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Oral bleeding in Ebola virus disease.
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Rectal bleeding in Ebola virus disease.
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Severe crusted scabies of the right axilla and chest wall.
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Fissure over the wrist with underlying less severe crusted scabies.
5
Physical examination of a Malawian patient with back pain and difficulties walking.
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AP radiograph demonstrating a paravertebral soft tissue mass in the lower dorsal region with collapse of the T11 vertebral body.
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Numerous painful ulcers on the penis, scrotum and inner thigh.
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Follow-up after 1 week of antibiotic therapy.
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Stool culture growing Vibrio cholerae which produces typical golden-yellow colonies on thiosulphate citrate bile salt sucrose (TCBS) agar.
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A Lao boy with a unilateral parotid mass showing signs of local inflammation.
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Multiple umbilicated papular skin lesions on the neck.
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Histology of the supraclavicular lymph node showing multiple round-shaped yeast-like structures (PAS stain,  400).
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The patient’s left eye showing corneal opacities.
14
Subcutaneous nodule over the costal arch.
15
Lesion at first consultation.
16
Follow-up image after 20 days of treatment.
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Follow-up image of the scar 3 months after the end of treatment.
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Chest radiograph showing nodular changes in the periphery of both lungs.
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Schistosoma mansoni egg.
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Papulovesicular lesion with extensive neck oedema 2 days after the onset of a small papule.
21
Chest radiograph on admission, showing bilateral perihilar infiltrates.
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CT scan of the chest showing bilateral ground-glass infil- trates, but no pulmonary emboli.
23
A 14-year-old boy from rural Tanzania with spastic paraparesis.
24
Lower legs of the patient at presentation with fungating lesions on his left foot that spread centripetally up to his knee.
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Characteristic brownish sclerotic cells in skin scrapings (100, oil immersion, wet film).
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The right foot and ankle with extensive tissue necrosis 3 weeks after a snake bite.
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After several debridements the wound looks clean.
28
Jaundice and subconjunctival haemorrhages.
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Sheathed microfilaria of Loa loa.
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(A) There is complete ptosis on the left.
31
Ziehl–Neelsen stain of CSF sample showing acid-fast bacilli (arrows).
32
The right eye showing lid scarring, trichiasis and extensive corneal opacification.
33
The left eye with a focal corneal scarring including a perfo- rated corneal ulcer with adherent iris (leucoma).
34
Scaling of the erythematous rash.
35
Wound on the patient’s left shoulder, after incision and drain- age of the abscess.
36
Admission chest radiograph of the patient, showing bilateral pleural effusions.
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Chest radiograph on admission showing a prominent hilar region.
38
Chest radiograph of a patient with miliary TB.
39
Initial ulcerated lesion on the left hand.
40
Multiple subcutaneous nodules along the lymphatic tract.
41
Abducens nerve palsy on the left in a patient with sub-acute headache.
42
Photomicrograph of Cryptococcus neoformans (India Ink stain).
43
Massive unilateral scrotal swelling.
44
Hyperpigmented skin rash on sun-exposed skin.
45
The skin changes involve both hands and feet.
46
-1 Cerebral MRI of the patient.
47
Examples of genuine (A) and falsified (B) artemether-lumefantrine discovered in Africa.
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Examples of genuine (A) and falsified (B) artemether-lumefantrine discovered in Africa.
49
White-centred haemorrhages and retinal whitening, both fea- tures of malaria retinopathy (Courtesy Dr Nicholas Beare).
50
Infant with cerebral malaria hospitalized at Queen Elizabeth Central Hospital, Blantyre, Malawi (Courtesy Mr James Peck).
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Large skin ulcer on the back of the right hand filled with necrotic tissue; second smaller ulcer on the medial side of the wrist.
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At the end of specific treatment, the ulcer on the back of the hand had healed almost completely.
53
Three track-like skin eruptions on both upper thighs causing intense itching.
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Left eye with marked axial proptosis, nasal upper lid covered with tetracycline eye ointment.
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Squamous cell carcinoma of the conjunctiva (SCCC).
