text: Treatment with adenosine dialdehyde (AdOx), an inhibitor of transmethylation-suppressive << adenosylhomocysteine (SAH) hydrolase >> (SAHH), enhanced the level of [[ SAH ]] and effectively blocked the proliferation, migration, and invasion of cancer cells; the treatment also induced the differentiation of C6 glioma cells and suppressed the neovascular genesis of eggs in a dose-dependent manner.