sentences.id: IEPA.d91.s215
sentences.origID: 49
sentences.text: Oxytocin-stimulated insulin release in a clonal beta-cell line RINm5F: involvement of phospholipase C-dependent and -independent pathways.
sentences.id: IEPA.d91.s215.e0
sentences.origID: 114
sentences.text: insulin
sentences.id: IEPA.d91.s215.e1
sentences.origID: 115
sentences.text: phospholipase C
sentences.id: IEPA.d91.s215.i0
sentences.e1: IEPA.d91.s215.e0
sentences.e2: IEPA.d91.s215.e1
sentences.type: PPI
sentences.id: IEPA.d91.s216
sentences.origID: 50
sentences.text: CONCLUSION: Oxy increases insulin release through both PLC and non-PLC mediated signal transduction mechanisms.
sentences.id: IEPA.d91.s216.e0
sentences.origID: 116
sentences.text: insulin
sentences.id: IEPA.d91.s216.e1
sentences.origID: 117
sentences.text: PLC
sentences.id: IEPA.d91.s216.i0
sentences.e1: IEPA.d91.s216.e0
sentences.e2: IEPA.d91.s216.e1
sentences.type: PPI
sentences.id: IEPA.d91.s217
sentences.origID: 379
sentences.text: In addition, U-73122 diminished the Oxy-induced increase in intracellular concentration of inositol 1, 4, 5-triphosphate (IP3)
sentences.id: IEPA.d91.s217.e0
sentences.origID: 865
sentences.text: Oxy
sentences.id: IEPA.d91.s217.e1
sentences.origID: 866
sentences.text: inositol 1, 4, 5-triphosphate
sentences.id: IEPA.d91.s217.i0
sentences.e1: IEPA.d91.s217.e0
sentences.e2: IEPA.d91.s217.e1
sentences.type: PPI
sentences.id: IEPA.d91.s218
sentences.origID: 380
sentences.text: U-73122 at 8 mumol.L-1 totally abolished the Oxy-induced increases in [Ca2+]i and IP3; however it reduced the Oxy-induced increase in insulin release only by 36% and 63% in the monolayer and suspended cell preparations, respectively
sentences.id: IEPA.d91.s218.e0
sentences.origID: 867
sentences.text: Oxy
sentences.id: IEPA.d91.s218.e1
sentences.origID: 868
sentences.text: IP3
sentences.id: IEPA.d91.s218.e2
sentences.origID: 869
sentences.text: Oxy
sentences.id: IEPA.d91.s218.i0
sentences.e1: IEPA.d91.s218.e0
sentences.e2: IEPA.d91.s218.e1
sentences.type: PPI
sentences.id: IEPA.d91.s219
sentences.origID: 451
sentences.text: Oxytocin-stimulated insulin release in a clonal beta-cell line RINm5F: involvement of phospholipase C-dependent and -independent pathways
sentences.id: IEPA.d91.s219.e0
sentences.origID: 1017
sentences.text: Oxytocin
sentences.id: IEPA.d91.s219.e1
sentences.origID: 1018
sentences.text: insulin
sentences.id: IEPA.d91.s219.i0
sentences.e1: IEPA.d91.s219.e0
sentences.e2: IEPA.d91.s219.e1
sentences.type: PPI
sentences.id: IEPA.d91.s220
sentences.origID: 452
sentences.text: AIM: To study the mechanisms underlying oxytocin (Oxy)-induced insulin release
sentences.id: IEPA.d91.s220.e0
sentences.origID: 1019
sentences.text: oxytocin
sentences.id: IEPA.d91.s220.e1
sentences.origID: 1020
sentences.text: insulin
sentences.id: IEPA.d91.s220.i0
sentences.e1: IEPA.d91.s220.e0
sentences.e2: IEPA.d91.s220.e1
sentences.type: PPI
sentences.id: IEPA.d91.s221
sentences.origID: 453
sentences.text: RESULTS: Oxy increased insulin release and [Ca2+]i in a concentration-dependent manner
sentences.id: IEPA.d91.s221.e0
sentences.origID: 1021
sentences.text: Oxy
sentences.id: IEPA.d91.s221.e1
sentences.origID: 1022
sentences.text: insulin
sentences.id: IEPA.d91.s221.i0
sentences.e1: IEPA.d91.s221.e0
sentences.e2: IEPA.d91.s221.e1
sentences.type: PPI
sentences.id: IEPA.d91.s222
sentences.origID: 454
sentences.text: Oxy-induced insulin release was not altered by pretreatment with pertussis toxin (PT)
sentences.id: IEPA.d91.s222.e0
sentences.origID: 1023
sentences.text: Oxy
sentences.id: IEPA.d91.s222.e1
sentences.origID: 1024
sentences.text: insulin
sentences.id: IEPA.d91.s222.i0
sentences.e1: IEPA.d91.s222.e0
sentences.e2: IEPA.d91.s222.e1
sentences.type: PPI
sentences.id: IEPA.d91.s223
sentences.origID: 455
sentences.text: U-73122 at 8 mumol.L-1 totally abolished the Oxy-induced increases in [Ca2+]i and IP3; however it reduced the Oxy-induced increase in insulin release only by 36% and 63% in the monolayer and suspended cell preparations, respectively
sentences.id: IEPA.d91.s223.e0
sentences.origID: 1025
sentences.text: Oxy
sentences.id: IEPA.d91.s223.e1
sentences.origID: 1026
sentences.text: Oxy
sentences.id: IEPA.d91.s223.e2
sentences.origID: 1027
sentences.text: insulin
sentences.id: IEPA.d91.s223.i0
sentences.e1: IEPA.d91.s223.e1
sentences.e2: IEPA.d91.s223.e2
sentences.type: PPI
sentences.id: IEPA.d91.s224
sentences.origID: 456
sentences.text: CONCLUSION: Oxy increases insulin release through both PLC and non-PLC mediated signal transduction mechanisms
sentences.id: IEPA.d91.s224.e0
sentences.origID: 1028
sentences.text: Oxy
sentences.id: IEPA.d91.s224.e1
sentences.origID: 1029
sentences.text: insulin
sentences.id: IEPA.d91.s224.i0
sentences.e1: IEPA.d91.s224.e0
sentences.e2: IEPA.d91.s224.e1
sentences.type: PPI