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DS.d828
18712272
[ { "id": "DS.d828.s0", "type": "", "text": [ "We used this model to identify a potent competitive inhibitor, N1,N7-dihexyl-1,7-diamino-4-azaheptane, and to develop an affinity column, 1,16-diamino4,13-diazahexadecane-linked Sepharose, which was useful for the purification of PAO." ], "offsets": [ [ 0, 234 ] ] } ]
[ { "id": "DS.d828.s0.e0", "type": "compound", "text": [ "Sepharose" ], "offsets": [ [ 178, 187 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "11966311" } ] }, { "id": "DS.d828.s0.e1", "type": "protein", "text": [ "PAO" ], "offsets": [ [ 230, 233 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O64411" }, { "db_name": "UniProt", "db_id": "Q6QHF9" }, { "db_name": "UniProt", "db_id": "Q865R1" }, { "db_name": "UniProt", "db_id": "Q9FYC2" } ] } ]
[]
[]
[ { "id": "DS.d828.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d828.s0.e0", "arg2_id": "DS.d828.s0.e1", "normalized": [] } ]
DS.d829
18712288
[ { "id": "DS.d829.s0", "type": "", "text": [ "Rapid determination of L-glutamine using engineered Escherichia coli overexpressing glutamine synthetase." ], "offsets": [ [ 0, 105 ] ] } ]
[ { "id": "DS.d829.s0.e0", "type": "compound", "text": [ "L-glutamine" ], "offsets": [ [ 23, 34 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5961" }, { "db_name": "PubChem", "db_id": "145815" } ] }, { "id": "DS.d829.s0.e1", "type": "protein", "text": [ "glutamine synthetase" ], "offsets": [ [ 84, 104 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O00088" }, { "db_name": "UniProt", "db_id": "O04867" }, { "db_name": "UniProt", "db_id": "O08467" }, { "db_name": "UniProt", "db_id": "O27612" }, { "db_name": "UniProt", "db_id": "O29313" }, { "db_name": "UniProt", "db_id": "O58097" }, { "db_name": "UniProt", "db_id": "O59648" }, { "db_name": "UniProt", "db_id": "O66514" }, { "db_name": "UniProt", "db_id": "P00964" }, { "db_name": "UniProt", "db_id": "P04773" }, { "db_name": "UniProt", "db_id": "P07804" }, { "db_name": "UniProt", "db_id": "P09606" }, { "db_name": "UniProt", "db_id": "P0A039" }, { "db_name": "UniProt", "db_id": "P0A040" }, { "db_name": "UniProt", "db_id": "P0A1P6" }, { "db_name": "UniProt", "db_id": "P0A1P7" }, { "db_name": "UniProt", "db_id": "P0A9C5" }, { "db_name": "UniProt", "db_id": "P0A9C6" }, { "db_name": "UniProt", "db_id": "P0A9C7" }, { "db_name": "UniProt", "db_id": "P0A9C8" }, { "db_name": "UniProt", "db_id": "P10583" }, { "db_name": "UniProt", "db_id": "P10656" }, { "db_name": "UniProt", "db_id": "P11600" }, { "db_name": "UniProt", "db_id": "P12424" }, { "db_name": "UniProt", "db_id": "P12425" }, { "db_name": "UniProt", "db_id": "P13499" }, { "db_name": "UniProt", "db_id": "P15103" }, { "db_name": "UniProt", "db_id": "P15104" }, { "db_name": "UniProt", "db_id": "P15105" }, { "db_name": "UniProt", "db_id": "P15106" }, { "db_name": "UniProt", "db_id": "P15124" }, { "db_name": "UniProt", "db_id": "P15623" }, { "db_name": "UniProt", "db_id": "P16580" }, { "db_name": "UniProt", "db_id": "P19064" }, { "db_name": "UniProt", "db_id": "P19904" }, { "db_name": "UniProt", "db_id": "P20479" }, { "db_name": "UniProt", "db_id": "P21154" }, { "db_name": "UniProt", "db_id": "P22248" }, { "db_name": "UniProt", "db_id": "P23712" }, { "db_name": "UniProt", "db_id": "P23794" }, { "db_name": "UniProt", "db_id": "P25821" }, { "db_name": "UniProt", "db_id": "P28605" }, { "db_name": "UniProt", "db_id": "P28786" }, { "db_name": "UniProt", "db_id": "P32288" }, { "db_name": "UniProt", "db_id": "P33035" }, { "db_name": "UniProt", "db_id": "P36205" }, { "db_name": "UniProt", "db_id": "P43386" }, { "db_name": "UniProt", "db_id": "P43518" }, { "db_name": "UniProt", "db_id": "P43794" }, { "db_name": "UniProt", "db_id": "P45627" }, { "db_name": "UniProt", "db_id": "P46410" }, { "db_name": "UniProt", "db_id": "P51120" }, { "db_name": "UniProt", "db_id": "P51121" }, { "db_name": "UniProt", "db_id": "P60890" }, { "db_name": "UniProt", "db_id": "P77961" }, { "db_name": "UniProt", "db_id": "P94126" }, { "db_name": "UniProt", "db_id": "P94845" }, { "db_name": "UniProt", "db_id": "P99095" }, { "db_name": "UniProt", "db_id": "Q04831" }, { "db_name": "UniProt", "db_id": "Q05650" }, { "db_name": "UniProt", "db_id": "Q05907" }, { "db_name": "UniProt", "db_id": "Q06378" }, { "db_name": "UniProt", "db_id": "Q09179" }, { "db_name": "UniProt", "db_id": "Q12613" }, { "db_name": "UniProt", "db_id": "Q4R7U3" }, { "db_name": "UniProt", "db_id": "Q5HGC3" }, { "db_name": "UniProt", "db_id": "Q5HPN2" }, { "db_name": "UniProt", "db_id": "Q60182" }, { "db_name": "UniProt", "db_id": "Q6B4U7" }, { "db_name": "UniProt", "db_id": "Q6C3E0" }, { "db_name": "UniProt", "db_id": "Q6FMT6" }, { "db_name": "UniProt", "db_id": "Q6G9Q4" }, { "db_name": "UniProt", "db_id": "Q6GHC6" }, { "db_name": "UniProt", "db_id": "Q75BT9" }, { "db_name": "UniProt", "db_id": "Q86ZF9" }, { "db_name": "UniProt", "db_id": "Q86ZU6" }, { "db_name": "UniProt", "db_id": "Q874T6" }, { "db_name": "UniProt", "db_id": "Q8CSR8" }, { "db_name": "UniProt", "db_id": "Q8HZM5" }, { "db_name": "UniProt", "db_id": "Q8J1R3" }, { "db_name": "UniProt", "db_id": "Q8X169" }, { "db_name": "UniProt", "db_id": "Q96UG9" }, { "db_name": "UniProt", "db_id": "Q96UV5" }, { "db_name": "UniProt", "db_id": "Q96V52" }, { "db_name": "UniProt", "db_id": "Q9C2U9" }, { "db_name": "UniProt", "db_id": "Q9CDL9" }, { "db_name": "UniProt", "db_id": "Q9CLP2" }, { "db_name": "UniProt", "db_id": "Q9HH09" }, { "db_name": "UniProt", "db_id": "Q9HNI2" }, { "db_name": "UniProt", "db_id": "Q9HU65" }, { "db_name": "UniProt", "db_id": "Q9KNJ2" }, { "db_name": "UniProt", "db_id": "Q9QY94" }, { "db_name": "UniProt", "db_id": "Q9UUN6" }, { "db_name": "UniProt", "db_id": "Q9UY99" }, { "db_name": "UniProt", "db_id": "Q9ZLW5" } ] } ]
[]
[]
[ { "id": "DS.d829.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d829.s0.e0", "arg2_id": "DS.d829.s0.e1", "normalized": [] } ]
DS.d830
18712290
[ { "id": "DS.d830.s0", "type": "", "text": [ "Purification, characterization, and preliminary X-ray diffraction analysis of a lactose-specific lectin from Cymbosema roseum seeds." ], "offsets": [ [ 0, 132 ] ] }, { "id": "DS.d830.s1", "type": "", "text": [ "Here, we report the purification, partial primary structure, carbohydrate affinity characterization, crystallization, and preliminary X-ray diffraction analysis of a lactose-specific lectin from Cymbosema roseum seeds (CRLII)." ], "offsets": [ [ 133, 359 ] ] } ]
[ { "id": "DS.d830.s0.e0", "type": "compound", "text": [ "lactose" ], "offsets": [ [ 80, 87 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "294" }, { "db_name": "PubChem", "db_id": "6134" }, { "db_name": "PubChem", "db_id": "84571" }, { "db_name": "PubChem", "db_id": "440995" } ] }, { "id": "DS.d830.s0.e1", "type": "protein", "text": [ "lectin" ], "offsets": [ [ 97, 103 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02871" }, { "db_name": "UniProt", "db_id": "P02873" }, { "db_name": "UniProt", "db_id": "P02874" }, { "db_name": "UniProt", "db_id": "P02875" }, { "db_name": "UniProt", "db_id": "P07386" }, { "db_name": "UniProt", "db_id": "P16108" }, { "db_name": "UniProt", "db_id": "P16349" }, { "db_name": "UniProt", "db_id": "P16351" }, { "db_name": "UniProt", "db_id": "P16352" }, { "db_name": "UniProt", "db_id": "P33888" }, { "db_name": "UniProt", "db_id": "P38662" }, { "db_name": "UniProt", "db_id": "P42088" }, { "db_name": "UniProt", "db_id": "P83410" }, { "db_name": "UniProt", "db_id": "P83511" }, { "db_name": "UniProt", "db_id": "P84987" }, { "db_name": "UniProt", "db_id": "Q41114" } ] }, { "id": "DS.d830.s1.e0", "type": "compound", "text": [ "lactose" ], "offsets": [ [ 299, 306 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "294" }, { "db_name": "PubChem", "db_id": "6134" }, { "db_name": "PubChem", "db_id": "84571" }, { "db_name": "PubChem", "db_id": "440995" } ] }, { "id": "DS.d830.s1.e1", "type": "protein", "text": [ "lectin" ], "offsets": [ [ 316, 322 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02871" }, { "db_name": "UniProt", "db_id": "P02873" }, { "db_name": "UniProt", "db_id": "P02874" }, { "db_name": "UniProt", "db_id": "P02875" }, { "db_name": "UniProt", "db_id": "P07386" }, { "db_name": "UniProt", "db_id": "P16108" }, { "db_name": "UniProt", "db_id": "P16349" }, { "db_name": "UniProt", "db_id": "P16351" }, { "db_name": "UniProt", "db_id": "P16352" }, { "db_name": "UniProt", "db_id": "P33888" }, { "db_name": "UniProt", "db_id": "P38662" }, { "db_name": "UniProt", "db_id": "P42088" }, { "db_name": "UniProt", "db_id": "P83410" }, { "db_name": "UniProt", "db_id": "P83511" }, { "db_name": "UniProt", "db_id": "P84987" }, { "db_name": "UniProt", "db_id": "Q41114" } ] } ]
[]
[]
[ { "id": "DS.d830.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d830.s0.e0", "arg2_id": "DS.d830.s0.e1", "normalized": [] }, { "id": "DS.d830.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d830.s1.e0", "arg2_id": "DS.d830.s1.e1", "normalized": [] } ]
DS.d831
18712361
[ { "id": "DS.d831.s0", "type": "", "text": [ "Effects on haemolytic activity of single proline substitutions in the Bordetella pertussis CyaA pore-forming fragment." ], "offsets": [ [ 0, 118 ] ] } ]
[ { "id": "DS.d831.s0.e0", "type": "compound", "text": [ "proline" ], "offsets": [ [ 41, 48 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "614" }, { "db_name": "PubChem", "db_id": "8988" }, { "db_name": "PubChem", "db_id": "145742" } ] }, { "id": "DS.d831.s0.e1", "type": "protein", "text": [ "CyaA" ], "offsets": [ [ 91, 95 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P00936" }, { "db_name": "UniProt", "db_id": "P0A1A7" }, { "db_name": "UniProt", "db_id": "P0A1A8" }, { "db_name": "UniProt", "db_id": "P15318" }, { "db_name": "UniProt", "db_id": "P19485" }, { "db_name": "UniProt", "db_id": "P40127" }, { "db_name": "UniProt", "db_id": "P40134" }, { "db_name": "UniProt", "db_id": "P40137" }, { "db_name": "UniProt", "db_id": "P59739" }, { "db_name": "UniProt", "db_id": "P98009" }, { "db_name": "UniProt", "db_id": "Q57506" }, { "db_name": "UniProt", "db_id": "Q8FBP0" }, { "db_name": "UniProt", "db_id": "Q8XAP1" }, { "db_name": "UniProt", "db_id": "Q9WXC3" } ] } ]
[]
[]
[ { "id": "DS.d831.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d831.s0.e0", "arg2_id": "DS.d831.s0.e1", "normalized": [] } ]
DS.d832
18712381
[ { "id": "DS.d832.s0", "type": "", "text": [ "Associations between the uptake of 111In-DTPA-trastuzumab, HER2 density and response to trastuzumab (Herceptin) in athymic mice bearing subcutaneous human tumour xenografts." ], "offsets": [ [ 0, 173 ] ] }, { "id": "DS.d832.s1", "type": "", "text": [ "The purpose of the study was to investigate the associations between uptake of (111)In-DTPA-trastuzumab, tumour HER2 density and response to trastuzumab (Herceptin) of human breast cancer (BC) xenografts in athymic mice." ], "offsets": [ [ 174, 394 ] ] } ]
[ { "id": "DS.d832.s0.e0", "type": "compound", "text": [ "DTPA" ], "offsets": [ [ 41, 45 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "3053" } ] }, { "id": "DS.d832.s0.e1", "type": "protein", "text": [ "HER2" ], "offsets": [ [ 59, 63 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P04626" } ] }, { "id": "DS.d832.s1.e0", "type": "compound", "text": [ "DTPA" ], "offsets": [ [ 261, 265 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "3053" } ] }, { "id": "DS.d832.s1.e1", "type": "protein", "text": [ "HER2" ], "offsets": [ [ 286, 290 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P04626" } ] } ]
[]
[]
[ { "id": "DS.d832.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d832.s0.e0", "arg2_id": "DS.d832.s0.e1", "normalized": [] }, { "id": "DS.d832.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d832.s1.e0", "arg2_id": "DS.d832.s1.e1", "normalized": [] } ]
DS.d833
18712598
[ { "id": "DS.d833.s0", "type": "", "text": [ "The adenosine (the final product of ATP hydrolysis by ectonucleotidases), have a recognized neuroprotective actions in the central nervous system (CNS) in pathological conditions." ], "offsets": [ [ 0, 179 ] ] } ]
[ { "id": "DS.d833.s0.e0", "type": "compound", "text": [ "adenosine" ], "offsets": [ [ 4, 13 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "60961" } ] }, { "id": "DS.d833.s0.e1", "type": "protein", "text": [ "ectonucleotidases" ], "offsets": [ [ 54, 71 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P29240" } ] } ]
[]
[]
[ { "id": "DS.d833.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d833.s0.e0", "arg2_id": "DS.d833.s0.e1", "normalized": [] } ]
DS.d834
18712838
[ { "id": "DS.d834.s0", "type": "", "text": [ "To this end, the cultured fibroblasts were analyzed for very long chain fatty acid (VLCFA) concentrations, peroxisomal beta- and alpha-oxidation, dihydroxyacetone-phosphate acyltransferase (DHAPAT) activity, peroxisomal thiolase, and catalase immunofluorescence." ], "offsets": [ [ 0, 262 ] ] } ]
[ { "id": "DS.d834.s0.e0", "type": "compound", "text": [ "long chain fatty acid" ], "offsets": [ [ 61, 82 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "284" } ] }, { "id": "DS.d834.s0.e1", "type": "protein", "text": [ "dihydroxyacetone-phosphate acyltransferase" ], "offsets": [ [ 146, 188 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O15228" }, { "db_name": "UniProt", "db_id": "P98192" }, { "db_name": "UniProt", "db_id": "Q9ES71" } ] }, { "id": "DS.d834.s0.e2", "type": "protein", "text": [ "DHAPAT" ], "offsets": [ [ 190, 196 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O15228" } ] }, { "id": "DS.d834.s0.e3", "type": "protein", "text": [ "thiolase" ], "offsets": [ [ 220, 228 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q6L8K7" } ] }, { "id": "DS.d834.s0.e4", "type": "protein", "text": [ "catalase" ], "offsets": [ [ 234, 242 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O24339" }, { "db_name": "UniProt", "db_id": "O52762" }, { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O68146" }, { "db_name": "UniProt", "db_id": "O77229" }, { "db_name": "UniProt", "db_id": "O93662" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P04762" }, { "db_name": "UniProt", "db_id": "P07145" }, { "db_name": "UniProt", "db_id": "P0A323" }, { "db_name": "UniProt", "db_id": "P0A324" }, { "db_name": "UniProt", "db_id": "P0A325" }, { "db_name": "UniProt", "db_id": "P0A326" }, { "db_name": "UniProt", "db_id": "P0A327" }, { "db_name": "UniProt", "db_id": "P11934" }, { "db_name": "UniProt", "db_id": "P17336" }, { "db_name": "UniProt", "db_id": "P24168" }, { "db_name": "UniProt", "db_id": "P24270" }, { "db_name": "UniProt", "db_id": "P25890" }, { "db_name": "UniProt", "db_id": "P29422" }, { "db_name": "UniProt", "db_id": "P30265" }, { "db_name": "UniProt", "db_id": "P30266" }, { "db_name": "UniProt", "db_id": "P32290" }, { "db_name": "UniProt", "db_id": "P42321" }, { "db_name": "UniProt", "db_id": "P44390" }, { "db_name": "UniProt", "db_id": "P45737" }, { "db_name": "UniProt", "db_id": "P45739" }, { "db_name": "UniProt", "db_id": "P55304" }, { "db_name": "UniProt", "db_id": "P55306" }, { "db_name": "UniProt", "db_id": "P55310" }, { "db_name": "UniProt", "db_id": "P55311" }, { "db_name": "UniProt", "db_id": "P55313" }, { "db_name": "UniProt", "db_id": "P77872" }, { "db_name": "UniProt", "db_id": "P81138" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q27710" }, { "db_name": "UniProt", "db_id": "Q49XC1" }, { "db_name": "UniProt", "db_id": "Q4L643" }, { "db_name": "UniProt", "db_id": "Q59296" }, { "db_name": "UniProt", "db_id": "Q59337" }, { "db_name": "UniProt", "db_id": "Q59602" }, { "db_name": "UniProt", "db_id": "Q59714" }, { "db_name": "UniProt", "db_id": "Q5HG86" }, { "db_name": "UniProt", "db_id": "Q5HPK8" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q6G9M4" }, { "db_name": "UniProt", "db_id": "Q6GH72" }, { "db_name": "UniProt", "db_id": "Q7A5T2" }, { "db_name": "UniProt", "db_id": "Q8CPD0" }, { "db_name": "UniProt", "db_id": "Q8FWU0" }, { "db_name": "UniProt", "db_id": "Q8NWV5" }, { "db_name": "UniProt", "db_id": "Q8X1P0" }, { "db_name": "UniProt", "db_id": "Q8Y3P9" }, { "db_name": "UniProt", "db_id": "Q926X0" }, { "db_name": "UniProt", "db_id": "Q99UE2" }, { "db_name": "UniProt", "db_id": "Q9AXH0" }, { "db_name": "UniProt", "db_id": "Q9KW19" }, { "db_name": "UniProt", "db_id": "Q9L4S1" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PT92" }, { "db_name": "UniProt", "db_id": "Q9PWF7" }, { "db_name": "UniProt", "db_id": "Q9Z598" }, { "db_name": "UniProt", "db_id": "Q9ZKX5" }, { "db_name": "UniProt", "db_id": "Q9ZN99" } ] } ]
[]
[]
[]
DS.d835
18713274
[ { "id": "DS.d835.s0", "type": "", "text": [ "Also, iNOS induction and concomitant nitric oxide generation appear to participate in the cytotoxicity of excessive portal pressure after extended hepatectomy." ], "offsets": [ [ 0, 159 ] ] } ]
[ { "id": "DS.d835.s0.e0", "type": "protein", "text": [ "iNOS" ], "offsets": [ [ 6, 10 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O19114" }, { "db_name": "UniProt", "db_id": "O46660" }, { "db_name": "UniProt", "db_id": "O54705" }, { "db_name": "UniProt", "db_id": "O62699" }, { "db_name": "UniProt", "db_id": "P29477" }, { "db_name": "UniProt", "db_id": "P35228" }, { "db_name": "UniProt", "db_id": "P79290" }, { "db_name": "UniProt", "db_id": "Q06518" }, { "db_name": "UniProt", "db_id": "Q27995" }, { "db_name": "UniProt", "db_id": "Q28314" }, { "db_name": "UniProt", "db_id": "Q90703" }, { "db_name": "UniProt", "db_id": "Q92037" }, { "db_name": "UniProt", "db_id": "Q92091" } ] }, { "id": "DS.d835.s0.e1", "type": "compound", "text": [ "nitric oxide" ], "offsets": [ [ 37, 49 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "145068" } ] } ]
[]
[]
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DS.d836
18713277
[ { "id": "DS.d836.s0", "type": "", "text": [ "Superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), catalase (CAT) enzyme activities, antioxidant potential (AOP) value, malondialdehyde (MDA), cholesterol and triglyceride levels in the liver tissues and total cholesterol and triglyceride levels in serum samples were measured." ], "offsets": [ [ 0, 287 ] ] } ]
[ { "id": "DS.d836.s0.e0", "type": "protein", "text": [ "Superoxide dismutase" ], "offsets": [ [ 0, 20 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O50258" } ] }, { "id": "DS.d836.s0.e1", "type": "protein", "text": [ "SOD" ], "offsets": [ [ 22, 25 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12933" }, { "db_name": "UniProt", "db_id": "O22668" }, { "db_name": "UniProt", "db_id": "O75007" }, { "db_name": "UniProt", "db_id": "P24705" }, { "db_name": "UniProt", "db_id": "P51547" }, { "db_name": "UniProt", "db_id": "P93258" }, { "db_name": "UniProt", "db_id": "Q01137" }, { "db_name": "UniProt", "db_id": "Q27666" }, { "db_name": "UniProt", "db_id": "Q9SM64" } ] }, { "id": "DS.d836.s0.e2", "type": "protein", "text": [ "glutathione peroxidase" ], "offsets": [ [ 28, 50 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O32770" }, { "db_name": "UniProt", "db_id": "O59858" }, { "db_name": "UniProt", "db_id": "Q00277" }, { "db_name": "UniProt", "db_id": "Q9CFV1" } ] }, { "id": "DS.d836.s0.e3", "type": "protein", "text": [ "catalase" ], "offsets": [ [ 61, 69 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O24339" }, { "db_name": "UniProt", "db_id": "O52762" }, { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O68146" }, { "db_name": "UniProt", "db_id": "O77229" }, { "db_name": "UniProt", "db_id": "O93662" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P04762" }, { "db_name": "UniProt", "db_id": "P07145" }, { "db_name": "UniProt", "db_id": "P0A323" }, { "db_name": "UniProt", "db_id": "P0A324" }, { "db_name": "UniProt", "db_id": "P0A325" }, { "db_name": "UniProt", "db_id": "P0A326" }, { "db_name": "UniProt", "db_id": "P0A327" }, { "db_name": "UniProt", "db_id": "P11934" }, { "db_name": "UniProt", "db_id": "P17336" }, { "db_name": "UniProt", "db_id": "P24168" }, { "db_name": "UniProt", "db_id": "P24270" }, { "db_name": "UniProt", "db_id": "P25890" }, { "db_name": "UniProt", "db_id": "P29422" }, { "db_name": "UniProt", "db_id": "P30265" }, { "db_name": "UniProt", "db_id": "P30266" }, { "db_name": "UniProt", "db_id": "P32290" }, { "db_name": "UniProt", "db_id": "P42321" }, { "db_name": "UniProt", "db_id": "P44390" }, { "db_name": "UniProt", "db_id": "P45737" }, { "db_name": "UniProt", "db_id": "P45739" }, { "db_name": "UniProt", "db_id": "P55304" }, { "db_name": "UniProt", "db_id": "P55306" }, { "db_name": "UniProt", "db_id": "P55310" }, { "db_name": "UniProt", "db_id": "P55311" }, { "db_name": "UniProt", "db_id": "P55313" }, { "db_name": "UniProt", "db_id": "P77872" }, { "db_name": "UniProt", "db_id": "P81138" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q27710" }, { "db_name": "UniProt", "db_id": "Q49XC1" }, { "db_name": "UniProt", "db_id": "Q4L643" }, { "db_name": "UniProt", "db_id": "Q59296" }, { "db_name": "UniProt", "db_id": "Q59337" }, { "db_name": "UniProt", "db_id": "Q59602" }, { "db_name": "UniProt", "db_id": "Q59714" }, { "db_name": "UniProt", "db_id": "Q5HG86" }, { "db_name": "UniProt", "db_id": "Q5HPK8" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q6G9M4" }, { "db_name": "UniProt", "db_id": "Q6GH72" }, { "db_name": "UniProt", "db_id": "Q7A5T2" }, { "db_name": "UniProt", "db_id": "Q8CPD0" }, { "db_name": "UniProt", "db_id": "Q8FWU0" }, { "db_name": "UniProt", "db_id": "Q8NWV5" }, { "db_name": "UniProt", "db_id": "Q8X1P0" }, { "db_name": "UniProt", "db_id": "Q8Y3P9" }, { "db_name": "UniProt", "db_id": "Q926X0" }, { "db_name": "UniProt", "db_id": "Q99UE2" }, { "db_name": "UniProt", "db_id": "Q9AXH0" }, { "db_name": "UniProt", "db_id": "Q9KW19" }, { "db_name": "UniProt", "db_id": "Q9L4S1" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PT92" }, { "db_name": "UniProt", "db_id": "Q9PWF7" }, { "db_name": "UniProt", "db_id": "Q9Z598" }, { "db_name": "UniProt", "db_id": "Q9ZKX5" }, { "db_name": "UniProt", "db_id": "Q9ZN99" } ] }, { "id": "DS.d836.s0.e4", "type": "protein", "text": [ "CAT" ], "offsets": [ [ 71, 74 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P00485" }, { "db_name": "UniProt", "db_id": "P00486" }, { "db_name": "UniProt", "db_id": "P00487" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P06135" }, { "db_name": "UniProt", "db_id": "P07641" }, { "db_name": "UniProt", "db_id": "P11504" }, { "db_name": "UniProt", "db_id": "P20074" }, { "db_name": "UniProt", "db_id": "P22782" }, { "db_name": "UniProt", "db_id": "P25309" }, { "db_name": "UniProt", "db_id": "P25819" }, { "db_name": "UniProt", "db_id": "P26825" }, { "db_name": "UniProt", "db_id": "P26826" }, { "db_name": "UniProt", "db_id": "P32796" }, { "db_name": "UniProt", "db_id": "P36882" }, { "db_name": "UniProt", "db_id": "P36883" }, { "db_name": "UniProt", "db_id": "P43155" }, { "db_name": "UniProt", "db_id": "P47934" }, { "db_name": "UniProt", "db_id": "P49417" }, { "db_name": "UniProt", "db_id": "P52826" }, { "db_name": "UniProt", "db_id": "P58777" }, { "db_name": "UniProt", "db_id": "P62577" }, { "db_name": "UniProt", "db_id": "P62578" }, { "db_name": "UniProt", "db_id": "P62579" }, { "db_name": "UniProt", "db_id": "P62580" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q00614" }, { "db_name": "UniProt", "db_id": "Q02736" }, { "db_name": "UniProt", "db_id": "Q03058" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q704S8" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PWF7" } ] }, { "id": "DS.d836.s0.e5", "type": "compound", "text": [ "malondialdehyde" ], "offsets": [ [ 130, 145 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "10964" } ] }, { "id": "DS.d836.s0.e6", "type": "compound", "text": [ "cholesterol" ], "offsets": [ [ 153, 164 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "304" }, { "db_name": "PubChem", "db_id": "5997" }, { "db_name": "PubChem", "db_id": "6432564" }, { "db_name": "PubChem", "db_id": "11025495" } ] }, { "id": "DS.d836.s0.e7", "type": "compound", "text": [ "cholesterol" ], "offsets": [ [ 220, 231 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "304" }, { "db_name": "PubChem", "db_id": "5997" }, { "db_name": "PubChem", "db_id": "6432564" }, { "db_name": "PubChem", "db_id": "11025495" } ] } ]
[]
[]
[]
DS.d837
18714161
[ { "id": "DS.d837.s0", "type": "", "text": [ "Inhibition of apoptotic signaling and neointimal hyperplasia by tempol and nitric oxide synthase following vascular injury." ], "offsets": [ [ 0, 123 ] ] } ]
[ { "id": "DS.d837.s0.e0", "type": "compound", "text": [ "tempol" ], "offsets": [ [ 64, 70 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "137994" } ] }, { "id": "DS.d837.s0.e1", "type": "protein", "text": [ "nitric oxide synthase" ], "offsets": [ [ 75, 96 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O61309" }, { "db_name": "UniProt", "db_id": "O61608" }, { "db_name": "UniProt", "db_id": "Q27571" }, { "db_name": "UniProt", "db_id": "Q9I9M2" } ] } ]
[]
[]
[ { "id": "DS.d837.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d837.s0.e0", "arg2_id": "DS.d837.s0.e1", "normalized": [] } ]
DS.d838
18715145
[ { "id": "DS.d838.s0", "type": "", "text": [ "Forced cytoplasmic overexpression of APE1 profoundly attenuated the upregulation of HMGB1-mediated reactive oxygen species generation, cytokine secretion, and cyclooxygenase-2 expression by primary monocytes and macrophage-like THP-1 cell lines." ], "offsets": [ [ 0, 245 ] ] } ]
[ { "id": "DS.d838.s0.e0", "type": "protein", "text": [ "APE1" ], "offsets": [ [ 37, 41 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P14904" } ] }, { "id": "DS.d838.s0.e1", "type": "protein", "text": [ "HMGB1" ], "offsets": [ [ 84, 89 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P07156" }, { "db_name": "UniProt", "db_id": "P09429" }, { "db_name": "UniProt", "db_id": "P10103" }, { "db_name": "UniProt", "db_id": "P12682" }, { "db_name": "UniProt", "db_id": "P36194" }, { "db_name": "UniProt", "db_id": "Q4R844" }, { "db_name": "UniProt", "db_id": "Q6YKA4" } ] }, { "id": "DS.d838.s0.e2", "type": "compound", "text": [ "oxygen" ], "offsets": [ [ 108, 114 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "977" } ] }, { "id": "DS.d838.s0.e3", "type": "protein", "text": [ "cyclooxygenase-2" ], "offsets": [ [ 159, 175 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O02768" }, { "db_name": "UniProt", "db_id": "O19183" }, { "db_name": "UniProt", "db_id": "O62698" }, { "db_name": "UniProt", "db_id": "O62725" }, { "db_name": "UniProt", "db_id": "P27607" }, { "db_name": "UniProt", "db_id": "P35354" }, { "db_name": "UniProt", "db_id": "P35355" }, { "db_name": "UniProt", "db_id": "P70682" }, { "db_name": "UniProt", "db_id": "P79208" }, { "db_name": "UniProt", "db_id": "Q05769" } ] } ]
[]
[]
[ { "id": "DS.d838.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d838.s0.e2", "arg2_id": "DS.d838.s0.e0", "normalized": [] }, { "id": "DS.d838.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d838.s0.e2", "arg2_id": "DS.d838.s0.e1", "normalized": [] } ]
DS.d839
18715148
[ { "id": "DS.d839.s0", "type": "", "text": [ "NO, a gas, is produced from L-arginine by different isoforms of nitric oxide synthase (NOS) and serves many normal physiologic purposes, such as promoting vasodilation of blood vessels and mediating communication between nervous system cells." ], "offsets": [ [ 0, 242 ] ] } ]
[ { "id": "DS.d839.s0.e0", "type": "compound", "text": [ "arginine" ], "offsets": [ [ 30, 38 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "232" }, { "db_name": "PubChem", "db_id": "4367" }, { "db_name": "PubChem", "db_id": "6322" } ] }, { "id": "DS.d839.s0.e1", "type": "protein", "text": [ "nitric oxide synthase" ], "offsets": [ [ 64, 85 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O61309" }, { "db_name": "UniProt", "db_id": "O61608" }, { "db_name": "UniProt", "db_id": "Q27571" }, { "db_name": "UniProt", "db_id": "Q9I9M2" } ] }, { "id": "DS.d839.s0.e2", "type": "protein", "text": [ "NOS" ], "offsets": [ [ 87, 90 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O54705" }, { "db_name": "UniProt", "db_id": "O61309" }, { "db_name": "UniProt", "db_id": "O61608" }, { "db_name": "UniProt", "db_id": "Q26240" }, { "db_name": "UniProt", "db_id": "Q28969" }, { "db_name": "UniProt", "db_id": "Q9I9M2" } ] } ]
