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{
"aliases": null,
"definition": "A dicarboxylic acid that is butanedioic acid substituted at position 2 by a methyl group.",
"id": "2MethylbutanedioicAcid",
"label": "2-methylbutanedioic acid",
"logical_definition": null,
"original_id": "CHEBI:91315",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "Methylsuccinate"
},
{
"predicate": "subClassOf",
"target": "DicarboxylicAcid"
}
]
} | 0 | {
"document": "2-methylbutanedioic acid A dicarboxylic acid that is butanedioic acid substituted at position 2 by a methyl group. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': 'Methylsuccinate'}, {'predicate': 'subClassOf', 'target': 'DicarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "Increased concentration of 2-methylbutyryl glycine in the urine.",
"id": "2MethylbutyrylGlycinuria",
"label": "2-Methylbutyryl glycinuria",
"logical_definition": null,
"original_id": "HP:0020147",
"relationships": [
{
"predicate": "subClassOf",
"target": "IncreasedUrineProteinogenicAminoAcidDerivativeLevel"
}
]
} | 0 | {
"document": "2-Methylbutyryl glycinuria Increased concentration of 2-methylbutyryl glycine in the urine. [{'predicate': 'subClassOf', 'target': 'IncreasedUrineProteinogenicAminoAcidDerivativeLevel'}]"
} |
{
"aliases": null,
"definition": "Any monocarboxylic acid having a 2-oxo substituent.",
"id": "2OxoMonocarboxylicAcid",
"label": "2-oxo monocarboxylic acid",
"logical_definition": null,
"original_id": "CHEBI:35910",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "2OxoMonocarboxylicAcidAnion"
},
{
"predicate": "subClassOf",
"target": "OxoMonocarboxylicAcid"
}
]
} | 0 | {
"document": "2-oxo monocarboxylic acid Any monocarboxylic acid having a 2-oxo substituent. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '2OxoMonocarboxylicAcidAnion'}, {'predicate': 'subClassOf', 'target': 'OxoMonocarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "An oxo monocarboxylic acid anion in which the oxo group is located at the 2-position.",
"id": "2OxoMonocarboxylicAcidAnion",
"label": "2-oxo monocarboxylic acid anion",
"logical_definition": null,
"original_id": "CHEBI:35179",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "2OxoMonocarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "OxoMonocarboxylicAcidAnion"
}
]
} | 0 | {
"document": "2-oxo monocarboxylic acid anion An oxo monocarboxylic acid anion in which the oxo group is located at the 2-position. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '2OxoMonocarboxylicAcid'}, {'predicate': 'subClassOf', 'target': 'OxoMonocarboxylicAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A dicarboxylic acid monoanion resulting from selective deprotonation of the 1-carboxy group of 2-oxoglutaric acid.",
"id": "2Oxoglutarate1_",
"label": "2-oxoglutarate(1-)",
"logical_definition": null,
"original_id": "CHEBI:30916",
"relationships": [
{
"predicate": "HasRole",
"target": "FundamentalMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Glutarate1_"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "2Oxoglutarate2_"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "2OxoglutaricAcid"
},
{
"predicate": "subClassOf",
"target": "DicarboxylicAcidMonoanion"
}
]
} | 0 | {
"document": "2-oxoglutarate(1-) A dicarboxylic acid monoanion resulting from selective deprotonation of the 1-carboxy group of 2-oxoglutaric acid. [{'predicate': 'HasRole', 'target': 'FundamentalMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Glutarate1_'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '2Oxoglutarate2_'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '2OxoglutaricAcid'}, {'predicate': 'subClassOf', 'target': 'DicarboxylicAcidMonoanion'}]"
} |
{
"aliases": null,
"definition": "An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.",
"id": "2Oxoglutarate2_",
"label": "2-oxoglutarate(2-)",
"logical_definition": null,
"original_id": "CHEBI:16810",
"relationships": [
{
"predicate": "HasRole",
"target": "Geroprotector"
},
{
"predicate": "HasRole",
"target": "SaccharomycesCerevisiaeMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "HasRole",
"target": "AlgalMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Glutarate2_"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "2Oxoglutarate1_"
},
{
"predicate": "subClassOf",
"target": "OxoDicarboxylate"
}
]
} | 0 | {
"document": "2-oxoglutarate(2-) An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. [{'predicate': 'HasRole', 'target': 'Geroprotector'}, {'predicate': 'HasRole', 'target': 'SaccharomycesCerevisiaeMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'HasRole', 'target': 'AlgalMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Glutarate2_'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '2Oxoglutarate1_'}, {'predicate': 'subClassOf', 'target': 'OxoDicarboxylate'}]"
} |
{
"aliases": null,
"definition": "An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle.",
"id": "2OxoglutaricAcid",
"label": "2-oxoglutaric acid",
"logical_definition": null,
"original_id": "CHEBI:30915",
"relationships": [
{
"predicate": "HasRole",
"target": "FundamentalMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "GlutaricAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "2Oxoglutarate1_"
},
{
"predicate": "subClassOf",
"target": "OxoDicarboxylicAcid"
}
]
} | 0 | {
"document": "2-oxoglutaric acid An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. [{'predicate': 'HasRole', 'target': 'FundamentalMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'GlutaricAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '2Oxoglutarate1_'}, {'predicate': 'subClassOf', 'target': 'OxoDicarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid.",
"id": "2SaturatedFattyAcidAnion",
"label": "2-saturated fatty acid anion",
"logical_definition": null,
"original_id": "CHEBI:83955",
"relationships": [
{
"predicate": "subClassOf",
"target": "FattyAcidAnion"
}
]
} | 0 | {
"document": "2-saturated fatty acid anion A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid. [{'predicate': 'subClassOf', 'target': 'FattyAcidAnion'}]"
} |
{
"aliases": null,
"definition": null,
"id": "2nd5thToeMiddlePhalangealHypoplasia",
"label": "2nd-5th toe middle phalangeal hypoplasia",
"logical_definition": null,
"original_id": "HP:0008083",
"relationships": [
{
"predicate": "subClassOf",
"target": "ShortMiddlePhalanxOfToe"
}
]
} | 0 | {
"document": "2nd-5th toe middle phalangeal hypoplasia None [{'predicate': 'subClassOf', 'target': 'ShortMiddlePhalanxOfToe'}]"
} |
{
"aliases": null,
"definition": "An ectoderm that is part of a pharyngeal arch 2.",
"id": "2ndArchEctoderm",
"label": "2nd arch ectoderm",
"logical_definition": null,
"original_id": "UBERON:0005660",
"relationships": null
} | 0 | {
"document": "2nd arch ectoderm An ectoderm that is part of a pharyngeal arch 2. None"
} |
{
"aliases": null,
"definition": "An endoderm that is part of a pharyngeal arch 2.",
"id": "2ndArchEndoderm",
"label": "2nd arch endoderm",
"logical_definition": null,
"original_id": "UBERON:0005664",
"relationships": null
} | 0 | {
"document": "2nd arch endoderm An endoderm that is part of a pharyngeal arch 2. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that is part of a pharyngeal arch 2.",
"id": "2ndArchMesenchyme",
"label": "2nd arch mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0005689",
"relationships": null
} | 0 | {
"document": "2nd arch mesenchyme Mesenchyme that is part of a pharyngeal arch 2. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme.",
"id": "2ndArchMesenchymeFromHeadMesenchyme",
"label": "2nd arch mesenchyme from head mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0010343",
"relationships": [
{
"predicate": "PartOf",
"target": "2ndArchMesenchyme"
},
{
"predicate": "DevelopsFrom",
"target": "HeadMesenchymeFromMesoderm"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "2nd arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme. [{'predicate': 'PartOf', 'target': '2ndArchMesenchyme'}, {'predicate': 'DevelopsFrom', 'target': 'HeadMesenchymeFromMesoderm'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme.",
"id": "2ndArchMesenchymeFromNeuralCrest",
"label": "2nd arch mesenchyme from neural crest",
"logical_definition": null,
"original_id": "UBERON:0010254",
"relationships": [
{
"predicate": "PartOf",
"target": "2ndArchMesenchyme"
},
{
"predicate": "PartOf",
"target": "MesenchymeFromRhombencephalicNeuralCrest"
},
{
"predicate": "DevelopsFrom",
