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Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: One week later, the patient was again extubated and 3 days later was transferred to a peripheral ward.
Output:
|
[
"non-adverse drug event"
] |
task1495-94f9937ec6b14638a5e3a89304f34808
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Here, we describe a case of Epstein-Barr virus-associated polymorphic PTLD that developed shortly after treatment for cytomegalovirus reactivation in a lung transplant recipient who was preoperatively seropositive for both cytomegalovirus and Epstein-Barr virus.
Output:
|
[
"non-adverse drug event"
] |
task1495-57cb98d4a0bf41c7b2d955c77c316372
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In December 1998, he applied to our clinic for a follow-up examination.
Output:
|
[
"non-adverse drug event"
] |
task1495-d012f936bfe24029bfdbe82343b04056
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Classification included dry (7%), mild (48%), moderate (39%), and severe (6%).
Output:
|
[
"non-adverse drug event"
] |
task1495-b7e27b7caa9e44ab97571c31c1af8d01
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Mycophenolate mofetil-induced neutropenia in liver transplantation.
Output:
|
[
"adverse drug event"
] |
task1495-86257a882ed041d49137fbf68dc478c2
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Intravenous valproate has been suggested for the treatment of status epilepticus in part because of its relatively good cardiovascular safety profile.
Output:
|
[
"non-adverse drug event"
] |
task1495-0419f67438564d58b73a03eaa9b8b5db
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We have successfully overcome severe neutropenia in an RA patient treated with gold salts, using granulocyte colony-stimulating factor (G-CSF), reducing the duration of neutropenia and risk of infection.
Output:
|
[
"adverse drug event"
] |
task1495-472bf2d517a14e3bac18b54a70235e7b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Gold nephropathy.
Output:
|
[
"adverse drug event"
] |
task1495-21f631690db04dc7bf31d59a758b6d84
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: He was successfully transplanted.
Output:
|
[
"non-adverse drug event"
] |
task1495-22d3b5265aa84884bcd272acdb7f8040
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report.
Output:
|
[
"adverse drug event"
] |
task1495-2b5acdff302846d2b8c7b6aca0f08f8d
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Pure red cell aplasia (PRCA) is a rare complication after ABO-incompatible allogeneic stem cell transplantation, but its mechanism is still unknown.
Output:
|
[
"non-adverse drug event"
] |
task1495-ab6fd98e659c4eefb3361c546e537c60
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Osteonecrosis is a feared complication of corticosteroid use.
Output:
|
[
"non-adverse drug event"
] |
task1495-5db43758cac5432195bd70b6eeded9d8
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We report the case histories of identical twin brothers who developed concordant acute lymphoblastic leukemia at the age of 4 years and who later developed leukoencephalopathy and hydrocephalus related to central nervous system prophylaxis by, in the first case intrathecally administered methotrexate and, in the second by intrathecally administered methotrexate and cranial irradiation.
Output:
|
[
"adverse drug event"
] |
task1495-0d3429b642624357b6a808a017730137
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Unusual side-effects due to clobazam: a case report with genetic study of CYP2C19.
Output:
|
[
"non-adverse drug event"
] |
task1495-2c07935d3d014d4295bcdd4604ed5355
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: These data further suggest that degradation by the ubiquitin-proteosome-mediated system plays a role in the elimination of the DPD protein.
Output:
|
[
"non-adverse drug event"
] |
task1495-54c0fbd997aa4b38a9e68de7c285fca7
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: CONCLUSION: We conclude that stanozolol is a safe and effective treatment of the cutaneous manifestations of cryofibrinogenemia.
Output:
|
[
"non-adverse drug event"
] |
task1495-feef5b89c86040b1892bfb3849c5bc1b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The recognition of the characteristic features of the syndrome is vital since early aggressive therapy is indicated.
Output:
|
[
"non-adverse drug event"
] |
task1495-ec06c6856688490c929f2d074e86a2c6
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Initially, she responded well to corticosteroids, but relapsed when medication was discontinued.
