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# METL
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<!-- Provide a quick summary of what the model is/does. -->
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Mutational Effect Transfer Learning (METL) is a framework for pretraining and finetuning biophysics-informed protein language models.
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### Model Description
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METL is discussed in the (paper)[https://www.biorxiv.org/content/10.1101/2024.03.15.585128v1] in further detail.
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### Model Sources [optional]
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- **Repository:** [https://github.com/gitter-lab/metl
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- **Paper:** [https://www.biorxiv.org/content/10.1101/2024.03.15.585128v1
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- **Demo:** [https://huggingface.co/spaces/gitter-lab/METL_demo
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## How to Get Started with the Model
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```
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##
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## Citation [optional]
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Biophysics-based protein language models for protein engineering
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Sam Gelman, Bryce Johnson, Chase Freschlin, Sameer D’Costa, Anthony Gitter, Philip A. Romero
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## Model Card Contact
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# METL
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Mutational Effect Transfer Learning (METL) is a framework for pretraining and finetuning biophysics-informed protein language models.
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### Model Description
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METL is discussed in the (paper)[https://www.biorxiv.org/content/10.1101/2024.03.15.585128v1] in further detail. The github contains more documentation and includes scripts for training and predicting with METL. A google colab notebook for finetuning and predicting on publically available METL models is made available as well [here](https://github.com/gitter-lab/metl/tree/main/notebooks).
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### Model Sources [optional]
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<!-- Provide the basic links for the model. -->
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- **Repository:** [METL Repo](https://github.com/gitter-lab/metl)
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- **Paper:** [METL bio archrive](https://www.biorxiv.org/content/10.1101/2024.03.15.585128v1)
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- **Demo:** [Huggingface demo space for METL](https://huggingface.co/spaces/gitter-lab/METL_demo)
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## How to Get Started with the Model
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```
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## Citation
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Biophysics-based protein language models for protein engineering
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Sam Gelman, Bryce Johnson, Chase Freschlin, Sameer D’Costa, Anthony Gitter, Philip A. Romero
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## Model Card Contact
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For questions and comments about METL, the best way to reach out is through opening a github issue in the [METL repository](https://github.com/gitter-lab/metl/issues) issues page.
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