[]
[]
[ { "id": "DS.d839.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d839.s0.e0", "arg2_id": "DS.d839.s0.e1", "normalized": [] }, { "id": "DS.d839.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d839.s0.e0", "arg2_id": "DS.d839.s0.e2", "normalized": [] } ]
DS.d840
18715149
[ { "id": "DS.d840.s0", "type": "", "text": [ "As one of the very few repair systems for oxidized proteins, MsrA and MsrB enzymes play a major role in protein homeostasis during aging and have also been involved in cellular defenses against oxidative stress, by scavenging reactive oxygen species." ], "offsets": [ [ 0, 250 ] ] } ]
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DS.d841
18715284
[ { "id": "DS.d841.s0", "type": "", "text": [ "High density lipoprotein-cholesterol levels increase with age in American women but not in Hong Kong Chinese women." ], "offsets": [ [ 0, 115 ] ] }, { "id": "DS.d841.s1", "type": "", "text": [ "High-density lipoprotein (HDL) cholesterol is a powerful cardiovascular risk factor." ], "offsets": [ [ 116, 200 ] ] } ]
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DS.d842
18715643
[ { "id": "DS.d842.s0", "type": "", "text": [ "Repeated injections of arsenic trioxide induced oxidative stress and hepatotoxicity in mice as revealed from elevated levels of glutamate oxaloacetate transaminases, glutamate pyruvate transaminases, acid and alkaline phosphatases, lipid peroxidation along with reduction of superoxide dismutase, catalase, reduced glutathione content, glutathione reductase and succinate dehydrogenase activities." ], "offsets": [ [ 0, 397 ] ] }, { "id": "DS.d842.s1", "type": "", "text": [ "Hepatoprotective potential of vitamin C was indicated by its ability to restore GSH, SOD, CAT, AcP, AlkP and GRD levels towards near normal." ], "offsets": [ [ 398, 538 ] ] } ]
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"db_id": "P22782" }, { "db_name": "UniProt", "db_id": "P25309" }, { "db_name": "UniProt", "db_id": "P25819" }, { "db_name": "UniProt", "db_id": "P26825" }, { "db_name": "UniProt", "db_id": "P26826" }, { "db_name": "UniProt", "db_id": "P32796" }, { "db_name": "UniProt", "db_id": "P36882" }, { "db_name": "UniProt", "db_id": "P36883" }, { "db_name": "UniProt", "db_id": "P43155" }, { "db_name": "UniProt", "db_id": "P47934" }, { "db_name": "UniProt", "db_id": "P49417" }, { "db_name": "UniProt", "db_id": "P52826" }, { "db_name": "UniProt", "db_id": "P58777" }, { "db_name": "UniProt", "db_id": "P62577" }, { "db_name": "UniProt", "db_id": "P62578" }, { "db_name": "UniProt", "db_id": "P62579" }, { "db_name": "UniProt", "db_id": "P62580" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q00614" }, { "db_name": "UniProt", "db_id": "Q02736" }, { "db_name": "UniProt", "db_id": "Q03058" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q704S8" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PWF7" } ] }, { "id": "DS.d842.s1.e3", "type": "protein", "text": [ "AcP" ], "offsets": [ [ 493, 496 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P56544" } ] }, { "id": "DS.d842.s1.e4", "type": "protein", "text": [ "GRD" ], "offsets": [ [ 507, 510 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q24352" } ] } ]
[]
[]
[]
DS.d843
18715823
[ { "id": "DS.d843.s0", "type": "", "text": [ "The interaction of quercetin, which is a bioflavonoid, with bovine serum albumin (BSA) was investigated under pseudo-physiological conditions by the application of UV-vis spectrometry, spectrofluorimetry and cyclic voltammetry (CV)." ], "offsets": [ [ 0, 232 ] ] }, { "id": "DS.d843.s1", "type": "", "text": [ "1x10(-5) mol L(-1)), most of the site marker reacted with the quercetin-BSA, but free warfarin was present at higher concentrations." ], "offsets": [ [ 233, 365 ] ] } ]
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[]
[]
[ { "id": "DS.d843.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d843.s0.e1", "arg2_id": "DS.d843.s0.e2", "normalized": [] }, { "id": "DS.d843.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d843.s0.e0", "arg2_id": "DS.d843.s0.e2", "normalized": [] }, { "id": "DS.d843.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d843.s0.e1", "arg2_id": "DS.d843.s0.e3", "normalized": [] }, { "id": "DS.d843.s0.i3", "type": "compound-protein-interaction", "arg1_id": "DS.d843.s0.e0", "arg2_id": "DS.d843.s0.e3", "normalized": [] } ]
DS.d844
18715824
[ { "id": "DS.d844.s0", "type": "", "text": [ "Under optimum conditions, the fluorescence intensity of BSA-GNPs is linearly proportional to nickel concentration from 6.0x10(-8)mol/L to 8.0x10(-6)mol/L with a detection limit of 1.0x10(-8)mol/L." ], "offsets": [ [ 0, 196 ] ] } ]
[ { "id": "DS.d844.s0.e0", "type": "protein", "text": [ "BSA" ], "offsets": [ [ 56, 59 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02769" } ] }, { "id": "DS.d844.s0.e1", "type": "compound", "text": [ "nickel" ], "offsets": [ [ 93, 99 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "935" } ] } ]
[]
[]
[ { "id": "DS.d844.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d844.s0.e1", "arg2_id": "DS.d844.s0.e0", "normalized": [] } ]
DS.d845
18716315
[ { "id": "DS.d845.s0", "type": "", "text": [ "C18 and C20Gb(3) were, in mixtures without C24 :1Gb(3), dominant negative for gp120 vesicle binding." ], "offsets": [ [ 0, 100 ] ] }, { "id": "DS.d845.s1", "type": "", "text": [ "Gp120/VT1bound C18 and C24 :1Gb(3) mixtures, although neither isoform bound alone." ], "offsets": [ [ 101, 183 ] ] }, { "id": "DS.d845.s2", "type": "", "text": [ "Monolayer surface pressure measurement showed VT1, but not VT2, bound Gb(3) at cellular DRM surface pressures, and confirmed loss of VT1 and gp120 (but not VT2) specific C18Gb(3) binding." ], "offsets": [ [ 184, 371 ] ] } ]
[ { "id": "DS.d845.s0.e0", "type": "compound", "text": [ "C24" ], "offsets": [ [ 43, 46 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "446804" } ] }, { "id": "DS.d845.s0.e1", "type": "protein", "text": [ "gp120" ], "offsets": [ [ 78, 83 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12164" }, { "db_name": "UniProt", "db_id": "O41803" }, { "db_name": "UniProt", "db_id": "O70902" }, { "db_name": "UniProt", "db_id": "O89292" }, { "db_name": "UniProt", "db_id": "O91086" }, { "db_name": "UniProt", "db_id": "P03375" }, { "db_name": "UniProt", "db_id": "P03377" }, { "db_name": "UniProt", "db_id": "P03378" }, { "db_name": "UniProt", "db_id": "P04577" }, { "db_name": "UniProt", "db_id": "P04578" }, { "db_name": "UniProt", "db_id": "P04579" }, { "db_name": "UniProt", "db_id": "P04580" }, { "db_name": "UniProt", "db_id": "P04581" }, { "db_name": "UniProt", "db_id": "P04582" }, { "db_name": "UniProt", "db_id": "P04583" }, { "db_name": "UniProt", "db_id": "P04624" }, { "db_name": "UniProt", "db_id": "P05877" }, { "db_name": "UniProt", "db_id": "P05878" }, { "db_name": "UniProt", "db_id": "P05879" }, { "db_name": "UniProt", "db_id": "P05880" }, { "db_name": "UniProt", "db_id": "P05881" }, { "db_name": "UniProt", "db_id": "P05882" }, { "db_name": "UniProt", "db_id": "P05883" }, { "db_name": "UniProt", "db_id": "P05884" }, { "db_name": "UniProt", "db_id": "P05885" }, { "db_name": "UniProt", "db_id": "P05886" }, { "db_name": "UniProt", "db_id": "P08810" }, { "db_name": "UniProt", "db_id": "P11267" }, { "db_name": "UniProt", "db_id": "P12449" }, { "db_name": "UniProt", "db_id": "P12487" }, { "db_name": "UniProt", "db_id": "P12488" }, { "db_name": "UniProt", "db_id": "P12489" }, { "db_name": "UniProt", "db_id": "P12490" }, { "db_name": "UniProt", "db_id": "P12491" }, { "db_name": "UniProt", "db_id": "P12492" }, { "db_name": "UniProt", "db_id": "P15831" }, { "db_name": "UniProt", "db_id": "P17281" }, { "db_name": "UniProt", "db_id": "P17755" }, { "db_name": "UniProt", "db_id": "P18040" }, { "db_name": "UniProt", "db_id": "P18094" }, { "db_name": "UniProt", "db_id": "P18799" }, { "db_name": "UniProt", "db_id": "P19503" }, { "db_name": "UniProt", "db_id": "P19549" }, { "db_name": "UniProt", "db_id": "P19550" }, { "db_name": "UniProt", "db_id": "P19551" }, { "db_name": "UniProt", "db_id": "P20871" }, { "db_name": "UniProt", "db_id": "P20872" }, { "db_name": "UniProt", "db_id": "P20888" }, { "db_name": "UniProt", "db_id": "P22380" }, { "db_name": "UniProt", "db_id": "P24105" }, { "db_name": "UniProt", "db_id": "P27757" }, { "db_name": "UniProt", "db_id": "P27977" }, { "db_name": "UniProt", "db_id": "P31819" }, { "db_name": "UniProt", "db_id": "P31872" }, { "db_name": "UniProt", "db_id": "P32536" }, { "db_name": "UniProt", "db_id": "P35961" }, { "db_name": "UniProt", "db_id": "Q02837" }, { "db_name": "UniProt", "db_id": "Q1A243" }, { "db_name": "UniProt", "db_id": "Q1A261" }, { "db_name": "UniProt", "db_id": "Q70626" }, { "db_name": "UniProt", "db_id": "Q73372" }, { "db_name": "UniProt", "db_id": "Q74126" }, { "db_name": "UniProt", "db_id": "Q75008" }, { "db_name": "UniProt", "db_id": "Q76638" }, { "db_name": "UniProt", "db_id": "Q77377" }, { "db_name": "UniProt", "db_id": "Q79670" }, { "db_name": "UniProt", "db_id": "Q89607" }, { "db_name": "UniProt", "db_id": "Q8AIH5" }, { "db_name": "UniProt", "db_id": "Q9IDV2" }, { "db_name": "UniProt", "db_id": "Q9Q714" }, { "db_name": "UniProt", "db_id": "Q9QBY2" }, { "db_name": "UniProt", "db_id": "Q9QBZ0" }, { "db_name": "UniProt", "db_id": "Q9QBZ4" }, { "db_name": "UniProt", "db_id": "Q9QBZ8" }, { "db_name": "UniProt", "db_id": "Q9QSQ7" }, { "db_name": "UniProt", "db_id": "Q9WC60" }, { "db_name": "UniProt", "db_id": "Q9WC69" } ] }, { "id": "DS.d845.s1.e0", "type": "protein", "text": [ "Gp120" ], "offsets": [ [ 101, 106 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12164" }, { "db_name": "UniProt", "db_id": "O41803" }, { "db_name": "UniProt", "db_id": "O70902" }, { "db_name": "UniProt", "db_id": "O89292" }, { "db_name": "UniProt", "db_id": "O91086" }, { "db_name": "UniProt", "db_id": "P03375" }, { "db_name": "UniProt", "db_id": "P03377" }, { "db_name": "UniProt", "db_id": "P03378" }, { "db_name": "UniProt", "db_id": "P04577" }, { "db_name": "UniProt", "db_id": "P04578" }, { "db_name": "UniProt", "db_id": "P04579" }, { "db_name": "UniProt", "db_id": "P04580" }, { "db_name": "UniProt", "db_id": "P04581" }, { "db_name": "UniProt", "db_id": "P04582" }, { "db_name": "UniProt", "db_id": "P04583" }, { "db_name": "UniProt", "db_id": "P04624" }, { "db_name": "UniProt", "db_id": "P05877" }, { "db_name": "UniProt", "db_id": "P05878" }, { "db_name": "UniProt", "db_id": "P05879" }, { "db_name": "UniProt", "db_id": "P05880" }, { "db_name": "UniProt", "db_id": "P05881" }, { "db_name": "UniProt", "db_id": "P05882" }, { "db_name": "UniProt", "db_id": "P05883" }, { "db_name": "UniProt", "db_id": "P05884" }, { "db_name": "UniProt", "db_id": "P05885" }, { "db_name": "UniProt", "db_id": "P05886" }, { "db_name": "UniProt", "db_id": "P08810" }, { "db_name": "UniProt", "db_id": "P11267" }, { "db_name": "UniProt", "db_id": "P12449" }, { "db_name": "UniProt", "db_id": "P12487" }, { "db_name": "UniProt", "db_id": "P12488" }, { "db_name": "UniProt", "db_id": "P12489" }, { "db_name": "UniProt", "db_id": "P12490" }, { "db_name": "UniProt", "db_id": "P12491" }, { "db_name": "UniProt", "db_id": "P12492" }, { "db_name": "UniProt", "db_id": "P15831" }, { "db_name": "UniProt", "db_id": "P17281" }, { "db_name": "UniProt", "db_id": "P17755" }, { "db_name": "UniProt", "db_id": "P18040" }, { "db_name": "UniProt", "db_id": "P18094" }, { "db_name": "UniProt", "db_id": "P18799" }, { "db_name": "UniProt", "db_id": "P19503" }, { "db_name": "UniProt", "db_id": "P19549" }, { "db_name": "UniProt", "db_id": "P19550" }, { "db_name": "UniProt", "db_id": "P19551" }, { "db_name": "UniProt", "db_id": "P20871" }, { "db_name": "UniProt", "db_id": "P20872" }, { "db_name": "UniProt", "db_id": "P20888" }, { "db_name": "UniProt", "db_id": "P22380" }, { "db_name": "UniProt", "db_id": "P24105" }, { "db_name": "UniProt", "db_id": "P27757" }, { "db_name": "UniProt", "db_id": "P27977" }, { "db_name": "UniProt", "db_id": "P31819" }, { "db_name": "UniProt", "db_id": "P31872" }, { "db_name": "UniProt", "db_id": "P32536" }, { "db_name": "UniProt", "db_id": "P35961" }, { "db_name": "UniProt", "db_id": "Q02837" }, { "db_name": "UniProt", "db_id": "Q1A243" }, { "db_name": "UniProt", "db_id": "Q1A261" }, { "db_name": "UniProt", "db_id": "Q70626" }, { "db_name": "UniProt", "db_id": "Q73372" }, { "db_name": "UniProt", "db_id": "Q74126" }, { "db_name": "UniProt", "db_id": "Q75008" }, { "db_name": "UniProt", "db_id": "Q76638" }, { "db_name": "UniProt", "db_id": "Q77377" }, { "db_name": "UniProt", "db_id": "Q79670" }, { "db_name": "UniProt", "db_id": "Q89607" }, { "db_name": "UniProt", "db_id": "Q8AIH5" }, { "db_name": "UniProt", "db_id": "Q9IDV2" }, { "db_name": "UniProt", "db_id": "Q9Q714" }, { "db_name": "UniProt", "db_id": "Q9QBY2" }, { "db_name": "UniProt", "db_id": "Q9QBZ0" }, { "db_name": "UniProt", "db_id": "Q9QBZ4" }, { "db_name": "UniProt", "db_id": "Q9QBZ8" }, { "db_name": "UniProt", "db_id": "Q9QSQ7" }, { "db_name": "UniProt", "db_id": "Q9WC60" }, { "db_name": "UniProt", "db_id": "Q9WC69" } ] }, { "id": "DS.d845.s1.e1", "type": "compound", "text": [ "C24" ], "offsets": [ [ 124, 127 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "446804" } ] }, { "id": "DS.d845.s2.e0", "type": "compound", "text": [ "Gb(3" ], "offsets": [ [ 254, 258 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5353448" } ] }, { "id": "DS.d845.s2.e1", "type": "protein", "text": [ "gp120" ], "offsets": [ [ 325, 330 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12164" }, { "db_name": "UniProt", "db_id": "O41803" }, { "db_name": "UniProt", "db_id": "O70902" }, { "db_name": "UniProt", "db_id": "O89292" }, { "db_name": "UniProt", "db_id": "O91086" }, { "db_name": "UniProt", "db_id": "P03375" }, { "db_name": "UniProt", "db_id": "P03377" }, { "db_name": "UniProt", "db_id": "P03378" }, { "db_name": "UniProt", "db_id": "P04577" }, { "db_name": "UniProt", "db_id": "P04578" }, { "db_name": "UniProt", "db_id": "P04579" }, { "db_name": "UniProt", "db_id": "P04580" }, { "db_name": "UniProt", "db_id": "P04581" }, { "db_name": "UniProt", "db_id": "P04582" }, { "db_name": "UniProt", "db_id": "P04583" }, { "db_name": "UniProt", "db_id": "P04624" }, { "db_name": "UniProt", "db_id": "P05877" }, { "db_name": "UniProt", "db_id": "P05878" }, { "db_name": "UniProt", "db_id": "P05879" }, { "db_name": "UniProt", "db_id": "P05880" }, { "db_name": "UniProt", "db_id": "P05881" }, { "db_name": "UniProt", "db_id": "P05882" }, { "db_name": "UniProt", "db_id": "P05883" }, { "db_name": "UniProt", "db_id": "P05884" }, { "db_name": "UniProt", "db_id": "P05885" }, { "db_name": "UniProt", "db_id": "P05886" }, { "db_name": "UniProt", "db_id": "P08810" }, { "db_name": "UniProt", "db_id": "P11267" }, { "db_name": "UniProt", "db_id": "P12449" }, { "db_name": "UniProt", "db_id": "P12487" }, { "db_name": "UniProt", "db_id": "P12488" }, { "db_name": "UniProt", "db_id": "P12489" }, { "db_name": "UniProt", "db_id": "P12490" }, { "db_name": "UniProt", "db_id": "P12491" }, { "db_name": "UniProt", "db_id": "P12492" }, { "db_name": "UniProt", "db_id": "P15831" }, { "db_name": "UniProt", "db_id": "P17281" }, { "db_name": "UniProt", "db_id": "P17755" }, { "db_name": "UniProt", "db_id": "P18040" }, { "db_name": "UniProt", "db_id": "P18094" }, { "db_name": "UniProt", "db_id": "P18799" }, { "db_name": "UniProt", "db_id": "P19503" }, { "db_name": "UniProt", "db_id": "P19549" }, { "db_name": "UniProt", "db_id": "P19550" }, { "db_name": "UniProt", "db_id": "P19551" }, { "db_name": "UniProt", "db_id": "P20871" }, { "db_name": "UniProt", "db_id": "P20872" }, { "db_name": "UniProt", "db_id": "P20888" }, { "db_name": "UniProt", "db_id": "P22380" }, { "db_name": "UniProt", "db_id": "P24105" }, { "db_name": "UniProt", "db_id": "P27757" }, { "db_name": "UniProt", "db_id": "P27977" }, { "db_name": "UniProt", "db_id": "P31819" }, { "db_name": "UniProt", "db_id": "P31872" }, { "db_name": "UniProt", "db_id": "P32536" }, { "db_name": "UniProt", "db_id": "P35961" }, { "db_name": "UniProt", "db_id": "Q02837" }, { "db_name": "UniProt", "db_id": "Q1A243" }, { "db_name": "UniProt", "db_id": "Q1A261" }, { "db_name": "UniProt", "db_id": "Q70626" }, { "db_name": "UniProt", "db_id": "Q73372" }, { "db_name": "UniProt", "db_id": "Q74126" }, { "db_name": "UniProt", "db_id": "Q75008" }, { "db_name": "UniProt", "db_id": "Q76638" }, { "db_name": "UniProt", "db_id": "Q77377" }, { "db_name": "UniProt", "db_id": "Q79670" }, { "db_name": "UniProt", "db_id": "Q89607" }, { "db_name": "UniProt", "db_id": "Q8AIH5" }, { "db_name": "UniProt", "db_id": "Q9IDV2" }, { "db_name": "UniProt", "db_id": "Q9Q714" }, { "db_name": "UniProt", "db_id": "Q9QBY2" }, { "db_name": "UniProt", "db_id": "Q9QBZ0" }, { "db_name": "UniProt", "db_id": "Q9QBZ4" }, { "db_name": "UniProt", "db_id": "Q9QBZ8" }, { "db_name": "UniProt", "db_id": "Q9QSQ7" }, { "db_name": "UniProt", "db_id": "Q9WC60" }, { "db_name": "UniProt", "db_id": "Q9WC69" } ] } ]
[]
[]
[ { "id": "DS.d845.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d845.s1.e1", "arg2_id": "DS.d845.s1.e0", "normalized": [] } ]
DS.d846
18716607
[ { "id": "DS.d846.s0", "type": "", "text": [ "Cholinesterase inhibition in chlorpyrifos workers: Characterization of biomarkers of exposure and response in relation to urinary TCPy." ], "offsets": [ [ 0, 135 ] ] }, { "id": "DS.d846.s1", "type": "", "text": [ "The objective of this study was to evaluate the quantitative relation between measured red blood cell acetylcholinesterase (RBC AChE) and plasma butyrylcholinesterase (BuChE) activities with exposure to chlorpyrifos (CPF) as assessed by measurement of urinary 3,5,6-trichloro-2-pyridinol (TCPy) in a study group of workers occupationally exposed in the manufacture of CPF and a referent group of chemical manufacturing workers." ], "offsets": [ [ 136, 563 ] ] } ]
[ { "id": "DS.d846.s0.e0", "type": "protein", "text": [ "Cholinesterase" ], "offsets": [ [ 0, 14 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P32749" }, { "db_name": "UniProt", "db_id": "P32750" }, { "db_name": "UniProt", "db_id": "P32751" }, { "db_name": "UniProt", "db_id": "P32752" }, { "db_name": "UniProt", "db_id": "P32753" }, { "db_name": "UniProt", "db_id": "P81908" } ] }, { "id": "DS.d846.s0.e1", "type": "compound", "text": [ "TCPy" ], "offsets": [ [ 130, 134 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "62764" } ] }, { "id": "DS.d846.s1.e0", "type": "protein", "text": [ "acetylcholinesterase" ], "offsets": [ [ 238, 258 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q867X2" }, { "db_name": "UniProt", "db_id": "Q867X3" }, { "db_name": "UniProt", "db_id": "Q86GC9" }, { "db_name": "UniProt", "db_id": "Q92081" } ] }, { "id": "DS.d846.s1.e1", "type": "compound", "text": [ "chlorpyrifos" ], "offsets": [ [ 339, 351 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2730" } ] }, { "id": "DS.d846.s1.e2", "type": "compound", "text": [ "3,5,6-trichloro-2-pyridinol" ], "offsets": [ [ 396, 423 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "23017" } ] }, { "id": "DS.d846.s1.e3", "type": "compound", "text": [ "TCPy" ], "offsets": [ [ 425, 429 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "62764" } ] } ]
[]
[]
[ { "id": "DS.d846.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d846.s1.e1", "arg2_id": "DS.d846.s1.e0", "normalized": [] }, { "id": "DS.d846.s1.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d846.s1.e3", "arg2_id": "DS.d846.s1.e0", "normalized": [] }, { "id": "DS.d846.s1.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d846.s1.e2", "arg2_id": "DS.d846.s1.e0", "normalized": [] } ]
DS.d847
18716756
[ { "id": "DS.d847.s0", "type": "", "text": [ "Immunofluorescence analysis revealed that two known virulence-associated surface proteins featuring Leu-Pro-X-Thr-Gly motif, muramidase-released protein and surface antigen one, were absent in the DeltasrtA." ], "offsets": [ [ 0, 207 ] ] } ]
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"db_name": "UniProt", "db_id": "Q9WC60" }, { "db_name": "UniProt", "db_id": "Q9WC69" } ] }, { "id": "DS.d847.s0.e1", "type": "compound", "text": [ "Leu-Pro" ], "offsets": [ [ 100, 107 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "3977067" } ] }, { "id": "DS.d847.s0.e2", "type": "compound", "text": [ "Gly" ], "offsets": [ [ 114, 117 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "750" }, { "db_name": "PubChem", "db_id": "5460845" } ] }, { "id": "DS.d847.s0.e3", "type": "protein", "text": [ "muramidase" ], "offsets": [ [ 125, 135 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O64362" }, { "db_name": "UniProt", "db_id": "O80288" }, { "db_name": "UniProt", "db_id": "O80292" }, { "db_name": "UniProt", "db_id": "P00720" }, { "db_name": "UniProt", "db_id": "P03706" }, { "db_name": "UniProt", "db_id": "P07540" }, { "db_name": "UniProt", "db_id": "P09963" }, { "db_name": "UniProt", "db_id": "P10439" }, { "db_name": "UniProt", "db_id": "P11187" }, { "db_name": "UniProt", "db_id": "P15057" }, { "db_name": "UniProt", "db_id": "P19385" }, { "db_name": "UniProt", "db_id": "P19386" }, { "db_name": "UniProt", "db_id": "P27359" }, { "db_name": "UniProt", "db_id": "P33486" }, { "db_name": "UniProt", "db_id": "P51728" }, { "db_name": "UniProt", "db_id": "P51771" }, { "db_name": "UniProt", "db_id": "P62692" }, { "db_name": "UniProt", "db_id": "P62693" }, { "db_name": "UniProt", "db_id": "P68920" }, { "db_name": "UniProt", "db_id": "P68921" }, { "db_name": "UniProt", "db_id": "P76159" }, { "db_name": "UniProt", "db_id": "P78285" }, { "db_name": "UniProt", "db_id": "Q37875" }, { "db_name": "UniProt", "db_id": "Q37896" }, { "db_name": "UniProt", "db_id": "Q9T1T5" }, { "db_name": "UniProt", "db_id": "Q9T1X2" }, { "db_name": "UniProt", "db_id": "Q9ZXB7" } ] } ]
[]
[]
[ { "id": "DS.d847.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d847.s0.e1", "arg2_id": "DS.d847.s0.e0", "normalized": [] }, { "id": "DS.d847.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d847.s0.e2", "arg2_id": "DS.d847.s0.e0", "normalized": [] } ]
DS.d848
18716761
[ { "id": "DS.d848.s0", "type": "", "text": [ "In addition, neuronal nitric oxide synthase, another component of the NMDA/nitric oxide/cGMP intracellular pathway, has been reported to be dysregulated in schizophrenia patients." ], "offsets": [ [ 0, 179 ] ] } ]
[ { "id": "DS.d848.s0.e0", "type": "protein", "text": [ "nitric oxide synthase" ], "offsets": [ [ 22, 43 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O61309" }, { "db_name": "UniProt", "db_id": "O61608" }, { "db_name": "UniProt", "db_id": "Q27571" }, { "db_name": "UniProt", "db_id": "Q9I9M2" } ] }, { "id": "DS.d848.s0.e2", "type": "compound", "text": [ "nitric oxide" ], "offsets": [ [ 75, 87 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "145068" } ] }, { "id": "DS.d848.s0.e3", "type": "compound", "text": [ "cGMP" ], "offsets": [ [ 88, 92 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "24316" } ] } ]
[]
[]
[ { "id": "DS.d848.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d848.s0.e2", "arg2_id": "DS.d848.s0.e0", "normalized": [] }, { "id": "DS.d848.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d848.s0.e3", "arg2_id": "DS.d848.s0.e0", "normalized": [] } ]
DS.d850
18716782
[ { "id": "DS.d850.s0", "type": "", "text": [ "A role for natriuretic peptide in lipopolysaccharide-induced fever in Pekin ducks (Anas platyrhynchos): is natriuretic peptide an endogenous antipyretic in birds." ], "offsets": [ [ 0, 162 ] ] }, { "id": "DS.d850.s1", "type": "", "text": [ "We induced fever in Pekin ducks with lipopolysaccharide and, at the same time, treated the animals with natriuretic peptide antiserum at a dose that effectively inhibited the known renal actions of endogenously secreted natriuretic peptide." ], "offsets": [ [ 163, 403 ] ] } ]
[ { "id": "DS.d850.s0.e0", "type": "protein", "text": [ "natriuretic peptide" ], "offsets": [ [ 11, 30 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P28374" } ] }, { "id": "DS.d850.s0.e1", "type": "compound", "text": [ "lipopolysaccharide" ], "offsets": [ [ 34, 52 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "11970143" } ] }, { "id": "DS.d850.s0.e2", "type": "protein", "text": [ "natriuretic peptide" ], "offsets": [ [ 107, 126 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P28374" } ] }, { "id": "DS.d850.s1.e0", "type": "compound", "text": [ "lipopolysaccharide" ], "offsets": [ [ 200, 218 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "11970143" } ] }, { "id": "DS.d850.s1.e1", "type": "protein", "text": [ "natriuretic peptide" ], "offsets": [ [ 267, 286 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P28374" } ] }, { "id": "DS.d850.s1.e2", "type": "protein", "text": [ "natriuretic peptide" ], "offsets": [ [ 383, 402 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P28374" } ] } ]
[]
[]
[]
DS.d851
18716808
[ { "id": "DS.d851.s0", "type": "", "text": [ "Among the Gram-negative bacteria, 100% of the Escherichia coli isolates (including extended spectrum beta-lactamase (ESBL)-producers) were tigecycline-susceptible, while about 10% of the Enterobacter cloacae and Klebsiella pneumoniae isolates were resistant." ], "offsets": [ [ 0, 258 ] ] } ]
[ { "id": "DS.d851.s0.e0", "type": "protein", "text": [ "beta-lactamase" ], "offsets": [ [ 101, 115 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P80298" }, { "db_name": "UniProt", "db_id": "P80545" }, { "db_name": "UniProt", "db_id": "P81173" } ] }, { "id": "DS.d851.s0.e1", "type": "compound", "text": [ "tigecycline" ], "offsets": [ [ 139, 150 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "54686904" } ] } ]
[]
[]
[ { "id": "DS.d851.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d851.s0.e1", "arg2_id": "DS.d851.s0.e0", "normalized": [] } ]
DS.d853
18716864
[ { "id": "DS.d853.s0", "type": "", "text": [ "The data presented here show that NH4Cl (5 mM) mediates astroglial cell swelling, and that treatment with NH4Cl or lactate (25 mM) causes rearrangements of actin filaments and reduces astroglial glutamate uptake capacity." ], "offsets": [ [ 0, 221 ] ] } ]
[ { "id": "DS.d853.s0.e0", "type": "compound", "text": [ "lactate" ], "offsets": [ [ 115, 122 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "612" } ] }, { "id": "DS.d853.s0.e1", "type": "protein", "text": [ "actin" ], "offsets": [ [ 156, 161 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O00937" }, { "db_name": "UniProt", "db_id": "O13419" }, { "db_name": "UniProt", "db_id": "O16808" }, { "db_name": "UniProt", "db_id": "O17320" }, { "db_name": "UniProt", "db_id": "O65314" }, { "db_name": "UniProt", "db_id": "O65315" }, { "db_name": "UniProt", "db_id": "O65316" }, { "db_name": "UniProt", "db_id": "O74258" }, { "db_name": "UniProt", "db_id": "O81221" }, { "db_name": "UniProt", "db_id": "P02577" }, { "db_name": "UniProt", "db_id": "P10365" }, { "db_name": "UniProt", "db_id": "P10989" }, { "db_name": "UniProt", "db_id": "P11426" }, { "db_name": "UniProt", "db_id": "P13363" }, { "db_name": "UniProt", "db_id": "P14235" }, { "db_name": "UniProt", "db_id": "P17128" }, { "db_name": "UniProt", "db_id": "P20904" }, { "db_name": "UniProt", "db_id": "P24902" }, { "db_name": "UniProt", "db_id": "P26182" }, { "db_name": "UniProt", "db_id": "P26183" }, { "db_name": "UniProt", "db_id": "P30161" }, { "db_name": "UniProt", "db_id": "P45520" }, { "db_name": "UniProt", "db_id": "P45521" }, { "db_name": "UniProt", "db_id": "P48465" }, { "db_name": "UniProt", "db_id": "P50138" }, { "db_name": "UniProt", "db_id": "P51775" }, { "db_name": "UniProt", "db_id": "P53455" }, { "db_name": "UniProt", "db_id": "P53476" }, { "db_name": "UniProt", "db_id": "P53477" }, { "db_name": "UniProt", "db_id": "P53491" }, { "db_name": "UniProt", "db_id": "P53498" }, { "db_name": "UniProt", "db_id": "P53499" }, { "db_name": "UniProt", "db_id": "P53500" }, { "db_name": "UniProt", "db_id": "P53502" }, { "db_name": "UniProt", "db_id": "P53689" }, { "db_name": "UniProt", "db_id": "P60009" }, { "db_name": "UniProt", "db_id": "P60010" }, { "db_name": "UniProt", "db_id": "P60011" }, { "db_name": "UniProt", "db_id": "P68555" }, { "db_name": "UniProt", "db_id": "P78711" }, { "db_name": "UniProt", "db_id": "P80709" }, { "db_name": "UniProt", "db_id": "P81085" }, { "db_name": "UniProt", "db_id": "P90689" }, { "db_name": "UniProt", "db_id": "P91754" }, { "db_name": "UniProt", "db_id": "Q05214" }, { "db_name": "UniProt", "db_id": "Q11212" }, { "db_name": "UniProt", "db_id": "Q24733" }, { "db_name": "UniProt", "db_id": "Q2U7A3" }, { "db_name": "UniProt", "db_id": "Q39596" }, { "db_name": "UniProt", "db_id": "Q39758" }, { "db_name": "UniProt", "db_id": "Q6TCF2" }, { "db_name": "UniProt", "db_id": "Q75D00" }, { "db_name": "UniProt", "db_id": "Q8SWN8" }, { "db_name": "UniProt", "db_id": "Q8X119" }, { "db_name": "UniProt", "db_id": "Q92192" }, { "db_name": "UniProt", "db_id": "Q92193" }, { "db_name": "UniProt", "db_id": "Q99023" }, { "db_name": "UniProt", "db_id": "Q9P4D1" }, { "db_name": "UniProt", "db_id": "Q9UVF3" }, { "db_name": "UniProt", "db_id": "Q9UVX4" }, { "db_name": "UniProt", "db_id": "Q9UVZ8" } ] } ]
