sentences.id: IEPA.d185.s442
sentences.origID: 149
sentences.text: The ARC NPY neurones are stimulated by starvation, probably mediated by falls in circulating leptin and insulin (which both inhibit these neurones), and contribute to the increased hunger in this and other conditions of energy deficit
sentences.id: IEPA.d185.s442.e0
sentences.origID: 331
sentences.text: NPY
sentences.id: IEPA.d185.s442.e1
sentences.origID: 332
sentences.text: leptin
sentences.id: IEPA.d185.s443
sentences.origID: 150
sentences.text: ARC NPY neurones also mediate hyperphagia and obesity in the ob/ob and db/db mice and fa/fa rat, in which leptin inhibition is lost through mutations affecting leptin or its receptor
sentences.id: IEPA.d185.s443.e0
sentences.origID: 333
sentences.text: NPY
sentences.id: IEPA.d185.s443.e1
sentences.origID: 334
sentences.text: leptin
sentences.id: IEPA.d185.s443.e2
sentences.origID: 335
sentences.text: leptin