Output:
|
[
"non-adverse drug event"
] |
task1495-c520f224f7c94a4ab04cd93b5cf3471f
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: RESULTS: A complete response (CR) was obtained for all three patients, resulting in a response rate of 100%.
Output:
|
[
"non-adverse drug event"
] |
task1495-41f4bbb5aa7d4855b8e5a1f345d9a5e2
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: This is a report of a renal transplant patient with Pneumocystis pneumonia who developed chemical cellulitis and ulceration following the extravasation of intravenous pentamidine into the soft tissues of the left hand and forearm.
Output:
|
[
"adverse drug event"
] |
task1495-9f42b8a7f3844a8ea0c5eb16606065f7
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The reversible posterior leukoencephalopathy syndrome (RPLES) is a condition characterised by reversible neurological and radiological findings that has been associated with use of immunosuppressive, chemotherapeutic and more recently novel targeted therapies.
Output:
|
[
"non-adverse drug event"
] |
task1495-88a2ca25414949a7a37f4399f91ab75f
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Although hypophosphatemia induced by aluminum-containing antacids is rare, treatment of peptic ulcer disease with a combination of two aluminum-containing agents may increase the risk of clinically significant hypophosphatemia.
Output:
|
[
"non-adverse drug event"
] |
task1495-286bcaf01a7e402ba1d33e238992f2da
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A patient developed restless legs symptoms paralleling the course of interferon-alpha (IFN alpha) therapy for chronic hepatitis C.
Output:
|
[
"adverse drug event"
] |
task1495-c89d8e65b3e84dd9949ce782da5c7986
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In this case, it was suspected that a combination of cigarette smoking, pulmonary fibrosis, and low-dose methotrexate therapy might have promoted the development of lung cancer.
Output:
|
[
"adverse drug event"
] |
task1495-af6aac4943dd4faaaed5766f5cc86644
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: During her life the patient frequently presented catamenial MA attacks with an increasing frequency during pregnancy in particular in the second and third trimesters, and then during breast-feeding.
Output:
|
[
"non-adverse drug event"
] |
task1495-1327f564f35a49c9bf1e6b5149690ec9
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: No re-occurrence of pancreatitis was observed in a 16 month follow-up.
Output:
|
[
"non-adverse drug event"
] |
task1495-8cc672c9ae0348ada6be15b7240e6c0a
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The use of rituximab has been uncommonly associated with delayed pulmonary toxicity.
Output:
|
[
"adverse drug event"
] |
task1495-db1e4aae4ca04bf0b0d14699e2fe1f66
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We describe the clinical and liver biopsy morphologic features for 4 patients with minocycline-induced autoimmune hepatitis (group 1).
Output:
|
[
"adverse drug event"
] |
task1495-88b9607cc1354e84a059c4da67fdbc50
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The decedent was also prescribed tramadol, gabapentin, cetirizine, modafinil, carisoprodol, and Xyrem.
Output:
|
[
"non-adverse drug event"
] |
task1495-7d617c73b11e440c8f7a6bc08b046cea
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Progressive hypoxemia mandated endotracheal intubation 1 week after rituximab administration and led to death 4 weeks after admission.
Output:
|
[
"adverse drug event"
] |
task1495-8bc74a674d04426e8585107034a16261
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: There was no evidence of recurrent myeloma after the initial remission on cyclophosphamide therapy.
Output:
|
[
"non-adverse drug event"
] |
task1495-ec9d6016625a4a39b9bef69d1e15c916
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Retrospectively, bucillamine was believed to be the cause of the giant hypertrophy because of its structural similarity to D-penicillamine, which was the subject of an abundance of reports of mammary hyperplasia.
Output:
|
[
"adverse drug event"
] |
task1495-7d431f84817246dd854cde6f8e823243
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Paralytic ileus in patients undergoing bortezomib treatment has been reported, although a definite attribution to bortezomib administration has not been established.
