text: Estimated affinities for the fast-inactivated channel state were 81 nM, 312 nM and 227 nM for 4-iodopropofol, 4-bromopropofol and << 4-chloropropofol >> in [[ Na(V)1.4 ]], and 450 nM for 4-chloropropofol in Na(V)1.2.