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b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Aspartate aminotransferase (AST)/Alanine aminotransferase (ALT) < or = 2.5X institutional upper limit of normal secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: More than three prior chemotherapy lines for advanced disease. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Symptomatic CNS metastases or evidence of leptomeningeal disease. Previously treated asymptomatic CNS metastases are allowed provided that the last treatment for CNS metastases was completed >8 weeks prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Peripheral neuropathy grade 2 at randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Active cardiac disease the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: History of cardiac dysfunction the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Any malignancy within 5 years prior to randomization, with the exception of adequately treated in-situ carcinoma of the cervix uteri, basal or squamous cell carcinoma or non-melanomatous skin cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Known hypersensitivity to any study medication the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: creatinine < or = 1.5 X institutional upper limit of normal secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: More than three prior chemotherapy lines for advanced disease. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Symptomatic CNS metastases or evidence of leptomeningeal disease. Previously treated asymptomatic CNS metastases are allowed provided that the last treatment for CNS metastases was completed >8 weeks prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Peripheral neuropathy grade 2 at randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Active cardiac disease the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: History of cardiac dysfunction the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Any malignancy within 5 years prior to randomization, with the exception of adequately treated in-situ carcinoma of the cervix uteri, basal or squamous cell carcinoma or non-melanomatous skin cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Known hypersensitivity to any study medication the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Informed consent. secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: More than three prior chemotherapy lines for advanced disease. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Symptomatic CNS metastases or evidence of leptomeningeal disease. Previously treated asymptomatic CNS metastases are allowed provided that the last treatment for CNS metastases was completed >8 weeks prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Peripheral neuropathy grade 2 at randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Active cardiac disease the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: History of cardiac dysfunction the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Any malignancy within 5 years prior to randomization, with the exception of adequately treated in-situ carcinoma of the cervix uteri, basal or squamous cell carcinoma or non-melanomatous skin cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Known hypersensitivity to any study medication the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Brain metastases unless resected or irradiated and stable > or = 8 weeks. secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: More than three prior chemotherapy lines for advanced disease. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Symptomatic CNS metastases or evidence of leptomeningeal disease. Previously treated asymptomatic CNS metastases are allowed provided that the last treatment for CNS metastases was completed >8 weeks prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Peripheral neuropathy grade 2 at randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Active cardiac disease the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: History of cardiac dysfunction the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Any malignancy within 5 years prior to randomization, with the exception of adequately treated in-situ carcinoma of the cervix uteri, basal or squamous cell carcinoma or non-melanomatous skin cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Known hypersensitivity to any study medication the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Treatment with other investigational agents. secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: More than three prior chemotherapy lines for advanced disease. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Symptomatic CNS metastases or evidence of leptomeningeal disease. Previously treated asymptomatic CNS metastases are allowed provided that the last treatment for CNS metastases was completed >8 weeks prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Impairment of gastrointestinal (GI) function or GI disease that may significantly alter the absorption of oral everolimus the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Peripheral neuropathy grade 2 at randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Active cardiac disease the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: History of cardiac dysfunction the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Any malignancy within 5 years prior to randomization, with the exception of adequately treated in-situ carcinoma of the cervix uteri, basal or squamous cell carcinoma or non-melanomatous skin cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Known hypersensitivity to any study medication the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received radiotherapy, high-potency corticosteroids, intralesional therapy, laser therapy or surgery other than biopsy to the target area within 4 weeks prior to first dosing of study agent. secondary trial: Breastfeeding or pregnant the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Histologically or cytologically confirmed invasive breast carcinoma with locally recurrent or radiological evidence of metastatic disease. Locally recurrent disease must not be amenable to resection with curative intent. the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: HER2+ status defined as IHC 3+ staining or in situ hybridization positive the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Patients with resistance to trastuzumab the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Prior taxane therapy the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Patients with an ECOG performance status of 0 - 2 the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Patients with measurable disease as per RECIST criteria the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Documentation of negative pregnancy test for patients of child bearing potential prior to enrollment within 7 days prior to randomization. Sexually active pre-menopausal women must use adequate contraceptive measures, excluding estrogen containing contraceptives, while on study; the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Patients must meet laboratory criteria defined in the study within 21 days prior to randomization the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |
b97d9465-db14-43af-9451-4b824e67abb8 | primary trial: Patients who have received hyperthermia to the target area within 10 weeks prior to first dosing of study agent. secondary trial: Prior mTOR inhibitors or vinca alkaloid agents for the treatment of cancer the primary trial and the secondary trial use different inclusion criteria for their cohorts, so patients may be eligible for one cohort, but not the other. | 0 |