_1:2>2ncccn12<mask_1:2> | 3 | 15 | 2 | )nc | 2 | Brc1c(-c2ccccc2)n2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | )n |
<|startoftext|><L>Brc1c(-c2ccccc2)nc<mask_1:1>ccn12<mask_1:1> | 3 | 18 | 1 | 2nc | 1 | Brc1c(-c2ccccc2)nc2ccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | 2 |
<|startoftext|><L>Brc1c(-c2ccccc<mask_1:3>)nc2ncccn12<mask_1:3> | 1 | 14 | 3 | 2 | 3 | Brc1c(-c2ccccc2Cl)nc2ncccn12 | Brc1c(-c2ccccc2)nc2ncccn12 | 2Cl |
<|startoftext|><L>CCC[C@@H](C)N1C<mask_1:6>C2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O<mask_1:6> | 0 | 15 | 6 | 6 | CCC[C@@H](C)N1C(=O)NCC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | (=O)NC |
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<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O)<mask_1:5>(F)cc(F)c3)CC2)OC1=O<mask_1:5> | 4 | 27 | 5 | c3cc | 5 | CCC[C@@H](C)N1CC2(CCN(C(=O)Cc3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | Cc3cc |
<|startoftext|><L>CCC[C@<mask_1:6>)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O<mask_1:6> | 5 | 6 | 6 | @H](C | 6 | CCC[C@@H](CO)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | @H](CO |
<|startoftext|><L>C<mask_1:1>CC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O<mask_1:1> | 0 | 1 | 1 | 1 | COCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | O |
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<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)c<mask_1:6>F)c3)CC2)OC1=O<mask_1:6> | 2 | 35 | 6 | c( | 6 | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)c(OC)c(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | (OC)c( |
<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O)c<mask_1:3>cc(F)c3)CC2)OC1=O<mask_1:3> | 6 | 28 | 3 | 3cc(F) | 3 | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cccc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | 3cc |
<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)<mask_1:2>=O<mask_1:2> | 3 | 46 | 2 | OC1 | 2 | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)C1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | C1 |
<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O)c3<mask_1:6>)cc(F)c3)CC2)OC1=O<mask_1:6> | 4 | 29 | 6 | cc(F | 6 | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(C#N)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | cc(C#N |
<|startoftext|><L><mask_1:4>C[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O<mask_1:4> | 2 | 0 | 4 | CC | 4 | CCCCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | CCCC |
<|startoftext|><L>CCC[C@@H](C)N1CC2(CCN(C(=O<mask_1:7>(F)cc(F)c3)CC2)OC1=O<mask_1:7> | 5 | 26 | 7 | )c3cc | 7 | CCC[C@@H](C)N1CC2(CCN(C(=O)CCc3cc(F)cc(F)c3)CC2)OC1=O | CCC[C@@H](C)N1CC2(CCN(C(=O)c3cc(F)cc(F)c3)CC2)OC1=O | )CCc3cc |
<|startoftext|><L>C<mask_1:6>c(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:6> | 5 | 1 | 6 | c1ccc | 6 | CCc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1ccc |
<|startoftext|><L>Cc1cccc(C)c1<mask_1:4>[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:4> | 6 | 12 | 4 | NC(=O) | 4 | Cc1cccc(C)c1OCCC[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | OCCC |
<|startoftext|><L>Cc1<mask_1:1>c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:1> | 7 | 3 | 1 | cccc(C) | 1 | Cc1oc1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | o |
<|startoftext|><L>Cc1cccc(C)c<mask_1:7>(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:7> | 3 | 11 | 7 | 1NC | 7 | Cc1cccc(C)c1NS(=O)(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | 1NS(=O) |
<|startoftext|><L>Cc1cccc(C)c1NC(=O<mask_1:4>)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:4> | 0 | 17 | 4 | 4 | Cc1cccc(C)c1NC(=O)N(C)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | )N(C |
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<|startoftext|><L>Cc1<mask_1:3>c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:3> | 7 | 3 | 3 | cccc(C) | 3 | Cc1ccsc1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | ccs |
