IEPA.d76.s182
Melatonin inhibits oxytocin response to insulin-induced hypoglycemia, but not to angiotensin II in normal men
IEPA.d76.s183
In order to establish whether melatonin alters basal and/or stimulated oxytocin secretion, 18 normal men were treated (p.o.) with 6 or 12 mg melatonin or placebo in basal conditions (N-6 subjects) or concomitantly to the administration of insulin (O.15 IU/kg body weight in an i.v. bolus) (N-6 subjects) or angiotensin II (increasing doses of 4, 8 and 16 ng/kg/min, at intervals of 20 min)
IEPA.d76.s184
In contrast, the oxytocin response to insulin-induced hypoglycemia was significantly reduced by melatonin treatment