text: Blood pressure was increased in rats exposed to IH, and treatment with the << PDK-1 >> inhibitor OSU-03012 [[[ 2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl}-acetamide ]]] (33 mg/day) lowered blood pressure in IH but not sham group rats.