Category: Treatment - Chloroquine
Question: what is the effect of chloroquine(cq) and hydroxychloroquine(hcq) on endosomal maturation and endocytosis in covid treatment
Answers: in the lab, these drugs have been shown to prevent the growth of the virus that causes covid. there are a few reports of patients with covid who received these drugs and improved. some are reports of groups of patients, all of whom received the drug. it is not known whether it was the drug that led to the improvement or whether there were other factors involved. , chloroquine phosphate is only approved for the treatment of malaria, and hydroxychloroquine sulfate is only approved for the treatment of malaria, lupus, and rheumatoid arthritis. , no. hydroxychloroquine sulfate and some versions of chloroquine phosphate are fda approved to treat malaria. , since acidification is crucial for endosome maturation and function, we surmise that endosome maturation might be blocked at intermediate stages of endocytosis,, compare the antiviral activity of cq versus hcq, the dose response curves,  hcq is a safe and successful anti inflammatory agent