text: This includes nonribosomal peptide synthetases (NRPS) and polyketide synthases (PKS) required for the formation of the << benzopyranopyrrole >> core unit, as well as a suite of tailoring enzymes (e.g., four halogenases, an [[ O-methyltransferase ]], and an N-glycosyltransferase) necessary for further modifications of the core structure.