text: In this report, we evaluated the growth-inhibitory effects of << sulindac sulfide >>, a [[ COX-1 ]] and COX-2 inhibitor; exisulind (sulindac sulfone), a novel proapoptotic agent that does not inhibit COX enzymes; and nordihydroguaiaretic acid (NDGA), a lipoxygenase inhibitor on human lung cancer cell lines.