Among the current << AT1 >> receptor antagonists, the rank order of the relative binding affinities (highest affinity = 1) is: candesartan 1, [[ telmisartan ]] 10, E3174 (the active metabolite of losartan) 10, tasosartan 20, losartan 50, eprosartan 100 and the prodrug candesartan cilexetil 280.