"target": "HyoidNeuralCrest"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "2nd arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme. [{'predicate': 'PartOf', 'target': '2ndArchMesenchyme'}, {'predicate': 'PartOf', 'target': 'MesenchymeFromRhombencephalicNeuralCrest'}, {'predicate': 'DevelopsFrom', 'target': 'HyoidNeuralCrest'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": "A groove that is situated between the 2nd and 3rd pharyngeal arch.",
"id": "2ndArchPharyngealCleft",
"label": "2nd arch pharyngeal cleft",
"logical_definition": null,
"original_id": "UBERON:0005873",
"relationships": null
} | 0 | {
"document": "2nd arch pharyngeal cleft A groove that is situated between the 2nd and 3rd pharyngeal arch. None"
} |
{
"aliases": null,
"definition": "The anion resulting from the removal of the proton from the carboxylic acid group of 3,3',5-triiodo-L-thyronine.",
"id": "33_5TriiodoLThyroninate",
"label": "3,3',5-triiodo-L-thyroninate",
"logical_definition": null,
"original_id": "CHEBI:60308",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "33_5TriiodoLThyronine"
},
{
"predicate": "subClassOf",
"target": "AlphaAminoAcidAnion"
},
{
"predicate": "subClassOf",
"target": "MonocarboxylicAcidAnion"
},
{
"predicate": "subClassOf",
"target": "Iodothyroninate"
}
]
} | 0 | {
"document": "3,3',5-triiodo-L-thyroninate The anion resulting from the removal of the proton from the carboxylic acid group of 3,3',5-triiodo-L-thyronine. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '33_5TriiodoLThyronine'}, {'predicate': 'subClassOf', 'target': 'AlphaAminoAcidAnion'}, {'predicate': 'subClassOf', 'target': 'MonocarboxylicAcidAnion'}, {'predicate': 'subClassOf', 'target': 'Iodothyroninate'}]"
} |
{
"aliases": null,
"definition": "An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism.",
"id": "33_5TriiodoLThyronine",
"label": "3,3',5-triiodo-L-thyronine",
"logical_definition": null,
"original_id": "CHEBI:18258",
"relationships": [
{
"predicate": "HasRole",
"target": "ThyroidHormone"
},
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "33_5TriiodoLThyroninate"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "33_5TriiodoLThyronineZwitterion"
},
{
"predicate": "subClassOf",
"target": "Iodophenol"
},
{
"predicate": "subClassOf",
"target": "Iodothyronine"
},
{
"predicate": "subClassOf",
"target": "2Halophenol"
}
]
} | 0 | {
"document": "3,3',5-triiodo-L-thyronine An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism. [{'predicate': 'HasRole', 'target': 'ThyroidHormone'}, {'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '33_5TriiodoLThyroninate'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '33_5TriiodoLThyronineZwitterion'}, {'predicate': 'subClassOf', 'target': 'Iodophenol'}, {'predicate': 'subClassOf', 'target': 'Iodothyronine'}, {'predicate': 'subClassOf', 'target': '2Halophenol'}]"
} |
{
"aliases": null,
"definition": "The amino acid zwitterion formed from 3,3',5-triiodo-L-thyronine by tranfer of a proton from the carboxy group to the amino group. It is the major species at pH 7.3.",
"id": "33_5TriiodoLThyronineZwitterion",
"label": "3,3',5-triiodo-L-thyronine zwitterion",
"logical_definition": null,
"original_id": "CHEBI:533015",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "33_5TriiodoLThyronine"
},
{
"predicate": "subClassOf",
"target": "AminoAcidZwitterion"
}
]
} | 0 | {
"document": "3,3',5-triiodo-L-thyronine zwitterion The amino acid zwitterion formed from 3,3',5-triiodo-L-thyronine by tranfer of a proton from the carboxy group to the amino group. It is the major species at pH 7.3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '33_5TriiodoLThyronine'}, {'predicate': 'subClassOf', 'target': 'AminoAcidZwitterion'}]"
} |
{
"aliases": null,
"definition": "A soft tissue continuity in the A/P axis between fingers 3 and 4.",
"id": "34FingerCutaneousSyndactyly",
"label": "3-4 finger cutaneous syndactyly",
"logical_definition": null,
"original_id": "HP:0011939",
"relationships": [
{
"predicate": "subClassOf",
"target": "CutaneousFingerSyndactyly"
}
]
} | 0 | {
"document": "3-4 finger cutaneous syndactyly A soft tissue continuity in the A/P axis between fingers 3 and 4. [{'predicate': 'subClassOf', 'target': 'CutaneousFingerSyndactyly'}]"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of fingers three and four.",
"id": "34FingerSyndactyly",
"label": "3-4 finger syndactyly",
"logical_definition": null,
"original_id": "HP:0006097",
"relationships": [
{
"predicate": "subClassOf",
"target": "FingerSyndactyly"
}
]
} | 0 | {
"document": "3-4 finger syndactyly Syndactyly with fusion of fingers three and four. [{'predicate': 'subClassOf', 'target': 'FingerSyndactyly'}]"
} |
{
"aliases": null,
"definition": "A congenital hand malformation characterized by the coalescence of the coalescence of third and fourth metacarpals (i.e., those corresponding to the middle and ring fingers).",
"id": "34MetacarpalSynostosis",
"label": "3-4 metacarpal synostosis",
"logical_definition": null,
"original_id": "HP:4000062",
"relationships": [
{
"predicate": "subClassOf",
"target": "SynostosisInvolvingThe3rdMetacarpal"
},
{
"predicate": "subClassOf",
"target": "SynostosisInvolvingThe4thMetacarpal"
}
]
} | 0 | {
"document": "3-4 metacarpal synostosis A congenital hand malformation characterized by the coalescence of the coalescence of third and fourth metacarpals (i.e., those corresponding to the middle and ring fingers). [{'predicate': 'subClassOf', 'target': 'SynostosisInvolvingThe3rdMetacarpal'}, {'predicate': 'subClassOf', 'target': 'SynostosisInvolvingThe4thMetacarpal'}]"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of toes three and four.",
"id": "34ToeSyndactyly",
"label": "3-4 toe syndactyly",
"logical_definition": null,
"original_id": "HP:0009779",
"relationships": [
{
"predicate": "subClassOf",
"target": "ToeSyndactyly"
}
]
} | 0 | {
"document": "3-4 toe syndactyly Syndactyly with fusion of toes three and four. [{'predicate': 'subClassOf', 'target': 'ToeSyndactyly'}]"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of fingers three to five.",
"id": "35FingerSyndactyly",
"label": "3-5 finger syndactyly",
"logical_definition": null,
"original_id": "HP:0010710",
"relationships": [
{
"predicate": "subClassOf",
"target": "FingerSyndactyly"
}
]
} | 0 | {
"document": "3-5 finger syndactyly Syndactyly with fusion of fingers three to five. [{'predicate': 'subClassOf', 'target': 'FingerSyndactyly'}]"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of toes three to five.",
"id": "35ToeSyndactyly",
"label": "3-5 toe syndactyly",
"logical_definition": null,
"original_id": "HP:0010716",
"relationships": [
{
"predicate": "subClassOf",
"target": "ToeSyndactyly"
}
]
} | 0 | {
"document": "3-5 toe syndactyly Syndactyly with fusion of toes three to five. [{'predicate': 'subClassOf', 'target': 'ToeSyndactyly'}]"
} |
{
"aliases": null,
"definition": null,
"id": "3Amino3OxopropylGroup",
"label": "3-amino-3-oxopropyl group",
"logical_definition": null,
"original_id": "CHEBI:50331",
"relationships": [
{
"predicate": "subClassOf",
"target": "ProteinogenicAminoAcidSideChainGroup"
}
]
} | 0 | {
"document": "3-amino-3-oxopropyl group None [{'predicate': 'subClassOf', 'target': 'ProteinogenicAminoAcidSideChainGroup'}]"
} |
{
"aliases": null,
"definition": "Zwitterionic form of 3-aminoisobutyric acid arising from migration of a proton from the carboxy group to the amino group; major species at pH 7.3.",
"id": "3AminoisobutanoicAcidZwitterion",
"label": "3-aminoisobutanoic acid zwitterion",
"logical_definition": null,
"original_id": "CHEBI:142590",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3Aminoisobutyrate"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "3AminoisobutyricAcid"
},
{
"predicate": "subClassOf",
"target": "AminoAcidZwitterion"
}
]
} | 0 | {
"document": "3-aminoisobutanoic acid zwitterion Zwitterionic form of 3-aminoisobutyric acid arising from migration of a proton from the carboxy group to the amino group; major species at pH 7.3. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3Aminoisobutyrate'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '3AminoisobutyricAcid'}, {'predicate': 'subClassOf', 'target': 'AminoAcidZwitterion'}]"
} |
{
"aliases": null,
"definition": "A beta-amino acid anion that is the conjugate base of 3-aminoisobutyric acid, arising from deprotonation of the carboxy group.",
"id": "3Aminoisobutyrate",
"label": "3-aminoisobutyrate",
"logical_definition": null,
"original_id": "CHEBI:49096",
"relationships": [
{
"predicate": "HasRole",
