text: Patch-clamp analysis using inside-out recording configuration showed that << mitiglinide >> inhibits the [[ Kir6.2 ]]/SUR1 channel currents in a dose-dependent manner (IC50 value, 100 nM) but does not significantly inhibit either Kir6.2/SUR2A or Kir6.2/SUR2B channel currents even at high doses (more than 10 microM).