Toyokolabs/retinoblastoma · Datasets at Hugging Face

instruction stringlengths 30 82	output stringlengths 13 790
What is the type of genetic variation for RS1566233014 SNP?	The variation is a Duplication.
Which condition is asociated with RS587778833 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778833 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778833 SNP.
In which chromosome is RS587778833 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778833 SNP?	Associated methods are: research.
What is the clinical significance of RS587778833 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778833 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778833 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778833 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778833 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778865 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778865 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778865 SNP.
In which chromosome is RS587778865 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778865 SNP?	Associated methods are: research.
What is the clinical significance of RS587778865 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778865 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778865 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778865 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778865 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778866 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778866 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778866 SNP.
In which chromosome is RS587778866 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778866 SNP?	Associated methods are: research.
What is the clinical significance of RS587778866 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778866 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778866 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778866 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778866 SNP?	The resulting gene consequence is a missense variant.
Which condition is asociated with RS587778834 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778834 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778834 SNP.
In which chromosome is RS587778834 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778834 SNP?	Associated methods are: research, clinical testing.
What is the clinical significance of RS587778834 SNP, is it benign or pathogenic?	It is Uncertain significance.
How long is the variation length for RS587778834 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778834 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778834 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778834 SNP?	The resulting gene consequence is a missense variant.
Which condition is asociated with RS587778859 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778859 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778859 SNP.
In which chromosome is RS587778859 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778859 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778859 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778859 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778859 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778859 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778859 SNP?	The resulting gene consequence is a missense variant.
Which condition is asociated with RS587778835 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778835 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778835 SNP.
In which chromosome is RS587778835 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778835 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778835 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778835 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778835 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778835 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778835 SNP?	The resulting gene consequence is a missense variant.
Which condition is asociated with RS587778868 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778868 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778868 SNP.
In which chromosome is RS587778868 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778868 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778868 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778868 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778868 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778868 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778868 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778861 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778861 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778861 SNP.
In which chromosome is RS587778861 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778861 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778861 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778861 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778861 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778861 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778861 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778826 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778826 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778826 SNP.
In which chromosome is RS587778826 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778826 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778826 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778826 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778826 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778826 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778826 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with 132325?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/Rs132325. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/132325.
In which chromosome is 132325 located?	It is located in the chromosome 13.
Which methods support the evidence found for the 132325?	Associated methods are: research.
What is the clinical significance of 132325, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for 132325?	The variation length is None base pairs.
What is the origin for 132325?	The origin is somatic.
What is the type of genetic variation for 132325?	The variation is a Variation.
Which condition is asociated with RS587778843 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778843 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778843 SNP.
In which chromosome is RS587778843 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778843 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778843 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778843 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778843 SNP?	The origin is somatic.
What is the type of genetic variation for RS587778843 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778843 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778855 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778855 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778855 SNP.
In which chromosome is RS587778855 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778855 SNP?	Associated methods are: research.
What is the clinical significance of RS587778855 SNP, is it benign or pathogenic?	It is Pathogenic.
How long is the variation length for RS587778855 SNP?	The variation length is 1 base pairs.
What is the origin for RS587778855 SNP?	The origin is germline.
What is the type of genetic variation for RS587778855 SNP?	The variation is a single nucleotide variant.
What is the genetic molecular consequence for RS587778855 SNP?	The resulting gene consequence is a nonsense.
Which condition is asociated with RS587778856 SNP?	Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778856 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778856 SNP.
In which chromosome is RS587778856 SNP located?	It is located in the chromosome 13.
Which methods support the evidence found for the RS587778856 SNP?	Associated methods are: clinical testing.
What is the clinical significance of RS587778856 SNP, is it benign or pathogenic?	It is Uncertain significance.

What is the type of genetic variation for RS1566233014 SNP?

The variation is a Duplication.

Which condition is asociated with RS587778833 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778833 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778833 SNP.

In which chromosome is RS587778833 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778833 SNP?

Associated methods are: research.

What is the clinical significance of RS587778833 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778833 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778833 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778833 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778833 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778865 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778865 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778865 SNP.