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A child is receiving liposomal amphotericin B on a paediatric ward in South Sudan.
57
The patient’s “health passport”.
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Increasing and fluctuant lymphadenitis in the neck.
59
A patient with an acute-onset flaccid paraplegia.
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Fresh preparation showing trophozoites (A) and formol-ether concentration showing cysts (B) of Giardia species.
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Fresh preparation showing trophozoites (A) and formol-ether concentration showing cysts (B) of Giardia species.
62
A 4-year-old Lao boy with a necrotizing lesion on the right cheek.
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At age 9 after two surgeries correcting facial contractures and salivary incontinence.
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Ultrasound scan of the liver at diagnosis 3 years before current presentation reveals two cystic lesions.
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Computed tomography of the same patient.
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Pronator drift on the left side as a sign of left upper limb weak- ness.
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Thin smear showing massive infestation of red blood cells with cocco-bacillary structures (Wright stain).
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Multiple erythematous-violaceous papules of different sizes characteristic of the chronic phase (verruga peruana).
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Small necrotic skin lesion (about 0.7cm in diameter) with surrounding inflammation and lymphangiitis on the left upper thigh of the patient.
73
Chest radiograph showing bilateral confluent reticulonodular infiltrates predominantly in the central and upper zones of both lungs.
74
Large budding yeast (range: 8–40 μm) with multiple sur- rounding smaller buds around (arrows) seen on KOH preparation of the patient’s sputum.
75
Generalized, non-itchy macular rash in a pregnant Gambian woman.
76
Congenital syphilis in a 3-month-old infant: desquamating lesion of the palms.
77
Ultrasound of the liver showing pipestem fibrosis (CourtesyProf. Joachim Richter).
78
Helminth ova in a stool sample of a 25-year-old woman from Egypt with chronic diarrhoea.
79
Adult C. philippinensis in the patient’s stool sample during treatment with mebendazole.
80
Facial swelling and dark-purplish skin lesions on chest and nose of the patient.
81
Swollen right leg with prominent coalescing dark plaques.
82
Chest radiograph showing bilateral peribronchovascular infil- tration in the lower and mid lung zones.
83
Itchy serpiginous rash tracking up the right shoulder.
84
A picture taken after treatment of the mass tracking down the patient’s forehead.
85
The boy before four courses of chemotherapy.
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The boy after four courses of chemotherapy.
87
Histology of Burkitt’s lymphoma (H&E stain) showing monomorphic tumour cells of intermediate size, indistinct nuclei with coarse chromatin and vacuoles in the cytoplasm (100 high-power field).
88
Subcutaneous abscess on the left forearm.
89
Radiograph of the left elbow, showing osteolytic lesions of the radial epicondylus, osteomyelitis and articular effusion.
90
The patient’s left leg showing an ulcer surrounded by hyper- pigmented skin on the medial malleolus.
91
Patient’s blood film: irreversibly sickled cells (S), polychroma- sia (P), target cells (TC), nucleated red cells (NRC) – note similarity with lymphocyte (L).
92
T2-weighted MRI scan of the spinal cord.
93
Romanowski–Giemsa stain of the CSF sample revealing large numbers of eosinophils with red (eosinophilic) cytoplasm.
94
Small nodule on the fifth toe of right foot.
95
Microscopic examination of removed tissue containing parts of female flea (arrow) and typical eggs (size 600  280 μm).
96
Chest radiograph of the patient showing an enlarged globular cardiac silhouette with clear lung fields.
97
A contrast-enhanced CT scan showing multiple, round, clustered, hypodense lesions in left median section of liver (A, axial cross-section; B, lateral view).
98
A contrast-enhanced CT scan showing multiple, round, clustered, hypodense lesions in left median section of liver (A, axial cross-section; B, lateral view).
99
The face of the patient, showing bilateral swelling of the eyes with conjunctivitis and swollen lips with haemorrhagic crusts.
100
The right leg of another patient with SJS/TEN showing exten- sive epidermal sloughing and large areas of denuded dermis.
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