text: Prematurity, measured in gestation weeks in this study, has also been regarded as a risk factor for the development of CMPA, due to immaturity of the gastrointestinal barrier, and even more so in those children that presented with hypoxia and intestinal ischemia, because it favors high molecular weight-antigen absorption, resulting in a greater probability for developing allergy.(10,13,14) In our study, even though we found no differences between the two groups, other studies have established prematurity as a probable factor associated with the development of allergies.