Output:
|
[
"adverse drug event"
] |
task1495-a07e33310e034c559199fa68b5e0f645
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Drug-induced fever should be considered in patients who have unexplained high temperatures during diltiazem therapy.
Output:
|
[
"adverse drug event"
] |
task1495-49a784036c57442db36660efd0a8eaa1
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Reversal of CNS-prophylaxis-related leukoencephalopathy after CSF shunting: case histories of identical twins.
Output:
|
[
"non-adverse drug event"
] |
task1495-7e0961400e684819afc866264cc16d6b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Aminophylline hypersensitivity apparently due to ethylenediamine.
Output:
|
[
"adverse drug event"
] |
task1495-d9b877f821ad47b5ad842517093be3ea
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: PURPOSE: To describe bilateral optic neuritis that occurred as an adverse effect of recombinant and natural interferon alpha administration.
Output:
|
[
"adverse drug event"
] |
task1495-2e0e9c44a5e34b6684e32f0810483e25
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A 17-year-old boy with refractory psoriatic arthritis and alpha-1 antitrypsin deficiency who developed a syringotropic hypersensitivity reaction after 9 months of therapy with infliximab and leflunomide is described.
Output:
|
[
"adverse drug event"
] |
task1495-b4148dbeba9e4ac8a85160ba124f0a6b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Considerable improvement of myasthenic symptoms was seen in all patients within 3-6 months after the initiation of this therapy.
Output:
|
[
"non-adverse drug event"
] |
task1495-c7dc791c62f748348ad6e0ce02cc5c52
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Paradoxical precipitation of tonic seizures by lorazepam in a child with atypical absence seizures.
Output:
|
[
"adverse drug event"
] |
task1495-51b1bd85bc1140b089c3b771a7017e35
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: So this potential drug-drug interaction could be investigated, the patient stopped taking both drugs for 1 week.
Output:
|
[
"non-adverse drug event"
] |
task1495-20294dc75c93428f9fbb24b3a4f9b0a3
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In all cases SMS 201-995 treatment has been well tolerated and has few side-effects.
Output:
|
[
"non-adverse drug event"
] |
task1495-63946623ef78435c8da26acfa42819d3
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In each of the three reported patients, alteration of eyelid appearance with deepening of the lid sulcus was evident as the result of topical bimatoprost therapy.
Output:
|
[
"adverse drug event"
] |
task1495-0097ed2f5f9b4f7eab3441b34ab9ee5c
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Mean duration of therapy was 5.5 yrs.
Output:
|
[
"non-adverse drug event"
] |
task1495-c21d32e680cd40b3a8cea778ecf4b607
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Myoclonus associated with continuous dobutamine infusion in a patient with end-stage renal disease.
Output:
|
[
"adverse drug event"
] |
task1495-d3e6756e21244c88bf1d4c295a6d60ce
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Our report points out differences between acute, postacute, and longterm rehabilitation, describes the mobilization of patients in acute rheumatology units, and defines specific problems encountered in acute hospital-based rehabilitation of rheumatological patients.
Output:
|
[
"non-adverse drug event"
] |
task1495-c062015724c74909a291eb9a6a133a4c
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Carbamazepine-induced systemic lupus erythematosus-like disease.
Output:
|
[
"adverse drug event"
] |
task1495-09f55b5fe33a436c974257a80bd81d4e
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The oligohidrosis caused by zonisamide was reversible in that the patient regained the ability to sweat within 2 weeks of the cessation of drug administration.
Output:
|
[
"adverse drug event"
] |
task1495-641849d6c5ee409ab6c0e94d48f40b5a
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We have recently encountered a patient with acquired haemophilia who developed a thrombotic left middle cerebral artery distribution stroke while being treated with pFVIII.