[]
[]
[ { "id": "DS.d853.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d853.s0.e0", "arg2_id": "DS.d853.s0.e1", "normalized": [] } ]
DS.d854
18716881
[ { "id": "DS.d854.s1", "type": "", "text": [ "Here, we proposed that Lap4, a vacuolar amino peptidase, is involved in glutathione catabolism under cadmium stress." ], "offsets": [ [ 0, 116 ] ] }, { "id": "DS.d854.s3", "type": "", "text": [ "Thus, under cadmium stress, Lap4 and gamma-glutamyl transferase seem to work together to assure an efficient glutathione turnover stored in the vacuole." ], "offsets": [ [ 117, 269 ] ] } ]
[ { "id": "DS.d854.s1.e0", "type": "protein", "text": [ "Lap4" ], "offsets": [ [ 23, 27 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q80U72" } ] }, { "id": "DS.d854.s1.e1", "type": "compound", "text": [ "cadmium" ], "offsets": [ [ 101, 108 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "23973" } ] }, { "id": "DS.d854.s3.e0", "type": "compound", "text": [ "cadmium" ], "offsets": [ [ 129, 136 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "23973" } ] }, { "id": "DS.d854.s3.e1", "type": "protein", "text": [ "Lap4" ], "offsets": [ [ 145, 149 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q80U72" } ] }, { "id": "DS.d854.s3.e2", "type": "compound", "text": [ "glutathione" ], "offsets": [ [ 226, 237 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "124886" } ] } ]
[]
[]
[ { "id": "DS.d854.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d854.s1.e1", "arg2_id": "DS.d854.s1.e0", "normalized": [] }, { "id": "DS.d854.s3.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d854.s3.e2", "arg2_id": "DS.d854.s3.e1", "normalized": [] }, { "id": "DS.d854.s3.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d854.s3.e0", "arg2_id": "DS.d854.s3.e1", "normalized": [] } ]
DS.d855
18716920
[ { "id": "DS.d855.s0", "type": "", "text": [ "In this research, the effects of pH, temperature, and oxygen on growth kinetics of a newly isolated strain of Bacillus circulans from the Amazon and their correlations with transglutaminase (TGase) production and cell sporulation were investigated." ], "offsets": [ [ 0, 248 ] ] } ]
[ { "id": "DS.d855.s0.e0", "type": "compound", "text": [ "oxygen" ], "offsets": [ [ 54, 60 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "977" } ] }, { "id": "DS.d855.s0.e1", "type": "protein", "text": [ "transglutaminase" ], "offsets": [ [ 173, 189 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P40746" }, { "db_name": "UniProt", "db_id": "P52183" }, { "db_name": "UniProt", "db_id": "P81453" }, { "db_name": "UniProt", "db_id": "Q819L3" }, { "db_name": "UniProt", "db_id": "Q81MS1" }, { "db_name": "UniProt", "db_id": "Q8GR90" }, { "db_name": "UniProt", "db_id": "Q9K5W7" } ] }, { "id": "DS.d855.s0.e2", "type": "protein", "text": [ "TGase" ], "offsets": [ [ 191, 196 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P40746" }, { "db_name": "UniProt", "db_id": "P81453" }, { "db_name": "UniProt", "db_id": "Q05187" }, { "db_name": "UniProt", "db_id": "Q819L3" }, { "db_name": "UniProt", "db_id": "Q81MS1" }, { "db_name": "UniProt", "db_id": "Q8GR90" }, { "db_name": "UniProt", "db_id": "Q9K5W7" } ] } ]
[]
[]
[ { "id": "DS.d855.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d855.s0.e0", "arg2_id": "DS.d855.s0.e1", "normalized": [] }, { "id": "DS.d855.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d855.s0.e0", "arg2_id": "DS.d855.s0.e2", "normalized": [] } ]
DS.d856
18717617
[ { "id": "DS.d856.s0", "type": "", "text": [ "No relationships were observed among mercury, selenium, and several other neurochemical biomarkers (dopamine-2, gamma-aminobutyric acid type A, muscarinic cholinergic, and nicotinic cholinergic receptors; cholinesterase and monoamine oxidase enzymes)." ], "offsets": [ [ 0, 251 ] ] } ]
[ { "id": "DS.d856.s0.e0", "type": "compound", "text": [ "mercury" ], "offsets": [ [ 37, 44 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "23931" } ] }, { "id": "DS.d856.s0.e1", "type": "compound", "text": [ "selenium" ], "offsets": [ [ 46, 54 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6326970" } ] }, { "id": "DS.d856.s0.e2", "type": "compound", "text": [ "dopamine" ], "offsets": [ [ 100, 108 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "681" } ] }, { "id": "DS.d856.s0.e3", "type": "compound", "text": [ "gamma-aminobutyric acid" ], "offsets": [ [ 112, 135 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "119" } ] }, { "id": "DS.d856.s0.e4", "type": "protein", "text": [ "cholinesterase" ], "offsets": [ [ 205, 219 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P32749" }, { "db_name": "UniProt", "db_id": "P32750" }, { "db_name": "UniProt", "db_id": "P32751" }, { "db_name": "UniProt", "db_id": "P32752" }, { "db_name": "UniProt", "db_id": "P32753" }, { "db_name": "UniProt", "db_id": "P81908" } ] }, { "id": "DS.d856.s0.e5", "type": "protein", "text": [ "monoamine oxidase" ], "offsets": [ [ 224, 241 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P49253" } ] } ]
[]
[]
[]
DS.d857
18717625
[ { "id": "DS.d857.s0", "type": "", "text": [ "Despite responsive antioxidative defense (increased activities of superoxide dismutase, ascorbate peroxidase, and pyrogallol peroxidase), Tl+ caused oxidative damage to lipids and proteins as evaluated by malondialdehyde and carbonyl group levels, and induced DNA strand breaks." ], "offsets": [ [ 0, 278 ] ] } ]
[ { "id": "DS.d857.s0.e0", "type": "protein", "text": [ "superoxide dismutase" ], "offsets": [ [ 66, 86 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O50258" } ] }, { "id": "DS.d857.s0.e1", "type": "protein", "text": [ "peroxidase" ], "offsets": [ [ 98, 108 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P15984" }, { "db_name": "UniProt", "db_id": "P16147" }, { "db_name": "UniProt", "db_id": "P84714" } ] }, { "id": "DS.d857.s0.e2", "type": "protein", "text": [ "peroxidase" ], "offsets": [ [ 125, 135 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P15984" }, { "db_name": "UniProt", "db_id": "P16147" }, { "db_name": "UniProt", "db_id": "P84714" } ] }, { "id": "DS.d857.s0.e3", "type": "compound", "text": [ "Tl" ], "offsets": [ [ 138, 140 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "105005" } ] } ]
[]
[]
[]
DS.d858
18717627
[ { "id": "DS.d858.s0", "type": "", "text": [ "However, Ref-1 inhibition followed by H2O2 treatment extensively induced the level of intracellular reactive oxygen species (ROS) through activation of the components of NADPH oxidase, like p22 (phox), p47 (phox), and Nox4." ], "offsets": [ [ 0, 223 ] ] } ]
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[]
[]
[ { "id": "DS.d858.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d858.s0.e0", "arg2_id": "DS.d858.s0.e2", "normalized": [] }, { "id": "DS.d858.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d858.s0.e0", "arg2_id": "DS.d858.s0.e1", "normalized": [] }, { "id": "DS.d858.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d858.s0.e0", "arg2_id": "DS.d858.s0.e3", "normalized": [] } ]
DS.d859
18717628
[ { "id": "DS.d859.s0", "type": "", "text": [ "We conclude that mitochondrial dysfunction can induce alpha-synuclein oligomerization via ATP depletion-driven microtubule depolymerization and via ROS increase-driven protein oxidation." ], "offsets": [ [ 0, 186 ] ] } ]
[ { "id": "DS.d859.s0.e0", "type": "protein", "text": [ "alpha-synuclein" ], "offsets": [ [ 54, 69 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O55042" }, { "db_name": "UniProt", "db_id": "P37377" }, { "db_name": "UniProt", "db_id": "P37840" }, { "db_name": "UniProt", "db_id": "P61138" }, { "db_name": "UniProt", "db_id": "P61139" }, { "db_name": "UniProt", "db_id": "P61140" }, { "db_name": "UniProt", "db_id": "P61141" }, { "db_name": "UniProt", "db_id": "P61142" }, { "db_name": "UniProt", "db_id": "P61143" }, { "db_name": "UniProt", "db_id": "P61144" }, { "db_name": "UniProt", "db_id": "P61145" }, { "db_name": "UniProt", "db_id": "P61146" }, { "db_name": "UniProt", "db_id": "P61147" }, { "db_name": "UniProt", "db_id": "Q3I5G7" }, { "db_name": "UniProt", "db_id": "Q3T0G8" }, { "db_name": "UniProt", "db_id": "Q91448" } ] }, { "id": "DS.d859.s0.e1", "type": "compound", "text": [ "ATP" ], "offsets": [ [ 90, 93 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5957" } ] } ]
[]
[]
[ { "id": "DS.d859.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d859.s0.e1", "arg2_id": "DS.d859.s0.e0", "normalized": [] } ]
DS.d860
18717715
[ { "id": "DS.d860.s0", "type": "", "text": [ "Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy." ], "offsets": [ [ 0, 133 ] ] }, { "id": "DS.d860.s1", "type": "", "text": [ "We previously showed that gene expression of synaptic vesicle protein 2A (SV2A), the binding site for the antiepileptic drug levetiracetam, is reduced during epileptogenesis in the rat." ], "offsets": [ [ 134, 319 ] ] } ]
[ { "id": "DS.d860.s0.e0", "type": "protein", "text": [ "synaptic vesicle protein 2A" ], "offsets": [ [ 24, 51 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q02563" }, { "db_name": "UniProt", "db_id": "Q9JIS5" } ] }, { "id": "DS.d860.s0.e1", "type": "compound", "text": [ "levetiracetam" ], "offsets": [ [ 74, 87 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5284583" } ] }, { "id": "DS.d860.s1.e0", "type": "protein", "text": [ "synaptic vesicle protein 2A" ], "offsets": [ [ 179, 206 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q02563" }, { "db_name": "UniProt", "db_id": "Q9JIS5" } ] }, { "id": "DS.d860.s1.e1", "type": "protein", "text": [ "SV2A" ], "offsets": [ [ 208, 212 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q29397" }, { "db_name": "UniProt", "db_id": "Q4R4X3" }, { "db_name": "UniProt", "db_id": "Q5R4L9" }, { "db_name": "UniProt", "db_id": "Q7L0J3" } ] }, { "id": "DS.d860.s1.e2", "type": "compound", "text": [ "levetiracetam" ], "offsets": [ [ 259, 272 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5284583" } ] } ]
[]
[]
[ { "id": "DS.d860.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d860.s0.e1", "arg2_id": "DS.d860.s0.e0", "normalized": [] }, { "id": "DS.d860.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d860.s1.e2", "arg2_id": "DS.d860.s1.e0", "normalized": [] }, { "id": "DS.d860.s1.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d860.s1.e2", "arg2_id": "DS.d860.s1.e1", "normalized": [] } ]
DS.d862
18718549
[ { "id": "DS.d862.s0", "type": "", "text": [ "We also demonstrated that the deletion of the ptsG gene doubled ATP-driven glutathione synthesis and increased cellular ATP synthetic activity." ], "offsets": [ [ 0, 143 ] ] } ]
[ { "id": "DS.d862.s0.e0", "type": "protein", "text": [ "ptsG" ], "offsets": [ [ 46, 50 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P20166" }, { "db_name": "UniProt", "db_id": "P37439" }, { "db_name": "UniProt", "db_id": "P42015" }, { "db_name": "UniProt", "db_id": "P47315" }, { "db_name": "UniProt", "db_id": "P57437" }, { "db_name": "UniProt", "db_id": "P69786" }, { "db_name": "UniProt", "db_id": "P69787" }, { "db_name": "UniProt", "db_id": "P69788" }, { "db_name": "UniProt", "db_id": "P75569" }, { "db_name": "UniProt", "db_id": "Q45298" }, { "db_name": "UniProt", "db_id": "Q46072" }, { "db_name": "UniProt", "db_id": "Q89AG6" }, { "db_name": "UniProt", "db_id": "Q8K9J0" } ] }, { "id": "DS.d862.s0.e1", "type": "compound", "text": [ "glutathione" ], "offsets": [ [ 75, 86 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "124886" } ] } ]
[]
[]
[ { "id": "DS.d862.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d862.s0.e1", "arg2_id": "DS.d862.s0.e0", "normalized": [] } ]
DS.d863
18718551
[ { "id": "DS.d863.s0", "type": "", "text": [ "Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation." ], "offsets": [ [ 0, 169 ] ] }, { "id": "DS.d863.s1", "type": "", "text": [ "In the present study, we showed that selenocystine (SeC), a naturally occurring selenoamino acid, induced caspase-independent apoptosis in MCF-7 breast carcinoma cells, which was accompanied by poly(ADP-ribose) polymerase (PARP) cleavage, caspase activation, DNA fragmentation, phosphatidylserine exposure and nuclear condensation." ], "offsets": [ [ 170, 501 ] ] }, { "id": "DS.d863.s2", "type": "", "text": [ "Silencing and attenuating of p53 activation with RNA interference and pifithrin-alpha treatment, respectively, partially suppressed SeC-induced cell apoptosis." ], "offsets": [ [ 502, 661 ] ] } ]
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[]
[]
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DS.d864
18718660
[ { "id": "DS.d864.s0", "type": "", "text": [ "Activation of c-Jun N-terminal kinase is essential for oxidative stress-induced Jurkat cell apoptosis by monochloramine." ], "offsets": [ [ 0, 120 ] ] }, { "id": "DS.d864.s1", "type": "", "text": [ "Within 10min of NH(2) Cl treatment, c-Jun N-terminal kinase (JNK) activation and elevation of cytosolic Ca(2+) were observed." ], "offsets": [ [ 121, 246 ] ] } ]
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[]
[]
[ { "id": "DS.d864.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d864.s0.e1", "arg2_id": "DS.d864.s0.e0", "normalized": [] } ]
DS.d865
18718713
[ { "id": "DS.d865.s0", "type": "", "text": [ "Induction in the activity of lignin peroxidase and azoreductase was observed during decolorization of Reactive Red 2 in the batch culture, which represented their role in degradation." ], "offsets": [ [ 0, 183 ] ] } ]
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[]
[]
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DS.d867
18719855
[ { "id": "DS.d867.s0", "type": "", "text": [ "Treatment with nimbolide resulted in dose- and time-dependent inhibition of growth of BeWo cells with IC(50) values of 2.01 and 1.19 microM for 7 and 24 h respectively, accompanied by downregulation of proliferating cell nuclear antigen." ], "offsets": [ [ 0, 237 ] ] } ]
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[]
[]
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DS.d868
18719891
[ { "id": "DS.d868.s0", "type": "", "text": [ "In all cases, the phenotype of SVQ524 was nearly overcome by the addition of methionine or cobalamin to the plant growth media or by the presence of a copy of the cobO gene in cosmid pMUS756." ], "offsets": [ [ 0, 191 ] ] } ]
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[]
[]
[]
DS.d870
18719969
[ { "id": "DS.d870.s0", "type": "", "text": [ "Obesity increases insulin resistance and glucose intolerance and also exacerbates metabolic abnormalities present in type 2 diabetes." ], "offsets": [ [ 0, 133 ] ] } ]
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[]
[]
[]
DS.d871
18720192
[ { "id": "DS.d871.s0", "type": "", "text": [ "Inhibition of glycogen synthase kinase by curcumin : Investigation by simulated molecular docking and subsequent in vitro/in vivo evaluation." ], "offsets": [ [ 0, 141 ] ] }, { "id": "DS.d871.s1", "type": "", "text": [ "The investigation included simulated docking experiments to fit curcumin within the binding pocket of GSK-3beta followed by experimental in vitro and in vivo validations." ], "offsets": [ [ 142, 312 ] ] }, { "id": "DS.d871.s2", "type": "", "text": [ "Curcumin was found to optimally fit within the binding pocket of GSK-3beta via several attractive interactions with key amino acids." ], "offsets": [ [ 313, 445 ] ] } ]
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"UniProt", "db_id": "Q985P2" }, { "db_name": "UniProt", "db_id": "Q9CHM9" }, { "db_name": "UniProt", "db_id": "Q9CN91" }, { "db_name": "UniProt", "db_id": "Q9EUT5" }, { "db_name": "UniProt", "db_id": "Q9I1V0" }, { "db_name": "UniProt", "db_id": "Q9KDX6" }, { "db_name": "UniProt", "db_id": "Q9KRB6" }, { "db_name": "UniProt", "db_id": "Q9PLC3" }, { "db_name": "UniProt", "db_id": "Q9RNH6" }, { "db_name": "UniProt", "db_id": "Q9RWS1" }, { "db_name": "UniProt", "db_id": "Q9WZZ7" }, { "db_name": "UniProt", "db_id": "Q9Z6V8" } ] }, { "id": "DS.d871.s0.e1", "type": "compound", "text": [ "curcumin" ], "offsets": [ [ 42, 50 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "969516" } ] }, { "id": "DS.d871.s1.e0", "type": "compound", "text": [ "curcumin" ], "offsets": [ [ 206, 214 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "969516" } ] }, { "id": "DS.d871.s1.e1", "type": "protein", "text": [ "GSK-3beta" ], "offsets": [ [ 244, 253 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P18266" }, { "db_name": "UniProt", "db_id": "P49841" }, { "db_name": "UniProt", "db_id": "Q5YJC2" }, { "db_name": "UniProt", "db_id": "Q9WV60" } ] }, { "id": "DS.d871.s2.e0", "type": "compound", "text": [ "Curcumin" ], "offsets": [ [ 313, 321 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "969516" } ] }, { "id": "DS.d871.s2.e1", "type": "protein", "text": [ "GSK-3beta" ], "offsets": [ [ 378, 387 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P18266" }, { "db_name": "UniProt", "db_id": "P49841" }, { "db_name": "UniProt", "db_id": "Q5YJC2" }, { "db_name": "UniProt", "db_id": "Q9WV60" } ] } ]
[]
[]
[ { "id": "DS.d871.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d871.s0.e1", "arg2_id": "DS.d871.s0.e0", "normalized": [] }, { "id": "DS.d871.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d871.s1.e0", "arg2_id": "DS.d871.s1.e1", "normalized": [] }, { "id": "DS.d871.s2.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d871.s2.e0", "arg2_id": "DS.d871.s2.e1", "normalized": [] } ]
DS.d872
18720446
[ { "id": "DS.d872.s0", "type": "", "text": [ "A sample preparation protocol applying a binary matrix-assisted laser desorption/ionization(MALDI) matrix containing alpha-cyano-4-hydroxy cinnamic acid (CHCA) and 2,5-dihydroxy benzoic acid (DHB) on trifluoro acetic acid (TFA) etched latex glove surfaces allowed the direct determination (exact molecular weight) of Hevein, REF and a truncated form of REF (tREF) within nine different brands of natural latex gloves by means of MALDI-TOF-MS in the linear mode." ], "offsets": [ [ 0, 461 ] ] } ]
[ { "id": "DS.d872.s0.e0", "type": "compound", "text": [ "CHCA" ], "offsets": [ [ 154, 158 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5328791" } ] }, { "id": "DS.d872.s0.e1", "type": "compound", "text": [ "benzoic acid" ], "offsets": [ [ 178, 190 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "243" }, { "db_name": "PubChem", "db_id": "167551" } ] }, { "id": "DS.d872.s0.e2", "type": "compound", "text": [ "DHB" ], "offsets": [ [ 192, 195 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "9882105" } ] }, { "id": "DS.d872.s0.e3", "type": "compound", "text": [ "trifluoro acetic acid" ], "offsets": [ [ 200, 221 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6422" } ] }, { "id": "DS.d872.s0.e4", "type": "protein", "text": [ "TFA" ], "offsets": [ [ 223, 226 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q27203" } ] }, { "id": "DS.d872.s0.e5", "type": "protein", "text": [ "Hevein" ], "offsets": [ [ 317, 323 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02877" } ] }, { "id": "DS.d872.s0.e6", "type": "protein", "text": [ "REF" ], "offsets": [ [ 325, 328 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P15252" }, { "db_name": "UniProt", "db_id": "P45951" } ] }, { "id": "DS.d872.s0.e7", "type": "protein", "text": [ "REF" ], "offsets": [ [ 353, 356 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P15252" }, { "db_name": "UniProt", "db_id": "P45951" } ] } ]
[]
[]
[]
DS.d874
18721153
[ { "id": "DS.d874.s0", "type": "", "text": [ "Pathological role of CD44 on NKT cells in carbon tetrachloride-mediated liver injury." ], "offsets": [ [ 0, 85 ] ] }, { "id": "DS.d874.s1", "type": "", "text": [ "Methods: We injected CD44 knock out (KO) or wild type mice with carbon tetrachloride (CCl(4)) and examined the difference of liver injury by immunological or histological analysis." ], "offsets": [ [ 86, 266 ] ] } ]
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[]
[]
[ { "id": "DS.d874.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d874.s0.e1", "arg2_id": "DS.d874.s0.e0", "normalized": [] }, { "id": "DS.d874.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d874.s1.e1", "arg2_id": "DS.d874.s1.e0", "normalized": [] } ]
DS.d875
18721245
[ { "id": "DS.d875.s0", "type": "", "text": [ "Studies using 1-methyl-tryptophan (1-MT), the specific inhibitor of IDO, showed that this enzyme is important in interferon-gamma (IFN-gamma)-dependent inhibition of allergic inflammation in the respiratory airway during immunotherapy." ], "offsets": [ [ 0, 235 ] ] } ]
[ { "id": "DS.d875.s0.e0", "type": "compound", "text": [ "methyl-tryptophan" ], "offsets": [ [ 16, 33 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "98112" } ] }, { "id": "DS.d875.s0.e1", "type": "compound", "text": [ "1-MT" ], "offsets": [ [ 35, 39 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "98112" } ] }, { "id": "DS.d875.s0.e2", "type": "protein", "text": [ "interferon-gamma" ], "offsets": [ [ 113, 129 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q9TTB0" } ] }, { "id": "DS.d875.s0.e3", "type": "protein", "text": [ "IFN-gamma" ], "offsets": [ [ 131, 140 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O35497" }, { "db_name": "UniProt", "db_id": "O35735" }, { "db_name": "UniProt", "db_id": "O57571" }, { "db_name": "UniProt", "db_id": "O57603" }, { "db_name": "UniProt", "db_id": "O57608" }, { "db_name": "UniProt", "db_id": "O73915" }, { "db_name": "UniProt", "db_id": "O77763" }, { "db_name": "UniProt", "db_id": "P01579" }, { "db_name": "UniProt", "db_id": "P01580" }, { "db_name": "UniProt", "db_id": "P01581" }, { "db_name": "UniProt", "db_id": "P07353" }, { "db_name": "UniProt", "db_id": "P17773" }, { "db_name": "UniProt", "db_id": "P17803" }, { "db_name": "UniProt", "db_id": "P28333" }, { "db_name": "UniProt", "db_id": "P28341" }, { "db_name": "UniProt", "db_id": "P30123" }, { "db_name": "UniProt", "db_id": "P42160" }, { "db_name": "UniProt", "db_id": "P42161" }, { "db_name": "UniProt", "db_id": "P42162" }, { "db_name": "UniProt", "db_id": "P46402" }, { "db_name": "UniProt", "db_id": "P49708" }, { "db_name": "UniProt", "db_id": "P63309" }, { "db_name": "UniProt", "db_id": "P63310" }, { "db_name": "UniProt", "db_id": "P63311" }, { "db_name": "UniProt", "db_id": "P79154" }, { "db_name": "UniProt", "db_id": "Q1WM28" }, { "db_name": "UniProt", "db_id": "Q25BC0" }, { "db_name": "UniProt", "db_id": "Q2PE75" }, { "db_name": "UniProt", "db_id": "Q4ZH68" }, { "db_name": "UniProt", "db_id": "Q5CCK0" }, { "db_name": "UniProt", "db_id": "Q5I6S9" }, { "db_name": "UniProt", "db_id": "Q62574" }, { "db_name": "UniProt", "db_id": "Q647G2" }, { "db_name": "UniProt", "db_id": "Q7TSP4" }, { "db_name": "UniProt", "db_id": "Q865W6" }, { "db_name": "UniProt", "db_id": "Q865X1" }, { "db_name": "UniProt", "db_id": "Q865Y4" }, { "db_name": "UniProt", "db_id": "Q866Y6" }, { "db_name": "UniProt", "db_id": "Q8MKF5" }, { "db_name": "UniProt", "db_id": "Q8SPW9" }, { "db_name": "UniProt", "db_id": "Q9QXX2" }, { "db_name": "UniProt", "db_id": "Q9TTB0" }, { "db_name": "UniProt", "db_id": "Q9TV67" }, { "db_name": "UniProt", "db_id": "Q9YGB9" } ] } ]
[]
[]
[ { "id": "DS.d875.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d875.s0.e1", "arg2_id": "DS.d875.s0.e3", "normalized": [] }, { "id": "DS.d875.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d875.s0.e0", "arg2_id": "DS.d875.s0.e3", "normalized": [] }, { "id": "DS.d875.s0.i3", "type": "compound-protein-interaction", "arg1_id": "DS.d875.s0.e1", "arg2_id": "DS.d875.s0.e2", "normalized": [] } ]
DS.d876
18721829
[ { "id": "DS.d876.s0", "type": "", "text": [ "We examined the substrates of cannabinoid-mediated inhibition of both the emetic phases via immunolabeling for serotonin, Substance P, cannabinoid receptors 1 and 2 (CB(1), CB(2)), and the neuronal activation marker Fos in the least shrew (Cryptotis parva)." ], "offsets": [ [ 0, 257 ] ] } ]
[ { "id": "DS.d876.s0.e0", "type": "compound", "text": [ "serotonin" ], "offsets": [ [ 111, 120 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5202" } ] }, { "id": "DS.d876.s0.e1", "type": "protein", "text": [ "Substance P" ], "offsets": [ [ 122, 133 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01289" }, { "db_name": "UniProt", "db_id": "P06767" }, { "db_name": "UniProt", "db_id": "P19850" }, { "db_name": "UniProt", "db_id": "P20366" }, { "db_name": "UniProt", "db_id": "P28498" }, { "db_name": "UniProt", "db_id": "P28499" }, { "db_name": "UniProt", "db_id": "P41333" }, { "db_name": "UniProt", "db_id": "P41539" }, { "db_name": "UniProt", "db_id": "P41540" }, { "db_name": "UniProt", "db_id": "P67932" }, { "db_name": "UniProt", "db_id": "P67933" }, { "db_name": "UniProt", "db_id": "Q60541" } ] }, { "id": "DS.d876.s0.e2", "type": "protein", "text": [ "cannabinoid receptors 1" ], "offsets": [ [ 135, 158 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O02777" }, { "db_name": "UniProt", "db_id": "P20272" }, { "db_name": "UniProt", "db_id": "P21554" }, { "db_name": "UniProt", "db_id": "P47746" }, { "db_name": "UniProt", "db_id": "P56971" }, { "db_name": "UniProt", "db_id": "Q333S9" }, { "db_name": "UniProt", "db_id": "Q5IS73" }, { "db_name": "UniProt", "db_id": "Q71SP5" }, { "db_name": "UniProt", "db_id": "Q801M1" }, { "db_name": "UniProt", "db_id": "Q9PUI7" } ] }, { "id": "DS.d876.s0.e3", "type": "protein", "text": [ "Fos" ], "offsets": [ [ 216, 219 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01101" }, { "db_name": "UniProt", "db_id": "P12841" }, { "db_name": "UniProt", "db_id": "Q56415" } ] } ]
[]
[]
[]
DS.d877
18722097
[ { "id": "DS.d877.s0", "type": "", "text": [ "To observe the inhibitory effects of TSP-1 functional fragments, critical for CD36 binding, on the activation of L-TGF-beta1, we isolated alveolar macrophages from Wistar rat lungs 7 days after bleomycin administration (5mg/kg body weight) and cultured the cells with or without TSP-1 functional or control fragments." ], "offsets": [ [ 0, 317 ] ] } ]
[ { "id": "DS.d877.s0.e0", "type": "protein", "text": [ "TSP-1" ], "offsets": [ [ 37, 42 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P11032" }, { "db_name": "UniProt", "db_id": "Q28178" } ] }, { "id": "DS.d877.s0.e1", "type": "protein", "text": [ "CD36" ], "offsets": [ [ 78, 82 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P16671" }, { "db_name": "UniProt", "db_id": "P26201" }, { "db_name": "UniProt", "db_id": "P70110" } ] }, { "id": "DS.d877.s0.e2", "type": "protein", "text": [ "TGF-beta1" ], "offsets": [ [ 115, 124 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O19011" }, { "db_name": "UniProt", "db_id": "O93449" }, { "db_name": "UniProt", "db_id": "P01137" }, { "db_name": "UniProt", "db_id": "P04202" }, { "db_name": "UniProt", "db_id": "P07200" }, { "db_name": "UniProt", "db_id": "P09531" }, { "db_name": "UniProt", "db_id": "P09533" }, { "db_name": "UniProt", "db_id": "P16176" }, { "db_name": "UniProt", "db_id": "P17246" }, { "db_name": "UniProt", "db_id": "P18341" }, { "db_name": "UniProt", "db_id": "P50414" }, { "db_name": "UniProt", "db_id": "P54831" }, { "db_name": "UniProt", "db_id": "Q38HS2" }, { "db_name": "UniProt", "db_id": "Q9PTQ2" }, { "db_name": "UniProt", "db_id": "Q9Z1Y6" } ] }, { "id": "DS.d877.s0.e3", "type": "compound", "text": [ "bleomycin" ], "offsets": [ [ 194, 203 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "456190" }, { "db_name": "PubChem", "db_id": "5360373" }, { "db_name": "PubChem", "db_id": "5460769" } ] }, { "id": "DS.d877.s0.e4", "type": "protein", "text": [ "TSP-1" ], "offsets": [ [ 279, 284 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P11032" }, { "db_name": "UniProt", "db_id": "Q28178" } ] } ]