"target": "Metabolite"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3AminoisobutanoicAcidZwitterion"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3AminoisobutyricAcid"
},
{
"predicate": "subClassOf",
"target": "BetaAminoAcidAnion"
}
]
} | 0 | {
"document": "3-aminoisobutyrate A beta-amino acid anion that is the conjugate base of 3-aminoisobutyric acid, arising from deprotonation of the carboxy group. [{'predicate': 'HasRole', 'target': 'Metabolite'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3AminoisobutanoicAcidZwitterion'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3AminoisobutyricAcid'}, {'predicate': 'subClassOf', 'target': 'BetaAminoAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A beta-amino-acid that is isobutyric acid in which one of the methyl hydrogens is substituted by an amino group.",
"id": "3AminoisobutyricAcid",
"label": "3-aminoisobutyric acid",
"logical_definition": null,
"original_id": "CHEBI:27389",
"relationships": [
{
"predicate": "HasRole",
"target": "Metabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "IsobutyricAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3Aminoisobutyrate"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "3AminoisobutanoicAcidZwitterion"
},
{
"predicate": "subClassOf",
"target": "BetaAminoAcid"
}
]
} | 0 | {
"document": "3-aminoisobutyric acid A beta-amino-acid that is isobutyric acid in which one of the methyl hydrogens is substituted by an amino group. [{'predicate': 'HasRole', 'target': 'Metabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'IsobutyricAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3Aminoisobutyrate'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '3AminoisobutanoicAcidZwitterion'}, {'predicate': 'subClassOf', 'target': 'BetaAminoAcid'}]"
} |
{
"aliases": null,
"definition": null,
"id": "3CarbamimidamidopropylGroup",
"label": "3-carbamimidamidopropyl group",
"logical_definition": null,
"original_id": "CHEBI:50340",
"relationships": [
{
"predicate": "subClassOf",
"target": "ProteinogenicAminoAcidSideChainGroup"
}
]
} | 0 | {
"document": "3-carbamimidamidopropyl group None [{'predicate': 'subClassOf', 'target': 'ProteinogenicAminoAcidSideChainGroup'}]"
} |
{
"aliases": null,
"definition": "A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions.",
"id": "3DExtent",
"label": "3-D extent",
"logical_definition": null,
"original_id": "PATO:0001710",
"relationships": [
{
"predicate": "subClassOf",
"target": "Size"
}
]
} | 0 | {
"document": "3-D extent A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions. [{'predicate': 'subClassOf', 'target': 'Size'}]"
} |
{
"aliases": null,
"definition": "A shape that inheres in a 3 dimensional entity.",
"id": "3DShape",
"label": "3-D shape",
"logical_definition": null,
"original_id": "PATO:0002266",
"relationships": [
{
"predicate": "subClassOf",
"target": "Shape"
}
]
} | 0 | {
"document": "3-D shape A shape that inheres in a 3 dimensional entity. [{'predicate': 'subClassOf', 'target': 'Shape'}]"
} |
{
"aliases": null,
"definition": "The 3H-tautomer of purine.",
"id": "3HPurine",
"label": "3H-purine",
"logical_definition": null,
"original_id": "CHEBI:35588",
"relationships": [
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "7HPurine"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "1HPurine"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "9HPurine"
},
{
"predicate": "subClassOf",
"target": "Purine"
}
]
} | 0 | {
"document": "3H-purine The 3H-tautomer of purine. [{'predicate': 'obo:chebi#is_tautomer_of', 'target': '7HPurine'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '1HPurine'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '9HPurine'}, {'predicate': 'subClassOf', 'target': 'Purine'}]"
} |
{
"aliases": null,
"definition": "A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid.",
"id": "3Hydroxy3Methylglutarate1_",
"label": "3-hydroxy-3-methylglutarate(1-)",
"logical_definition": null,
"original_id": "CHEBI:30920",
"relationships": [
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Glutarate1_"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3Hydroxy3Methylglutarate2_"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3Hydroxy3MethylglutaricAcid"
},
{
"predicate": "subClassOf",
"target": "DicarboxylicAcidMonoanion"
}
]
} | 0 | {
"document": "3-hydroxy-3-methylglutarate(1-) A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid. [{'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Glutarate1_'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3Hydroxy3Methylglutarate2_'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3Hydroxy3MethylglutaricAcid'}, {'predicate': 'subClassOf', 'target': 'DicarboxylicAcidMonoanion'}]"
} |
{
"aliases": null,
"definition": "A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid.",
"id": "3Hydroxy3Methylglutarate2_",
"label": "3-hydroxy-3-methylglutarate(2-)",
"logical_definition": null,
"original_id": "CHEBI:17325",
"relationships": [
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Glutarate2_"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3Hydroxy3Methylglutarate1_"
},
{
"predicate": "subClassOf",
"target": "3Hydroxydicarboxylate2_"
},
{
"predicate": "subClassOf",
"target": "DicarboxylicAcidDianion"
}
]
} | 0 | {
"document": "3-hydroxy-3-methylglutarate(2-) A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid. [{'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Glutarate2_'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3Hydroxy3Methylglutarate1_'}, {'predicate': 'subClassOf', 'target': '3Hydroxydicarboxylate2_'}, {'predicate': 'subClassOf', 'target': 'DicarboxylicAcidDianion'}]"
} |
{
"aliases": null,
"definition": "A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura.",
"id": "3Hydroxy3MethylglutaricAcid",
"label": "3-hydroxy-3-methylglutaric acid",
"logical_definition": null,
"original_id": "CHEBI:16831",
"relationships": [
{
"predicate": "HasRole",
"target": "Antimetabolite"
},
{
"predicate": "HasRole",
"target": "EC11134EC11188_hydroxymethylglutarylCoAReductase_inhibitor"
},
{
"predicate": "HasRole",
"target": "AnticholesteremicDrug"
},
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "GlutaricAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3Hydroxy3Methylglutarate1_"
},
{
"predicate": "subClassOf",
"target": "TertiaryAlcohol"
},
{
"predicate": "subClassOf",
"target": "DicarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "3HydroxyCarboxylicAcid"
}
]
} | 0 | {
"document": "3-hydroxy-3-methylglutaric acid A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura. [{'predicate': 'HasRole', 'target': 'Antimetabolite'}, {'predicate': 'HasRole', 'target': 'EC11134EC11188_hydroxymethylglutarylCoAReductase_inhibitor'}, {'predicate': 'HasRole', 'target': 'AnticholesteremicDrug'}, {'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'GlutaricAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3Hydroxy3Methylglutarate1_'}, {'predicate': 'subClassOf', 'target': 'TertiaryAlcohol'}, {'predicate': 'subClassOf', 'target': 'DicarboxylicAcid'}, {'predicate': 'subClassOf', 'target': '3HydroxyCarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group.",
"id": "3HydroxyCarboxylicAcid",
"label": "3-hydroxy carboxylic acid",
"logical_definition": null,
"original_id": "CHEBI:61355",
"relationships": [
{
"predicate": "subClassOf",
"target": "HydroxyCarboxylicAcid"
}
]
} | 0 | {
"document": "3-hydroxy carboxylic acid Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group. [{'predicate': 'subClassOf', 'target': 'HydroxyCarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "Any fatty acid with a hydroxy functional group in the beta- or 3-position. beta-Hydroxy fatty acids accumulate during cardiac hypoxia, and can also be used as chemical markers of bacterial endotoxins.",
"id": "3HydroxyFattyAcid",
"label": "3-hydroxy fatty acid",
"logical_definition": null,
"original_id": "CHEBI:59845",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3HydroxyFattyAcidAnion"
},
{
"predicate": "subClassOf",
"target": "HydroxyFattyAcid"
},
{
"predicate": "subClassOf",
"target": "3HydroxyMonocarboxylicAcid"
}
]
} | 0 | {
"document": "3-hydroxy fatty acid Any fatty acid with a hydroxy functional group in the beta- or 3-position. beta-Hydroxy fatty acids accumulate during cardiac hypoxia, and can also be used as chemical markers of bacterial endotoxins. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3HydroxyFattyAcidAnion'}, {'predicate': 'subClassOf', 'target': 'HydroxyFattyAcid'}, {'predicate': 'subClassOf', 'target': '3HydroxyMonocarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of any 3-hydroxy fatty acid.",
