text: This includes nonribosomal peptide synthetases (NRPS) and polyketide synthases (PKS) required for the formation of the << benzopyranopyrrole >> core unit, as well as a suite of tailoring enzymes (e.g., four halogenases, an O-methyltransferase, and an [[ N-glycosyltransferase ]]) necessary for further modifications of the core structure.