[]
[]
[]
DS.d878
18722104
[ { "id": "DS.d878.s0", "type": "", "text": [ "The pEREGFP9 vector was delivered to a single MCF-7 using a nanoneedle and the effect of ICI 182,780, which is an antagonist of estrogen, was observed using the GFP expression level." ], "offsets": [ [ 0, 182 ] ] }, { "id": "DS.d878.s1", "type": "", "text": [ "By ICI 182,780 treatment, the fluorescence intensity of the GFP was decreased by 30-50% within 24h." ], "offsets": [ [ 183, 282 ] ] } ]
[ { "id": "DS.d878.s0.e0", "type": "compound", "text": [ "ICI 182,780" ], "offsets": [ [ 89, 100 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "104741" } ] }, { "id": "DS.d878.s0.e1", "type": "protein", "text": [ "GFP" ], "offsets": [ [ 8, 11 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P42212" } ] }, { "id": "DS.d878.s1.e0", "type": "compound", "text": [ "ICI 182,780" ], "offsets": [ [ 186, 197 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "104741" } ] }, { "id": "DS.d878.s1.e1", "type": "protein", "text": [ "GFP" ], "offsets": [ [ 243, 246 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P42212" } ] } ]
[]
[]
[ { "id": "DS.d878.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d878.s1.e0", "arg2_id": "DS.d878.s1.e1", "normalized": [] } ]
DS.d879
18722114
[ { "id": "DS.d879.s0", "type": "", "text": [ "Effect of different cellulase dosages on cell viability and ethanol production by Kluyveromyces marxianus in SSF processes." ], "offsets": [ [ 0, 123 ] ] }, { "id": "DS.d879.s1", "type": "", "text": [ "This study was aimed to study the effect of commercial cellulases (Celluclast 1.5 LFG) on Kluyveromyces marxianus CECT 10875 growth and ethanol production in SSF processes." ], "offsets": [ [ 124, 296 ] ] } ]
[ { "id": "DS.d879.s0.e0", "type": "protein", "text": [ "cellulase" ], "offsets": [ [ 20, 29 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P07981" }, { "db_name": "UniProt", "db_id": "P07982" }, { "db_name": "UniProt", "db_id": "P07983" }, { "db_name": "UniProt", "db_id": "P10474" }, { "db_name": "UniProt", "db_id": "P10475" }, { "db_name": "UniProt", "db_id": "P10476" }, { "db_name": "UniProt", "db_id": "P13933" }, { "db_name": "UniProt", "db_id": "P15329" }, { "db_name": "UniProt", "db_id": "P15704" }, { "db_name": "UniProt", "db_id": "P16216" }, { "db_name": "UniProt", "db_id": "P17974" }, { "db_name": "UniProt", "db_id": "P18126" }, { "db_name": "UniProt", "db_id": "P18336" }, { "db_name": "UniProt", "db_id": "P19487" }, { "db_name": "UniProt", "db_id": "P21833" }, { "db_name": "UniProt", "db_id": "P21834" }, { "db_name": "UniProt", "db_id": "P22533" }, { "db_name": "UniProt", "db_id": "P22669" }, { "db_name": "UniProt", "db_id": "P22699" }, { "db_name": "UniProt", "db_id": "P23548" }, { "db_name": "UniProt", "db_id": "P23549" }, { "db_name": "UniProt", "db_id": "P23665" }, { "db_name": "UniProt", "db_id": "P27035" }, { "db_name": "UniProt", "db_id": "P29019" }, { "db_name": "UniProt", "db_id": "P37651" }, { "db_name": "UniProt", "db_id": "P37696" }, { "db_name": "UniProt", "db_id": "P45699" }, { "db_name": "UniProt", "db_id": "P46236" }, { "db_name": "UniProt", "db_id": "P46237" }, { "db_name": "UniProt", "db_id": "P46239" }, { "db_name": "UniProt", "db_id": "P58599" }, { "db_name": "UniProt", "db_id": "P58935" }, { "db_name": "UniProt", "db_id": "P81190" }, { "db_name": "UniProt", "db_id": "P82186" }, { "db_name": "UniProt", "db_id": "P84194" }, { "db_name": "UniProt", "db_id": "P84196" }, { "db_name": "UniProt", "db_id": "Q05622" }, { "db_name": "UniProt", "db_id": "Q12622" }, { "db_name": "UniProt", "db_id": "Q12714" }, { "db_name": "UniProt", "db_id": "Q8RSY9" }, { "db_name": "UniProt", "db_id": "Q8X5L9" }, { "db_name": "UniProt", "db_id": "Q8Z289" }, { "db_name": "UniProt", "db_id": "Q8ZLB7" } ] }, { "id": "DS.d879.s0.e1", "type": "compound", "text": [ "ethanol" ], "offsets": [ [ 60, 67 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "702" } ] }, { "id": "DS.d879.s1.e0", "type": "protein", "text": [ "cellulases" ], "offsets": [ [ 179, 189 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P07981" }, { "db_name": "UniProt", "db_id": "P07982" }, { "db_name": "UniProt", "db_id": "P07983" }, { "db_name": "UniProt", "db_id": "P10474" }, { "db_name": "UniProt", "db_id": "P10475" }, { "db_name": "UniProt", "db_id": "P10476" }, { "db_name": "UniProt", "db_id": "P13933" }, { "db_name": "UniProt", "db_id": "P15329" }, { "db_name": "UniProt", "db_id": "P15704" }, { "db_name": "UniProt", "db_id": "P16216" }, { "db_name": "UniProt", "db_id": "P17974" }, { "db_name": "UniProt", "db_id": "P18126" }, { "db_name": "UniProt", "db_id": "P18336" }, { "db_name": "UniProt", "db_id": "P19487" }, { "db_name": "UniProt", "db_id": "P21833" }, { "db_name": "UniProt", "db_id": "P21834" }, { "db_name": "UniProt", "db_id": "P22533" }, { "db_name": "UniProt", "db_id": "P22669" }, { "db_name": "UniProt", "db_id": "P22699" }, { "db_name": "UniProt", "db_id": "P23548" }, { "db_name": "UniProt", "db_id": "P23549" }, { "db_name": "UniProt", "db_id": "P23665" }, { "db_name": "UniProt", "db_id": "P27035" }, { "db_name": "UniProt", "db_id": "P29019" }, { "db_name": "UniProt", "db_id": "P37651" }, { "db_name": "UniProt", "db_id": "P37696" }, { "db_name": "UniProt", "db_id": "P45699" }, { "db_name": "UniProt", "db_id": "P46236" }, { "db_name": "UniProt", "db_id": "P46237" }, { "db_name": "UniProt", "db_id": "P46239" }, { "db_name": "UniProt", "db_id": "P58599" }, { "db_name": "UniProt", "db_id": "P58935" }, { "db_name": "UniProt", "db_id": "P81190" }, { "db_name": "UniProt", "db_id": "P82186" }, { "db_name": "UniProt", "db_id": "P84194" }, { "db_name": "UniProt", "db_id": "P84196" }, { "db_name": "UniProt", "db_id": "Q05622" }, { "db_name": "UniProt", "db_id": "Q12622" }, { "db_name": "UniProt", "db_id": "Q12714" }, { "db_name": "UniProt", "db_id": "Q8RSY9" }, { "db_name": "UniProt", "db_id": "Q8X5L9" }, { "db_name": "UniProt", "db_id": "Q8Z289" }, { "db_name": "UniProt", "db_id": "Q8ZLB7" } ] }, { "id": "DS.d879.s1.e1", "type": "compound", "text": [ "ethanol" ], "offsets": [ [ 260, 267 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "702" } ] } ]
[]
[]
[ { "id": "DS.d879.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d879.s0.e1", "arg2_id": "DS.d879.s0.e0", "normalized": [] }, { "id": "DS.d879.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d879.s1.e1", "arg2_id": "DS.d879.s1.e0", "normalized": [] } ]
DS.d881
18722490
[ { "id": "DS.d881.s0", "type": "", "text": [ "Crustacean hyperglycemic hormone (CHH) not only plays an important role in the modulation of hemolymph glucose level but also functions in other biological events including molting, reproduction and stress response." ], "offsets": [ [ 0, 215 ] ] } ]
[ { "id": "DS.d881.s0.e0", "type": "protein", "text": [ "Crustacean hyperglycemic hormone" ], "offsets": [ [ 0, 32 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O77220" }, { "db_name": "UniProt", "db_id": "P14944" }, { "db_name": "UniProt", "db_id": "P30814" }, { "db_name": "UniProt", "db_id": "P55845" }, { "db_name": "UniProt", "db_id": "P56687" }, { "db_name": "UniProt", "db_id": "P59685" }, { "db_name": "UniProt", "db_id": "P81032" }, { "db_name": "UniProt", "db_id": "P83800" }, { "db_name": "UniProt", "db_id": "Q25588" }, { "db_name": "UniProt", "db_id": "Q25589" }, { "db_name": "UniProt", "db_id": "Q25683" }, { "db_name": "UniProt", "db_id": "Q26181" } ] }, { "id": "DS.d881.s0.e1", "type": "protein", "text": [ "CHH" ], "offsets": [ [ 34, 37 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O77220" }, { "db_name": "UniProt", "db_id": "P14944" }, { "db_name": "UniProt", "db_id": "P30814" }, { "db_name": "UniProt", "db_id": "P55845" }, { "db_name": "UniProt", "db_id": "P56687" }, { "db_name": "UniProt", "db_id": "P59685" }, { "db_name": "UniProt", "db_id": "P81032" }, { "db_name": "UniProt", "db_id": "P83800" }, { "db_name": "UniProt", "db_id": "Q25588" }, { "db_name": "UniProt", "db_id": "Q25589" }, { "db_name": "UniProt", "db_id": "Q25683" }, { "db_name": "UniProt", "db_id": "Q26181" } ] }, { "id": "DS.d881.s0.e2", "type": "compound", "text": [ "glucose" ], "offsets": [ [ 103, 110 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "206" }, { "db_name": "PubChem", "db_id": "5793" }, { "db_name": "PubChem", "db_id": "64689" }, { "db_name": "PubChem", "db_id": "79025" } ] } ]
[]
[]
[ { "id": "DS.d881.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d881.s0.e2", "arg2_id": "DS.d881.s0.e1", "normalized": [] }, { "id": "DS.d881.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d881.s0.e2", "arg2_id": "DS.d881.s0.e0", "normalized": [] } ]
DS.d882
18722763
[ { "id": "DS.d882.s0", "type": "", "text": [ "As a proof-of-concept, Concanavalin A-coated QDs (ConA-QDs) and dextran-coated AuNPs (Dex-AuNPs) were used to detect the mannosylated proteins." ], "offsets": [ [ 0, 143 ] ] }, { "id": "DS.d882.s1", "type": "", "text": [ "As a result, the PL intensity of QDs was found to be linearly correlated with the concentration and the number of glycan moiety of the glycoprotein." ], "offsets": [ [ 144, 292 ] ] } ]
[ { "id": "DS.d882.s0.e0", "type": "protein", "text": [ "Concanavalin A" ], "offsets": [ [ 23, 37 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P81460" }, { "db_name": "UniProt", "db_id": "P81461" } ] }, { "id": "DS.d882.s0.e1", "type": "protein", "text": [ "ConA" ], "offsets": [ [ 50, 54 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02866" }, { "db_name": "UniProt", "db_id": "P14894" }, { "db_name": "UniProt", "db_id": "P81460" }, { "db_name": "UniProt", "db_id": "P81461" } ] }, { "id": "DS.d882.s0.e2", "type": "compound", "text": [ "dextran" ], "offsets": [ [ 64, 71 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "4125253" }, { "db_name": "PubChem", "db_id": "5460037" } ] }, { "id": "DS.d882.s1.e0", "type": "compound", "text": [ "glycan" ], "offsets": [ [ 258, 264 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "871" } ] }, { "id": "DS.d882.s1.e1", "type": "protein", "text": [ "glycoprotein" ], "offsets": [ [ 279, 291 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P08163" } ] } ]
[]
[]
[ { "id": "DS.d882.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d882.s1.e0", "arg2_id": "DS.d882.s1.e1", "normalized": [] } ]
DS.d883
18723022
[ { "id": "DS.d883.s0", "type": "", "text": [ "We demonstrate for the first time that several developmental stages of the human parasite Schistosoma mansoni express arginase, which is responsible for the hydrolysis of l-arginine to l-ornithine and urea." ], "offsets": [ [ 0, 206 ] ] } ]
[ { "id": "DS.d883.s0.e0", "type": "protein", "text": [ "arginase" ], "offsets": [ [ 118, 126 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O49046" }, { "db_name": "UniProt", "db_id": "P00812" }, { "db_name": "UniProt", "db_id": "P0A2X9" }, { "db_name": "UniProt", "db_id": "P0A2Y0" }, { "db_name": "UniProt", "db_id": "P0A2Y1" }, { "db_name": "UniProt", "db_id": "P14012" }, { "db_name": "UniProt", "db_id": "P33280" }, { "db_name": "UniProt", "db_id": "P37818" }, { "db_name": "UniProt", "db_id": "P39138" }, { "db_name": "UniProt", "db_id": "P40906" }, { "db_name": "UniProt", "db_id": "P46637" }, { "db_name": "UniProt", "db_id": "P53608" }, { "db_name": "UniProt", "db_id": "P60086" }, { "db_name": "UniProt", "db_id": "P60087" }, { "db_name": "UniProt", "db_id": "P60088" }, { "db_name": "UniProt", "db_id": "Q10066" }, { "db_name": "UniProt", "db_id": "Q12611" }, { "db_name": "UniProt", "db_id": "Q1E180" }, { "db_name": "UniProt", "db_id": "Q6G7E9" }, { "db_name": "UniProt", "db_id": "Q6GER3" }, { "db_name": "UniProt", "db_id": "Q74ZW4" }, { "db_name": "UniProt", "db_id": "Q7M0Z3" }, { "db_name": "UniProt", "db_id": "Q8NVE3" } ] }, { "id": "DS.d883.s0.e1", "type": "compound", "text": [ "arginine" ], "offsets": [ [ 173, 181 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "232" }, { "db_name": "PubChem", "db_id": "4367" }, { "db_name": "PubChem", "db_id": "6322" } ] }, { "id": "DS.d883.s0.e2", "type": "compound", "text": [ "l-ornithine" ], "offsets": [ [ 185, 196 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6262" } ] }, { "id": "DS.d883.s0.e3", "type": "compound", "text": [ "urea" ], "offsets": [ [ 201, 205 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1176" }, { "db_name": "PubChem", "db_id": "265993" } ] } ]
[]
[]
[ { "id": "DS.d883.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d883.s0.e1", "arg2_id": "DS.d883.s0.e0", "normalized": [] }, { "id": "DS.d883.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d883.s0.e3", "arg2_id": "DS.d883.s0.e0", "normalized": [] }, { "id": "DS.d883.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d883.s0.e2", "arg2_id": "DS.d883.s0.e0", "normalized": [] } ]
DS.d884
18723107
[ { "id": "DS.d884.s0", "type": "", "text": [ "To overcome this limitation we turned to the yeast Pichia stipitis, which naturally produces xylitol, as a source of xylulokinase (Xyl3)." ], "offsets": [ [ 0, 137 ] ] }, { "id": "DS.d884.s1", "type": "", "text": [ "We examined the effects of plasmid-based expression of Xyl3 versus XylB on growth and xylitol production by engineered E. coli strains." ], "offsets": [ [ 138, 273 ] ] } ]
[ { "id": "DS.d884.s0.e0", "type": "compound", "text": [ "xylitol" ], "offsets": [ [ 93, 100 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6912" } ] }, { "id": "DS.d884.s0.e1", "type": "protein", "text": [ "xylulokinase" ], "offsets": [ [ 117, 129 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O75191" }, { "db_name": "UniProt", "db_id": "P09099" }, { "db_name": "UniProt", "db_id": "P12867" }, { "db_name": "UniProt", "db_id": "P21939" }, { "db_name": "UniProt", "db_id": "P26909" }, { "db_name": "UniProt", "db_id": "P27155" }, { "db_name": "UniProt", "db_id": "P27156" }, { "db_name": "UniProt", "db_id": "P29444" }, { "db_name": "UniProt", "db_id": "P35850" }, { "db_name": "UniProt", "db_id": "P39211" }, { "db_name": "UniProt", "db_id": "P42826" }, { "db_name": "UniProt", "db_id": "P44401" }, { "db_name": "UniProt", "db_id": "P54271" }, { "db_name": "UniProt", "db_id": "Q3MIF4" }, { "db_name": "UniProt", "db_id": "Q3SYZ6" }, { "db_name": "UniProt", "db_id": "Q3TNA1" }, { "db_name": "UniProt", "db_id": "Q5R830" }, { "db_name": "UniProt", "db_id": "Q9CFG8" }, { "db_name": "UniProt", "db_id": "Q9RK00" } ] }, { "id": "DS.d884.s1.e0", "type": "protein", "text": [ "XylB" ], "offsets": [ [ 205, 209 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O30360" }, { "db_name": "UniProt", "db_id": "P09099" }, { "db_name": "UniProt", "db_id": "P12867" }, { "db_name": "UniProt", "db_id": "P21939" }, { "db_name": "UniProt", "db_id": "P26909" }, { "db_name": "UniProt", "db_id": "P27155" }, { "db_name": "UniProt", "db_id": "P27156" }, { "db_name": "UniProt", "db_id": "P29444" }, { "db_name": "UniProt", "db_id": "P35850" }, { "db_name": "UniProt", "db_id": "P39211" }, { "db_name": "UniProt", "db_id": "P39849" }, { "db_name": "UniProt", "db_id": "P44401" }, { "db_name": "UniProt", "db_id": "P45982" }, { "db_name": "UniProt", "db_id": "P54271" }, { "db_name": "UniProt", "db_id": "Q5HL88" }, { "db_name": "UniProt", "db_id": "Q8CR47" }, { "db_name": "UniProt", "db_id": "Q9CFG8" }, { "db_name": "UniProt", "db_id": "Q9RK00" } ] }, { "id": "DS.d884.s1.e1", "type": "compound", "text": [ "xylitol" ], "offsets": [ [ 224, 231 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6912" } ] } ]
[]
[]
[ { "id": "DS.d884.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d884.s0.e0", "arg2_id": "DS.d884.s0.e1", "normalized": [] } ]
DS.d885
18723121
[ { "id": "DS.d885.s0", "type": "", "text": [ "Behavioral and biochemical responses including filtering rates, key phase I, II and antioxidant enzymes and levels of metallothioneins, glutathione, lipid peroxidation and DNA strand breaks were determined in digestive glands of mussels after being exposed to sublethal levels of mercury chloride, methyl mercury, cadmium and Aroclor 1260 during 5 days." ], "offsets": [ [ 0, 353 ] ] } ]
[ { "id": "DS.d885.s0.e0", "type": "protein", "text": [ "metallothioneins" ], "offsets": [ [ 118, 134 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O02033" }, { "db_name": "UniProt", "db_id": "O13257" }, { "db_name": "UniProt", "db_id": "O18842" }, { "db_name": "UniProt", "db_id": "O42152" }, { "db_name": "UniProt", "db_id": "O93571" }, { "db_name": "UniProt", "db_id": "P02807" }, { "db_name": "UniProt", "db_id": "P04358" }, { "db_name": "UniProt", "db_id": "P07216" }, { "db_name": "UniProt", "db_id": "P08002" }, { "db_name": "UniProt", "db_id": "P23038" }, { "db_name": "UniProt", "db_id": "P25127" }, { "db_name": "UniProt", "db_id": "P25128" }, { "db_name": "UniProt", "db_id": "P30331" }, { "db_name": "UniProt", "db_id": "P30565" }, { "db_name": "UniProt", "db_id": "P51902" }, { "db_name": "UniProt", "db_id": "P52723" }, { "db_name": "UniProt", "db_id": "P52725" }, { "db_name": "UniProt", "db_id": "P52726" }, { "db_name": "UniProt", "db_id": "P52728" }, { "db_name": "UniProt", "db_id": "P55945" }, { "db_name": "UniProt", "db_id": "P55946" }, { "db_name": "UniProt", "db_id": "P55948" }, { "db_name": "UniProt", "db_id": "P55951" }, { "db_name": "UniProt", "db_id": "P55952" }, { "db_name": "UniProt", "db_id": "P55953" }, { "db_name": "UniProt", "db_id": "P68494" }, { "db_name": "UniProt", "db_id": "P68495" }, { "db_name": "UniProt", "db_id": "P68497" }, { "db_name": "UniProt", "db_id": "P68498" }, { "db_name": "UniProt", "db_id": "P68499" }, { "db_name": "UniProt", "db_id": "P80367" }, { "db_name": "UniProt", "db_id": "P80593" }, { "db_name": "UniProt", "db_id": "P84865" }, { "db_name": "UniProt", "db_id": "Q05890" }, { "db_name": "UniProt", "db_id": "Q6J1T3" }, { "db_name": "UniProt", "db_id": "Q6S4N8" }, { "db_name": "UniProt", "db_id": "Q6XUW5" }, { "db_name": "UniProt", "db_id": "Q708T3" }, { "db_name": "UniProt", "db_id": "Q7ZZP9" }, { "db_name": "UniProt", "db_id": "Q800D3" }, { "db_name": "UniProt", "db_id": "Q8UVY1" }, { "db_name": "UniProt", "db_id": "Q94550" }, { "db_name": "UniProt", "db_id": "Q9IB50" }, { "db_name": "UniProt", "db_id": "Q9U568" } ] }, { "id": "DS.d885.s0.e1", "type": "compound", "text": [ "glutathione" ], "offsets": [ [ 136, 147 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "124886" } ] } ]
[]
[]
[]
DS.d886
18723336
[ { "id": "DS.d886.s0", "type": "", "text": [ "In this study, a representative FRET system (CFP donor and YFP acceptor) is compared with the BRET(2) system (Renilla luciferase donor, green fluorescent protein (2) (GFP (2)) acceptor and coelenterazine 400a substrate)." ], "offsets": [ [ 0, 220 ] ] } ]
[ { "id": "DS.d886.s0.e0", "type": "protein", "text": [ "CFP" ], "offsets": [ [ 45, 48 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P27918" }, { "db_name": "UniProt", "db_id": "Q5RBP8" }, { "db_name": "UniProt", "db_id": "Q64181" } ] }, { "id": "DS.d886.s0.e1", "type": "protein", "text": [ "YFP" ], "offsets": [ [ 59, 62 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P21578" } ] }, { "id": "DS.d886.s0.e2", "type": "protein", "text": [ "luciferase" ], "offsets": [ [ 118, 128 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P08659" }, { "db_name": "UniProt", "db_id": "P13129" }, { "db_name": "UniProt", "db_id": "Q01158" }, { "db_name": "UniProt", "db_id": "Q26304" }, { "db_name": "UniProt", "db_id": "Q27757" } ] }, { "id": "DS.d886.s0.e3", "type": "protein", "text": [ "green fluorescent protein" ], "offsets": [ [ 136, 161 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P42212" } ] }, { "id": "DS.d886.s0.e4", "type": "protein", "text": [ "GFP" ], "offsets": [ [ 167, 170 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P42212" } ] }, { "id": "DS.d886.s0.e5", "type": "compound", "text": [ "coelenterazine 400a" ], "offsets": [ [ 189, 208 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "22832089" } ] } ]
[]
[]
[]
DS.d887
18723342
[ { "id": "DS.d887.s0", "type": "", "text": [ "If no pretreatment applied, hydrolyses of the textiles by cellulase and beta-glucosidase for 24 h followed by simultaneous saccharification and fermentation (SSF) in 4 days, resulted in 0.140-0.145 g ethanol/g textiles, which was 25-26% of the corresponding theoretical yield." ], "offsets": [ [ 0, 276 ] ] } ]
[ { "id": "DS.d887.s0.e0", "type": "protein", "text": [ "cellulase" ], "offsets": [ [ 58, 67 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P07981" }, { "db_name": "UniProt", "db_id": "P07982" }, { "db_name": "UniProt", "db_id": "P07983" }, { "db_name": "UniProt", "db_id": "P10474" }, { "db_name": "UniProt", "db_id": "P10475" }, { "db_name": "UniProt", "db_id": "P10476" }, { "db_name": "UniProt", "db_id": "P13933" }, { "db_name": "UniProt", "db_id": "P15329" }, { "db_name": "UniProt", "db_id": "P15704" }, { "db_name": "UniProt", "db_id": "P16216" }, { "db_name": "UniProt", "db_id": "P17974" }, { "db_name": "UniProt", "db_id": "P18126" }, { "db_name": "UniProt", "db_id": "P18336" }, { "db_name": "UniProt", "db_id": "P19487" }, { "db_name": "UniProt", "db_id": "P21833" }, { "db_name": "UniProt", "db_id": "P21834" }, { "db_name": "UniProt", "db_id": "P22533" }, { "db_name": "UniProt", "db_id": "P22669" }, { "db_name": "UniProt", "db_id": "P22699" }, { "db_name": "UniProt", "db_id": "P23548" }, { "db_name": "UniProt", "db_id": "P23549" }, { "db_name": "UniProt", "db_id": "P23665" }, { "db_name": "UniProt", "db_id": "P27035" }, { "db_name": "UniProt", "db_id": "P29019" }, { "db_name": "UniProt", "db_id": "P37651" }, { "db_name": "UniProt", "db_id": "P37696" }, { "db_name": "UniProt", "db_id": "P45699" }, { "db_name": "UniProt", "db_id": "P46236" }, { "db_name": "UniProt", "db_id": "P46237" }, { "db_name": "UniProt", "db_id": "P46239" }, { "db_name": "UniProt", "db_id": "P58599" }, { "db_name": "UniProt", "db_id": "P58935" }, { "db_name": "UniProt", "db_id": "P81190" }, { "db_name": "UniProt", "db_id": "P82186" }, { "db_name": "UniProt", "db_id": "P84194" }, { "db_name": "UniProt", "db_id": "P84196" }, { "db_name": "UniProt", "db_id": "Q05622" }, { "db_name": "UniProt", "db_id": "Q12622" }, { "db_name": "UniProt", "db_id": "Q12714" }, { "db_name": "UniProt", "db_id": "Q8RSY9" }, { "db_name": "UniProt", "db_id": "Q8X5L9" }, { "db_name": "UniProt", "db_id": "Q8Z289" }, { "db_name": "UniProt", "db_id": "Q8ZLB7" } ] }, { "id": "DS.d887.s0.e1", "type": "protein", "text": [ "beta-glucosidase" ], "offsets": [ [ 72, 88 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P12614" }, { "db_name": "UniProt", "db_id": "P15885" }, { "db_name": "UniProt", "db_id": "P27034" }, { "db_name": "UniProt", "db_id": "P29091" }, { "db_name": "UniProt", "db_id": "P40740" }, { "db_name": "UniProt", "db_id": "Q03506" }, { "db_name": "UniProt", "db_id": "Q46684" } ] }, { "id": "DS.d887.s0.e2", "type": "compound", "text": [ "ethanol" ], "offsets": [ [ 200, 207 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "702" } ] } ]
[]
[]
[ { "id": "DS.d887.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d887.s0.e2", "arg2_id": "DS.d887.s0.e1", "normalized": [] }, { "id": "DS.d887.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d887.s0.e2", "arg2_id": "DS.d887.s0.e0", "normalized": [] } ]
DS.d888
18723440
[ { "id": "DS.d888.s0", "type": "", "text": [ "In cystic fibrosis, this equilibrium is disrupted by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene resulting in the absence of functional CFTR protein, which in turn results in deficient cAMP-dependent Cl (-) secretion and predominant Na (+) absorption." ], "offsets": [ [ 0, 288 ] ] } ]
[ { "id": "DS.d888.s0.e0", "type": "protein", "text": [ "cystic fibrosis transmembrane conductance regulator" ], "offsets": [ [ 70, 121 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P13569" }, { "db_name": "UniProt", "db_id": "P26361" }, { "db_name": "UniProt", "db_id": "P26362" }, { "db_name": "UniProt", "db_id": "P26363" }, { "db_name": "UniProt", "db_id": "P34158" }, { "db_name": "UniProt", "db_id": "P35071" }, { "db_name": "UniProt", "db_id": "Q00552" }, { "db_name": "UniProt", "db_id": "Q00553" }, { "db_name": "UniProt", "db_id": "Q00554" }, { "db_name": "UniProt", "db_id": "Q00555" }, { "db_name": "UniProt", "db_id": "Q07DV2" }, { "db_name": "UniProt", "db_id": "Q07DW5" }, { "db_name": "UniProt", "db_id": "Q07DX5" }, { "db_name": "UniProt", "db_id": "Q07DY5" }, { "db_name": "UniProt", "db_id": "Q07DZ6" }, { "db_name": "UniProt", "db_id": "Q07E16" }, { "db_name": "UniProt", "db_id": "Q07E42" }, { "db_name": "UniProt", "db_id": "Q09YH0" }, { "db_name": "UniProt", "db_id": "Q09YJ4" }, { "db_name": "UniProt", "db_id": "Q09YK5" }, { "db_name": "UniProt", "db_id": "Q108U0" }, { "db_name": "UniProt", "db_id": "Q2IBA1" }, { "db_name": "UniProt", "db_id": "Q2IBB3" }, { "db_name": "UniProt", "db_id": "Q2IBE4" }, { "db_name": "UniProt", "db_id": "Q2IBF6" }, { "db_name": "UniProt", "db_id": "Q2QL74" }, { "db_name": "UniProt", "db_id": "Q2QL83" }, { "db_name": "UniProt", "db_id": "Q2QLA3" }, { "db_name": "UniProt", "db_id": "Q2QLB4" }, { "db_name": "UniProt", "db_id": "Q2QLC5" }, { "db_name": "UniProt", "db_id": "Q2QLE5" }, { "db_name": "UniProt", "db_id": "Q2QLF9" }, { "db_name": "UniProt", "db_id": "Q2QLH0" }, { "db_name": "UniProt", "db_id": "Q5D1Z7" }, { "db_name": "UniProt", "db_id": "Q5U820" }, { "db_name": "UniProt", "db_id": "Q6PQZ2" }, { "db_name": "UniProt", "db_id": "Q7JII7" }, { "db_name": "UniProt", "db_id": "Q7JII8" }, { "db_name": "UniProt", "db_id": "Q9TSP5" }, { "db_name": "UniProt", "db_id": "Q9TUQ2" } ] }, { "id": "DS.d888.s0.e1", "type": "protein", "text": [ "CFTR" ], "offsets": [ [ 123, 127 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P13569" }, { "db_name": "UniProt", "db_id": "P26361" }, { "db_name": "UniProt", "db_id": "P26362" }, { "db_name": "UniProt", "db_id": "P26363" }, { "db_name": "UniProt", "db_id": "P34158" }, { "db_name": "UniProt", "db_id": "P35071" }, { "db_name": "UniProt", "db_id": "Q00552" }, { "db_name": "UniProt", "db_id": "Q00553" }, { "db_name": "UniProt", "db_id": "Q00554" }, { "db_name": "UniProt", "db_id": "Q00555" }, { "db_name": "UniProt", "db_id": "Q07DV2" }, { "db_name": "UniProt", "db_id": "Q07DW5" }, { "db_name": "UniProt", "db_id": "Q07DX5" }, { "db_name": "UniProt", "db_id": "Q07DY5" }, { "db_name": "UniProt", "db_id": "Q07DZ6" }, { "db_name": "UniProt", "db_id": "Q07E16" }, { "db_name": "UniProt", "db_id": "Q07E42" }, { "db_name": "UniProt", "db_id": "Q09YH0" }, { "db_name": "UniProt", "db_id": "Q09YJ4" }, { "db_name": "UniProt", "db_id": "Q09YK5" }, { "db_name": "UniProt", "db_id": "Q108U0" }, { "db_name": "UniProt", "db_id": "Q2IBA1" }, { "db_name": "UniProt", "db_id": "Q2IBB3" }, { "db_name": "UniProt", "db_id": "Q2IBE4" }, { "db_name": "UniProt", "db_id": "Q2IBF6" }, { "db_name": "UniProt", "db_id": "Q2QL74" }, { "db_name": "UniProt", "db_id": "Q2QL83" }, { "db_name": "UniProt", "db_id": "Q2QLA3" }, { "db_name": "UniProt", "db_id": "Q2QLB4" }, { "db_name": "UniProt", "db_id": "Q2QLC5" }, { "db_name": "UniProt", "db_id": "Q2QLE5" }, { "db_name": "UniProt", "db_id": "Q2QLF9" }, { "db_name": "UniProt", "db_id": "Q2QLH0" }, { "db_name": "UniProt", "db_id": "Q5D1Z7" }, { "db_name": "UniProt", "db_id": "Q5U820" }, { "db_name": "UniProt", "db_id": "Q6PQZ2" }, { "db_name": "UniProt", "db_id": "Q7JII7" }, { "db_name": "UniProt", "db_id": "Q7JII8" }, { "db_name": "UniProt", "db_id": "Q9TSP5" }, { "db_name": "UniProt", "db_id": "Q9TUQ2" } ] }, { "id": "DS.d888.s0.e2", "type": "protein", "text": [ "CFTR" ], "offsets": [ [ 173, 177 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P13569" }, { "db_name": "UniProt", "db_id": "P26361" }, { "db_name": "UniProt", "db_id": "P26362" }, { "db_name": "UniProt", "db_id": "P26363" }, { "db_name": "UniProt", "db_id": "P34158" }, { "db_name": "UniProt", "db_id": "P35071" }, { "db_name": "UniProt", "db_id": "Q00552" }, { "db_name": "UniProt", "db_id": "Q00553" }, { "db_name": "UniProt", "db_id": "Q00554" }, { "db_name": "UniProt", "db_id": "Q00555" }, { "db_name": "UniProt", "db_id": "Q07DV2" }, { "db_name": "UniProt", "db_id": "Q07DW5" }, { "db_name": "UniProt", "db_id": "Q07DX5" }, { "db_name": "UniProt", "db_id": "Q07DY5" }, { "db_name": "UniProt", "db_id": "Q07DZ6" }, { "db_name": "UniProt", "db_id": "Q07E16" }, { "db_name": "UniProt", "db_id": "Q07E42" }, { "db_name": "UniProt", "db_id": "Q09YH0" }, { "db_name": "UniProt", "db_id": "Q09YJ4" }, { "db_name": "UniProt", "db_id": "Q09YK5" }, { "db_name": "UniProt", "db_id": "Q108U0" }, { "db_name": "UniProt", "db_id": "Q2IBA1" }, { "db_name": "UniProt", "db_id": "Q2IBB3" }, { "db_name": "UniProt", "db_id": "Q2IBE4" }, { "db_name": "UniProt", "db_id": "Q2IBF6" }, { "db_name": "UniProt", "db_id": "Q2QL74" }, { "db_name": "UniProt", "db_id": "Q2QL83" }, { "db_name": "UniProt", "db_id": "Q2QLA3" }, { "db_name": "UniProt", "db_id": "Q2QLB4" }, { "db_name": "UniProt", "db_id": "Q2QLC5" }, { "db_name": "UniProt", "db_id": "Q2QLE5" }, { "db_name": "UniProt", "db_id": "Q2QLF9" }, { "db_name": "UniProt", "db_id": "Q2QLH0" }, { "db_name": "UniProt", "db_id": "Q5D1Z7" }, { "db_name": "UniProt", "db_id": "Q5U820" }, { "db_name": "UniProt", "db_id": "Q6PQZ2" }, { "db_name": "UniProt", "db_id": "Q7JII7" }, { "db_name": "UniProt", "db_id": "Q7JII8" }, { "db_name": "UniProt", "db_id": "Q9TSP5" }, { "db_name": "UniProt", "db_id": "Q9TUQ2" } ] }, { "id": "DS.d888.s0.e3", "type": "compound", "text": [ "cAMP" ], "offsets": [ [ 222, 226 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6076" } ] }, { "id": "DS.d888.s0.e4", "type": "compound", "text": [ "Cl" ], "offsets": [ [ 237, 239 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "312" } ] }, { "id": "DS.d888.s0.e5", "type": "compound", "text": [ "Na" ], "offsets": [ [ 270, 272 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "923" }, { "db_name": "PubChem", "db_id": "373840" } ] } ]