"id": "3HydroxyFattyAcidAnion",
"label": "3-hydroxy fatty acid anion",
"logical_definition": null,
"original_id": "CHEBI:84196",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3HydroxyFattyAcid"
},
{
"predicate": "subClassOf",
"target": "HydroxyFattyAcidAnion"
}
]
} | 0 | {
"document": "3-hydroxy fatty acid anion A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of any 3-hydroxy fatty acid. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3HydroxyFattyAcid'}, {'predicate': 'subClassOf', 'target': 'HydroxyFattyAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A hydroxy monocarboxylic acid that has a hydroxy group beta to the carboxy group.",
"id": "3HydroxyMonocarboxylicAcid",
"label": "3-hydroxy monocarboxylic acid",
"logical_definition": null,
"original_id": "CHEBI:35969",
"relationships": [
{
"predicate": "subClassOf",
"target": "HydroxyMonocarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "3HydroxyCarboxylicAcid"
}
]
} | 0 | {
"document": "3-hydroxy monocarboxylic acid A hydroxy monocarboxylic acid that has a hydroxy group beta to the carboxy group. [{'predicate': 'subClassOf', 'target': 'HydroxyMonocarboxylicAcid'}, {'predicate': 'subClassOf', 'target': '3HydroxyCarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "Any hydroxy steroid carrying a hydroxy group at position 3.",
"id": "3HydroxySteroid",
"label": "3-hydroxy steroid",
"logical_definition": null,
"original_id": "CHEBI:36834",
"relationships": [
{
"predicate": "subClassOf",
"target": "HydroxySteroid"
}
]
} | 0 | {
"document": "3-hydroxy steroid Any hydroxy steroid carrying a hydroxy group at position 3. [{'predicate': 'subClassOf', 'target': 'HydroxySteroid'}]"
} |
{
"aliases": null,
"definition": "Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.",
"id": "3HydroxyacylCoADehydrogenaseActivity",
"label": "3-hydroxyacyl-CoA dehydrogenase activity",
"logical_definition": null,
"original_id": "GO:0003857",
"relationships": [
{
"predicate": "subClassOf",
"target": "OxidoreductaseActivity_actingOnTheCHOHGroupOfDonors_NADOrNADPAsAcceptor"
}
]
} | 0 | {
"document": "3-hydroxyacyl-CoA dehydrogenase activity Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+. [{'predicate': 'subClassOf', 'target': 'OxidoreductaseActivity_actingOnTheCHOHGroupOfDonors_NADOrNADPAsAcceptor'}]"
} |
{
"aliases": null,
"definition": "A hydroxy fatty acid anion that is the conjugate base of 3-hydroxybutyric acid, obtained by deprotonation of the carboxy group; major species at pH 7.3.",
"id": "3Hydroxybutyrate",
"label": "3-hydroxybutyrate",
"logical_definition": null,
"original_id": "CHEBI:37054",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Butyrate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "3HydroxybutyricAcid"
},
{
"predicate": "subClassOf",
"target": "3HydroxyFattyAcidAnion"
}
]
} | 0 | {
"document": "3-hydroxybutyrate A hydroxy fatty acid anion that is the conjugate base of 3-hydroxybutyric acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Butyrate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '3HydroxybutyricAcid'}, {'predicate': 'subClassOf', 'target': '3HydroxyFattyAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.",
"id": "3HydroxybutyricAcid",
"label": "3-hydroxybutyric acid",
"logical_definition": null,
"original_id": "CHEBI:20067",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "ButyricAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3Hydroxybutyrate"
},
{
"predicate": "subClassOf",
"target": "HydroxybutyricAcid"
},
{
"predicate": "subClassOf",
"target": "3HydroxyMonocarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "_omega1_hydroxyFattyAcid"
}
]
} | 0 | {
"document": "3-hydroxybutyric acid A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'ButyricAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3Hydroxybutyrate'}, {'predicate': 'subClassOf', 'target': 'HydroxybutyricAcid'}, {'predicate': 'subClassOf', 'target': '3HydroxyMonocarboxylicAcid'}, {'predicate': 'subClassOf', 'target': '_omega1_hydroxyFattyAcid'}]"
} |
{
"aliases": null,
"definition": "A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of any 3-hydroxydicarboxylic acid.",
"id": "3Hydroxydicarboxylate2_",
"label": "3-hydroxydicarboxylate(2-)",
"logical_definition": null,
"original_id": "CHEBI:133251",
"relationships": [
{
"predicate": "subClassOf",
"target": "DicarboxylicAcidDianion"
}
]
} | 0 | {
"document": "3-hydroxydicarboxylate(2-) A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of any 3-hydroxydicarboxylic acid. [{'predicate': 'subClassOf', 'target': 'DicarboxylicAcidDianion'}]"
} |
{
"aliases": null,
"definition": "An increase in the level of 3-hydroxydicarboxylic acid in the urine.",
"id": "3HydroxydicarboxylicAciduria",
"label": "3-hydroxydicarboxylic aciduria",
"logical_definition": null,
"original_id": "HP:0008160",
"relationships": [
{
"predicate": "subClassOf",
"target": "DicarboxylicAciduria"
}
]
} | 0 | {
"document": "3-hydroxydicarboxylic aciduria An increase in the level of 3-hydroxydicarboxylic acid in the urine. [{'predicate': 'subClassOf', 'target': 'DicarboxylicAciduria'}]"
} |
{
"aliases": null,
"definition": "Concentration of 3-hydroxyisovaleric acid in the urine above the normal range.",
"id": "3HydroxyisovalericAciduria",
"label": "3-hydroxyisovaleric aciduria",
"logical_definition": null,
"original_id": "HP:0033111",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicAciduria"
}
]
} | 0 | {
"document": "3-hydroxyisovaleric aciduria Concentration of 3-hydroxyisovaleric acid in the urine above the normal range. [{'predicate': 'subClassOf', 'target': 'OrganicAciduria'}]"
} |
{
"aliases": null,
"definition": "A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 3-methyl fatty acid; major species at pH 7.3.",
"id": "3MethylFattyAcidAnion",
"label": "3-methyl fatty acid anion",
"logical_definition": null,
"original_id": "CHEBI:83972",
"relationships": [
{
"predicate": "subClassOf",
"target": "MethylBranchedFattyAcidAnion"
}
]
} | 0 | {
"document": "3-methyl fatty acid anion A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 3-methyl fatty acid; major species at pH 7.3. [{'predicate': 'subClassOf', 'target': 'MethylBranchedFattyAcidAnion'}]"
} |
{
"aliases": null,
"definition": "An increased amount of 3-methylglutaconic acid in the urine.",
"id": "3MethylglutaconicAciduria",
"label": "3-Methylglutaconic aciduria",
"logical_definition": null,
"original_id": "HP:0003535",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalUrineCarboxylicAcidLevel"
}
]
} | 0 | {
"document": "3-Methylglutaconic aciduria An increased amount of 3-methylglutaconic acid in the urine. [{'predicate': 'subClassOf', 'target': 'AbnormalUrineCarboxylicAcidLevel'}]"
} |
{
"aliases": null,
"definition": "An alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 3 by a methyl group.",
"id": "3MethylglutaricAcid",
"label": "3-methylglutaric acid",
"logical_definition": null,
"original_id": "CHEBI:68566",
"relationships": [
{
"predicate": "HasRole",
"target": "Metabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "GlutaricAcid"
},
{
"predicate": "subClassOf",
"target": "AlphaOmegaDicarboxylicAcid"
}
]
} | 0 | {
"document": "3-methylglutaric acid An alpha,omega-dicarboxylic acid that is glutaric acid substituted at position 3 by a methyl group. [{'predicate': 'HasRole', 'target': 'Metabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'GlutaricAcid'}, {'predicate': 'subClassOf', 'target': 'AlphaOmegaDicarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "An abnormally increased level of 3-hydroxy-3-methylglutaric acid in the urine.",
"id": "3MethylglutaricAciduria",
"label": "3-Methylglutaric aciduria",
"logical_definition": null,
"original_id": "HP:0003344",
"relationships": [
{
"predicate": "subClassOf",
"target": "AbnormalUrineCarboxylicAcidLevel"
}
]
} | 0 | {
"document": "3-Methylglutaric aciduria An abnormally increased level of 3-hydroxy-3-methylglutaric acid in the urine. [{'predicate': 'subClassOf', 'target': 'AbnormalUrineCarboxylicAcidLevel'}]"
} |
{
"aliases": null,
"definition": "A methylhistidine in which the methyl group is located at N-3.",
"id": "3Methylhistidine",
"label": "3-methylhistidine",
"logical_definition": null,
"original_id": "CHEBI:70959",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "3MethylhistidineZwitterion"
},
{
"predicate": "subClassOf",
"target": "Methylhistidine"
},
{
"predicate": "subClassOf",