In which chromosome is RS587778865 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778865 SNP?

Associated methods are: research.

What is the clinical significance of RS587778865 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778865 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778865 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778865 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778865 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778866 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778866 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778866 SNP.

In which chromosome is RS587778866 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778866 SNP?

Associated methods are: research.

What is the clinical significance of RS587778866 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778866 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778866 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778866 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778866 SNP?

The resulting gene consequence is a missense variant.

Which condition is asociated with RS587778834 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778834 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778834 SNP.

In which chromosome is RS587778834 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778834 SNP?

Associated methods are: research, clinical testing.

What is the clinical significance of RS587778834 SNP, is it benign or pathogenic?

It is Uncertain significance.

How long is the variation length for RS587778834 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778834 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778834 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778834 SNP?

The resulting gene consequence is a missense variant.

Which condition is asociated with RS587778859 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778859 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778859 SNP.

In which chromosome is RS587778859 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778859 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778859 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778859 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778859 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778859 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778859 SNP?

The resulting gene consequence is a missense variant.

Which condition is asociated with RS587778835 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778835 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778835 SNP.

In which chromosome is RS587778835 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778835 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778835 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778835 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778835 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778835 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778835 SNP?

The resulting gene consequence is a missense variant.

Which condition is asociated with RS587778868 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778868 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778868 SNP.

In which chromosome is RS587778868 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778868 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778868 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778868 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778868 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778868 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778868 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778861 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778861 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778861 SNP.

In which chromosome is RS587778861 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778861 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778861 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778861 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778861 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778861 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778861 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778826 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778826 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778826 SNP.

In which chromosome is RS587778826 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778826 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778826 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778826 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778826 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778826 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778826 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with 132325?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/Rs132325. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/132325.

In which chromosome is 132325 located?

It is located in the chromosome 13.

Which methods support the evidence found for the 132325?

Associated methods are: research.

What is the clinical significance of 132325, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for 132325?

The variation length is None base pairs.

What is the origin for 132325?

The origin is somatic.

What is the type of genetic variation for 132325?

The variation is a Variation.

Which condition is asociated with RS587778843 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778843 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778843 SNP.

In which chromosome is RS587778843 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778843 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778843 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778843 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778843 SNP?

The origin is somatic.

What is the type of genetic variation for RS587778843 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778843 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778855 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778855 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778855 SNP.

In which chromosome is RS587778855 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778855 SNP?

Associated methods are: research.

What is the clinical significance of RS587778855 SNP, is it benign or pathogenic?

It is Pathogenic.

How long is the variation length for RS587778855 SNP?

The variation length is 1 base pairs.

What is the origin for RS587778855 SNP?

The origin is germline.

What is the type of genetic variation for RS587778855 SNP?

The variation is a single nucleotide variant.

What is the genetic molecular consequence for RS587778855 SNP?

The resulting gene consequence is a nonsense.

Which condition is asociated with RS587778856 SNP?

Retinoblastoma is a malignant tumor of the developing retina that occurs in children, usually before age five years. Retinoblastoma develops from cells that have cancer-predisposing variants in both copies of RB1. Retinoblastoma may be unifocal or multifocal. About 60% of affected individuals have unilateral retinoblastoma with a mean age of diagnosis of 24 months; about 40% have bilateral retinoblastoma with a mean age of diagnosis of 15 months. Heritable retinoblastoma is an autosomal dominant susceptibility for retinoblastoma. Individuals with heritable retinoblastoma are also at increased risk of developing non-ocular tumors. The associated SNPedia page is https://www.snpedia.com/index.php/RsRS587778856 SNP. The NCBI page is https://www.ncbi.nlm.nih.gov/snp/RS587778856 SNP.

In which chromosome is RS587778856 SNP located?

It is located in the chromosome 13.

Which methods support the evidence found for the RS587778856 SNP?

Associated methods are: clinical testing.

What is the clinical significance of RS587778856 SNP, is it benign or pathogenic?

It is Uncertain significance.