IEPA.d140.s335
Arginine vasopressin (AVP) and lysophosphatidic acid (LPA) have been shown to stimulate protein kinase C (PKC) and mitogen-activated protein (MAP) kinases and the proliferation of vascular smooth muscle cells
IEPA.d140.s336
However, AVP-induced activation of RSK2, a downstream substrate of ERK1 and ERK2, was PKC-dependent and PI 3-kinase-independent
IEPA.d140.s337
PKC was necessary in AVP- but not in LPA-induced activation of p70 S6K