Output:
|
[
"adverse drug event"
] |
task1495-da37a0b6e516435e9380cc4b4777f4b2
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Due to the severity of the rash, temozolomide was permanently discontinued.
Output:
|
[
"adverse drug event"
] |
task1495-320c0c3574134c7987e3b93d28034130
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: No recurrence was seen in the 12 to 19 month follow-up.
Output:
|
[
"non-adverse drug event"
] |
task1495-65223124fe82400dad85b98982bbb912
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Anaphylactoid reactions with intraperitoneal cisplatin.
Output:
|
[
"adverse drug event"
] |
task1495-b5389bd5a23c4e9f89330970dff0cccd
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Systemic cytomegalovirus infection complicating ulcerative colitis: a case report and review of the literature.
Output:
|
[
"non-adverse drug event"
] |
task1495-8a991e14e3884dde80006f186374ba5b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Complications in the use of prochlorperazine.
Output:
|
[
"non-adverse drug event"
] |
task1495-e0d2a19744264d4db7ce3734e20c286f
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Reversible sclerotic changes of lumbar spine and femur due to long-term oral isotretinoin therapy.
Output:
|
[
"adverse drug event"
] |
task1495-c02c9ce59ce145eda7e7f02127bd41e0
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: No cases of renal acidosis, and only one case of nephrogenic diabetes insipidus, has been previously reported as a complication of foscarnet treatment.
Output:
|
[
"adverse drug event"
] |
task1495-5c6c6a8375f74e94836fe1d1bf651310
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects.
Output:
|
[
"adverse drug event"
] |
task1495-f0c3621303e44879a95eacb223bb8469
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The most commonly recognized toxic effect of ethambutol is optic neuropathy, which generally is considered uncommon and reversible in medical literature.
Output:
|
[
"adverse drug event"
] |
task1495-aa5c73f87cb44590addff6ef3b4082af
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Cephalexin rash in infectious mononucleosis.
Output:
|
[
"adverse drug event"
] |
task1495-0aa2f5d2982446118107884a6993b37f
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We conclude that while thrombocytopenia and schistocytosis can be seen in quinine-associated TTP/HUS, the pathophysiology seems to be distinct from that seen in most cases of idiopathic TTP (i.e., severely decreased ADAMTS13 with an inhibitor).
Output:
|
[
"adverse drug event"
] |
task1495-1658b02c49f24369a2be0d5b5532e323
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: CONCLUSION: The results suggest that olanzapine may be useful in treating patients with clozapine-induced granulocytopenia without the risk of recurrence of hematologic side effects.
Output:
|
[
"adverse drug event"
] |
task1495-7ae1369815d247f4a88ca498470a937a
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Little inflammatory change was noted in either the epithelial or stromal layers of the failed graft.
Output:
|
[
"non-adverse drug event"
] |
task1495-4c9a58debed04f0cb11259fc425e67b2
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: DISCUSSION: According to the literature, reversible nonthrombocytopenic palpable purpura has not been previously reported with metoclopramide.
Output:
|
[
"non-adverse drug event"
] |
task1495-c56af063146548d2aef603a08138badf
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Acute aluminum toxicity after continuous intravesical alum irrigation for hemorrhagic cystitis.
Output:
|
[
"adverse drug event"
] |
task1495-d8ac3b90b0c44ac998c3f8df1701dc23
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation.
Output:
|
[
"adverse drug event"
] |
task1495-fdb04cd5de2942dd931e3b8f3095ea63
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Asthmatic medications can place the patient at risk of dental erosion by reducing salivary protection against extrinsic or intrinsic acids.
Output:
|
[
"non-adverse drug event"
] |
task1495-fedddb88442e4904aeec35ca7615b12b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: This case is the first report in which RLS augmentation is shown to be characterized by motor hyperkinesias paralleling levodopa plasma pharmacokinetic profile.
Output:
|
[
"non-adverse drug event"
] |
task1495-5ce0432173ba4333a662bba69bd5e688
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: It is severe enough to require discontinuation of therapy in 1-10 percent of patients.
