IEPA.d41.s100
Regulation of insulin secretion via ATP-sensitive K+ channel independent mechanisms: role of phospholipase C
IEPA.d41.s101
The further addition of carbachol, an agonist that activates an isozyme of phospholipase C distinct from that activated by glucose, together with K+, 20 mM glucose, plus diazoxide resulted in a sustained amplification of insulin secretion from mouse but not rat islets
IEPA.d41.s102
The inability to activate a nutrient- and calcium-regulated phospholipase C isozyme in mouse islets to the same extent as in rat islets appears to account, at least in part, for these different insulin secretory responses under these unique conditions