[]
[]
[ { "id": "DS.d888.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e5", "arg2_id": "DS.d888.s0.e1", "normalized": [] }, { "id": "DS.d888.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e3", "arg2_id": "DS.d888.s0.e1", "normalized": [] }, { "id": "DS.d888.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e5", "arg2_id": "DS.d888.s0.e0", "normalized": [] }, { "id": "DS.d888.s0.i3", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e3", "arg2_id": "DS.d888.s0.e0", "normalized": [] }, { "id": "DS.d888.s0.i4", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e4", "arg2_id": "DS.d888.s0.e1", "normalized": [] }, { "id": "DS.d888.s0.i5", "type": "compound-protein-interaction", "arg1_id": "DS.d888.s0.e4", "arg2_id": "DS.d888.s0.e0", "normalized": [] } ]
DS.d889
18723471
[ { "id": "DS.d889.s0", "type": "", "text": [ "Two patients presented a heterozygous T-to-G transversion in exon 2 (c.518T>G) of the PROKR2, which results in a leucine-to-arginine substitution at codon 173." ], "offsets": [ [ 0, 162 ] ] } ]
[ { "id": "DS.d889.s0.e0", "type": "protein", "text": [ "PROKR2" ], "offsets": [ [ 89, 95 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q8NFJ6" }, { "db_name": "UniProt", "db_id": "Q8SPN1" } ] }, { "id": "DS.d889.s0.e1", "type": "compound", "text": [ "leucine" ], "offsets": [ [ 116, 123 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "857" }, { "db_name": "PubChem", "db_id": "6106" }, { "db_name": "PubChem", "db_id": "439524" } ] }, { "id": "DS.d889.s0.e2", "type": "compound", "text": [ "arginine" ], "offsets": [ [ 127, 135 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "232" }, { "db_name": "PubChem", "db_id": "4367" }, { "db_name": "PubChem", "db_id": "6322" } ] } ]
[]
[]
[ { "id": "DS.d889.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d889.s0.e2", "arg2_id": "DS.d889.s0.e0", "normalized": [] }, { "id": "DS.d889.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d889.s0.e1", "arg2_id": "DS.d889.s0.e0", "normalized": [] } ]
DS.d890
18723570
[ { "id": "DS.d890.s0", "type": "", "text": [ "Mycophenolic acid inhibits the autocrine PDGF-B synthesis and PDGF-BB-induced mRNA expression of Egr-1 in rat mesangial cells." ], "offsets": [ [ 0, 126 ] ] } ]
[ { "id": "DS.d890.s0.e0", "type": "compound", "text": [ "Mycophenolic acid" ], "offsets": [ [ 0, 17 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "446541" } ] }, { "id": "DS.d890.s0.e1", "type": "protein", "text": [ "Egr-1" ], "offsets": [ [ 97, 102 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P08046" } ] } ]
[]
[]
[ { "id": "DS.d890.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d890.s0.e0", "arg2_id": "DS.d890.s0.e1", "normalized": [] } ]
DS.d891
18723579
[ { "id": "DS.d891.s0", "type": "", "text": [ "Angiotensin II (AngII) stimulation of water and NaCl intake is a classic model of the behavioural effects of hormones." ], "offsets": [ [ 0, 118 ] ] }, { "id": "DS.d891.s1", "type": "", "text": [ "Previous studies support the hypotheses that PKC is involved in AngII-induced water, but not NaCl intake and that MAP kinase plays a role in NaCl consumption, but not water intake, after injection of AngII." ], "offsets": [ [ 119, 325 ] ] }, { "id": "DS.d891.s2", "type": "", "text": [ "Pretreatment with the PKC inhibitor chelerythrine attenuated AngII-induced water intake, but NaCl intake was unaffected." ], "offsets": [ [ 326, 446 ] ] }, { "id": "DS.d891.s3", "type": "", "text": [ "In contrast, pretreatment with U0126, a MAP kinase inhibitor, had no effect on AngII-induced water intake, but attenuated NaCl intake." ], "offsets": [ [ 447, 581 ] ] } ]
[ { "id": "DS.d891.s0.e0", "type": "protein", "text": [ "Angiotensin II" ], "offsets": [ [ 0, 14 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01015" }, { "db_name": "UniProt", "db_id": "P01016" }, { "db_name": "UniProt", "db_id": "P01017" }, { "db_name": "UniProt", "db_id": "P01019" }, { "db_name": "UniProt", "db_id": "P11859" }, { "db_name": "UniProt", "db_id": "P20757" }, { "db_name": "UniProt", "db_id": "P67885" }, { "db_name": "UniProt", "db_id": "P67886" }, { "db_name": "UniProt", "db_id": "Q9GLN8" }, { "db_name": "UniProt", "db_id": "Q9GLP6" }, { "db_name": "UniProt", "db_id": "Q9TSZ0" } ] }, { "id": "DS.d891.s0.e1", "type": "protein", "text": [ "AngII" ], "offsets": [ [ 16, 21 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01015" }, { "db_name": "UniProt", "db_id": "P01016" }, { "db_name": "UniProt", "db_id": "P01017" }, { "db_name": "UniProt", "db_id": "P01019" }, { "db_name": "UniProt", "db_id": "P11859" }, { "db_name": "UniProt", "db_id": "P20757" }, { "db_name": "UniProt", "db_id": "P67885" }, { "db_name": "UniProt", "db_id": "P67886" }, { "db_name": "UniProt", "db_id": "Q9GLN8" }, { "db_name": "UniProt", "db_id": "Q9GLP6" }, { "db_name": "UniProt", "db_id": "Q9TSZ0" } ] }, { "id": "DS.d891.s0.e2", "type": "compound", "text": [ "NaCl" ], "offsets": [ [ 48, 52 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5234" } ] }, { "id": "DS.d891.s1.e0", "type": "protein", "text": [ "PKC" ], "offsets": [ [ 164, 167 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P05130" }, { "db_name": "UniProt", "db_id": "P13677" }, { "db_name": "UniProt", "db_id": "P13678" }, { "db_name": "UniProt", "db_id": "P34722" } ] }, { "id": "DS.d891.s1.e1", "type": "compound", "text": [ "NaCl" ], "offsets": [ [ 212, 216 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5234" } ] }, { "id": "DS.d891.s1.e2", "type": "compound", "text": [ "NaCl" ], "offsets": [ [ 260, 264 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5234" } ] }, { "id": "DS.d891.s2.e0", "type": "compound", "text": [ "chelerythrine" ], "offsets": [ [ 362, 375 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2703" }, { "db_name": "PubChem", "db_id": "411938" } ] }, { "id": "DS.d891.s2.e1", "type": "protein", "text": [ "AngII" ], "offsets": [ [ 387, 392 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01015" }, { "db_name": "UniProt", "db_id": "P01016" }, { "db_name": "UniProt", "db_id": "P01017" }, { "db_name": "UniProt", "db_id": "P01019" }, { "db_name": "UniProt", "db_id": "P11859" }, { "db_name": "UniProt", "db_id": "P20757" }, { "db_name": "UniProt", "db_id": "P67885" }, { "db_name": "UniProt", "db_id": "P67886" }, { "db_name": "UniProt", "db_id": "Q9GLN8" }, { "db_name": "UniProt", "db_id": "Q9GLP6" }, { "db_name": "UniProt", "db_id": "Q9TSZ0" } ] }, { "id": "DS.d891.s2.e2", "type": "compound", "text": [ "NaCl" ], "offsets": [ [ 419, 423 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5234" } ] }, { "id": "DS.d891.s3.e0", "type": "protein", "text": [ "AngII" ], "offsets": [ [ 526, 531 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01015" }, { "db_name": "UniProt", "db_id": "P01016" }, { "db_name": "UniProt", "db_id": "P01017" }, { "db_name": "UniProt", "db_id": "P01019" }, { "db_name": "UniProt", "db_id": "P11859" }, { "db_name": "UniProt", "db_id": "P20757" }, { "db_name": "UniProt", "db_id": "P67885" }, { "db_name": "UniProt", "db_id": "P67886" }, { "db_name": "UniProt", "db_id": "Q9GLN8" }, { "db_name": "UniProt", "db_id": "Q9GLP6" }, { "db_name": "UniProt", "db_id": "Q9TSZ0" } ] }, { "id": "DS.d891.s3.e1", "type": "compound", "text": [ "NaCl" ], "offsets": [ [ 569, 573 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5234" } ] } ]
[]
[]
[ { "id": "DS.d891.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d891.s0.e2", "arg2_id": "DS.d891.s0.e1", "normalized": [] }, { "id": "DS.d891.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d891.s0.e2", "arg2_id": "DS.d891.s0.e0", "normalized": [] }, { "id": "DS.d891.s2.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d891.s2.e0", "arg2_id": "DS.d891.s2.e1", "normalized": [] } ]
DS.d893
18724397
[ { "id": "DS.d893.s0", "type": "", "text": [ "The prevalence rates of elevated blood pressure and hypertriglyceridemia were significantly higher among HCT recipients than among controls, but the prevalence rates of abdominal obesity, elevated blood glucose and low high-density lipoprotein cholesterol were not." ], "offsets": [ [ 0, 265 ] ] } ]
[ { "id": "DS.d893.s0.e0", "type": "compound", "text": [ "glucose" ], "offsets": [ [ 203, 210 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "206" }, { "db_name": "PubChem", "db_id": "5793" }, { "db_name": "PubChem", "db_id": "64689" }, { "db_name": "PubChem", "db_id": "79025" } ] }, { "id": "DS.d893.s0.e1", "type": "protein", "text": [ "high-density lipoprotein" ], "offsets": [ [ 219, 243 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P81182" } ] }, { "id": "DS.d893.s0.e2", "type": "compound", "text": [ "cholesterol" ], "offsets": [ [ 244, 255 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "304" }, { "db_name": "PubChem", "db_id": "5997" }, { "db_name": "PubChem", "db_id": "6432564" }, { "db_name": "PubChem", "db_id": "11025495" } ] } ]
[]
[]
[ { "id": "DS.d893.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d893.s0.e2", "arg2_id": "DS.d893.s0.e1", "normalized": [] } ]
DS.d894
18725236
[ { "id": "DS.d894.s0", "type": "", "text": [ "Specific neurochemical elements in these structures include not only decreases in reward neurotransmission, such as decreases in dopamine and opioid peptide function in the ventral striatum, but also recruitment of brain stress systems, such as corticotropin-releasing factor (CRF), in the extended amygdala." ], "offsets": [ [ 0, 308 ] ] } ]
[ { "id": "DS.d894.s0.e0", "type": "compound", "text": [ "dopamine" ], "offsets": [ [ 129, 137 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "681" } ] }, { "id": "DS.d894.s0.e1", "type": "protein", "text": [ "corticotropin-releasing factor" ], "offsets": [ [ 245, 275 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01142" }, { "db_name": "UniProt", "db_id": "P01143" }, { "db_name": "UniProt", "db_id": "P06296" }, { "db_name": "UniProt", "db_id": "P06850" }, { "db_name": "UniProt", "db_id": "P49188" }, { "db_name": "UniProt", "db_id": "P49926" }, { "db_name": "UniProt", "db_id": "Q8CIT0" }, { "db_name": "UniProt", "db_id": "Q95MI6" }, { "db_name": "UniProt", "db_id": "Q9PTS1" } ] }, { "id": "DS.d894.s0.e2", "type": "protein", "text": [ "CRF" ], "offsets": [ [ 277, 280 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O75973" }, { "db_name": "UniProt", "db_id": "P01142" }, { "db_name": "UniProt", "db_id": "P01143" }, { "db_name": "UniProt", "db_id": "P06296" }, { "db_name": "UniProt", "db_id": "P06850" }, { "db_name": "UniProt", "db_id": "P49188" }, { "db_name": "UniProt", "db_id": "P49926" }, { "db_name": "UniProt", "db_id": "Q8CIT0" }, { "db_name": "UniProt", "db_id": "Q95MI6" }, { "db_name": "UniProt", "db_id": "Q9PTS1" } ] } ]
[]
[]
[ { "id": "DS.d894.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d894.s0.e0", "arg2_id": "DS.d894.s0.e2", "normalized": [] }, { "id": "DS.d894.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d894.s0.e0", "arg2_id": "DS.d894.s0.e1", "normalized": [] } ]
DS.d895
18726068
[ { "id": "DS.d895.s0", "type": "", "text": [ "Neither enzymatic activity of transaminases (AST and ALT) nor urea levels were significantly altered." ], "offsets": [ [ 0, 101 ] ] } ]
[ { "id": "DS.d895.s0.e0", "type": "protein", "text": [ "AST" ], "offsets": [ [ 45, 48 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P0AE37" }, { "db_name": "UniProt", "db_id": "P0AE38" }, { "db_name": "UniProt", "db_id": "P80357" }, { "db_name": "UniProt", "db_id": "P80358" }, { "db_name": "UniProt", "db_id": "Q0TH83" }, { "db_name": "UniProt", "db_id": "Q1C8B0" }, { "db_name": "UniProt", "db_id": "Q1RB46" }, { "db_name": "UniProt", "db_id": "Q321N9" }, { "db_name": "UniProt", "db_id": "Q32G89" }, { "db_name": "UniProt", "db_id": "Q3Z294" }, { "db_name": "UniProt", "db_id": "Q5PHB9" }, { "db_name": "UniProt", "db_id": "Q66B20" }, { "db_name": "UniProt", "db_id": "Q7N2G8" }, { "db_name": "UniProt", "db_id": "Q83L52" }, { "db_name": "UniProt", "db_id": "Q8FH00" }, { "db_name": "UniProt", "db_id": "Q8Z6G0" }, { "db_name": "UniProt", "db_id": "Q8ZPV1" }, { "db_name": "UniProt", "db_id": "Q9NRA2" }, { "db_name": "UniProt", "db_id": "Q9ZC67" } ] }, { "id": "DS.d895.s0.e1", "type": "compound", "text": [ "urea" ], "offsets": [ [ 62, 66 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1176" }, { "db_name": "PubChem", "db_id": "265993" } ] } ]
[]
[]
[]
DS.d896
18726117
[ { "id": "DS.d896.s0", "type": "", "text": [ "On other hand, EGFR gene mutations at kinase domain in non-small cell lung cancer (NSCLC) have been examined for their ability to predict sensitivity to gefitinib or erlotinib." ], "offsets": [ [ 0, 176 ] ] } ]
[ { "id": "DS.d896.s0.e0", "type": "protein", "text": [ "EGFR" ], "offsets": [ [ 15, 19 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P00533" }, { "db_name": "UniProt", "db_id": "P13387" }, { "db_name": "UniProt", "db_id": "P55245" } ] }, { "id": "DS.d896.s0.e1", "type": "compound", "text": [ "gefitinib" ], "offsets": [ [ 153, 162 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "123631" } ] }, { "id": "DS.d896.s0.e2", "type": "compound", "text": [ "erlotinib" ], "offsets": [ [ 166, 175 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "176870" } ] } ]
[]
[]
[ { "id": "DS.d896.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d896.s0.e1", "arg2_id": "DS.d896.s0.e0", "normalized": [] }, { "id": "DS.d896.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d896.s0.e2", "arg2_id": "DS.d896.s0.e0", "normalized": [] } ]
DS.d897
18726675
[ { "id": "DS.d897.s0", "type": "", "text": [ "Although the TO2 hamster heart exhibits normal function at 1 month of age (presymptomatic stage), elevated levels of myeloperoxidase, monocyte chemotactic protein-1, malondialdehyde, osteopontin, and alkaline phosphatase were evident, indicating the presence of inflammation, oxidative stress, and osteogenic phenotype." ], "offsets": [ [ 0, 319 ] ] } ]
[ { "id": "DS.d897.s0.e0", "type": "protein", "text": [ "monocyte chemotactic protein-1" ], "offsets": [ [ 134, 164 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P10148" }, { "db_name": "UniProt", "db_id": "P13500" }, { "db_name": "UniProt", "db_id": "P14844" }, { "db_name": "UniProt", "db_id": "P28292" }, { "db_name": "UniProt", "db_id": "P42831" }, { "db_name": "UniProt", "db_id": "P52203" }, { "db_name": "UniProt", "db_id": "P61274" }, { "db_name": "UniProt", "db_id": "P61275" }, { "db_name": "UniProt", "db_id": "Q08782" }, { "db_name": "UniProt", "db_id": "Q9TTQ3" } ] }, { "id": "DS.d897.s0.e1", "type": "compound", "text": [ "malondialdehyde" ], "offsets": [ [ 166, 181 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "10964" } ] }, { "id": "DS.d897.s0.e2", "type": "protein", "text": [ "alkaline phosphatase" ], "offsets": [ [ 200, 220 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O60109" }, { "db_name": "UniProt", "db_id": "P81800" }, { "db_name": "UniProt", "db_id": "P83456" } ] } ]
[]
[]
[]
DS.d898
18726677
[ { "id": "DS.d898.s0", "type": "", "text": [ "Transitions in the tryptophan microenvironment and secondary structure of two monocot lectins from Sauromatum guttatum and Arisaema tortuosum under different denaturing conditions were studied by steady state and time resolved fluorescence and CD spectroscopy." ], "offsets": [ [ 0, 260 ] ] }, { "id": "DS.d898.s1", "type": "", "text": [ "The lectins exist as tetramers with a single tryptophan residue estimated per monomer, present in a polar environment." ], "offsets": [ [ 261, 379 ] ] }, { "id": "DS.d898.s2", "type": "", "text": [ "Similarly, both the lectins showed a drastic loss of secondary structure in 5 M Gdn-HCl or 6 M Urea or at pH 2.0 and below." ], "offsets": [ [ 380, 503 ] ] } ]
[ { "id": "DS.d898.s0.e0", "type": "compound", "text": [ "tryptophan" ], "offsets": [ [ 19, 29 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1148" }, { "db_name": "PubChem", "db_id": "6305" }, { "db_name": "PubChem", "db_id": "9060" }, { "db_name": "PubChem", "db_id": "5460840" } ] }, { "id": "DS.d898.s0.e1", "type": "protein", "text": [ "lectins" ], "offsets": [ [ 86, 93 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02871" }, { "db_name": "UniProt", "db_id": "P02873" }, { "db_name": "UniProt", "db_id": "P02874" }, { "db_name": "UniProt", "db_id": "P02875" }, { "db_name": "UniProt", "db_id": "P07386" }, { "db_name": "UniProt", "db_id": "P16108" }, { "db_name": "UniProt", "db_id": "P16349" }, { "db_name": "UniProt", "db_id": "P16351" }, { "db_name": "UniProt", "db_id": "P16352" }, { "db_name": "UniProt", "db_id": "P33888" }, { "db_name": "UniProt", "db_id": "P38662" }, { "db_name": "UniProt", "db_id": "P42088" }, { "db_name": "UniProt", "db_id": "P83410" }, { "db_name": "UniProt", "db_id": "P83511" }, { "db_name": "UniProt", "db_id": "P84987" }, { "db_name": "UniProt", "db_id": "Q41114" } ] }, { "id": "DS.d898.s1.e0", "type": "protein", "text": [ "lectins" ], "offsets": [ [ 265, 272 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02871" }, { "db_name": "UniProt", "db_id": "P02873" }, { "db_name": "UniProt", "db_id": "P02874" }, { "db_name": "UniProt", "db_id": "P02875" }, { "db_name": "UniProt", "db_id": "P07386" }, { "db_name": "UniProt", "db_id": "P16108" }, { "db_name": "UniProt", "db_id": "P16349" }, { "db_name": "UniProt", "db_id": "P16351" }, { "db_name": "UniProt", "db_id": "P16352" }, { "db_name": "UniProt", "db_id": "P33888" }, { "db_name": "UniProt", "db_id": "P38662" }, { "db_name": "UniProt", "db_id": "P42088" }, { "db_name": "UniProt", "db_id": "P83410" }, { "db_name": "UniProt", "db_id": "P83511" }, { "db_name": "UniProt", "db_id": "P84987" }, { "db_name": "UniProt", "db_id": "Q41114" } ] }, { "id": "DS.d898.s1.e1", "type": "compound", "text": [ "tryptophan" ], "offsets": [ [ 306, 316 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1148" }, { "db_name": "PubChem", "db_id": "6305" }, { "db_name": "PubChem", "db_id": "9060" }, { "db_name": "PubChem", "db_id": "5460840" } ] }, { "id": "DS.d898.s2.e0", "type": "protein", "text": [ "lectins" ], "offsets": [ [ 400, 407 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02871" }, { "db_name": "UniProt", "db_id": "P02873" }, { "db_name": "UniProt", "db_id": "P02874" }, { "db_name": "UniProt", "db_id": "P02875" }, { "db_name": "UniProt", "db_id": "P07386" }, { "db_name": "UniProt", "db_id": "P16108" }, { "db_name": "UniProt", "db_id": "P16349" }, { "db_name": "UniProt", "db_id": "P16351" }, { "db_name": "UniProt", "db_id": "P16352" }, { "db_name": "UniProt", "db_id": "P33888" }, { "db_name": "UniProt", "db_id": "P38662" }, { "db_name": "UniProt", "db_id": "P42088" }, { "db_name": "UniProt", "db_id": "P83410" }, { "db_name": "UniProt", "db_id": "P83511" }, { "db_name": "UniProt", "db_id": "P84987" }, { "db_name": "UniProt", "db_id": "Q41114" } ] }, { "id": "DS.d898.s2.e1", "type": "compound", "text": [ "Gdn" ], "offsets": [ [ 460, 463 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "97535" } ] }, { "id": "DS.d898.s2.e2", "type": "compound", "text": [ "HCl" ], "offsets": [ [ 464, 467 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "313" } ] }, { "id": "DS.d898.s2.e3", "type": "compound", "text": [ "Urea" ], "offsets": [ [ 475, 479 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1176" }, { "db_name": "PubChem", "db_id": "265993" } ] } ]
[]
[]
[ { "id": "DS.d898.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d898.s1.e1", "arg2_id": "DS.d898.s1.e0", "normalized": [] }, { "id": "DS.d898.s2.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d898.s2.e2", "arg2_id": "DS.d898.s2.e0", "normalized": [] }, { "id": "DS.d898.s2.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d898.s2.e3", "arg2_id": "DS.d898.s2.e0", "normalized": [] }, { "id": "DS.d898.s2.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d898.s2.e1", "arg2_id": "DS.d898.s2.e0", "normalized": [] } ]
DS.d899
18726687
[ { "id": "DS.d899.s0", "type": "", "text": [ "In order to determine the possible effects of hemolysate on brain microvascular endothelial cells (BMECs), we examined the effects of hemolysate on the expression of intercellular adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein-1 (MCP-1), generation of reactive oxygen species (ROS), and NF-kappaB activation in rat BMECs." ], "offsets": [ [ 0, 340 ] ] } ]
[ { "id": "DS.d899.s0.e0", "type": "protein", "text": [ "ICAM-1" ], "offsets": [ [ 201, 207 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P05362" }, { "db_name": "UniProt", "db_id": "P13597" }, { "db_name": "UniProt", "db_id": "P33729" }, { "db_name": "UniProt", "db_id": "Q00238" }, { "db_name": "UniProt", "db_id": "Q28806" }, { "db_name": "UniProt", "db_id": "Q5NKV4" }, { "db_name": "UniProt", "db_id": "Q5NKV6" }, { "db_name": "UniProt", "db_id": "Q5NKV9" }, { "db_name": "UniProt", "db_id": "Q95132" } ] }, { "id": "DS.d899.s0.e1", "type": "protein", "text": [ "monocyte chemoattractant protein-1" ], "offsets": [ [ 213, 247 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P10148" }, { "db_name": "UniProt", "db_id": "P13500" }, { "db_name": "UniProt", "db_id": "P14844" }, { "db_name": "UniProt", "db_id": "P28292" }, { "db_name": "UniProt", "db_id": "P42831" }, { "db_name": "UniProt", "db_id": "P52203" }, { "db_name": "UniProt", "db_id": "P61274" }, { "db_name": "UniProt", "db_id": "P61275" }, { "db_name": "UniProt", "db_id": "Q08782" }, { "db_name": "UniProt", "db_id": "Q9TTQ3" } ] }, { "id": "DS.d899.s0.e2", "type": "protein", "text": [ "MCP-1" ], "offsets": [ [ 249, 254 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P10148" }, { "db_name": "UniProt", "db_id": "P13500" }, { "db_name": "UniProt", "db_id": "P14844" }, { "db_name": "UniProt", "db_id": "P28291" }, { "db_name": "UniProt", "db_id": "P28292" }, { "db_name": "UniProt", "db_id": "P42831" }, { "db_name": "UniProt", "db_id": "P52203" }, { "db_name": "UniProt", "db_id": "P61274" }, { "db_name": "UniProt", "db_id": "P61275" }, { "db_name": "UniProt", "db_id": "Q08782" }, { "db_name": "UniProt", "db_id": "Q9TTQ3" } ] }, { "id": "DS.d899.s0.e3", "type": "compound", "text": [ "oxygen" ], "offsets": [ [ 280, 286 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "977" } ] } ]
[]
[]
[]
DS.d900
18726998
[ { "id": "DS.d900.s0", "type": "", "text": [ "We examined 1,25 dihydroxyvitamin D (1,25(OH)(2)D(3))-induced expression of 25-hydroxyvitamin D(3) 24-hydroxylase (CYP24) and apical calcium channel (TRPV6) mRNA levels in 2-, 9-, and 15-day cultures Caco-2 cells that model proliferating, post-proliferative, and differentiated enterocytes." ], "offsets": [ [ 0, 290 ] ] } ]
[ { "id": "DS.d900.s0.e0", "type": "compound", "text": [ "1,25 dihydroxyvitamin D" ], "offsets": [ [ 12, 35 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5280453" } ] }, { "id": "DS.d900.s0.e1", "type": "protein", "text": [ "CYP24" ], "offsets": [ [ 115, 120 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q07973" } ] }, { "id": "DS.d900.s0.e2", "type": "protein", "text": [ "TRPV6" ], "offsets": [ [ 150, 155 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q9H1D0" } ] } ]
[]
[]
[ { "id": "DS.d900.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d900.s0.e0", "arg2_id": "DS.d900.s0.e2", "normalized": [] }, { "id": "DS.d900.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d900.s0.e0", "arg2_id": "DS.d900.s0.e1", "normalized": [] } ]
DS.d901
18727009
[ { "id": "DS.d901.s0", "type": "", "text": [ "Here, we tested the hypothesis that interactions with DNA-topoisomerases play a role in the DNA-damaging properties of AOH." ], "offsets": [ [ 0, 123 ] ] }, { "id": "DS.d901.s1", "type": "", "text": [ "Next, we selected AOH as the most DNA-damaging Alternaria metabolite for further studies of interactions with DNA topoisomerases." ], "offsets": [ [ 124, 253 ] ] }, { "id": "DS.d901.s2", "type": "", "text": [ "Stabilisation of covalent topoisomerase II-DNA intermediates by AOH was also detectable in cell culture, and here, the IIalpha isoform was preferentially targeted." ], "offsets": [ [ 254, 417 ] ] } ]
[ { "id": "DS.d901.s0.e0", "type": "protein", "text": [ "DNA-topoisomerases" ], "offsets": [ [ 54, 72 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P38086" } ] }, { "id": "DS.d901.s0.e1", "type": "compound", "text": [ "AOH" ], "offsets": [ [ 119, 122 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5359485" } ] }, { "id": "DS.d901.s1.e0", "type": "compound", "text": [ "AOH" ], "offsets": [ [ 142, 145 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5359485" } ] }, { "id": "DS.d901.s1.e1", "type": "protein", "text": [ "DNA topoisomerases" ], "offsets": [ [ 234, 252 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P38086" } ] }, { "id": "DS.d901.s2.e0", "type": "protein", "text": [ "topoisomerase" ], "offsets": [ [ 280, 293 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O29238" }, { "db_name": "UniProt", "db_id": "O51934" }, { "db_name": "UniProt", "db_id": "O58530" }, { "db_name": "UniProt", "db_id": "O67037" }, { "db_name": "UniProt", "db_id": "O67226" }, { "db_name": "UniProt", "db_id": "P74759" }, { "db_name": "UniProt", "db_id": "P95479" }, { "db_name": "UniProt", "db_id": "Q08582" }, { "db_name": "UniProt", "db_id": "Q58907" }, { "db_name": "UniProt", "db_id": "Q6F598" }, { "db_name": "UniProt", "db_id": "Q8R979" }, { "db_name": "UniProt", "db_id": "Q8ZXT5" }, { "db_name": "UniProt", "db_id": "Q971T7" }, { "db_name": "UniProt", "db_id": "Q975P6" }, { "db_name": "UniProt", "db_id": "Q97ZF5" }, { "db_name": "UniProt", "db_id": "Q97ZZ8" }, { "db_name": "UniProt", "db_id": "Q9UZ86" }, { "db_name": "UniProt", "db_id": "Q9YC75" }, { "db_name": "UniProt", "db_id": "Q9YCB6" } ] }, { "id": "DS.d901.s2.e1", "type": "compound", "text": [ "AOH" ], "offsets": [ [ 318, 321 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5359485" } ] } ]
