sentences.id: IEPA.d168.s404
sentences.origID: 301
sentences.text: Involvement of thyroid hormones in the effect of intracerebroventricular leptin infusion on uncoupling protein-3 expression in rat muscle
sentences.id: IEPA.d168.s404.e0
sentences.origID: 658
sentences.text: leptin
sentences.id: IEPA.d168.s404.e1
sentences.origID: 659
sentences.text: uncoupling protein-3
sentences.id: IEPA.d168.s404.i0
sentences.e1: IEPA.d168.s404.e0
sentences.e2: IEPA.d168.s404.e1
sentences.type: PPI
sentences.id: IEPA.d168.s405
sentences.origID: 302
sentences.text: A reduction of food intake imposed on control rats (pair-feeding), aimed at mimicking leptin-induced hyperphagia, produced a marked decrease in the expression of muscle uncoupling protein-3 (UCP-3), whereas ICV infusion of leptin prevented such a decrease in UCP-3
sentences.id: IEPA.d168.s405.e0
sentences.origID: 660
sentences.text: leptin
sentences.id: IEPA.d168.s405.e1
sentences.origID: 661
sentences.text: uncoupling protein-3
sentences.id: IEPA.d168.s405.e2
sentences.origID: 662
sentences.text: leptin
sentences.id: IEPA.d168.s405.e3
sentences.origID: 663
sentences.text: UCP-3
sentences.id: IEPA.d168.s405.i0
sentences.e1: IEPA.d168.s405.e0
sentences.e2: IEPA.d168.s405.e1
sentences.type: PPI
sentences.id: IEPA.d168.s405.i1
sentences.e1: IEPA.d168.s405.e2
sentences.e2: IEPA.d168.s405.e3
sentences.type: PPI
sentences.id: IEPA.d168.s406
sentences.origID: 303
sentences.text: To further substantiate an involvement of thyroid hormones in the effect of leptin on muscle UCP-3 expression, hypothyroid rats were ICV infused with leptin or vehicle
sentences.id: IEPA.d168.s406.e0
sentences.origID: 664
sentences.text: leptin
sentences.id: IEPA.d168.s406.e1
sentences.origID: 665
sentences.text: UCP-3
sentences.id: IEPA.d168.s406.e2
sentences.origID: 666
sentences.text: leptin
sentences.id: IEPA.d168.s406.i0
sentences.e1: IEPA.d168.s406.e0
sentences.e2: IEPA.d168.s406.e1
sentences.type: PPI
sentences.id: IEPA.d168.s407
sentences.origID: 304
sentences.text: It was observed that in hypothyroid rats, ICV leptin was unable to maintain muscle UCP-3 expression at values measured in ad libitum fed controls
sentences.id: IEPA.d168.s407.e0
sentences.origID: 667
sentences.text: leptin
sentences.id: IEPA.d168.s407.e1
sentences.origID: 668
sentences.text: UCP-3
sentences.id: IEPA.d168.s407.i0
sentences.e1: IEPA.d168.s407.e0
sentences.e2: IEPA.d168.s407.e1
sentences.type: PPI
sentences.id: IEPA.d168.s408
sentences.origID: 305
sentences.text: These results suggest that central leptin stimulates T3 production via an activation of T4 to T3 conversion, and that this stimulation could be responsible for the effect of leptin on muscle UCP-3 expression
sentences.id: IEPA.d168.s408.e0
sentences.origID: 669
sentences.text: leptin
sentences.id: IEPA.d168.s408.e1
sentences.origID: 670
sentences.text: leptin
sentences.id: IEPA.d168.s408.e2
sentences.origID: 671
sentences.text: UCP-3
sentences.id: IEPA.d168.s408.i0
sentences.e1: IEPA.d168.s408.e1
sentences.e2: IEPA.d168.s408.e2
sentences.type: PPI