sentences.id: IEPA.d165.s397
sentences.origID: 172
sentences.text: Interactions between leptin and NPY affecting lipid mobilization in adipose tissue
sentences.id: IEPA.d165.s397.e0
sentences.origID: 375
sentences.text: leptin
sentences.id: IEPA.d165.s397.e1
sentences.origID: 376
sentences.text: NPY
sentences.id: IEPA.d165.s397.i0
sentences.e1: IEPA.d165.s397.e0
sentences.e2: IEPA.d165.s397.e1
sentences.type: PPI
sentences.id: IEPA.d165.s398
sentences.origID: 173
sentences.text: The aim of the current investigations was focused on the study of the involvement of leptin and neuropeptide Y in lipid mobilization
sentences.id: IEPA.d165.s398.e0
sentences.origID: 377
sentences.text: leptin
sentences.id: IEPA.d165.s398.e1
sentences.origID: 378
sentences.text: neuropeptide Y
sentences.id: IEPA.d165.s399
sentences.origID: 174
sentences.text: The lipolytic rate was assessed through glycerol release after incubation with leptin and NPY at concentrations ranging from 10(-6) to 10(-12) M in isolated adipocytes obtained from female rats
sentences.id: IEPA.d165.s399.e0
sentences.origID: 379
sentences.text: leptin
sentences.id: IEPA.d165.s399.e1
sentences.origID: 380
sentences.text: NPY
sentences.id: IEPA.d165.s400
sentences.origID: 175
sentences.text: At equimolar concentrations of leptin and NPY (10(-12) to 10(-6) M) the observed lipolytic activity is comparable to the basal lipolytic activity, except at a concentration of 10(-9) M where upon a significant increase in lipolysis is observed
sentences.id: IEPA.d165.s400.e0
sentences.origID: 381
sentences.text: leptin
sentences.id: IEPA.d165.s400.e1
sentences.origID: 382
sentences.text: NPY
sentences.id: IEPA.d165.s401
sentences.origID: 176
sentences.text: Summing up, new evidence suggests that NPY and leptin may interact in a homeostatic loop to regulate body-fat mass and energy balance not only at the central nervous system level, but also directly at the adipocyte level
sentences.id: IEPA.d165.s401.e0
sentences.origID: 383
sentences.text: NPY
sentences.id: IEPA.d165.s401.e1
sentences.origID: 384
sentences.text: leptin
sentences.id: IEPA.d165.s401.i0
sentences.e1: IEPA.d165.s401.e0
sentences.e2: IEPA.d165.s401.e1
sentences.type: PPI