[]
[]
[ { "id": "DS.d901.s2.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d901.s2.e1", "arg2_id": "DS.d901.s2.e0", "normalized": [] } ]
DS.d902
18727113
[ { "id": "DS.d902.s0", "type": "", "text": [ "Bone formation and maturation processes were evaluated by double staining for alkaline phosphatase and tartrate-resistant acid phosphatase, immunohistochemistry for bone matrix proteins, vital staining with calcein, and elemental mapping with an electron probe microanalyzer." ], "offsets": [ [ 0, 275 ] ] } ]
[ { "id": "DS.d902.s0.e0", "type": "protein", "text": [ "alkaline phosphatase" ], "offsets": [ [ 78, 98 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O60109" }, { "db_name": "UniProt", "db_id": "P81800" }, { "db_name": "UniProt", "db_id": "P83456" } ] }, { "id": "DS.d902.s0.e1", "type": "protein", "text": [ "phosphatase" ], "offsets": [ [ 87, 98 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P06961" }, { "db_name": "UniProt", "db_id": "P45269" }, { "db_name": "UniProt", "db_id": "Q57JQ5" }, { "db_name": "UniProt", "db_id": "Q5E2K7" }, { "db_name": "UniProt", "db_id": "Q5F8K9" }, { "db_name": "UniProt", "db_id": "Q5P3T0" }, { "db_name": "UniProt", "db_id": "Q5PC82" }, { "db_name": "UniProt", "db_id": "Q5WT58" }, { "db_name": "UniProt", "db_id": "Q5X1E5" }, { "db_name": "UniProt", "db_id": "Q5ZRX9" }, { "db_name": "UniProt", "db_id": "Q60CQ4" }, { "db_name": "UniProt", "db_id": "Q62EU1" }, { "db_name": "UniProt", "db_id": "Q63YC3" }, { "db_name": "UniProt", "db_id": "Q65Q41" }, { "db_name": "UniProt", "db_id": "Q665U9" }, { "db_name": "UniProt", "db_id": "Q6D160" }, { "db_name": "UniProt", "db_id": "Q6FA38" }, { "db_name": "UniProt", "db_id": "Q6LV05" }, { "db_name": "UniProt", "db_id": "Q7M7K5" }, { "db_name": "UniProt", "db_id": "Q7MAZ9" }, { "db_name": "UniProt", "db_id": "Q7MBF4" }, { "db_name": "UniProt", "db_id": "Q821A6" }, { "db_name": "UniProt", "db_id": "Q82U82" }, { "db_name": "UniProt", "db_id": "Q87DS9" }, { "db_name": "UniProt", "db_id": "Q87SK9" }, { "db_name": "UniProt", "db_id": "Q88A53" }, { "db_name": "UniProt", "db_id": "Q88QU2" }, { "db_name": "UniProt", "db_id": "Q8CWL6" }, { "db_name": "UniProt", "db_id": "Q8CXX6" }, { "db_name": "UniProt", "db_id": "Q8P5D4" }, { "db_name": "UniProt", "db_id": "Q8PPG9" }, { "db_name": "UniProt", "db_id": "Q8XBL4" }, { "db_name": "UniProt", "db_id": "Q8Y395" }, { "db_name": "UniProt", "db_id": "Q8Z3M9" }, { "db_name": "UniProt", "db_id": "Q8ZI64" }, { "db_name": "UniProt", "db_id": "Q8ZLY4" }, { "db_name": "UniProt", "db_id": "Q9CP21" }, { "db_name": "UniProt", "db_id": "Q9I5V3" }, { "db_name": "UniProt", "db_id": "Q9JUB2" }, { "db_name": "UniProt", "db_id": "Q9JZ88" }, { "db_name": "UniProt", "db_id": "Q9KPC6" }, { "db_name": "UniProt", "db_id": "Q9L7A3" }, { "db_name": "UniProt", "db_id": "Q9PDL7" } ] }, { "id": "DS.d902.s0.e2", "type": "protein", "text": [ "matrix proteins" ], "offsets": [ [ 170, 185 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12705" }, { "db_name": "UniProt", "db_id": "O18559" }, { "db_name": "UniProt", "db_id": "O57299" }, { "db_name": "UniProt", "db_id": "O89341" }, { "db_name": "UniProt", "db_id": "P03314" }, { "db_name": "UniProt", "db_id": "P03344" }, { "db_name": "UniProt", "db_id": "P03419" }, { "db_name": "UniProt", "db_id": "P03426" }, { "db_name": "UniProt", "db_id": "P03519" }, { "db_name": "UniProt", "db_id": "P04876" }, { "db_name": "UniProt", "db_id": "P04888" }, { "db_name": "UniProt", "db_id": "P05769" }, { "db_name": "UniProt", "db_id": "P06157" }, { "db_name": "UniProt", "db_id": "P06166" }, { "db_name": "UniProt", "db_id": "P06446" }, { "db_name": "UniProt", "db_id": "P06502" }, { "db_name": "UniProt", "db_id": "P06503" }, { "db_name": "UniProt", "db_id": "P06935" }, { "db_name": "UniProt", "db_id": "P06942" }, { "db_name": "UniProt", "db_id": "P06943" }, { "db_name": "UniProt", "db_id": "P07564" }, { "db_name": "UniProt", "db_id": "P07720" }, { "db_name": "UniProt", "db_id": "P07873" }, { "db_name": "UniProt", "db_id": "P08325" }, { "db_name": "UniProt", "db_id": "P08671" }, { "db_name": "UniProt", "db_id": "P09732" }, { "db_name": "UniProt", "db_id": "P09866" }, { "db_name": "UniProt", "db_id": "P11206" }, { "db_name": "UniProt", "db_id": "P12446" }, { "db_name": "UniProt", "db_id": "P12823" }, { "db_name": "UniProt", "db_id": "P13616" }, { "db_name": "UniProt", "db_id": "P13844" }, { "db_name": "UniProt", "db_id": "P14335" }, { "db_name": "UniProt", "db_id": "P14336" }, { "db_name": "UniProt", "db_id": "P14340" }, { "db_name": "UniProt", "db_id": "P14403" }, { "db_name": "UniProt", "db_id": "P15200" }, { "db_name": "UniProt", "db_id": "P16287" }, { "db_name": "UniProt", "db_id": "P16628" }, { "db_name": "UniProt", "db_id": "P16629" }, { "db_name": "UniProt", "db_id": "P17748" }, { "db_name": "UniProt", "db_id": "P17763" }, { "db_name": "UniProt", "db_id": "P18356" }, { "db_name": "UniProt", "db_id": "P18611" }, { "db_name": "UniProt", "db_id": "P19110" }, { "db_name": "UniProt", "db_id": "P19692" }, { "db_name": "UniProt", "db_id": "P19718" }, { "db_name": "UniProt", "db_id": "P22046" }, { "db_name": "UniProt", "db_id": "P22338" }, { "db_name": "UniProt", "db_id": "P24266" }, { "db_name": "UniProt", "db_id": "P24615" }, { "db_name": "UniProt", "db_id": "P25058" }, { "db_name": "UniProt", "db_id": "P25182" }, { "db_name": "UniProt", "db_id": "P25223" }, { "db_name": "UniProt", "db_id": "P25224" }, { "db_name": "UniProt", "db_id": "P26034" }, { "db_name": "UniProt", "db_id": "P27019" }, { "db_name": "UniProt", "db_id": "P27020" }, { "db_name": "UniProt", "db_id": "P27287" }, { "db_name": "UniProt", "db_id": "P27395" }, { "db_name": "UniProt", "db_id": "P27663" }, { "db_name": "UniProt", "db_id": "P27910" }, { "db_name": "UniProt", "db_id": "P27912" }, { "db_name": "UniProt", "db_id": "P27913" }, { "db_name": "UniProt", "db_id": "P27915" }, { "db_name": "UniProt", "db_id": "P29165" }, { "db_name": "UniProt", "db_id": "P29837" }, { "db_name": "UniProt", "db_id": "P29838" }, { "db_name": "UniProt", "db_id": "P29983" }, { "db_name": "UniProt", "db_id": "P29984" }, { "db_name": "UniProt", "db_id": "P29990" }, { "db_name": "UniProt", "db_id": "P29991" }, { "db_name": "UniProt", "db_id": "P30026" }, { "db_name": "UniProt", "db_id": "P31035" }, { "db_name": "UniProt", "db_id": "P31620" }, { "db_name": "UniProt", "db_id": "P32886" }, { "db_name": "UniProt", "db_id": "P33478" }, { "db_name": "UniProt", "db_id": "P33482" }, { "db_name": "UniProt", "db_id": "P33515" }, { "db_name": "UniProt", "db_id": "P35947" }, { "db_name": "UniProt", "db_id": "P35976" }, { "db_name": "UniProt", "db_id": "P36355" }, { "db_name": "UniProt", "db_id": "P36356" }, { "db_name": "UniProt", "db_id": "P41358" }, { "db_name": "UniProt", "db_id": "P52637" }, { "db_name": "UniProt", "db_id": "P62683" }, { "db_name": "UniProt", "db_id": "P62684" }, { "db_name": "UniProt", "db_id": "P62685" }, { "db_name": "UniProt", "db_id": "P62689" }, { "db_name": "UniProt", "db_id": "P62690" }, { "db_name": "UniProt", "db_id": "P63117" }, { "db_name": "UniProt", "db_id": "P63126" }, { "db_name": "UniProt", "db_id": "P63128" }, { "db_name": "UniProt", "db_id": "P63130" }, { "db_name": "UniProt", "db_id": "P63145" }, { "db_name": "UniProt", "db_id": "P87577" }, { "db_name": "UniProt", "db_id": "P87889" }, { "db_name": "UniProt", "db_id": "Q01299" }, { "db_name": "UniProt", "db_id": "Q01427" }, { "db_name": "UniProt", "db_id": "Q04538" }, { "db_name": "UniProt", "db_id": "Q074N0" }, { "db_name": "UniProt", "db_id": "Q1X880" }, { "db_name": "UniProt", "db_id": "Q1X881" }, { "db_name": "UniProt", "db_id": "Q66112" }, { "db_name": "UniProt", "db_id": "Q6DV88" }, { "db_name": "UniProt", "db_id": "Q6J3P1" }, { "db_name": "UniProt", "db_id": "Q7LDI9" }, { "db_name": "UniProt", "db_id": "Q84131" }, { "db_name": "UniProt", "db_id": "Q88266" }, { "db_name": "UniProt", "db_id": "Q88428" }, { "db_name": "UniProt", "db_id": "Q89277" }, { "db_name": "UniProt", "db_id": "Q91B74" }, { "db_name": "UniProt", "db_id": "Q96PI4" }, { "db_name": "UniProt", "db_id": "Q98803" }, { "db_name": "UniProt", "db_id": "Q9HDB9" }, { "db_name": "UniProt", "db_id": "Q9IK90" }, { "db_name": "UniProt", "db_id": "Q9JAF2" }, { "db_name": "UniProt", "db_id": "Q9NRZ4" }, { "db_name": "UniProt", "db_id": "Q9UKH8" }, { "db_name": "UniProt", "db_id": "Q9YNA8" }, { "db_name": "UniProt", "db_id": "Q9YRV3" } ] }, { "id": "DS.d902.s0.e3", "type": "compound", "text": [ "calcein" ], "offsets": [ [ 207, 214 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "65079" } ] } ]
[]
[]
[]
DS.d903
18728222
[ { "id": "DS.d903.s0", "type": "", "text": [ "Phosphorylation of insulin receptor substrate (IRS) proteins on serine residues has emerged as a key step in these control processes under both physiological and pathological conditions." ], "offsets": [ [ 0, 186 ] ] } ]
[ { "id": "DS.d903.s0.e0", "type": "protein", "text": [ "insulin receptor" ], "offsets": [ [ 19, 35 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q28516" } ] }, { "id": "DS.d903.s0.e1", "type": "protein", "text": [ "IRS" ], "offsets": [ [ 47, 50 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P41252" }, { "db_name": "UniProt", "db_id": "Q8BU30" }, { "db_name": "UniProt", "db_id": "Q9XTN2" } ] }, { "id": "DS.d903.s0.e2", "type": "compound", "text": [ "serine" ], "offsets": [ [ 64, 70 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5951" } ] } ]
[]
[]
[ { "id": "DS.d903.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d903.s0.e2", "arg2_id": "DS.d903.s0.e1", "normalized": [] }, { "id": "DS.d903.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d903.s0.e2", "arg2_id": "DS.d903.s0.e0", "normalized": [] } ]
DS.d904
18728345
[ { "id": "DS.d904.s0", "type": "", "text": [ "In contrast, SKI-1 (S1P or site-1) is a membrane-bound serine protease inhibitable by AEBSF." ], "offsets": [ [ 0, 92 ] ] } ]
[ { "id": "DS.d904.s0.e0", "type": "protein", "text": [ "SKI-1" ], "offsets": [ [ 13, 18 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q14703" }, { "db_name": "UniProt", "db_id": "Q9WTZ2" }, { "db_name": "UniProt", "db_id": "Q9WTZ3" }, { "db_name": "UniProt", "db_id": "Q9Z2A8" } ] }, { "id": "DS.d904.s0.e1", "type": "protein", "text": [ "S1P" ], "offsets": [ [ 20, 23 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q14703" }, { "db_name": "UniProt", "db_id": "Q9Z2A8" } ] }, { "id": "DS.d904.s0.e2", "type": "protein", "text": [ "serine protease" ], "offsets": [ [ 55, 70 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P83290" } ] }, { "id": "DS.d904.s0.e3", "type": "compound", "text": [ "AEBSF" ], "offsets": [ [ 86, 91 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1701" } ] } ]
[]
[]
[ { "id": "DS.d904.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d904.s0.e3", "arg2_id": "DS.d904.s0.e1", "normalized": [] }, { "id": "DS.d904.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d904.s0.e3", "arg2_id": "DS.d904.s0.e0", "normalized": [] }, { "id": "DS.d904.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d904.s0.e3", "arg2_id": "DS.d904.s0.e2", "normalized": [] } ]
DS.d905
18728347
[ { "id": "DS.d905.s0", "type": "", "text": [ "The progressive ankylosis gene (ank) is a transmembrane protein that transports intracellular pyrophosphate to the extracellular milieu." ], "offsets": [ [ 0, 136 ] ] } ]
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[]
[]
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DS.d906
18728678
[ { "id": "DS.d906.s0", "type": "", "text": [ "Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices." ], "offsets": [ [ 0, 170 ] ] }, { "id": "DS.d906.s1", "type": "", "text": [ "The role of tumor necrosis factor (TNF) receptors 1 and 2 in lipopolysaccharide (LPS)-induced sensitization and tolerance to oxygen-glucose deprivation (OGD) was evaluated in neonatal murine hippocampal organotypic slices." ], "offsets": [ [ 171, 393 ] ] } ]
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[]
[]
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DS.d907
18729103
[ { "id": "DS.d907.s0", "type": "", "text": [ "The immunoblot, ELISA and EMSA analysis demonstrated that the treatment of HCT116 cells with delphinidin resulted in the inhibition of (i) IKKalpha, (ii) phosphorylation and degradation of IkappaBalpha, (iii) phosphorylation of NF-kappaB/p65 at Ser (536), (iv) nuclear translocation of NF-kappaB/p65, (v) NF-kappaB/p65 DNA binding activity, and (vi) transcriptional activation of NF-kappaB." ], "offsets": [ [ 0, 390 ] ] } ]
[ { "id": "DS.d907.s0.e0", "type": "compound", "text": [ "delphinidin" ], "offsets": [ [ 93, 104 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "128853" } ] }, { "id": "DS.d907.s0.e1", "type": "protein", "text": [ "IKKalpha" ], "offsets": [ [ 139, 147 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O15111" }, { "db_name": "UniProt", "db_id": "Q60680" } ] }, { "id": "DS.d907.s0.e2", "type": "protein", "text": [ "IkappaBalpha" ], "offsets": [ [ 189, 201 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P25963" }, { "db_name": "UniProt", "db_id": "Q08353" }, { "db_name": "UniProt", "db_id": "Q63746" }, { "db_name": "UniProt", "db_id": "Q91974" }, { "db_name": "UniProt", "db_id": "Q9Z1E3" } ] }, { "id": "DS.d907.s0.e3", "type": "protein", "text": [ "p65" ], "offsets": [ [ 238, 241 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P16342" }, { "db_name": "UniProt", "db_id": "P19751" }, { "db_name": "UniProt", "db_id": "P21521" }, { "db_name": "UniProt", "db_id": "P21579" }, { "db_name": "UniProt", "db_id": "P21707" }, { "db_name": "UniProt", "db_id": "P41823" }, { "db_name": "UniProt", "db_id": "P46096" }, { "db_name": "UniProt", "db_id": "P47191" }, { "db_name": "UniProt", "db_id": "P48018" }, { "db_name": "UniProt", "db_id": "P53663" }, { "db_name": "UniProt", "db_id": "P54963" }, { "db_name": "UniProt", "db_id": "Q42920" }, { "db_name": "UniProt", "db_id": "Q49539" }, { "db_name": "UniProt", "db_id": "Q66198" }, { "db_name": "UniProt", "db_id": "Q8V439" }, { "db_name": "UniProt", "db_id": "Q8V6W7" }, { "db_name": "UniProt", "db_id": "Q91A29" }, { "db_name": "UniProt", "db_id": "Q9FJR1" }, { "db_name": "UniProt", "db_id": "Q9PYA3" } ] }, { "id": "DS.d907.s0.e4", "type": "protein", "text": [ "p65" ], "offsets": [ [ 296, 299 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P16342" }, { "db_name": "UniProt", "db_id": "P19751" }, { "db_name": "UniProt", "db_id": "P21521" }, { "db_name": "UniProt", "db_id": "P21579" }, { "db_name": "UniProt", "db_id": "P21707" }, { "db_name": "UniProt", "db_id": "P41823" }, { "db_name": "UniProt", "db_id": "P46096" }, { "db_name": "UniProt", "db_id": "P47191" }, { "db_name": "UniProt", "db_id": "P48018" }, { "db_name": "UniProt", "db_id": "P53663" }, { "db_name": "UniProt", "db_id": "P54963" }, { "db_name": "UniProt", "db_id": "Q42920" }, { "db_name": "UniProt", "db_id": "Q49539" }, { "db_name": "UniProt", "db_id": "Q66198" }, { "db_name": "UniProt", "db_id": "Q8V439" }, { "db_name": "UniProt", "db_id": "Q8V6W7" }, { "db_name": "UniProt", "db_id": "Q91A29" }, { "db_name": "UniProt", "db_id": "Q9FJR1" }, { "db_name": "UniProt", "db_id": "Q9PYA3" } ] }, { "id": "DS.d907.s0.e5", "type": "protein", "text": [ "p65" ], "offsets": [ [ 296, 299 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P16342" }, { "db_name": "UniProt", "db_id": "P19751" }, { "db_name": "UniProt", "db_id": "P21521" }, { "db_name": "UniProt", "db_id": "P21579" }, { "db_name": "UniProt", "db_id": "P21707" }, { "db_name": "UniProt", "db_id": "P41823" }, { "db_name": "UniProt", "db_id": "P46096" }, { "db_name": "UniProt", "db_id": "P47191" }, { "db_name": "UniProt", "db_id": "P48018" }, { "db_name": "UniProt", "db_id": "P53663" }, { "db_name": "UniProt", "db_id": "P54963" }, { "db_name": "UniProt", "db_id": "Q42920" }, { "db_name": "UniProt", "db_id": "Q49539" }, { "db_name": "UniProt", "db_id": "Q66198" }, { "db_name": "UniProt", "db_id": "Q8V439" }, { "db_name": "UniProt", "db_id": "Q8V6W7" }, { "db_name": "UniProt", "db_id": "Q91A29" }, { "db_name": "UniProt", "db_id": "Q9FJR1" }, { "db_name": "UniProt", "db_id": "Q9PYA3" } ] } ]
[]
[]
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DS.d908
18729824
[ { "id": "DS.d908.s0", "type": "", "text": [ "Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions." ], "offsets": [ [ 0, 114 ] ] }, { "id": "DS.d908.s1", "type": "", "text": [ "The role of the functional architecture of the HuAChE (human acetylcholinesterase) in reactivity toward the carbamates pyridostigmine, rivastigmine and several analogues of physostigmine, that are currently used or considered for use as drugs for Alzheimer's disease, was analysed using over 20 mutants of residues that constitute the interaction subsites in the active centre." ], "offsets": [ [ 115, 492 ] ] } ]
[ { "id": "DS.d908.s0.e0", "type": "compound", "text": [ "physostigmine" ], "offsets": [ [ 17, 30 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5983" }, { "db_name": "PubChem", "db_id": "14107712" } ] }, { "id": "DS.d908.s0.e1", "type": "protein", "text": [ "acetylcholinesterase" ], "offsets": [ [ 52, 72 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q867X2" }, { "db_name": "UniProt", "db_id": "Q867X3" }, { "db_name": "UniProt", "db_id": "Q86GC9" }, { "db_name": "UniProt", "db_id": "Q92081" } ] }, { "id": "DS.d908.s1.e0", "type": "protein", "text": [ "acetylcholinesterase" ], "offsets": [ [ 176, 196 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q867X2" }, { "db_name": "UniProt", "db_id": "Q867X3" }, { "db_name": "UniProt", "db_id": "Q86GC9" }, { "db_name": "UniProt", "db_id": "Q92081" } ] }, { "id": "DS.d908.s1.e1", "type": "compound", "text": [ "pyridostigmine" ], "offsets": [ [ 234, 248 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "4991" } ] }, { "id": "DS.d908.s1.e2", "type": "compound", "text": [ "rivastigmine" ], "offsets": [ [ 250, 262 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "77991" } ] }, { "id": "DS.d908.s1.e3", "type": "compound", "text": [ "physostigmine" ], "offsets": [ [ 288, 301 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5983" }, { "db_name": "PubChem", "db_id": "14107712" } ] } ]
[]
[]
[ { "id": "DS.d908.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d908.s0.e0", "arg2_id": "DS.d908.s0.e1", "normalized": [] }, { "id": "DS.d908.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d908.s1.e2", "arg2_id": "DS.d908.s1.e0", "normalized": [] }, { "id": "DS.d908.s1.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d908.s1.e3", "arg2_id": "DS.d908.s1.e0", "normalized": [] }, { "id": "DS.d908.s1.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d908.s1.e1", "arg2_id": "DS.d908.s1.e0", "normalized": [] } ]
DS.d909
18751681
[ { "id": "DS.d909.s0", "type": "", "text": [ "Cells were grown for 24 h with APAP in the presence or absence of 4-methylpyrazole (4MP), L-arginine methyl ester (L-NAME), superoxide dismutase (SOD), or ruthenium red (RuR)." ], "offsets": [ [ 0, 175 ] ] } ]
[ { "id": "DS.d909.s0.e0", "type": "compound", "text": [ "APAP" ], "offsets": [ [ 31, 35 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1983" } ] }, { "id": "DS.d909.s0.e1", "type": "compound", "text": [ "L-arginine methyl ester" ], "offsets": [ [ 90, 113 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "550788" } ] }, { "id": "DS.d909.s0.e2", "type": "protein", "text": [ "superoxide dismutase" ], "offsets": [ [ 124, 144 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O50258" } ] }, { "id": "DS.d909.s0.e3", "type": "protein", "text": [ "SOD" ], "offsets": [ [ 146, 149 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O12933" }, { "db_name": "UniProt", "db_id": "O22668" }, { "db_name": "UniProt", "db_id": "O75007" }, { "db_name": "UniProt", "db_id": "P24705" }, { "db_name": "UniProt", "db_id": "P51547" }, { "db_name": "UniProt", "db_id": "P93258" }, { "db_name": "UniProt", "db_id": "Q01137" }, { "db_name": "UniProt", "db_id": "Q27666" }, { "db_name": "UniProt", "db_id": "Q9SM64" } ] }, { "id": "DS.d909.s0.e4", "type": "compound", "text": [ "ruthenium" ], "offsets": [ [ 155, 164 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "23950" } ] }, { "id": "DS.d909.s0.e5", "type": "compound", "text": [ "RuR" ], "offsets": [ [ 170, 173 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "4971" } ] } ]
[]
[]
[]
DS.d910
18751889
[ { "id": "DS.d910.s0", "type": "", "text": [ "Synaptic vesicle-bound pyruvate kinase can support vesicular glutamate uptake." ], "offsets": [ [ 0, 78 ] ] }, { "id": "DS.d910.s1", "type": "", "text": [ "We present evidence that ATP generated by synaptic vesicle-associated pyruvate kinase is harnessed to transport glutamate into synaptic vesicles." ], "offsets": [ [ 79, 224 ] ] } ]
[ { "id": "DS.d910.s0.e0", "type": "protein", "text": [ "pyruvate kinase" ], "offsets": [ [ 23, 38 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O05118" }, { "db_name": "UniProt", "db_id": "O06134" }, { "db_name": "UniProt", "db_id": "O08309" }, { "db_name": "UniProt", "db_id": "O44006" }, { "db_name": "UniProt", "db_id": "O51323" }, { "db_name": "UniProt", "db_id": "O62619" }, { "db_name": "UniProt", "db_id": "O94122" }, { "db_name": "UniProt", "db_id": "P19680" }, { "db_name": "UniProt", "db_id": "P22360" }, { "db_name": "UniProt", "db_id": "P30614" }, { "db_name": "UniProt", "db_id": "P31865" }, { "db_name": "UniProt", "db_id": "P32044" }, { "db_name": "UniProt", "db_id": "P34038" }, { "db_name": "UniProt", "db_id": "P43924" }, { "db_name": "UniProt", "db_id": "P46614" }, { "db_name": "UniProt", "db_id": "P47458" }, { "db_name": "UniProt", "db_id": "P51181" }, { "db_name": "UniProt", "db_id": "P51182" }, { "db_name": "UniProt", "db_id": "P57404" }, { "db_name": "UniProt", "db_id": "P70789" }, { "db_name": "UniProt", "db_id": "P78031" }, { "db_name": "UniProt", "db_id": "P80885" }, { "db_name": "UniProt", "db_id": "P81344" }, { "db_name": "UniProt", "db_id": "P94685" }, { "db_name": "UniProt", "db_id": "P94939" }, { "db_name": "UniProt", "db_id": "Q02499" }, { "db_name": "UniProt", "db_id": "Q04668" }, { "db_name": "UniProt", "db_id": "Q07637" }, { "db_name": "UniProt", "db_id": "Q10208" }, { "db_name": "UniProt", "db_id": "Q12669" }, { "db_name": "UniProt", "db_id": "Q27686" }, { "db_name": "UniProt", "db_id": "Q27788" }, { "db_name": "UniProt", "db_id": "Q44473" }, { "db_name": "UniProt", "db_id": "Q46078" }, { "db_name": "UniProt", "db_id": "Q46289" }, { "db_name": "UniProt", "db_id": "Q56301" }, { "db_name": "UniProt", "db_id": "Q57572" }, { "db_name": "UniProt", "db_id": "Q6BS75" }, { "db_name": "UniProt", "db_id": "Q759A9" }, { "db_name": "UniProt", "db_id": "Q7RVA8" }, { "db_name": "UniProt", "db_id": "Q875M9" }, { "db_name": "UniProt", "db_id": "Q875S4" }, { "db_name": "UniProt", "db_id": "Q875Z9" }, { "db_name": "UniProt", "db_id": "Q89AI8" }, { "db_name": "UniProt", "db_id": "Q8FP04" }, { "db_name": "UniProt", "db_id": "Q8K9M3" }, { "db_name": "UniProt", "db_id": "Q9PK61" }, { "db_name": "UniProt", "db_id": "Q9Z984" } ] }, { "id": "DS.d910.s0.e1", "type": "compound", "text": [ "glutamate" ], "offsets": [ [ 61, 70 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "611" }, { "db_name": "PubChem", "db_id": "23327" }, { "db_name": "PubChem", "db_id": "33032" } ] }, { "id": "DS.d910.s1.e0", "type": "protein", "text": [ "pyruvate kinase" ], "offsets": [ [ 149, 164 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O05118" }, { "db_name": "UniProt", "db_id": "O06134" }, { "db_name": "UniProt", "db_id": "O08309" }, { "db_name": "UniProt", "db_id": "O44006" }, { "db_name": "UniProt", "db_id": "O51323" }, { "db_name": "UniProt", "db_id": "O62619" }, { "db_name": "UniProt", "db_id": "O94122" }, { "db_name": "UniProt", "db_id": "P19680" }, { "db_name": "UniProt", "db_id": "P22360" }, { "db_name": "UniProt", "db_id": "P30614" }, { "db_name": "UniProt", "db_id": "P31865" }, { "db_name": "UniProt", "db_id": "P32044" }, { "db_name": "UniProt", "db_id": "P34038" }, { "db_name": "UniProt", "db_id": "P43924" }, { "db_name": "UniProt", "db_id": "P46614" }, { "db_name": "UniProt", "db_id": "P47458" }, { "db_name": "UniProt", "db_id": "P51181" }, { "db_name": "UniProt", "db_id": "P51182" }, { "db_name": "UniProt", "db_id": "P57404" }, { "db_name": "UniProt", "db_id": "P70789" }, { "db_name": "UniProt", "db_id": "P78031" }, { "db_name": "UniProt", "db_id": "P80885" }, { "db_name": "UniProt", "db_id": "P81344" }, { "db_name": "UniProt", "db_id": "P94685" }, { "db_name": "UniProt", "db_id": "P94939" }, { "db_name": "UniProt", "db_id": "Q02499" }, { "db_name": "UniProt", "db_id": "Q04668" }, { "db_name": "UniProt", "db_id": "Q07637" }, { "db_name": "UniProt", "db_id": "Q10208" }, { "db_name": "UniProt", "db_id": "Q12669" }, { "db_name": "UniProt", "db_id": "Q27686" }, { "db_name": "UniProt", "db_id": "Q27788" }, { "db_name": "UniProt", "db_id": "Q44473" }, { "db_name": "UniProt", "db_id": "Q46078" }, { "db_name": "UniProt", "db_id": "Q46289" }, { "db_name": "UniProt", "db_id": "Q56301" }, { "db_name": "UniProt", "db_id": "Q57572" }, { "db_name": "UniProt", "db_id": "Q6BS75" }, { "db_name": "UniProt", "db_id": "Q759A9" }, { "db_name": "UniProt", "db_id": "Q7RVA8" }, { "db_name": "UniProt", "db_id": "Q875M9" }, { "db_name": "UniProt", "db_id": "Q875S4" }, { "db_name": "UniProt", "db_id": "Q875Z9" }, { "db_name": "UniProt", "db_id": "Q89AI8" }, { "db_name": "UniProt", "db_id": "Q8FP04" }, { "db_name": "UniProt", "db_id": "Q8K9M3" }, { "db_name": "UniProt", "db_id": "Q9PK61" }, { "db_name": "UniProt", "db_id": "Q9Z984" } ] }, { "id": "DS.d910.s1.e1", "type": "compound", "text": [ "glutamate" ], "offsets": [ [ 191, 200 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "611" }, { "db_name": "PubChem", "db_id": "23327" }, { "db_name": "PubChem", "db_id": "33032" } ] } ]
[]
[]
[ { "id": "DS.d910.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d910.s0.e1", "arg2_id": "DS.d910.s0.e0", "normalized": [] }, { "id": "DS.d910.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d910.s1.e1", "arg2_id": "DS.d910.s1.e0", "normalized": [] } ]
DS.d911
18751891
[ { "id": "DS.d911.s0", "type": "", "text": [ "We examined the expression of Phgdh and ASCT1 in kainic acid (KA)-induced neurodegeneration of the mouse hippocampus using immunohistochemistry and Western blots." ], "offsets": [ [ 0, 162 ] ] } ]
[ { "id": "DS.d911.s0.e0", "type": "protein", "text": [ "Phgdh" ], "offsets": [ [ 30, 35 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O08651" }, { "db_name": "UniProt", "db_id": "Q61753" } ] }, { "id": "DS.d911.s0.e1", "type": "protein", "text": [ "ASCT1" ], "offsets": [ [ 40, 45 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O35874" }, { "db_name": "UniProt", "db_id": "P43007" } ] }, { "id": "DS.d911.s0.e2", "type": "compound", "text": [ "kainic acid" ], "offsets": [ [ 49, 60 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "10255" } ] } ]
[]
[]
[ { "id": "DS.d911.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d911.s0.e2", "arg2_id": "DS.d911.s0.e0", "normalized": [] }, { "id": "DS.d911.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d911.s0.e2", "arg2_id": "DS.d911.s0.e1", "normalized": [] } ]
DS.d912
18751892
[ { "id": "DS.d912.s0", "type": "", "text": [ "In the present study the effect of the convulsant drug 3-mercaptopropionic acid (MP) repetitive administration (4-7 days) on the hippocampal NR2B subunit was studied." ], "offsets": [ [ 0, 166 ] ] }, { "id": "DS.d912.s1", "type": "", "text": [ "A significant decrease in NR2B in the whole hippocampus was observed after MP4 with a tendency to recover to normal values in MP7 by western blot assay." ], "offsets": [ [ 167, 319 ] ] } ]
