text: The porcine heart malate dehydrogenase (MDH) refolding assay revealed that compound 1l inhibited << human Hsp60 >> chaperone activity (IC(50): 6.80 ± 0.25 μM) and this inhibition activity was higher than that of [[ ETB ]] (IC(50): 10.9 ± 0.63 μM).