<|startoftext|><L>Cc1cccc(C)c1NC(=O)[C@<mask_1:2>1CCC(C(=O)NCc2ccccc2)CC1<mask_1:2> | 7 | 21 | 2 | @H](C)N | 2 | Cc1cccc(C)c1NC(=O)[C@H]1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | H] |
<|startoftext|><L>Cc1cccc(<mask_1:5>1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:5> | 3 | 8 | 5 | C)c | 5 | Cc1cccc(C#N)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | C#N)c |
<|startoftext|><L>Cc1cccc(C)c1NC<mask_1:4>=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1<mask_1:4> | 1 | 14 | 4 | ( | 4 | Cc1cccc(C)c1NCCNC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | CNC( |
<|startoftext|><L>Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc<mask_1:4>CC1<mask_1:4> | 2 | 47 | 4 | 2) | 4 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2Cl)CC1 | Cc1cccc(C)c1NC(=O)[C@@H](C)N1CCC(C(=O)NCc2ccccc2)CC1 | 2Cl) |
<|startoftext|><L>COc1c(F)ccc(C(=O)N2CCC[C@@<mask_1:5>CCCNC3=O)c1F<mask_1:5> | 3 | 26 | 5 | ]23 | 5 | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | ]23CC |
<|startoftext|><L>COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCN<mask_1:3>1F<mask_1:3> | 6 | 33 | 3 | C3=O)c | 3 | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCN3)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | 3)c |
<|startoftext|><L>COc1c(F)ccc(<mask_1:6>=O)N2CCC[C@@]23CCCNC3=O)c1F<mask_1:6> | 2 | 12 | 6 | C( | 6 | COc1c(F)ccc(S(=O)(=O)N2CCC[C@@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | S(=O)( |
<|startoftext|><L>C<mask_1:6>Oc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F<mask_1:6> | 0 | 1 | 6 | 6 | CC(C)CCOc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | C(C)CC |
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<|startoftext|><L>COc1c(F)ccc(C(=O)N2CCC[C@@]23C<mask_1:4>CNC3=O)c1F<mask_1:4> | 1 | 30 | 4 | C | 4 | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCNCCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | CNCC |
<|startoftext|><L>COc1c(F)c<mask_1:6>=O)N2CCC[C@@]23CCCNC3=O)c1F<mask_1:6> | 5 | 9 | 6 | cc(C( | 6 | COc1c(F)ccc(NC(=O)N2CCC[C@@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | cc(NC( |
<|startoftext|><L>COc1c(F)ccc(C(=O)N2CCC[C@<mask_1:4>CNC3=O)c1F<mask_1:4> | 6 | 25 | 4 | @]23CC | 4 | COc1c(F)ccc(C(=O)N2CCC[C@]23CCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | ]23C |
<|startoftext|><L>COc1c(F)ccc(C(=O)N2CCC[C@<mask_1:1>23CCCNC3=O)c1F<mask_1:1> | 2 | 25 | 1 | @] | 1 | COc1c(F)ccc(C(=O)N2CCC[C@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | ] |
<|startoftext|><L>COc1c(F)ccc(C(=O)N2CC<mask_1:3>[C@@]23CCCNC3=O)c1F<mask_1:3> | 1 | 21 | 3 | C | 3 | COc1c(F)ccc(C(=O)N2CCCCC[C@@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | CCC |
<|startoftext|><L>COc1<mask_1:5>)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F<mask_1:5> | 3 | 4 | 5 | c(F | 5 | COc1c(C#N)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | COc1c(F)ccc(C(=O)N2CCC[C@@]23CCCNC3=O)c1F | c(C#N |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)N<mask_1:2>CNC(=O)c1ccccn1<mask_1:2> | 1 | 45 | 2 | C | 2 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | CC |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2<mask_1:8>NCCNC(=O)c1ccccn1<mask_1:8> | 5 | 39 | 8 | C(=O) | 8 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C(=O)NCC |
<|startoftext|><L><mask_1:6>C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1<mask_1:6> | 7 | 0 | 6 | C[C@]12 | 7 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12 |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=<mask_1:7>NC(=O)c1ccccn1<mask_1:7> | 5 | 42 | 7 | O)NCC | 7 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | O)NCCCC |
<|startoftext|><L>C[C@]12C(=O)<mask_1:3>ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1<mask_1:3> | 2 | 12 | 3 | c3 | 3 | C[C@]12C(=O)Nc3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | Nc3 |
