text: METHODS: << COX-1 >> inhibition was determined by measuring thromboxane B2 (TXB2)-generation from clotting whole blood ex vivo after single oral doses of 7.5 and 15 mg [[ meloxicam ]] and 75 mg diclofenac and at steady state (15 mg meloxicam daily and 150 mg diclofenac daily).