Output:
|
[
"non-adverse drug event"
] |
task1495-114fdb1d5a174a16af3fab878d0871cb
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Aripiprazole-induced hiccups: a case report.
Output:
|
[
"adverse drug event"
] |
task1495-9f481b7ac759453f9fc297a754f01aeb
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Tetany in a child with AIDS receiving intravenous tobramycin.
Output:
|
[
"adverse drug event"
] |
task1495-25e2be5810454fc8bff08f1a05f859dd
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Due to the increasing use of TMP-SMX in children, clinicians should be aware of this potentially life-threatening, immunemediated hypersensitivity reaction.
Output:
|
[
"adverse drug event"
] |
task1495-94e81117896440059172050421bc361d
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: OBJECTIVE: We identified a group of patients with rheumatoid arthritis (RA) who were sensitive to both the beneficial and the side effects of intramuscular (im) gold treatment and whose disease was well controlled with doses of gold between 2 mg every 6 weeks and 5 mg weekly.
Output:
|
[
"non-adverse drug event"
] |
task1495-42843cf6d6ea4c2ca367cce232310e35
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We suggest the use of trihexyphenidyl in combination with isoprinosine in patients with subacute sclerosing panencephalitis with myoclonic seizures refractory to valproic acid.
Output:
|
[
"non-adverse drug event"
] |
task1495-fb9a45d389764cd785f263c0ac331bf0
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In two patients, adenosine precipitated acceleration of ventricular response, in one case necessitating emergent cardioversion.
Output:
|
[
"non-adverse drug event"
] |
task1495-2c74923eeb3c44bb8c675f61f3d09e88
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Interstitial fibrosis of the lung is a potential complication of methotrexate therapy for psoriasis.
Output:
|
[
"adverse drug event"
] |
task1495-6c4e4b7ae2a64f07a0c50c2487533164
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: She was transfused with four (4) units of packed cells and Zidovudine was replaced with Stavudine.
Output:
|
[
"non-adverse drug event"
] |
task1495-98000edae4334136afad6fcc65b4db80
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The aim of this phase I study was to determine the toxicity profile and the optimal dosage of KW-2149.
Output:
|
[
"non-adverse drug event"
] |
task1495-87e2c1238ef54255b5a9d4b1c228484b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: We report on a patient who underwent renal transplantation using Campath-1H induction and tacrolimus maintenance therapy who developed HUS, which was managed by plasma exchange and switch to Rapamycin.
Output:
|
[
"non-adverse drug event"
] |
task1495-3ff5d157b5d8444fa2576d244af8dcc9
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Six patients with no previous signs or symptoms suggestive of coronary artery disease developed acute coronary ischemia/infarction shortly after cis-diamine-dichloroplatinum II (cisplatin) -based chemotherapy.
Output:
|
[
"adverse drug event"
] |
task1495-a659990450714bc88b0db5d8ba8c0458
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Seven patients only smoked at night-time (median dose eight puffs, range two to eight puffs), and eight patients used cannabis mainly during the day (median dose three puffs, range two to eight puffs); the median frequency of use was four times per day (range one to 16 times per day).
Output:
|
[
"non-adverse drug event"
] |
task1495-fbc54f7d7ce14584a98527f0cd6b2283
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Pyomyositis was completely resolved following the surgical drainage and the antistaphylococcal antibiotic treatment.
Output:
|
[
"non-adverse drug event"
] |
task1495-44e534f311cc4410b0631773754716b8
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A 72-year-old woman with a history of thyrotoxicosis presented with sore throat and fever two weeks after starting carbimazole.
Output:
|
[
"adverse drug event"
] |
task1495-91ca83f0cba44c42ada454a3410a8cf2
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A second possibility is an interaction between clarithromycin and isradipine, potentially increasing the hepatic toxicity of isradipine.
