text: Treatment with << adenosine dialdehyde >> (AdOx), an inhibitor of transmethylation-suppressive adenosylhomocysteine (SAH) hydrolase ([[ SAHH ]]), enhanced the level of SAH and effectively blocked the proliferation, migration, and invasion of cancer cells; the treatment also induced the differentiation of C6 glioma cells and suppressed the neovascular genesis of eggs in a dose-dependent manner.