text: For some, pharmacologic inhibitors are available, including sorafenib for BRAF, farnesyltransferase inhibitors for NRAS, PD-0325901 for mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, << rapamycin >> analogues for [[ mammalian target of rapamycin ]], and agents that inhibit either vascular endothelial growth factor or its receptors.