"target": "NonProteinogenicAlphaAminoAcid"
}
]
} | 0 | {
"document": "3-methylhistidine A methylhistidine in which the methyl group is located at N-3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '3MethylhistidineZwitterion'}, {'predicate': 'subClassOf', 'target': 'Methylhistidine'}, {'predicate': 'subClassOf', 'target': 'NonProteinogenicAlphaAminoAcid'}]"
} |
{
"aliases": null,
"definition": "An alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 3-methylhistidine; major species at pH 7.3.",
"id": "3MethylhistidineZwitterion",
"label": "3-methylhistidine zwitterion",
"logical_definition": null,
"original_id": "CHEBI:133609",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "3Methylhistidine"
},
{
"predicate": "subClassOf",
"target": "AlphaAminoAcidZwitterion"
}
]
} | 0 | {
"document": "3-methylhistidine zwitterion An alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of 3-methylhistidine; major species at pH 7.3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '3Methylhistidine'}, {'predicate': 'subClassOf', 'target': 'AlphaAminoAcidZwitterion'}]"
} |
{
"aliases": null,
"definition": "A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position.",
"id": "3OxoDelta4_steroid",
"label": "3-oxo-Delta(4) steroid",
"logical_definition": null,
"original_id": "CHEBI:47909",
"relationships": [
{
"predicate": "HasPart",
"target": "3OxoDelta4_steroidGroup"
},
{
"predicate": "subClassOf",
"target": "3OxoSteroid"
},
{
"predicate": "subClassOf",
"target": "Enone"
}
]
} | 0 | {
"document": "3-oxo-Delta(4) steroid A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position. [{'predicate': 'HasPart', 'target': '3OxoDelta4_steroidGroup'}, {'predicate': 'subClassOf', 'target': '3OxoSteroid'}, {'predicate': 'subClassOf', 'target': 'Enone'}]"
} |
{
"aliases": null,
"definition": "An organic group derived from any 3-oxo-Delta(4)-steroid.",
"id": "3OxoDelta4_steroidGroup",
"label": "3-oxo-Delta(4)-steroid group",
"logical_definition": null,
"original_id": "CHEBI:136849",
"relationships": [
{
"predicate": "subClassOf",
"target": "OrganicGroup"
}
]
} | 0 | {
"document": "3-oxo-Delta(4)-steroid group An organic group derived from any 3-oxo-Delta(4)-steroid. [{'predicate': 'subClassOf', 'target': 'OrganicGroup'}]"
} |
{
"aliases": null,
"definition": "Any oxo steroid where an oxo substituent is located at position 3.",
"id": "3OxoSteroid",
"label": "3-oxo steroid",
"logical_definition": null,
"original_id": "CHEBI:47788",
"relationships": [
{
"predicate": "subClassOf",
"target": "OxoSteroid"
},
{
"predicate": "subClassOf",
"target": "CyclicKetone"
}
]
} | 0 | {
"document": "3-oxo steroid Any oxo steroid where an oxo substituent is located at position 3. [{'predicate': 'subClassOf', 'target': 'OxoSteroid'}, {'predicate': 'subClassOf', 'target': 'CyclicKetone'}]"
} |
{
"aliases": null,
"definition": "A 2-oxo monocarboxylic acid anion obtained by removal of a proton from the carboxylic acid group of 3-(4-hydroxyphenyl)pyruvic acid.",
"id": "3_4HydroxyphenylPyruvate",
"label": "3-(4-hydroxyphenyl)pyruvate",
"logical_definition": null,
"original_id": "CHEBI:36242",
"relationships": [
{
"predicate": "HasRole",
"target": "SaccharomycesCerevisiaeMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Pyruvate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "4HydroxyphenylpyruvicAcid"
},
{
"predicate": "subClassOf",
"target": "2OxoMonocarboxylicAcidAnion"
}
]
} | 0 | {
"document": "3-(4-hydroxyphenyl)pyruvate A 2-oxo monocarboxylic acid anion obtained by removal of a proton from the carboxylic acid group of 3-(4-hydroxyphenyl)pyruvic acid. [{'predicate': 'HasRole', 'target': 'SaccharomycesCerevisiaeMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Pyruvate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '4HydroxyphenylpyruvicAcid'}, {'predicate': 'subClassOf', 'target': '2OxoMonocarboxylicAcidAnion'}]"
} |
{
"aliases": null,
"definition": "Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6.",
"id": "3betaHydroxyDelta5_steroid",
"label": "3beta-hydroxy-Delta(5)-steroid",
"logical_definition": null,
"original_id": "CHEBI:1722",
"relationships": [
{
"predicate": "subClassOf",
"target": "3betaHydroxySteroid"
}
]
} | 0 | {
"document": "3beta-hydroxy-Delta(5)-steroid Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6. [{'predicate': 'subClassOf', 'target': '3betaHydroxySteroid'}]"
} |
{
"aliases": null,
"definition": "A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position.",
"id": "3betaHydroxySteroid",
"label": "3beta-hydroxy steroid",
"logical_definition": null,
"original_id": "CHEBI:36836",
"relationships": [
{
"predicate": "subClassOf",
"target": "SecondaryAlcohol"
},
{
"predicate": "subClassOf",
"target": "3HydroxySteroid"
}
]
} | 0 | {
"document": "3beta-hydroxy steroid A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position. [{'predicate': 'subClassOf', 'target': 'SecondaryAlcohol'}, {'predicate': 'subClassOf', 'target': '3HydroxySteroid'}]"
} |
{
"aliases": null,
"definition": "A sterol in which the hydroxy group at position 3 has beta- configuration.",
"id": "3betaSterol",
"label": "3beta-sterol",
"logical_definition": null,
"original_id": "CHEBI:35348",
"relationships": [
{
"predicate": "subClassOf",
"target": "Sterol"
},
{
"predicate": "subClassOf",
"target": "3betaHydroxySteroid"
}
]
} | 0 | {
"document": "3beta-sterol A sterol in which the hydroxy group at position 3 has beta- configuration. [{'predicate': 'subClassOf', 'target': 'Sterol'}, {'predicate': 'subClassOf', 'target': '3betaHydroxySteroid'}]"
} |
{
"aliases": null,
"definition": "An ectoderm that is part of a pharyngeal arch 3.",
"id": "3rdArchEctoderm",
"label": "3rd arch ectoderm",
"logical_definition": null,
"original_id": "UBERON:0005661",
"relationships": null
} | 0 | {
"document": "3rd arch ectoderm An ectoderm that is part of a pharyngeal arch 3. None"
} |
{
"aliases": null,
"definition": "An endoderm that is part of a pharyngeal arch 3.",
"id": "3rdArchEndoderm",
"label": "3rd arch endoderm",
"logical_definition": null,
"original_id": "UBERON:0005665",
"relationships": null
} | 0 | {
"document": "3rd arch endoderm An endoderm that is part of a pharyngeal arch 3. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that is part of a pharyngeal arch 3.",
"id": "3rdArchMesenchyme",
"label": "3rd arch mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0005690",
"relationships": null
} | 0 | {
"document": "3rd arch mesenchyme Mesenchyme that is part of a pharyngeal arch 3. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme.",
"id": "3rdArchMesenchymeFromHeadMesenchyme",
"label": "3rd arch mesenchyme from head mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0010344",
"relationships": [
{
"predicate": "PartOf",
"target": "3rdArchMesenchyme"
},
{
"predicate": "DevelopsFrom",
"target": "HeadMesenchymeFromMesoderm"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "3rd arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme. [{'predicate': 'PartOf', 'target': '3rdArchMesenchyme'}, {'predicate': 'DevelopsFrom', 'target': 'HeadMesenchymeFromMesoderm'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme.",
"id": "3rdArchMesenchymeFromNeuralCrest",
"label": "3rd arch mesenchyme from neural crest",
"logical_definition": null,
"original_id": "UBERON:0010255",
"relationships": [
{
"predicate": "PartOf",
"target": "3rdArchMesenchyme"
},
{
"predicate": "DevelopsFrom",
"target": "RhombencephalonNeuralCrest"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "3rd arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme. [{'predicate': 'PartOf', 'target': '3rdArchMesenchyme'}, {'predicate': 'DevelopsFrom', 'target': 'RhombencephalonNeuralCrest'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": "A groove that is situated between the 3rd and 4th pharyngeal arch.",
"id": "3rdArchPharyngealCleft",
"label": "3rd arch pharyngeal cleft",
"logical_definition": null,
"original_id": "UBERON:0005874",
"relationships": null
} | 0 | {
"document": "3rd arch pharyngeal cleft A groove that is situated between the 3rd and 4th pharyngeal arch. None"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of fingers four and five.",
"id": "45FingerSyndactyly",
"label": "4-5 finger syndactyly",
"logical_definition": null,
"original_id": "HP:0010705",
"relationships": [
{
"predicate": "subClassOf",
"target": "FingerSyndactyly"
}
]
} | 0 | {
"document": "4-5 finger syndactyly Syndactyly with fusion of fingers four and five. [{'predicate': 'subClassOf', 'target': 'FingerSyndactyly'}]"
