passages.id: IEPA.d46.s115
passages.text: Amyloid beta protein (25-35) stimulation of phospholipase C in LA-N-2 cells
passages.id: IEPA.d46.s116
passages.text: This phospholipase C stimulation by amyloid beta protein appeared to be pertussis toxin sensitive
passages.id: IEPA.d46.s117
passages.text: It is possible that this phospholipase C stimulation by amyloid beta protein is a receptor-mediated process
passages.id: IEPA.d46.s118
passages.text: Amyloid beta protein stimulation of phospholipase C was absent from LA-N-2 cells previously treated with norepinephrine, trans-1-amino-1,3-cyclopentanedicarboxylic acid (t-ACPD), bombesin, or amyloid beta peptide
passages.id: IEPA.d46.s119
passages.text: It is suggested that this observed amyloid beta protein stimulation of phospholipase C may be responsible for the elevated quantity of inositol seen in the brains of Alzheimer's disease patients