[ { "id": "DS.d912.s0.e0", "type": "compound", "text": [ "3-mercaptopropionic acid" ], "offsets": [ [ 55, 79 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6514" } ] }, { "id": "DS.d912.s0.e1", "type": "protein", "text": [ "NR2B" ], "offsets": [ [ 141, 145 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q00960" }, { "db_name": "UniProt", "db_id": "Q01097" }, { "db_name": "UniProt", "db_id": "Q13224" } ] }, { "id": "DS.d912.s1.e0", "type": "protein", "text": [ "NR2B" ], "offsets": [ [ 193, 197 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q00960" }, { "db_name": "UniProt", "db_id": "Q01097" }, { "db_name": "UniProt", "db_id": "Q13224" } ] }, { "id": "DS.d912.s1.e1", "type": "compound", "text": [ "MP7" ], "offsets": [ [ 293, 296 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "49766501" } ] } ]
[]
[]
[ { "id": "DS.d912.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d912.s0.e0", "arg2_id": "DS.d912.s0.e1", "normalized": [] }, { "id": "DS.d912.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d912.s1.e1", "arg2_id": "DS.d912.s1.e0", "normalized": [] } ]
DS.d913
18751894
[ { "id": "DS.d913.s0", "type": "", "text": [ "Heart glycogen represents a store of glucosyl residues which are mobilized by the catalysis of glycogen phosphorylase (GP) and are mainly destined to serve as substrates for the generation of ATP." ], "offsets": [ [ 0, 196 ] ] } ]
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[]
[]
[]
DS.d914
18752001
[ { "id": "DS.d914.s0", "type": "", "text": [ "However, phenformin was equally effective in AMPKalpha1(-/-) and wild-type animals, suggesting additional AMPK-independent action of phenformin." ], "offsets": [ [ 0, 144 ] ] } ]
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[]
[]
[]
DS.d915
18752070
[ { "id": "DS.d915.s0", "type": "", "text": [ "The relationship between prolactin (PRL), leptin, nitric oxide (NO), and cytokines in patients with hyperprolactinemia." ], "offsets": [ [ 0, 119 ] ] }, { "id": "DS.d915.s1", "type": "", "text": [ "The aim of this study was to determine the changes in serum leptin, tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), nitric oxide (NO) levels in patients with hyperprolactinemia." ], "offsets": [ [ 120, 312 ] ] } ]
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"db_id": "Q8JFG3" }, { "db_name": "UniProt", "db_id": "Q8MKG8" }, { "db_name": "UniProt", "db_id": "Q8WNR1" }, { "db_name": "UniProt", "db_id": "Q9BEA1" } ] }, { "id": "DS.d915.s1.e3", "type": "protein", "text": [ "interleukin-6" ], "offsets": [ [ 229, 242 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P41693" } ] }, { "id": "DS.d915.s1.e4", "type": "protein", "text": [ "IL-6" ], "offsets": [ [ 244, 248 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O35736" }, { "db_name": "UniProt", "db_id": "P05231" }, { "db_name": "UniProt", "db_id": "P08505" }, { "db_name": "UniProt", "db_id": "P20607" }, { "db_name": "UniProt", "db_id": "P26892" }, { "db_name": "UniProt", "db_id": "P26893" }, { "db_name": "UniProt", "db_id": "P29455" }, { "db_name": "UniProt", "db_id": "P41323" }, { "db_name": "UniProt", "db_id": "P41683" }, { "db_name": "UniProt", "db_id": "P41693" }, { "db_name": "UniProt", "db_id": "P46650" }, { "db_name": "UniProt", "db_id": "P51494" }, { "db_name": "UniProt", "db_id": "P79341" }, { "db_name": "UniProt", "db_id": "Q25BC2" }, { "db_name": "UniProt", "db_id": "Q28319" }, { "db_name": "UniProt", "db_id": "Q28747" }, { "db_name": "UniProt", "db_id": "Q28819" }, { "db_name": "UniProt", "db_id": "Q2MH06" }, { "db_name": "UniProt", "db_id": "Q5I6E3" }, { "db_name": "UniProt", "db_id": "Q6V919" }, { "db_name": "UniProt", "db_id": "Q865W7" }, { "db_name": "UniProt", "db_id": "Q865X6" }, { "db_name": "UniProt", "db_id": "Q8MKH0" }, { "db_name": "UniProt", "db_id": "Q95181" }, { "db_name": "UniProt", "db_id": "Q9MZR1" }, { "db_name": "UniProt", "db_id": "Q9XT80" } ] }, { "id": "DS.d915.s1.e5", "type": "compound", "text": [ "nitric oxide" ], "offsets": [ [ 251, 263 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "145068" } ] } ]
[]
[]
[]
DS.d916
18752089
[ { "id": "DS.d916.s0", "type": "", "text": [ "Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant-174G>C with circulating glucose levels, interleukin-6 levels, and body mass index." ], "offsets": [ [ 0, 187 ] ] } ]
[ { "id": "DS.d916.s0.e0", "type": "protein", "text": [ "IL6" ], "offsets": [ [ 90, 93 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O35736" }, { "db_name": "UniProt", "db_id": "P05231" }, { "db_name": "UniProt", "db_id": "P26892" }, { "db_name": "UniProt", "db_id": "P26893" }, { "db_name": "UniProt", "db_id": "P29455" }, { "db_name": "UniProt", "db_id": "P41323" }, { "db_name": "UniProt", "db_id": "P41683" }, { "db_name": "UniProt", "db_id": "P41693" }, { "db_name": "UniProt", "db_id": "P46650" }, { "db_name": "UniProt", "db_id": "P51494" }, { "db_name": "UniProt", "db_id": "P79341" }, { "db_name": "UniProt", "db_id": "Q25BC2" }, { "db_name": "UniProt", "db_id": "Q28319" }, { "db_name": "UniProt", "db_id": "Q28747" }, { "db_name": "UniProt", "db_id": "Q28819" }, { "db_name": "UniProt", "db_id": "Q2MH06" }, { "db_name": "UniProt", "db_id": "Q5I6E3" }, { "db_name": "UniProt", "db_id": "Q6V919" }, { "db_name": "UniProt", "db_id": "Q865W7" }, { "db_name": "UniProt", "db_id": "Q865X6" }, { "db_name": "UniProt", "db_id": "Q8MKH0" }, { "db_name": "UniProt", "db_id": "Q95181" }, { "db_name": "UniProt", "db_id": "Q9MZR1" }, { "db_name": "UniProt", "db_id": "Q9XT80" } ] }, { "id": "DS.d916.s0.e1", "type": "compound", "text": [ "glucose" ], "offsets": [ [ 129, 136 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "206" }, { "db_name": "PubChem", "db_id": "5793" }, { "db_name": "PubChem", "db_id": "64689" }, { "db_name": "PubChem", "db_id": "79025" } ] }, { "id": "DS.d916.s0.e2", "type": "protein", "text": [ "interleukin-6" ], "offsets": [ [ 145, 158 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P41693" } ] } ]
[]
[]
[]
DS.d917
18752284
[ { "id": "DS.d917.s0", "type": "", "text": [ "Effect of cytochrome P450 3A5 *3 genotype on the stereoselective pharmacokinetics of amlodipine in healthy subjects." ], "offsets": [ [ 0, 116 ] ] }, { "id": "DS.d917.s1", "type": "", "text": [ "In conclusion, the present study showed that despite the evidence that amlodipine is stereoselectively metabolized, CYP3A5 *3 genotype did not affect stereoselective disposition of amlodipine." ], "offsets": [ [ 117, 309 ] ] }, { "id": "DS.d917.s2", "type": "", "text": [ "It provides the evidence that CYP3A5 *3genotype plays a minor role in the interindividual variability of stereoselective disposition of amlodipine in humans." ], "offsets": [ [ 310, 467 ] ] } ]
[ { "id": "DS.d917.s0.e0", "type": "protein", "text": [ "cytochrome P450 3A5" ], "offsets": [ [ 10, 29 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P20815" }, { "db_name": "UniProt", "db_id": "P80056" } ] }, { "id": "DS.d917.s0.e1", "type": "compound", "text": [ "amlodipine" ], "offsets": [ [ 85, 95 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2162" } ] }, { "id": "DS.d917.s1.e0", "type": "compound", "text": [ "amlodipine" ], "offsets": [ [ 188, 198 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2162" } ] }, { "id": "DS.d917.s1.e1", "type": "protein", "text": [ "CYP3A5" ], "offsets": [ [ 233, 239 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P20815" } ] }, { "id": "DS.d917.s1.e2", "type": "compound", "text": [ "amlodipine" ], "offsets": [ [ 298, 308 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2162" } ] }, { "id": "DS.d917.s2.e0", "type": "protein", "text": [ "CYP3A5" ], "offsets": [ [ 340, 346 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P20815" } ] }, { "id": "DS.d917.s2.e1", "type": "compound", "text": [ "amlodipine" ], "offsets": [ [ 446, 456 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2162" } ] } ]
[]
[]
[ { "id": "DS.d917.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d917.s0.e1", "arg2_id": "DS.d917.s0.e0", "normalized": [] }, { "id": "DS.d917.s2.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d917.s2.e1", "arg2_id": "DS.d917.s2.e0", "normalized": [] } ]
DS.d918
18752291
[ { "id": "DS.d918.s0", "type": "", "text": [ "Tissues were stained for BrdU, Pax-7, vimentin, and haematoxylin and eosin staining." ], "offsets": [ [ 0, 84 ] ] } ]
[ { "id": "DS.d918.s0.e0", "type": "compound", "text": [ "BrdU" ], "offsets": [ [ 25, 29 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6035" } ] }, { "id": "DS.d918.s0.e1", "type": "protein", "text": [ "Pax-7" ], "offsets": [ [ 31, 36 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P47239" } ] }, { "id": "DS.d918.s0.e2", "type": "protein", "text": [ "vimentin" ], "offsets": [ [ 38, 46 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02543" }, { "db_name": "UniProt", "db_id": "P02544" }, { "db_name": "UniProt", "db_id": "P08670" }, { "db_name": "UniProt", "db_id": "P09654" }, { "db_name": "UniProt", "db_id": "P20152" }, { "db_name": "UniProt", "db_id": "P31000" }, { "db_name": "UniProt", "db_id": "P48616" }, { "db_name": "UniProt", "db_id": "P48670" }, { "db_name": "UniProt", "db_id": "P48674" }, { "db_name": "UniProt", "db_id": "P84198" }, { "db_name": "UniProt", "db_id": "Q4R4X4" }, { "db_name": "UniProt", "db_id": "Q5R1W8" }, { "db_name": "UniProt", "db_id": "Q92155" }, { "db_name": "UniProt", "db_id": "Q9MZA9" } ] }, { "id": "DS.d918.s0.e3", "type": "compound", "text": [ "haematoxylin" ], "offsets": [ [ 52, 64 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "442514" } ] } ]
[]
[]
[]
DS.d919
18752295
[ { "id": "DS.d919.s0", "type": "", "text": [ "Differences in the expression of inwardly rectifying potassium channels (Kir4.1), glial fibrillary acidic protein (GFAP), and taurine levels in cortical astrocytes were detected using immunohistochemical methods." ], "offsets": [ [ 0, 212 ] ] }, { "id": "DS.d919.s1", "type": "", "text": [ "Immunohistochemical analysis suggests that the diverse expression of Kir4.1 channels and GFAP as well as differences in the accumulation of taurine might contribute to the distinct ability of astrocytes to regulate their volume." ], "offsets": [ [ 213, 441 ] ] } ]
[ { "id": "DS.d919.s0.e0", "type": "protein", "text": [ "Kir4.1" ], "offsets": [ [ 73, 79 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P49655" } ] }, { "id": "DS.d919.s0.e1", "type": "protein", "text": [ "acidic protein" ], "offsets": [ [ 99, 113 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01538" }, { "db_name": "UniProt", "db_id": "P01543" }, { "db_name": "UniProt", "db_id": "P01544" }, { "db_name": "UniProt", "db_id": "P01545" }, { "db_name": "UniProt", "db_id": "P08772" }, { "db_name": "UniProt", "db_id": "P08943" }, { "db_name": "UniProt", "db_id": "P09617" }, { "db_name": "UniProt", "db_id": "P09618" }, { "db_name": "UniProt", "db_id": "P21742" }, { "db_name": "UniProt", "db_id": "P32032" }, { "db_name": "UniProt", "db_id": "Q05806" }, { "db_name": "UniProt", "db_id": "Q42596" }, { "db_name": "UniProt", "db_id": "Q42597" }, { "db_name": "UniProt", "db_id": "Q42838" }, { "db_name": "UniProt", "db_id": "Q8H0Q5" }, { "db_name": "UniProt", "db_id": "Q8VZK8" }, { "db_name": "UniProt", "db_id": "Q9C8D6" }, { "db_name": "UniProt", "db_id": "Q9SBK8" } ] }, { "id": "DS.d919.s0.e2", "type": "protein", "text": [ "GFAP" ], "offsets": [ [ 115, 119 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P03995" }, { "db_name": "UniProt", "db_id": "P14136" }, { "db_name": "UniProt", "db_id": "P47819" }, { "db_name": "UniProt", "db_id": "Q28115" } ] }, { "id": "DS.d919.s0.e3", "type": "compound", "text": [ "taurine" ], "offsets": [ [ 126, 133 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1123" } ] }, { "id": "DS.d919.s1.e0", "type": "protein", "text": [ "Kir4.1" ], "offsets": [ [ 282, 288 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P49655" } ] }, { "id": "DS.d919.s1.e1", "type": "protein", "text": [ "GFAP" ], "offsets": [ [ 302, 306 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P03995" }, { "db_name": "UniProt", "db_id": "P14136" }, { "db_name": "UniProt", "db_id": "P47819" }, { "db_name": "UniProt", "db_id": "Q28115" } ] }, { "id": "DS.d919.s1.e2", "type": "compound", "text": [ "taurine" ], "offsets": [ [ 353, 360 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "1123" } ] } ]
[]
[]
[]
DS.d920
18752301
[ { "id": "DS.d920.s0", "type": "", "text": [ "These evoked expressions at both molecular and cellular levels were significantly inhibited after TRPV(1) receptors were blocked by 5'-iodoresiniferatoxin (5 microg) or PKC was inhibited by chelerythrine chloride (5 microg)." ], "offsets": [ [ 0, 224 ] ] } ]
[ { "id": "DS.d920.s0.e0", "type": "compound", "text": [ "5'-iodoresiniferatoxin" ], "offsets": [ [ 132, 154 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "16219535" } ] }, { "id": "DS.d920.s0.e1", "type": "protein", "text": [ "PKC" ], "offsets": [ [ 169, 172 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P05130" }, { "db_name": "UniProt", "db_id": "P13677" }, { "db_name": "UniProt", "db_id": "P13678" }, { "db_name": "UniProt", "db_id": "P34722" } ] }, { "id": "DS.d920.s0.e2", "type": "compound", "text": [ "chelerythrine" ], "offsets": [ [ 190, 203 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "2703" }, { "db_name": "PubChem", "db_id": "411938" } ] }, { "id": "DS.d920.s0.e3", "type": "compound", "text": [ "chloride" ], "offsets": [ [ 204, 212 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "312" } ] } ]
[]
[]
[ { "id": "DS.d920.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d920.s0.e2", "arg2_id": "DS.d920.s0.e1", "normalized": [] }, { "id": "DS.d920.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d920.s0.e3", "arg2_id": "DS.d920.s0.e1", "normalized": [] } ]
DS.d921
18752305
[ { "id": "DS.d921.s0", "type": "", "text": [ "Regulation of the phosphoinositide-3 kinase and mitogen-activated protein kinase signaling pathways by progesterone and its reduced metabolites in the rat brain." ], "offsets": [ [ 0, 161 ] ] }, { "id": "DS.d921.s1", "type": "", "text": [ "Several growth factors, such as vascular endothelial growth factor, brain-derived neurotrophic factor, and insulin-like growth factor-I are involved in the actions of progesterone in the central nervous system." ], "offsets": [ [ 162, 372 ] ] }, { "id": "DS.d921.s2", "type": "", "text": [ "Significant increases in the phosphorylation of ERK, in the expression of the catalytic (p110) and the regulatory (p85) subunits of PI3K and in the phosphorylation of Akt were observed in the hypothalamus, the hippocampus, and the cerebellum 24 hr after progesterone administration." ], "offsets": [ [ 373, 655 ] ] } ]
[ { "id": "DS.d921.s0.e0", "type": "protein", "text": [ "mitogen-activated protein kinase" ], "offsets": [ [ 48, 80 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q00859" } ] }, { "id": "DS.d921.s0.e1", "type": "compound", "text": [ "progesterone" ], "offsets": [ [ 103, 115 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5994" } ] }, { "id": "DS.d921.s1.e0", "type": "protein", "text": [ "brain-derived neurotrophic factor" ], "offsets": [ [ 230, 263 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P25430" }, { "db_name": "UniProt", "db_id": "P25431" }, { "db_name": "UniProt", "db_id": "P25432" }, { "db_name": "UniProt", "db_id": "Q06225" } ] }, { "id": "DS.d921.s1.e1", "type": "protein", "text": [ "insulin" ], "offsets": [ [ 269, 276 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P01314" }, { "db_name": "UniProt", "db_id": "P01316" }, { "db_name": "UniProt", "db_id": "P01319" }, { "db_name": "UniProt", "db_id": "P01320" }, { "db_name": "UniProt", "db_id": "P01324" }, { "db_name": "UniProt", "db_id": "P01328" }, { "db_name": "UniProt", "db_id": "P01330" }, { "db_name": "UniProt", "db_id": "P01331" }, { "db_name": "UniProt", "db_id": "P01334" }, { "db_name": "UniProt", "db_id": "P01336" }, { "db_name": "UniProt", "db_id": "P01340" }, { "db_name": "UniProt", "db_id": "P07453" }, { "db_name": "UniProt", "db_id": "P09476" }, { "db_name": "UniProt", "db_id": "P09477" }, { "db_name": "UniProt", "db_id": "P0C236" }, { "db_name": "UniProt", "db_id": "P12703" }, { "db_name": "UniProt", "db_id": "P12704" }, { "db_name": "UniProt", "db_id": "P12708" }, { "db_name": "UniProt", "db_id": "P13190" }, { "db_name": "UniProt", "db_id": "P18109" }, { "db_name": "UniProt", "db_id": "P29335" }, { "db_name": "UniProt", "db_id": "P42633" }, { "db_name": "UniProt", "db_id": "P67968" }, { "db_name": "UniProt", "db_id": "P67969" }, { "db_name": "UniProt", "db_id": "P67971" }, { "db_name": "UniProt", "db_id": "P67973" }, { "db_name": "UniProt", "db_id": "P67974" }, { "db_name": "UniProt", "db_id": "P68243" }, { "db_name": "UniProt", "db_id": "P68245" }, { "db_name": "UniProt", "db_id": "P68987" }, { "db_name": "UniProt", "db_id": "P68988" }, { "db_name": "UniProt", "db_id": "P68989" }, { "db_name": "UniProt", "db_id": "P68990" }, { "db_name": "UniProt", "db_id": "P68991" }, { "db_name": "UniProt", "db_id": "P68992" }, { "db_name": "UniProt", "db_id": "P69046" }, { "db_name": "UniProt", "db_id": "P69047" }, { "db_name": "UniProt", "db_id": "P69048" }, { "db_name": "UniProt", "db_id": "P81423" }, { "db_name": "UniProt", "db_id": "P81881" }, { "db_name": "UniProt", "db_id": "Q9TQY7" } ] }, { "id": "DS.d921.s1.e2", "type": "compound", "text": [ "progesterone" ], "offsets": [ [ 329, 341 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5994" } ] }, { "id": "DS.d921.s2.e0", "type": "protein", "text": [ "ERK" ], "offsets": [ [ 421, 424 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P29323" } ] }, { "id": "DS.d921.s2.e1", "type": "protein", "text": [ "p110" ], "offsets": [ [ 462, 466 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P07566" }, { "db_name": "UniProt", "db_id": "P08563" }, { "db_name": "UniProt", "db_id": "P08564" }, { "db_name": "UniProt", "db_id": "P14907" }, { "db_name": "UniProt", "db_id": "P19725" }, { "db_name": "UniProt", "db_id": "P47825" }, { "db_name": "UniProt", "db_id": "Q6X2U1" }, { "db_name": "UniProt", "db_id": "Q6X2U3" }, { "db_name": "UniProt", "db_id": "Q8VA10" }, { "db_name": "UniProt", "db_id": "Q99IE6" }, { "db_name": "UniProt", "db_id": "Q9J6K8" } ] }, { "id": "DS.d921.s2.e2", "type": "protein", "text": [ "p85" ], "offsets": [ [ 488, 491 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O43439" }, { "db_name": "UniProt", "db_id": "P46655" }, { "db_name": "UniProt", "db_id": "P49846" }, { "db_name": "UniProt", "db_id": "Q14155" } ] }, { "id": "DS.d921.s2.e3", "type": "protein", "text": [ "PI3K" ], "offsets": [ [ 505, 509 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O00329" }, { "db_name": "UniProt", "db_id": "O02697" }, { "db_name": "UniProt", "db_id": "O35904" }, { "db_name": "UniProt", "db_id": "P23727" }, { "db_name": "UniProt", "db_id": "P26450" }, { "db_name": "UniProt", "db_id": "P27986" }, { "db_name": "UniProt", "db_id": "P32871" }, { "db_name": "UniProt", "db_id": "P42336" }, { "db_name": "UniProt", "db_id": "P42337" }, { "db_name": "UniProt", "db_id": "P42338" }, { "db_name": "UniProt", "db_id": "P42347" }, { "db_name": "UniProt", "db_id": "P42348" }, { "db_name": "UniProt", "db_id": "P48736" }, { "db_name": "UniProt", "db_id": "P54673" }, { "db_name": "UniProt", "db_id": "P54674" }, { "db_name": "UniProt", "db_id": "P54675" }, { "db_name": "UniProt", "db_id": "P54676" }, { "db_name": "UniProt", "db_id": "Q63787" }, { "db_name": "UniProt", "db_id": "Q8BTI9" }, { "db_name": "UniProt", "db_id": "Q8UUU2" }, { "db_name": "UniProt", "db_id": "Q9JHG7" }, { "db_name": "UniProt", "db_id": "Q9Z1L0" } ] }, { "id": "DS.d921.s2.e4", "type": "protein", "text": [ "Akt" ], "offsets": [ [ 540, 543 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P31750" }, { "db_name": "UniProt", "db_id": "Q8INB9" } ] }, { "id": "DS.d921.s2.e5", "type": "compound", "text": [ "progesterone" ], "offsets": [ [ 627, 639 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5994" } ] } ]
[]
[]
[ { "id": "DS.d921.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s0.e1", "arg2_id": "DS.d921.s0.e0", "normalized": [] }, { "id": "DS.d921.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s1.e2", "arg2_id": "DS.d921.s1.e0", "normalized": [] }, { "id": "DS.d921.s1.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s1.e2", "arg2_id": "DS.d921.s1.e1", "normalized": [] }, { "id": "DS.d921.s2.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s2.e5", "arg2_id": "DS.d921.s2.e0", "normalized": [] }, { "id": "DS.d921.s2.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s2.e5", "arg2_id": "DS.d921.s2.e2", "normalized": [] }, { "id": "DS.d921.s2.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s2.e5", "arg2_id": "DS.d921.s2.e1", "normalized": [] }, { "id": "DS.d921.s2.i3", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s2.e5", "arg2_id": "DS.d921.s2.e4", "normalized": [] }, { "id": "DS.d921.s2.i4", "type": "compound-protein-interaction", "arg1_id": "DS.d921.s2.e5", "arg2_id": "DS.d921.s2.e3", "normalized": [] } ]
DS.d922
18752414
[ { "id": "DS.d922.s0", "type": "", "text": [ "In addition, we used PET to evaluate the striatal dopamine transporter availability (DAT) with ((11)C)d-threo-methylphenidate in the patient group." ], "offsets": [ [ 0, 147 ] ] } ]
[ { "id": "DS.d922.s0.e0", "type": "protein", "text": [ "DAT" ], "offsets": [ [ 85, 88 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P13483" }, { "db_name": "UniProt", "db_id": "P23977" }, { "db_name": "UniProt", "db_id": "P27922" }, { "db_name": "UniProt", "db_id": "Q01959" }, { "db_name": "UniProt", "db_id": "Q03614" }, { "db_name": "UniProt", "db_id": "Q61327" }, { "db_name": "UniProt", "db_id": "Q9GJT6" } ] }, { "id": "DS.d922.s0.e1", "type": "compound", "text": [ "methylphenidate" ], "offsets": [ [ 110, 125 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "4158" } ] } ]
[]
[]
[ { "id": "DS.d922.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d922.s0.e1", "arg2_id": "DS.d922.s0.e0", "normalized": [] } ]
DS.d923
18752468
[ { "id": "DS.d923.s0", "type": "", "text": [ "Associated with the mitochondrial permeabilization, PdC also induced the release of cytochrome c, which is sensitive to inhibition by DTT." ], "offsets": [ [ 0, 138 ] ] } ]
[ { "id": "DS.d923.s0.e0", "type": "protein", "text": [ "cytochrome c" ], "offsets": [ [ 84, 96 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O07091" }, { "db_name": "UniProt", "db_id": "O13393" }, { "db_name": "UniProt", "db_id": "O22642" }, { "db_name": "UniProt", "db_id": "O93863" }, { "db_name": "UniProt", "db_id": "P00002" }, { "db_name": "UniProt", "db_id": "P00003" }, { "db_name": "UniProt", "db_id": "P00004" }, { "db_name": "UniProt", "db_id": "P00007" }, { "db_name": "UniProt", "db_id": "P00008" }, { "db_name": "UniProt", "db_id": "P00011" }, { "db_name": "UniProt", "db_id": "P00012" }, { "db_name": "UniProt", "db_id": "P00013" }, { "db_name": "UniProt", "db_id": "P00014" }, { "db_name": "UniProt", "db_id": "P00017" }, { "db_name": "UniProt", "db_id": "P00018" }, { "db_name": "UniProt", "db_id": "P00019" }, { "db_name": "UniProt", "db_id": "P00020" }, { "db_name": "UniProt", "db_id": "P00021" }, { "db_name": "UniProt", "db_id": "P00022" }, { "db_name": "UniProt", "db_id": "P00024" }, { "db_name": "UniProt", "db_id": "P00025" }, { "db_name": "UniProt", "db_id": "P00027" }, { "db_name": "UniProt", "db_id": "P00028" }, { "db_name": "UniProt", "db_id": "P00029" }, { "db_name": "UniProt", "db_id": "P00030" }, { "db_name": "UniProt", "db_id": "P00031" }, { "db_name": "UniProt", "db_id": "P00032" }, { "db_name": "UniProt", "db_id": "P00035" }, { "db_name": "UniProt", "db_id": "P00036" }, { "db_name": "UniProt", "db_id": "P00037" }, { "db_name": "UniProt", "db_id": "P00038" }, { "db_name": "UniProt", "db_id": "P00039" }, { "db_name": "UniProt", "db_id": "P00040" }, { "db_name": "UniProt", "db_id": "P00041" }, { "db_name": "UniProt", "db_id": "P00042" }, { "db_name": "UniProt", "db_id": "P00043" }, { "db_name": "UniProt", "db_id": "P00046" }, { "db_name": "UniProt", "db_id": "P00047" }, { "db_name": "UniProt", "db_id": "P00048" }, { "db_name": "UniProt", "db_id": "P00049" }, { "db_name": "UniProt", "db_id": "P00051" }, { "db_name": "UniProt", "db_id": "P00052" }, { "db_name": "UniProt", "db_id": "P00053" }, { "db_name": "UniProt", "db_id": "P00054" }, { "db_name": "UniProt", "db_id": "P00055" }, { "db_name": "UniProt", "db_id": "P00056" }, { "db_name": "UniProt", "db_id": "P00057" }, { "db_name": "UniProt", "db_id": "P00058" }, { "db_name": "UniProt", "db_id": "P00059" }, { "db_name": "UniProt", "db_id": "P00060" }, { "db_name": "UniProt", "db_id": "P00061" }, { "db_name": "UniProt", "db_id": "P00062" }, { "db_name": "UniProt", "db_id": "P00063" }, { "db_name": "UniProt", "db_id": "P00064" }, { "db_name": "UniProt", "db_id": "P00065" }, { "db_name": "UniProt", "db_id": "P00066" }, { "db_name": "UniProt", "db_id": "P00067" }, { "db_name": "UniProt", "db_id": "P00068" }, { "db_name": "UniProt", "db_id": "P00069" }, { "db_name": "UniProt", "db_id": "P00070" }, { "db_name": "UniProt", "db_id": "P00071" }, { "db_name": "UniProt", "db_id": "P00072" }, { "db_name": "UniProt", "db_id": "P00073" }, { "db_name": "UniProt", "db_id": "P00074" }, { "db_name": "UniProt", "db_id": "P00075" }, { "db_name": "UniProt", "db_id": "P00076" }, { "db_name": "UniProt", "db_id": "P00077" }, { "db_name": "UniProt", "db_id": "P00078" }, { "db_name": "UniProt", "db_id": "P00079" }, { "db_name": "UniProt", "db_id": "P12831" }, { "db_name": "UniProt", "db_id": "P15451" }, { "db_name": "UniProt", "db_id": "P18822" }, { "db_name": "UniProt", "db_id": "P19681" }, { "db_name": "UniProt", "db_id": "P19974" }, { "db_name": "UniProt", "db_id": "P21665" }, { "db_name": "UniProt", "db_id": "P22342" }, { "db_name": "UniProt", "db_id": "P25400" }, { "db_name": "UniProt", "db_id": "P29380" }, { "db_name": "UniProt", "db_id": "P32556" }, { "db_name": "UniProt", "db_id": "P38091" }, { "db_name": "UniProt", "db_id": "P53698" }, { "db_name": "UniProt", "db_id": "P56205" }, { "db_name": "UniProt", "db_id": "P59218" }, { "db_name": "UniProt", "db_id": "P62772" }, { "db_name": "UniProt", "db_id": "P62773" }, { "db_name": "UniProt", "db_id": "P62894" }, { "db_name": "UniProt", "db_id": "P62895" }, { "db_name": "UniProt", "db_id": "P62896" }, { "db_name": "UniProt", "db_id": "P67881" }, { "db_name": "UniProt", "db_id": "P67882" }, { "db_name": "UniProt", "db_id": "P68096" }, { "db_name": "UniProt", "db_id": "P68097" }, { "db_name": "UniProt", "db_id": "P68098" }, { "db_name": "UniProt", "db_id": "P68099" }, { "db_name": "UniProt", "db_id": "P68100" }, { "db_name": "UniProt", "db_id": "P68517" }, { "db_name": "UniProt", "db_id": "P68518" }, { "db_name": "UniProt", "db_id": "P68519" }, { "db_name": "UniProt", "db_id": "P81280" }, { "db_name": "UniProt", "db_id": "P81459" }, { "db_name": "UniProt", "db_id": "P99998" }, { "db_name": "UniProt", "db_id": "P99999" }, { "db_name": "UniProt", "db_id": "Q41346" }, { "db_name": "UniProt", "db_id": "Q4HVX7" }, { "db_name": "UniProt", "db_id": "Q52V08" }, { "db_name": "UniProt", "db_id": "Q52V09" }, { "db_name": "UniProt", "db_id": "Q52V10" }, { "db_name": "UniProt", "db_id": "Q5RFH4" }, { "db_name": "UniProt", "db_id": "Q640U4" }, { "db_name": "UniProt", "db_id": "Q6C9Q0" }, { "db_name": "UniProt", "db_id": "Q6IQM2" }, { "db_name": "UniProt", "db_id": "Q6Q4H8" }, { "db_name": "UniProt", "db_id": "Q6QLW4" }, { "db_name": "UniProt", "db_id": "Q6WUX8" }, { "db_name": "UniProt", "db_id": "Q753F4" }, { "db_name": "UniProt", "db_id": "Q7YR71" }, { "db_name": "UniProt", "db_id": "Q96VP3" } ] }, { "id": "DS.d923.s0.e1", "type": "compound", "text": [ "DTT" ], "offsets": [ [ 134, 137 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "439352" } ] } ]
[]
[]
[ { "id": "DS.d923.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d923.s0.e1", "arg2_id": "DS.d923.s0.e0", "normalized": [] } ]
DS.d924
18752565
[ { "id": "DS.d924.s0", "type": "", "text": [ "Toll-like receptor 4 (TLR-4)/myeloid differentiation protein-2 complex ligation by lipopolysaccharide induces production of pro-inflammatory cytokines and co-stimulatory molecules on antigen presenting cells." ], "offsets": [ [ 0, 208 ] ] } ]