Output:
|
[
"adverse drug event"
] |
task1495-2fec21b3d253420fa106f9a8d12ba1ae
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: In this report, we suppose the possibility to develop a foetal malformations after a long-term wash out from isotretinoin therapy.
Output:
|
[
"non-adverse drug event"
] |
task1495-97eb7f77c16f46e8816109f95f326ff4
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Toxic streptococcal syndrome is characterized by fever, shock, multiorgan system failure and a desquamating scarlatiniform rash.
Output:
|
[
"non-adverse drug event"
] |
task1495-a6075da7413d49da982b39241a686234
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented.
Output:
|
[
"adverse drug event"
] |
task1495-8f138794bd4c4b91b6236545b8531405
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: As with any new therapy, we suggest waiting for the results of a randomized, controlled trial before recommending this treatment.
Output:
|
[
"non-adverse drug event"
] |
task1495-9fe24085eb034418bd778a54bf7dfd06
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Proposed mechanisms for leukemogenesis are presented.
Output:
|
[
"non-adverse drug event"
] |
task1495-c245f4530d5d4927bf434fd67448fd98
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A case of acute cardiomyopathy and pericarditis associated with methylphenidate.
Output:
|
[
"adverse drug event"
] |
task1495-b8f4348c76144ef59547350bed7ddb1e
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The mean duration of clozapine treatment was 12.10+/-6.26 years.
Output:
|
[
"non-adverse drug event"
] |
task1495-3f069db970c84a2789429a729cfcc69a
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Paroxysmal supraventricular tachycardia during treatment with cisplatin and etoposide combination.
Output:
|
[
"adverse drug event"
] |
task1495-e2b91e6e15bc404bb84ed39d840d255c
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A pattern of possible risk factors emerges from these reports.
Output:
|
[
"non-adverse drug event"
] |
task1495-a1abd481d7e54d40ad3c54fc95d4858b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Pathology evaluation of a specimen revealed a high-grade osteoblastic osteosarcoma.
Output:
|
[
"non-adverse drug event"
] |
task1495-2cfa80bd75f945dea1b97d992be80a0b
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Bacteremia due to Enterococcus avium.
Output:
|
[
"non-adverse drug event"
] |
task1495-55bec3f5932d41fbb9f9f5c36d067f68
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Two cases of childhood-onset schizophrenia associated with clozapine-induced akathisia responsive to beta-blocker treatment are described.
Output:
|
[
"adverse drug event"
] |
task1495-80ad9cddcd764a83ac0738f06fa97dbe
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Both the psoriasis and the HCL cleared.
Output:
|
[
"non-adverse drug event"
] |
task1495-31b4e959bb53448aa7632d38382c0725
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The patient was not obese.
Output:
|
[
"non-adverse drug event"
] |
task1495-c5d44387365e4610b956c9d7ba5b736f
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment.
Output:
|
[
"adverse drug event"
] |
task1495-f314f824ec9541a9b751038247f16d2d
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: A 58-year-old woman with rheumatoid arthritis (RA) developed fever, skin eruptions, leukocytopenia, and thrombocytopenia, 3 weeks after treatment with sulfasalazine.
Output:
|
[
"adverse drug event"
] |
task1495-ef96c3ca568241208a2b8b6772b9737c
|
Definition: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
Positive Example 1 -
Input: A case is reported of a child with fatal pulmonary fibrosis following BCNU therapy.
Output: adverse drug event
Positive Example 2 -
Input: She responded well to Sodium valproate.
Output: non-adverse drug event
Negative Example 1 -
Input: The patient suffered from breathing trouble after taking azithromycin.
Output: serious
Negative Example 2 -
Input: The patient is feeling better at the hospital.
Output: wellness
Now complete the following example -
Input: The patient did well after the operation and returned to normal activity.
Output:
|
[
"non-adverse drug event"
] |
task1495-86667e915ada44ffbf6b3b2a3cbf4b3c
|
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