} |
{
"aliases": null,
"definition": null,
"id": "45MetacarpalSynostosis",
"label": "4-5 metacarpal synostosis",
"logical_definition": null,
"original_id": "HP:0005867",
"relationships": [
{
"predicate": "subClassOf",
"target": "SynostosisInvolvingThe4thMetacarpal"
},
{
"predicate": "subClassOf",
"target": "SynostosisInvolvingThe5thMetacarpal"
}
]
} | 0 | {
"document": "4-5 metacarpal synostosis None [{'predicate': 'subClassOf', 'target': 'SynostosisInvolvingThe4thMetacarpal'}, {'predicate': 'subClassOf', 'target': 'SynostosisInvolvingThe5thMetacarpal'}]"
} |
{
"aliases": null,
"definition": "Syndactyly with fusion of toes four and five.",
"id": "45ToeSyndactyly",
"label": "4-5 toe syndactyly",
"logical_definition": null,
"original_id": "HP:0004692",
"relationships": [
{
"predicate": "subClassOf",
"target": "ToeSyndactyly"
}
]
} | 0 | {
"document": "4-5 toe syndactyly Syndactyly with fusion of toes four and five. [{'predicate': 'subClassOf', 'target': 'ToeSyndactyly'}]"
} |
{
"aliases": null,
"definition": "The conjugate base of gamma-amino-beta-hydroxybutyric acid arising from deprotonation of the carboxy group.",
"id": "4Amino3Hydroxybutanoate",
"label": "4-amino-3-hydroxybutanoate",
"logical_definition": null,
"original_id": "CHEBI:11955",
"relationships": [
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Butyrate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "GammaAminoBetaHydroxybutyricAcid"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "GammaAminoBetaHydroxybutyricAcidZwitterion"
},
{
"predicate": "subClassOf",
"target": "HydroxyMonocarboxylicAcidAnion"
},
{
"predicate": "subClassOf",
"target": "GammaAminoAcidAnion"
}
]
} | 0 | {
"document": "4-amino-3-hydroxybutanoate The conjugate base of gamma-amino-beta-hydroxybutyric acid arising from deprotonation of the carboxy group. [{'predicate': 'obo:chebi#has_functional_parent', 'target': 'Butyrate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'GammaAminoBetaHydroxybutyricAcid'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': 'GammaAminoBetaHydroxybutyricAcidZwitterion'}, {'predicate': 'subClassOf', 'target': 'HydroxyMonocarboxylicAcidAnion'}, {'predicate': 'subClassOf', 'target': 'GammaAminoAcidAnion'}]"
} |
{
"aliases": null,
"definition": null,
"id": "4AminobutylGroup",
"label": "4-aminobutyl group",
"logical_definition": null,
"original_id": "CHEBI:50339",
"relationships": [
{
"predicate": "obo:chebi#is_substituent_group_from",
"target": "Butan1Amine"
},
{
"predicate": "subClassOf",
"target": "ProteinogenicAminoAcidSideChainGroup"
}
]
} | 0 | {
"document": "4-aminobutyl group None [{'predicate': 'obo:chebi#is_substituent_group_from', 'target': 'Butan1Amine'}, {'predicate': 'subClassOf', 'target': 'ProteinogenicAminoAcidSideChainGroup'}]"
} |
{
"aliases": null,
"definition": "The D-stereoisomer of 4-hydroxyproline.",
"id": "4HydroxyDProline",
"label": "4-hydroxy-D-proline",
"logical_definition": null,
"original_id": "CHEBI:144637",
"relationships": [
{
"predicate": "obo:chebi#is_enantiomer_of",
"target": "4HydroxyLProline"
},
{
"predicate": "subClassOf",
"target": "4Hydroxyproline"
},
{
"predicate": "subClassOf",
"target": "DProlineDerivative"
}
]
} | 0 | {
"document": "4-hydroxy-D-proline The D-stereoisomer of 4-hydroxyproline. [{'predicate': 'obo:chebi#is_enantiomer_of', 'target': '4HydroxyLProline'}, {'predicate': 'subClassOf', 'target': '4Hydroxyproline'}, {'predicate': 'subClassOf', 'target': 'DProlineDerivative'}]"
} |
{
"aliases": null,
"definition": "The L-alpha-amino acid anion that is the conjugate base of 4-hydroxy-L-proline, formed by proton loss from the carboxy group. It is the major microspecies present at pH > 10.6.",
"id": "4HydroxyLProlinate",
"label": "4-hydroxy-L-prolinate",
"logical_definition": null,
"original_id": "CHEBI:62981",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "4HydroxyLProline"
},
{
"predicate": "subClassOf",
"target": "LAlphaAminoAcidAnion"
},
{
"predicate": "subClassOf",
"target": "4Hydroxyprolinate"
}
]
} | 0 | {
"document": "4-hydroxy-L-prolinate The L-alpha-amino acid anion that is the conjugate base of 4-hydroxy-L-proline, formed by proton loss from the carboxy group. It is the major microspecies present at pH > 10.6. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '4HydroxyLProline'}, {'predicate': 'subClassOf', 'target': 'LAlphaAminoAcidAnion'}, {'predicate': 'subClassOf', 'target': '4Hydroxyprolinate'}]"
} |
{
"aliases": null,
"definition": "The L-stereoisomer of 4-hydroxyproline.",
"id": "4HydroxyLProline",
"label": "4-hydroxy-L-proline",
"logical_definition": null,
"original_id": "CHEBI:18240",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "4HydroxyLProlinate"
},
{
"predicate": "obo:chebi#is_enantiomer_of",
"target": "4HydroxyDProline"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "4HydroxyLProlineZwitterion"
},
{
"predicate": "subClassOf",
"target": "4Hydroxyproline"
},
{
"predicate": "subClassOf",
"target": "NonProteinogenicLAlphaAminoAcid"
},
{
"predicate": "subClassOf",
"target": "LProlineDerivative"
}
]
} | 0 | {
"document": "4-hydroxy-L-proline The L-stereoisomer of 4-hydroxyproline. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '4HydroxyLProlinate'}, {'predicate': 'obo:chebi#is_enantiomer_of', 'target': '4HydroxyDProline'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '4HydroxyLProlineZwitterion'}, {'predicate': 'subClassOf', 'target': '4Hydroxyproline'}, {'predicate': 'subClassOf', 'target': 'NonProteinogenicLAlphaAminoAcid'}, {'predicate': 'subClassOf', 'target': 'LProlineDerivative'}]"
} |
{
"aliases": null,
"definition": "The amino acid zwitterion formed from 4-hydroxy-L-proline. It is the major microspecies present at pH 7.3.",
"id": "4HydroxyLProlineZwitterion",
"label": "4-hydroxy-L-proline zwitterion",
"logical_definition": null,
"original_id": "CHEBI:58419",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "4HydroxyLProline"
},
{
"predicate": "subClassOf",
"target": "4HydroxyprolineZwitterion"
}
]
} | 0 | {
"document": "4-hydroxy-L-proline zwitterion The amino acid zwitterion formed from 4-hydroxy-L-proline. It is the major microspecies present at pH 7.3. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '4HydroxyLProline'}, {'predicate': 'subClassOf', 'target': '4HydroxyprolineZwitterion'}]"
} |
{
"aliases": null,
"definition": null,
"id": "4HydroxybenzylGroup",
"label": "4-hydroxybenzyl group",
"logical_definition": null,
"original_id": "CHEBI:50336",
"relationships": [
{
"predicate": "subClassOf",
"target": "ProteinogenicAminoAcidSideChainGroup"
}
]
} | 0 | {
"document": "4-hydroxybenzyl group None [{'predicate': 'subClassOf', 'target': 'ProteinogenicAminoAcidSideChainGroup'}]"
} |
{
"aliases": null,
"definition": "A monocarboxylic acid anion that is obtained by removal of a proton from the carboxylic acid group of 4-hydroxyphenylacetic acid.",
"id": "4Hydroxyphenylacetate",
"label": "4-hydroxyphenylacetate",
"logical_definition": null,
"original_id": "CHEBI:48999",
"relationships": [
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "FungalMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "Acetate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "4HydroxyphenylaceticAcid"
},
{
"predicate": "subClassOf",
"target": "MonocarboxylicAcidAnion"
}
]
} | 0 | {
"document": "4-hydroxyphenylacetate A monocarboxylic acid anion that is obtained by removal of a proton from the carboxylic acid group of 4-hydroxyphenylacetic acid. [{'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'FungalMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'Acetate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '4HydroxyphenylaceticAcid'}, {'predicate': 'subClassOf', 'target': 'MonocarboxylicAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group.",
"id": "4HydroxyphenylaceticAcid",
"label": "4-hydroxyphenylacetic acid",
"logical_definition": null,
"original_id": "CHEBI:18101",
"relationships": [
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "FungalMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "AceticAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "4Hydroxyphenylacetate"
},
{
"predicate": "subClassOf",
"target": "MonocarboxylicAcid"
},
{
"predicate": "subClassOf",
"target": "Phenols"
}
]
} | 0 | {
"document": "4-hydroxyphenylacetic acid A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. [{'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'FungalMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'AceticAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '4Hydroxyphenylacetate'}, {'predicate': 'subClassOf', 'target': 'MonocarboxylicAcid'}, {'predicate': 'subClassOf', 'target': 'Phenols'}]"