[ { "id": "DS.d924.s0.e0", "type": "protein", "text": [ "TLR" ], "offsets": [ [ 22, 25 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P23799" } ] }, { "id": "DS.d924.s0.e1", "type": "protein", "text": [ "protein-2" ], "offsets": [ [ 53, 62 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P03548" }, { "db_name": "UniProt", "db_id": "P03549" }, { "db_name": "UniProt", "db_id": "P03550" }, { "db_name": "UniProt", "db_id": "P05397" }, { "db_name": "UniProt", "db_id": "P09521" }, { "db_name": "UniProt", "db_id": "P19818" }, { "db_name": "UniProt", "db_id": "Q00965" }, { "db_name": "UniProt", "db_id": "Q01087" }, { "db_name": "UniProt", "db_id": "Q02966" } ] }, { "id": "DS.d924.s0.e2", "type": "compound", "text": [ "lipopolysaccharide" ], "offsets": [ [ 83, 101 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "11970143" } ] } ]
[]
[]
[ { "id": "DS.d924.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d924.s0.e2", "arg2_id": "DS.d924.s0.e0", "normalized": [] }, { "id": "DS.d924.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d924.s0.e2", "arg2_id": "DS.d924.s0.e1", "normalized": [] } ]
DS.d925
18752633
[ { "id": "DS.d925.s0", "type": "", "text": [ "Immunohistochemistry was performed on paraffin-embedded sections, using anti-5-methylcytosine (5mc) and anti-Acetyl-Histone H3 (Lys 9)." ], "offsets": [ [ 0, 135 ] ] } ]
[ { "id": "DS.d925.s0.e0", "type": "compound", "text": [ "5-methylcytosine" ], "offsets": [ [ 77, 93 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "65040" } ] }, { "id": "DS.d925.s0.e1", "type": "protein", "text": [ "Histone H3" ], "offsets": [ [ 116, 126 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P02299" }, { "db_name": "UniProt", "db_id": "P07041" }, { "db_name": "UniProt", "db_id": "P08437" }, { "db_name": "UniProt", "db_id": "P08898" }, { "db_name": "UniProt", "db_id": "P22843" }, { "db_name": "UniProt", "db_id": "P23753" }, { "db_name": "UniProt", "db_id": "P40285" }, { "db_name": "UniProt", "db_id": "P50564" }, { "db_name": "UniProt", "db_id": "P61830" }, { "db_name": "UniProt", "db_id": "P61831" }, { "db_name": "UniProt", "db_id": "P61832" }, { "db_name": "UniProt", "db_id": "P61833" }, { "db_name": "UniProt", "db_id": "P61834" }, { "db_name": "UniProt", "db_id": "P61835" }, { "db_name": "UniProt", "db_id": "P61836" }, { "db_name": "UniProt", "db_id": "P80553" }, { "db_name": "UniProt", "db_id": "P83864" }, { "db_name": "UniProt", "db_id": "P84235" }, { "db_name": "UniProt", "db_id": "P84236" }, { "db_name": "UniProt", "db_id": "P84237" }, { "db_name": "UniProt", "db_id": "P84238" }, { "db_name": "UniProt", "db_id": "P84239" }, { "db_name": "UniProt", "db_id": "P90543" }, { "db_name": "UniProt", "db_id": "Q06196" }, { "db_name": "UniProt", "db_id": "Q2UCQ0" }, { "db_name": "UniProt", "db_id": "Q5DWI3" }, { "db_name": "UniProt", "db_id": "Q757N1" }, { "db_name": "UniProt", "db_id": "Q7XYZ0" }, { "db_name": "UniProt", "db_id": "Q98RY4" }, { "db_name": "UniProt", "db_id": "Q9HDN1" }, { "db_name": "UniProt", "db_id": "Q9P427" }, { "db_name": "UniProt", "db_id": "Q9U7D1" } ] } ]
[]
[]
[]
DS.d926
18752635
[ { "id": "DS.d926.s0", "type": "", "text": [ "Here, the NCX-mediated (45)Ca(2+) uptake was compared in Na (+)-loaded pig coronary artery smooth muscle and endothelial cells." ], "offsets": [ [ 0, 127 ] ] }, { "id": "DS.d926.s1", "type": "", "text": [ "The concept of a linkage between NCX and SERCA in smooth muscle was also confirmed by similar distribution of NCX and SERCA2 proteins when detergent-treated microsomes were fractionated by flotation on sucrose density gradients." ], "offsets": [ [ 128, 356 ] ] } ]
[ { "id": "DS.d926.s0.e0", "type": "protein", "text": [ "NCX" ], "offsets": [ [ 10, 13 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O43763" } ] }, { "id": "DS.d926.s0.e1", "type": "compound", "text": [ "Na" ], "offsets": [ [ 57, 59 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "923" }, { "db_name": "PubChem", "db_id": "373840" } ] }, { "id": "DS.d926.s1.e0", "type": "protein", "text": [ "NCX" ], "offsets": [ [ 161, 164 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O43763" } ] }, { "id": "DS.d926.s1.e1", "type": "protein", "text": [ "NCX" ], "offsets": [ [ 238, 241 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O43763" } ] }, { "id": "DS.d926.s1.e2", "type": "protein", "text": [ "SERCA2" ], "offsets": [ [ 246, 252 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O46674" }, { "db_name": "UniProt", "db_id": "O55143" }, { "db_name": "UniProt", "db_id": "P11507" }, { "db_name": "UniProt", "db_id": "P11607" }, { "db_name": "UniProt", "db_id": "P16615" }, { "db_name": "UniProt", "db_id": "P20647" }, { "db_name": "UniProt", "db_id": "Q00779" }, { "db_name": "UniProt", "db_id": "Q03669" } ] }, { "id": "DS.d926.s1.e3", "type": "compound", "text": [ "sucrose" ], "offsets": [ [ 330, 337 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5988" } ] } ]
[]
[]
[]
DS.d927
18752971
[ { "id": "DS.d927.s0", "type": "", "text": [ "The recent approval of sunitinib, sorafenib, temsirolimus and bevacizumab in combination with IFN-alpha has revolutionized the management of renal cell carcinoma." ], "offsets": [ [ 0, 162 ] ] } ]
[ { "id": "DS.d927.s0.e0", "type": "compound", "text": [ "sunitinib" ], "offsets": [ [ 23, 32 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5329102" } ] }, { "id": "DS.d927.s0.e1", "type": "compound", "text": [ "sorafenib" ], "offsets": [ [ 34, 43 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "216239" } ] }, { "id": "DS.d927.s0.e2", "type": "compound", "text": [ "temsirolimus" ], "offsets": [ [ 45, 57 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "148191" }, { "db_name": "PubChem", "db_id": "6918289" }, { "db_name": "PubChem", "db_id": "18293306" }, { "db_name": "PubChem", "db_id": "23724530" }, { "db_name": "PubChem", "db_id": "24847874" }, { "db_name": "PubChem", "db_id": "53486199" }, { "db_name": "PubChem", "db_id": "54608508" } ] }, { "id": "DS.d927.s0.e3", "type": "protein", "text": [ "IFN-alpha" ], "offsets": [ [ 94, 103 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P35849" } ] } ]
[]
[]
[]
DS.d928
18753126
[ { "id": "DS.d928.s0", "type": "", "text": [ "Here we report identification of the first three in vivo non-histone protein substrates of lysine propionylation in eukaryotic cells: p53, p300, and CREB-binding protein." ], "offsets": [ [ 0, 170 ] ] }, { "id": "DS.d928.s1", "type": "", "text": [ "p300 was able to perform autopropionylation on lysine residues in cells." ], "offsets": [ [ 171, 243 ] ] } ]
[ { "id": "DS.d928.s0.e0", "type": "compound", "text": [ "lysine" ], "offsets": [ [ 91, 97 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "866" }, { "db_name": "PubChem", "db_id": "5962" } ] }, { "id": "DS.d928.s0.e1", "type": "protein", "text": [ "p53" ], "offsets": [ [ 134, 137 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O09185" }, { "db_name": "UniProt", "db_id": "O12946" }, { "db_name": "UniProt", "db_id": "O57538" }, { "db_name": "UniProt", "db_id": "O93379" }, { "db_name": "UniProt", "db_id": "P02340" }, { "db_name": "UniProt", "db_id": "P04637" }, { "db_name": "UniProt", "db_id": "P10361" }, { "db_name": "UniProt", "db_id": "P19558" }, { "db_name": "UniProt", "db_id": "P19559" }, { "db_name": "UniProt", "db_id": "P56423" }, { "db_name": "UniProt", "db_id": "P56424" }, { "db_name": "UniProt", "db_id": "P61260" }, { "db_name": "UniProt", "db_id": "P79820" }, { "db_name": "UniProt", "db_id": "P79892" }, { "db_name": "UniProt", "db_id": "Q29537" }, { "db_name": "UniProt", "db_id": "Q42578" }, { "db_name": "UniProt", "db_id": "Q8SPZ3" }, { "db_name": "UniProt", "db_id": "Q92143" }, { "db_name": "UniProt", "db_id": "Q9TTA1" }, { "db_name": "UniProt", "db_id": "Q9TUB2" }, { "db_name": "UniProt", "db_id": "Q9W678" }, { "db_name": "UniProt", "db_id": "Q9W679" } ] }, { "id": "DS.d928.s0.e2", "type": "protein", "text": [ "p300" ], "offsets": [ [ 139, 143 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q01705" }, { "db_name": "UniProt", "db_id": "Q09472" } ] }, { "id": "DS.d928.s0.e3", "type": "protein", "text": [ "CREB-binding protein" ], "offsets": [ [ 149, 169 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P45481" }, { "db_name": "UniProt", "db_id": "Q92793" } ] }, { "id": "DS.d928.s1.e0", "type": "protein", "text": [ "p300" ], "offsets": [ [ 171, 175 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q01705" }, { "db_name": "UniProt", "db_id": "Q09472" } ] }, { "id": "DS.d928.s1.e1", "type": "compound", "text": [ "lysine" ], "offsets": [ [ 218, 224 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "866" }, { "db_name": "PubChem", "db_id": "5962" } ] } ]
[]
[]
[ { "id": "DS.d928.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d928.s0.e0", "arg2_id": "DS.d928.s0.e3", "normalized": [] }, { "id": "DS.d928.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d928.s0.e0", "arg2_id": "DS.d928.s0.e1", "normalized": [] }, { "id": "DS.d928.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d928.s0.e0", "arg2_id": "DS.d928.s0.e2", "normalized": [] }, { "id": "DS.d928.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d928.s1.e1", "arg2_id": "DS.d928.s1.e0", "normalized": [] } ]
DS.d929
18753604
[ { "id": "DS.d929.s0", "type": "", "text": [ "This study determined the effects of the estrous cycle, pregnancy, progesterone (P4), and interferon tau (IFNT) on expression of both facilitative (SLC2A1, SLC2A3, and SLC2A4) and sodium-dependent (SLC5A1 and SLC5A11) glucose transporters in ovine uterine endometria from Days 10 to 16 of the estrous cycle and Days 10 to 20 of pregnancy, as well as in conceptuses from Days 10 to 20 of pregnancy." ], "offsets": [ [ 0, 397 ] ] } ]
[ { "id": "DS.d929.s0.e0", "type": "compound", "text": [ "progesterone" ], "offsets": [ [ 67, 79 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "5994" } ] }, { "id": "DS.d929.s0.e1", "type": "protein", "text": [ "tau" ], "offsets": [ [ 101, 104 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P10637" }, { "db_name": "UniProt", "db_id": "P16525" }, { "db_name": "UniProt", "db_id": "P19332" }, { "db_name": "UniProt", "db_id": "P58384" } ] }, { "id": "DS.d929.s0.e2", "type": "protein", "text": [ "IFNT" ], "offsets": [ [ 106, 110 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O46633" }, { "db_name": "UniProt", "db_id": "P28171" }, { "db_name": "UniProt", "db_id": "P28172" }, { "db_name": "UniProt", "db_id": "Q95187" } ] }, { "id": "DS.d929.s0.e3", "type": "protein", "text": [ "SLC2A1" ], "offsets": [ [ 148, 154 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P11166" }, { "db_name": "UniProt", "db_id": "P13355" }, { "db_name": "UniProt", "db_id": "P20303" }, { "db_name": "UniProt", "db_id": "P27674" }, { "db_name": "UniProt", "db_id": "P46896" }, { "db_name": "UniProt", "db_id": "P79365" } ] }, { "id": "DS.d929.s0.e4", "type": "protein", "text": [ "SLC2A3" ], "offsets": [ [ 156, 162 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O62787" }, { "db_name": "UniProt", "db_id": "P11169" }, { "db_name": "UniProt", "db_id": "P28568" }, { "db_name": "UniProt", "db_id": "P47842" }, { "db_name": "UniProt", "db_id": "P47843" }, { "db_name": "UniProt", "db_id": "P58352" }, { "db_name": "UniProt", "db_id": "Q5R608" }, { "db_name": "UniProt", "db_id": "Q9XSC2" } ] }, { "id": "DS.d929.s0.e5", "type": "protein", "text": [ "SLC2A4" ], "offsets": [ [ 168, 174 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P14672" }, { "db_name": "UniProt", "db_id": "Q27994" }, { "db_name": "UniProt", "db_id": "Q9XST2" }, { "db_name": "UniProt", "db_id": "Q9XT10" } ] }, { "id": "DS.d929.s0.e6", "type": "protein", "text": [ "SLC5A1" ], "offsets": [ [ 198, 204 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P11170" }, { "db_name": "UniProt", "db_id": "P13866" }, { "db_name": "UniProt", "db_id": "P26429" }, { "db_name": "UniProt", "db_id": "P53791" } ] }, { "id": "DS.d929.s0.e7", "type": "protein", "text": [ "glucose transporters" ], "offsets": [ [ 218, 238 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P23586" } ] } ]
[]
[]
[ { "id": "DS.d929.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d929.s0.e0", "arg2_id": "DS.d929.s0.e3", "normalized": [] }, { "id": "DS.d929.s0.i1", "type": "compound-protein-interaction", "arg1_id": "DS.d929.s0.e0", "arg2_id": "DS.d929.s0.e4", "normalized": [] }, { "id": "DS.d929.s0.i2", "type": "compound-protein-interaction", "arg1_id": "DS.d929.s0.e0", "arg2_id": "DS.d929.s0.e6", "normalized": [] }, { "id": "DS.d929.s0.i3", "type": "compound-protein-interaction", "arg1_id": "DS.d929.s0.e0", "arg2_id": "DS.d929.s0.e7", "normalized": [] }, { "id": "DS.d929.s0.i4", "type": "compound-protein-interaction", "arg1_id": "DS.d929.s0.e0", "arg2_id": "DS.d929.s0.e5", "normalized": [] } ]
DS.d930
18753675
[ { "id": "DS.d930.s0", "type": "", "text": [ "In CD36-D patients, plasma triglycerides, apolipoprotein B-48 (apoB-48), free fatty acids (FFAs), and free glycerol levels were much higher after OFL than those of controls, along with increases in chylomicron (CM) remnants and small dense low-density lipoprotein (sdLDL) particles." ], "offsets": [ [ 0, 282 ] ] } ]
[ { "id": "DS.d930.s0.e0", "type": "protein", "text": [ "CD36" ], "offsets": [ [ 3, 7 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P16671" }, { "db_name": "UniProt", "db_id": "P26201" }, { "db_name": "UniProt", "db_id": "P70110" } ] }, { "id": "DS.d930.s0.e1", "type": "protein", "text": [ "apolipoprotein B-48" ], "offsets": [ [ 42, 61 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P04114" } ] }, { "id": "DS.d930.s0.e2", "type": "protein", "text": [ "apoB-48" ], "offsets": [ [ 63, 70 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P04114" } ] }, { "id": "DS.d930.s0.e3", "type": "compound", "text": [ "glycerol" ], "offsets": [ [ 107, 115 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "753" } ] } ]
[]
[]
[]
DS.d931
18753676
[ { "id": "DS.d931.s0", "type": "", "text": [ "Identification of SMEK2 as a candidate gene for regulation of responsiveness to dietary cholesterol in rats." ], "offsets": [ [ 0, 108 ] ] }, { "id": "DS.d931.s1", "type": "", "text": [ "Here we narrowed Dihc2 to a region including 33 genes and predicted transcripts and identified RGD1309450_predicted, a homologous gene of SMEK2, as a strong candidate for responsiveness to dietary cholesterol." ], "offsets": [ [ 109, 318 ] ] } ]
[ { "id": "DS.d931.s0.e0", "type": "protein", "text": [ "SMEK2" ], "offsets": [ [ 18, 23 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q5MIZ7" } ] }, { "id": "DS.d931.s0.e1", "type": "compound", "text": [ "cholesterol" ], "offsets": [ [ 88, 99 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "304" }, { "db_name": "PubChem", "db_id": "5997" }, { "db_name": "PubChem", "db_id": "6432564" }, { "db_name": "PubChem", "db_id": "11025495" } ] }, { "id": "DS.d931.s1.e0", "type": "protein", "text": [ "SMEK2" ], "offsets": [ [ 247, 252 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q5MIZ7" } ] }, { "id": "DS.d931.s1.e1", "type": "compound", "text": [ "cholesterol" ], "offsets": [ [ 306, 317 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "304" }, { "db_name": "PubChem", "db_id": "5997" }, { "db_name": "PubChem", "db_id": "6432564" }, { "db_name": "PubChem", "db_id": "11025495" } ] } ]
[]
[]
[ { "id": "DS.d931.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d931.s0.e1", "arg2_id": "DS.d931.s0.e0", "normalized": [] }, { "id": "DS.d931.s1.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d931.s1.e1", "arg2_id": "DS.d931.s1.e0", "normalized": [] } ]
DS.d932
18753737
[ { "id": "DS.d932.s0", "type": "", "text": [ "Testosterone is a strong correlate of ghrelin levels in men and postmenopausal women." ], "offsets": [ [ 0, 85 ] ] } ]
[ { "id": "DS.d932.s0.e0", "type": "compound", "text": [ "Testosterone" ], "offsets": [ [ 0, 12 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6013" } ] }, { "id": "DS.d932.s0.e1", "type": "protein", "text": [ "ghrelin" ], "offsets": [ [ 38, 45 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "Q6BEG6" }, { "db_name": "UniProt", "db_id": "Q6BEG7" }, { "db_name": "UniProt", "db_id": "Q9BDJ6" }, { "db_name": "UniProt", "db_id": "Q9BEF8" }, { "db_name": "UniProt", "db_id": "Q9EQX0" }, { "db_name": "UniProt", "db_id": "Q9GKY5" }, { "db_name": "UniProt", "db_id": "Q9QYH7" }, { "db_name": "UniProt", "db_id": "Q9UBU3" } ] } ]
[]
[]
[ { "id": "DS.d932.s0.i0", "type": "compound-protein-interaction", "arg1_id": "DS.d932.s0.e0", "arg2_id": "DS.d932.s0.e1", "normalized": [] } ]
DS.d933
18754081
[ { "id": "DS.d933.s0", "type": "", "text": [ "Up to 72% hexose yield and 94% pentose yield were obtained using modified steam explosion with 2% sulfuric acid at 140 degrees C for 30 min and enzymatic hydrolysis with cellulase (15 filter per unit (FPU)/g cellulose) and beta-glucosidase (50 cellobiose units (CBU)/g cellulose)." ], "offsets": [ [ 0, 280 ] ] } ]
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[]
[]
[]
DS.d934
18754092
[ { "id": "DS.d934.s0", "type": "", "text": [ "Glutathione (GSH), catalase (CAT), and malondialdehyde (MDA) activities in blood were measured." ], "offsets": [ [ 0, 95 ] ] }, { "id": "DS.d934.s1", "type": "", "text": [ "Catalase, myeloperoxidase (MPO), glutathione peroxidase (GSH-Px), glutathione reductase (GR), malondialdehyde, and nitric oxide (NO) activities were measured from tissue samples." ], "offsets": [ [ 96, 274 ] ] } ]
[ { "id": "DS.d934.s0.e0", "type": "compound", "text": [ "Glutathione" ], "offsets": [ [ 0, 11 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "124886" } ] }, { "id": "DS.d934.s0.e1", "type": "compound", "text": [ "GSH" ], "offsets": [ [ 13, 16 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "124886" } ] }, { "id": "DS.d934.s0.e2", "type": "protein", "text": [ "catalase" ], "offsets": [ [ 19, 27 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O24339" }, { "db_name": "UniProt", "db_id": "O52762" }, { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O68146" }, { "db_name": "UniProt", "db_id": "O77229" }, { "db_name": "UniProt", "db_id": "O93662" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P04762" }, { "db_name": "UniProt", "db_id": "P07145" }, { "db_name": "UniProt", "db_id": "P0A323" }, { "db_name": "UniProt", "db_id": "P0A324" }, { "db_name": "UniProt", "db_id": "P0A325" }, { "db_name": "UniProt", "db_id": "P0A326" }, { "db_name": "UniProt", "db_id": "P0A327" }, { "db_name": "UniProt", "db_id": "P11934" }, { "db_name": "UniProt", "db_id": "P17336" }, { "db_name": "UniProt", "db_id": "P24168" }, { "db_name": "UniProt", "db_id": "P24270" }, { "db_name": "UniProt", "db_id": "P25890" }, { "db_name": "UniProt", "db_id": "P29422" }, { "db_name": "UniProt", "db_id": "P30265" }, { "db_name": "UniProt", "db_id": "P30266" }, { "db_name": "UniProt", "db_id": "P32290" }, { "db_name": "UniProt", "db_id": "P42321" }, { "db_name": "UniProt", "db_id": "P44390" }, { "db_name": "UniProt", "db_id": "P45737" }, { "db_name": "UniProt", "db_id": "P45739" }, { "db_name": "UniProt", "db_id": "P55304" }, { "db_name": "UniProt", "db_id": "P55306" }, { "db_name": "UniProt", "db_id": "P55310" }, { "db_name": "UniProt", "db_id": "P55311" }, { "db_name": "UniProt", "db_id": "P55313" }, { "db_name": "UniProt", "db_id": "P77872" }, { "db_name": "UniProt", "db_id": "P81138" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q27710" }, { "db_name": "UniProt", "db_id": "Q49XC1" }, { "db_name": "UniProt", "db_id": "Q4L643" }, { "db_name": "UniProt", "db_id": "Q59296" }, { "db_name": "UniProt", "db_id": "Q59337" }, { "db_name": "UniProt", "db_id": "Q59602" }, { "db_name": "UniProt", "db_id": "Q59714" }, { "db_name": "UniProt", "db_id": "Q5HG86" }, { "db_name": "UniProt", "db_id": "Q5HPK8" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q6G9M4" }, { "db_name": "UniProt", "db_id": "Q6GH72" }, { "db_name": "UniProt", "db_id": "Q7A5T2" }, { "db_name": "UniProt", "db_id": "Q8CPD0" }, { "db_name": "UniProt", "db_id": "Q8FWU0" }, { "db_name": "UniProt", "db_id": "Q8NWV5" }, { "db_name": "UniProt", "db_id": "Q8X1P0" }, { "db_name": "UniProt", "db_id": "Q8Y3P9" }, { "db_name": "UniProt", "db_id": "Q926X0" }, { "db_name": "UniProt", "db_id": "Q99UE2" }, { "db_name": "UniProt", "db_id": "Q9AXH0" }, { "db_name": "UniProt", "db_id": "Q9KW19" }, { "db_name": "UniProt", "db_id": "Q9L4S1" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PT92" }, { "db_name": "UniProt", "db_id": "Q9PWF7" }, { "db_name": "UniProt", "db_id": "Q9Z598" }, { "db_name": "UniProt", "db_id": "Q9ZKX5" }, { "db_name": "UniProt", "db_id": "Q9ZN99" } ] }, { "id": "DS.d934.s0.e3", "type": "protein", "text": [ "CAT" ], "offsets": [ [ 29, 32 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P00485" }, { "db_name": "UniProt", "db_id": "P00486" }, { "db_name": "UniProt", "db_id": "P00487" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P06135" }, { "db_name": "UniProt", "db_id": "P07641" }, { "db_name": "UniProt", "db_id": "P11504" }, { "db_name": "UniProt", "db_id": "P20074" }, { "db_name": "UniProt", "db_id": "P22782" }, { "db_name": "UniProt", "db_id": "P25309" }, { "db_name": "UniProt", "db_id": "P25819" }, { "db_name": "UniProt", "db_id": "P26825" }, { "db_name": "UniProt", "db_id": "P26826" }, { "db_name": "UniProt", "db_id": "P32796" }, { "db_name": "UniProt", "db_id": "P36882" }, { "db_name": "UniProt", "db_id": "P36883" }, { "db_name": "UniProt", "db_id": "P43155" }, { "db_name": "UniProt", "db_id": "P47934" }, { "db_name": "UniProt", "db_id": "P49417" }, { "db_name": "UniProt", "db_id": "P52826" }, { "db_name": "UniProt", "db_id": "P58777" }, { "db_name": "UniProt", "db_id": "P62577" }, { "db_name": "UniProt", "db_id": "P62578" }, { "db_name": "UniProt", "db_id": "P62579" }, { "db_name": "UniProt", "db_id": "P62580" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q00614" }, { "db_name": "UniProt", "db_id": "Q02736" }, { "db_name": "UniProt", "db_id": "Q03058" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q704S8" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PWF7" } ] }, { "id": "DS.d934.s0.e4", "type": "compound", "text": [ "malondialdehyde" ], "offsets": [ [ 39, 54 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "10964" } ] }, { "id": "DS.d934.s1.e0", "type": "protein", "text": [ "Catalase" ], "offsets": [ [ 96, 104 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O24339" }, { "db_name": "UniProt", "db_id": "O52762" }, { "db_name": "UniProt", "db_id": "O62839" }, { "db_name": "UniProt", "db_id": "O68146" }, { "db_name": "UniProt", "db_id": "O77229" }, { "db_name": "UniProt", "db_id": "O93662" }, { "db_name": "UniProt", "db_id": "O97492" }, { "db_name": "UniProt", "db_id": "P00432" }, { "db_name": "UniProt", "db_id": "P04040" }, { "db_name": "UniProt", "db_id": "P04762" }, { "db_name": "UniProt", "db_id": "P07145" }, { "db_name": "UniProt", "db_id": "P0A323" }, { "db_name": "UniProt", "db_id": "P0A324" }, { "db_name": "UniProt", "db_id": "P0A325" }, { "db_name": "UniProt", "db_id": "P0A326" }, { "db_name": "UniProt", "db_id": "P0A327" }, { "db_name": "UniProt", "db_id": "P11934" }, { "db_name": "UniProt", "db_id": "P17336" }, { "db_name": "UniProt", "db_id": "P24168" }, { "db_name": "UniProt", "db_id": "P24270" }, { "db_name": "UniProt", "db_id": "P25890" }, { "db_name": "UniProt", "db_id": "P29422" }, { "db_name": "UniProt", "db_id": "P30265" }, { "db_name": "UniProt", "db_id": "P30266" }, { "db_name": "UniProt", "db_id": "P32290" }, { "db_name": "UniProt", "db_id": "P42321" }, { "db_name": "UniProt", "db_id": "P44390" }, { "db_name": "UniProt", "db_id": "P45737" }, { "db_name": "UniProt", "db_id": "P45739" }, { "db_name": "UniProt", "db_id": "P55304" }, { "db_name": "UniProt", "db_id": "P55306" }, { "db_name": "UniProt", "db_id": "P55310" }, { "db_name": "UniProt", "db_id": "P55311" }, { "db_name": "UniProt", "db_id": "P55313" }, { "db_name": "UniProt", "db_id": "P77872" }, { "db_name": "UniProt", "db_id": "P81138" }, { "db_name": "UniProt", "db_id": "P90682" }, { "db_name": "UniProt", "db_id": "Q27710" }, { "db_name": "UniProt", "db_id": "Q49XC1" }, { "db_name": "UniProt", "db_id": "Q4L643" }, { "db_name": "UniProt", "db_id": "Q59296" }, { "db_name": "UniProt", "db_id": "Q59337" }, { "db_name": "UniProt", "db_id": "Q59602" }, { "db_name": "UniProt", "db_id": "Q59714" }, { "db_name": "UniProt", "db_id": "Q5HG86" }, { "db_name": "UniProt", "db_id": "Q5HPK8" }, { "db_name": "UniProt", "db_id": "Q5RF10" }, { "db_name": "UniProt", "db_id": "Q64405" }, { "db_name": "UniProt", "db_id": "Q6G9M4" }, { "db_name": "UniProt", "db_id": "Q6GH72" }, { "db_name": "UniProt", "db_id": "Q7A5T2" }, { "db_name": "UniProt", "db_id": "Q8CPD0" }, { "db_name": "UniProt", "db_id": "Q8FWU0" }, { "db_name": "UniProt", "db_id": "Q8NWV5" }, { "db_name": "UniProt", "db_id": "Q8X1P0" }, { "db_name": "UniProt", "db_id": "Q8Y3P9" }, { "db_name": "UniProt", "db_id": "Q926X0" }, { "db_name": "UniProt", "db_id": "Q99UE2" }, { "db_name": "UniProt", "db_id": "Q9AXH0" }, { "db_name": "UniProt", "db_id": "Q9KW19" }, { "db_name": "UniProt", "db_id": "Q9L4S1" }, { "db_name": "UniProt", "db_id": "Q9M5L6" }, { "db_name": "UniProt", "db_id": "Q9PT92" }, { "db_name": "UniProt", "db_id": "Q9PWF7" }, { "db_name": "UniProt", "db_id": "Q9Z598" }, { "db_name": "UniProt", "db_id": "Q9ZKX5" }, { "db_name": "UniProt", "db_id": "Q9ZN99" } ] }, { "id": "DS.d934.s1.e1", "type": "protein", "text": [ "MPO" ], "offsets": [ [ 123, 126 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "P05164" }, { "db_name": "UniProt", "db_id": "P11247" } ] }, { "id": "DS.d934.s1.e2", "type": "protein", "text": [ "glutathione peroxidase" ], "offsets": [ [ 129, 151 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O32770" }, { "db_name": "UniProt", "db_id": "O59858" }, { "db_name": "UniProt", "db_id": "Q00277" }, { "db_name": "UniProt", "db_id": "Q9CFV1" } ] }, { "id": "DS.d934.s1.e3", "type": "protein", "text": [ "glutathione reductase" ], "offsets": [ [ 162, 183 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O15770" }, { "db_name": "UniProt", "db_id": "P06715" }, { "db_name": "UniProt", "db_id": "P11804" }, { "db_name": "UniProt", "db_id": "P23189" }, { "db_name": "UniProt", "db_id": "P41921" }, { "db_name": "UniProt", "db_id": "P43783" }, { "db_name": "UniProt", "db_id": "P48638" }, { "db_name": "UniProt", "db_id": "P48639" }, { "db_name": "UniProt", "db_id": "P70619" }, { "db_name": "UniProt", "db_id": "P78965" }, { "db_name": "UniProt", "db_id": "Q60151" }, { "db_name": "UniProt", "db_id": "Q6BPI1" }, { "db_name": "UniProt", "db_id": "Q6C5H4" }, { "db_name": "UniProt", "db_id": "Q6FRV2" }, { "db_name": "UniProt", "db_id": "Q6HA23" }, { "db_name": "UniProt", "db_id": "Q74ZK4" }, { "db_name": "UniProt", "db_id": "Q873E8" }, { "db_name": "UniProt", "db_id": "Q94655" } ] }, { "id": "DS.d934.s1.e4", "type": "compound", "text": [ "malondialdehyde" ], "offsets": [ [ 190, 205 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "10964" } ] }, { "id": "DS.d934.s1.e5", "type": "compound", "text": [ "nitric oxide" ], "offsets": [ [ 211, 223 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "145068" } ] } ]
[]
[]
[]
DS.d935
18754101
[ { "id": "DS.d935.s0", "type": "", "text": [ "In this study we examined the possible antigenotoxic effect of selenium (Se) in rats chronically exposed to low levels of methylmercury (MeHg) and the association between glutathione peroxidase (GSH-Px) activity and DNA lesions (via comet assay) in the same exposed animals." ], "offsets": [ [ 0, 274 ] ] } ]
[ { "id": "DS.d935.s0.e0", "type": "compound", "text": [ "methylmercury" ], "offsets": [ [ 122, 135 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "7906" } ] }, { "id": "DS.d935.s0.e1", "type": "compound", "text": [ "MeHg" ], "offsets": [ [ 137, 141 ] ], "normalized": [ { "db_name": "PubChem", "db_id": "6860" } ] }, { "id": "DS.d935.s0.e2", "type": "protein", "text": [ "glutathione peroxidase" ], "offsets": [ [ 171, 193 ] ], "normalized": [ { "db_name": "UniProt", "db_id": "O32770" }, { "db_name": "UniProt", "db_id": "O59858" }, { "db_name": "UniProt", "db_id": "Q00277" }, { "db_name": "UniProt", "db_id": "Q9CFV1" } ] } ]
[]
[]
[]