text: (-)-6-(7-Methoxy-2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-4-yl)-5-methyl-4,5-dihydropyridazin-3(2H)-one (<< KCA-1490 >>) exhibits moderate dual [[ PDE3/4 ]]-inhibitory activity and promises as a combined bronchodilatory/anti-inflammatory agent.