} |
{
"aliases": null,
"definition": "Increased concentration of 4-hydroxyphenylacetic acid in the urine.",
"id": "4HydroxyphenylaceticAciduria",
"label": "4-hydroxyphenylacetic aciduria",
"logical_definition": null,
"original_id": "HP:0003607",
"relationships": [
{
"predicate": "subClassOf",
"target": "ElevatedUrinaryCarboxylicAcid"
}
]
} | 0 | {
"document": "4-hydroxyphenylacetic aciduria Increased concentration of 4-hydroxyphenylacetic acid in the urine. [{'predicate': 'subClassOf', 'target': 'ElevatedUrinaryCarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "A protein that is a translation product of the human HPD gene or a 1:1 ortholog thereof.",
"id": "4HydroxyphenylpyruvateDioxygenase",
"label": "4-hydroxyphenylpyruvate dioxygenase",
"logical_definition": null,
"original_id": "PR:000008730",
"relationships": [
{
"predicate": "subClassOf",
"target": "Protein_PR:000000001"
}
]
} | 0 | {
"document": "4-hydroxyphenylpyruvate dioxygenase A protein that is a translation product of the human HPD gene or a 1:1 ortholog thereof. [{'predicate': 'subClassOf', 'target': 'Protein_PR:000000001'}]"
} |
{
"aliases": null,
"definition": "A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of human.",
"id": "4HydroxyphenylpyruvateDioxygenase_human_",
"label": "4-hydroxyphenylpyruvate dioxygenase (human)",
"logical_definition": null,
"original_id": "PR:P32754",
"relationships": [
{
"predicate": "subClassOf",
"target": "4HydroxyphenylpyruvateDioxygenase"
},
{
"predicate": "subClassOf",
"target": "HomoSapiensProtein"
}
]
} | 0 | {
"document": "4-hydroxyphenylpyruvate dioxygenase (human) A 4-hydroxyphenylpyruvate dioxygenase that is encoded in the genome of human. [{'predicate': 'subClassOf', 'target': '4HydroxyphenylpyruvateDioxygenase'}, {'predicate': 'subClassOf', 'target': 'HomoSapiensProtein'}]"
} |
{
"aliases": null,
"definition": "A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group.",
"id": "4HydroxyphenylpyruvicAcid",
"label": "4-hydroxyphenylpyruvic acid",
"logical_definition": null,
"original_id": "CHEBI:15999",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "PyruvicAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "3_4HydroxyphenylPyruvate"
},
{
"predicate": "subClassOf",
"target": "Phenols"
},
{
"predicate": "subClassOf",
"target": "2OxoMonocarboxylicAcid"
}
]
} | 0 | {
"document": "4-hydroxyphenylpyruvic acid A 2-oxo monocarboxylic acid that is pyruvic acid in which one of the methyl hydrogens is substituted by a 4-hydroxyphenyl group. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': 'PyruvicAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '3_4HydroxyphenylPyruvate'}, {'predicate': 'subClassOf', 'target': 'Phenols'}, {'predicate': 'subClassOf', 'target': '2OxoMonocarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "Increased relative concentration of 4-hydroxyphenylpyruvic acid in the urine.",
"id": "4HydroxyphenylpyruvicAciduria",
"label": "4-Hydroxyphenylpyruvic aciduria",
"logical_definition": null,
"original_id": "HP:0003161",
"relationships": [
{
"predicate": "subClassOf",
"target": "ElevatedUrinaryCarboxylicAcid"
}
]
} | 0 | {
"document": "4-Hydroxyphenylpyruvic aciduria Increased relative concentration of 4-hydroxyphenylpyruvic acid in the urine. [{'predicate': 'subClassOf', 'target': 'ElevatedUrinaryCarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "The alpha-amino-acid anion formed by loss of a proton from the carboxy group of 4-hydroxyproline.",
"id": "4Hydroxyprolinate",
"label": "4-hydroxyprolinate",
"logical_definition": null,
"original_id": "CHEBI:62978",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "4Hydroxyproline"
},
{
"predicate": "subClassOf",
"target": "AlphaAminoAcidAnion"
}
]
} | 0 | {
"document": "4-hydroxyprolinate The alpha-amino-acid anion formed by loss of a proton from the carboxy group of 4-hydroxyproline. [{'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '4Hydroxyproline'}, {'predicate': 'subClassOf', 'target': 'AlphaAminoAcidAnion'}]"
} |
{
"aliases": null,
"definition": "A monohydroxyproline where the hydroxy group is located at the 4-position. It is found in fibrillar collagen.",
"id": "4Hydroxyproline",
"label": "4-hydroxyproline",
"logical_definition": null,
"original_id": "CHEBI:20392",
"relationships": [
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "4Hydroxyprolinate"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "4HydroxyprolineZwitterion"
},
{
"predicate": "subClassOf",
"target": "Monohydroxyproline"
}
]
} | 0 | {
"document": "4-hydroxyproline A monohydroxyproline where the hydroxy group is located at the 4-position. It is found in fibrillar collagen. [{'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '4Hydroxyprolinate'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '4HydroxyprolineZwitterion'}, {'predicate': 'subClassOf', 'target': 'Monohydroxyproline'}]"
} |
{
"aliases": null,
"definition": "The amino acid zwitterion formed from 4-hydroxyproline.",
"id": "4HydroxyprolineZwitterion",
"label": "4-hydroxyproline zwitterion",
"logical_definition": null,
"original_id": "CHEBI:63137",
"relationships": [
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "4Hydroxyproline"
},
{
"predicate": "subClassOf",
"target": "AminoAcidZwitterion"
}
]
} | 0 | {
"document": "4-hydroxyproline zwitterion The amino acid zwitterion formed from 4-hydroxyproline. [{'predicate': 'obo:chebi#is_tautomer_of', 'target': '4Hydroxyproline'}, {'predicate': 'subClassOf', 'target': 'AminoAcidZwitterion'}]"
} |
{
"aliases": null,
"definition": "A form of lissencephaly in which the cortex is thickened and has four more or less disorganized layers rather than six normal layers resulting from incomplete neuronal migration during brain development. At neuropathological examination, a 4-layered cortex consists of an upper molecular layer, a second thin cellular layer containing pyramidal neurons usually observed in layer V, a third pale poorly cellular layer and a fourth thick deep layer made up of neurons which had failed to migrate. Radiologocally would manifest as agyria or pachygyria with cortical thickness greater than 10 mm.",
"id": "4LayeredLissencephaly",
"label": "4-layered lissencephaly",
"logical_definition": null,
"original_id": "HP:0006818",
"relationships": [
{
"predicate": "subClassOf",
"target": "Lissencephaly"
}
]
} | 0 | {
"document": "4-layered lissencephaly A form of lissencephaly in which the cortex is thickened and has four more or less disorganized layers rather than six normal layers resulting from incomplete neuronal migration during brain development. At neuropathological examination, a 4-layered cortex consists of an upper molecular layer, a second thin cellular layer containing pyramidal neurons usually observed in layer V, a third pale poorly cellular layer and a fourth thick deep layer made up of neurons which had failed to migrate. Radiologocally would manifest as agyria or pachygyria with cortical thickness greater than 10 mm. [{'predicate': 'subClassOf', 'target': 'Lissencephaly'}]"
} |
{
"aliases": null,
"definition": null,
"id": "4OxoMonocarboxylicAcid",
"label": "4-oxo monocarboxylic acid",
"logical_definition": null,
"original_id": "CHEBI:35950",
"relationships": [
{
"predicate": "subClassOf",
"target": "OxoMonocarboxylicAcid"
}
]
} | 0 | {
"document": "4-oxo monocarboxylic acid None [{'predicate': 'subClassOf', 'target': 'OxoMonocarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "A member of the class of oxopentanoates that is the conjugate base of 4-oxopentanoic acid.",
"id": "4Oxopentanoate",
"label": "4-oxopentanoate",
"logical_definition": null,
"original_id": "CHEBI:39150",
"relationships": [
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "4OxopentanoicAcid"
},
{
"predicate": "subClassOf",
"target": "Oxopentanoates"
}
]
} | 0 | {
"document": "4-oxopentanoate A member of the class of oxopentanoates that is the conjugate base of 4-oxopentanoic acid. [{'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '4OxopentanoicAcid'}, {'predicate': 'subClassOf', 'target': 'Oxopentanoates'}]"
} |
{
"aliases": null,
"definition": "An oxopentanoic acid with the oxo group in the 4-position.",
"id": "4OxopentanoicAcid",
"label": "4-oxopentanoic acid",
"logical_definition": null,
"original_id": "CHEBI:45630",
"relationships": [
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "4Oxopentanoate"