<|startoftext|><L>C[C@]12C(=O)c3cc<mask_1:7>)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1<mask_1:7> | 9 | 16 | 7 | ccc3NC(=O | 8 | C[C@]12C(=O)c3ccccc3C(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | ccc3C(=O |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(=O)[C<mask_1:8>]2C(=O)NCCNC(=O)c1ccccn1<mask_1:8> | 9 | 28 | 8 | @@H]1[C@H | 8 | C[C@]12C(=O)c3ccccc3NC(=O)[C@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | @H]1[C@H |
<|startoftext|><L>C[C@<mask_1:7>=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1<mask_1:7> | 5 | 4 | 7 | ]12C( | 7 | C[C@@]12NC(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | @]12NC( |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(<mask_1:5>1[C@H]2C(=O)NCCNC(=O)c1ccccn1<mask_1:5> | 9 | 23 | 5 | =O)[C@@H] | 5 | C[C@]12C(=O)c3ccccc3NC(=O)CN1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | =O)CN |
<|startoftext|><L>C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H<mask_1:9>(=O)NCCNC(=O)c1ccccn1<mask_1:9> | 3 | 37 | 9 | ]2C | 9 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NC(=O)NCCNC(=O)c1ccccn1 | C[C@]12C(=O)c3ccccc3NC(=O)[C@@H]1[C@H]2C(=O)NCCNC(=O)c1ccccn1 | ]2C(=O)NC |
<|startoftext|><L>O=C1C(=Cc2ccccc2I)C(=O)c2cccc<mask_1:3>c21<mask_1:3> | 0 | 29 | 3 | 3 | O=C1C(=Cc2ccccc2I)C(=O)c2cccc(F)c21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | (F) |
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<|startoftext|><L>O=C1<mask_1:2>c2ccccc2I)C(=O)c2ccccc21<mask_1:2> | 4 | 4 | 2 | C(=C | 2 | O=C1N(c2ccccc2I)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | N( |
<|startoftext|><L>O=C1C(=<mask_1:4>c2ccccc2I)C(=O)c2ccccc21<mask_1:4> | 1 | 7 | 4 | C | 4 | O=C1C(=O)N(c2ccccc2I)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | O)N( |
<|startoftext|><L>O=C1C(=Cc2ccccc2<mask_1:2>=O)c2ccccc21<mask_1:2> | 4 | 16 | 2 | I)C( | 2 | O=C1C(=Cc2ccccc2OC=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | OC |
<|startoftext|><L>O<mask_1:2>C1C(=Cc2ccccc2I)C(=O)c2ccccc21<mask_1:2> | 1 | 1 | 2 | = | 2 | O=CC1C(=Cc2ccccc2I)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | =C |
<|startoftext|><L>O=C1C(=Cc2ccccc2I)C<mask_1:3>O)c2ccccc21<mask_1:3> | 2 | 19 | 3 | (= | 3 | O=C1C(=Cc2ccccc2I)CC(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | C(= |
<|startoftext|><L>O=C1C(=C<mask_1:4>cccc2I)C(=O)c2ccccc21<mask_1:4> | 3 | 8 | 4 | c2c | 4 | O=C1C(=CNc2ccccc2I)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | Nc2c |
<|startoftext|><L>O=C1C(=Cc2ccccc2I)<mask_1:1>C(=O)c2ccccc21<mask_1:1> | 0 | 18 | 1 | 1 | O=C1C(=Cc2ccccc2I)CC(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | C |
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<|startoftext|><L>O=C1C(=Cc2ccccc2<mask_1:2>)C(=O)c2ccccc21<mask_1:2> | 1 | 16 | 2 | I | 2 | O=C1C(=Cc2ccccc2Cl)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | Cl |
<|startoftext|><L>O=C1C(=C<mask_1:4>cccc2I)C(=O)c2ccccc21<mask_1:4> | 3 | 8 | 4 | c2c | 4 | O=C1C(=CCc2ccccc2I)C(=O)c2ccccc21 | O=C1C(=Cc2ccccc2I)C(=O)c2ccccc21 | Cc2c |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)<mask_1:6>[C@@H]1CCCC[C@H]1O<mask_1:6> | 0 | 37 | 6 | 6 | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)C(=O)N[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | C(=O)N |
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<|startoftext|><L>CN(C(=O)C1CCN<mask_1:8>)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:8> | 5 | 13 | 8 | (S(=O | 8 | CN(C(=O)C1CCN(CCNS(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | (CCNS(=O |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)<mask_1:4>cccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:4> | 8 | 19 | 4 | (=O)Cc2c | 4 | CN(C(=O)C1CCN(S(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | Cc2c |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)<mask_1:4>1CCCC[C@H]1O<mask_1:4> | 6 | 37 | 4 | [C@@H] | 4 | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)CCCN1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CCCN |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)(=O)C<mask_1:6>2ccccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:6> | 1 | 24 | 6 | c | 6 | CN(C(=O)C1CCN(S(=O)(=O)C/C=C/c2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | /C=C/c |
<|startoftext|><L>CN(C(=O)C<mask_1:4>N(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:4> | 3 | 9 | 4 | 1CC | 4 | CN(C(=O)CN1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | N1CC |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O<mask_1:2>c2ccccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:2> | 6 | 18 | 2 | )(=O)C | 2 | CN(C(=O)C1CCN(S(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | )C |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)(=O)Cc2cccc<mask_1:8>2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:8> | 1 | 30 | 8 | c | 8 | CN(C(=O)C1CCN(S(=O)(=O)Cc2cccc(C(F)F)c2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | (C(F)F)c |
<|startoftext|><L>CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]<mask_1:5>CCCC[C@H]1O<mask_1:5> | 1 | 43 | 5 | 1 | 5 | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H](C)C1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | (C)C1 |
<|startoftext|><L>CN<mask_1:8>C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O<mask_1:8> | 6 | 2 | 8 | (C(=O) | 8 | CN(CC(=O)NC1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)[C@@H]1CCCC[C@H]1O | (CC(=O)N |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CC<mask_1:1>C3)o1)[C@H]1C=C[C@H]2C1<mask_1:1> | 2 | 39 | 1 | CC | 1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | C |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N=C/c1c<mask_1:7>N3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:7> | 4 | 31 | 7 | cc(C | 7 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(OCCCN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | cc(OCCC |
<|startoftext|><L>O=C1[C@H<mask_1:4>[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:4> | 2 | 8 | 4 | ]2 | 4 | O=C1[C@H]2CC[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | ]2CC |
<|startoftext|><L>O=C<mask_1:5>C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:5> | 2 | 3 | 5 | 1[ | 5 | O=C1C=C[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | 1C=C[ |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C<mask_1:6>2C1<mask_1:6> | 5 | 56 | 6 | [C@H] | 6 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | [C@@H] |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN<mask_1:1>1)[C@H]1C=C[C@H]2C1<mask_1:1> | 9 | 36 | 1 | 3CCCCC3)o | 1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN)1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | ) |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N<mask_1:9>ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:9> | 5 | 25 | 9 | =C/c1 | 9 | O=C1[C@H]2[C@H](C(=O)N1/N=C/C=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | =C/C=C/c1 |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[<mask_1:3>1<mask_1:3> | 6 | 57 | 3 | C@H]2C | 3 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C]21 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | C]2 |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=<mask_1:4>C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:4> | 7 | 19 | 4 | O)N1/N= | 4 | O=C1[C@H]2[C@H](C(=O)N1C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O)N1 |
<|startoftext|><L>O=C1[C@H]2[C@H](C(=O)N1/<mask_1:9>=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1<mask_1:9> | 1 | 24 | 9 | N | 9 | O=C1[C@H]2[C@H](C(=O)N1/N=C/C=C/C=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | O=C1[C@H]2[C@H](C(=O)N1/N=C/c1ccc(CN3CCCCC3)o1)[C@H]1C=C[C@H]2C1 | N=C/C=C/C |