},
{
"predicate": "subClassOf",
"target": "OxopentanoicAcid"
},
{
"predicate": "subClassOf",
"target": "StraightChainSaturatedFattyAcid"
}
]
} | 0 | {
"document": "4-oxopentanoic acid An oxopentanoic acid with the oxo group in the 4-position. [{'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '4Oxopentanoate'}, {'predicate': 'subClassOf', 'target': 'OxopentanoicAcid'}, {'predicate': 'subClassOf', 'target': 'StraightChainSaturatedFattyAcid'}]"
} |
{
"aliases": null,
"definition": "A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen.",
"id": "4_1Hydroxy2_methylaminoEthylBenzene12Diol",
"label": "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol",
"logical_definition": null,
"original_id": "CHEBI:194548",
"relationships": [
{
"predicate": "subClassOf",
"target": "Catecholamine"
}
]
} | 0 | {
"document": "4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol A catecholamine in which the aminoethyl side-chain is hydroxy-substituted at C-1 and methylated on nitrogen. [{'predicate': 'subClassOf', 'target': 'Catecholamine'}]"
} |
{
"aliases": null,
"definition": "An ectoderm that is part of a pharyngeal arch 4.",
"id": "4thArchEctoderm",
"label": "4th arch ectoderm",
"logical_definition": null,
"original_id": "UBERON:0005662",
"relationships": null
} | 0 | {
"document": "4th arch ectoderm An ectoderm that is part of a pharyngeal arch 4. None"
} |
{
"aliases": null,
"definition": "An endoderm that is part of a pharyngeal arch 4.",
"id": "4thArchEndoderm",
"label": "4th arch endoderm",
"logical_definition": null,
"original_id": "UBERON:0005666",
"relationships": null
} | 0 | {
"document": "4th arch endoderm An endoderm that is part of a pharyngeal arch 4. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that is part of a pharyngeal arch 4.",
"id": "4thArchMesenchyme",
"label": "4th arch mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0005691",
"relationships": null
} | 0 | {
"document": "4th arch mesenchyme Mesenchyme that is part of a pharyngeal arch 4. None"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme.",
"id": "4thArchMesenchymeFromHeadMesenchyme",
"label": "4th arch mesenchyme from head mesenchyme",
"logical_definition": null,
"original_id": "UBERON:0010345",
"relationships": [
{
"predicate": "PartOf",
"target": "4thArchMesenchyme"
},
{
"predicate": "DevelopsFrom",
"target": "HeadMesenchymeFromMesoderm"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "4th arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. [{'predicate': 'PartOf', 'target': '4thArchMesenchyme'}, {'predicate': 'DevelopsFrom', 'target': 'HeadMesenchymeFromMesoderm'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": "Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme.",
"id": "4thArchMesenchymeFromNeuralCrest",
"label": "4th arch mesenchyme from neural crest",
"logical_definition": null,
"original_id": "UBERON:0010256",
"relationships": [
{
"predicate": "PartOf",
"target": "4thArchMesenchyme"
},
{
"predicate": "PartOf",
"target": "MesenchymeFromRhombencephalicNeuralCrest"
},
{
"predicate": "DevelopsFrom",
"target": "RhombencephalonNeuralCrest"
},
{
"predicate": "subClassOf",
"target": "DenseMesenchymeTissue"
}
]
} | 0 | {
"document": "4th arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. [{'predicate': 'PartOf', 'target': '4thArchMesenchyme'}, {'predicate': 'PartOf', 'target': 'MesenchymeFromRhombencephalicNeuralCrest'}, {'predicate': 'DevelopsFrom', 'target': 'RhombencephalonNeuralCrest'}, {'predicate': 'subClassOf', 'target': 'DenseMesenchymeTissue'}]"
} |
{
"aliases": null,
"definition": null,
"id": "5Aminolevulinate",
"label": "5-aminolevulinate",
"logical_definition": null,
"original_id": "CHEBI:12109",
"relationships": [
{
"predicate": "obo:chebi#has_functional_parent",
"target": "4Oxopentanoate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "5AminolevulinicAcid"
},
{
"predicate": "subClassOf",
"target": "MonocarboxylicAcidAnion"
}
]
} | 0 | {
"document": "5-aminolevulinate None [{'predicate': 'obo:chebi#has_functional_parent', 'target': '4Oxopentanoate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '5AminolevulinicAcid'}, {'predicate': 'subClassOf', 'target': 'MonocarboxylicAcidAnion'}]"
} |
{
"aliases": null,
"definition": "The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.",
"id": "5AminolevulinicAcid",
"label": "5-aminolevulinic acid",
"logical_definition": null,
"original_id": "CHEBI:17549",
"relationships": [
{
"predicate": "HasRole",
"target": "AntineoplasticAgent"
},
{
"predicate": "HasRole",
"target": "PhotosensitizingAgent"
},
{
"predicate": "HasRole",
"target": "DermatologicDrug"
},
{
"predicate": "HasRole",
"target": "Prodrug"
},
{
"predicate": "HasRole",
"target": "MouseMetabolite"
},
{
"predicate": "HasRole",
"target": "SaccharomycesCerevisiaeMetabolite"
},
{
"predicate": "HasRole",
"target": "PlantMetabolite"
},
{
"predicate": "HasRole",
"target": "EscherichiaColiMetabolite"
},
{
"predicate": "HasRole",
"target": "HumanMetabolite"
},
{
"predicate": "obo:chebi#has_functional_parent",
"target": "4OxopentanoicAcid"
},
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "5Aminolevulinate"
},
{
"predicate": "obo:chebi#is_conjugate_base_of",
"target": "5AmmoniolevulinicAcid"
},
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "5Ammoniolevulinate"
},
{
"predicate": "subClassOf",
"target": "DeltaAminoAcid"
},
{
"predicate": "subClassOf",
"target": "4OxoMonocarboxylicAcid"
}
]
} | 0 | {
"document": "5-aminolevulinic acid The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp. [{'predicate': 'HasRole', 'target': 'AntineoplasticAgent'}, {'predicate': 'HasRole', 'target': 'PhotosensitizingAgent'}, {'predicate': 'HasRole', 'target': 'DermatologicDrug'}, {'predicate': 'HasRole', 'target': 'Prodrug'}, {'predicate': 'HasRole', 'target': 'MouseMetabolite'}, {'predicate': 'HasRole', 'target': 'SaccharomycesCerevisiaeMetabolite'}, {'predicate': 'HasRole', 'target': 'PlantMetabolite'}, {'predicate': 'HasRole', 'target': 'EscherichiaColiMetabolite'}, {'predicate': 'HasRole', 'target': 'HumanMetabolite'}, {'predicate': 'obo:chebi#has_functional_parent', 'target': '4OxopentanoicAcid'}, {'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '5Aminolevulinate'}, {'predicate': 'obo:chebi#is_conjugate_base_of', 'target': '5AmmoniolevulinicAcid'}, {'predicate': 'obo:chebi#is_tautomer_of', 'target': '5Ammoniolevulinate'}, {'predicate': 'subClassOf', 'target': 'DeltaAminoAcid'}, {'predicate': 'subClassOf', 'target': '4OxoMonocarboxylicAcid'}]"
} |
{
"aliases": null,
"definition": "The zwitterion formed from 5-aminolevulinic acid by transfer of a proton from the carboxy group to the amino group. It is the major species present at physiological pH.",
"id": "5Ammoniolevulinate",
"label": "5-ammoniolevulinate",
"logical_definition": null,
"original_id": "CHEBI:356416",
"relationships": [
{
"predicate": "obo:chebi#is_tautomer_of",
"target": "5AminolevulinicAcid"
},
{
"predicate": "subClassOf",
"target": "AminoAcidZwitterion"
}
]
} | 0 | {
"document": "5-ammoniolevulinate The zwitterion formed from 5-aminolevulinic acid by transfer of a proton from the carboxy group to the amino group. It is the major species present at physiological pH. [{'predicate': 'obo:chebi#is_tautomer_of', 'target': '5AminolevulinicAcid'}, {'predicate': 'subClassOf', 'target': 'AminoAcidZwitterion'}]"
} |
{
"aliases": null,
"definition": "A primary ammonium ion obtained by protonation of the amino group of 5-aminolevulinic acid.",
"id": "5AmmoniolevulinicAcid",
"label": "5-ammoniolevulinic acid",
"logical_definition": null,
"original_id": "CHEBI:132970",
"relationships": [
{
"predicate": "obo:chebi#is_conjugate_acid_of",
"target": "5AminolevulinicAcid"
},
{
"predicate": "subClassOf",
"target": "PrimaryAmmoniumIon"
}
]
} | 0 | {
"document": "5-ammoniolevulinic acid A primary ammonium ion obtained by protonation of the amino group of 5-aminolevulinic acid. [{'predicate': 'obo:chebi#is_conjugate_acid_of', 'target': '5AminolevulinicAcid'}, {'predicate': 'subClassOf', 'target': 'PrimaryAmmoniumIon'}]"
} |
{
"aliases": null,
"definition": "History of having been treated with 5-fluorouracil.",
"id": "5FluorouracilExposure",
"label": "5-fluorouracil exposure",
"logical_definition": null,
"original_id": "HP:4000135",
"relationships": [
{
"predicate": "subClassOf",
"target": "MedicationHistory"
}
]
} | 0 | {
"document": "5-fluorouracil exposure History of having been treated with 5-fluorouracil. [{'predicate': 'subClassOf', 'target': 'MedicationHistory'}]"
} |